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CAS No: 55-18-5 Catalog No: AG003T8Y MDL No:MFCD00013890
Title | Journal |
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Perindopril, fosinopril and losartan inhibited the progression of diethylnitrosamine-induced hepatocellular carcinoma in mice via the inactivation of nuclear transcription factor kappa-B. | Toxicology letters 20181001 |
Novel miRNA biomarkers for genotoxicity screening in mouse. | Toxicology 20180701 |
Altered cytokine profile under control of the serotonergic system determines the regulation of CYP2C11 and CYP3A isoforms. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20180601 |
Downregulation of metabotropic glutamate receptor 5 inhibits hepatoma development in a neurotoxin rotenone-induced Parkinson's disease model. | Toxicology letters 20180515 |
An integrative analysis of chemically-induced cirrhosis-associated hepatocarcinogenesis: Histological, biochemical and molecular features. | Toxicology letters 20171105 |
Nelumbo nucifera leaf extract treatment attenuated preneoplastic lesions and oxidative stress in the livers of diethylnitrosamine-treated rats. | Environmental toxicology 20171101 |
Downregulation of UBE2E2 in rat liver cells after hepatocarcinogen treatment facilitates cell proliferation and slowing down of DNA damage response in GST-P-expressing preneoplastic lesions. | Toxicology and applied pharmacology 20171101 |
Hesperidin protects against chemically induced hepatocarcinogenesis via modulation of Nrf2/ARE/HO-1, PPARγ and TGF-β1/Smad3 signaling, and amelioration of oxidative stress and inflammation. | Chemico-biological interactions 20171101 |
Vitamin D(3) supplementation attenuates the early stage of mouse hepatocarcinogenesis promoted by hexachlorobenzene fungicide. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20170901 |
Downregulation of TMEM70 in Rat Liver Cells After Hepatocarcinogen Treatment Related to the Warburg Effect in Hepatocarcinogenesis Producing GST-P-Expressing Proliferative Lesions. | Toxicological sciences : an official journal of the Society of Toxicology 20170901 |
Novel 1,2,4-triazole derivatives as antitumor agents against hepatocellular carcinoma. | Chemico-biological interactions 20170825 |
Targeting hepatocellular carcinoma with piperine by radical-mediated mitochondrial pathway of apoptosis: An in vitro and in vivo study. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20170701 |
Commiphora molmol resin attenuates diethylnitrosamine/phenobarbital-induced hepatocarcinogenesis by modulating oxidative stress, inflammation, angiogenesis and Nrf2/ARE/HO-1 signaling. | Chemico-biological interactions 20170525 |
Janus Kinase 2 (JAK2) Dissociates Hepatosteatosis from Hepatocellular Carcinoma in Mice. | The Journal of biological chemistry 20170303 |
Effect of resveratrol analogue, DMU-212, on antioxidant status and apoptosis-related genes in rat model of hepatocarcinogenesis. | Human & experimental toxicology 20170201 |
Identification of epigenetically downregulated Tmem70 and Ube2e2 in rat liver after 28-day treatment with hepatocarcinogenic thioacetamide showing gene product downregulation in hepatocellular preneoplastic and neoplastic lesions produced by tumor promotion. | Toxicology letters 20170115 |
Evaluation of cytotoxicity of a purified venom protein from Naja kaouthia (NKCT1) using gold nanoparticles for targeted delivery to cancer cell. | Chemico-biological interactions 20170105 |
Influence of sex and developmental stage on acute hepatotoxic and inflammatory responses to liver procarcinogens in the mouse. | Toxicology 20161212 |
Alternative Multiorgan Initiation-Promotion Assay for Chemical Carcinogenesis in the Wistar Rat. | Toxicologic pathology 20161201 |
The novel c-Met inhibitor capmatinib mitigates diethylnitrosamine acute liver injury in mice. | Toxicology letters 20161102 |
The impact of serotonergic system dysfunction on the regulation of P4501A isoforms during liver insufficiency and consequences for thyroid hormone homeostasis. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20161101 |
Bile acids promote diethylnitrosamine-induced hepatocellular carcinoma via increased inflammatory signaling. | American journal of physiology. Gastrointestinal and liver physiology 20160701 |
Involvement of Mouse Constitutive Androstane Receptor in Acifluorfen-Induced Liver Injury and Subsequent Tumor Development. | Toxicological sciences : an official journal of the Society of Toxicology 20160601 |
Tea polyphenols EGCG and TF restrict tongue and liver carcinogenesis simultaneously induced by N-nitrosodiethylamine in mice. | Toxicology and applied pharmacology 20160601 |
Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices. | Chemical research in toxicology 20160321 |
Characterization of copy number alterations in a mouse model of fibrosis-associated hepatocellular carcinoma reveals concordance with human disease. | Cancer medicine 20160301 |
Double staining of β-galactosidase with fibrosis and cancer markers reveals the chronological appearance of senescence in liver carcinogenesis induced by diethylnitrosamine. | Toxicology letters 20160122 |
A crucial role of constitutive androstane receptor (CAR) in liver tumor development by imazalil in mice. | The Journal of toxicological sciences 20160101 |
Hexachlorobenzene induces cell proliferation, and aryl hydrocarbon receptor expression (AhR) in rat liver preneoplastic foci, and in the human hepatoma cell line HepG2. AhR is a mediator of ERK1/2 signaling, and cell cycle regulation in HCB-treated HepG2 cells. | Toxicology 20151002 |
Essential role of constitutive androstane receptor in Ginkgo biloba extract induced liver hypertrophy and hepatocarcinogenesis. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20150901 |
Involvement of constitutive androstane receptor in liver hypertrophy and liver tumor development induced by triazole fungicides. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20150401 |
Farnesoid X receptor antagonizes JNK signaling pathway in liver carcinogenesis by activating SOD3. | Molecular endocrinology (Baltimore, Md.) 20150201 |
Gene expression of IQGAPs and Ras families in an experimental mouse model for hepatocellular carcinoma: a mechanistic study of cancer progression. | International journal of clinical and experimental pathology 20150101 |
Promoter-region hypermethylation and expression downregulation of Yy1 (Yin yang 1) in preneoplastic liver lesions in a thioacetamide rat hepatocarcinogenesis model. | Toxicology and applied pharmacology 20141101 |
Verapamil and rifampin effect on p-glycoprotein expression in hepatocellular carcinoma. | Jundishapur journal of natural pharmaceutical products 20141101 |
Comparative gene and protein expression analyses of a panel of cytokines in acute and chronic drug-induced liver injury in rats. | Toxicology 20141003 |
Ha-ras and β-catenin oncoproteins orchestrate metabolic programs in mouse liver tumors. | International journal of cancer 20141001 |
Formylchromone exhibits salubrious effects against nitrosodiethylamine mediated early hepatocellular carcinogenesis in rats. | Chemico-biological interactions 20140805 |
Liver tumor promotion by 2,3,7,8-tetrachlorodibenzo-p-dioxin is dependent on the aryl hydrocarbon receptor and TNF/IL-1 receptors. | Toxicological sciences : an official journal of the Society of Toxicology 20140701 |
Possible role of selective, irreversible, proteasome inhibitor (carfilzomib) in the treatment of rat hepatocellular carcinoma. | Chemico-biological interactions 20140525 |
Prevention of rat liver fibrosis and carcinogenesis by coffee and caffeine. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20140201 |
Modifying effects of liver tumor promotion in rats subjected to co-administration of indole-3-carbinol and phenobarbital. | The Journal of toxicological sciences 20140201 |
Chemoprevention by lipid-soluble tea polyphenols in diethylnitrosamine/phenobarbital-induced hepatic pre-cancerous lesions. | Anticancer research 20140201 |
Genomic models of short-term exposure accurately predict long-term chemical carcinogenicity and identify putative mechanisms of action. | PloS one 20140101 |
Detection of initiating potential of non-genotoxic carcinogens in a two-stage hepatocarcinogenesis study in rats. | The Journal of toxicological sciences 20140101 |
Chemically induced mouse liver tumors are resistant to treatment with atorvastatin. | BMC cancer 20140101 |
Comprehensive analysis of DNA methylation and gene expression of rat liver in a 2-stage hepatocarcinogenesis model. | The Journal of toxicological sciences 20140101 |
Anticarcinogenic effect of brucine in diethylnitrosamine initiated and phenobarbital-promoted hepatocarcinogenesis in rats. | Chemico-biological interactions 20131125 |
Lycopene modulates initiation of N-nitrosodiethylamine induced hepatocarcinogenesis: studies on chromosomal abnormalities, membrane fluidity and antioxidant defense system. | Chemico-biological interactions 20131125 |
Diphenylarsinic acid, a chemical warfare-related neurotoxicant, promotes liver carcinogenesis via activation of aryl hydrocarbon receptor signaling and consequent induction of oxidative DNA damage in rats. | Toxicology and applied pharmacology 20131115 |
Thymoquinone inhibits cell proliferation through regulation of G1/S phase cell cycle transition in N-nitrosodiethylamine-induced experimental rat hepatocellular carcinoma. | Toxicology letters 20131023 |
Global DNA methylation screening of liver in piperonyl butoxide-treated mice in a two-stage hepatocarcinogenesis model. | Toxicology letters 20131009 |
Inhibitory effect of α-lipoic acid on thioacetamide-induced tumor promotion through suppression of inflammatory cell responses in a two-stage hepatocarcinogenesis model in rats. | Chemico-biological interactions 20130925 |
Myrtenal ameliorates diethylnitrosamine-induced hepatocarcinogenesis through the activation of tumor suppressor protein p53 and regulation of lysosomal and mitochondrial enzymes. | Fundamental & clinical pharmacology 20130801 |
Diosmin abrogates chemically induced hepatocarcinogenesis via alleviation of oxidative stress, hyperproliferative and inflammatory markers in murine model. | Toxicology letters 20130718 |
Hepatocyte nuclear factor 4 alpha deletion promotes diethylnitrosamine-induced hepatocellular carcinoma in rodents. | Hepatology (Baltimore, Md.) 20130601 |
Matrix metalloproteinase Mmp-1a is dispensable for normal growth and fertility in mice and promotes lung cancer progression by modulating inflammatory responses. | The Journal of biological chemistry 20130517 |
Biological and tumor-promoting effects of dioxin-like and non-dioxin-like polychlorinated biphenyls in mouse liver after single or combined treatment. | Toxicological sciences : an official journal of the Society of Toxicology 20130501 |
Effect of enzymatically modified isoquercitrin on preneoplastic liver cell lesions induced by thioacetamide promotion in a two-stage hepatocarcinogenesis model using rats. | Toxicology 20130308 |
Molecular mechanisms of fibrosis-associated promotion of liver carcinogenesis. | Toxicological sciences : an official journal of the Society of Toxicology 20130301 |
Chrysin suppresses renal carcinogenesis via amelioration of hyperproliferation, oxidative stress and inflammation: plausible role of NF-κB. | Toxicology letters 20130204 |
Garlic oil attenuated nitrosodiethylamine-induced hepatocarcinogenesis by modulating the metabolic activation and detoxification enzymes. | International journal of biological sciences 20130101 |
Different pathways of constitutive androstane receptor-mediated liver hypertrophy and hepatocarcinogenesis in mice treated with piperonyl butoxide or decabromodiphenyl ether. | Toxicologic pathology 20130101 |
Liver tumor promoting effect of orphenadrine in rats and its possible mechanism of action including CAR activation and oxidative stress. | The Journal of toxicological sciences 20130101 |
Enhanced liver tumor promotion activity in rats subjected to combined administration of phenobarbital and orphenadrine. | The Journal of toxicological sciences 20130101 |
Suppressive effect of liver tumor-promoting activities in rats subjected to combined administration of phenobarbital and piperonyl butoxide. | The Journal of toxicological sciences 20130101 |
Ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid inhibits hepatocellular carcinoma in vitro and in vivo via stabilizing IkBα. | Investigational new drugs 20121201 |
Gender differences in the liver micronucleus test in rats with partial hepatectomy. | Toxicology letters 20121115 |
Astrocyte elevated gene-1 promotes hepatocarcinogenesis: novel insights from a mouse model. | Hepatology (Baltimore, Md.) 20121101 |
Effect of two selenium sources on hepatocarcinogenesis and several angiogenic cytokines in diethylnitrosamine-induced hepatocarcinoma rats. | Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20121001 |
Enhanced hepatocarcinogenesis in mouse models and human hepatocellular carcinoma by coordinate KLF6 depletion and increased messenger RNA splicing. | Hepatology (Baltimore, Md.) 20121001 |
Antitumour activity of Lycium chinensis polysaccharides in liver cancer rats. | International journal of biological macromolecules 20121001 |
Profound impact of gut homeostasis on chemically-induced pro-tumorigenic inflammation and hepatocarcinogenesis in rats. | Journal of hepatology 20121001 |
Characterization of N-diethylnitrosamine-initiated and ferric nitrilotriacetate-promoted renal cell carcinoma experimental model and effect of a tamarind seed extract against acute nephrotoxicity and carcinogenesis. | Molecular and cellular biochemistry 20121001 |
Myrtenal, a natural monoterpene, down-regulates TNF-α expression and suppresses carcinogen-induced hepatocellular carcinoma in rats. | Molecular and cellular biochemistry 20121001 |
Rats deficient for p53 are susceptible to spontaneous and carcinogen-induced tumorigenesis. | Carcinogenesis 20121001 |
Disruptive cell cycle regulation involving epigenetic downregulation of Cdkn2a (p16(Ink4a)) in early-stage liver tumor-promotion facilitating liver cell regeneration in rats. | Toxicology 20120928 |
Development of a repeated-dose liver micronucleus assay using adult rats: an investigation of diethylnitrosamine and 2,4-diaminotoluene. | Mutation research 20120918 |
Occurrence of aromatic amines and N-nitrosamines in the different steps of a drinking water treatment plant. | Water research 20120915 |
Combination treatment with bortezomib and thiostrepton is effective against tumor formation in mouse models of DEN/PB-induced liver carcinogenesis. | Cell cycle (Georgetown, Tex.) 20120915 |
Potential chemoprevention of diethylnitrosamine-induced hepatocarcinogenesis in rats: myrrh (Commiphora molmol) vs. turmeric (Curcuma longa). | Acta histochemica 20120901 |
Liver tumorigenicity promoted by microRNA-221 in a mouse transgenic model. | Hepatology (Baltimore, Md.) 20120901 |
Molecular MR imaging of liver fibrosis: a feasibility study using rat and mouse models. | Journal of hepatology 20120901 |
Thioredoxin reductase 1 protects against chemically induced hepatocarcinogenesis via control of cellular redox homeostasis. | Carcinogenesis 20120901 |
Lack of Hepatocarcinogenicity of Combinations of Low Doses of 2-amino-3, 8-dimethylimidazo[4,5- f ]quinoxaline and Diethylnitrosamine in Rats: Indication for the Existence of a Threshold for Genotoxic Carcinogens. | Journal of toxicologic pathology 20120901 |
Structural and numerical chromosome aberration inducers in liver micronucleus test in rats with partial hepatectomy. | Mutation research 20120830 |
The proinflammatory myeloid cell receptor TREM-1 controls Kupffer cell activation and development of hepatocellular carcinoma. | Cancer research 20120815 |
Increased expression of chondroitin sulphate proteoglycans in rat hepatocellular carcinoma tissues. | World journal of gastroenterology 20120814 |
Chemopreventive effects of the dietary histone deacetylase inhibitor tributyrin alone or in combination with vitamin A during the promotion phase of rat hepatocarcinogenesis. | The Journal of nutritional biochemistry 20120801 |
The inhibitory effect of rapamycin on the oval cell response and development of preneoplastic foci in the rat. | Experimental and molecular pathology 20120801 |
Gene expression profiles reveal significant differences between rat liver cancer and liver regeneration. | Gene 20120801 |
Myrtenal attenuates diethylnitrosamine-induced hepatocellular carcinoma in rats by stabilizing intrinsic antioxidants and modulating apoptotic and anti-apoptotic cascades. | Cellular oncology (Dordrecht) 20120801 |
Chemopreventive evaluation of Tephrosia purpurea against N-nitrosodiethylamine-induced hepatocarcinogenesis in Wistar rats. | The Journal of pharmacy and pharmacology 20120801 |
Evaluation of chemopreventive effect of Fumaria indica against N-nitrosodiethylamine and CCl4-induced hepatocellular carcinoma in Wistar rats. | Asian Pacific journal of tropical medicine 20120801 |
6-shogaol-rich extract from ginger up-regulates the antioxidant defense systems in cells and mice. | Molecules (Basel, Switzerland) 20120704 |
Preventive effect of phytoglycoprotein (38 kDa) on expression of alpha-fetoprotein and matrix metalloproteinase-9 in diethylnitrosamine-treated ICR mice. | Drug and chemical toxicology 20120701 |
Effect of prolyl hydroxylase domain-2 haplodeficiency on the hepatocarcinogenesis in mice. | Journal of hepatology 20120701 |
SJSZ glycoprotein (38kDa) prevents thymus atrophy and enhances expression of IL-2 and IL-12 in diethylnitrosamine-induced hepatocarcinogenesis. | International immunopharmacology 20120701 |
Age-dependent carcinogenic susceptibility in rat liver is related to potential of gap junctional intercellular communication. | Toxicologic pathology 20120701 |
Liver-specific overexpression of matrix metalloproteinase 9 (MMP-9) in transgenic mice accelerates development of hepatocellular carcinoma. | Molecular carcinogenesis 20120601 |
Preventive effect of caffeine and curcumin on hepato-carcinogenesis in diethylnitrosamine-induced rats. | International journal of oncology 20120601 |
Cohesin-SA1 deficiency drives aneuploidy and tumourigenesis in mice due to impaired replication of telomeres. | The EMBO journal 20120502 |
Azadirachta indica exhibits chemopreventive action against hepatic cancer: Studies on associated histopathological and ultrastructural changes. | Microscopy research and technique 20120501 |
MicroRNA in cancer: new hopes for antineoplastic chemotherapy. | Upsala journal of medical sciences 20120501 |
Effect of paeonol on antioxidant and immune regulatory activity in hepatocellular carcinoma rats. | Molecules (Basel, Switzerland) 20120420 |
Chronic ethanol feeding accelerates hepatocellular carcinoma progression in a sex-dependent manner in a mouse model of hepatocarcinogenesis. | Alcoholism, clinical and experimental research 20120401 |
Antagonistic effects of selenium and lipid peroxides on growth control in early hepatocellular carcinoma. | Hepatology (Baltimore, Md.) 20120401 |
Mice deficient in glycerol-3-phosphate acyltransferase-1 have a reduced susceptibility to liver cancer. | Toxicologic pathology 20120401 |
Cancer prevention mediated by caffeic acid phenethyl ester involves cyp2b1/2 modulation in hepatocarcinogenesis. | Toxicologic pathology 20120401 |
Attenuation of constitutive DNA damage signaling by 1,25-dihydroxyvitamin D3. | Aging 20120401 |
Occurrence and source of nitrosamines and secondary amines in groundwater and its adjacent Jialu River basin, China. | Environmental science & technology 20120320 |
Nicotinamide inhibits the early stage of carcinogen-induced hepatocarcinogenesis in mice and suppresses human hepatocellular carcinoma cell growth. | Journal of cellular physiology 20120301 |
Activity of tumor necrosis factor-α blocked by phytoglycoprotein (38 kDa) at initiation stage in N-nitrosodiethylamine-induced ICR mice. | Molecular and cellular biochemistry 20120301 |
Mechanistic study on liver tumor promoting effects of flutamide in rats. | Archives of toxicology 20120301 |
Ameliorative effect of methanol extract of Rubia cordifolia in N-nitrosodiethylamine-induced hepatocellular carcinoma. | Pharmaceutical biology 20120301 |
Chemopreventive effect of saikosaponin-d on diethylinitrosamine-induced hepatocarcinogenesis: involvement of CCAAT/enhancer binding protein β and cyclooxygenase-2. | Molecular medicine reports 20120301 |
Quantitative analysis of the growth kinetics of chemically induced mouse liver tumors by magnetic resonance imaging. | Toxicological sciences : an official journal of the Society of Toxicology 20120301 |
Autologous bone marrow cell infusions suppress tumor initiation in hepatocarcinogenic mice with liver cirrhosis. | Journal of gastroenterology and hepatology 20120301 |
Targeted therapy for hepatocellular carcinoma: novel agents on the horizon. | Oncotarget 20120301 |
Nanocapsulated curcumin: oral chemopreventive formulation against diethylnitrosamine induced hepatocellular carcinoma in rat. | Chemico-biological interactions 20120205 |
Estrogen suppresses metastasis in rat hepatocellular carcinoma through decreasing interleukin-6 and hepatocyte growth factor expression. | Inflammation 20120201 |
2-Amino-3-methylimidazo[4,5-f]quinoline (IQ) promotes mouse hepatocarcinogenesis by activating transforming growth factor-β and Wnt/β-catenin signaling pathways. | Toxicological sciences : an official journal of the Society of Toxicology 20120201 |
Diethylnitrosamine-induced hepatocarcinogenesis is suppressed in lecithin:retinol acyltransferase-deficient mice primarily through retinoid actions immediately after carcinogen administration. | Carcinogenesis 20120201 |
[Investigation on the levels of carbon-, nitrogen-, iodine-containing disinfection by-products in a water plant in Jiangsu province, China]. | Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20120201 |
Adenovirus-expressed preS2 antibody inhibits hepatitis B virus infection and hepatic carcinogenesis. | World journal of gastroenterology 20120128 |
Pressurised hot water extraction followed by headspace solid-phase microextraction and gas chromatography-tandem mass spectrometry for the determination of N-nitrosamines in sewage sludge. | Talanta 20120115 |
Alteration of hepatic proinflammatory cytokines is involved in the resveratrol-mediated chemoprevention of chemically-induced hepatocarcinogenesis. | Current pharmaceutical biotechnology 20120101 |
Ab initio and DFT conformational study on N-nitrosodiethylamine, (C2H5)2N-N=O. | Journal of molecular modeling 20120101 |
CXCR7 is up-regulated in human and murine hepatocellular carcinoma and is specifically expressed by endothelial cells. | European journal of cancer (Oxford, England : 1990) 20120101 |
Potential preventive effect of carvacrol against diethylnitrosamine-induced hepatocellular carcinoma in rats. | Molecular and cellular biochemistry 20120101 |
Transforming growth factor-β-stimulated clone-22 is a negative-feedback regulator of Ras / Raf signaling: Implications for tumorigenesis. | Cancer science 20120101 |
Anticarcinogenic activity of nanoencapsulated quercetin in combating diethylnitrosamine-induced hepatocarcinoma in rats. | European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20120101 |
Cytoplasmic Forkhead box M1 (FoxM1) in esophageal squamous cell carcinoma significantly correlates with pathological disease stage. | World journal of surgery 20120101 |
PEDF effectively decreases VEGF to PEDF messenger RNA ratio of the inner edge of rat hepatocellular carcinoma induced by diethyl nitrosamine - an 'in vivo' study. | Hepato-gastroenterology 20120101 |
Chloroform Extract of Rasagenthi Mezhugu, a Siddha Formulation, as an Evidence-Based Complementary and Alternative Medicine for HPV-Positive Cervical Cancers. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
Cytokines as important playmakers of experimental hepatocarcinogenesis confounded by diabetes. | Annals of hepatology 20120101 |
Chemically-induced cancers do not originate from bone marrow-derived cells. | PloS one 20120101 |
Transcriptional activation of microRNA-34a by NF-kappa B in human esophageal cancer cells. | BMC molecular biology 20120101 |
PET/CT imaging of c-Myc transgenic mice identifies the genotoxic N-nitroso-diethylamine as carcinogen in a short-term cancer bioassay. | PloS one 20120101 |
Brain insulin resistance and deficiency as therapeutic targets in Alzheimer's disease. | Current Alzheimer research 20120101 |
Anxiolytic activity of methanol leaf extract of Achyranthes aspera Linn in mice using experimental models of anxiety. | Indian journal of pharmacology 20120101 |
Pravastatin inhibits cell proliferation and increased MAT1A expression in hepatocarcinoma cells and in vivo models. | Cancer cell international 20120101 |
A garlic derivative, S-allylcysteine (SAC), suppresses proliferation and metastasis of hepatocellular carcinoma. | PloS one 20120101 |
Protective effects of garlic oil on hepatocarcinoma induced by N-nitrosodiethylamine in rats. | International journal of biological sciences 20120101 |
Methylation of Wnt7a is modulated by DNMT1 and cigarette smoke condensate in non-small cell lung cancer. | PloS one 20120101 |
Antioxidant-induced stress. | International journal of molecular sciences 20120101 |
Emodin prevents intrahepatic fat accumulation, inflammation and redox status imbalance during diet-induced hepatosteatosis in rats. | International journal of molecular sciences 20120101 |
Igf1 expression in mouse model of liver carcinogenesis. | Doklady. Biochemistry and biophysics 20120101 |
Phyllanthus urinaria Induces Apoptosis in Human Osteosarcoma 143B Cells via Activation of Fas/FasL- and Mitochondria-Mediated Pathways. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
Low-dose Cd induces hepatic gene hypermethylation, along with the persistent reduction of cell death and increase of cell proliferation in rats and mice. | PloS one 20120101 |
Liver tumor promoting effect of etofenprox in rats and its possible mechanism of action. | The Journal of toxicological sciences 20120101 |
A novel antihepatitis drug, bicyclol, prevents liver carcinogenesis in diethylnitrosamine-initiated and phenobarbital-promoted mice tumor model. | Journal of biomedicine & biotechnology 20120101 |
Opium use and mortality in Golestan Cohort Study: prospective cohort study of 50,000 adults in Iran. | BMJ (Clinical research ed.) 20120101 |
Text mining for literature review and knowledge discovery in cancer risk assessment and research. | PloS one 20120101 |
Potential Antioxidant Role of Tridham in Managing Oxidative Stress against Aflatoxin-B(1)-Induced Experimental Hepatocellular Carcinoma. | International journal of hepatology 20120101 |
Growth inhibition of human gynecologic and colon cancer cells by Phyllanthus watsonii through apoptosis induction. | PloS one 20120101 |
Efficient enrichment of hepatic cancer stem-like cells from a primary rat HCC model via a density gradient centrifugation-centered method. | PloS one 20120101 |
Integrated Analysis Reveals hsa-miR-142 as a Representative of a Lymphocyte-Specific Gene Expression and Methylation Signature. | Cancer informatics 20120101 |
Hepatitis B virus alters the antioxidant system in transgenic mice and sensitizes hepatocytes to Fas signaling. | PloS one 20120101 |
Targeting FGFR4 inhibits hepatocellular carcinoma in preclinical mouse models. | PloS one 20120101 |
PCB 126 and other dioxin-like PCBs specifically suppress hepatic PEPCK expression via the aryl hydrocarbon receptor. | PloS one 20120101 |
Molecular mechanisms of liver injury and hepatocarcinogenesis: focusing on the role of stress-activated MAPK. | Pathology research international 20120101 |
Radiation, inflammation, and immune responses in cancer. | Frontiers in oncology 20120101 |
Liver tumor promoting effect of omeprazole in rats and its possible mechanism of action. | The Journal of toxicological sciences 20120101 |
Threshold dose of liver tumor promoting effect of β-naphthoflavone in rats. | The Journal of toxicological sciences 20120101 |
Circulating tumor cells measurements in hepatocellular carcinoma. | International journal of hepatology 20120101 |
β-Catenin loss in hepatocytes promotes hepatocellular cancer after diethylnitrosamine and phenobarbital administration to mice. | PloS one 20120101 |
Radio-deoxynucleoside Analogs used for Imaging tk Expression in a Transgenic Mouse Model of Induced Hepatocellular Carcinoma. | Theranostics 20120101 |
Effects of pinocembrin on the initiation and promotion stages of rat hepatocarcinogenesis. | Asian Pacific journal of cancer prevention : APJCP 20120101 |
Enhanced liver tumor promotion but not liver initiation activity in rats subjected to combined administration of omeprazole and β-naphthoflavone. | The Journal of toxicological sciences 20120101 |
Sewage sludge does not induce genotoxicity and carcinogenesis. | Genetics and molecular biology 20120101 |
Increased expression of epithelial cell adhesion molecule (EpCAM) in rat hepatic tumors induced by diethylnitrosamine. | Asian Pacific journal of cancer prevention : APJCP 20120101 |
Time-series analysis of gene expression profiles induced by nitrosamides and nitrosamines elucidates modes of action underlying their genotoxicity in human colon cells. | Toxicology letters 20111215 |
Autophagy enhanced by microtubule- and mitochondrion-associated MAP1S suppresses genome instability and hepatocarcinogenesis. | Cancer research 20111215 |
Correlation between liver cancer occurrence and gene expression profiles in rat liver tissue. | Genetics and molecular research : GMR 20111214 |
Identification of biomarkers of chemically induced hepatocarcinogenesis in rasH2 mice by toxicogenomic analysis. | Archives of toxicology 20111201 |
The effect of N-nitrosodimethylamine (NDMA) on Bax and Mcl-1 expression in human neutrophils. | Bulletin of environmental contamination and toxicology 20111201 |
Assessment of genotoxicity induced by 7,12-dimethylbenz(a)anthracene or diethylnitrosamine in the Pig-a, micronucleus and Comet assays integrated into 28-day repeat dose studies. | Environmental and molecular mutagenesis 20111201 |
Differential biodistribution of oncolytic poxvirus administered systemically in an autochthonous model of hepatocellular carcinoma. | The journal of gene medicine 20111201 |
Report on stage III Pig-a mutation assays using N-ethyl-N-nitrosourea-comparison with other in vivo genotoxicity endpoints. | Environmental and molecular mutagenesis 20111201 |
The protective effects of fish oil and artichoke on hepatocellular carcinoma in rats. | European review for medical and pharmacological sciences 20111201 |
Concordance between Results of Medium-term Liver Carcinogenesis Bioassays and Long-term Findings for Carcinogenic 2-Nitropropane and Non-carcinogenic1-Nitropropane in F344 Rats. | Journal of toxicologic pathology 20111201 |
The human lung adenocarcinoma cell line EKVX produces an infectious xenotropic murine leukemia virus. | Viruses 20111201 |
Selenium supplementation reduced oxidative stress in diethylnitrosamine-induced hepatocellular carcinoma in rats. | Pakistan journal of biological sciences : PJBS 20111201 |
Preclinical renal cancer chemopreventive efficacy of geraniol by modulation of multiple molecular pathways. | Toxicology 20111128 |
Medium-term multi-organ carcinogenesis bioassay of ethyl tertiary-butyl ether in rats. | Toxicology 20111118 |
Anthocyanin-rich black currant (Ribes nigrum L.) extract affords chemoprevention against diethylnitrosamine-induced hepatocellular carcinogenesis in rats. | The Journal of nutritional biochemistry 20111101 |
Expression of c-jun is not mandatory for mouse hepatocyte proliferation induced by two nuclear receptor ligands: TCPOBOP and T3. | Journal of hepatology 20111101 |
Suppressive effect of enzymatically modified isoquercitrin on phenobarbital-induced liver tumor promotion in rats. | Archives of toxicology 20111101 |
Folic acid supplementation during early hepatocarcinogenesis: cellular and molecular effects. | International journal of cancer 20111101 |
Non-invasive monitoring of hepatocellular carcinoma in transgenic mouse with bioluminescent imaging. | Cancer letters 20111101 |
Development and evaluation of a genomic signature for the prediction and mechanistic assessment of nongenotoxic hepatocarcinogens in the rat. | Toxicological sciences : an official journal of the Society of Toxicology 20111101 |
Effect of some naturally occurring iron ion chelators on the formation of radicals in the reaction mixtures of rat liver microsomes with ADP, Fe and NADPH. | Journal of clinical biochemistry and nutrition 20111101 |
[Studies on tea and health]. | Wei sheng yan jiu = Journal of hygiene research 20111101 |
Senescence marker protein 30 (SMP30)/regucalcin (RGN) expression decreases with aging, acute liver injuries and tumors in zebrafish. | Biochemical and biophysical research communications 20111022 |
Occurrence of nine nitrosamines and secondary amines in source water and drinking water: Potential of secondary amines as nitrosamine precursors. | Water research 20111015 |
N-Nitrosodiethylamine genotoxicity in primary rat hepatocytes: effects of cytochrome P450 induction by phenobarbital. | Toxicology letters 20111010 |
N-nitrosodiethylamine genotoxicity evaluation: a cytochrome P450 induction study in rat hepatocytes. | Genetics and molecular research : GMR 20111005 |
RB and p53 cooperate to prevent liver tumorigenesis in response to tissue damage. | Gastroenterology 20111001 |
PUMA-mediated apoptosis drives chemical hepatocarcinogenesis in mice. | Hepatology (Baltimore, Md.) 20111001 |
Biotransformation of nitrosamines and precursor secondary amines under methanogenic conditions. | Environmental science & technology 20111001 |
Effects of raspberry phytochemical extract on cell proliferation, apoptosis, and serum proteomics in a rat model. | Journal of food science 20111001 |
Determination of eight nitrosamines in water at the ng L(-1) levels by liquid chromatography coupled to atmospheric pressure chemical ionization tandem mass spectrometry. | Analytica chimica acta 20110919 |
c-Met-Akt pathway-mediated enhancement of inhibitory c-Raf phosphorylation is involved in vitamin K1 and sorafenib synergy on HCC growth inhibition. | Cancer biology & therapy 20110915 |
Saffron: a potential candidate for a novel anticancer drug against hepatocellular carcinoma. | Hepatology (Baltimore, Md.) 20110902 |
Relationship between CYP1A induction by indole-3-carbinol or flutamide and liver tumor-promoting potential in rats. | Archives of toxicology 20110901 |
Absence of hepatic stellate cell retinoid lipid droplets does not enhance hepatic fibrosis but decreases hepatic carcinogenesis. | Gut 20110901 |
Aberrant expression of the p53-inducible antiproliferative gene BTG2 in hepatocellular carcinoma is associated with overexpression of the cell cycle-related proteins. | Cell biochemistry and biophysics 20110901 |
miR-22 promotes HBV-related hepatocellular carcinoma development in males. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110901 |
Effect of N'-nitrosodimethylamine on red blood cell rheology and proteomic profiles of brain in male albino rats. | Interdisciplinary toxicology 20110901 |
Genetic and epigenetic alterations of lysophosphatidic Acid receptor genes in rodent tumors by experimental models. | Journal of toxicologic pathology 20110901 |
Methylated chrysin induces co-ordinated attenuation of the canonical Wnt and NF-kB signaling pathway and upregulates apoptotic gene expression in the early hepatocarcinogenesis rat model. | Chemico-biological interactions 20110815 |
Carcinogen-induced hepatic tumors in KLF6+/- mice recapitulate aggressive human hepatocellular carcinoma associated with p53 pathway deregulation. | Hepatology (Baltimore, Md.) 20110801 |
The role for estrogen receptor-alpha and prolactin receptor in sex-dependent DEN-induced liver tumorigenesis. | Carcinogenesis 20110801 |
Dose-related induction of hepatic preneoplastic lesions by diethylnitrosamine in C57BL/6 mice. | Toxicologic pathology 20110801 |
Promotion of liver and lung tumorigenesis in DEN-treated cytoglobin-deficient mice. | The American journal of pathology 20110801 |
Hepatoprotective versus oncogenic functions of STAT3 in liver tumorigenesis. | The American journal of pathology 20110801 |
Towards a system level understanding of non-model organisms sampled from the environment: a network biology approach. | PLoS computational biology 20110801 |
Alpha-fetoprotein-thymidine kinase-luciferase knockin mice: a novel model for dual modality longitudinal imaging of tumorigenesis in liver. | Journal of hepatology 20110701 |
Targeted deletion of GSNOR in hepatocytes of mice causes nitrosative inactivation of O6-alkylguanine-DNA alkyltransferase and increased sensitivity to genotoxic diethylnitrosamine. | Carcinogenesis 20110701 |
Effect of Aegle marmelos on DEN initiated and 2-AAF promoted hepatocarcinogenesis: a chemopreventive study. | Toxicology mechanisms and methods 20110701 |
A mouse model of cholestasis-associated cholangiocarcinoma and transcription factors involved in progression. | Gastroenterology 20110701 |
In vivo consequences of liver-specific interleukin-22 expression in mice: Implications for human liver disease progression. | Hepatology (Baltimore, Md.) 20110701 |
Apoptosis signal-regulating kinase 1 inhibits hepatocarcinogenesis by controlling the tumor-suppressing function of stress-activated mitogen-activated protein kinase. | Hepatology (Baltimore, Md.) 20110701 |
Genomic profiling uncovers a molecular pattern for toxicological characterization of mutagens and promutagens in vitro. | Toxicological sciences : an official journal of the Society of Toxicology 20110701 |
Protective effects of fermented rice vinegar sediment (Kurozu moromimatsu) in a diethylnitrosamine-induced hepatocellular carcinoma animal model. | Journal of clinical biochemistry and nutrition 20110701 |
Production of liver preneoplasia and gallbladder agenesis in turkey fetuses administered diethylnitrosamine. | Archives of toxicology 20110601 |
Pomegranate-mediated chemoprevention of experimental hepatocarcinogenesis involves Nrf2-regulated antioxidant mechanisms. | Carcinogenesis 20110601 |
Yes-associated protein regulation of adaptive liver enlargement and hepatocellular carcinoma development in mice. | Hepatology (Baltimore, Md.) 20110601 |
Suppressed liver tumorigenesis in fat-1 mice with elevated omega-3 fatty acids is associated with increased omega-3 derived lipid mediators and reduced TNF-α. | Carcinogenesis 20110601 |
Nuclear receptor CAR-regulated expression of the FAM84A gene during the development of mouse liver tumors. | International journal of oncology 20110601 |
Inhibitory effect of phytoglycoprotein (24 kDa) on hepatocarcinogenesis in N-nitrosodiethylamine-treated ICR mice. | The Journal of pharmacy and pharmacology 20110601 |
Urban, traffic- related particles and lung tumors in urethane treated mice. | Clinics (Sao Paulo, Brazil) 20110601 |
The effects of milk thistle on hepatic fibrosis due to methotrexate in rat. | Hepatitis monthly 20110601 |
Suppression of hepatic tumor growth and metastasis by metronomic therapy in a rat model of hepatocellular carcinoma. | Experimental & molecular medicine 20110531 |
Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis. | Cancer cell 20110517 |
Indole-3-carbinol enhances oxidative stress responses resulting in the induction of preneoplastic liver cell lesions in partially hepatectomized rats initiated with diethylnitrosamine. | Toxicology 20110510 |
Polyol profile as an early diagnostic and prognostic marker in natural product chemoprevention of hepatocellular carcinoma in diabetic rats. | Diabetes research and clinical practice 20110501 |
Assessing granular media filtration for the removal of chemical contaminants from wastewater. | Water research 20110501 |
Concomitant apoptosis and regeneration of liver cells as a mechanism of liver-tumor promotion by β-naphthoflavone involving TNFα-signaling due to oxidative cellular stress in rats. | Toxicology 20110428 |
Determination of volatile nitrosamines in meat products by microwave-assisted extraction and dispersive liquid-liquid microextraction coupled to gas chromatography-mass spectrometry. | Journal of chromatography. A 20110408 |
Determination of nitrosamines in water by gas chromatography/chemical ionization/selective ion trapping mass spectrometry. | Journal of chromatography. A 20110408 |
Chemopreventive doses of resveratrol do not produce cardiotoxicity in a rodent model of hepatocellular carcinoma. | Investigational new drugs 20110401 |
Constitutive active/androstane receptor promotes hepatocarcinogenesis in a mouse model of non-alcoholic steatohepatitis. | Carcinogenesis 20110401 |
Helicobacter hepaticus--induced liver tumor promotion is associated with increased serum bile acid and a persistent microbial-induced immune response. | Cancer research 20110401 |
Immunotherapy of hepatocellular carcinoma: is there a place for regulatory T-lymphocyte depletion? | Immunotherapy 20110401 |
Liver specific overexpression of platelet-derived growth factor-B accelerates liver cancer development in chemically induced liver carcinogenesis. | International journal of cancer 20110315 |
Protective effect of chokeberry on chemical-induced oxidative stress in rat. | Human & experimental toxicology 20110301 |
Transgenic mice expressing cyclooxygenase-2 in hepatocytes reveal a minor contribution of this enzyme to chemical hepatocarcinogenesis. | The American journal of pathology 20110301 |
Preventive effects of (-)-epigallocatechin gallate on diethylnitrosamine-induced liver tumorigenesis in obese and diabetic C57BL/KsJ-db/db Mice. | Cancer prevention research (Philadelphia, Pa.) 20110301 |
Of mice and men: the nonrandom genomic instability in hepatocarcinogenesis. | Hepatology (Baltimore, Md.) 20110301 |
Evolution of genomic instability in diethylnitrosamine-induced hepatocarcinogenesis in mice. | Hepatology (Baltimore, Md.) 20110301 |
Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health. | Oncotarget 20110301 |
Chemoprevention of hepatocellular carcinoma. Proof of concept in animal models. | Acta gastro-enterologica Belgica 20110301 |
Influence of CLOCK on cytotoxicity induced by diethylnitrosamine in mouse primary hepatocytes. | Toxicology 20110227 |
Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of DNA methyltransferases 1 and 3a. | Toxicology and applied pharmacology 20110215 |
Chrysin abrogates early hepatocarcinogenesis and induces apoptosis in N-nitrosodiethylamine-induced preneoplastic nodules in rats. | Toxicology and applied pharmacology 20110215 |
Cloudy apple juice protects against chemical-induced oxidative stress in rat. | European journal of nutrition 20110201 |
Immunohistochemical analyses at the late stage of tumor promotion by oxfendazole in a rat hepatocarcinogenesis model. | Archives of toxicology 20110201 |
(1)H-NMR-based metabolomics of tumor tissue for the metabolic characterization of rat hepatocellular carcinoma formation and metastasis. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20110201 |
Elevated expression of urotensin II and its receptor in diethylnitrosamine-mediated precancerous lesions in rat liver. | Peptides 20110201 |
Mutations and aberrant transcriptions of Stk11 (Lkb1) gene in rat liver tumors. | Anticancer research 20110201 |
Genotoxic evaluation of the non-halogenated disinfection by-products nitrosodimethylamine and nitrosodiethylamine. | Journal of hazardous materials 20110130 |
Circulating microRNAs, possible indicators of progress of rat hepatocarcinogenesis from early stages. | Toxicology letters 20110115 |
Antioxidant and hepatoprotective effects of silibinin in a rat model of nonalcoholic steatohepatitis. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
Ellagic Acid, the Active Compound of Phyllanthus urinaria, Exerts In Vivo Anti-Angiogenic Effect and Inhibits MMP-2 Activity. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
Mitochondrial prohibitins and septin 9 are implicated in the onset of rat hepatocarcinogenesis. | Toxicological sciences : an official journal of the Society of Toxicology 20110101 |
Methylated chrysin, a dimethoxy flavone, partially suppresses the development of liver preneoplastic lesions induced by N-nitrosodiethylamine in rats. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110101 |
AFP-specific immunotherapy impairs growth of autochthonous hepatocellular carcinoma in mice. | Journal of hepatology 20110101 |
Tumor formation in liver of conditional β-catenin-deficient mice exposed to a diethylnitrosamine/phenobarbital tumor promotion regimen. | Carcinogenesis 20110101 |
Acyclic retinoid inhibits diethylnitrosamine-induced liver tumorigenesis in obese and diabetic C57BLKS/J- +(db)/+Lepr(db) mice. | Cancer prevention research (Philadelphia, Pa.) 20110101 |
Dual induction of caspase 3- and transglutaminase-dependent apoptosis by acyclic retinoid in hepatocellular carcinoma cells. | Molecular cancer 20110101 |
Overexpression of histone variant H2A.1 and cellular transformation are related in N-nitrosodiethylamine-induced sequential hepatocarcinogenesis. | Experimental biology and medicine (Maywood, N.J.) 20110101 |
Tumor promoters--microcystin-LR, nodularin and TNF-α and human cancer development. | Anti-cancer agents in medicinal chemistry 20110101 |
Inhibitory effects of Indigofera aspalathoides on 20-methylcholanthrene-induced chemical carcinogenesis in rats. | Journal of carcinogenesis 20110101 |
Quercetin inhibits diethylnitrosamine-induced hepatic preneoplastic lesions in rats. | Nutrition and cancer 20110101 |
Role of cancer stem cells in hepatocarcinogenesis. | Genome medicine 20110101 |
A comparison and user-based evaluation of models of textual information structure in the context of cancer risk assessment. | BMC bioinformatics 20110101 |
Lipid nanocapsules loaded with rhenium-188 reduce tumor progression in a rat hepatocellular carcinoma model. | PloS one 20110101 |
Phenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice. | PloS one 20110101 |
Efficacy of mesenchymal stem cells in suppression of hepatocarcinorigenesis in rats: possible role of Wnt signaling. | Journal of experimental & clinical cancer research : CR 20110101 |
Phytochemical Analysis and Antioxidant Property of Leaf Extracts of Vitex doniana and Mucuna pruriens. | Biochemistry research international 20110101 |
Signal transducer and activator of transcription 3 in liver diseases: a novel therapeutic target. | International journal of biological sciences 20110101 |
Chemopreventive effect of hydroethanolic extract of Euphorbia neriifolia leaves against DENA-induced renal carcinogenesis in mice. | Asian Pacific journal of cancer prevention : APJCP 20110101 |
Evaluation of genetic damage induced by glyphosate isopropylamine salt using Tradescantia bioassays. | Genetics and molecular biology 20110101 |
Pitavastatin suppresses diethylnitrosamine-induced liver preneoplasms in male C57BL/KsJ-db/db obese mice. | BMC cancer 20110101 |
Evaluation of cytotoxicity and genotoxicity of some Philippine medicinal plants. | Pharmacognosy magazine 20110101 |
Targeting insulin-like growth factor axis in hepatocellular carcinoma. | Journal of hematology & oncology 20110101 |
Thyroid hormone receptor mutations in cancer and resistance to thyroid hormone: perspective and prognosis. | Journal of thyroid research 20110101 |
Emblica officinalis Gaertn. attentuates N-nitrosodiethylamine-induced apoptosis, autophagy, and inflammation in rat livers. | Journal of medicinal food 20110101 |
Short-term exposure to tobacco toxins alters expression of multiple proliferation gene markers in primary human bronchial epithelial cell cultures. | Journal of oncology 20110101 |
Quercetin and cancer chemoprevention. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
Herbal medicine and hepatocellular carcinoma: applications and challenges. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
5-Lipoxygenase contributes to the progression of hepatocellular carcinoma. | Molecular medicine reports 20110101 |
Resveratrol interferes with N-nitrosodiethylamine-induced hepatocellular carcinoma at early and advanced stages in male Wistar rats. | Molecular medicine reports 20110101 |
N-Nitrosamines (15 listings): N-Nitrosodiethanolamine. | Report on carcinogens : carcinogen profiles 20110101 |
N-Nitrosamines (15 listings): N-Nitrosodiethylamine. | Report on carcinogens : carcinogen profiles 20110101 |
Gene expression study using real-time PCR identifies an NTR gene as a major marker of resistance to benzonidazole in Trypanosoma cruzi. | Parasites & vectors 20110101 |
Association of HLA-B*5801 allele and allopurinol-induced Stevens Johnson syndrome and toxic epidermal necrolysis: a systematic review and meta-analysis. | BMC medical genetics 20110101 |
Absence of p53 gene expression in selenium molecular prevention of chemically induced hepatocarcinogenesis in rats. | Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20110101 |
[The most important stages of the mechanism of action in vivo of carcinogen diethylnitrosoamine and its effect on the synthesis of RNA, proteins, DNA, and deoxyribonucleotides]. | Biofizika 20110101 |
Experimental Hepatotoxicity Produced by Ethinyl estradiol. | Toxicology international 20110101 |
Dysregulation of gene expression in the artificial human trisomy cells of chromosome 8 associated with transformed cell phenotypes. | PloS one 20110101 |
Molecular targets and oxidative stress biomarkers in hepatocellular carcinoma: an overview. | Journal of translational medicine 20110101 |
Unique Properties of Hepatocarcinogenesis-Resistant DRH Rat Hepatocytes Linked or Not Linked to the Drh1 Locus on Rat Chromosome 1. | International journal of hepatology 20110101 |
Liver cancer stem cells. | International journal of hepatology 20110101 |
Humanizing π-class glutathione S-transferase regulation in a mouse model alters liver toxicity in response to acetaminophen overdose. | PloS one 20110101 |
Hepatocyte IKK2 protects Mdr2-/- mice from chronic liver failure. | PloS one 20110101 |
Azidothymidine treatment of hepatocellular carcinoma in rats: an in vivo study of telomerase inhibition. | Hepato-gastroenterology 20110101 |
The chemopreventive effect of Ginkgo biloba and Silybum marianum extracts on hepatocarcinogenesis in rats. | Cancer cell international 20110101 |
Effects of dietary fish oil on the depletion of carcinogenic PAH-DNA adduct levels in the liver of B6C3F1 mouse. | PloS one 20110101 |
Fungus-mediated biological synthesis of gold nanoparticles: potential in detection of liver cancer. | International journal of nanomedicine 20110101 |
Manganese superoxide dismutase: guardian of the powerhouse. | International journal of molecular sciences 20110101 |
Male germ cell-specific RNA binding protein RBMY: a new oncogene explaining male predominance in liver cancer. | PloS one 20110101 |
New short term prediction method for chemical carcinogenicity by hepatic transcript profiling following 28-day toxicity tests in rats. | Cancer informatics 20110101 |
Anti-inflammatory drugs reduce the risk of hepatocellular carcinoma development. | ISRN oncology 20110101 |
Cuminum cyminum and Carum carvi: An update. | Pharmacognosy reviews 20110101 |
Antioxidant N-acetyl-L-cysteine (NAC) supplementation reduces reactive oxygen species (ROS)-mediated hepatocellular tumor promotion of indole-3-carbinol (I3C) in rats. | The Journal of toxicological sciences 20110101 |
STAT3 activation in monocytes accelerates liver cancer progression. | BMC cancer 20110101 |
Transcriptome analysis of anti-fatty liver action by Campari tomato using a zebrafish diet-induced obesity model. | Nutrition & metabolism 20110101 |
Scientific basis for the therapeutic use of Cymbopogon citratus, stapf (Lemon grass). | Journal of advanced pharmaceutical technology & research 20110101 |
Cigarette smoke and cancer. | Journal of oncology 20110101 |
Protective effects of physiological doses of estrogen during hepatocarcinogenesis induced by diethylnitrosamine and N-nitrosomorpholine. | Hepato-gastroenterology 20110101 |
Anticancer effects of Huaier are associated with down-regulation of P53. | Asian Pacific journal of cancer prevention : APJCP 20110101 |
Loss of metallothionein predisposes mice to diethylnitrosamine-induced hepatocarcinogenesis by activating NF-kappaB target genes. | Cancer research 20101215 |
Dissection of DEN-induced platelet proteome changes reveals the progressively dys-regulated pathways indicative of hepatocarcinogenesis. | Journal of proteome research 20101203 |
Relationship between DNA damage and micronucleus in mouse liver. | The Journal of toxicological sciences 20101201 |
Ability of Allium cepa L. root tips and Tradescantia pallida var. purpurea in N-nitrosodiethylamine genotoxicity and mutagenicity evaluation. | Anais da Academia Brasileira de Ciencias 20101201 |
Amelioration effects against N-nitrosodiethylamine and CCl(4)-induced hepatocarcinogenesis in Swiss albino rats by whole plant extract of Achyranthes aspera. | Indian journal of pharmacology 20101201 |
CpG island hypermethylation of multiple tumor suppressor genes associated with loss of their protein expression during rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine. | Biochemical and biophysical research communications 20101119 |
The Salmonella mutagenicity assay: the stethoscope of genetic toxicology for the 21st century. | Environmental health perspectives 20101101 |
Genotoxic and carcinogenic risks associated with the dietary consumption of repeatedly heated coconut oil. | The British journal of nutrition 20101101 |
Determination of volatile nitrosamines in various meat products using comprehensive gas chromatography-nitrogen chemiluminescence detection. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20101101 |
Comparative chronic liver toxicity of benzo[a]pyrene in two populations of the atlantic killifish (Fundulus heteroclitus) with different exposure histories. | Environmental health perspectives 20101001 |
Endotoxin accumulation prevents carcinogen-induced apoptosis and promotes liver tumorigenesis in rodents. | Hepatology (Baltimore, Md.) 20101001 |
Preparation of 177Lu-labeled oxine in lipiodol as a possible agent for therapy of hepatocellular carcinoma: a preliminary animal study. | Cancer biotherapy & radiopharmaceuticals 20101001 |
Attenuation of N-nitrosodiethylamine-induced liver fibrosis by high-molecular-weight fucoidan derived from Cladosiphon okamuranus. | Journal of gastroenterology and hepatology 20101001 |
UVA activation of N-dialkylnitrosamines releasing nitric oxide, producing strand breaks as well as oxidative damages in DNA, and inducing mutations in the Ames test. | Mutation research 20100910 |
Alteration of N-glycome in diethylnitrosamine-induced hepatocellular carcinoma mice: a non-invasive monitoring tool for liver cancer. | Liver international : official journal of the International Association for the Study of the Liver 20100901 |
Conditional beta-catenin loss in mice promotes chemical hepatocarcinogenesis: role of oxidative stress and platelet-derived growth factor receptor alpha/phosphoinositide 3-kinase signaling. | Hepatology (Baltimore, Md.) 20100901 |
Gas chromatography/time-of-flight mass spectrometry-based metabonomics of hepatocarcinoma in rats with lung metastasis: elucidation of the metabolic characteristics of hepatocarcinoma at formation and metastasis. | Rapid communications in mass spectrometry : RCM 20100901 |
Mouse models of hepatocarcinogenesis: what can we learn for the prevention of human hepatocellular carcinoma? | Oncotarget 20100901 |
Promoting Effects of Streptozotocin-induced Diabetes on Induction of Hepatic Preneoplastic Lesions by Diethylnitrosamine in Rats. | Journal of toxicologic pathology 20100901 |
Potential chemoprevention of diethylnitrosamine-initiated and 2-acetylaminofluorene-promoted hepatocarcinogenesis by zerumbone from the rhizomes of the subtropical ginger (Zingiber zerumbet). | Chemico-biological interactions 20100805 |
Tea polyphenols inhibit cyclooxygenase-2 expression and block activation of nuclear factor-kappa B and Akt in diethylnitrosoamine induced lung tumors in Swiss mice. | Investigational new drugs 20100801 |
DNA instability at chromosomal fragile sites in cancer. | Current genomics 20100801 |
Comparison of N-nitrosodiethylamine degradation in water by UV irradiation and UV/O3: efficiency, product and mechanism. | Journal of hazardous materials 20100715 |
Absence of chemopreventive influence of propolis on the rat liver altered foci development. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20100701 |
Radical mechanisms in nitrosamine- and nitrosamide-induced whole-genome gene expression modulations in Caco-2 cells. | Toxicological sciences : an official journal of the Society of Toxicology 20100701 |
Resistance to cisplatin-induced apoptosis via PI3K-dependent survivin expression in a rat hepatoma cell line. | International journal of oncology 20100701 |
Comfrey (Symphytum Officinale. l.) and Experimental Hepatic Carcinogenesis: A Short-term Carcinogenesis Model Study. | Evidence-based complementary and alternative medicine : eCAM 20100601 |
Suppression of the inflammatory cascade is implicated in resveratrol chemoprevention of experimental hepatocarcinogenesis. | Pharmaceutical research 20100601 |
Evaluation of the heme oxygenase-1 expression in esophagitis and esophageal cancer induced by different reflux experimental models and diethylnitrosamine. | Acta cirurgica brasileira 20100601 |
Resveratrol suppresses oxidative stress and inflammatory response in diethylnitrosamine-initiated rat hepatocarcinogenesis. | Cancer prevention research (Philadelphia, Pa.) 20100601 |
Epigenetic silencing of cell cycle regulatory genes during 3-methylcholanthrene and diethylnitrosamine-induced multistep rat lung cancer. | Molecular carcinogenesis 20100601 |
Inhibitory role of peroxisome proliferator-activated receptor gamma in hepatocarcinogenesis in mice and in vitro. | Hepatology (Baltimore, Md.) 20100601 |
Guidelines for the welfare and use of animals in cancer research. | British journal of cancer 20100525 |
Androgen receptor promotes hepatitis B virus-induced hepatocarcinogenesis through modulation of hepatitis B virus RNA transcription. | Science translational medicine 20100519 |
Tumor promotion by copper-overloading and its enhancement by excess iron accumulation involving oxidative stress responses in the early stage of a rat two-stage hepatocarcinogenesis model. | Chemico-biological interactions 20100514 |
Beneficial effect of metronomic chemotherapy on tumor suppression and survival in a rat model of hepatocellular carcinoma with liver cirrhosis. | Cancer chemotherapy and pharmacology 20100501 |
Chemopreventive effect of bacoside A on N-nitrosodiethylamine-induced hepatocarcinogenesis in rats. | Journal of cancer research and clinical oncology 20100501 |
What role for biologically based dose-response models in estimating low-dose risk? | Environmental health perspectives 20100501 |
Accelerated liver regeneration and hepatocarcinogenesis in mice overexpressing serine-45 mutant beta-catenin. | Hepatology (Baltimore, Md.) 20100501 |
Quantitative multiparametric PROPELLER MRI of diethylnitrosamine-induced hepatocarcinogenesis in wister rat model. | Journal of magnetic resonance imaging : JMRI 20100501 |
Preventive effect of JTE-522, a selective cyclooxygenase-2 inhibitor, on DEN-induced hepatocarcinogenesis in rats. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100501 |
Hepatic oval cells activated by hepatocyte apoptosis in diethylnitrosamine-induced rat liver cirrhosis. | Saudi medical journal 20100501 |
Evaluation of a liver micronucleus assay in young rats (IV): a study using a double-dosing/single-sampling method by the Collaborative Study Group for the Micronucleus Test (CSGMT)/Japanese Environmental Mutagen Society (JEMS)-Mammalian Mutagenicity Study Group (MMS). | Mutation research 20100430 |
Dietary lycopene and tomato extract supplementations inhibit nonalcoholic steatohepatitis-promoted hepatocarcinogenesis in rats. | International journal of cancer 20100415 |
Accelerated hepatocellular carcinoma development in mice expressing the Pim-3 transgene selectively in the liver. | Oncogene 20100415 |
Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer. | Nature communications 20100412 |
Induction of GST-P-positive proliferative lesions facilitating lipid peroxidation with possible involvement of transferrin receptor up-regulation and ceruloplasmin down-regulation from the early stage of liver tumor promotion in rats. | Archives of toxicology 20100401 |
Analysis of nitrosamines migration from condoms in the chinese market using a proper migration experiment. | Bulletin of environmental contamination and toxicology 20100401 |
An approach to the study of gene expression in hepatocarcinogenesis initiation. | Translational oncology 20100401 |
Supplementation of selenium reduces chemical hepatocarcinogenesis in male Sprague-Dawley rats. | Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20100401 |
Nuclear factor-kappa B as a promising target for selenium chemoprevention in rat hepatocarcinogenesis. | Journal of gastroenterology and hepatology 20100401 |
[Immunohistochemical expression of P53 and Ki-67 in diethylnitrosamine-induced carcinomas esophageal: experimental model]. | Revista do Colegio Brasileiro de Cirurgioes 20100401 |
Oxidation of N-Nitrosoalkylamines by human cytochrome P450 2A6: sequential oxidation to aldehydes and carboxylic acids and analysis of reaction steps. | The Journal of biological chemistry 20100312 |
Pfaffia paniculata (Brazilian ginseng) roots decrease proliferation and increase apoptosis but do not affect cell communication in murine hepatocarcinogenesis. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20100301 |
Induction of p53 renders ATM-deficient mice refractory to hepatocarcinogenesis. | Gastroenterology 20100301 |
Integration of in vivo genotoxicity and short-term carcinogenicity assays using F344 gpt delta transgenic rats: in vivo mutagenicity of 2,4-diaminotoluene and 2,6-diaminotoluene structural isomers. | Toxicological sciences : an official journal of the Society of Toxicology 20100301 |
Cytokeratin 8/18 is a useful immunohistochemical marker for hepatocellular proliferative lesions in mice. | The Journal of veterinary medical science 20100301 |
Bacoside A downregulates matrix metalloproteinases 2 and 9 in DEN-induced hepatocellular carcinoma. | Cell biochemistry and function 20100301 |
Screening of N-nitrosamines in tap and swimming pool waters using fast gas chromatography. | Journal of separation science 20100301 |
No Mutations of Lysophosphatidic Acid Receptor Genes in Lung Adenocarcinomas Induced by N-Nitrosobis(2-hydroxypropyl)amine in Rats. | Journal of toxicologic pathology 20100301 |
Antioxidant enzymatically modified isoquercitrin suppresses the development of liver preneoplastic lesions in rats induced by beta-naphthoflavone. | Toxicology 20100209 |
The role of two putative nitroreductases, Frm2p and Hbn1p, in the oxidative stress response in Saccharomyces cerevisiae. | Yeast (Chichester, England) 20100201 |
Dietary supplementation with branched-chain amino acids suppresses diethylnitrosamine-induced liver tumorigenesis in obese and diabetic C57BL/KsJ-db/db mice. | Cancer science 20100201 |
Transcription coactivator PBP/MED1-deficient hepatocytes are not susceptible to diethylnitrosamine-induced hepatocarcinogenesis in the mouse. | Carcinogenesis 20100201 |
Antioxidant enzymatically modified isoquercitrin or melatonin supplementation reduces oxidative stress-mediated hepatocellular tumor promotion of oxfendazole in rats. | Archives of toxicology 20100201 |
Evaluation of the protective effect of ascorbic acid on nitrite- and nitrosamine-induced cytotoxicity and genotoxicity in human hepatoma line. | Toxicology mechanisms and methods 20100201 |
Elevation of cell proliferation via generation of reactive oxygen species by piperonyl butoxide contributes to its liver tumor-promoting effects in mice. | Archives of toxicology 20100201 |
The threshold dose for liver tumor promoting effects of dicyclanil in ICR mice. | The Journal of toxicological sciences 20100201 |
Morin fosters apoptosis in experimental hepatocellular carcinogenesis model. | Chemico-biological interactions 20100127 |
Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression. | Cell 20100122 |
BRE over-expression promotes growth of hepatocellular carcinoma. | Biochemical and biophysical research communications 20100115 |
Unique impact of RB loss on hepatic proliferation: tumorigenic stresses uncover distinct pathways of cell cycle control. | The Journal of biological chemistry 20100108 |
Efficacy of lanreotide in preventing the occurrence of chemically induced hepatocellular carcinoma in rats. | Chemico-biological interactions 20100105 |
Anti-angiogenic therapy on hepatocellular carcinoma development and progression. | The Journal of surgical research 20100101 |
Effect of antisense oligomer in controlling c-raf.1 overexpression during diethylnitrosamine-induced hepatocarcinogenesis in rat. | Cancer chemotherapy and pharmacology 20100101 |
Antioxidant and antimutagenic effect of quercetin against DEN induced hepatotoxicity in rat. | Phytotherapy research : PTR 20100101 |
Insulin-independent promotion of chemically induced hepatocellular tumor development in genetically diabetic mice. | Cancer science 20100101 |
Cytokeratin 8/18 as a new marker of mouse liver preneoplastic lesions. | Toxicology and applied pharmacology 20100101 |
Rat medium-term multi-organ carcinogenesis bioassay of Agaricus blazei Murrill fruit-body extract. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101 |
The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis. | Cancer research 20100101 |
Carbogen gas-challenge BOLD MR imaging in a rat model of diethylnitrosamine-induced liver fibrosis. | Radiology 20100101 |
Inhibition of poly adenosine diphosphate-ribose polymerase decreases hepatocellular carcinoma growth by modulation of tumor-related gene expression. | Hepatology (Baltimore, Md.) 20100101 |
Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo. | PLoS genetics 20100101 |
The liver-selective thyromimetic T-0681 influences reverse cholesterol transport and atherosclerosis development in mice. | PloS one 20100101 |
Inhibition by licorice flavonoid oil of glutathione S-transferase-positive foci in the medium-term rat hepatocarcinogenesis bioassay. | Nutrition research (New York, N.Y.) 20100101 |
Effect of selenium-enriched malt on VEGF and several relevant angiogenic cytokines in diethylnitrosamine-induced hepatocarcinoma rats. | Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20100101 |
Comparison of lung cancer cell lines representing four histopathological subtypes with gene expression profiling using quantitative real-time PCR. | Cancer cell international 20100101 |
Maternal characteristics associated with the dietary intake of nitrates, nitrites, and nitrosamines in women of child-bearing age: a cross-sectional study. | Environmental health : a global access science source 20100101 |
The AP-1 repressor protein, JDP2, potentiates hepatocellular carcinoma in mice. | Molecular cancer 20100101 |
Early limited nitrosamine exposures exacerbate high fat diet-mediated type 2 diabetes and neurodegeneration. | BMC endocrine disorders 20100101 |
Cytosolic Hsp60 is involved in the NF-kappaB-dependent survival of cancer cells via IKK regulation. | PloS one 20100101 |
Nuclear translocation of telomerase reverse transcriptase: a critical process in chemical induced hepatocellular carcinogenesis. | Neoplasma 20100101 |
Nuclear receptor CAR represses TNFalpha-induced cell death by interacting with the anti-apoptotic GADD45B. | PloS one 20100101 |
Cyanobacterial cyclopeptides as lead compounds to novel targeted cancer drugs. | Marine drugs 20100101 |
PPARalpha: energy combustion, hypolipidemia, inflammation and cancer. | Nuclear receptor signaling 20100101 |
Cruciferous vegetable intake is inversely associated with lung cancer risk among smokers: a case-control study. | BMC cancer 20100101 |
Application of magnetic resonance imaging in transgenic and chemical mouse models of hepatocellular carcinoma. | Molecular cancer 20100101 |
Differential chemosensitization of P-glycoprotein overexpressing K562/Adr cells by withaferin A and Siamois polyphenols. | Molecular cancer 20100101 |
Effect of allyl isothiocyanate (AITC) in both nitrite- and nitrosamine-induced cell death, production of reactive oxygen species, and DNA damage by the single-cell gel electrophoresis (SCGE): does it have any protective effect on HepG2 cells? | International journal of toxicology 20100101 |
Chemopreventive potential of beta-Sitosterol in experimental colon cancer model--an in vitro and In vivo study. | BMC complementary and alternative medicine 20100101 |
Integrative and comparative genomics analysis of early hepatocellular carcinoma differentiated from liver regeneration in young and old. | Molecular cancer 20100101 |
[O-aminoazotoluene inhibits DENA-induced hepatocarcinogenesis when used together in mice]. | Voprosy onkologii 20100101 |
Stress as a possible mechanism in melanoma progression. | Dermatology research and practice 20100101 |
Carcinogenic risk assessment: are there dose thresholds for carcinogens? | Asian Pacific journal of cancer prevention : APJCP 20100101 |
Mouse model of carbon tetrachloride induced liver fibrosis: Histopathological changes and expression of CD133 and epidermal growth factor. | BMC gastroenterology 20100101 |
Lack of guanylate cyclase C results in increased mortality in mice following liver injury. | BMC gastroenterology 20100101 |
Anticancer activity of a sub-fraction of dichloromethane extract of Strobilanthes crispus on human breast and prostate cancer cells in vitro. | BMC complementary and alternative medicine 20100101 |
Serum N-glycome biomarker for monitoring development of DENA-induced hepatocellular carcinoma in rat. | Molecular cancer 20100101 |
Role of nicotinamide in DNA damage, mutagenesis, and DNA repair. | Journal of nucleic acids 20100101 |
Kinetics of angiogenic changes in a new mouse model for hepatocellular carcinoma. | Molecular cancer 20100101 |
Coactivators in PPAR-Regulated Gene Expression. | PPAR research 20100101 |
Phyllanthus spp. induces selective growth inhibition of PC-3 and MeWo human cancer cells through modulation of cell cycle and induction of apoptosis. | PloS one 20100101 |
SOCS1, a Negative Regulator of Cytokine Signals and TLR Responses, in Human Liver Diseases. | Gastroenterology research and practice 20100101 |
Ginger ingredients inhibit the development of diethylnitrosoamine induced premalignant phenotype in rat chemical hepatocarcinogenesis model. | BioFactors (Oxford, England) 20100101 |
Genetic composition of laboratory stocks of the self-fertilizing fish Kryptolebias marmoratus: a valuable resource for experimental research. | PloS one 20100101 |
TLRs, NF-κB, JNK, and Liver Regeneration. | Gastroenterology research and practice 20100101 |
Protective effects and potential mechanisms of Pien Tze Huang on cerebral chronic ischemia and hypertensive stroke. | Chinese medicine 20100101 |
Thymoquinone attenuates diethylnitrosamine induction of hepatic carcinogenesis through antioxidant signaling. | Oxidative medicine and cellular longevity 20100101 |
Genomic analysis of microRNA time-course expression in liver of mice treated with genotoxic carcinogen N-ethyl-N-nitrosourea. | BMC genomics 20100101 |
How many antiviral small interfering RNAs may be encoded by the mammalian genomes? | Biology direct 20100101 |
Fresh raspberry phytochemical extract inhibits hepatic lesion in a Wistar rat model. | Nutrition & metabolism 20100101 |
Chemopreventive and hepatoprotective effects of embelin on N-nitrosodiethylamine and carbon tetrachloride induced preneoplasia and toxicity in rat liver. | Asian Pacific journal of cancer prevention : APJCP 20100101 |
NF-κB, JNK, and TLR Signaling Pathways in Hepatocarcinogenesis. | Gastroenterology research and practice 20100101 |
Protective effect of Cassia fistula Linn. on diethylnitrosamine induced hepatocellular damage and oxidative stress in ethanol pretreated rats. | Biological research 20100101 |
Oxidative stress induced by lead and antioxidant potential of certain adaptogens in poultry. | Toxicology international 20100101 |
MicroRNAs involved in neoplastic transformation of liver cancer stem cells. | Journal of experimental & clinical cancer research : CR 20100101 |
Oral methylthioadenosine administration attenuates fibrosis and chronic liver disease progression in Mdr2-/- mice. | PloS one 20100101 |
Doxorubicin toxicity can be ameliorated during antioxidant L-carnitine supplementation. | Oxidative medicine and cellular longevity 20100101 |
TLRs, Alcohol, HCV, and Tumorigenesis. | Gastroenterology research and practice 20100101 |
Anti-mutagenic and anti-carcinogenic potential of the carotenoid meso-zeaxanthin. | Asian Pacific journal of cancer prevention : APJCP 20100101 |
A comparison of the cytotoxic potential of standardized aqueous and ethanolic extracts of a polyherbal mixture comprised of Nigella sativa (seeds), Hemidesmus indicus (roots) and Smilax glabra (rhizome). | Pharmacognosy research 20100101 |
Solanum trilobatum in the management of atopy: Through inhibition of mast cell degranulation and moderation of release of interleukins. | Pharmacognosy research 20100101 |
Curcumin-the paradigm of a multi-target natural compound with applications in cancer prevention and treatment. | Toxins 20100101 |
Changes of splenic macrophage during the process of liver cancer induced by diethylnitrosamine in rats. | Chinese medical journal 20091220 |
Diethylnitrosamine (DEN) induces irreversible hepatocellular carcinogenesis through overexpression of G1/S-phase regulatory proteins in rat. | Toxicology letters 20091215 |
Inhibitory effect of tea polyphenols on hepatic preneoplastic foci in Wistar rats. | Investigational new drugs 20091201 |
Effect of selenium-enriched malt on hypoglycemia and regulatory hormones in diethylnitrosamine-induced hepatocarcinoma SD rats. | Research in veterinary science 20091201 |
A computer-aided diagnostic system to discriminate SPIO-enhanced magnetic resonance hepatocellular carcinoma by a neural network classifier. | Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society 20091201 |
N-Nitrosopiperidine and N-Nitrosodibutylamine induce apoptosis in HepG2 cells via the caspase dependent pathway. | Cell biology international 20091201 |
Potassium bromate enhances N-ethyl-N-hydroxyethylnitrosamine-induced kidney carcinogenesis only at high doses in Wistar rats: indication of the existence of an enhancement threshold. | Toxicologic pathology 20091201 |
Circadian disruption in experimental cancer processes. | Integrative cancer therapies 20091201 |
Liver cell transformation in chronic HBV infection. | Viruses 20091201 |
Cyclooxygenase 2 and Prostaglandin E2 are not Involved in N-Nitrosodiethylamine-Initiated Early Rat Hepatocarcinogenesis. | Journal of toxicologic pathology 20091201 |
Characteristic upregulation of glucose-regulated protein 78 in an early lesion negative for hitherto established cytochemical markers in rat hepatocarcinogenesis. | Journal of toxicologic pathology 20091201 |
Hepatoprotective activity of bacoside A against N-nitrosodiethylamine-induced liver toxicity in adult rats. | Cell biology and toxicology 20091001 |
A diet rich in cocoa attenuates N-nitrosodiethylamine-induced liver injury in rats. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20091001 |
Mechanistic study on hepatocarcinogenesis of piperonyl butoxide in mice. | Toxicologic pathology 20091001 |
In vitro antioxidant and antihyperlipidemic activities of Bauhinia variegata Linn. | Indian journal of pharmacology 20091001 |
Hepatoprotective and anti-hepatocarcinogenic effects of glycyrrhizin and matrine. | Chemico-biological interactions 20090914 |
Potential chemoprevention of N-nitrosodiethylamine-induced hepatocarcinogenesis by polyphenolics from Acacia nilotica bark. | Chemico-biological interactions 20090914 |
Measuring microenvironment mechanical stress of rat liver during diethylnitrosamine induced hepatocarcinogenesis by atomic force microscope. | Microscopy research and technique 20090901 |
Detection and toxicity assessment of nitrosamines migration from latex gloves in the Chinese market. | International journal of hygiene and environmental health 20090901 |
[Differentially expressed proteins in the precancerous stage of rat hepatocarcinogenesis induced by diethylnitrosamine]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090901 |
Expression of intercellular adhesion molecule-1 in the livers of rats treated with diethylnitrosamine. | Journal of clinical biochemistry and nutrition 20090901 |
[Inhibitory effect of thyroxine on late stages of hepatocarcinogenesis induced in suckling mice by diethylnitrosamine]. | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20090901 |
Dynamic changes in DNA methylation during multistep rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine. | Toxicology letters 20090825 |
Morin regulates the expression of NF-kappaB-p65, COX-2 and matrix metalloproteinases in diethylnitrosamine induced rat hepatocellular carcinoma. | Chemico-biological interactions 20090814 |
The mysterious steps in carcinogenesis. | British journal of cancer 20090804 |
DNA-repair genes and vitamin E in the prevention of N-nitrosodiethylamine mutagenicity. | Cell biology and toxicology 20090801 |
Chemopreventive potential of Epoxy clerodane diterpene from Tinospora cordifolia against diethylnitrosamine-induced hepatocellular carcinoma. | Investigational new drugs 20090801 |
The constitutive active/androstane receptor facilitates unique phenobarbital-induced expression changes of genes involved in key pathways in precancerous liver and liver tumors. | Toxicological sciences : an official journal of the Society of Toxicology 20090801 |
Antioxidant Effect of CoQ(10) on N-nitrosodiethylamine-induced Oxidative Stress in Mice. | The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20090801 |
Protective role of chickpea seed coat fibre on N-nitrosodiethylamine-induced toxicity in hypercholesterolemic rats. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20090701 |
Maté attenuates DNA damage and carcinogenesis induced by diethylnitrosamine and thermal injury in rat esophagus. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090701 |
Cytokeratin 8/18 overexpression and complex formation as an indicator of GST-P positive foci transformation into hepatocellular carcinomas. | Toxicology and applied pharmacology 20090701 |
The Ras inhibitor farnesylthiosalicyclic acid (FTS) prevents nodule formation and development of preneoplastic foci of altered hepatocytes in rats. | European journal of cancer (Oxford, England : 1990) 20090701 |
Effect of Chokeberry (Aronia melanocarpa) juice on the metabolic activation and detoxication of carcinogenic N-nitrosodiethylamine in rat liver. | Journal of agricultural and food chemistry 20090610 |
Viral hepatitis-associated intrahepatic cholangiocarcinoma shares common disease processes with hepatocellular carcinoma. | British journal of cancer 20090602 |
Silymarin attenuated mast cell recruitment thereby decreased the expressions of matrix metalloproteinases-2 and 9 in rat liver carcinogenesis. | Investigational new drugs 20090601 |
Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis. | Molecular carcinogenesis 20090601 |
Inhibition of c-Jun NH2-terminal kinase switches Smad3 signaling from oncogenesis to tumor- suppression in rat hepatocellular carcinoma. | Hepatology (Baltimore, Md.) 20090601 |
Celecoxib enhances the detoxification of diethylnitrosamine in rat liver cancer. | World journal of gastroenterology 20090521 |
Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: inhibition of cell proliferation and induction of apoptosis. | Chemico-biological interactions 20090515 |
Involvement of oxidative stress in hepatocellular tumor-promoting activity of oxfendazole in rats. | Archives of toxicology 20090501 |
Echographic detection of diethylnitrosamine-induced liver tumors in rats and the effect of the intratumoral injection of an inhibitor of c-Jun N-terminal kinase. | Journal of gastroenterology and hepatology 20090501 |
Predominant modifier of extreme liver cancer susceptibility in C57BR/cdJ female mice localized to 6 Mb on chromosome 17. | Carcinogenesis 20090501 |
Hepatocarcinogenesis in mice with a conditional knockout of the hepatocyte growth factor receptor c-Met. | International journal of cancer 20090415 |
Thyroid hormone receptor ligands induce regression of rat preneoplastic liver lesions causing their reversion to a differentiated phenotype. | Hepatology (Baltimore, Md.) 20090401 |
Molecular signatures of N-nitroso compounds in Caco-2 cells: implications for colon carcinogenesis. | Toxicological sciences : an official journal of the Society of Toxicology 20090401 |
Role of vitamin-E on rat liver-amiodarone: an ultrastructural study. | Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20090401 |
[Inhibitory effects of Scutellaria barbate extracts on diethylnitrosamine-induced hepatocarcinoma in rats]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090401 |
[An improved BALB/c 3T3 cell transformation assay and its application in the cocarcinogenesis study]. | Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 20090401 |
Protective effect of red beetroot against carbon tetrachloride- and N-nitrosodiethylamine-induced oxidative stress in rats. | Journal of agricultural and food chemistry 20090325 |
Progression of diethylnitrosamine-induced hepatic carcinogenesis in carnitine-depleted rats. | World journal of gastroenterology 20090321 |
Targeted deletion of hepatocyte Ikkbeta confers growth advantages. | Biochemical and biophysical research communications 20090306 |
Tumor promoting and co-carcinogenic effects in medium-term rat hepatocarcinogenesis are not modified by co-administration of 12 pesticides in mixture at acceptable daily intake. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090301 |
Chemical genomics of cancer chemopreventive dithiolethiones. | Carcinogenesis 20090301 |
[Prevention of hepatic tumor growth and metastasis in rats with rapamycin]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090301 |
Irradiated Chinese Rugao ham: Changes in volatile N-nitrosamine, biogenic amine and residual nitrite during ripening and post-ripening. | Meat science 20090301 |
Biological Basis of Differential Susceptibility to Hepatocarcinogenesis among Mouse Strains. | Journal of toxicologic pathology 20090301 |
Dose-dependent alterations in gene expression in mouse liver induced by diethylnitrosamine and ethylnitrosourea and determined by quantitative real-time PCR. | Mutation research 20090219 |
Regulation of iron metabolism-related genes in diethylnitrosamine-induced mouse liver tumors. | Toxicology letters 20090210 |
Hepatocarcinogenic susceptibility of rasH2 mice to troglitazone in a two-stage hepatocarcinogenesis model. | Archives of toxicology 20090201 |
Threshold dose of piperonyl butoxide that induces reactive oxygen species-mediated hepatocarcinogenesis in rats. | Archives of toxicology 20090201 |
Nonalcoholic steatohepatitis induced by a high-fat diet promotes diethylnitrosamine-initiated early hepatocarcinogenesis in rats. | International journal of cancer 20090201 |
Metalloproteinases 2 and 9 activity during promotion and progression stages of rat liver carcinogenesis. | Journal of molecular histology 20090201 |
Hepatocyte-specific activation of NF-kappaB does not aggravate chemical hepatocarcinogenesis in transgenic mice. | The Journal of pathology 20090201 |
Inhibition of reactive oxygen species and pre-neoplastic lesions by quercetin through an antioxidant defense mechanism. | Free radical research 20090201 |
Suppressive effect of Siraitia grosvenorii extract on dicyclanil-promoted hepatocellular proliferative lesions in male mice. | The Journal of toxicological sciences 20090201 |
Detection and characterization of hepatocellular carcinoma in rats with liver cirrhosis: diagnostic value of combined use of MR positive and negative contrast agents. | Hepatobiliary & pancreatic diseases international : HBPD INT 20090201 |
[The expression of B-cell translocation gene 2 in diethylnitrosamine-induced primary hepatocellular carcinoma rat model.]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090201 |
High mobility group box associated with cell proliferation appears to play an important role in hepatocellular carcinogenesis in rats and humans. | Toxicology 20090131 |
Frequent mutations of lysophosphatidic acid receptor-1 gene in rat liver tumors. | Mutation research 20090115 |
Time course evaluation of N-nitrosodialkylamines-induced DNA alkylation and oxidation in liver of mosquito fish. | Mutation research 20090115 |
Molecular therapy for the treatment of hepatocellular carcinoma. | British journal of cancer 20090113 |
Evaluation of a liver micronucleus assay with 12 chemicals using young rats (II): a study by the Collaborative Study Group for the Micronucleus Test/Japanese Environmental Mutagen Society-Mammalian Mutagenicity Study Group. | Mutagenesis 20090101 |
Enhancement of preneoplastic lesion yield by Chios Mastic Gum in a rat liver medium-term carcinogenesis bioassay. | Toxicology and applied pharmacology 20090101 |
Chemoprotective properties of rooibos (Aspalathus linearis), honeybush (Cyclopia intermedia) herbal and green and black (Camellia sinensis) teas against cancer promotion induced by fumonisin B1 in rat liver. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090101 |
Protective action of indole-3-acetic acid on induced hepatocarcinoma in mice. | Cell biochemistry and function 20090101 |
Identification of N-nitrosamines in treated drinking water using nanoelectrospray ionization high-field asymmetric waveform ion mobility spectrometry with quadrupole time-of-flight mass spectrometry. | Journal of chromatographic science 20090101 |
Keratinocytes as depository of ammonium-inducible glutamine synthetase: age- and anatomy-dependent distribution in human and rat skin. | PloS one 20090101 |
Evaluation of centrosome abnormalities and p53 inactivation in chemical induced hepatocellular carcinogenesis. | Neoplasma 20090101 |
In vivo evidence of hepato- and reno-protective effect of garlic oil against sodium nitrite-induced oxidative stress. | International journal of biological sciences 20090101 |
Expression and correlation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor and microvessel density in experimental rat hepatocarcinogenesis. | The Journal of international medical research 20090101 |
Role of the vitamin C in diethylnitrosamine-induced esophageal cancer in Wistar rats. | Acta cirurgica brasileira 20090101 |
Preventive effect of the flavonoid, quercetin, on hepatic cancer in rats via oxidant/antioxidant activity: molecular and histological evidences. | Journal of experimental & clinical cancer research : CR 20090101 |
Chemoprevention of rat liver toxicity and carcinogenesis by Spirulina. | International journal of biological sciences 20090101 |
Studies on mode of action of hexaammine Co(III) chloride against diethylnitrosamine-induced hepatocarcinogenesis in mice. | Journal of biochemical and molecular toxicology 20090101 |
Mechanisms of nitrosamine-mediated neurodegeneration: potential relevance to sporadic Alzheimer's disease. | Journal of Alzheimer's disease : JAD 20090101 |
In vitro growth environment produces lipidomic and electron transport chain abnormalities in mitochondria from non-tumorigenic astrocytes and brain tumours. | ASN neuro 20090101 |
Characteristic gene expression profiles in the progression from liver cirrhosis to carcinoma induced by diethylnitrosamine in a rat model. | Journal of experimental & clinical cancer research : CR 20090101 |
Assessment of the effect of betaine on p16 and c-myc DNA methylation and mRNA expression in a chemical induced rat liver cancer model. | BMC cancer 20090101 |
Deleted in liver cancer 2 (DLC2) was dispensable for development and its deficiency did not aggravate hepatocarcinogenesis. | PloS one 20090101 |
Protective effects of garlic and silymarin on NDEA-induced rats hepatotoxicity. | International journal of biological sciences 20090101 |
Circadian disruption accelerates liver carcinogenesis in mice. | Mutation research 20090101 |
Antiviral activity of gliotoxin, gentian violet and brilliant green against Nipah and Hendra virus in vitro. | Virology journal 20090101 |
A combination of indol-3-carbinol and genistein synergistically induces apoptosis in human colon cancer HT-29 cells by inhibiting Akt phosphorylation and progression of autophagy. | Molecular cancer 20090101 |
Mutagenicity of Chinese traditional medicine Semen Armeniacae amarum by two modified Ames tests. | BMC complementary and alternative medicine 20090101 |
Chitosan-alginate sponge: preparation and application in curcumin delivery for dermal wound healing in rat. | Journal of biomedicine & biotechnology 20090101 |
Spontaneous regression of advanced hepatocellular carcinoma: a case report. | Cases journal 20090101 |
[Diethylnitrosamine-induced carcinogenesis in PARP-1(-/-) and PARP-1(+/+) mice]. | Voprosy onkologii 20090101 |
Nitrosamine exposure exacerbates high fat diet-mediated type 2 diabetes mellitus, non-alcoholic steatohepatitis, and neurodegeneration with cognitive impairment. | Molecular neurodegeneration 20090101 |
The role of scavenger receptor B1 in infection with Mycobacterium tuberculosis in a murine model. | PloS one 20090101 |
Modulatory effects of alpha- and gamma-tocopherols on 4-hydroxyestradiol induced oxidative stresses in MCF-10A breast epithelial cells. | Nutrition research and practice 20090101 |
Ursolic acid attenuates oxidative stress-mediated hepatocellular carcinoma induction by diethylnitrosamine in male Wistar rats. | Asian Pacific journal of cancer prevention : APJCP 20090101 |
Sida rhombifolia ssp. retusa seed extract inhibits DEN induced murine hepatic preneoplasia and carbon tetrachloride hepatotoxicity. | Asian Pacific journal of cancer prevention : APJCP 20090101 |
Nitrosamine exposure causes insulin resistance diseases: relevance to type 2 diabetes mellitus, non-alcoholic steatohepatitis, and Alzheimer's disease. | Journal of Alzheimer's disease : JAD 20090101 |
Hamster exhibits major differences in organ-specific metabolism of the esophageal carcinogen N-nitrosodiethylamine. | Toxicology letters 20081215 |
Urethane and N-nitrosodiethylamine are mutagenic for the Syrian hamster fetus. | Mutation research 20081208 |
Antiproliferative potential of gallic acid against diethylnitrosamine-induced rat hepatocellular carcinoma. | Molecular and cellular biochemistry 20081201 |
Role of Nrf2 and oxidative stress on fenofibrate-induced hepatocarcinogenesis in rats. | Toxicological sciences : an official journal of the Society of Toxicology 20081201 |
Protective effect of Juzen-taiho-to on hepatocarcinogenesis is mediated through the inhibition of Kupffer cell-induced oxidative stress. | International journal of cancer 20081201 |
Hepatocarcinogenic susceptibility of fenofibrate and its possible mechanism of carcinogenicity in a two-stage hepatocarcinogenesis model of rasH2 mice. | Toxicologic pathology 20081201 |
Altered {beta}-catenin accumulation in hepatocellular carcinomas of diethylnitrosamine-exposed rhesus macaques. | Toxicologic pathology 20081201 |
Impact of insulin resistance on the progression of chronic liver diseases. | International journal of molecular medicine 20081201 |
Effect of berberine on hepatocyte proliferation, inducible nitric oxide synthase expression, cytochrome P450 2E1 and 1A2 activities in diethylnitrosamine- and phenobarbital-treated rats. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20081101 |
Molecular modeling of nitrosamines adsorbed on H-ZSM-5 zeolite: an ONIOM study. | Journal of molecular modeling 20081101 |
Pre-bled-young-rats in genotoxicity testing: a model for peripheral blood micronucleus assay. | Regulatory toxicology and pharmacology : RTP 20081101 |
Effect of antioxidant phytochemicals on the hepatic tumor promoting activity of 3,3',4,4'-tetrachlorobiphenyl (PCB-77). | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081101 |
Diallyl sulfide protects against N-nitrosodiethylamine-induced liver tumorigenesis: role of aldose reductase. | World journal of gastroenterology 20081028 |
Inhibition of the promotion of hepatocarcinogenesis by 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153) by the deletion of the p50 subunit of NF-kappa B in mice. | Toxicology and applied pharmacology 20081015 |
Dual therapeutic effects of interferon-alpha gene therapy in a rat hepatocellular carcinoma model with liver cirrhosis. | Molecular therapy : the journal of the American Society of Gene Therapy 20081001 |
[Changes in TGF-beta1/Smads signaling pathway in rats with chemical hepatocarcinogenesis]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20081001 |
Possible involvement of oxidative stress in fenofibrate-induced hepatocarcinogenesis in rats. | Archives of toxicology 20080901 |
The effect of the aqueous extract of the roots of Asparagus racemosus on hepatocarcinogenesis initiated by diethylnitrosamine. | Phytotherapy research : PTR 20080901 |
Antioxidant effects of flavonoids used as food additives (purple corn color, enzymatically modified isoquercitrin, and isoquercitrin) on liver carcinogenesis in a rat medium-term bioassay. | Journal of food science 20080901 |
The protective effects of demethoxyviridine and 1-alpha-hydroxy-demethoxyviridine in the livers of male rats treated with diethylnitrosamine and 2-acetylaminflourene. | Saudi medical journal 20080901 |
Therapeutic actions of melatonin in cancer: possible mechanisms. | Integrative cancer therapies 20080901 |
Mutagenicity of N-nitrosodiethanolamine in a V79-derived cell line expressing two human biotransformation enzymes. | Mutation research 20080825 |
Analysis of nitrosamines in water by automated SPE and isotope dilution GC/HRMS Occurrence in the different steps of a drinking water treatment plant, and in chlorinated samples from a reservoir and a sewage treatment plant effluent. | Talanta 20080815 |
Hepatocyte necrosis induced by oxidative stress and IL-1 alpha release mediate carcinogen-induced compensatory proliferation and liver tumorigenesis. | Cancer cell 20080812 |
Carcinogenic risk of copper gluconate evaluated by a rat medium-term liver carcinogenicity bioassay protocol. | Archives of toxicology 20080801 |
Elevated activity of the oxidative and non-oxidative pentose phosphate pathway in (pre)neoplastic lesions in rat liver. | International journal of experimental pathology 20080801 |
Mouse model of diethylnitrosamine-induced gastric cancer. | The Journal of surgical research 20080801 |
Modifying effects of chitin, chitosan and their related compounds on 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in a rat medium-term hepatocarcinogenesis model, and their post-initiation effects in a female rat 2-stage multi-organ carcinogenesis model. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080801 |
Effect of carotenoids on in vitro proliferation and differentiation of oval cells during neoplastic and non-neoplastic liver injuries in rats. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080801 |
The use of isolated human lymphocytes in mycotoxin cytotoxicity testing. | International journal of molecular sciences 20080801 |
Effect of in vivo loss of GDF-15 on hepatocellular carcinogenesis. | Journal of cancer research and clinical oncology 20080701 |
Evidence that the anticarcinogenic effect of caffeic acid phenethyl ester in the resistant hepatocyte model involves modifications of cytochrome P450. | Toxicological sciences : an official journal of the Society of Toxicology 20080701 |
Formation of N-nitrosamines from eleven disinfection treatments of seven different surface waters. | Environmental science & technology 20080701 |
Effect of DENA induced hepatocarcinogenesis on neuroendocrine levels in male rats. | Indian journal of experimental biology 20080701 |
Emblica officinalis and hepatocarcinogenesis: a chemopreventive study in Wistar rats. | Journal of ethnopharmacology 20080619 |
Two-dimensional differential gel electrophoresis/analysis of diethylnitrosamine induced rat hepatocellular carcinoma. | International journal of cancer 20080615 |
Tumor promotion in liver of mice with a conditional Cx26 knockout. | Toxicological sciences : an official journal of the Society of Toxicology 20080601 |
Silymarin downregulates COX-2 expression and attenuates hyperlipidemia during NDEA-induced rat hepatocellular carcinoma. | Molecular and cellular biochemistry 20080601 |
Tomato oleoresin inhibits DNA damage but not diethylnitrosamine-induced rat hepatocarcinogenesis. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20080601 |
Defective DNA strand break repair causes chromosomal instability and accelerates liver carcinogenesis in mice. | Hepatology (Baltimore, Md.) 20080601 |
Intra-portal transplantation of bone marrow stromal cells ameliorates liver fibrosis in mice. | Hepatobiliary & pancreatic diseases international : HBPD INT 20080601 |
Chemical carcinogenesis studies in nonhuman primates. | Proceedings of the Japan Academy. Series B, Physical and biological sciences 20080601 |
Transplanted bone marrow stromal cells are not cellular origin of hepatocellular carcinomas in a mouse model of carcinogenesis. | World journal of gastroenterology 20080521 |
Protective effects of Ginkgo biloba against rat liver carcinogenesis. | Chemico-biological interactions 20080509 |
Possible carcinogenic risks of copper gluconate and their prevention by co-administered green tea catechins evaluated by a rat medium-term multi-organ carcinogenicity bioassay protocol. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080501 |
TIS21 negatively regulates hepatocarcinogenesis by disruption of cyclin B1-Forkhead box M1 regulation loop. | Hepatology (Baltimore, Md.) 20080501 |
Concurrent administration of ascorbic acid enhances liver tumor-promoting activity of kojic acid in rats. | The Journal of toxicological sciences 20080501 |
Potential inhibitory effects of D-allose, a rare sugar, on liver preneoplastic lesion development in F344 rat medium-term bioassay. | Journal of bioscience and bioengineering 20080501 |
Repression of Ah receptor and induction of transforming growth factor-beta genes in DEN-induced mouse liver tumors. | Toxicology 20080418 |
Thrombospondin-1 expression correlates with angiogenesis in experimental cirrhosis. | World journal of gastroenterology 20080414 |
Binding of MutS protein to oligonucleotides containing a methylated or an ethylated guanine residue, and correlation with mutation frequency. | Mutation research 20080402 |
Efficacy of doxorubicin coupled to lactosaminated albumin on rat hepatocellular carcinomas evaluated by ultrasound imaging. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20080401 |
N-nitrosodiethylamine-induced toxicity in relation to oxidative stress and development of atherosclerosis in hypercholesterolemic diet-fed rabbits. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20080401 |
Promotion potential of madder color in a medium-term multi-organ carcinogenesis bioassay model in F344 rats. | Journal of food science 20080401 |
The differential NF-kB modulation by S-adenosyl-L-methionine, N-acetylcysteine and quercetin on the promotion stage of chemical hepatocarcinogenesis. | Free radical research 20080401 |
[Dendritic cell vaccine modified by murine mAFP gene enhances immunoprotective effect on liver carcinogenesis and tumor development in mice]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20080401 |
Monitoring of N-nitrosodiethanolamine in cosmetic products by ion-pair complex liquid chromatography and identification with negative ion electrospray ionization mass spectrometry. | Journal of chromatography. A 20080321 |
Decreased hepatic 5-HT1A receptors during liver regeneration and neoplasia in rats. | Neurochemical research 20080301 |
Antigenotoxicity and antimutagenicity of lycopene in HepG2 cell line evaluated by the comet assay and micronucleus test. | Toxicology in vitro : an international journal published in association with BIBRA 20080301 |
Sodium selenite enhances glutathione peroxidase activity and DNA strand breaks in hepatoma induced by N-nitrosodiethylamine and promoted by phenobarbital. | Molecular and cellular biochemistry 20080301 |
Prevention of N-nitrosodiethylamine-induced hepatocarcinogenesis by S-allylcysteine. | Molecular and cellular biochemistry 20080301 |
Anti-tumor effect of pegylated interferon in the rat hepatocarcinogenesis model. | International journal of oncology 20080301 |
Effect of dietary selenium on the promotion of hepatocarcinogenesis by 3,3', 4,4'-tetrachlorobiphenyl and 2,2', 4,4', 5,5'-hexachlorobiphenyl. | Experimental biology and medicine (Maywood, N.J.) 20080301 |
Antioxidant potential of thyme extract: alleviation of N-nitrosodiethylamine-induced oxidative stress. | Human & experimental toxicology 20080301 |
beta-Naphthoflavone enhances oxidative stress responses and the induction of preneoplastic lesions in a diethylnitrosamine-initiated hepatocarcinogenesis model in partially hepatectomized rats. | Toxicology 20080227 |
Persistent and remodeling hepatic preneoplastic lesions present differences in cell proliferation and apoptosis, as well as in p53, Bcl-2 and NF-kappaB pathways. | Journal of cellular biochemistry 20080201 |
N-nitrosodimethylamine (NDMA) formation during ozonation of dimethylamine-containing waters. | Water research 20080201 |
Differential selection for B-raf and Ha-ras mutated liver tumors in mice with high and low susceptibility to hepatocarcinogenesis. | Mutation research 20080201 |
Inflammation, HCC and sex: IL-6 in the centre of the triangle. | Journal of hepatology 20080201 |
Systems biological and mechanistic modelling of radiation-induced cancer. | Radiation and environmental biophysics 20080201 |
Anti-tumor effects of cimetidine on hepatocellular carcinomas in diethylnitrosamine-treated rats. | Oncology reports 20080201 |
Chronic ethanol intake promotes double gluthatione S-transferase/transforming growth factor-alpha-positive hepatocellular lesions in male Wistar rats. | Cancer science 20080201 |
Attenuation of N-nitrosodiethylamine-induced hepatocellular carcinogenesis by a novel flavonol-Morin. | Chemico-biological interactions 20080110 |
TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis. | The Journal of clinical investigation 20080102 |
Inactivation of p27Kip1 promotes chemical mouse liver tumorigenesis in the resistant strain C57BL/6J. | Molecular carcinogenesis 20080101 |
N-nitrosodimethylamine (NDMA) removal by reverse osmosis and UV treatment and analysis via LC-MS/MS. | Water research 20080101 |
Alpha-lipoic acid promotes the growth of rat hepatic pre-neoplastic lesions in the choline-deficient model. | Carcinogenesis 20080101 |
Targeting MEK is effective chemoprevention of hepatocellular carcinoma in TGF-alpha-transgenic mice. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20080101 |
24-hour rhythms in oxidative stress during hepatocarcinogenesis in rats: effect of melatonin or alpha-ketoglutarate. | Redox report : communications in free radical research 20080101 |
Adenovirus vector-mediated gene therapy using iodized oil esters for hepatocellular carcinoma in rats. | Anticancer research 20080101 |
Morphine does no promote esophageal carcinogenesis in rats exposed to diethylnitrosamine. | Arquivos de gastroenterologia 20080101 |
The Role of PPARgamma in Hepatocellular Carcinoma. | PPAR research 20080101 |
Reduction by dietary matrix metalloproteinase inhibitor BAY 12-9566N of neoplastic development induced by diethylnitrosamine, N-nitrosodimethylamine, or 7,12-dimethylbenz(a)anthracene in rats. | Drug and chemical toxicology 20080101 |
Effect of black tea in diethylnitrosamine-induced esophageal carcinogenesis in mice. | Acta cirurgica brasileira 20080101 |
Comet assay analysis of single-stranded DNA breaks in circulating leukocytes of glaucoma patients. | Molecular vision 20080101 |
Vesicular flavonoid in combating diethylnitrosamine induced hepatocarcinoma in rat model. | Journal of experimental therapeutics & oncology 20080101 |
Non invasive in vivo investigation of hepatobiliary structure and function in STII medaka (Oryzias latipes): methodology and applications. | Comparative hepatology 20080101 |
Targeting aspartate aminotransferase in breast cancer. | Breast cancer research : BCR 20080101 |
The Role of NF-kappaB in PPARalpha-Mediated Hepatocarcinogenesis. | PPAR research 20080101 |
Diethylnitrosamine-induced hepatic lesions are greater in rats maintained under a light-dark cycle than under constant light, related to the locomotor activity rhythm. | Asian Pacific journal of cancer prevention : APJCP 20080101 |
Modulation of energy metabolic enzyme expression in N-nitrosodiethylamine-mediated hepatocarcinogenesis by Chinese herbs, Huqi San. | BioFactors (Oxford, England) 20080101 |
Pre- and post-initiation modulating effects of green tea ingestion on rat hepatocarcinogenesis. | Nutrition research and practice 20080101 |
Dehydroepiandrosterone supplement increases malate dehydrogenase activity and decreases NADPH-dependent antioxidant enzyme activity in rat hepatocellular carcinogenesis. | Nutrition research and practice 20080101 |
Interaction of N-nitrosodiethylamine/bovine serum albumin complexes with 1,2-dipalmitoyl-sn-glycero-3-phosphocholine monolayers at the air-water interface. | Journal of colloid and interface science 20071215 |
Fat transforms ascorbic acid from inhibiting to promoting acid-catalysed N-nitrosation. | Gut 20071201 |
Inhibition of early preneoplastic events in the rat liver by the somatostatin analog lanreotide. | Cancer science 20071201 |
Role of CYP2E1 in diethylnitrosamine-induced hepatocarcinogenesis in vivo. | Cancer research 20071201 |
Diuron lacks promoting potential in a rat liver bioassay. | Toxicologic pathology 20071201 |
Low-level exposure to multiple chemicals: reason for human health concerns? | Environmental health perspectives 20071201 |
Promoting effect of o-aminoazotoluene on hepatocarcinogenesis is accompanied by the increase in inflammatory and proliferative processes in liver tissue and decrease in the concentration of free thyroxin in the blood. | Bulletin of experimental biology and medicine 20071201 |
Hepatocellular carcinoma and sex. | The New England journal of medicine 20071108 |
Anticarcinogenic effects of hexaamminecobalt(III) chloride in mice initiated with diethylnitrosamine. | Biological trace element research 20071101 |
Loss of hepatocyte growth factor/c-Met signaling pathway accelerates early stages of N-nitrosodiethylamine induced hepatocarcinogenesis. | Cancer research 20071015 |
Different mutation patterns of mitochondrial DNA displacement-loop in hepatocellular carcinomas induced by N-nitrosodiethylamine and a choline-deficient l-amino acid-defined diet in rats. | Biochemical and biophysical research communications 20071012 |
The effect of dietary glycine on the hepatic tumor promoting activity of polychlorinated biphenyls (PCBs) in rats. | Toxicology 20071008 |
Comparison of mode of action of four hepatocarcinogens: a model-based approach. | Toxicological sciences : an official journal of the Society of Toxicology 20071001 |
Prevention by melatonin of hepatocarcinogenesis in rats injected with N-nitrosodiethylamine. | Journal of pineal research 20071001 |
Is interleukin-6 a gender-specific risk factor for liver cancer? | Hepatology (Baltimore, Md.) 20071001 |
Chemo-preventive effect of Star anise in N-nitrosodiethylamine initiated and phenobarbital promoted hepato-carcinogenesis. | Chemico-biological interactions 20070920 |
Global gene expression in Ha-ras and B-raf mutated mouse liver tumors. | International journal of cancer 20070915 |
Evaluating the impacts of membrane type, coating, fouling, chemical properties and water chemistry on reverse osmosis rejection of seven nitrosoalklyamines, including NDMA. | Water research 20070901 |
Diethylnitrosamine initiation does not alter clofibric acid-induced hepatocarcinogenesis in the rat. | Toxicological sciences : an official journal of the Society of Toxicology 20070901 |
Proteome analysis of chemically induced mouse liver tumors with different genotype. | Proteomics 20070901 |
Changes in the antioxidant system by TNP-470 in an in vivo model of hepatocarcinoma. | Translational research : the journal of laboratory and clinical medicine 20070901 |
RB loss abrogates cell cycle control and genome integrity to promote liver tumorigenesis. | Gastroenterology 20070901 |
Enhancement of hepatocellular proliferative activity of kojic acid in mice by a simultaneous administration of ascorbic acid. | The Journal of veterinary medical science 20070901 |
Photochemical attenuation of N-nitrosodimethylamine (NDMA) and other nitrosamines in surface water. | Environmental science & technology 20070901 |
Effect of Qi-protecting powder (Huqi San) on expression of c-jun, c-fos and c-myc in diethylnitrosamine-mediated hepatocarcinogenesis. | World journal of gastroenterology 20070821 |
Hepatocytes isolated from preneoplastic rat livers are resistant to ethacrynic acid cytotoxicity. | Archives of toxicology 20070801 |
Chemotherapeutic stress selectively activates NF-kappa B-dependent AKT and VEGF expression in liver cancer-derived endothelial cells. | American journal of physiology. Cell physiology 20070801 |
DNA damage measured by comet assay and 8-OH-dG formation related to blood chemical analyses in aged rats. | The Journal of toxicological sciences 20070801 |
Both early and late stages of hepatocarcinogenesis are enhanced in Cx32 dominant negative mutant transgenic rats with disrupted gap junctional intercellular communication. | The Journal of membrane biology 20070801 |
Lutein presents suppressing but not blocking chemopreventive activity during diethylnitrosamine-induced hepatocarcinogenesis and this involves inhibition of DNA damage. | Chemico-biological interactions 20070720 |
Cell proliferation and hepatocarcinogenesis in rat initiated by diethylnitrosamine and promoted by phenobarbital: potential roles of early DNA damage and liver metallothionein expression. | Life sciences 20070719 |
Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production. | Science (New York, N.Y.) 20070706 |
Promoting potential of a Jamaica quassia extract in a rat medium-term hepatocarcinogenesis bioassay. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070701 |
Co-carcinogenic effect of cyclohexanol on the development of preneoplastic lesions in a rat hepatocarcinogenesis model. | Molecular carcinogenesis 20070701 |
Prevention of hepatocarcinogenesis with phosphatidylcholine and menaquinone-4: in vitro and in vivo experiments. | Journal of hepatology 20070701 |
Expression and DNA methylation patterns of Tslc1 and Dal-1 genes in hepatocellular carcinomas induced by N-nitrosodiethylamine in rats. | Cancer science 20070701 |
The PPARgamma agonist pioglitazone inhibits early neoplastic occurrence in the rat liver. | European journal of cancer (Oxford, England : 1990) 20070701 |
Hypoxia-inducible factor-1alpha expression in experimental cirrhosis: correlation with vascular endothelial growth factor expression and angiogenesis. | APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20070701 |
Investigating the mechanistic basis for hepatic toxicity induced by an experimental chemokine receptor 5 (CCR5) antagonist using a compendium of gene expression profiles. | Toxicologic pathology 20070601 |
Nitrosamines as nicotinic receptor ligands. | Life sciences 20070530 |
Molecular basis of vanadium-mediated inhibition of hepatocellular preneoplasia during experimental hepatocarcinogenesis in rats. | Journal of cellular biochemistry 20070501 |
Analysis of nitrosamines by capillary electrospray-high-field asymmetric waveform ion mobility spectrometry-MS with programmed compensation voltage. | Electrophoresis 20070501 |
Silymarin modulates the oxidant-antioxidant imbalance during diethylnitrosamine induced oxidative stress in rats. | European journal of pharmacology 20070410 |
Effect of Cassia fistula Linn. leaf extract on diethylnitrosamine induced hepatic injury in rats. | Chemico-biological interactions 20070405 |
Sodium iodide symporter is expressed at the preneoplastic stages of liver carcinogenesis and in human cholangiocarcinoma. | Gastroenterology 20070401 |
Possible application of human c-Ha-ras proto-oncogene transgenic rats in a medium-term bioassay model for carcinogens. | Toxicologic pathology 20070401 |
Impediment of diethylnitrosamine induced hepatotoxicity in male Balb/c mice by pretreatment with aqueous Azadirachta indica leaf extract. | Indian journal of experimental biology 20070401 |
Anti-Cripto Mab inhibit tumour growth and overcome MDR in a human leukaemia MDR cell line by inhibition of Akt and activation of JNK/SAPK and bad death pathways. | British journal of cancer 20070326 |
Increased 5-HT2C receptor binding in the brain stem and cerebral cortex during liver regeneration and hepatic neoplasia in rats. | Journal of the neurological sciences 20070315 |
Interfacial behavior of N-nitrosodiethylamine/bovine serum albumin complexes at the air-water and the chloroform-water interfaces by axisymmetric drop tensiometry. | The journal of physical chemistry. B 20070315 |
Cumulative genotoxic and apoptotic effects of xenobiotics in a mini organ culture model of human nasal mucosa as detected by the alkaline single cell microgel electrophoresis assay and the annexin V-affinity assay. | Toxicology letters 20070308 |
Orphan nuclear receptor constitutive active/androstane receptor-mediated alterations in DNA methylation during phenobarbital promotion of liver tumorigenesis. | Toxicological sciences : an official journal of the Society of Toxicology 20070301 |
Combined GM-CSF and IL-12 gene therapy synergistically suppresses the growth of orthotopic liver tumors. | Hepatology (Baltimore, Md.) 20070301 |
Expression of ErbB receptor proteins and TGF-alpha during diethylnitrosamine-induced hepatocarcinogenesis in the rat liver. | The Korean journal of hepatology 20070301 |
[Effect of 5 drugs with different antitumor mechanism on tumor-formation potential of rat hepatocarcinoma cells and mesenchymal stem cells]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20070301 |
Effect of silymarin on N-nitrosodiethylamine induced hepatocarcinogenesis in rats. | Experimental oncology 20070301 |
Assessment of hemodynamics in precancerous lesion of hepatocellular carcinoma: evaluation with MR perfusion. | World journal of gastroenterology 20070227 |
High sensitivity of fatty liver Shionogi (FLS) mice to diethylnitrosamine hepatocarcinogenesis: comparison to C3H and C57 mice. | Cancer letters 20070208 |
Coupling of lactose molecules to the carrier protein hinders the spleen and bone marrow uptake of doxorubicin conjugated with human albumin. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070201 |
Evaluation of the cancer chemopreventive efficacy of rice bran in genetic mouse models of breast, prostate and intestinal carcinogenesis. | British journal of cancer 20070129 |
A cell-penetrating ARF peptide inhibitor of FoxM1 in mouse hepatocellular carcinoma treatment. | The Journal of clinical investigation 20070102 |
Pravastatin reduces lung metastasis of rat hepatocellular carcinoma via a coordinated decrease of MMP expression and activity. | Journal of hepatology 20070101 |
Overexpression of cyclin D1 is associated with elevated levels of MAP kinases, Akt and Pak1 during diethylnitrosamine-induced progressive liver carcinogenesis. | Cell biology international 20070101 |
The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450-mediated biotransformation (a corrigendum report on Duarte et al. (2005) Mutagenesis 20, 93-100). | Mutagenesis 20070101 |
Carcinogen-induced early molecular events and its implication in the initiation of chemical hepatocarcinogenesis in rats: chemopreventive role of vanadium on this process. | Biochimica et biophysica acta 20070101 |
Hepatitis B virus promotes hepatocarcinogenesis in transgenic mice. | Hepatology (Baltimore, Md.) 20070101 |
Cell-cycle inhibition by TNP-470 in an in vivo model of hepatocarcinoma is mediated by a p53 and p21WAF1/CIP1 mechanism. | Translational research : the journal of laboratory and clinical medicine 20070101 |
Bioinformatics analysis of the early inflammatory response in a rat thermal injury model. | BMC bioinformatics 20070101 |
Effect of Bauhinia racemosa stem bark on N-nitrosodiethylamine-induced hepatocarcinogenesis in rats. | The American journal of Chinese medicine 20070101 |
Effect of Solanum trilobatum on hepatic drug metabolising enzymes during diethylnitrosamine-induced hepatocarcinogenesis promoted by Phenobarbital in rat. | Hepatology research : the official journal of the Japan Society of Hepatology 20070101 |
[Promoting effect of liver regeneration in hepatocarcinogenesis initiated by diethylnitrosamine in the rat]. | Pathologie-biologie 20070101 |
Persistent activation of NF-kappaB related to IkappaB's degradation profiles during early chemical hepatocarcinogenesis. | Journal of carcinogenesis 20070101 |
Angiogenic factor expression in hepatic cirrhosis. | Mediators of inflammation 20070101 |
MAK-4 and -5 supplemented diet inhibits liver carcinogenesis in mice. | BMC complementary and alternative medicine 20070101 |
Further studies on antioxidant potential and protection of pancreatic beta-cells by Embelia ribes in experimental diabetes. | Experimental diabetes research 20070101 |
The H19 non-coding RNA is essential for human tumor growth. | PloS one 20070101 |
Potential of Vinca rosea extracts in modulating trace element profile: a chemopreventive approach. | Biological trace element research 20070101 |
Evidence that proteasome-dependent degradation of the retinoblastoma protein in cells lacking A-type lamins occurs independently of gankyrin and MDM2. | PloS one 20070101 |
Effects of acetylsalicylic acid and celecoxib on the N-nitrosodiethylamine induced carcinogenesis in rat liver and esophagus. | Bulletin of experimental biology and medicine 20070101 |
Effect of melatonin on N-nitrosodiethylamine-induced hepatocarcinogenesis in rats with reference to biochemical circadian rhythms. | Toxicology mechanisms and methods 20070101 |
Influence of diallyl disulphide on temporal patterns of circulatory lipid peroxidation products and antioxidants in N-nitrosodiethylamine-induced hepatocarcinogenesis in rats. | Toxicology mechanisms and methods 20070101 |
Transplantation of fetal liver epithelial progenitor cells ameliorates experimental liver fibrosis in mice. | World journal of gastroenterology 20061207 |
Altered gene expression of transcriptional regulatory factors in tumor marker-positive cells during chemically induced hepatocarcinogenesis. | Toxicology letters 20061201 |
Antiangiogenic effect of Lygodium flexuosum against N-nitrosodiethylamine-induced hepatotoxicity in rats. | Chemico-biological interactions 20061201 |
Chemoprevention of bicyclol against hepatic preneoplastic lesions. | Cancer biology & therapy 20061201 |
The oncofetal protein glypican-3 is a novel marker of hepatic progenitor/oval cells. | Laboratory investigation; a journal of technical methods and pathology 20061201 |
In vivo 1H MR spectroscopy in the evaluation of the serial development of hepatocarcinogenesis in an experimental rat model. | Academic radiology 20061201 |
Why cancer and inflammation? | The Yale journal of biology and medicine 20061201 |
A single dose of caffeic acid phenethyl ester prevents initiation in a medium-term rat hepatocarcinogenesis model. | World journal of gastroenterology 20061114 |
Mutagenicity of cytochrome P450 2E1 substrates in the Ames test with the metabolic competent S. typhimurium strain YG7108pin3ERb5. | Toxicology 20061110 |
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. | Journal of molecular graphics & modelling 20061101 |
Molecular basis of anticlastogenic potential of vanadium in vivo during the early stages of diethylnitrosamine-induced hepatocarcinogenesis in rats. | Mutation research 20061030 |
Chemopreventive effect of vanadium in a rodent model of chemical hepatocarcinogenesis: reflections in oxidative DNA damage, energy-dispersive X-ray fluorescence profile and metallothionein expression. | Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20061001 |
Vanadium limits the expression of proliferating cell nuclear antigen and inhibits early DNA damage during diethylnitrosamine-induced hepatocellular preneoplasia in rats. | Environmental and molecular mutagenesis 20061001 |
Metabolic normalization of alpha-ketoglutarate against N-nitrosodiethylamine-induced hepatocarcinogenesis in rats. | Fundamental & clinical pharmacology 20061001 |
Evaluation of possible mechanisms of protective role of Tamarix gallica against DEN initiated and 2-AAF promoted hepatocarcinogenesis in male Wistar rats. | Life sciences 20060905 |
PCB 153, a non-dioxin-like tumor promoter, selects for beta-catenin (Catnb)-mutated mouse liver tumors. | Toxicological sciences : an official journal of the Society of Toxicology 20060901 |
Key issues in the modes of action and effects of trichloroethylene metabolites for liver and kidney tumorigenesis. | Environmental health perspectives 20060901 |
Key issues in the role of peroxisome proliferator-activated receptor agonism and cell signaling in trichloroethylene toxicity. | Environmental health perspectives 20060901 |
[A relationship between cyclooxygenase-2 expression and tumor angiogenesis in experimental rat liver carcinogenesis]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20060901 |
Alpha-benzene hexachloride exerts hormesis in preneoplastic lesion formation of rat hepatocarcinogenesis with the possible role for hepatic detoxifying enzymes. | Cancer letters 20060818 |
Ablation of gap junctional communication in hepatocytes of transgenic mice does not lead to disrupted cellular homeostasis or increased spontaneous tumourigenesis. | European journal of cell biology 20060801 |
High volume hydrodynamic injection of plasmid DNA via the hepatic artery results in a high level of gene expression in rat hepatocellular carcinoma induced by diethylnitrosamine. | The journal of gene medicine 20060801 |
A conjugate of doxorubicin with lactosaminated albumin enhances the drug concentrations in all the forms of rat hepatocellular carcinomas independently of their differentiation grade. | Liver international : official journal of the International Association for the Study of the Liver 20060801 |
[Correlation of antitumor drug sensitivity between marrow mesenchymal stem cells (MSCs) and hepatocarcinoma cells in rats]. | Ai zheng = Aizheng = Chinese journal of cancer 20060801 |
Inactivation of PEMT2 in hepatocytes initiated by DENA in fasted/refed rats. | Biochemical and biophysical research communications 20060721 |
Expression of GCIP in transgenic mice decreases susceptibility to chemical hepatocarcinogenesis. | Oncogene 20060713 |
Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation. | Proceedings of the National Academy of Sciences of the United States of America 20060711 |
Tumor promoting potency of PCBs 28 and 101 in rat liver. | Toxicology letters 20060701 |
Assessment of chronic toxicity and carcinogenicity in an accelerated cancer bioassay in rats of Nifurtimox, an antitrypanosomiasis drug. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20060701 |
Deletion of the SOCS3 gene in liver parenchymal cells promotes hepatitis-induced hepatocarcinogenesis. | Gastroenterology 20060701 |
[Malignant tendency of basophilic liver cells in experimental rat hepatocarcinogenesis]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20060701 |
Critique of dose response in carcinogenesis. | Human & experimental toxicology 20060701 |
Adenovirus vector-mediated gene transfer using degradable starch microspheres for hepatocellular carcinoma in rats. | The Journal of surgical research 20060615 |
Suppression of N-nitrosodiethylamine induced hepatocarcinogenesis by silymarin in rats. | Chemico-biological interactions 20060610 |
Evaluation of nitroreductase and acetyltransferase participation in N-nitrosodiethylamine genotoxicity. | Chemico-biological interactions 20060610 |
Concordance of thresholds for carcinogenicity of N-nitrosodiethylamine. | Archives of toxicology 20060601 |
Protective effects of guarana (Paullinia cupana Mart. var. Sorbilis) against DEN-induced DNA damage on mouse liver. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060601 |
In vivo detection of free radicals induced by diethylnitrosamine in rat liver tissue. | Free radical biology & medicine 20060601 |
Possible tumor development from double positive foci for TGF-alpha and GST-P observed in early stages on rat hepatocarcinogenesis. | Cancer science 20060601 |
Enhancing effects of simultaneous treatment with sodium nitrite on 2-amino-3-methylimidazo[4,5-f]quinoline-induced rat liver, colon and Zymbal's gland carcinogenesis after initiation with diethylnitrosamine and 1,2-dimethylhydrazine. | International journal of cancer 20060515 |
Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
Gradual upregulation of OCI-5 expression during occurrence and progression of rat hepatocellular carcinoma. | Hepatobiliary & pancreatic diseases international : HBPD INT 20060501 |
[The biological behavior of hepatocarcinoma stem cells in rats]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20060501 |
Etiology of bromate-induced cancer and possible modes of action-studies in Japan. | Toxicology 20060417 |
Essential contribution of a chemokine, CCL3, and its receptor, CCR1, to hepatocellular carcinoma progression. | International journal of cancer 20060415 |
Kinetics and mechanisms of the reactions of hydroxyl radicals and hydrated electrons with nitrosamines and nitramines in water. | The journal of physical chemistry. A 20060413 |
Effect of selenium-enriched malt on hepatocarcinogenesis, paraneoplastic syndrome and the hormones regulating blood glucose in rats treated by diethylnitrosamine. | Life sciences 20060411 |
Chemoprevention and cytotoxic effect of Bauhinia variegata against N-nitrosodiethylamine induced liver tumors and human cancer cell lines. | Journal of ethnopharmacology 20060406 |
Inhibition of hepatocarcinogenesis by the deletion of the p50 subunit of NF-kappaB in mice administered the peroxisome proliferator Wy-14,643. | Toxicological sciences : an official journal of the Society of Toxicology 20060401 |
Early induction of TGF-beta1 through a fasting-re-feeding regimen promotes liver carcinogenesis by a sub-initiating dose of diethylnitrosamine. | Cell proliferation 20060401 |
Genotoxicity of glycidamide in comparison to (+/-)-anti-benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide and alpha-acetoxy-N-nitroso-diethanolamine in human blood and in mammalian V79-cells. | Molecular nutrition & food research 20060401 |
Halofuginone suppresses the lung metastasis of chemically induced hepatocellular carcinoma in rats through MMP inhibition. | Neoplasia (New York, N.Y.) 20060401 |
[Induction of chemical hepatocarcinogenesis and establishment of orthotopic liver transplantation model with hepatocarcinoma in rats]. | Zhonghua yi xue za zhi 20060328 |
Transplantable tumor lines generated in clonal zebrafish. | Cancer research 20060315 |
Effects of administration of Embelin and Curcumin on lipid peroxidation, hepatic glutathione antioxidant defense and hematopoietic system during N-nitrosodiethylamine/Phenobarbital-induced hepatocarcinogenesis in Wistar rats. | Molecular and cellular biochemistry 20060301 |
Chemopreventive effects of Paullinia cupana Mart var. sorbilis, the guaraná, on mouse hepatocarcinogenesis. | Cancer letters 20060220 |
Ectopic activity of fibroblast growth factor receptor 1 in hepatocytes accelerates hepatocarcinogenesis by driving proliferation and vascular endothelial growth factor-induced angiogenesis. | Cancer research 20060201 |
A dual and opposite effect of Calendula officinalis flower extract: chemoprotector and promoter in a rat hepatocarcinogenesis model. | Planta medica 20060201 |
Nine-week detection of six genotoxic lung carcinogens using the rasH2/BHT mouse model. | Cancer letters 20060118 |
Amelioration of carcinogenesis and tumor growth in the rat liver by combination of vitamin K2 and angiotensin-converting enzyme inhibitor via anti-angiogenic activities. | Oncology reports 20060101 |
Antioxidant activity of Terminalia arjuna bark extract on N-nitrosodiethylamine induced hepatocellular carcinoma in rats. | Molecular and cellular biochemistry 20060101 |
Pronounced inhibitory effect of chlorcyclizine (CCZ) in experimental hepatocarcinoma. | In vivo (Athens, Greece) 20060101 |
Research needs in drinking water: a basis in regulations in the United States. | Journal of water and health 20060101 |
N-nitrosodiethylamine-induced pig liver hepatocellular carcinoma model: radiological and histopathological studies. | Cardiovascular and interventional radiology 20060101 |
Alpha-ketoglutarate modulates the circadian patterns of lipid peroxidation and antioxidant status during N-nitrosodiethylamine-induced hepatocarcinogenesis in rats. | Journal of medicinal food 20060101 |
Effects of cessation of alcohol exposure on rat hepatocarcinogenesis. | Asian Pacific journal of cancer prevention : APJCP 20060101 |
Catheterization of the hepatic artery via the left common carotid artery in rats. | Cardiovascular and interventional radiology 20060101 |
A long-term investigation of the anti-hepatocarcinogenic potential of an indigenous medicine comprised of Nigella sativa, Hemidesmus indicus and Smilax glabra. | Journal of carcinogenesis 20060101 |
Lack of promoting effects of phenobarbital at low dose on diethylnitrosamine-induced hepatocarcinogenesis in TGF-alpha transgenic mice. | Asian Pacific journal of cancer prevention : APJCP 20060101 |
Impact of hypercholesterolemia on toxicity of N-nitrosodiethylamine: biochemical and histopathological effects. | Pharmacological reports : PR 20060101 |
Chemopreventive activity of a macrofungus Phellinus rimosus against N-nitrosodiethylamine induced hepatocellular carcinoma in rat. | Journal of experimental therapeutics & oncology 20060101 |
IGF-II transgenic mice display increased aberrant colon crypt multiplicity and tumor volume after 1,2-dimethylhydrazine treatment. | Journal of carcinogenesis 20060101 |
Phytotherapeutic compound YHK exerts an inhibitory effect on early stage of experimentally-induced neoplastic liver lesions. | Annals of hepatology 20060101 |
Gene expression analysis on the dicyclanil-induced hepatocellular tumors in mice. | Toxicologic pathology 20060101 |
Bone disorders in experimentally induced liver disease in growing rats. | World journal of gastroenterology 20051207 |
[Mini-organ cultures of human nasal mucosa. A model for eco-genotoxicological investigations]. | HNO 20051201 |
Species-specific effects of the hepatocarcinogens 3'-methyl-4-dimethyl-aminoazobenzene and ortho-aminoazotoluene in mouse and rat liver. | Molecular carcinogenesis 20051201 |
The inhibitory effect of sodium selenite on N-nitrosodiethylamine-induced and phenobarbital promoted liver tumourigenesis in rats based on the modulation of polyamine levels. | Molecular and cellular biochemistry 20051201 |
Role of HSP90, CDC37, and CRM1 as modulators of P16(INK4A) activity in rat liver carcinogenesis and human liver cancer. | Hepatology (Baltimore, Md.) 20051201 |
[Effect of phenobarbital and thyroxine on hepatocarcinogenesis initiated in mice by nitrosoethylurea and diethylnitrosamine]. | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20051201 |
CCAAT/enhancer binding protein alpha knock-in mice exhibit early liver glycogen storage and reduced susceptibility to hepatocellular carcinoma. | Cancer research 20051115 |
Low dose DDT inhibition of hepatocarcinogenesis initiated by diethylnitrosamine in male rats: possible mechanisms. | Toxicology and applied pharmacology 20051101 |
Occurrence of N-nitrosodimethylamine in South Korean and imported alcoholic beverages. | Food additives and contaminants 20051101 |
Protective role of Vitamin E pre-treatment on N-nitrosodiethylamine induced oxidative stress in rat liver. | Chemico-biological interactions 20051020 |
Effect of Solanum trilobatum on the antioxidant status during diethyl nitrosamine induced and phenobarbital promoted hepatocarcinogenesis in rat. | Chemico-biological interactions 20051020 |
Investigation of the formation of N-nitrosodiethanolamine in B6C3F1 mice following topical administration of triethanolamine. | Regulatory toxicology and pharmacology : RTP 20051001 |
Human p53 knock-in (hupki) mice do not differ in liver tumor response from their counterparts with murine p53. | Carcinogenesis 20051001 |
Doxorubicin coupled to lactosaminated albumin inhibits the growth of hepatocellular carcinomas induced in rats by diethylnitrosamine. | Journal of hepatology 20051001 |
NDELA and nickel modulation of triazine disposition in skin. | Toxicology and industrial health 20051001 |
Apigenin inhibits oxidative stress-induced macromolecular damage in N-nitrosodiethylamine (NDEA)-induced hepatocellular carcinogenesis in Wistar albino rats. | Molecular carcinogenesis 20050901 |
In vivo detection of metabolic changes by 1H-MRS in the DEN-induced hepatocellular carcinoma in Wistar rat. | Journal of cancer research and clinical oncology 20050901 |
Chemopreventive effects of embelin and curcumin against N-nitrosodiethylamine/phenobarbital-induced hepatocarcinogenesis in Wistar rats. | Fitoterapia 20050901 |
Overexpression of insulin receptor substrate-2 in human and murine hepatocellular carcinoma. | The American journal of pathology 20050901 |
Assessing susceptibility from early-life exposure to carcinogens. | Environmental health perspectives 20050901 |
Inhibitory effects of Pfaffia paniculata (Brazilian ginseng) on preneoplastic and neoplastic lesions in a mouse hepatocarcinogenesis model. | Cancer letters 20050826 |
Melatonin modulates the oxidant-antioxidant imbalance during N-nitrosodiethylamine induced hepatocarcinogenesis in rats. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20050812 |
Altered retinoid metabolism in female Long-Evans and Han/Wistar rats following long-term 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-treatment. | Toxicological sciences : an official journal of the Society of Toxicology 20050801 |
Enhanced uptake of lactosaminated human albumin by rat hepatocarcinomas: implications for an improved chemotherapy of primary liver tumors. | Liver international : official journal of the International Association for the Study of the Liver 20050801 |
Suppression of beta-catenin mutation by dietary exposure of auraptene, a citrus antioxidant, in N,N-diethylnitrosamine-induced hepatocellular carcinomas in rats. | Oncology reports 20050801 |
Suppression of chemically-induced liver tumors by castration or estradiol-3-benzoate treatment in F344 rats. | Oncology reports 20050801 |
Suppression of glutathione S-transferase placental form-positive foci development in rat hepatocarcinogenesis by Chlorella pyrenoidosa. | Oncology reports 20050801 |
Roxithromycin inhibits constitutive activation of nuclear factor {kappa}B by diminishing oxidative stress in a rat model of hepatocellular carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050801 |
Magnetic resonance imaging of hepatocellular carcinoma induced by diethylnitrosamine in Sprague-Dawley rats. | Hepatobiliary & pancreatic diseases international : HBPD INT 20050801 |
Chemomodulatory effect of Ficus racemosa extract against chemically induced renal carcinogenesis and oxidative damage response in Wistar rats. | Life sciences 20050729 |
Decreased density of beta1-adrenergic receptors in preneoplastic and neoplastic liver lesions of F344 rats. | Histology and histopathology 20050701 |
IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis. | Cell 20050701 |
[Evaluation of early stage diffused liver lesions with MR functional diffusion-weighted imaging--an experimental study]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20050701 |
CT perfusion at early stage of hepatic diffuse disease. | World journal of gastroenterology 20050614 |
Automated solid-phase extraction and high-performance liquid chromatographic determination of nitrosamines using post-column photolysis and tris(2,2'-bipyridyl) ruthenium(III) chemiluminescence. | Journal of chromatography. A 20050603 |
Altered expression of cytochrome P450 and possible correlation with preneoplastic changes in early stage of rat hepatocarcinogenesis. | Acta pharmacologica Sinica 20050601 |
Increased lung metastasis in transgenic NM23-Null/SV40 mice with hepatocellular carcinoma. | Journal of the National Cancer Institute 20050601 |
Farnesyltransferase inhibitor, ABT-100, is a potent liver cancer chemopreventive agent. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050601 |
Modulation of N-nitrosodiethylamine (NDEA) induced oxidative stress by vitamin E in rat erythrocytes. | Human & experimental toxicology 20050601 |
Comparisons of thresholds for carcinogenicity on linear and logarithmic dosage scales. | Human & experimental toxicology 20050601 |
Effect of neonatal injection of sodium glutamate and diethylnitrosamine on hepatocarcinogenesis, reproductive and adrenocortical systems of male mice. | Bulletin of experimental biology and medicine 20050601 |
Apoptosis in stages of mouse hepatocarcinogenesis: failure to counterbalance cell proliferation and to account for strain differences in tumor susceptibility. | Toxicological sciences : an official journal of the Society of Toxicology 20050501 |
Interferon-gamma-mediated hepatocarcinogenesis in mice treated with diethylnitrosamine. | Laboratory investigation; a journal of technical methods and pathology 20050501 |
Escherichia coli BTC, a human cytochrome P450 competent tester strain with a high sensitivity towards alkylating agents: involvement of alkyltransferases in the repair of DNA damage induced by aromatic amines. | Mutagenesis 20050501 |
Deletion of Bid impedes cell proliferation and hepatic carcinogenesis. | The American journal of pathology 20050501 |
[In vivo micronuclei and gene mutation induced by DEN in the lacZ transgenic mouse]. | Wei sheng yan jiu = Journal of hygiene research 20050501 |
[Sodium glutamate on some physiological features and chemically induced hepatocarcinogenesis in neontal period in male mice]. | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20050501 |
Magnetic resonance diffusion-weighted imaging in the diagnosis of diffuse liver diseases in rats. | Chinese medical journal 20050420 |
Inhibitory effect of celery seeds extract on chemically induced hepatocarcinogenesis: modulation of cell proliferation, metabolism and altered hepatic foci development. | Cancer letters 20050418 |
AFP gene expression after acute diethylnitrosamine intoxication is not Afr2 regulated. | Cancer letters 20050408 |
Characterization of an acute molecular marker of nongenotoxic rodent hepatocarcinogenesis by gene expression profiling in a long term clofibric acid study. | Chemical research in toxicology 20050401 |
Different inhibitory effects in the early and late phase of treatment with KAT-681, a liver-selective thyromimetic, on rat hepatocarcinogenesis induced by 2-acetylaminofluorene and partial hepatectomy after diethylnitrosamine initiation. | Toxicological sciences : an official journal of the Society of Toxicology 20050301 |
HMG-CoA reductase inhibitors, statins, induce phosphorylation of Mdm2 and attenuate the p53 response to DNA damage. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050301 |
Combination of interferon and angiotensin-converting enzyme inhibitor, perindopril, suppresses liver carcinogenesis and angiogenesis in mice. | Oncology reports 20050301 |
Hepatitis C virus acts as a tumor accelerator by blocking apoptosis in a mouse model of hepatocarcinogenesis. | Hepatology (Baltimore, Md.) 20050301 |
The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450 mediated biotransformation. | Mutagenesis 20050301 |
Mass spectrometric methodology for the determination of glyoxaldeoxyguanosine and O6-hydroxyethyldeoxyguanosine DNA adducts produced by nitrosamine bident carcinogens. | Chemical research in toxicology 20050301 |
Efficacy of Terminalia arjuna (Roxb.) on N-nitrosodiethylamine induced hepatocellular carcinoma in rats. | Indian journal of experimental biology 20050301 |
Radiomodulatory effect of liposome encapsulated AK-2123 on tumor in mice exposed to hepatocarcinogen. | Molecular and cellular biochemistry 20050301 |
Downregulation of apoptosis revealed by laser microdissection and cDNA microarray analysis of related genes in rat liver preneoplastic lesions. | Medical molecular morphology 20050301 |
Modulation of liver tumorigenesis in Connexin32-deficient mouse. | Mutation research 20050215 |
Fumagillin treatment of hepatocellular carcinoma in rats: an in vivo study of antiangiogenesis. | World journal of gastroenterology 20050214 |
B-raf and Ha-ras mutations in chemically induced mouse liver tumors. | Oncogene 20050210 |
Superoxide generation from Kupffer cells contributes to hepatocarcinogenesis: studies on NADPH oxidase knockout mice. | Carcinogenesis 20050201 |
Gefitinib, an EGFR inhibitor, prevents hepatocellular carcinoma development in the rat liver with cirrhosis. | Hepatology (Baltimore, Md.) 20050201 |
Determination of N-nitrosodiethanolamine in cosmetic products by LC-MS-MS. | Analytical and bioanalytical chemistry 20050201 |
Chemoprevention of N-nitrosodiethylamine induced phenobarbitol promoted liver tumors in rat by extract of Indigofera aspalathoides. | Biological & pharmaceutical bulletin 20050201 |
[Pexoxisome proliferator-activated receptor gamma ligands suppress liver carcinogenesis induced by diethylnitrosamine in rats]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20050201 |
Comparison of different initiation protocols in the resistant hepatocyte model. | Toxicology 20050131 |
Oxidative stress in carcinogenesis. Correlation between lipid peroxidation and induction of preneoplastic lesions in rat hepatocarcinogenesis. | Cancer letters 20050110 |
TCDD activates Mdm2 and attenuates the p53 response to DNA damaging agents. | Carcinogenesis 20050101 |
Evaluation of mutant frequencies of chemically induced tumors and normal tissues in lambda/cII transgenic mice. | Environmental and molecular mutagenesis 20050101 |
Inhibition of lung tumorigenesis by tea. | Experimental lung research 20050101 |
Dietary administration of inositol and/or inositol-6-phosphate prevents chemically-induced rat hepatocarcinogenesis. | Asian Pacific journal of cancer prevention : APJCP 20050101 |
Effect of proapoptosis protein on hepatocarcinogenesis. | Chinese journal of digestive diseases 20050101 |
Characterization of insulin-like-growth factor II (IGF II) mRNA positive hepatic altered foci and IGF II expression in hepatocellular carcinoma during diethylnitrosamine-induced hepatocarcinogenesis in rats. | Journal of carcinogenesis 20050101 |
Suppression of renin-angiotensin system attenuates hepatocarcinogenesis via angiogenesis inhibition in rats. | Anticancer research 20050101 |
Targeting energy metabolism in brain cancer: review and hypothesis. | Nutrition & metabolism 20050101 |
Transgenic disruption of gap junctional intercellular communication enhances early but not late stage hepatocarcinogenesis in the rat. | Toxicologic pathology 20050101 |
Total antioxidant status in the blood serum of rats exposed to N-nitroso compounds and nitric oxide synthase inhibitors. | Roczniki Panstwowego Zakladu Higieny 20050101 |
Evaluation of the carcinogenic potential of clofibrate in the neonatal mouse. | International journal of toxicology 20050101 |
Modification of an in vivo lung metastasis model of hepatocellular carcinoma by low dose N-nitrosomorpholine and diethylnitrosamine. | Clinical & experimental metastasis 20050101 |
A new experimental model to study preneoplastic lesions in achalasia of the esophagus. | Acta cirurgica brasileira 20050101 |
[Ratio of low- and high-spin cytochrome P-450 in liver microsomes of N-nitrosodiethylamine-induced hepatomas]. | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20050101 |
Altered tumor biology and tumorigenesis in irradiated and chemical carcinogen-treated single and combined connexin32/p27Kip1-deficient mice. | Cell communication & adhesion 20050101 |
[Development of a rat model for primary liver cancer with modified method]. | Zhonghua yi xue za zhi 20041202 |
Participation of BER and NER pathways in the repair of DNA lesions induced at low N-nitrosodiethylamine concentrations. | Toxicology letters 20041201 |
Peroxisome proliferator-activated receptor gamma ligands suppress liver carcinogenesis induced by diethylnitrosamine in rats. | World journal of gastroenterology 20041201 |
Suppression of diethylnitrosamine and 2-acetylaminofluorene-induced hepatocarcinogenesis in rats by tocotrienol-rich fraction isolated from rice bran oil. | European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20041201 |
Application of comparative functional genomics to identify best-fit mouse models to study human cancer. | Nature genetics 20041201 |
Inherent growth advantage of (pre)malignant hepatocytes associated with nuclear translocation of pro-transforming growth factor alpha. | British journal of cancer 20041129 |
Lack of antagonism of 2,3,7,8-tetrachlorodibenzo-p-dioxin's (TCDDs) induction of cytochrome P4501A1 (CYP1A1) by the putative selective aryl hydrocarbon receptor modulator 6-alkyl-1,3,8-trichlorodibenzofuran (6-MCDF) in the mouse hepatoma cell line Hepa-1c1c7. | Chemico-biological interactions 20041120 |
alpha(2)-Macroglobulin: a novel cytochemical marker characterizing preneoplastic and neoplastic rat liver lesions negative for hitherto established cytochemical markers. | The American journal of pathology 20041101 |
Long-term radioiodine retention and regression of liver cancer after sodium iodide symporter gene transfer in wistar rats. | Cancer research 20041101 |
Further development of 32P-postlabeling for the detection of alkylphosphotriesters: evidence for the long-term nonrandom persistence of ethyl-phosphotriester adducts in vivo. | Chemical research in toxicology 20041101 |
A modified rat model for hepatocellular carcinoma. | Hepatobiliary & pancreatic diseases international : HBPD INT 20041101 |
The gap junction protein connexin32 is a mouse lung tumor suppressor. | Cancer research 20041015 |
The orphan nuclear receptor constitutive active/androstane receptor is essential for liver tumor promotion by phenobarbital in mice. | Cancer research 20041015 |
Absence of carcinogenic and anticarcinogenic effects of annatto in the rat liver medium-term assay. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20041001 |
Dietary modulation of fatty acid profiles and oxidative status of rat hepatocyte nodules: effect of different n-6/n-3 fatty acid ratios. | Lipids 20041001 |
In vivo antioxidant potential of rice bran oil (RBO) in albino rats. | Indian journal of physiology and pharmacology 20041001 |
Enhancement of hepatocarcinogenesis by kojic acid in rat two-stage models after initiation with N-bis(2-hydroxypropyl)nitrosamine or N-diethylnitrosamine. | Toxicological sciences : an official journal of the Society of Toxicology 20040901 |
Post-initiation modulating effects of allyl sulfides in rat hepatocarcinogenesis. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040901 |
Induction of preneoplastic rat liver lesions with an attenuated p53 response by low doses of diethylnitrosamine. | Archives of toxicology 20040901 |
Inhibitory effects of KAT-681, a liver-selective thyromimetic, on development of hepatocellular proliferative lesions in rats induced by 2-acetylaminofluorene and partial hepatectomy after diethylnitrosamine initiation. | Archives of toxicology 20040801 |
Age-related differences in susceptibility to carcinogenesis: a quantitative analysis of empirical animal bioassay data. | Environmental health perspectives 20040801 |
Interferon alpha-induced apoptosis on rat preneoplastic liver is mediated by hepatocytic transforming growth factor beta(1). | Hepatology (Baltimore, Md.) 20040801 |
Modulation of altered hepatic foci induction by diallyl sulphide in Wistar rats. | European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20040801 |
Disruption of sphingolipid biosynthesis in hepatocyte nodules: selective proliferative stimulus induced by fumonisin B1. | Toxicology 20040715 |
Differentiation processes of oval cells into hepatocytes: proposals based on morphological and phenotypical traits in carcinogen-treated hamster liver. | Journal of comparative pathology 20040701 |
Aryl hydrocarbon receptor (AhR)-independent effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on softshell clam (Mya arenaria) reproductive tissue. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20040701 |
Standardization of conditions for the metabolic activation of N-nitrosodiethylamine in mutagenicity tests. | Genetics and molecular research : GMR 20040630 |
An acyclic retinoid, NIK-333, inhibits N-diethylnitrosamine-induced rat hepatocarcinogenesis through suppression of TGF-alpha expression and cell proliferation. | Carcinogenesis 20040601 |
Bone marrow engraftment in a rodent model of chemical carcinogenesis but no role in the histogenesis of hepatocellular carcinoma. | Gut 20040601 |
Combined supplementation of vanadium and beta-carotene suppresses placental glutathione S-transferase-positive foci and enhances antioxidant functions during the inhibition of diethylnitrosamine-induced rat liver carcinogenesis. | Journal of gastroenterology and hepatology 20040601 |
Expression of cytochrome P4502E1 gene in hepatocellular carcinoma. | World journal of gastroenterology 20040601 |
Halting the interaction between vascular endothelial growth factor and its receptors attenuates liver carcinogenesis in mice. | Hepatology (Baltimore, Md.) 20040601 |
Relationship between high sensitivity of suckling mice to hepatocarcinogenic and antiglucocorticoid effects of o-aminoazotoluene and diethylnitrosamine. | Bulletin of experimental biology and medicine 20040601 |
Initiating activity of 4-chlorobiphenyl metabolites in the resistant hepatocyte model. | Toxicological sciences : an official journal of the Society of Toxicology 20040501 |
1alpha, 25-dihydroxyvitamin D3 prevents DNA damage and restores antioxidant enzymes in rat hepatocarcinogenesis induced by diethylnitrosamine and promoted by phenobarbital. | World journal of gastroenterology 20040501 |
Induction of preneoplastic altered hepatic foci following dietary sulphur supplementation. | Human & experimental toxicology 20040501 |
Heterozygous p53-deficient (+/-) mice develop fewer p53-negative preneoplastic focal liver lesions in response to treatment with diethylnitrosamine than do wild-type (+/+) mice. | Cancer letters 20040430 |
Delayed liver regeneration and increased susceptibility to chemical hepatocarcinogenesis in transgenic mice expressing a dominant-negative mutant of connexin32 only in the liver. | Carcinogenesis 20040401 |
Alterations of the M6p/Igf2 receptor gene in hepatocellular carcinomas induced by N-nitrosodiethylamine and a choline-deficient L-amino acid-defined diet in rats. | Molecular carcinogenesis 20040401 |
Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor. | Genes & development 20040401 |
Role of apoptosis for mouse liver growth regulation and tumor promotion: comparative analysis of mice with high (C3H/He) and low (C57Bl/6J) cancer susceptibility. | Toxicology letters 20040401 |
Analysis of thresholds for carcinogenicity. | Toxicology letters 20040401 |
Revised rat multi-organ carcinogenesis bioassay for whole-body detection of chemopreventive agents: modifying potential of S-methylcysteine. | Cancer letters 20040331 |
Disseminated tumor cells homing into rats' liver: a new possible mechanism of HCC recurrence. | World journal of gastroenterology 20040315 |
IFN-alpha prevents the growth of pre-neoplastic lesions and inhibits the development of hepatocellular carcinoma in the rat. | Carcinogenesis 20040301 |
Specific differences in gene expression profile revealed by cDNA microarray analysis of glutathione S-transferase placental form (GST-P) immunohistochemically positive rat liver foci and surrounding tissue. | Carcinogenesis 20040301 |
Inhibition of liver carcinogenesis in Wistar rats by consumption of an aqueous extract from leaves of Ardisia compressa. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040301 |
Preventive effect of Ganfujian granule on experimental hepatocarcinoma in rats. | World journal of gastroenterology 20040301 |
Transgenic mice expressing hepatitis B virus X protein are more susceptible to carcinogen induced hepatocarcinogenesis. | Experimental and molecular pathology 20040201 |
Rapid analysis of gene expression changes caused by liver carcinogens and chemopreventive agents using a newly developed three-dimensional microarray system. | Cancer science 20040201 |
Resveratrol inhibits N-nitrosodiethylamine-induced ornithine decarboxylase and cyclooxygenase in mice. | Journal of nutritional science and vitaminology 20040201 |
Chemically induced immunotoxicity in a medium-term multiorgan bioassay for carcinogenesis with Wistar rats. | Toxicology and applied pharmacology 20040115 |
Characterizing the role of MDM2 in diethylnitrosamine induced acute liver damage and development of pre-neoplastic lesions. | Carcinogenesis 20040101 |
Suppression of metastasis by nuclear factor kappaB inhibitors in an in vivo lung metastasis model of chemically induced hepatocellular carcinoma. | Cancer science 20040101 |
Effect of cacao liquor extract on tumor marker enzymes during chemical hepatocarcinogenesis in rats. | Journal of medicinal food 20040101 |
A liver micronucleus assay using young rats exposed to diethylnitrosamine: methodological establishment and evaluation. | Cytogenetic and genome research 20040101 |
Liver-specific expression of the agouti gene in transgenic mice promotes liver carcinogenesis in the absence of obesity and diabetes. | Molecular cancer 20040101 |
Protective role of Apigenin on the status of lipid peroxidation and antioxidant defense against hepatocarcinogenesis in Wistar albino rats. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20040101 |
High dietary intake of sodium selenite induces oxidative DNA damage in rat liver. | Nutrition and cancer 20040101 |
Dietary supplementation of the citrus antioxidant auraptene inhibits N,N-diethylnitrosamine-induced rat hepatocarcinogenesis. | Oncology 20040101 |
Antioxidant-associated chemoprevention by sodium selenite in N-nitrosodiethylamine-induced and phenobarbital-promoted hepatocarcinogenesis in rats. | Cell biochemistry and function 20040101 |
Thresholds for the effects of 2-acetylaminofluorene in rat liver. | Toxicologic pathology 20040101 |
The unknown nuclear protein that decreases HNF3 activity ensures species specificity of action of hepatocarcinogenic amino azo dyes. | Doklady. Biochemistry and biophysics 20040101 |
Potential anticancer effect of red spinach (Amaranthus gangeticus) extract. | Asia Pacific journal of clinical nutrition 20040101 |
Infiltrating CD8+ T lymphocytes, natural killer cells, and expression of IL-10 and TGF-beta1 in chemically induced neoplasms in male Wistar rats. | Toxicologic pathology 20040101 |
Chemopreventive effect of indole-3-carbinol on induction of preneoplastic altered hepatic foci. | Nutrition and cancer 20040101 |
Genetics of tobacco use. | Tobacco induced diseases 20040101 |
N-nitrosodiethanolamine. | Report on carcinogens : carcinogen profiles 20040101 |
N-Nitrosodiethylamine. | Report on carcinogens : carcinogen profiles 20040101 |
Heterologous expression of human cytochrome P450 2E1 in HepG2 cell line. | World journal of gastroenterology 20031215 |
Photochemistry of 1-(N,N-diethylamino)diazen-1-ium-1,2-diolate: an experimental and computational investigation. | Journal of the American Chemical Society 20031203 |
Reduced hepatocyte proliferation is the basis of retarded liver tumor progression and liver regeneration in mice lacking N-acetylglucosaminyltransferase III. | Cancer research 20031115 |
N-Nitrosodiethylamine mutagenicity at low concentrations. | Toxicology letters 20031101 |
Chemoprevention of preneoplastic liver foci development by dietary mushroom Agaricus blazei Murrill in the rat. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20031101 |
Effect of dietary selenite on N-nitrosodiethylamine-induced and phenobarbital promoted multistage hepatocarcinogenesis in rat: reflection in some minerals. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20031101 |
Grape extracts suppress the formation of preneoplastic foci and activity of fatty acid synthase in rat liver. | Experimental & molecular medicine 20031031 |
N-nitrosodiethanolamine urinary excretion in workers exposed to aqueous metalworking fluids. | International archives of occupational and environmental health 20031001 |
Solvent polarity and hydrogen-bonding effects on the nitrogen NMR shieldings of N-nitrosamines and DFT calculations of the shieldings of C-, N-, and O-nitroso systems. | Journal of magnetic resonance (San Diego, Calif. : 1997) 20031001 |
Effects of crude extracts of Agaricus blazei on DNA damage and on rat liver carcinogenesis induced by diethylnitrosamine. | Genetics and molecular research : GMR 20030930 |
Chemopreventive effect of garlic powder diet in diethylnitrosamine-induced rat hepatocarcinogenesis. | Life sciences 20030926 |
Sustained hepatic expression of FoxM1B in transgenic mice has minimal effects on hepatocellular carcinoma development but increases cell proliferation rates in preneoplastic and early neoplastic lesions. | Oncogene 20030918 |
Diversity of selective environmental substrates for human cytochrome P450 2A6: alkoxyethers, nicotine, coumarin, N-nitrosodiethylamine, and N-nitrosobenzylmethylamine. | Toxicology letters 20030915 |
Absence of liver tumor promoting effects of annatto extract (norbixin), a natural carotenoid food color, in a medium-term liver carcinogenesis bioassay using male F344 rats. | Cancer letters 20030910 |
Induction of apoptosis in mouse liver adenoma and carcinoma in vivo by transforming growth factor-beta1. | Journal of cancer research and clinical oncology 20030901 |
Development of a new method for the determination of nitrosamines by micellar electrokinetic capillary chromatography. | Water research 20030901 |
STAT-3 activity in chemically-induced hepatocellular carcinoma. | European journal of cancer (Oxford, England : 1990) 20030901 |
Detection by dual color fluorescence in situ hybridization of in vivo chromosome damage in rat hepatocyte nuclei. | Mutagenesis 20030901 |
Early resistance to cell death and to onset of the mitochondrial permeability transition during hepatocarcinogenesis with 2-acetylaminofluorene. | Proceedings of the National Academy of Sciences of the United States of America 20030819 |
Selective accumulation of ALA-induced PpIX and photodynamic effect in chemically induced hepatocellular carcinoma. | British journal of cancer 20030818 |
Area under the curve as a dose metric for promotional responses following 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure. | Toxicology and applied pharmacology 20030815 |
C57BR/cdJ hepatocarcinogen susceptibility genes act cell-autonomously in C57BR/cdJ<-->C57BL/6J chimeras. | Cancer research 20030815 |
ras oncogene mutations in diethylnitrosamine-induced hepatic tumors in medaka (Oryzias latipes), a teleost fish. | Mutation research 20030805 |
Influence of sodium selenite on glycoprotein contents in normal and N-nitrosodiethylamine initiated and phenobarbital promoted rat liver tumors. | Pharmacological research 20030801 |
Phenobarbital at low dose exerts hormesis in rat hepatocarcinogenesis by reducing oxidative DNA damage, altering cell proliferation, apoptosis and gene expression. | Carcinogenesis 20030801 |
TNP-470 inhibits oxidative stress, nitric oxide production and nuclear factor kappa B activation in a rat model of hepatocellular carcinoma. | Free radical research 20030801 |
Changes in some indices of the synthesis of nitric oxide during the early stages of hepatocarcinogenesis. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20030701 |
Stochastic simulation of hepatic preneoplastic foci development for four chlorobenzene congeners in a medium-term bioassay. | Toxicological sciences : an official journal of the Society of Toxicology 20030601 |
Sodium selenite modulates tumour marker indices in N-nitrosodiethylamine-initiated and phenobarbital-promoted rat liver carcinogenesis. | Cell biochemistry and function 20030601 |
Inhibition of nuclear protein phosphatase activity in mouse hepatocytes by the cyanobacterial toxin microcystin-LR. | Toxicon : official journal of the International Society on Toxinology 20030601 |
Prevention of dual promoting effects of pentachlorophenol, an environmental pollutant, on diethylnitrosamine-induced hepato- and cholangiocarcinogenesis in mice by green tea infusion. | Carcinogenesis 20030601 |
Induction of apoptosis in mouse and human carcinoma cell lines by Emblica officinalis polyphenols and its effect on chemical carcinogenesis. | Journal of experimental & clinical cancer research : CR 20030601 |
Phenotypic reversion of rat neoplastic liver nodules is under genetic control. | International journal of cancer 20030520 |
Effect of arsenic trioxide on rat hepatocellular carcinoma and its renal cytotoxity. | World journal of gastroenterology 20030515 |
Mice lacking a transcriptional corepressor Tob are predisposed to cancer. | Genes & development 20030515 |
Threshold for carcinogenicity of N-nitrosodiethylamine for esophageal tumors in rats. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20030501 |
Molecular profiling of hepatocellular carcinomas developing spontaneously in acyl-CoA oxidase deficient mice: comparison with liver tumors induced in wild-type mice by a peroxisome proliferator and a genotoxic carcinogen. | Carcinogenesis 20030501 |
Spectrum of molecular changes during hepatocarcinogenesis induced by DEN and other chemicals in Fisher 344 male rats [Mechanisms of Ageing and Development 123 (2002) 1665-1680]. | Mechanisms of ageing and development 20030501 |
[Effect of Sorbaria Sorbifolia extract on anti-oxidative activities in rats with precancerosis induced by diethylnitrosamine]. | Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20030501 |
Investigating genotoxic and hematotoxic effects of N-nitrosodimethylamine, N-nitrosodiethylamine and N-nitrosodiethanolamine in the hen's egg-micronucleus test (HET-MN). | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20030401 |
Reduced hepatic tumor incidence in cyclin G1-deficient mice. | Hepatology (Baltimore, Md.) 20030401 |
Inhibition of nitrosodiethylamine-induced hepatocarcinogenesis by dietary turmeric in rats. | Toxicology letters 20030320 |
Insulin-like growth factor binding protein-1 over-expression in transgenic mice inhibits hepatic preneoplasia. | Molecular carcinogenesis 20030301 |
Involvement of YY1 and its correlation with c-myc in NDEA induced hepatocarcinogenesis, its prevention by d-limonene. | Molecular biology reports 20030301 |
Arsenic trioxide induces apoptosis of rat hepatocellular carcinoma cells in vivo. | Journal of experimental & clinical cancer research : CR 20030301 |
Preliminary investigation on regulating effects of different TCM treatments on transcription of the correlated genes of liver cancer in rats. | Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 20030301 |
Suppressive effect of herbal compound 861 on chemical hepatocarcinogenesis in rats. | Chinese medical journal 20030301 |
Chemoprevention of lung carcinogenesis by cacao liquor proanthocyanidins in a male rat multi-organ carcinogenesis model. | Cancer letters 20030227 |
Loss of Igf2 imprinting in monoclonal mouse hepatic tumor cells is not associated with abnormal methylation patterns for the H19, Igf2, and Kvlqt1 differentially methylated regions. | The Journal of biological chemistry 20030221 |
Sodium selenite, dietary micronutrient, prevents the lymphocyte DNA damage induced by N-nitrosodiethylamine and phenobarbital promoted experimental hepatocarcinogenesis. | Journal of cellular biochemistry 20030215 |
Expression of IGF-II in early experimental hepatocellular carcinomas and its significance in early diagnosis. | World journal of gastroenterology 20030215 |
Antigenotoxic, antimutagenic and ROS scavenging activities of a Rhoeo discolor ethanolic crude extract. | Toxicology in vitro : an international journal published in association with BIBRA 20030201 |
Chemoprevention of DMBA-induced UV-B promoted, NOR-1-induced TPA promoted skin carcinogenesis, and DEN-induced phenobarbital promoted liver tumors in mice by extract of beetroot. | Pharmacological research 20030201 |
[Preservation of mucosal specimens before processing in the alkaline single cell microgel electrophoresis assay]. | HNO 20030201 |
Enhancing effects of mustard oil on preneoplastic hepatic foci development in Wistar rats. | Human & experimental toxicology 20030201 |
Agaricus blazei (Himematsutake) does not alter the development of rat diethylnitrosamine-initiated hepatic preneoplastic foci. | Cancer science 20030201 |
Relationship between the imaging features and pathologic alteration in hepatoma of rats. | World journal of gastroenterology 20030115 |
Challenging dogma: thresholds for genotoxic carcinogens? The case of vinyl acetate. | Annual review of pharmacology and toxicology 20030101 |
Suppressive effect of Astragalus membranaceus Bunge on chemical hepatocarcinogenesis in rats. | Cancer chemotherapy and pharmacology 20030101 |
Growth-inhibitory effects of the chemopreventive agent indole-3-carbinol are increased in combination with the polyamine putrescine in the SW480 colon tumour cell line. | BMC cancer 20030101 |
Polychlorinated biphenyls as initiators in liver carcinogenesis: resistant hepatocyte model. | Toxicology and applied pharmacology 20030101 |
Pentachlorophenol (but not phenobarbital) promotes intrahepatic biliary cysts induced by diethylnitrosamine to cholangio cystic neoplasms in B6C3F1 mice possibly due to oxidative stress. | Toxicologic pathology 20030101 |
Prevalidation of a rat liver foci bioassay (RLFB) based on results from 1600 rats: a study report. | Toxicologic pathology 20030101 |
Value of GST-P positive preneoplastic hepatic foci in dose-response studies of hepatocarcinogenesis: evidence for practical thresholds with both genotoxic and nongenotoxic carcinogens. A review of recent work. | Toxicologic pathology 20030101 |
Role of connexin32 and beta-catenin in tumor promotion in mouse liver. | Toxicologic pathology 20030101 |
Different effects of the liver mitogens triiodo-thyronine and ciprofibrate on the development of rat hepatocellular carcinoma. | Toxicologic pathology 20030101 |
Tumor promotion by metanil yellow and malachite green during rat hepatocarcinogenesis is associated with dysregulated expression of cell cycle regulatory proteins. | Teratogenesis, carcinogenesis, and mutagenesis 20030101 |
A medium-term rat liver bioassay for rapid in vivo detection of carcinogenic potential of chemicals. | Cancer science 20030101 |
Suppression of altered hepatic foci development by curcumin in wistar rats. | Nutrition and cancer 20030101 |
Preventive effect of fermented brown rice and rice bran on diethylnitrosoamine and phenobarbital-induced hepatocarcinogenesis in male F344 rats. | Oncology reports 20030101 |
Stabilization of membrane bound enzyme profiles by sodium selenite in N-nitrosodiethylamine induced and phenobarbital promoted hepatocarcinogenesis in rats. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20030101 |
S-allylcysteine inhibits circulatory lipid peroxidation and promotes antioxidants in N-nitrosodiethylamine-induced carcinogenesis. | Polish journal of pharmacology 20030101 |
The copper-chelating agent, trientine, attenuates liver enzyme-altered preneoplastic lesions in rats by angiogenesis suppression. | Oncology reports 20030101 |
[Liver radiosensitivity to gamma radiation in mice poisoned with N-nitrosodiethylamine]. | Roczniki Panstwowego Zakladu Higieny 20030101 |
Effects of dietary taurine supplementation on hepatic morphological changes of rats in diethylnitrosamine-induced hepatocarcinogenesis. | Advances in experimental medicine and biology 20030101 |
[Tumor-associated hetero-organic antigens as markers of deranged cell differentiation and malignancy]. | Voprosy onkologii 20030101 |
[N-nitrosodiethylamine-induced changes in the liver of syrian hamster with superinvasive opistorchiasis]. | Voprosy onkologii 20030101 |
Diethylnitrosamine may induce esophageal dysplasia after local intramural administration. | Roczniki Akademii Medycznej w Bialymstoku (1995) 20030101 |
Peroxisomal enzymes and 8-hydroxydeoxyguanosine in rat liver treated with perfluorooctanoic acid. | Disease markers 20030101 |
Chemopreventive effects of melatonin on diethylnitrosamine and phenobarbital-induced hepatocarcinogenesis in male F344 rats. | Nutrition and cancer 20030101 |
Biological consequences of overexpressing or eliminating N-acetylglucosaminyltransferase-TIII in the mouse. | Biochimica et biophysica acta 20021219 |
K vitamins, PTP antagonism, and cell growth arrest. | Journal of cellular physiology 20021201 |
Dietary influence of selenium on the incidence of N-nitrosodiethylamine-induced hepatoma with reference to drug and glutathione metabolizing enzymes. | Cell biochemistry and function 20021201 |
Cellular origin of hepatocellular carcinomas. | Seminars in cell & developmental biology 20021201 |
[Superparamagnetic iron oxide-enhanced magnetic resonance imaging of hepatocellular carcinoma in rats]. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20021201 |
Effects of tea on preneoplastic lesions and cell cycle regulators in rat liver. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20021201 |
Intake of volatile N-nitrosamines and their ability to exogenously synthesize in the diet of inhabitants from high-risk area of esophageal cancer in southern China. | Biomedical and environmental sciences : BES 20021201 |
Anticarcinogenic effect and modification of cytochrome P450 2E1 by dietary garlic powder in diethylnitrosamine-initiated rat hepatocarcinogenesis. | Journal of biochemistry and molecular biology 20021130 |
Dietary exposure and urinary excretion of total N-nitroso compounds, nitrosamino acids and volatile nitrosamine in inhabitants of high- and low-risk areas for esophageal cancer in southern China. | International journal of cancer 20021120 |
High vascular endothelial growth factor (VEGF) expression in chemically-induced hepatic microcancers in mice. | Journal of hepatology 20021101 |
Influence of aqueous extract of Agaricus blazei on rat liver toxicity induced by different doses of diethylnitrosamine. | Journal of ethnopharmacology 20021101 |
Influences of a dietary fatty acid composition on the emergence of glutathione S-transferase-P (GST-P) positive foci in the liver of carcinogen-treated rats. | Prostaglandins, leukotrienes, and essential fatty acids 20021101 |
Spectrum of molecular changes during hepatocarcinogenesis induced by DEN and other chemicals in Fischer 344 male rats. | Mechanisms of ageing and development 20021101 |
Changes in hepatic enzyme activities in transgenic mice carrying human prototype c-Ha-ras gene treated with diethylnitrosamine. | The Journal of veterinary medical science 20021101 |
N-ethyl-N-hydroxyethylnitrosamine (EHEN)-induced renal and hepatocarcinogenesis in the tumor suppressor Tsc2 transgenic rat. | Cancer letters 20021028 |
Overexpression of glutamine synthetase is associated with beta-catenin-mutations in mouse liver tumors during promotion of hepatocarcinogenesis by phenobarbital. | Cancer research 20021015 |
In ovo carcinogenicity assay (IOCA): evaluation of mannitol, caprolactam and nitrosoproline. | Archives of toxicology 20021001 |
Dynamic changes of matrix metalloproteinases in rat liver during the development of diethylnitrosamine-induced hepatocarcinoma. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20021001 |
Lack of a dose-response relationship for carcinogenicity in the rat liver with low doses of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline or N-nitrosodiethylamine. | Japanese journal of cancer research : Gann 20021001 |
Suppression of lung metastasis by aspirin but not indomethacin in an in vivo model of chemically induced hepatocellular carcinoma. | Japanese journal of cancer research : Gann 20021001 |
Decomposition of N-nitrosamines, and concomitant release of nitric oxide by Fenton reagent under physiological conditions. | Mutation research 20020926 |
Inhibitory effects of lemon grass (Cymbopogon citratus, Stapf) extract on the early phase of hepatocarcinogenesis after initiation with diethylnitrosamine in male Fischer 344 rats. | Cancer letters 20020908 |
1alpha,25-Dihydroxyvitamin D(3) inhibits rat liver ultrastructural changes and the development of gamma-glutamyltranspeptidase-positive foci in diethylnitrosamine-initiated and streptozotocin-induced diabetes-promoted hepatocarcinogenesis. | Cell biochemistry and function 20020901 |
Demonstration of direct lineage between hepatocytes and hepatocellular carcinoma in diethylnitrosamine-treated rats. | Hepatology (Baltimore, Md.) 20020901 |
Follistatin overexpression in rodent liver tumors: a possible mechanism to overcome activin growth control. | Molecular carcinogenesis 20020901 |
Brain stem GABA receptor functional regulation during rat liver cell proliferation. | Neurochemical research 20020901 |
Impact of hypercholesterolemia on in vitro toxicity of N-nitrosodiethylamine: effect on lipidperoxidation of blood and tissue. | Indian journal of experimental biology 20020901 |
Promotion of altered hepatic foci by 2,3,7,8-tetrachlorodibenzo-p-dioxin and 17beta-estradiol in male Sprague-Dawley rats. | Toxicological sciences : an official journal of the Society of Toxicology 20020801 |
Cytotoxicity of fumonisin B1, diethylnitrosamine, and catechol on the SNO esophageal cancer cell line. | Environmental health perspectives 20020801 |
Chromosome mapping of multiple loci affecting the genetic predisposition to rat liver carcinogenesis. | Cancer research 20020801 |
Role of human cytochrome P450 (CYP) in the metabolic activation of nitrosamine derivatives: application of genetically engineered Salmonella expressing human CYP. | Drug metabolism reviews 20020801 |
[Influence of spleen on cell cycle and expression of proliferating cell nuclear antigen of the liver during diethylnitrosamine-induced rat hepatocarcinogenesis]. | Zhonghua wai ke za zhi [Chinese journal of surgery] 20020801 |
A glycomic approach to hepatic tumors in N-acetylglucosaminyltransferase III (GnT-III) transgenic mice induced by diethylnitrosamine (DEN): identification of haptoglobin as a target molecule of GnT-III. | Free radical research 20020801 |
Promoting effects of monomethylarsonic acid, dimethylarsinic acid and trimethylarsine oxide on induction of rat liver preneoplastic glutathione S-transferase placental form positive foci: a possible reactive oxygen species mechanism. | International journal of cancer 20020710 |
Inhibition of renin-angiotensin system attenuates liver enzyme-altered preneoplastic lesions and fibrosis development in rats. | Journal of hepatology 20020701 |
Marked inhibition of testosterone biosynthesis by the hepatotoxin nodularin due to apoptosis of Leydig cells. | Molecular carcinogenesis 20020701 |
Anomalous elevation of glutathione S-transferase P-form (GST-P) in the elementary process of epigenetic initiation of chemical hepatocarcinogenesis in rats. | Carcinogenesis 20020701 |
Chemoprevention of hepatocarcinogenesis: S-adenosyl-L-methionine. | Alcohol (Fayetteville, N.Y.) 20020701 |
[The expression of bcl-2 and bax genes during microcystin induced liver tumorigenesis]. | Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20020701 |
Genotoxic and anti-genotoxic properties of Calendula officinalis extracts in rat liver cell cultures treated with diethylnitrosamine. | Toxicology in vitro : an international journal published in association with BIBRA 20020601 |
Cell cycle deregulation in liver lesions of rats with and without genetic predisposition to hepatocarcinogenesis. | Hepatology (Baltimore, Md.) 20020601 |
Down-regulation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)-induced CYP1A2 expression is associated with bovine lactoferrin inhibition of MeIQx-induced liver and colon carcinogenesis in rats. | Japanese journal of cancer research : Gann 20020601 |
Molecular profiling of genes up-regulated during promotion by phenobarbital treatment in a medium-term rat liver bioassay. | Carcinogenesis 20020601 |
Enhanced GABA(B) receptor in neoplastic rat liver: induction of DNA synthesis by baclofen in hepatocyte cultures. | Journal of biochemistry, molecular biology, and biophysics : JBMBB : the official journal of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) 20020601 |
Caffeine, quercetin and alizarin stimulate the exhalation of metabolic products of [14C]-N-nitrosodiethylamine in mice. | Indian journal of experimental biology 20020601 |
Down-regulation of von Hippel-Lindau protein in N-nitroso compound-induced rat non-clear cell renal tumors. | Cancer letters 20020508 |
Distinctive gene expression of receptor-type tyrosine kinase families during rat hepatocarcinogenesis. | International journal of molecular medicine 20020501 |
Effect of ethanol treatment on metabolic activation and detoxification of esophagus carcinogenic N-nitrosamines in rat liver. | Mutagenesis 20020501 |
Hypoxia-induced VEGF and collagen I expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosis. | Hepatology (Baltimore, Md.) 20020501 |
Effects of Sho-Saiko-to on hepatocarcinogenesis and 8-hydroxy-2'-deoxyguanosine formation. | Hepatology (Baltimore, Md.) 20020501 |
Bcl-2 expression inhibits liver carcinogenesis and delays the development of proliferating foci. | The American journal of pathology 20020501 |
Morphology and morphometric investigation of hepatocellular preneoplastic lesions and neoplasms in connexin32-deficient mice. | Carcinogenesis 20020501 |
Reduction of hepatocarcinogenesis by ursodeoxycholic acid in rats. | Carcinogenesis 20020501 |
[Basic research on lung cancer]. | Nihon rinsho. Japanese journal of clinical medicine 20020501 |
Alterations of the Fhit gene in hepatocellular carcinomas induced by N-nitrosodiethylamine in rats. | Molecular carcinogenesis 20020501 |
The in vivo apoptotic effect of interferon alfa-2b on rat preneoplastic liver involves Bax protein. | Hepatology (Baltimore, Md.) 20020401 |
Effects of N-acetylcysteine in an esophageal carcinogenesis model in rats treated with diethylnitrosamine and diethyldithiocarbamate. | International journal of cancer 20020401 |
Microsome-mediated oxidation of N-nitrosodiethanolamine (NDELA), a bident carcinogen. | Chemical research in toxicology 20020401 |
DNA adducts from N-nitrosodiethanolamine and related beta-oxidized nitrosamines in vivo: (32)P-postlabeling methods for glyoxal- and O(6)-hydroxyethyldeoxyguanosine adducts. | Chemical research in toxicology 20020401 |
CYP2A6/2A7 and CYP2E1 expression in human oesophageal mucosa: regional and inter-individual variation in expression and relevance to nitrosamine metabolism. | Carcinogenesis 20020401 |
Role of mouse spleen cell HMG proteins and their poly-ADP-ribosylation in betelnut induced carcinogenesis. | Indian journal of biochemistry & biophysics 20020401 |
Further phenotypic characterization of pso mutants of Saccharomyces cerevisiae with respect to DNA repair and response to oxidative stress. | Genetics and molecular research : GMR 20020331 |
Regulation of cell proliferation, apoptosis, and transcription factor activities during the promotion of liver carcinogenesis by polychlorinated biphenyls. | Toxicology and applied pharmacology 20020315 |
Hepatocyte growth factor promotes hepatocarcinogenesis through c-Met autocrine activation and enhanced angiogenesis in transgenic mice treated with diethylnitrosamine. | Oncogene 20020314 |
Nonadditive hepatic tumor promoting effects by a mixture of two structurally different polychlorinated biphenyls in female rat livers. | Toxicological sciences : an official journal of the Society of Toxicology 20020301 |
Nrf2 transactivator-independent GSTP1-1 expression in 'GSTP1-1 positive' single cells inducible in female mouse liver by DEN: a preneoplastic character of possible initiated cells. | Carcinogenesis 20020301 |
[Dynamic study on expression of gelatinase A and its natural inhibitor during invasion and metastasis of induced lung cancer in Wistar rats]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20020301 |
Chemopreventive effect of orange oil on the development of hepatic preneoplastic lesions induced by N-nitrosodiethylamine in rats: an ultrastructural study. | Indian journal of experimental biology 20020301 |
Anticarcinogenic effect of black tea on pulmonary tumors in Swiss albino mice. | Cancer letters 20020225 |
Summation of initiation activities in the liver after partial hepatectomy. | Cancer letters 20020208 |
Fast microwave-assisted dansylation of N-nitrosamines. Analysis by high-performance liquid chromatography with fluorescence detection. | Journal of chromatography. A 20020208 |
Expression of P-glycoprotein in rat hepatocarcinogenesis by diethylnitrosamine and the modulation by anticancer drugs. | Hepatology research : the official journal of the Japan Society of Hepatology 20020201 |
Hepatocyte growth factor and c-Met inhibition by hepatic cell hypoxia: a potential mechanism for liver regeneration failure in experimental cirrhosis. | The American journal of pathology 20020201 |
Diethylnitrosamine induces long-lasting re-expression of insulin-like growth factor II during early stages of liver carcinogenesis in mice. | Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20020201 |
Effects of fasting and intermittent fasting on rat hepatocarcinogenesis induced by diethylnitrosamine. | Teratogenesis, carcinogenesis, and mutagenesis 20020101 |
Quantitation of the cancer process in C57BL/6J, B6C3F1 and C3H/HeJ mice. | Toxicologic pathology 20020101 |
Systemic administration of liposome-encapsulated OK-432 prolongs the survival of rats with hepatocellular carcinoma through the induction of IFN-gamma-producing hepatic lymphocytes. | Journal of gastroenterology and hepatology 20020101 |
Probucol and liver efficiency during chemically-induced hepatocarcinogenesis. | Anticancer research 20020101 |
Lack of modification of rat hepatocarcinogenesis by fernane-type triterpenoids, isolated from a Euphorbia genus. | Teratogenesis, carcinogenesis, and mutagenesis 20020101 |
Overexpression of cyclin D1 is associated with the decondensation of chromatin during den-induced sequential hepatocarcinogenesis. | Cell biology international 20020101 |
[Content of N-nitrosamines in smoked fish and canned food]. | Gigiena i sanitariia 20020101 |
Administration of diethylnitrosamine in the immediate postnatal period coupled with exposure to a choline deficient diet accelerates hepatocarcinogenesis in the rat. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20020101 |
Experimental esophageal carcinogenesis: technical standardization and results. | Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20020101 |
[Changes in some parameters of nitric oxide synthesis in the early periods of development of hepatocarcinogenesis]. | Likars'ka sprava 20020101 |
[Studies on extracellular matrices in rat hepatocarcinogenesis induced by diethylnitrosamine]. | Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao 20020101 |
[Radioprotective and antineoplastic activity of polyene antibiotics combined with dimethyl sulfoxide]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20020101 |
Effect of A-L tonic capsule on DNA content in rat experimental hepatocarcinogenesis. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20020101 |
In vivo changes in the intestinal lipid peroxidation and the crypt response to whole-body gamma irradiation in diethylnitrosamine-treated mice. | Roczniki Panstwowego Zakladu Higieny 20020101 |
Menhaden oil inhibited gamma-glutamyltransferase-positive altered hepatic foci in female Sprague-Dawley rats. | Nutrition and cancer 20020101 |
N-Nitrosodiethanolamine. | Report on carcinogens : carcinogen profiles 20020101 |
N-Nitrosodiethylamine. | Report on carcinogens : carcinogen profiles 20020101 |
Detection of DNA adducts using a quantitative long PCR technique and the fluorogenic 5' nuclease assay (TaqMan). | Mutation research 20011212 |
Cytochrome b(5) coexpression increases the CYP2E1-dependent mutagenicity of dialkylnitrosamines in methyltransferase-deficient strains of Salmonella typhimurium. | Mutation research 20011212 |
Chemopreventive efficacy of selenium against N-nitrosodiethylamine-induced hepatoma in albino rats. | Cell biochemistry and function 20011201 |
Anticarcinogenic effect of red ginseng on the development of liver cancer induced by diethylnitrosamine in rats. | Journal of Korean medical science 20011201 |
Decreased expression of Bcl-x protein during hepatocarcinogenesis induced exogenously and endogenously in rats. | Japanese journal of cancer research : Gann 20011201 |
Reduced ATM kinase activity and an attenuated p53 response to DNA damage in carcinogen-induced preneoplastic hepatic lesions in the rat. | Carcinogenesis 20011201 |
Release of nitric oxide together with carbon-centered radicals from N-nitrosamines by ultraviolet light irradiation. | Free radical research 20011201 |
[Studies on liver cancer induced by non-necrotizing dose of diethylnitrosamine in rats]. | Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao 20011201 |
Selective pressure during tumor promotion by phenobarbital leads to clonal outgrowth of beta-catenin-mutated mouse liver tumors. | Oncogene 20011122 |
Role of human cytochrome P450 (CYP) in the metabolic activation of N-alkylnitrosamines: application of genetically engineered Salmonella typhimurium YG7108 expressing each form of CYP together with human NADPH-cytochrome P450 reductase. | Mutation research 20011101 |
The importance of distinct metabolites of N-nitrosodiethylamine for its in vivo mutagenic specificity. | Mutation research 20011101 |
The little mutation suppresses DEN-induced hepatocarcinogenesis in mice and abrogates genetic and hormonal modulation of susceptibility. | Carcinogenesis 20011101 |
Rat oesophageal cytochrome P450 (CYP) monooxygenase system: comparison to the liver and relevance in N-nitrosodiethylamine carcinogenesis. | Carcinogenesis 20011101 |
Organotropic chemopreventive effects of n-3 unsaturated fatty acids in a rat multi-organ carcinogenesis model. | Japanese journal of cancer research : Gann 20011101 |
The polycyclic musk 7-acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphthaline lacks liver tumor initiating and promoting activity in rats exposed to human-relevant doses. | Archives of toxicology 20011101 |
Inheritance of resistance to promotion of preneoplastic liver lesions in Copenhagen rats. | Experimental biology and medicine (Maywood, N.J.) 20011001 |
Butylhydroxytoluene (BHT) increases susceptibility of transgenic rasH2 mice to lung carcinogenesis. | Journal of cancer research and clinical oncology 20011001 |
Cell type-specific induction of O6-alkylguanine-DNA alkyltransferase mRNA expression in rat liver during regeneration, inflammation and preneoplasia. | Journal of cancer research and clinical oncology 20011001 |
Efficient and cancer-selective gene transfer to hepatocellular carcinoma in a rat using adenovirus vector with iodized oil esters. | Cancer gene therapy 20011001 |
Immunohistochemical characterization of hepatoblastomas in B6C3F1 mice treated with diethylnitrosamine and sodium phenobarbital. | The Journal of veterinary medical science 20011001 |
[Genetic control of hepatocarcinogenesis in mice]. | Nihon rinsho. Japanese journal of clinical medicine 20011001 |
Assessment of chronic toxicity and carcinogenicity in an accelerated cancer bioassay in rats of moxifloxacin, a quinolone antibiotic. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20011001 |
Strain variation in renal carcinogenesis by N-ethyl-N-hydroxyethylnitrosamine in F1 (Wistar-Fischer) rats. | Cancer letters 20010920 |
Heterozygous mice for the transforming growth factor-beta type II receptor gene have increased susceptibility to hepatocellular carcinogenesis. | Cancer research 20010915 |
Matrix metalloproteinases-2 and 9 do not play a role in the growth of preneoplastic liver lesions in F344 rats. | Experimental biology and medicine (Maywood, N.J.) 20010901 |
Resistance of primary cultured mouse hepatic tumor cells to cellular senescence despite expression of p16(Ink4a), p19(Arf), p53, and p21(Waf1/Cip1). | Molecular carcinogenesis 20010901 |
Diethylnitrosamine causes pituitary damage, disturbs hormone levels, and reduces sexual dimorphism of certain liver functions in the rat. | Environmental health perspectives 20010901 |
Effect of alpha-tocopherol on hepatocarcinogenesis in transforming growth factor-alpha (TGF-alpha) transgenic mice treated with diethylnitrosamine. | International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20010901 |
Effect of metanil yellow and malachite green on DNA synthesis in N-nitrosodiethylamine induced preneoplastic rat livers. | Indian journal of experimental biology 20010901 |
Hepatocellular expression of a dominant-negative mutant TGF-beta type II receptor accelerates chemically induced hepatocarcinogenesis. | Oncogene 20010816 |
Clustering of hepatotoxins based on mechanism of toxicity using gene expression profiles. | Toxicology and applied pharmacology 20010815 |
Low gastric toxicity of nitric oxide-releasing aspirin, NCX-4016, in rats with cirrhosis and arthritis. | Digestive diseases and sciences 20010801 |
Role of Atp7b gene in spontaneous and N-diethylnitrosamine-induced carcinogenesis in a new congenic strain, WKAH.C-Atp7b rats. | Japanese journal of cancer research : Gann 20010801 |
Reaction of fumonisin with glucose prevents promotion of hepatocarcinogenesis in female F344/N rats while maintaining normal hepatic sphinganine/sphingosine ratios. | Journal of agricultural and food chemistry 20010801 |
Proteome analysis of rat hepatomas: carcinogen-dependent tumor-associated protein variants. | Electrophoresis 20010801 |
Preventive effect of FK143, a 5alpha-reductase inhibitor, on chemical hepatocarcinogenesis in rats. | Clinical cancer research : an official journal of the American Association for Cancer Research 20010701 |
Induction of hepatic 8-oxo-deoxyguanosine adducts by 2,3,7,8-tetrachlorodibenzo-p-dioxin in Sprague-Dawley rats is female-specific and estrogen-dependent. | Chemical research in toxicology 20010701 |
Cancare-a herbal formulation inhibits chemically induced tumours in experimental animals. | Indian journal of experimental biology 20010701 |
Importance of DNA repair in carcinogenesis: evidence from transgenic and gene targeting studies. | Mutation research 20010602 |
Involvement of gap junctions in tumor suppression: analysis of genetically-manipulated mice. | Mutation research 20010602 |
Chemopreventive effects of scordinin on diethylnitrosamine and phenobarbital-induced hepatocarcinogenesis in male F344 rats. | Japanese journal of cancer research : Gann 20010601 |
Regulation of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced tumor promotion by 17 beta-estradiol in female Sprague--Dawley rats. | Toxicology and applied pharmacology 20010515 |
Expression profiling and identification of novel genes in hepatocellular carcinomas. | Oncogene 20010510 |
DNA damage induced by red food dyes orally administered to pregnant and male mice. | Toxicological sciences : an official journal of the Society of Toxicology 20010501 |
Inhibition of chemical carcinogenesis by berberine in rats and mice. | The Journal of pharmacy and pharmacology 20010501 |
Mutagen sensitivity of nasopharyngeal cancer patients. | Mutation research 20010405 |
Overexpressed growth hormone (GH) synergistically promotes carcinogen-initiated liver tumour growth by promoting cellular proliferation in emerging hepatocellular neoplasms in female and male GH-transgenic mice. | Liver 20010401 |
Genotoxic effects of N-nitrosodicyclohexylamine in isolated human lymphocytes. | Archives of toxicology 20010401 |
Study on mechanism of multistep hepatotumorigenesis in rat: development of hepatotumorigenesis. | Journal of veterinary science 20010401 |
Microarray analysis of hepatotoxins in vitro reveals a correlation between gene expression profiles and mechanisms of toxicity. | Toxicology letters 20010331 |
1 alpha,25-Dihydroxyvitamin D(3) inhibits rat liver ultrastructural changes in diethylnitrosamine-initiated and phenobarbital promoted rat hepatocarcinogenesis. | Journal of cellular biochemistry 20010326 |
Frequency of CYP2A6 gene deletion and its relation to risk of lung and esophageal cancer in the Chinese population. | International journal of cancer 20010320 |
Establishment of rat hepatocellular carcinoma cell lines with differing metastatic potential in nude mice. | International journal of cancer 20010315 |
Gas chromatographic-mass spectrometric determination of hydrophilic compounds in environmental water by solid-phase extraction with activated carbon fiber felt. | Journal of chromatography. A 20010309 |
Effect of selenium on N-nitrosodiethylamine-induced multistage hepatocarcinogenesis with reference to lipid peroxidation and enzymic antioxidants. | Cell biochemistry and function 20010301 |
Sex hormone dependency of diethylnitrosamine-induced liver tumors in mice and chemoprevention by leuprorelin. | Japanese journal of cancer research : Gann 20010301 |
A clonal growth model: time-course simulations of liver foci growth following penta- or hexachlorobenzene treatment in a medium-term bioassay. | Cancer research 20010301 |
Activation of beta-catenin during hepatocarcinogenesis in transgenic mouse models: relationship to phenotype and tumor grade. | Cancer research 20010301 |
Sequential changes in hepatocarcinogenesis induced by diethylnitrosamine plus thioacetamide in Fischer 344 rats: induction of gankyrin expression in liver fibrosis, pRB degradation in cirrhosis, and methylation of p16(INK4A) exon 1 in hepatocellular carcinoma. | Molecular carcinogenesis 20010301 |
Chemically induced carcinogenesis: a comparison of 1-methyl-1-nitrosourea, 7,12-dimethylbenzanthracene,diethylnitroso-amine and azoxymethan models (minireview). | Endocrine regulations 20010301 |
Bioassay of mannitol and caprolactam and assessment of response to diethylnitrosamine in heterozygous p53-deficient (+/-) and wild type (+/+) mice. | Archives of toxicology 20010301 |
Liposome encapsulated tumor-associated antigens elicited humoral and cellular immune responses in mice bearing tumor. | Indian journal of experimental biology 20010301 |
Presence of a no-observed effect level for enhancing effects of development of the alpha-isomer of benzene hexachloride (alpha-BHC) on diethylnitrosamine-initiated hepatic foci in rats. | Cancer letters 20010226 |
Establishment and characterization of three new rat renal cell carcinoma cell lines from N-ethyl-N-hydroxyethylnitrosamine-induced basophilic cell tumors. | Pathology international 20010201 |
Long-term dehydroepiandrosterone and 16alpha-fluoro-5-androsten-17-one administration enhances DNA synthesis and induces expression of c-fos and c-Ha-ras in a selected population of preneoplastic lesions in liver of diethylnitrosamine-initiated rats. | Carcinogenesis 20010201 |
Resistance of Copenhagen rats to hepatocarcinogenesis does not involve T-cell immunity. | Carcinogenesis 20010201 |
Epoprostenol sodium, a prostaglandin I2, lacks tumor promoting effects in a medium-term liver carcinogenesis bioassay in rats. | Cancer letters 20010126 |
Mdr1b facilitates p53-mediated cell death and p53 is required for Mdr1b upregulation in vivo. | Oncogene 20010118 |
Gene therapy of orthotopic hepatocellular carcinoma in rats using adenovirus coding for interleukin 12. | Hepatology (Baltimore, Md.) 20010101 |
Selective left-lobe atrophy by nodularin treatment accompanied by reduced protein phosphatase 1/2A and increased peroxisome proliferation in rat liver. | International journal of cancer 20010101 |
Alterations of the transforming growth factor-beta signaling pathway in hepatocellular carcinomas induced endogenously and exogenously in rats. | Japanese journal of cancer research : Gann 20010101 |
Hypothalamic GABA receptor functional regulation and liver cell proliferation. | Molecular and cellular biochemistry 20010101 |
Anti-tumor promoting activity of Asteracantha longifolia against experimental hepatocarcinogenesis in rats. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20010101 |
[DNA repair if mucous membrane cells and lymphocytes with the comet assay]. | Laryngo- rhino- otologie 20010101 |
Tumor-specific action of sodium 5,6-benzylidene-L-ascorbate in N-nitrosodiethylamine-administered mouse model. | Anticancer research 20010101 |
Possible prevention by abieslactone of development of diethylnitrosamine-initiated GST-P positive foci in the rat liver. | Teratogenesis, carcinogenesis, and mutagenesis 20010101 |
1alpha, 25-Dihydroxyvitamin D3 suppresses the effect of streptozotocin-induced diabetes during chemical rat liver carcinogenesis. | Cell biology international 20010101 |
Enhancement of N-nitrosodiethylamine-initiated hepatocarcinogenesis by phentoin in male F344/NCr rats at a dose causing maximal induction of CYP2B. | International journal of toxicology 20010101 |
Genotoxicity of nitroso compounds and sodium dichromate in a model combining organ cultures of human nasal epithelia and the comet assay. | ORL; journal for oto-rhino-laryngology and its related specialties 20010101 |
Specific genomic alterations in rat renal cell carcinomas induced by N-ethyl-N-hydroxyethylnitrosamine. | Toxicologic pathology 20010101 |
An in vivo method for using 5-bromo-2'-deoxyuridine (BrdU) as a marker of chemically-induced hepatocellular proliferation in the Japanese medaka (Oryzias latipes). | Toxicologic pathology 20010101 |
Nuclear Ras: unexpected subcellular distribution of oncogenic forms. | Journal of cellular biochemistry. Supplement 20010101 |
Nitric oxide synthase inhibitors reduced lipid peroxidation in N-nitrosodiethylamine-treated rats. | Roczniki Panstwowego Zakladu Higieny 20010101 |
Greater expression of transforming growth factor alpha and proliferating cell nuclear antigen staining in mouse hepatoblastomas than hepatocellular carcinomas induced by a diethylnitrosamine-sodium phenobarbital regimen. | Toxicologic pathology 20010101 |
Determination of N-nitrosodimethylamine in environmental aqueous samples by isotope-dilution GC/MS-SIM. | Journal of AOAC International 20010101 |
Effects of griseofulvin in medium-term liver carcinogenesis assay and peripheral blood micronucleus test in rat. | Teratogenesis, carcinogenesis, and mutagenesis 20010101 |
Vitamin A and all-trans and 9-cis retinoic acids inhibit cell proliferation during the progression phase of hepatocarcinogenesis in Wistar rats. | Nutrition and cancer 20010101 |
Predicting the mutagenicity of tobacco-related N-nitrosamines in humans using 11 strains of Salmonella typhimurium YG7108, each coexpressing a form of human cytochrome P450 along with NADPH-cytochrome P450 reductase. | Environmental and molecular mutagenesis 20010101 |
Evaluation of genotoxic activity of maleic hydrazide, ethyl methane sulfonate, and N-nitroso diethylamine in Tradescantia. | Salud publica de Mexico 20010101 |
Dose-dependent promotion by phenylethyl isothiocyanate, a known chemopreventer, of two-stage rat urinary bladder and liver carcinogenesis. | Nutrition and cancer 20010101 |
Comparison between the Effect of Soybean and Goat's Milk on Tumor-Marker Enzyme Activities During Hepatocarcinogenesis in Rats. | The Malaysian journal of medical sciences : MJMS 20010101 |
Liver tumor-promoting activity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in TCDD-sensitive and TCDD-resistant rat strains. | Cancer research 20001215 |
Mutagenicity of nitrosamines in methyltransferase-deficient strains of Salmonella typhimurium coexpressing human cytochrome P450 2E1 and reductase. | Mutation research 20001106 |
Loss of nuclear p53 protein in preneoplastic rat hepatocytes is accompanied by Mdm2 and Bcl-2 overexpression and by defective response to DNA damage in vivo. | Hepatology (Baltimore, Md.) 20001001 |
Ovarian tumors in rats induced by chronic 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment. | Cancer research 20001001 |
Lack of phenobarbital-mediated promotion of hepatocarcinogenesis in connexin32-null mice. | Cancer research 20000915 |
Overexpression of G1/S cyclins and PCNA and their relationship to tyrosine phosphorylation and dephosphorylation during tumor promotion by metanil yellow and malachite green. | Toxicology letters 20000727 |
[Effect of tea polyphenols and tea pigments on inducing the activity of phase II detoxicating enzymes and on the chemoprevention of liver precancerous lesions]. | Wei sheng yan jiu = Journal of hygiene research 20000530 |
Absence of p16, p21 and p53 gene alterations in hepatocellular carcinomas induced by N-nitrosodiethylamine or a choline-deficient L-amino acid-defined diet in rats. | Cancer letters 20000428 |
Evaluation of flutamide genotoxicity in rats and in primary human hepatocytes. | Pharmacology & toxicology 20000301 |
Bile acid secretion during rat liver carcinogenesis. | Life sciences 20000211 |
Comparative hepatocarcinogenicity of hexachlorobenzene, pentachlorobenzene, 1,2,4,5-tetrachlorobenzene, and 1,4-dichlorobenzene: application of a medium-term liver focus bioassay and molecular and cellular indices. | Toxicological sciences : an official journal of the Society of Toxicology 20000201 |
Diet restriction increases ubiquinone contents and inhibits progression of hepatocellular carcinoma in the rat. | Scandinavian journal of gastroenterology 20000101 |
Lack of p53 protein expression in preneoplastic rat hepatocytes in vitro after exposure to N-acetoxy-acetylaminofluorene, X-rays or a proteasome inhibitor. | European journal of cancer (Oxford, England : 1990) 20000101 |
Further evidence for chemopreventive potential of beta-carotene against experimental carcinogenesis: diethylnitrosamine-initiated and phenobarbital-promoted hepatocarcinogenesis is prevented more effectively by beta-carotene than by retinoic acid. | Nutrition and cancer 20000101 |
Induction of lung lesions in female rats following chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. | Toxicologic pathology 20000101 |
The relationship between decrease in Cx32 and induction of P450 isozymes in the early phase of clofibrate hepatocarcinogenesis in the rat. | Archives of toxicology 19990901 |
Different frequencies and patterns of beta-catenin mutations in hepatocellular carcinomas induced by N-nitrosodiethylamine and a choline-deficient L-amino acid-defined diet in rats. | Cancer research 19990815 |
Dose-dependent induction of carcinomas and glutathione S-transferase placental form negative eosinophilic foci in the rat liver by di(2-ethylhexyl)phthalate after diethylnitrosamine initiation. | The Journal of toxicological sciences 19990801 |
Promoting activity of the herbicide dicamba (2-methoxy-3, 6-dichlorobenzoic acid) in two stage hepatocarcinogenesis. | International journal of oncology 19990101 |
Natural killer activity in a medium-term multi-organ bioassay for carcinogenesis. | Japanese journal of cancer research : Gann 19990101 |
d-limonene chemoprevention of hepatocarcinogenesis in AKR mice: inhibition of c-jun and c-myc. | Oncology reports 19990101 |
Inhibitory effect of Trianthema portulacastrum L. diethylnitroso-amine-induced phenobarbital promoted hepatocarcinogenesis. | Neoplasma 19990101 |
Presence of a threshold for promoting effects of phenobarbital on diethylnitrosamine-induced hepatic foci in the rat. | Carcinogenesis 19980801 |
Ferric nitrilotriacetate promotes N-diethylnitrosamine-induced renal tumorigenesis in the rat: implications for the involvement of oxidative stress. | Carcinogenesis 19980601 |
Studies of initiation and promotion of carcinogenesis by N-nitroso compounds. | Cancer letters 19980130 |
Effects of the lignan, arctiin, on 17-beta ethinyl estradiol promotion of preneoplastic liver cell foci development in rats. | Anticancer research 19980101 |
Tea and tea polyphenols inhibit cell hyperproliferation, lung tumorigenesis, and tumor progression. | Experimental lung research 19980101 |
The tetratricopeptide repeat containing Tg737 gene is a liver neoplasia tumor suppressor gene. | Oncogene 19971009 |
p53 protein expression by hepatocarcinogens in the rat liver and its potential role in mitoinhibition of normal hepatocytes as a mechanism of hepatic tumour promotion. | Carcinogenesis 19970501 |
Enhancing effects of phenobarbital and 3-methylcholanthrene on GST-P-positive liver cell foci development in a new medium-term rat liver bioassay using D-galactosamine. | Journal of toxicology and environmental health 19970411 |
Effects of n-tritriacontane-16,18-dione, curcumin, chlorphyllin, dihydroguaiaretic acid, tannic acid and phytic acid on the initiation stage in a rat multi-organ carcinogenesis model. | Cancer letters 19970226 |
Highly metastatic hepatocellular carcinomas induced in male F344 rats treated with N-nitrosomorpholine in combination with other hepatocarcinogens show a high incidence of p53 gene mutations along with altered mRNA expression of tumor-related genes. | Cancer letters 19970115 |
Quantitative relationship between transforming growth factor-alpha and hepatic focal phenotype and progression in female mouse liver. | Toxicologic pathology 19970101 |
Induction of hsp 70 in HepG2 cells in response to hepatotoxicants. | Toxicology and applied pharmacology 19961101 |
Decreased connexin32 and a characteristic enzyme phenotype in clofibrate-induced preneoplastic lesions not shared with spontaneously occurring lesions in the rat liver. | Carcinogenesis 19961101 |
Role of the pituitary in tumor promotion with ethinyl estradiol in rat liver. | Hepatology (Baltimore, Md.) 19961001 |
Cell proliferation and regulation of negative growth factors in mouse liver foci. | Carcinogenesis 19960901 |
Enhancement of N-nitrosodiethylamine-initiated hepatocarcinogenesis caused by a colchicine-induced cell cycle disturbance in partially hepatectomized rats. | Cancer research 19960801 |
Reversibility of promoter induced hepatic focal lesion growth in mice. | Carcinogenesis 19960701 |
Dose dependence of phenobarbital promotion of preneoplastic hepatic lesions in F344 rats and B6C3F1 mice: effects on DNA synthesis and apoptosis. | Carcinogenesis 19960501 |
The effect of tamoxifen and two of its non-isomerizable fixed-ring analogs on multistage rat hepatocarcinogenesis. | Carcinogenesis 19960301 |
Increased oxidative DNA damage in livers of 2,3,7,8-tetrachlorodibenzo-p-dioxin treated intact but not ovariectomized rats. | Cancer letters 19960102 |
Phenobarbital selectively promotes initiated cells with reduced TGF beta receptor levels. | Carcinogenesis 19960101 |
Immunohistochemical demonstration of the gap junctional protein connexin 32 and proliferating cell nuclear antigen in glutathione S-transferase placental form-negative lesions of rat liver induced by diethylnitrosamine and clofibrate. | Toxicologic pathology 19960101 |
Inhibitory effects of 1-O-hexyl-2,3,5-trimethylhydroquinone (HTHQ), green tea catechins and other antioxidants on 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole (Glu-P-1)-induced rat hepatocarcinogenesis and dose-dependent inhibition by HTHQ of lesion induction by Glu-P-1 or 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx). | Carcinogenesis 19951201 |
Expression of c-myc in altered hepatic foci induced in rats by various single doses of diethylnitrosamine and promotion by 0.05% phenobarbital. | Molecular carcinogenesis 19951101 |
Promotion of N-nitrosodiethylamine-initiated hepatocellular tumors and hepatoblastomas by 2,3,7,8-tetrachlorodibenzo-p-dioxin or Aroclor 1254 in C57BL/6, DBA/2, and B6D2F1 mice. | Cancer research 19951101 |
Comparison of the effects of tamoxifen and toremifene on liver and kidney tumor promotion in female rats. | Carcinogenesis 19951101 |
Quantitative analysis of multiple phenotype enzyme-altered foci in rat hepatocarcinogenesis experiments: the multipath/multistage model. | Carcinogenesis 19951001 |
Inhibitory effect of vanadium on rat liver carcinogenesis initiated with diethylnitrosamine and promoted by phenobarbital. | British journal of cancer 19950601 |
Gender-dependent differences in hepatic tumor promotion in diethylnitrosamine initiated infant B6C3F1 mice by alpha-hexachlorocyclohexane. | Journal of toxicology and environmental health 19950201 |
Analysis of the potential carcinogenicity of coffee and its related compounds in a medium-term liver bioassay of rats. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 19950101 |
Transforming growth factor-beta receptors type I, II and III in phenobarbital-promoted rat liver tumors. | Carcinogenesis 19941201 |
Evaluation of the tumor-promoting activity of two beta-adrenoreceptor blocking agents, propranolol and atenolol, in liver of Fischer 344 rats. | Carcinogenesis 19941101 |
Rapid development of hepatic tumors in transforming growth factor alpha transgenic mice associated with increased cell proliferation in precancerous hepatocellular lesions initiated by N-nitrosodiethylamine and promoted by phenobarbital. | Carcinogenesis 19940901 |
Incorporation of bromodeoxyuridine in glutathione S-transferase-positive hepatocytes during rat multistage hepatocarcinogenesis. | Carcinogenesis 19940901 |
In vitro and in vivo response of hepatocytes from hepatic nodules to the mitoinhibitory effects of phenobarbital. | Carcinogenesis 19940901 |
Initiator-specific promotion of hepatocarcinogenesis by WY-14,643 and clofibrate. | Carcinogenesis 19940801 |
C-raf expression in early rat liver tumorigenesis after promotion with polychlorinated biphenyls or phenobarbital. | Xenobiotica; the fate of foreign compounds in biological systems 19940601 |
Correlation between S-adenosyl-L-methionine content and production of c-myc, c-Ha-ras, and c-Ki-ras mRNA transcripts in the early stages of rat liver carcinogenesis. | Cancer letters 19940429 |
Decreased hepatocarcinogenic effect of diethylnitrosamine in experimentally induced liver cirrhosis in rat: delay or inhibition? | Cancer letters 19940429 |
[Acidified aspirin-induced gastric lesion in rats with hepatic cirrhosis produced by N-nitrosodiethylamine or carbon tetrachloride. Effect of aldioxa on gastric lesions]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 19940301 |
Effect of 4-acetylaminofluorene and other tumour promoters on hepatocellular growth and binucleation. | Carcinogenesis 19940201 |
Promotion of hepatocellular foci and adenomas by di(2-ethylhexyl) phthalate and phenobarbital in C3H/HeNCr mice following exposure to N-nitrosodiethylamine at 15 days of age. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 19940201 |
Tumor-promoting effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and phenobarbital in initiated weanling Sprague-Dawley rats: a quantitative, phenotypic, and ras p21 protein study. | Toxicologic pathology 19940101 |
Dissimilar frequency of hepatoblastomas and hepatic cystadenomas and adenocarcinomas arising in hepatocellular neoplasms of D2B6F1 mice initiated with N-nitrosodiethylamine and subsequently given Aroclor-1254, dichlorodiphenyltrichloroethane, or phenobarbital. | Toxicologic pathology 19940101 |
Studies of tamoxifen as a promoter of hepatocarcinogenesis in female Fischer F344 rats. | Breast cancer research and treatment 19940101 |
Multiple mechanisms are responsible for altered expression of gap junction genes during oncogenesis in rat liver. | Journal of cell science 19940101 |
Selective induction of DNA synthesis in mouse preneoplastic and neoplastic hepatic lesions after exposure to phenobarbital. | Environmental health perspectives 19931201 |
Dose response for TCDD promotion of hepatocarcinogenesis in rats initiated with DEN: histologic, biochemical, and cell proliferation endpoints. | Environmental health perspectives 19931201 |
Tumor promotion by an anticonvulsant agent, phenytoin, in mouse liver: correlation with CYP2B induction. | Carcinogenesis 19931101 |
Development of hydroxysteroid sulfotransferase-deficient lesions during hepatocarcinogenesis in rats. | Carcinogenesis 19931101 |
Frequency and DNA content of micronuclei in rat parenchymal liver cells during experimental hepatocarcinogenesis. | Carcinogenesis 19931101 |
Non-linearity of neoplastic conversion induced in rat liver by low exposures to diethylnitrosamine. | Carcinogenesis 19931001 |
TCDD-mediated changes in hepatic epidermal growth factor receptor may be a critical event in the hepatocarcinogenic action of TCDD. | Carcinogenesis 19930901 |
Increased yield in GST-P-positive liver pre-neoplastic foci induced by DENA or ENU in rats pre-treated with estradiol or tamoxifen. | International journal of cancer 19930730 |
Modifying influence of prior treatment with toxic agents on induction of preneoplastic and neoplastic lesions in a medium-term multi-organ carcinogenesis bioassay. | Teratogenesis, carcinogenesis, and mutagenesis 19930101 |
The initiation-promotion-progression model of rat hepatocarcinogenesis. | Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 19930101 |
Ovariectomy promotes the growth of altered hepatic foci after withdrawal and reintroduction of phenobarbital during hepatocarcinogenesis in rats. | European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 19921001 |
Absence of ras family point mutations at codons 12, 13 and 61 in N-ethyl-N-hydroxyethylnitrosamine- or N-nitrosomorpholine-induced renal cell tumors in rats. | Japanese journal of cancer research : Gann 19920901 |
The carcinogenic effect of methapyrilene combined with nitrosodiethylamine given to rats in low doses. | Carcinogenesis 19920701 |
Dose-response relationships for chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in a rat tumor promotion model: quantification and immunolocalization of CYP1A1 and CYP1A2 in the liver. | Cancer research 19920615 |
Effects of the oxazolidinedione anticonvulsants trimethadione and dimethadione and the barbiturate homolog 5,5-dimethylbarbituric acid on N-nitrosodiethylamine-initiated renal and hepatic carcinogenesis in the F344/NCr rat. | Archives of toxicology 19920101 |
Liver tumor promotion by the cyanobacterial cyclic peptide toxin microcystin-LR. | Journal of cancer research and clinical oncology 19920101 |
Dose-dependent enhancing effects of quinacrine on induction of preneoplastic glutathione S-transferase placental form positive liver cell foci in male F344 rats. | Carcinogenesis 19911001 |
Cell proliferation and tumour promotion by ethinyl estradiol in rat hepatocarcinogenesis. | Carcinogenesis 19910601 |
Screen of five alkyl carbamates for initiating and promoting activity in rat liver. | Cancer letters 19910401 |
Inhibitory and promoting effects of carbon tetrachloride-induced liver cirrhosis on the diethylnitrosamine hepatocarcinogenesis in rats. | Cancer letters 19910401 |
Estrogen receptor, epidermal growth factor receptor and cellular ploidy in elutriated subpopulations of hepatocytes during liver tumor promotion by 17 alpha-ethinylestradiol in rats. | Carcinogenesis 19910301 |
Different modifying responses of capsaicin in a wide-spectrum initiation model of F344 rat. | Journal of Korean medical science 19910301 |
Age-dependent induction of preneoplastic liver cell foci by 2-acetylaminofluorene, phenobarbital and acetaminophen in F344 rats initially treated with diethylnitrosamine. | Japanese journal of cancer research : Gann 19910301 |
Cytochrome P-450 isozyme pattern is related to individual susceptibility to diethylnitrosamine-induced liver cancer in rats. | Japanese journal of cancer research : Gann 19910201 |
The correlation of body growth with diethylnitrosamine-induced hepatocarcinogenesis in relation to serum insulin and somatomedin-C. | Carcinogenesis 19910201 |
Modulation of 2,3,7,8-tetrachlorodibenzo-p-dioxin and phenobarbital-induced promotion of hepatocarcinogenesis in rats by the type of diet and vitamin A deficiency. | Fundamental and applied toxicology : official journal of the Society of Toxicology 19910201 |
[Dose-response relationship of promotion by phenobarbital in rat two-stage hepatocarcinogenesis]. | Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences 19910101 |
Tumor promotion as a target for estrogen/antiestrogen effects in rat hepatocarcinogenesis. | Preventive medicine 19910101 |
Role of hepatocyte proliferation in alpha-hexachlorocyclohexane and phenobarbital tumor promotion in B6C3F1 mice. | Progress in clinical and biological research 19910101 |
Promotion of hepatocellular foci in female rats by chenodeoxycholic acid. | Carcinogenesis 19910101 |
On the mechanism of the hepatocarcinogenicity of peroxisome proliferators. | Chemico-biological interactions 19910101 |
The inhibition by methionine and choline of liver carcinoma formation in male C3H mice dosed with diethylnitrosamine and fed phenobarbital. | Carcinogenesis 19900801 |
Correlation between medium-term liver bioassay system data and results of long-term testing in rats. | Carcinogenesis 19900401 |
Dose-response relationships in promotion of rat hepatocarcinogenesis by 17 alpha-ethinylestradiol. | Journal of toxicology and environmental health 19900101 |
Reversible alteration in the expression of the gap junctional protein connexin 32 during tumor promotion in rat liver and its role during cell proliferation. | Cancer communications 19900101 |
Strain-dependent effects of phenobarbital on liver tumor promotion in inbred mice. | Progress in clinical and biological research 19900101 |
Synergistic effects of low-dose hepatocarcinogens in induction of glutathione S-transferase P-positive foci in the rat liver. | Japanese journal of cancer research : Gann 19891001 |
Strain differences in susceptibility to 2-acetylaminofluorene and phenobarbital promotion of rat hepatocarcinogenesis in a medium-term assay system: quantitation of glutathione S-transferase P-positive foci development. | Japanese journal of cancer research : Gann 19891001 |
Changes in gap junction protein (connexin 32) gene expression during rat liver carcinogenesis. | Journal of cellular biochemistry 19891001 |
Lack of promoting effect of clonazepam on the development of N-nitrosodiethylamine-initiated hepatocellular tumors in mice is correlated with its inability to inhibit cell-to-cell communication in mouse hepatocytes. | Carcinogenesis 19890901 |
Promotion of malignant 'embryonal' liver tumors by phenobarbital: increased incidence and shortened latency of hepatoblastomas in (DBA/2 x C57BL/6)F1 mice initiated with N-nitrosodiethylamine. | Carcinogenesis 19890701 |
Human liver microsomal cytochrome P-450 enzymes involved in the bioactivation of procarcinogens detected by umu gene response in Salmonella typhimurium TA 1535/pSK1002. | Cancer research 19890615 |
Induction of altered hepatocellular foci of hamster for a possible short-term assay for carcinogens. | Research communications in chemical pathology and pharmacology 19890301 |
Phenobarbital promotion in diethylnitrosamine-initiated infant B6C3F1 mice: influence of gender. | Carcinogenesis 19890301 |
Regulation of the expression of some genes for enzymes of glutathione metabolism in hepatotoxicity and hepatocarcinogenesis. | Toxicology and applied pharmacology 19890101 |
Mutations at codon 61 of the Ha-ras proto-oncogene in precancerous liver lesions of the B6C3F1 mouse. | Molecular carcinogenesis 19890101 |
Neuroendocrine dysdifferentiation and bombesin production in carcinogen-induced hepatocellular rat tumours. | Carcinogenesis 19890101 |
Inhibitory effect of tamoxifen on diethylstilbestrol-promoted hepatic tumorigenesis in male rats and its possible mechanism of action. | Japanese journal of cancer research : Gann 19881201 |
Hypolipidemic drug clofibrate promotes hepatic tumor. | Biochemistry international 19881001 |
Induction of hyperplastic liver nodules in Wistar and MRC-Wistar rats by phenobarbital and the liver carcinogens acetoxime, 1-nitroso-5,6-dihydrouracil and 3-nitroso-2-oxazolidinone. | Cancer letters 19880815 |
P-450 enzyme induction by 5-ethyl-5-phenylhydantoin and 5,5-diethylhydantoin, analogues of barbiturate tumor promoters phenobarbital and barbital, and promotion of liver and thyroid carcinogenesis initiated by N-nitrosodiethylamine in rats. | Cancer research 19880501 |
De novo deposition of laminin-positive basement membrane in vitro by normal hepatocytes and during hepatocarcinogenesis. | Hepatology (Baltimore, Md.) 19880101 |
Long-term dosing studies using mutagenic carcinogens indicate a highly significant correlation between elevations in the level of rat glutathione S-transferase P messenger RNA and liver tumours of hepatocellular origin. | The Biochemical journal 19880101 |
Effect of phenobarbital on diethylnitrosamine and dimethylnitrosamine induced hepatocellular tumors in male B6C3F1 mice. | Cancer letters 19880101 |
Dose-response relationship of diethylnitrosamine-initiated tumors in neonatal balb/c mice: effect of phenobarbital promotion. | Toxicologic pathology 19880101 |
Phenotypically selective promotion of diethylnitrosamine-initiated altered hepatocyte foci by dietary phenobarbital or a topically applied coal-derived organic mixture in male and female rats. | Cancer letters 19871030 |
Reciprocal modifying effects of isomeric forms of aminophenol on induction of neoplastic lesions in rat liver and kidney initiated by N-ethyl-N-hydroxyethylnitrosamine. | Carcinogenesis 19870901 |
Carcinogenesis by nitrosodialkylamines and azoxyalkanes given by gavage to rats and hamsters. | Cancer research 19870801 |
Inhibition of neoplastic development in rat liver, kidney, oesophagus and forestomach by 4,4'-diaminodiphenylmethane administration. | Carcinogenesis 19870501 |
The histopathology and biochemistry of phenobarbitone-induced liver nodules in C3H mice. | Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement 19870101 |
[Ethinyl estradiol and hepatocarcinogenesis. An experimental study]. | Langenbecks Archiv fur Chirurgie 19870101 |
[Characteristics of hepatocarcinogenesis after single exposure of synchronized cells of the regenerating liver to N-nitrosodiethylamine and subsequent administration of phenobarbital]. | Eksperimental'naia onkologiia 19870101 |
Modifying effects of butylated hydroxyanisole, di(2-ethylhexyl)phthalate or indomethacin on mouse hepatocarcinogenesis initiated by N-nitrosodiethylamine. | Japanese journal of cancer research : Gann 19861201 |
The phenotypic stability of altered hepatic foci: effects of withdrawal and subsequent readministration of phenobarbital. | Carcinogenesis 19861201 |
Dinitrotoluene isomer-specific enhancement of the expression of diethylnitrosamine-initiated hepatocyte foci. | Carcinogenesis 19861101 |
Lack of effect of phenobarbital on hepatocellular carcinogenesis initiated by N-nitrosodiethylamine or methylazoxymethanol acetate in male Syrian golden hamsters. | Toxicology and applied pharmacology 19861101 |
Dose-response relationship of phenobarbital promotion of diethylnitrosamine initiated tumors in rat liver. | Cancer letters 19860901 |
Anti-carcinogenic action of phenobarbital given simultaneously with diethylnitrosamine in the rat. | European journal of cancer & clinical oncology 19860901 |
Effect of timing of partial hepatectomy on the induction of preneoplastic liver foci in rats given hepatocarcinogens. | Cancer letters 19860701 |
Tumor-promoting activity of benzodiazepine tranquilizers, diazepam and oxazepam, in mouse liver. | Carcinogenesis 19860501 |
Hepatic foci of cellular and enzymatic alteration and nodules in rats treated with clofibrate or diethylnitrosamine followed by phenobarbital: their rate of onset and their reversibility. | Journal of the National Cancer Institute 19860301 |
Inhibitory effects of ethoxyquin, 4,4'-diaminodiphenylmethane and acetaminophen on rat hepatocarcinogenesis. | Japanese journal of cancer research : Gann 19860301 |
Dose-response relationships for initiation of rat liver tumours by diethylnitrosamine and promotion by phenobarbitone or alcohol. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 19860301 |
Interstrain differences in susceptibility to liver carcinogenesis initiated by N-nitrosodiethylamine and its promotion by phenobarbital in C57BL/6NCr, C3H/HeNCrMTV- and DBA/2NCr mice. | Carcinogenesis 19860201 |
Effects of ethanol on experimental hepatocarcinogenesis. | Hepatology (Baltimore, Md.) 19860101 |
Liver lesions in BALB/C mice induced by an anabolic androgen (Decadurabolin), with and without pretreatment with diethylnitrosamine. | Journal of steroid biochemistry 19860101 |
Cytotoxicity of halogenated alkanes in primary cultures of rat hepatocytes from normal, partial hepatectomized, and preneoplastic/neoplastic liver. | Toxicology and applied pharmacology 19850915 |
Promoting effects of phenobarbital and 3'-methyl-4-dimethylaminoazobenzene on the appearance of gamma-glutamyltranspeptidase positive foci in rat liver pretreated with varying doses of diethylnitrosamine. | Cancer letters 19850915 |
The quantitative analysis and stability of histochemical markers of altered hepatic foci in rat liver following initiation by diethylnitrosamine administration and promotion with phenobarbital. | Carcinogenesis 19850901 |
Comparative tumor-promoting activities of phenobarbital, amobarbital, barbital sodium, and barbituric acid on livers and other organs of male F344/NCr rats following initiation with N-nitrosodiethylamine. | Journal of the National Cancer Institute 19850201 |
Promoting effects of 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene in mouse hepatocarcinogenesis. | Carcinogenesis 19850201 |
Morphologic and cytochemical properties of mouse liver neoplasms induced by diethylnitrosamine and promoted by 4,4'-dichlorodiphenyltrichloroethane, chlordane, or heptachlor. | Toxicologic pathology 19850101 |
Different responses to phenobarbital promotion in the development of gamma-glutamyltranspeptidase-positive foci in the liver of rats initiated with diethylnitrosamine, N-hydroxy-2-acetyl-aminofluorene and aflatoxin B1. | Japanese journal of cancer research : Gann 19850101 |
Influence of a prolonged treatment with disulfiram and D(-)penicillamine on nitrosodiethylamine-induced biological and biochemical effects in rats. I. Investigations on the drug metabolizing system. | Journal of cancer research and clinical oncology 19850101 |
A CT technique to evaluate the development of carcinogen-induced neoplasia in the rat liver. | Investigative radiology 19850101 |
Effect of chronic phenobarbital administration on the gamma-glutamyl transpeptidase activity of hyperplastic liver lesions induced in rats by the Solt/Farber initiation: selection process of hepatocarcinogenesis. | Carcinogenesis 19841201 |
The tumorigenicity of 5-azacytidine in the male Fischer rat. | Carcinogenesis 19841201 |
Promotive effect of primary and secondary bile acids on the induction of gamma-glutamyl transpeptidase-positive liver cell foci as a possible endogenous factor for hepatocarcinogenesis in rats. | Gan 19841001 |
Modifying potential of thirty-one chemicals on the short-term development of gamma-glutamyl transpeptidase-positive foci in diethylnitrosamine-initiated rat liver. | Gan 19841001 |
Enhancement of hepatocarcinogenesis in female rats by ethinyl estradiol and mestranol but not estradiol. | Cancer research 19840901 |
Di(2-ethylhexyl)phthalate but not phenobarbital promotes N-nitrosodiethylamine-initiated hepatocellular proliferative lesions after short-term exposure in male B6C3F1 mice. | Cancer letters 19840801 |
Enhancement of DEN initiation of liver carcinogenesis by inhibitors of NAD+ ADP ribosyl transferase in rats. | Carcinogenesis 19840701 |
Modifying effects of butylated hydroxyanisole, ethoxyquin and acetaminophen on induction of neoplastic lesions in rat liver and kidney initiated by N-ethyl-N-hydroxyethylnitrosamine. | Carcinogenesis 19840401 |
Effect of hexachlorocyclohexane on diethylnitrosamine-induced hepatocarcinogenesis in rat and its failure to promote skin tumors on dimethylbenz[a]anthracene initiation in mouse. | Carcinogenesis 19840401 |
Effect of coadministration of phenobarbital sodium on N-nitrosodiethylamine-induced gamma-glutamyltransferase-positive foci and hepatocellular carcinoma in rats. | Journal of the National Cancer Institute 19840301 |
A comparison of the lung adenoma response in strain A/J mice after intraperitoneal and oral administration of carcinogens. | Toxicology and applied pharmacology 19840201 |
Distinction between liver neoplasm promoting and syncarcinogenic effects demonstrated by exposure to phenobarbital or diethylnitrosamine either before or after N-2-fluorenylacetamide. | Carcinogenesis 19840201 |
Dissimilar patterns of promotion by di(2-ethylhexyl)phthalate and phenobarbital of hepatocellular neoplasia initiated by diethylnitrosamine in B6C3F1 mice. | Carcinogenesis 19830801 |
Effect of simultaneous administration of clofibrate with diethylnitrosamine on hepatic tumorigenesis in the rat. | Cancer letters 19830501 |
Comparison of the promoting effects of various agents in induction of preneoplastic lesions in rat liver. | Environmental health perspectives 19830401 |
Promotion mechanism of phenobarbital and partial hepatectomy in DENA hepatocarcinogenesis cell kinetics effect. | British journal of cancer 19830401 |
Establishment of two rat hepatoma cell strains produced by a carcinogen initiation, phenobarbital promotion protocol. | In vitro 19830301 |
Phenobarbital as a promoter in the initiation/selection process of experimental rat hepatocarcinogenesis. | Carcinogenesis 19830101 |
Role of estrogens as promoters of hepatic neoplasia. | Laboratory investigation; a journal of technical methods and pathology 19820301 |
Effects of various concentrations of ethyl-alpha-p-chlorophenoxyisobutyrate (clofibrate) on diethylnitrosamine-induced hepatic tumorigenesis in the rat. | Carcinogenesis 19820101 |
Failure to discriminate initiation from promotion of liver tumors in a long-term study with the phenobarbital-type inducer alpha-hexachlorocyclohexane and the role of sustained stimulation of hepatic growth and monooxygenases. | Cancer research 19811001 |
Dose-dependent enhancing effect of phenobarbital on hepatocarcinogenesis initiated by diethylnitrosamine in the rat. | Gan 19810201 |
Inhibitory effect of 4,4'-diaminodiphenylmethane on liver, kidney and bladder carcinogenesis in rats ingesting N-ethyl-N-hydroxyethylnitrosamine or N-butyl-N-(4-hydroxybutyl) nitros-amine. | Carcinogenesis 19810101 |
Effect of phenobarbital, dichlorodiphenyltrichloroethane, and polychlorinated biphenyls on diethylnitrosamine-induced hepatocarcinogenesis. | Gan 19791201 |
Carcinogenicity of methylated derivatives of N-nitrosodiethylamine and related compounds in Sprague-Dawley rats. | Journal of the National Cancer Institute 19790201 |
Enhancement by Wy-14,643, a hepatic peroxisome proliferator, of diethylnitrosamine-initiated hepatic tumorigenesis in the rat. | British journal of cancer 19781001 |
Liver ornithine decarboxylase during phenobarbital promotion of nitrosamine carcinogenesis. | Cancer letters 19780901 |
The natural history of neoplasia. Newer insights into an old problem. | The American journal of pathology 19771101 |
[Adrenergic component in the hepatotropic, carcinogenic effect of diethylnitrosamine]. | Biulleten' eksperimental'noi biologii i meditsiny 19770401 |
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