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Home > Nitro Compounds > 56-57-5
56-57-5 | 4-Nitroquinoline N-Oxide
CAS No: 56-57-5 Catalog No: AG003LWO MDL No:MFCD00006738
Product Description
Catalog Number:
AG003LWO
Chemical Name:
4-Nitroquinoline N-Oxide
CAS Number:
56-57-5
Molecular Formula:
C9H6N2O3
Molecular Weight:
190.1555
MDL Number:
MFCD00006738
IUPAC Name:
4-nitro-1-oxidoquinolin-1-ium
InChI:
InChI=1S/C9H6N2O3/c12-10-6-5-9(11(13)14)7-3-1-2-4-8(7)10/h1-6H
InChI Key:
YHQDZJICGQWFHK-UHFFFAOYSA-N
SMILES:
O=N(=O)c1cc[n+](c2c1cccc2)[O-]
EC Number:
200-281-1
UNII:
X5081510EV
NSC Number:
19645
RTECS Number:
VC2100000
UN Number:
2811
Properties
Complexity:
229
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
190.038g/mol
Formal Charge:
0
Heavy Atom Count:
14
Hydrogen Bond Acceptor Count:
3
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
190.158g/mol
Monoisotopic Mass:
190.038g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
71.3A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.1
Literature
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| 4-NQO induces apoptosis via p53-dependent mitochondrial signaling pathway. | Toxicology 20070212 |
| Connexin expression in mouse lung tumor. | Cancer letters 20070208 |
| Frequent mutation of p16(CDKN2A) exon 1 during rat tongue carcinogenesis induced by 4-nitroquinoline-1-oxide. | Molecular carcinogenesis 20070201 |
| Effects of sex hormones on rat tongue carcinoma induced by 4-nitroquinoline 1-oxide (4NQO). | The Bulletin of Tokyo Dental College 20070201 |
| A method to distinguish between the de novo induction of thymidine kinase mutants and the selection of pre-existing thymidine kinase mutants in the mouse lymphoma assay. | Mutation research 20070110 |
| 4-Nitroquinoline-1-oxide-induced mutagen sensitivity and risk of nonmelanoma skin cancer: a case-control analysis. | The Journal of investigative dermatology 20070101 |
| Methyl-substituted 4-nitropyridine N-oxides as ligands: structural, spectroscopic, magnetic and cytotoxic characteristics of copper(II) complexes. | Journal of inorganic biochemistry 20070101 |
| Response of lymphocyte subsets and cytokines to Shenyang prescription in Sprague-Dawley rats with tongue squamous cell carcinomas induced by 4NQO. | BMC cancer 20070101 |
| Urodele p53 tolerates amino acid changes found in p53 variants linked to human cancer. | BMC evolutionary biology 20070101 |
| Initial in vitro screening approach to investigate the potential health and environmental hazards of Enviroxtrade mark - a nanoparticulate cerium oxide diesel fuel additive. | Particle and fibre toxicology 20070101 |
| Deletion of the chromatin remodeling gene SPT10 sensitizes yeast cells to a subclass of DNA-damaging agents. | Environmental and molecular mutagenesis 20061201 |
| Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. | Journal of molecular graphics & modelling 20061101 |
| Nitrocompound activation by cell-free extracts of nitroreductase-proficient Salmonella typhimurium strains. | Mutagenesis 20061101 |
| Parp-1 deficiency does not increase the frequency of tumors in the oral cavity and esophagus of ICR/129Sv mice by 4-nitroquinoline 1-oxide, a carcinogen producing bulky adducts. | Cancer letters 20060908 |
| Chemopreventive efficacy of all-trans-retinoic acid in biodegradable microspheres against epithelial cancers: results in a 4-nitroquinoline 1-oxide-induced oral carcinogenesis model. | International journal of pharmaceutics 20060831 |
| Modulatory efficacy of green tea polyphenols on glycoconjugates and immunological markers in 4-Nitroquinoline 1-oxide-induced oral carcinogenesis-A therapeutic approach. | Chemico-biological interactions 20060825 |
| Mutagenicity and antimutagenic effect of soymilk fermented with lactic acid bacteria and bifidobacteria. | International journal of food microbiology 20060815 |
| 4-nitroquinoline-1-oxide induced experimental oral carcinogenesis. | Oral oncology 20060801 |
| Selective loss of resistant alleles at p15INK4B and p16INK4A genes in chemically-induced rat tongue cancers. | Oral oncology 20060801 |
| Role of the ABC transporter TruMDR2 in terbinafine, 4-nitroquinoline N-oxide and ethidium bromide susceptibility in Trichophyton rubrum. | Journal of medical microbiology 20060801 |
| Development of genotoxicity test procedures with Episkin, a reconstructed human skin model: towards new tools for in vitro risk assessment of dermally applied compounds? | Mutation research 20060714 |
| Zinc deficiency potentiates induction and progression of lingual and esophageal tumors in p53-deficient mice. | Carcinogenesis 20060701 |
| Suppression on the mutagenicity of 4-nitroquinoline-N-oxide by the methanol extracts of soybean koji prepared with various filamentous fungi. | International journal of food microbiology 20060701 |
| Use of fish in vitro hepatocyte assays to detect multi-endpoint toxicity in Slovenian river sediments. | Marine environmental research 20060701 |
| Kre29p is a novel nuclear protein involved in DNA repair and mitotic fidelity in Candida glabrata. | Current genetics 20060701 |
| Immunohistochemical evaluation of metallothionein in palatal mucosal cells of mice treated with 4NQO. | Medicina oral, patologia oral y cirugia bucal 20060701 |
| 4-nitroquinoline-1-oxide induces the formation of cellular topoisomerase I-DNA cleavage complexes. | Cancer research 20060701 |
| Mutagen sensitivity has high heritability: evidence from a twin study. | Cancer research 20060615 |
| 4-Nitroquinoline 1-oxide forms 8-hydroxydeoxyguanosine in human fibroblasts through reactive oxygen species. | Toxicological sciences : an official journal of the Society of Toxicology 20060601 |
| p53 Transgenic mice are highly susceptible to 4-nitroquinoline-1-oxide-induced oral cancer. | Molecular cancer research : MCR 20060601 |
| Effects of co-exposure to extremely low frequency (50 Hz) magnetic fields and xenobiotics determined in vitro by the alkaline comet assay. | The Science of the total environment 20060515 |
| Interaction of 4-nitroquinoline-1-oxide with indole derivatives and some related biomolecules: a study with magnetic field. | The journal of physical chemistry. B 20060504 |
| Broken hyphae of the basidiomycete Crinipellis perniciosa allow quantitative assay of toxicity. | Current microbiology 20060501 |
| Ultrastructural changes of the palatal mucosa following application of 4-nitroquinoline-l-oxide (4NQO) in rats subjected to major salivary gland excision. | Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20060401 |
| An animal model for the rapid induction of tongue neoplasms in human c-Ha-ras proto-oncogene transgenic rats by 4-nitroquinoline 1-oxide: its potential use for preclinical chemoprevention studies. | Carcinogenesis 20060301 |
| Head and neck cancer cell lines exhibit differential mitochondrial repair deficiency in response to 4NQO. | Oral oncology 20060201 |
| A speed congenic rat strain bearing the tongue cancer susceptibility locus Tscc1 from Dark-Agouti rats. | Cancer letters 20060118 |
| Mutagenesis. | Methods in molecular biology (Clifton, N.J.) 20060101 |
| Genotoxicity of dental resin polymerization initiators in vitro. | Journal of materials science. Materials in medicine 20060101 |
| [Cellular mechanisms of induction of apoptosis in human erythroleukaemic K562 cells line treated by quinoline-N-oxide derivatives]. | Biomeditsinskaia khimiia 20060101 |
| Expression of receptor for advanced glycation end products during rat tongue carcinogenesis by 4-nitroquinoline 1-oxide and effect of a selective cyclooxygenase-2 inhibitor, etodolac. | Pathobiology : journal of immunopathology, molecular and cellular biology 20060101 |
| Abnormal expression of bcl-2 and bax in rat tongue mucosa during the development of squamous cell carcinoma induced by 4-nitroquinoline 1-oxide. | International journal of experimental pathology 20051201 |
| Saccharomyces cerevisiae RAD53 (CHK2) but not CHK1 is required for double-strand break-initiated SCE and DNA damage-associated SCE after exposure to X rays and chemical agents. | DNA repair 20051121 |
| Studying the synergistic damage effects induced by 1.8 GHz radiofrequency field radiation (RFR) with four chemical mutagens on human lymphocyte DNA using comet assay in vitro. | Mutation research 20051015 |
| Modulation of gene expression in precancerous rat esophagus by dietary zinc deficit and replenishment. | Cancer research 20050901 |
| The role of trivalent dimethylated arsenic in dimethylarsinic acid-promoted skin and lung tumorigenesis in mice: tumor-promoting action through the induction of oxidative stress. | Toxicology letters 20050814 |
| Genome-wide requirements for resistance to functionally distinct DNA-damaging agents. | PLoS genetics 20050801 |
| Gene expression responses to DNA damage are altered in human aging and in Werner Syndrome. | Oncogene 20050728 |
| Screening of potential lactobacilli antigenotoxicity by microbial and mammalian cell-based tests. | International journal of food microbiology 20050625 |
| [Modulation of Chinese prescription Shenyang on Th1/Th2 cytokines in serum of SD rats with squamous cell carcinoma of the tongue]. | Shanghai kou qiang yi xue = Shanghai journal of stomatology 20050601 |
| [Influence of 1.8 GHz microwave on DNA damage induced by 4 chemical mutagens]. | Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20050601 |
| Chemoprevention of 4-NQO-induced oral carcinogenesis by co-administration of all-trans retinoic acid loaded microspheres and celecoxib. | Journal of controlled release : official journal of the Controlled Release Society 20050505 |
| Dietary garcinol inhibits 4-nitroquinoline 1-oxide-induced tongue carcinogenesis in rats. | Cancer letters 20050418 |
| Genotoxicity evaluation of electromagnetic fields generated by 835-MHz mobile phone frequency band. | European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20050401 |
| 4NQO oral carcinogenesis: animal models, molecular markers and future expectations. | Oral oncology 20050401 |
| Dynamics of glutathione conjugation and conjugate efflux in detoxification of the carcinogen, 4-nitroquinoline 1-oxide: contributions of glutathione, glutathione S-transferase, and MRP1. | Biochemistry 20050322 |
| [Modulation of Chinese regimen granules of Shenyang on peripheral blood lymphocyte subsets of SD rats with SCC of tongue]. | Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 20050301 |
| p53 protein activates the transcription of human proliferating cell nuclear antigen in response to 4-nitroquinoline N-oxide treatment. | The international journal of biochemistry & cell biology 20050201 |
| Dietary zinc modulation of COX-2 expression and lingual and esophageal carcinogenesis in rats. | Journal of the National Cancer Institute 20050105 |
| Genetic predisposition to 4NQO-induced tongue carcinogenesis in the rat. | Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20050101 |
| Differential regulation of gene expression by RNA polymerase II in response to DNA damage. | Biochemical and biophysical research communications 20041217 |
| Suppressive effects of a selective cyclooxygenase-2 inhibitor, etodolac, on 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20041201 |
| Antigenotoxic potential of glucomannan on four model test systems. | Cell biology and toxicology 20041101 |
| Therapeutic efficacy of green tea polyphenols on cellular thiols in 4-Nitroquinoline 1-oxide-induced oral carcinogenesis. | Chemico-biological interactions 20041015 |
| Hot spots for modulating toxicity identified by genomic phenotyping and localization mapping. | Molecular cell 20041008 |
| Genomic instability in non-neoplastic oral mucosa cells can predict risk during 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis. | Oral oncology 20041001 |
| Ectopic expression of tyrosinase increases melanin synthesis and cell death following UVB irradiation in fibroblasts from familial atypical multiple mole and melanoma (FAMMM) patients. | Melanoma research 20041001 |
| The yeast phosphotyrosyl phosphatase activator protein, yPtpa1/Rrd1, interacts with Sit4 phosphatase to mediate resistance to 4-nitroquinoline-1-oxide and UVA. | Current genetics 20040801 |
| High frequency methylation of p16INK4A gene during 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis. | Oncology reports 20040701 |
| The Werner syndrome protein confers resistance to the DNA lesions N3-methyladenine and O6-methylguanine: implications for WRN function. | DNA repair 20040603 |
| Effects of genotoxic compounds on DNA and development of early and late grass shrimp embryo stages. | Marine environmental research 20040601 |
| On the relevance of genotoxicity for fish populations I: effects of a model genotoxicant on zebrafish (Danio rerio) in a complete life-cycle test. | Aquatic toxicology (Amsterdam, Netherlands) 20040528 |
| On the relevance of genotoxicity for fish populations II: genotoxic effects in zebrafish (Danio rerio) exposed to 4-nitroquinoline-1-oxide in a complete life-cycle test. | Aquatic toxicology (Amsterdam, Netherlands) 20040528 |
| Genotoxicity of tamoxifen citrate and 4-nitroquinoline-1-oxide in the wing spot test of Drosophila melanogaster. | Mutagenesis 20040501 |
| Nitric oxide inhibits DNA-adduct excision in nucleotide excision repair. | Free radical biology & medicine 20040415 |
| Yeast MPH1 gene functions in an error-free DNA damage bypass pathway that requires genes from Homologous recombination, but not from postreplicative repair. | Genetics 20040401 |
| Enhanced stimulation of chromosomal translocations by radiomimetic DNA damaging agents and camptothecin in Saccharomyces cerevisiae rad9 checkpoint mutants. | Mutation research 20040322 |
| Interaction between the immune system and tongue squamous cell carcinoma induced by 4-nitroquinoline N-oxide in mice. | Oral oncology 20040301 |
| The Neurospora crassa mus-19 gene is identical to the qde-3 gene, which encodes a RecQ homologue and is involved in recombination repair and postreplication repair. | Current genetics 20040201 |
| Investigation of the antimutagenic effects of selected South African medicinal plant extracts. | Toxicology in vitro : an international journal published in association with BIBRA 20040201 |
| Expressions of junB and c-fos are enhanced in 4-nitroquinoline 1-oxide-induced rat tongue cancers. | Pathology international 20040101 |
| A p53-independent pathway regulates nucleolar segregation and antigen translocation in response to DNA damage induced by UV irradiation. | Experimental cell research 20040101 |
| Oral cavity and esophageal carcinogenesis modeled in carcinogen-treated mice. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040101 |
| Anti-stress activity of Propionibacterium freudenreichii : identification of a reactivative protein. | Antonie van Leeuwenhoek 20040101 |
| Apple phytochemicals and their health benefits. | Nutrition journal 20040101 |
| Transgenerational transmission of radiation- and chemically induced tumors and congenital anomalies in mice: studies of their possible relationship to induced chromosomal and molecular changes. | Cytogenetic and genome research 20040101 |
| Development of a genotoxicity detection system using a biosensor. | Environmental sciences : an international journal of environmental physiology and toxicology 20040101 |
| The protective effect of mild hyperthermia against UV-mimetic agent 4-nitroquinoline-1-oxide (4NQO) in human colon cells. | Research communications in molecular pathology and pharmacology 20040101 |
| p53 haploinsufficiency profoundly accelerates the onset of tongue tumors in mice lacking the xeroderma pigmentosum group A gene. | The American journal of pathology 20031101 |
| Changing expression of E- and P-cadherin during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide. | Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20031001 |
| Recombinogenic effects of DNA-damaging agents are synergistically increased by transcription in Saccharomyces cerevisiae. New insights into transcription-associated recombination. | Genetics 20031001 |
| Inhibitory effects of selective cyclooxygenase-2 inhibitors, nimesulide and etodolac, on the development of squamous cell dysplasias and carcinomas of the tongue in rats initiated with 4-nitroquinoline 1-oxide. | Cancer letters 20030925 |
| Expression of phosphorylated histone H2AX as a surrogate of cell killing by drugs that create DNA double-strand breaks. | Cancer research 20030801 |
| [Heat shock inhibits the induced expression of the SOS genes and SoxRS regulons in Escherichia coli]. | Genetika 20030801 |
| Histomorphologic and morphometric changes in minor salivary glands of the rat tongue during 4-nitroquinoline-1-oxide-induced carcinogenesis. | Oral oncology 20030701 |
| Correlation of P-cadherin and beta-catenin expression and phosphorylation with carcinogenesis in rat tongue cancer induced with 4-nitroquinoline 1-oxide. | Oral oncology 20030701 |
| The Schizosaccharomyces pombe cdt2(+) gene, a target of G1-S phase-specific transcription factor complex DSC1, is required for mitotic and premeiotic DNA replication. | Genetics 20030701 |
| Use of HepG2 cell line for direct or indirect mutagens screening: comparative investigation between comet and micronucleus assays. | Mutation research 20030420 |
| Inhibitory effects of troglitazone, a peroxisome proliferator-activated receptor gamma ligand, in rat tongue carcinogenesis initiated with 4-nitroquinoline 1-oxide. | Cancer science 20030401 |
| Modulation of mutagenicity of various mutagens by lignin derivatives. | Mutation research 20030303 |
| Antimutagenic activity of extracts of natural substances in the Salmonella/microsome assay. | Mutagenesis 20030301 |
| Mutagenicity of the oral carcinogen 4-nitroquinoline-1-oxide in cultured BigBlue rat tongue epithelial cells and fibroblasts. | Mutation research 20030128 |
| A COX-2 inhibitor, nimesulide, inhibits chemically-induced rat tongue carcinogenesis through suppression of cell proliferation activity and COX-2 and iNOS expression. | Histology and histopathology 20030101 |
| A novel geranylated derivative, ethyl 3-(4'-geranyloxy-3'-methoxyphenyl)-2-propenoate, synthesized from ferulic acid suppresses carcinogenesis and inducible nitric oxide synthase in rat tongue. | Oncology 20030101 |
| Antimutagenic effects of doenjang (Korean fermented soypaste) and its active compounds. | Mutation research 20030101 |
| [Erythroid differentiation of K562 cells resistant to 2-(4'-dimethylaminostyryl)quinoline 1-oxide or 4-nitroquinoline 1-oxide is significantly increased after thymidine treatment]. | Izvestiia Akademii nauk. Seriia biologicheskaia 20030101 |
| A yeast-based method for the detection of cyto and genotoxicity. | Toxicology in vitro : an international journal published in association with BIBRA 20030101 |
| Dietary protocatechuic acid during the progression phase exerts chemopreventive effects on chemically induced rat tongue carcinogenesis. | Asian Pacific journal of cancer prevention : APJCP 20030101 |
| Carcinogenesis modifier loci in rat tongue are subject to frequent loss of heterozygosity. | International journal of cancer 20021220 |
| Association of p16(INK4a) and pRb inactivation with immortalization of human cells. | Carcinogenesis 20021201 |
| Expression of beta-catenin in rat oral epithelial dysplasia induced by 4-nitroquinoline 1-oxide. | Oral oncology 20021201 |
| Lactic acid bacteria isolated from dairy products inhibit genotoxic effect of 4-nitroquinoline-1-oxide in SOS-chromotest. | Systematic and applied microbiology 20021201 |
| Colocalization of human Rad17 and PCNA in late S phase of the cell cycle upon replication block. | Oncogene 20021031 |
| Skeletal muscle regeneration associated with the stroma reaction during tumor invasion in the rat tongue. | Journal of submicroscopic cytology and pathology 20021001 |
| Chromosomal instability in B-lymphoblasotoid cell lines from Werner and Bloom syndrome patients. | Mutation research 20020926 |
| Genotoxicity is modulated by ascorbic acid. Studies using the wing spot test in Drosophila. | Mutation research 20020926 |
| Investigation of environmental factors for diagnosing malignant potential in oral epithelial dysplasia. | Oral oncology 20020901 |
| Modifying effects of dietary capsaicin and rotenone on 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis. | Carcinogenesis 20020801 |
| Effects of 1,4-phenylenebis(methylene)selenocyanate (p-XSC) and vitamin E on 4-nitroquinoline-N-oxide (4-NQO)-induced mutagenesis in lacZ mouse upper aerodigestive tissue. | Mutation research 20020627 |
| Measurement of DNA damage induced by irradiation with gamma-rays from a TRIGA Mark II research reactor in human cells using Fast Micromethod. | Cellular and molecular biology (Noisy-le-Grand, France) 20020601 |
| Werner syndrome diploid fibroblasts are sensitive to 4-nitroquinoline-N-oxide and 8-methoxypsoralen: implications for the disease phenotype. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020501 |
| Dietary silymarin suppresses 4-nitroquinoline 1-oxide-induced tongue carcinogenesis in male F344 rats. | Carcinogenesis 20020501 |
| A novel flow cytometric technique for drug cytotoxicity gives results comparable to colony-forming assays. | Cytometry 20020501 |
| Salmonella typhimurium mutagenicity tester strains that overexpress oxygen-insensitive nitroreductases nfsA and nfsB. | Mutation research 20020425 |
| Inhibition of 4-nitroquinoline-1-oxide genotoxicity by Bacillus strains. | Research in microbiology 20020401 |
| [Modification of repair DNA synthesis in mutagen-treated human fibroblasts during adaptive response and the antimutagenic effect of garlic extract]. | Genetika 20020301 |
| [Comparison of the protective effect of garlic extract and cell defense during adaptive response]. | Genetika 20020301 |
| Werner and Bloom helicases are involved in DNA repair in a complementary fashion. | Oncogene 20020131 |
| Phenotypic consequences of mutations in the conserved motifs of the putative helicase domain of the human Cockayne syndrome group B gene. | Gene 20020123 |
| Further evaluation of an in vivo micronucleus test on rat and mouse skin: results with five skin carcinogens. | Mutation research 20020115 |
| DNA damage and repair in lymphoblastoid cell lines from normal donors and fragile X syndrome patients. | Archives of medical research 20020101 |
| In vitro protective effects of Terminalia arjuna bark extracts against the 4-nitroquinoline-N-oxide genotoxicity. | Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20020101 |
| A novel nucleolar biomarker in plant and animal cells for assessment of substance cytotoxicity. | Environmental toxicology 20020101 |
| Antimutagenic activity of crown-containing compounds. | Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20020101 |
| PCNA in palate and tongue mucosal dysplastic lesions induced by topically applied 4NQO in desalivated rat. | Medicina oral : organo oficial de la Sociedad Espanola de Medicina Oral y de la Academia Iberoamericana de Patologia y Medicina Bucal 20020101 |
| Effects of long-term administration of cancer-promoting substances on oral subepithelial mast cells in the rat. | Anticancer research 20020101 |
| Oral mucosal carcinogenesis in SENCAR mice. | Anticancer research 20020101 |
| Different mutation status of the beta-catenin gene in carcinogen-induced colon, brain, and oral tumors in rats. | Molecular carcinogenesis 20011201 |
| Alteration of pRb expression in the development of rat tongue carcinoma induced by 4-nitroquinoline 1-oxide. | Oral oncology 20011001 |
| Roles of chromosomal and episomal dinB genes encoding DNA pol IV in targeted and untargeted mutagenesis in Escherichia coli. | Molecular genetics and genomics : MGG 20011001 |
| CaALK8, an alkane assimilating cytochrome P450, confers multidrug resistance when expressed in a hypersensitive strain of Candida albicans. | Yeast (Chichester, England) 20010915 |
| Activation of the Escherichia coli SoxRS-regulon by nitric oxide and its physiological donors. | Biochemistry. Biokhimiia 20010901 |
| The DNA helicase activity of yeast Sgs1p is essential for normal lifespan but not for resistance to topoisomerase inhibitors. | Mechanisms of ageing and development 20010801 |
| Epithelial-mesenchymal interactions in experimental oral mucosal carcinogenesis. | Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20010801 |
| Identification of genotoxic stress in human cells by fluorescent monitoring of p53 expression. | Mutation research 20010725 |
| Evaluation of the capacity of the SCGE assay to assess the genotoxicity of biomaterials. | Biomaterials 20010701 |
| Importance of DNA repair in carcinogenesis: evidence from transgenic and gene targeting studies. | Mutation research 20010602 |
| Evaluation of the toxicity of chemical compounds using digestive acini of the bivalve mollusc Pecten maximus L. maintained alive in vitro. | Aquatic toxicology (Amsterdam, Netherlands) 20010601 |
| Calcium is a key signaling molecule in beta-lapachone-mediated cell death. | The Journal of biological chemistry 20010601 |
| Five quantitative trait loci affecting 4-nitroquinoline 1-oxide-induced tongue cancer in the rat. | Japanese journal of cancer research : Gann 20010601 |
| Prevention of 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis by garlic. | Fitoterapia 20010601 |
| Ethidium bromide and SYBR Green I enhance the genotoxicity of UV-irradiation and chemical mutagens in E. coli. | Mutation research 20010531 |
| High-performance liquid chromatography--ToxPrint: chromatographic analysis with a novel (geno)toxicity detection. | Journal of chromatography. A 20010525 |
| A p53 dose-response relationship for sensitivity to DNA damage in isogenic teratocarcinoma cells. | Oncogene 20010524 |
| Werner helicase relocates into nuclear foci in response to DNA damaging agents and co-localizes with RPA and Rad51. | Genes to cells : devoted to molecular & cellular mechanisms 20010501 |
| Xeroderma pigmentosum group A gene action as a protection factor against 4-nitroquinoline 1-oxide-induced tongue carcinogenesis. | Carcinogenesis 20010401 |
| Bloom helicase is involved in DNA surveillance in early S phase in vertebrate cells. | Oncogene 20010308 |
| Activation of Ty transposition by mutagens. | Mutation research 20010301 |
| Overexpression of JunB in undifferentiated malignant rat oral keratinocytes enhances the malignant phenotype in vitro without altering cellular differentiation. | International journal of cancer 20010301 |
| [Ultramicrostructural observation on epithelial cell disdifferentiation in rat tongue carcinogenesis induced by 4NQO]. | Shanghai kou qiang yi xue = Shanghai journal of stomatology 20010301 |
| Increased expression of cyclooxygenase-2 protein in 4-nitroquinoline-1-oxide-induced rat tongue carcinomas and chemopreventive efficacy of a specific inhibitor, nimesulide. | Cancer research 20010215 |
| The effect of desalivation on 4-nitroquinoline-1-oxide-induced tongue carcinogenesis: a morphometric study of nucleolar organizer regions. | Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20010101 |
| Antimutagenic activity of isoflavone from Pueraria lobata. | Journal of agricultural and food chemistry 20010101 |
| Identification of a phosphoprotein that is downregulated in immortalized human fibroblasts. | Electrophoresis 20010101 |
| Effect of caffeine on the genotoxic effects of gamma radiation and 4-NQO in diploid yeast. | Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20010101 |
| [Extracellular protein of propionic acid bacteria inhibits induced mutation in strains of Salmonella typhimurium]. | Mikrobiologiia 20010101 |
| Roles of DT diaphorase in the genotoxicity of nitroaromatic compounds in human and fish cell lines. | Journal of toxicology and environmental health 19971010 |
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