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55-18-5

55-18-5 | N-Nitrosodiethylamine

CAS No: 55-18-5 Catalog No: AG003T8Y MDL No:MFCD00013890

Product Description

Catalog Number:
AG003T8Y
Chemical Name:
N-Nitrosodiethylamine
CAS Number:
55-18-5
Molecular Formula:
C4H10N2O
Molecular Weight:
102.1350
MDL Number:
MFCD00013890
IUPAC Name:
N,N-diethylnitrous amide
InChI:
InChI=1S/C4H10N2O/c1-3-6(4-2)5-7/h3-4H2,1-2H3
InChI Key:
WBNQDOYYEUMPFS-UHFFFAOYSA-N
SMILES:
CCN(N=O)CC
EC Number:
200-226-1
UNII:
3IQ78TTX1A
NSC Number:
132
RTECS Number:
IA3500000

Properties

Complexity:
51.7  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
102.079g/mol
Formal Charge:
0
Heavy Atom Count:
7  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
102.137g/mol
Monoisotopic Mass:
102.079g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
32.7A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.5  

Literature

Title Journal
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Downregulation of metabotropic glutamate receptor 5 inhibits hepatoma development in a neurotoxin rotenone-induced Parkinson's disease model. Toxicology letters 20180515
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Nelumbo nucifera leaf extract treatment attenuated preneoplastic lesions and oxidative stress in the livers of diethylnitrosamine-treated rats. Environmental toxicology 20171101
Downregulation of UBE2E2 in rat liver cells after hepatocarcinogen treatment facilitates cell proliferation and slowing down of DNA damage response in GST-P-expressing preneoplastic lesions. Toxicology and applied pharmacology 20171101
Hesperidin protects against chemically induced hepatocarcinogenesis via modulation of Nrf2/ARE/HO-1, PPARγ and TGF-β1/Smad3 signaling, and amelioration of oxidative stress and inflammation. Chemico-biological interactions 20171101
Vitamin D(3) supplementation attenuates the early stage of mouse hepatocarcinogenesis promoted by hexachlorobenzene fungicide. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20170901
Downregulation of TMEM70 in Rat Liver Cells After Hepatocarcinogen Treatment Related to the Warburg Effect in Hepatocarcinogenesis Producing GST-P-Expressing Proliferative Lesions. Toxicological sciences : an official journal of the Society of Toxicology 20170901
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Tea polyphenols EGCG and TF restrict tongue and liver carcinogenesis simultaneously induced by N-nitrosodiethylamine in mice. Toxicology and applied pharmacology 20160601
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Double staining of β-galactosidase with fibrosis and cancer markers reveals the chronological appearance of senescence in liver carcinogenesis induced by diethylnitrosamine. Toxicology letters 20160122
A crucial role of constitutive androstane receptor (CAR) in liver tumor development by imazalil in mice. The Journal of toxicological sciences 20160101
Hexachlorobenzene induces cell proliferation, and aryl hydrocarbon receptor expression (AhR) in rat liver preneoplastic foci, and in the human hepatoma cell line HepG2. AhR is a mediator of ERK1/2 signaling, and cell cycle regulation in HCB-treated HepG2 cells. Toxicology 20151002
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Involvement of constitutive androstane receptor in liver hypertrophy and liver tumor development induced by triazole fungicides. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20150401
Farnesoid X receptor antagonizes JNK signaling pathway in liver carcinogenesis by activating SOD3. Molecular endocrinology (Baltimore, Md.) 20150201
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Promoter-region hypermethylation and expression downregulation of Yy1 (Yin yang 1) in preneoplastic liver lesions in a thioacetamide rat hepatocarcinogenesis model. Toxicology and applied pharmacology 20141101
Verapamil and rifampin effect on p-glycoprotein expression in hepatocellular carcinoma. Jundishapur journal of natural pharmaceutical products 20141101
Comparative gene and protein expression analyses of a panel of cytokines in acute and chronic drug-induced liver injury in rats. Toxicology 20141003
Ha-ras and β-catenin oncoproteins orchestrate metabolic programs in mouse liver tumors. International journal of cancer 20141001
Formylchromone exhibits salubrious effects against nitrosodiethylamine mediated early hepatocellular carcinogenesis in rats. Chemico-biological interactions 20140805
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Possible role of selective, irreversible, proteasome inhibitor (carfilzomib) in the treatment of rat hepatocellular carcinoma. Chemico-biological interactions 20140525
Prevention of rat liver fibrosis and carcinogenesis by coffee and caffeine. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20140201
Modifying effects of liver tumor promotion in rats subjected to co-administration of indole-3-carbinol and phenobarbital. The Journal of toxicological sciences 20140201
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Genomic models of short-term exposure accurately predict long-term chemical carcinogenicity and identify putative mechanisms of action. PloS one 20140101
Detection of initiating potential of non-genotoxic carcinogens in a two-stage hepatocarcinogenesis study in rats. The Journal of toxicological sciences 20140101
Chemically induced mouse liver tumors are resistant to treatment with atorvastatin. BMC cancer 20140101
Comprehensive analysis of DNA methylation and gene expression of rat liver in a 2-stage hepatocarcinogenesis model. The Journal of toxicological sciences 20140101
Anticarcinogenic effect of brucine in diethylnitrosamine initiated and phenobarbital-promoted hepatocarcinogenesis in rats. Chemico-biological interactions 20131125
Lycopene modulates initiation of N-nitrosodiethylamine induced hepatocarcinogenesis: studies on chromosomal abnormalities, membrane fluidity and antioxidant defense system. Chemico-biological interactions 20131125
Diphenylarsinic acid, a chemical warfare-related neurotoxicant, promotes liver carcinogenesis via activation of aryl hydrocarbon receptor signaling and consequent induction of oxidative DNA damage in rats. Toxicology and applied pharmacology 20131115
Thymoquinone inhibits cell proliferation through regulation of G1/S phase cell cycle transition in N-nitrosodiethylamine-induced experimental rat hepatocellular carcinoma. Toxicology letters 20131023
Global DNA methylation screening of liver in piperonyl butoxide-treated mice in a two-stage hepatocarcinogenesis model. Toxicology letters 20131009
Inhibitory effect of α-lipoic acid on thioacetamide-induced tumor promotion through suppression of inflammatory cell responses in a two-stage hepatocarcinogenesis model in rats. Chemico-biological interactions 20130925
Myrtenal ameliorates diethylnitrosamine-induced hepatocarcinogenesis through the activation of tumor suppressor protein p53 and regulation of lysosomal and mitochondrial enzymes. Fundamental & clinical pharmacology 20130801
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Hepatocyte nuclear factor 4 alpha deletion promotes diethylnitrosamine-induced hepatocellular carcinoma in rodents. Hepatology (Baltimore, Md.) 20130601
Matrix metalloproteinase Mmp-1a is dispensable for normal growth and fertility in mice and promotes lung cancer progression by modulating inflammatory responses. The Journal of biological chemistry 20130517
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Effect of enzymatically modified isoquercitrin on preneoplastic liver cell lesions induced by thioacetamide promotion in a two-stage hepatocarcinogenesis model using rats. Toxicology 20130308
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Garlic oil attenuated nitrosodiethylamine-induced hepatocarcinogenesis by modulating the metabolic activation and detoxification enzymes. International journal of biological sciences 20130101
Different pathways of constitutive androstane receptor-mediated liver hypertrophy and hepatocarcinogenesis in mice treated with piperonyl butoxide or decabromodiphenyl ether. Toxicologic pathology 20130101
Liver tumor promoting effect of orphenadrine in rats and its possible mechanism of action including CAR activation and oxidative stress. The Journal of toxicological sciences 20130101
Enhanced liver tumor promotion activity in rats subjected to combined administration of phenobarbital and orphenadrine. The Journal of toxicological sciences 20130101
Suppressive effect of liver tumor-promoting activities in rats subjected to combined administration of phenobarbital and piperonyl butoxide. The Journal of toxicological sciences 20130101
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Effect of two selenium sources on hepatocarcinogenesis and several angiogenic cytokines in diethylnitrosamine-induced hepatocarcinoma rats. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20121001
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Hepatitis B virus alters the antioxidant system in transgenic mice and sensitizes hepatocytes to Fas signaling. PloS one 20120101
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Threshold dose of liver tumor promoting effect of β-naphthoflavone in rats. The Journal of toxicological sciences 20120101
Circulating tumor cells measurements in hepatocellular carcinoma. International journal of hepatology 20120101
β-Catenin loss in hepatocytes promotes hepatocellular cancer after diethylnitrosamine and phenobarbital administration to mice. PloS one 20120101
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Enhanced liver tumor promotion but not liver initiation activity in rats subjected to combined administration of omeprazole and β-naphthoflavone. The Journal of toxicological sciences 20120101
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Increased expression of epithelial cell adhesion molecule (EpCAM) in rat hepatic tumors induced by diethylnitrosamine. Asian Pacific journal of cancer prevention : APJCP 20120101
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The effect of N-nitrosodimethylamine (NDMA) on Bax and Mcl-1 expression in human neutrophils. Bulletin of environmental contamination and toxicology 20111201
Assessment of genotoxicity induced by 7,12-dimethylbenz(a)anthracene or diethylnitrosamine in the Pig-a, micronucleus and Comet assays integrated into 28-day repeat dose studies. Environmental and molecular mutagenesis 20111201
Differential biodistribution of oncolytic poxvirus administered systemically in an autochthonous model of hepatocellular carcinoma. The journal of gene medicine 20111201
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The protective effects of fish oil and artichoke on hepatocellular carcinoma in rats. European review for medical and pharmacological sciences 20111201
Concordance between Results of Medium-term Liver Carcinogenesis Bioassays and Long-term Findings for Carcinogenic 2-Nitropropane and Non-carcinogenic1-Nitropropane in F344 Rats. Journal of toxicologic pathology 20111201
The human lung adenocarcinoma cell line EKVX produces an infectious xenotropic murine leukemia virus. Viruses 20111201
Selenium supplementation reduced oxidative stress in diethylnitrosamine-induced hepatocellular carcinoma in rats. Pakistan journal of biological sciences : PJBS 20111201
Preclinical renal cancer chemopreventive efficacy of geraniol by modulation of multiple molecular pathways. Toxicology 20111128
Medium-term multi-organ carcinogenesis bioassay of ethyl tertiary-butyl ether in rats. Toxicology 20111118
Anthocyanin-rich black currant (Ribes nigrum L.) extract affords chemoprevention against diethylnitrosamine-induced hepatocellular carcinogenesis in rats. The Journal of nutritional biochemistry 20111101
Expression of c-jun is not mandatory for mouse hepatocyte proliferation induced by two nuclear receptor ligands: TCPOBOP and T3. Journal of hepatology 20111101
Suppressive effect of enzymatically modified isoquercitrin on phenobarbital-induced liver tumor promotion in rats. Archives of toxicology 20111101
Folic acid supplementation during early hepatocarcinogenesis: cellular and molecular effects. International journal of cancer 20111101
Non-invasive monitoring of hepatocellular carcinoma in transgenic mouse with bioluminescent imaging. Cancer letters 20111101
Development and evaluation of a genomic signature for the prediction and mechanistic assessment of nongenotoxic hepatocarcinogens in the rat. Toxicological sciences : an official journal of the Society of Toxicology 20111101
Effect of some naturally occurring iron ion chelators on the formation of radicals in the reaction mixtures of rat liver microsomes with ADP, Fe and NADPH. Journal of clinical biochemistry and nutrition 20111101
[Studies on tea and health]. Wei sheng yan jiu = Journal of hygiene research 20111101
Senescence marker protein 30 (SMP30)/regucalcin (RGN) expression decreases with aging, acute liver injuries and tumors in zebrafish. Biochemical and biophysical research communications 20111022
Occurrence of nine nitrosamines and secondary amines in source water and drinking water: Potential of secondary amines as nitrosamine precursors. Water research 20111015
N-Nitrosodiethylamine genotoxicity in primary rat hepatocytes: effects of cytochrome P450 induction by phenobarbital. Toxicology letters 20111010
N-nitrosodiethylamine genotoxicity evaluation: a cytochrome P450 induction study in rat hepatocytes. Genetics and molecular research : GMR 20111005
RB and p53 cooperate to prevent liver tumorigenesis in response to tissue damage. Gastroenterology 20111001
PUMA-mediated apoptosis drives chemical hepatocarcinogenesis in mice. Hepatology (Baltimore, Md.) 20111001
Biotransformation of nitrosamines and precursor secondary amines under methanogenic conditions. Environmental science & technology 20111001
Effects of raspberry phytochemical extract on cell proliferation, apoptosis, and serum proteomics in a rat model. Journal of food science 20111001
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Genotoxic evaluation of the non-halogenated disinfection by-products nitrosodimethylamine and nitrosodiethylamine. Journal of hazardous materials 20110130
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Inhibitory effects of Indigofera aspalathoides on 20-methylcholanthrene-induced chemical carcinogenesis in rats. Journal of carcinogenesis 20110101
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Evaluation of genetic damage induced by glyphosate isopropylamine salt using Tradescantia bioassays. Genetics and molecular biology 20110101
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Evaluation of cytotoxicity and genotoxicity of some Philippine medicinal plants. Pharmacognosy magazine 20110101
Targeting insulin-like growth factor axis in hepatocellular carcinoma. Journal of hematology & oncology 20110101
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Emblica officinalis Gaertn. attentuates N-nitrosodiethylamine-induced apoptosis, autophagy, and inflammation in rat livers. Journal of medicinal food 20110101
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Gene expression study using real-time PCR identifies an NTR gene as a major marker of resistance to benzonidazole in Trypanosoma cruzi. Parasites & vectors 20110101
Association of HLA-B*5801 allele and allopurinol-induced Stevens Johnson syndrome and toxic epidermal necrolysis: a systematic review and meta-analysis. BMC medical genetics 20110101
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Scientific basis for the therapeutic use of Cymbopogon citratus, stapf (Lemon grass). Journal of advanced pharmaceutical technology & research 20110101
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CpG island hypermethylation of multiple tumor suppressor genes associated with loss of their protein expression during rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine. Biochemical and biophysical research communications 20101119
The Salmonella mutagenicity assay: the stethoscope of genetic toxicology for the 21st century. Environmental health perspectives 20101101
Genotoxic and carcinogenic risks associated with the dietary consumption of repeatedly heated coconut oil. The British journal of nutrition 20101101
Determination of volatile nitrosamines in various meat products using comprehensive gas chromatography-nitrogen chemiluminescence detection. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20101101
Comparative chronic liver toxicity of benzo[a]pyrene in two populations of the atlantic killifish (Fundulus heteroclitus) with different exposure histories. Environmental health perspectives 20101001
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Preparation of 177Lu-labeled oxine in lipiodol as a possible agent for therapy of hepatocellular carcinoma: a preliminary animal study. Cancer biotherapy & radiopharmaceuticals 20101001
Attenuation of N-nitrosodiethylamine-induced liver fibrosis by high-molecular-weight fucoidan derived from Cladosiphon okamuranus. Journal of gastroenterology and hepatology 20101001
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DNA instability at chromosomal fragile sites in cancer. Current genomics 20100801
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Resistance to cisplatin-induced apoptosis via PI3K-dependent survivin expression in a rat hepatoma cell line. International journal of oncology 20100701
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Guidelines for the welfare and use of animals in cancer research. British journal of cancer 20100525
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Tumor promotion by copper-overloading and its enhancement by excess iron accumulation involving oxidative stress responses in the early stage of a rat two-stage hepatocarcinogenesis model. Chemico-biological interactions 20100514
Beneficial effect of metronomic chemotherapy on tumor suppression and survival in a rat model of hepatocellular carcinoma with liver cirrhosis. Cancer chemotherapy and pharmacology 20100501
Chemopreventive effect of bacoside A on N-nitrosodiethylamine-induced hepatocarcinogenesis in rats. Journal of cancer research and clinical oncology 20100501
What role for biologically based dose-response models in estimating low-dose risk? Environmental health perspectives 20100501
Accelerated liver regeneration and hepatocarcinogenesis in mice overexpressing serine-45 mutant beta-catenin. Hepatology (Baltimore, Md.) 20100501
Quantitative multiparametric PROPELLER MRI of diethylnitrosamine-induced hepatocarcinogenesis in wister rat model. Journal of magnetic resonance imaging : JMRI 20100501
Preventive effect of JTE-522, a selective cyclooxygenase-2 inhibitor, on DEN-induced hepatocarcinogenesis in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100501
Hepatic oval cells activated by hepatocyte apoptosis in diethylnitrosamine-induced rat liver cirrhosis. Saudi medical journal 20100501
Evaluation of a liver micronucleus assay in young rats (IV): a study using a double-dosing/single-sampling method by the Collaborative Study Group for the Micronucleus Test (CSGMT)/Japanese Environmental Mutagen Society (JEMS)-Mammalian Mutagenicity Study Group (MMS). Mutation research 20100430
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Induction of GST-P-positive proliferative lesions facilitating lipid peroxidation with possible involvement of transferrin receptor up-regulation and ceruloplasmin down-regulation from the early stage of liver tumor promotion in rats. Archives of toxicology 20100401
Analysis of nitrosamines migration from condoms in the chinese market using a proper migration experiment. Bulletin of environmental contamination and toxicology 20100401
An approach to the study of gene expression in hepatocarcinogenesis initiation. Translational oncology 20100401
Supplementation of selenium reduces chemical hepatocarcinogenesis in male Sprague-Dawley rats. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20100401
Nuclear factor-kappa B as a promising target for selenium chemoprevention in rat hepatocarcinogenesis. Journal of gastroenterology and hepatology 20100401
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Oxidation of N-Nitrosoalkylamines by human cytochrome P450 2A6: sequential oxidation to aldehydes and carboxylic acids and analysis of reaction steps. The Journal of biological chemistry 20100312
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Induction of p53 renders ATM-deficient mice refractory to hepatocarcinogenesis. Gastroenterology 20100301
Integration of in vivo genotoxicity and short-term carcinogenicity assays using F344 gpt delta transgenic rats: in vivo mutagenicity of 2,4-diaminotoluene and 2,6-diaminotoluene structural isomers. Toxicological sciences : an official journal of the Society of Toxicology 20100301
Cytokeratin 8/18 is a useful immunohistochemical marker for hepatocellular proliferative lesions in mice. The Journal of veterinary medical science 20100301
Bacoside A downregulates matrix metalloproteinases 2 and 9 in DEN-induced hepatocellular carcinoma. Cell biochemistry and function 20100301
Screening of N-nitrosamines in tap and swimming pool waters using fast gas chromatography. Journal of separation science 20100301
No Mutations of Lysophosphatidic Acid Receptor Genes in Lung Adenocarcinomas Induced by N-Nitrosobis(2-hydroxypropyl)amine in Rats. Journal of toxicologic pathology 20100301
Antioxidant enzymatically modified isoquercitrin suppresses the development of liver preneoplastic lesions in rats induced by beta-naphthoflavone. Toxicology 20100209
The role of two putative nitroreductases, Frm2p and Hbn1p, in the oxidative stress response in Saccharomyces cerevisiae. Yeast (Chichester, England) 20100201
Dietary supplementation with branched-chain amino acids suppresses diethylnitrosamine-induced liver tumorigenesis in obese and diabetic C57BL/KsJ-db/db mice. Cancer science 20100201
Transcription coactivator PBP/MED1-deficient hepatocytes are not susceptible to diethylnitrosamine-induced hepatocarcinogenesis in the mouse. Carcinogenesis 20100201
Antioxidant enzymatically modified isoquercitrin or melatonin supplementation reduces oxidative stress-mediated hepatocellular tumor promotion of oxfendazole in rats. Archives of toxicology 20100201
Evaluation of the protective effect of ascorbic acid on nitrite- and nitrosamine-induced cytotoxicity and genotoxicity in human hepatoma line. Toxicology mechanisms and methods 20100201
Elevation of cell proliferation via generation of reactive oxygen species by piperonyl butoxide contributes to its liver tumor-promoting effects in mice. Archives of toxicology 20100201
The threshold dose for liver tumor promoting effects of dicyclanil in ICR mice. The Journal of toxicological sciences 20100201
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Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression. Cell 20100122
BRE over-expression promotes growth of hepatocellular carcinoma. Biochemical and biophysical research communications 20100115
Unique impact of RB loss on hepatic proliferation: tumorigenic stresses uncover distinct pathways of cell cycle control. The Journal of biological chemistry 20100108
Efficacy of lanreotide in preventing the occurrence of chemically induced hepatocellular carcinoma in rats. Chemico-biological interactions 20100105
Anti-angiogenic therapy on hepatocellular carcinoma development and progression. The Journal of surgical research 20100101
Effect of antisense oligomer in controlling c-raf.1 overexpression during diethylnitrosamine-induced hepatocarcinogenesis in rat. Cancer chemotherapy and pharmacology 20100101
Antioxidant and antimutagenic effect of quercetin against DEN induced hepatotoxicity in rat. Phytotherapy research : PTR 20100101
Insulin-independent promotion of chemically induced hepatocellular tumor development in genetically diabetic mice. Cancer science 20100101
Cytokeratin 8/18 as a new marker of mouse liver preneoplastic lesions. Toxicology and applied pharmacology 20100101
Rat medium-term multi-organ carcinogenesis bioassay of Agaricus blazei Murrill fruit-body extract. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101
The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis. Cancer research 20100101
Carbogen gas-challenge BOLD MR imaging in a rat model of diethylnitrosamine-induced liver fibrosis. Radiology 20100101
Inhibition of poly adenosine diphosphate-ribose polymerase decreases hepatocellular carcinoma growth by modulation of tumor-related gene expression. Hepatology (Baltimore, Md.) 20100101
Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo. PLoS genetics 20100101
The liver-selective thyromimetic T-0681 influences reverse cholesterol transport and atherosclerosis development in mice. PloS one 20100101
Inhibition by licorice flavonoid oil of glutathione S-transferase-positive foci in the medium-term rat hepatocarcinogenesis bioassay. Nutrition research (New York, N.Y.) 20100101
Effect of selenium-enriched malt on VEGF and several relevant angiogenic cytokines in diethylnitrosamine-induced hepatocarcinoma rats. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20100101
Comparison of lung cancer cell lines representing four histopathological subtypes with gene expression profiling using quantitative real-time PCR. Cancer cell international 20100101
Maternal characteristics associated with the dietary intake of nitrates, nitrites, and nitrosamines in women of child-bearing age: a cross-sectional study. Environmental health : a global access science source 20100101
The AP-1 repressor protein, JDP2, potentiates hepatocellular carcinoma in mice. Molecular cancer 20100101
Early limited nitrosamine exposures exacerbate high fat diet-mediated type 2 diabetes and neurodegeneration. BMC endocrine disorders 20100101
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Nuclear translocation of telomerase reverse transcriptase: a critical process in chemical induced hepatocellular carcinogenesis. Neoplasma 20100101
Nuclear receptor CAR represses TNFalpha-induced cell death by interacting with the anti-apoptotic GADD45B. PloS one 20100101
Cyanobacterial cyclopeptides as lead compounds to novel targeted cancer drugs. Marine drugs 20100101
PPARalpha: energy combustion, hypolipidemia, inflammation and cancer. Nuclear receptor signaling 20100101
Cruciferous vegetable intake is inversely associated with lung cancer risk among smokers: a case-control study. BMC cancer 20100101
Application of magnetic resonance imaging in transgenic and chemical mouse models of hepatocellular carcinoma. Molecular cancer 20100101
Differential chemosensitization of P-glycoprotein overexpressing K562/Adr cells by withaferin A and Siamois polyphenols. Molecular cancer 20100101
Effect of allyl isothiocyanate (AITC) in both nitrite- and nitrosamine-induced cell death, production of reactive oxygen species, and DNA damage by the single-cell gel electrophoresis (SCGE): does it have any protective effect on HepG2 cells? International journal of toxicology 20100101
Chemopreventive potential of beta-Sitosterol in experimental colon cancer model--an in vitro and In vivo study. BMC complementary and alternative medicine 20100101
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[O-aminoazotoluene inhibits DENA-induced hepatocarcinogenesis when used together in mice]. Voprosy onkologii 20100101
Stress as a possible mechanism in melanoma progression. Dermatology research and practice 20100101
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Mouse model of carbon tetrachloride induced liver fibrosis: Histopathological changes and expression of CD133 and epidermal growth factor. BMC gastroenterology 20100101
Lack of guanylate cyclase C results in increased mortality in mice following liver injury. BMC gastroenterology 20100101
Anticancer activity of a sub-fraction of dichloromethane extract of Strobilanthes crispus on human breast and prostate cancer cells in vitro. BMC complementary and alternative medicine 20100101
Serum N-glycome biomarker for monitoring development of DENA-induced hepatocellular carcinoma in rat. Molecular cancer 20100101
Role of nicotinamide in DNA damage, mutagenesis, and DNA repair. Journal of nucleic acids 20100101
Kinetics of angiogenic changes in a new mouse model for hepatocellular carcinoma. Molecular cancer 20100101
Coactivators in PPAR-Regulated Gene Expression. PPAR research 20100101
Phyllanthus spp. induces selective growth inhibition of PC-3 and MeWo human cancer cells through modulation of cell cycle and induction of apoptosis. PloS one 20100101
SOCS1, a Negative Regulator of Cytokine Signals and TLR Responses, in Human Liver Diseases. Gastroenterology research and practice 20100101
Ginger ingredients inhibit the development of diethylnitrosoamine induced premalignant phenotype in rat chemical hepatocarcinogenesis model. BioFactors (Oxford, England) 20100101
Genetic composition of laboratory stocks of the self-fertilizing fish Kryptolebias marmoratus: a valuable resource for experimental research. PloS one 20100101
TLRs, NF-κB, JNK, and Liver Regeneration. Gastroenterology research and practice 20100101
Protective effects and potential mechanisms of Pien Tze Huang on cerebral chronic ischemia and hypertensive stroke. Chinese medicine 20100101
Thymoquinone attenuates diethylnitrosamine induction of hepatic carcinogenesis through antioxidant signaling. Oxidative medicine and cellular longevity 20100101
Genomic analysis of microRNA time-course expression in liver of mice treated with genotoxic carcinogen N-ethyl-N-nitrosourea. BMC genomics 20100101
How many antiviral small interfering RNAs may be encoded by the mammalian genomes? Biology direct 20100101
Fresh raspberry phytochemical extract inhibits hepatic lesion in a Wistar rat model. Nutrition & metabolism 20100101
Chemopreventive and hepatoprotective effects of embelin on N-nitrosodiethylamine and carbon tetrachloride induced preneoplasia and toxicity in rat liver. Asian Pacific journal of cancer prevention : APJCP 20100101
NF-κB, JNK, and TLR Signaling Pathways in Hepatocarcinogenesis. Gastroenterology research and practice 20100101
Protective effect of Cassia fistula Linn. on diethylnitrosamine induced hepatocellular damage and oxidative stress in ethanol pretreated rats. Biological research 20100101
Oxidative stress induced by lead and antioxidant potential of certain adaptogens in poultry. Toxicology international 20100101
MicroRNAs involved in neoplastic transformation of liver cancer stem cells. Journal of experimental & clinical cancer research : CR 20100101
Oral methylthioadenosine administration attenuates fibrosis and chronic liver disease progression in Mdr2-/- mice. PloS one 20100101
Doxorubicin toxicity can be ameliorated during antioxidant L-carnitine supplementation. Oxidative medicine and cellular longevity 20100101
TLRs, Alcohol, HCV, and Tumorigenesis. Gastroenterology research and practice 20100101
Anti-mutagenic and anti-carcinogenic potential of the carotenoid meso-zeaxanthin. Asian Pacific journal of cancer prevention : APJCP 20100101
A comparison of the cytotoxic potential of standardized aqueous and ethanolic extracts of a polyherbal mixture comprised of Nigella sativa (seeds), Hemidesmus indicus (roots) and Smilax glabra (rhizome). Pharmacognosy research 20100101
Solanum trilobatum in the management of atopy: Through inhibition of mast cell degranulation and moderation of release of interleukins. Pharmacognosy research 20100101
Curcumin-the paradigm of a multi-target natural compound with applications in cancer prevention and treatment. Toxins 20100101
Changes of splenic macrophage during the process of liver cancer induced by diethylnitrosamine in rats. Chinese medical journal 20091220
Diethylnitrosamine (DEN) induces irreversible hepatocellular carcinogenesis through overexpression of G1/S-phase regulatory proteins in rat. Toxicology letters 20091215
Inhibitory effect of tea polyphenols on hepatic preneoplastic foci in Wistar rats. Investigational new drugs 20091201
Effect of selenium-enriched malt on hypoglycemia and regulatory hormones in diethylnitrosamine-induced hepatocarcinoma SD rats. Research in veterinary science 20091201
A computer-aided diagnostic system to discriminate SPIO-enhanced magnetic resonance hepatocellular carcinoma by a neural network classifier. Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society 20091201
N-Nitrosopiperidine and N-Nitrosodibutylamine induce apoptosis in HepG2 cells via the caspase dependent pathway. Cell biology international 20091201
Potassium bromate enhances N-ethyl-N-hydroxyethylnitrosamine-induced kidney carcinogenesis only at high doses in Wistar rats: indication of the existence of an enhancement threshold. Toxicologic pathology 20091201
Circadian disruption in experimental cancer processes. Integrative cancer therapies 20091201
Liver cell transformation in chronic HBV infection. Viruses 20091201
Cyclooxygenase 2 and Prostaglandin E2 are not Involved in N-Nitrosodiethylamine-Initiated Early Rat Hepatocarcinogenesis. Journal of toxicologic pathology 20091201
Characteristic upregulation of glucose-regulated protein 78 in an early lesion negative for hitherto established cytochemical markers in rat hepatocarcinogenesis. Journal of toxicologic pathology 20091201
Hepatoprotective activity of bacoside A against N-nitrosodiethylamine-induced liver toxicity in adult rats. Cell biology and toxicology 20091001
A diet rich in cocoa attenuates N-nitrosodiethylamine-induced liver injury in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20091001
Mechanistic study on hepatocarcinogenesis of piperonyl butoxide in mice. Toxicologic pathology 20091001
In vitro antioxidant and antihyperlipidemic activities of Bauhinia variegata Linn. Indian journal of pharmacology 20091001
Hepatoprotective and anti-hepatocarcinogenic effects of glycyrrhizin and matrine. Chemico-biological interactions 20090914
Potential chemoprevention of N-nitrosodiethylamine-induced hepatocarcinogenesis by polyphenolics from Acacia nilotica bark. Chemico-biological interactions 20090914
Measuring microenvironment mechanical stress of rat liver during diethylnitrosamine induced hepatocarcinogenesis by atomic force microscope. Microscopy research and technique 20090901
Detection and toxicity assessment of nitrosamines migration from latex gloves in the Chinese market. International journal of hygiene and environmental health 20090901
[Differentially expressed proteins in the precancerous stage of rat hepatocarcinogenesis induced by diethylnitrosamine]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090901
Expression of intercellular adhesion molecule-1 in the livers of rats treated with diethylnitrosamine. Journal of clinical biochemistry and nutrition 20090901
[Inhibitory effect of thyroxine on late stages of hepatocarcinogenesis induced in suckling mice by diethylnitrosamine]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20090901
Dynamic changes in DNA methylation during multistep rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine. Toxicology letters 20090825
Morin regulates the expression of NF-kappaB-p65, COX-2 and matrix metalloproteinases in diethylnitrosamine induced rat hepatocellular carcinoma. Chemico-biological interactions 20090814
The mysterious steps in carcinogenesis. British journal of cancer 20090804
DNA-repair genes and vitamin E in the prevention of N-nitrosodiethylamine mutagenicity. Cell biology and toxicology 20090801
Chemopreventive potential of Epoxy clerodane diterpene from Tinospora cordifolia against diethylnitrosamine-induced hepatocellular carcinoma. Investigational new drugs 20090801
The constitutive active/androstane receptor facilitates unique phenobarbital-induced expression changes of genes involved in key pathways in precancerous liver and liver tumors. Toxicological sciences : an official journal of the Society of Toxicology 20090801
Antioxidant Effect of CoQ(10) on N-nitrosodiethylamine-induced Oxidative Stress in Mice. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20090801
Protective role of chickpea seed coat fibre on N-nitrosodiethylamine-induced toxicity in hypercholesterolemic rats. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20090701
Maté attenuates DNA damage and carcinogenesis induced by diethylnitrosamine and thermal injury in rat esophagus. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090701
Cytokeratin 8/18 overexpression and complex formation as an indicator of GST-P positive foci transformation into hepatocellular carcinomas. Toxicology and applied pharmacology 20090701
The Ras inhibitor farnesylthiosalicyclic acid (FTS) prevents nodule formation and development of preneoplastic foci of altered hepatocytes in rats. European journal of cancer (Oxford, England : 1990) 20090701
Effect of Chokeberry (Aronia melanocarpa) juice on the metabolic activation and detoxication of carcinogenic N-nitrosodiethylamine in rat liver. Journal of agricultural and food chemistry 20090610
Viral hepatitis-associated intrahepatic cholangiocarcinoma shares common disease processes with hepatocellular carcinoma. British journal of cancer 20090602
Silymarin attenuated mast cell recruitment thereby decreased the expressions of matrix metalloproteinases-2 and 9 in rat liver carcinogenesis. Investigational new drugs 20090601
Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis. Molecular carcinogenesis 20090601
Inhibition of c-Jun NH2-terminal kinase switches Smad3 signaling from oncogenesis to tumor- suppression in rat hepatocellular carcinoma. Hepatology (Baltimore, Md.) 20090601
Celecoxib enhances the detoxification of diethylnitrosamine in rat liver cancer. World journal of gastroenterology 20090521
Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: inhibition of cell proliferation and induction of apoptosis. Chemico-biological interactions 20090515
Involvement of oxidative stress in hepatocellular tumor-promoting activity of oxfendazole in rats. Archives of toxicology 20090501
Echographic detection of diethylnitrosamine-induced liver tumors in rats and the effect of the intratumoral injection of an inhibitor of c-Jun N-terminal kinase. Journal of gastroenterology and hepatology 20090501
Predominant modifier of extreme liver cancer susceptibility in C57BR/cdJ female mice localized to 6 Mb on chromosome 17. Carcinogenesis 20090501
Hepatocarcinogenesis in mice with a conditional knockout of the hepatocyte growth factor receptor c-Met. International journal of cancer 20090415
Thyroid hormone receptor ligands induce regression of rat preneoplastic liver lesions causing their reversion to a differentiated phenotype. Hepatology (Baltimore, Md.) 20090401
Molecular signatures of N-nitroso compounds in Caco-2 cells: implications for colon carcinogenesis. Toxicological sciences : an official journal of the Society of Toxicology 20090401
Role of vitamin-E on rat liver-amiodarone: an ultrastructural study. Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20090401
[Inhibitory effects of Scutellaria barbate extracts on diethylnitrosamine-induced hepatocarcinoma in rats]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090401
[An improved BALB/c 3T3 cell transformation assay and its application in the cocarcinogenesis study]. Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 20090401
Protective effect of red beetroot against carbon tetrachloride- and N-nitrosodiethylamine-induced oxidative stress in rats. Journal of agricultural and food chemistry 20090325
Progression of diethylnitrosamine-induced hepatic carcinogenesis in carnitine-depleted rats. World journal of gastroenterology 20090321
Targeted deletion of hepatocyte Ikkbeta confers growth advantages. Biochemical and biophysical research communications 20090306
Tumor promoting and co-carcinogenic effects in medium-term rat hepatocarcinogenesis are not modified by co-administration of 12 pesticides in mixture at acceptable daily intake. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090301
Chemical genomics of cancer chemopreventive dithiolethiones. Carcinogenesis 20090301
[Prevention of hepatic tumor growth and metastasis in rats with rapamycin]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090301
Irradiated Chinese Rugao ham: Changes in volatile N-nitrosamine, biogenic amine and residual nitrite during ripening and post-ripening. Meat science 20090301
Biological Basis of Differential Susceptibility to Hepatocarcinogenesis among Mouse Strains. Journal of toxicologic pathology 20090301
Dose-dependent alterations in gene expression in mouse liver induced by diethylnitrosamine and ethylnitrosourea and determined by quantitative real-time PCR. Mutation research 20090219
Regulation of iron metabolism-related genes in diethylnitrosamine-induced mouse liver tumors. Toxicology letters 20090210
Hepatocarcinogenic susceptibility of rasH2 mice to troglitazone in a two-stage hepatocarcinogenesis model. Archives of toxicology 20090201
Threshold dose of piperonyl butoxide that induces reactive oxygen species-mediated hepatocarcinogenesis in rats. Archives of toxicology 20090201
Nonalcoholic steatohepatitis induced by a high-fat diet promotes diethylnitrosamine-initiated early hepatocarcinogenesis in rats. International journal of cancer 20090201
Metalloproteinases 2 and 9 activity during promotion and progression stages of rat liver carcinogenesis. Journal of molecular histology 20090201
Hepatocyte-specific activation of NF-kappaB does not aggravate chemical hepatocarcinogenesis in transgenic mice. The Journal of pathology 20090201
Inhibition of reactive oxygen species and pre-neoplastic lesions by quercetin through an antioxidant defense mechanism. Free radical research 20090201
Suppressive effect of Siraitia grosvenorii extract on dicyclanil-promoted hepatocellular proliferative lesions in male mice. The Journal of toxicological sciences 20090201
Detection and characterization of hepatocellular carcinoma in rats with liver cirrhosis: diagnostic value of combined use of MR positive and negative contrast agents. Hepatobiliary & pancreatic diseases international : HBPD INT 20090201
[The expression of B-cell translocation gene 2 in diethylnitrosamine-induced primary hepatocellular carcinoma rat model.]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090201
High mobility group box associated with cell proliferation appears to play an important role in hepatocellular carcinogenesis in rats and humans. Toxicology 20090131
Frequent mutations of lysophosphatidic acid receptor-1 gene in rat liver tumors. Mutation research 20090115
Time course evaluation of N-nitrosodialkylamines-induced DNA alkylation and oxidation in liver of mosquito fish. Mutation research 20090115
Molecular therapy for the treatment of hepatocellular carcinoma. British journal of cancer 20090113
Evaluation of a liver micronucleus assay with 12 chemicals using young rats (II): a study by the Collaborative Study Group for the Micronucleus Test/Japanese Environmental Mutagen Society-Mammalian Mutagenicity Study Group. Mutagenesis 20090101
Enhancement of preneoplastic lesion yield by Chios Mastic Gum in a rat liver medium-term carcinogenesis bioassay. Toxicology and applied pharmacology 20090101
Chemoprotective properties of rooibos (Aspalathus linearis), honeybush (Cyclopia intermedia) herbal and green and black (Camellia sinensis) teas against cancer promotion induced by fumonisin B1 in rat liver. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090101
Protective action of indole-3-acetic acid on induced hepatocarcinoma in mice. Cell biochemistry and function 20090101
Identification of N-nitrosamines in treated drinking water using nanoelectrospray ionization high-field asymmetric waveform ion mobility spectrometry with quadrupole time-of-flight mass spectrometry. Journal of chromatographic science 20090101
Keratinocytes as depository of ammonium-inducible glutamine synthetase: age- and anatomy-dependent distribution in human and rat skin. PloS one 20090101
Evaluation of centrosome abnormalities and p53 inactivation in chemical induced hepatocellular carcinogenesis. Neoplasma 20090101
In vivo evidence of hepato- and reno-protective effect of garlic oil against sodium nitrite-induced oxidative stress. International journal of biological sciences 20090101
Expression and correlation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor and microvessel density in experimental rat hepatocarcinogenesis. The Journal of international medical research 20090101
Role of the vitamin C in diethylnitrosamine-induced esophageal cancer in Wistar rats. Acta cirurgica brasileira 20090101
Preventive effect of the flavonoid, quercetin, on hepatic cancer in rats via oxidant/antioxidant activity: molecular and histological evidences. Journal of experimental & clinical cancer research : CR 20090101
Chemoprevention of rat liver toxicity and carcinogenesis by Spirulina. International journal of biological sciences 20090101
Studies on mode of action of hexaammine Co(III) chloride against diethylnitrosamine-induced hepatocarcinogenesis in mice. Journal of biochemical and molecular toxicology 20090101
Mechanisms of nitrosamine-mediated neurodegeneration: potential relevance to sporadic Alzheimer's disease. Journal of Alzheimer's disease : JAD 20090101
In vitro growth environment produces lipidomic and electron transport chain abnormalities in mitochondria from non-tumorigenic astrocytes and brain tumours. ASN neuro 20090101
Characteristic gene expression profiles in the progression from liver cirrhosis to carcinoma induced by diethylnitrosamine in a rat model. Journal of experimental & clinical cancer research : CR 20090101
Assessment of the effect of betaine on p16 and c-myc DNA methylation and mRNA expression in a chemical induced rat liver cancer model. BMC cancer 20090101
Deleted in liver cancer 2 (DLC2) was dispensable for development and its deficiency did not aggravate hepatocarcinogenesis. PloS one 20090101
Protective effects of garlic and silymarin on NDEA-induced rats hepatotoxicity. International journal of biological sciences 20090101
Circadian disruption accelerates liver carcinogenesis in mice. Mutation research 20090101
Antiviral activity of gliotoxin, gentian violet and brilliant green against Nipah and Hendra virus in vitro. Virology journal 20090101
A combination of indol-3-carbinol and genistein synergistically induces apoptosis in human colon cancer HT-29 cells by inhibiting Akt phosphorylation and progression of autophagy. Molecular cancer 20090101
Mutagenicity of Chinese traditional medicine Semen Armeniacae amarum by two modified Ames tests. BMC complementary and alternative medicine 20090101
Chitosan-alginate sponge: preparation and application in curcumin delivery for dermal wound healing in rat. Journal of biomedicine & biotechnology 20090101
Spontaneous regression of advanced hepatocellular carcinoma: a case report. Cases journal 20090101
[Diethylnitrosamine-induced carcinogenesis in PARP-1(-/-) and PARP-1(+/+) mice]. Voprosy onkologii 20090101
Nitrosamine exposure exacerbates high fat diet-mediated type 2 diabetes mellitus, non-alcoholic steatohepatitis, and neurodegeneration with cognitive impairment. Molecular neurodegeneration 20090101
The role of scavenger receptor B1 in infection with Mycobacterium tuberculosis in a murine model. PloS one 20090101
Modulatory effects of alpha- and gamma-tocopherols on 4-hydroxyestradiol induced oxidative stresses in MCF-10A breast epithelial cells. Nutrition research and practice 20090101
Ursolic acid attenuates oxidative stress-mediated hepatocellular carcinoma induction by diethylnitrosamine in male Wistar rats. Asian Pacific journal of cancer prevention : APJCP 20090101
Sida rhombifolia ssp. retusa seed extract inhibits DEN induced murine hepatic preneoplasia and carbon tetrachloride hepatotoxicity. Asian Pacific journal of cancer prevention : APJCP 20090101
Nitrosamine exposure causes insulin resistance diseases: relevance to type 2 diabetes mellitus, non-alcoholic steatohepatitis, and Alzheimer's disease. Journal of Alzheimer's disease : JAD 20090101
Hamster exhibits major differences in organ-specific metabolism of the esophageal carcinogen N-nitrosodiethylamine. Toxicology letters 20081215
Urethane and N-nitrosodiethylamine are mutagenic for the Syrian hamster fetus. Mutation research 20081208
Antiproliferative potential of gallic acid against diethylnitrosamine-induced rat hepatocellular carcinoma. Molecular and cellular biochemistry 20081201
Role of Nrf2 and oxidative stress on fenofibrate-induced hepatocarcinogenesis in rats. Toxicological sciences : an official journal of the Society of Toxicology 20081201
Protective effect of Juzen-taiho-to on hepatocarcinogenesis is mediated through the inhibition of Kupffer cell-induced oxidative stress. International journal of cancer 20081201
Hepatocarcinogenic susceptibility of fenofibrate and its possible mechanism of carcinogenicity in a two-stage hepatocarcinogenesis model of rasH2 mice. Toxicologic pathology 20081201
Altered {beta}-catenin accumulation in hepatocellular carcinomas of diethylnitrosamine-exposed rhesus macaques. Toxicologic pathology 20081201
Impact of insulin resistance on the progression of chronic liver diseases. International journal of molecular medicine 20081201
Effect of berberine on hepatocyte proliferation, inducible nitric oxide synthase expression, cytochrome P450 2E1 and 1A2 activities in diethylnitrosamine- and phenobarbital-treated rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20081101
Molecular modeling of nitrosamines adsorbed on H-ZSM-5 zeolite: an ONIOM study. Journal of molecular modeling 20081101
Pre-bled-young-rats in genotoxicity testing: a model for peripheral blood micronucleus assay. Regulatory toxicology and pharmacology : RTP 20081101
Effect of antioxidant phytochemicals on the hepatic tumor promoting activity of 3,3',4,4'-tetrachlorobiphenyl (PCB-77). Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081101
Diallyl sulfide protects against N-nitrosodiethylamine-induced liver tumorigenesis: role of aldose reductase. World journal of gastroenterology 20081028
Inhibition of the promotion of hepatocarcinogenesis by 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153) by the deletion of the p50 subunit of NF-kappa B in mice. Toxicology and applied pharmacology 20081015
Dual therapeutic effects of interferon-alpha gene therapy in a rat hepatocellular carcinoma model with liver cirrhosis. Molecular therapy : the journal of the American Society of Gene Therapy 20081001
[Changes in TGF-beta1/Smads signaling pathway in rats with chemical hepatocarcinogenesis]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20081001
Possible involvement of oxidative stress in fenofibrate-induced hepatocarcinogenesis in rats. Archives of toxicology 20080901
The effect of the aqueous extract of the roots of Asparagus racemosus on hepatocarcinogenesis initiated by diethylnitrosamine. Phytotherapy research : PTR 20080901
Antioxidant effects of flavonoids used as food additives (purple corn color, enzymatically modified isoquercitrin, and isoquercitrin) on liver carcinogenesis in a rat medium-term bioassay. Journal of food science 20080901
The protective effects of demethoxyviridine and 1-alpha-hydroxy-demethoxyviridine in the livers of male rats treated with diethylnitrosamine and 2-acetylaminflourene. Saudi medical journal 20080901
Therapeutic actions of melatonin in cancer: possible mechanisms. Integrative cancer therapies 20080901
Mutagenicity of N-nitrosodiethanolamine in a V79-derived cell line expressing two human biotransformation enzymes. Mutation research 20080825
Analysis of nitrosamines in water by automated SPE and isotope dilution GC/HRMS Occurrence in the different steps of a drinking water treatment plant, and in chlorinated samples from a reservoir and a sewage treatment plant effluent. Talanta 20080815
Hepatocyte necrosis induced by oxidative stress and IL-1 alpha release mediate carcinogen-induced compensatory proliferation and liver tumorigenesis. Cancer cell 20080812
Carcinogenic risk of copper gluconate evaluated by a rat medium-term liver carcinogenicity bioassay protocol. Archives of toxicology 20080801
Elevated activity of the oxidative and non-oxidative pentose phosphate pathway in (pre)neoplastic lesions in rat liver. International journal of experimental pathology 20080801
Mouse model of diethylnitrosamine-induced gastric cancer. The Journal of surgical research 20080801
Modifying effects of chitin, chitosan and their related compounds on 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in a rat medium-term hepatocarcinogenesis model, and their post-initiation effects in a female rat 2-stage multi-organ carcinogenesis model. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080801
Effect of carotenoids on in vitro proliferation and differentiation of oval cells during neoplastic and non-neoplastic liver injuries in rats. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080801
The use of isolated human lymphocytes in mycotoxin cytotoxicity testing. International journal of molecular sciences 20080801
Effect of in vivo loss of GDF-15 on hepatocellular carcinogenesis. Journal of cancer research and clinical oncology 20080701
Evidence that the anticarcinogenic effect of caffeic acid phenethyl ester in the resistant hepatocyte model involves modifications of cytochrome P450. Toxicological sciences : an official journal of the Society of Toxicology 20080701
Formation of N-nitrosamines from eleven disinfection treatments of seven different surface waters. Environmental science & technology 20080701
Effect of DENA induced hepatocarcinogenesis on neuroendocrine levels in male rats. Indian journal of experimental biology 20080701
Emblica officinalis and hepatocarcinogenesis: a chemopreventive study in Wistar rats. Journal of ethnopharmacology 20080619
Two-dimensional differential gel electrophoresis/analysis of diethylnitrosamine induced rat hepatocellular carcinoma. International journal of cancer 20080615
Tumor promotion in liver of mice with a conditional Cx26 knockout. Toxicological sciences : an official journal of the Society of Toxicology 20080601
Silymarin downregulates COX-2 expression and attenuates hyperlipidemia during NDEA-induced rat hepatocellular carcinoma. Molecular and cellular biochemistry 20080601
Tomato oleoresin inhibits DNA damage but not diethylnitrosamine-induced rat hepatocarcinogenesis. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20080601
Defective DNA strand break repair causes chromosomal instability and accelerates liver carcinogenesis in mice. Hepatology (Baltimore, Md.) 20080601
Intra-portal transplantation of bone marrow stromal cells ameliorates liver fibrosis in mice. Hepatobiliary & pancreatic diseases international : HBPD INT 20080601
Chemical carcinogenesis studies in nonhuman primates. Proceedings of the Japan Academy. Series B, Physical and biological sciences 20080601
Transplanted bone marrow stromal cells are not cellular origin of hepatocellular carcinomas in a mouse model of carcinogenesis. World journal of gastroenterology 20080521
Protective effects of Ginkgo biloba against rat liver carcinogenesis. Chemico-biological interactions 20080509
Possible carcinogenic risks of copper gluconate and their prevention by co-administered green tea catechins evaluated by a rat medium-term multi-organ carcinogenicity bioassay protocol. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080501
TIS21 negatively regulates hepatocarcinogenesis by disruption of cyclin B1-Forkhead box M1 regulation loop. Hepatology (Baltimore, Md.) 20080501
Concurrent administration of ascorbic acid enhances liver tumor-promoting activity of kojic acid in rats. The Journal of toxicological sciences 20080501
Potential inhibitory effects of D-allose, a rare sugar, on liver preneoplastic lesion development in F344 rat medium-term bioassay. Journal of bioscience and bioengineering 20080501
Repression of Ah receptor and induction of transforming growth factor-beta genes in DEN-induced mouse liver tumors. Toxicology 20080418
Thrombospondin-1 expression correlates with angiogenesis in experimental cirrhosis. World journal of gastroenterology 20080414
Binding of MutS protein to oligonucleotides containing a methylated or an ethylated guanine residue, and correlation with mutation frequency. Mutation research 20080402
Efficacy of doxorubicin coupled to lactosaminated albumin on rat hepatocellular carcinomas evaluated by ultrasound imaging. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20080401
N-nitrosodiethylamine-induced toxicity in relation to oxidative stress and development of atherosclerosis in hypercholesterolemic diet-fed rabbits. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20080401
Promotion potential of madder color in a medium-term multi-organ carcinogenesis bioassay model in F344 rats. Journal of food science 20080401
The differential NF-kB modulation by S-adenosyl-L-methionine, N-acetylcysteine and quercetin on the promotion stage of chemical hepatocarcinogenesis. Free radical research 20080401
[Dendritic cell vaccine modified by murine mAFP gene enhances immunoprotective effect on liver carcinogenesis and tumor development in mice]. Zhonghua zhong liu za zhi [Chinese journal of oncology] 20080401
Monitoring of N-nitrosodiethanolamine in cosmetic products by ion-pair complex liquid chromatography and identification with negative ion electrospray ionization mass spectrometry. Journal of chromatography. A 20080321
Decreased hepatic 5-HT1A receptors during liver regeneration and neoplasia in rats. Neurochemical research 20080301
Antigenotoxicity and antimutagenicity of lycopene in HepG2 cell line evaluated by the comet assay and micronucleus test. Toxicology in vitro : an international journal published in association with BIBRA 20080301
Sodium selenite enhances glutathione peroxidase activity and DNA strand breaks in hepatoma induced by N-nitrosodiethylamine and promoted by phenobarbital. Molecular and cellular biochemistry 20080301
Prevention of N-nitrosodiethylamine-induced hepatocarcinogenesis by S-allylcysteine. Molecular and cellular biochemistry 20080301
Anti-tumor effect of pegylated interferon in the rat hepatocarcinogenesis model. International journal of oncology 20080301
Effect of dietary selenium on the promotion of hepatocarcinogenesis by 3,3', 4,4'-tetrachlorobiphenyl and 2,2', 4,4', 5,5'-hexachlorobiphenyl. Experimental biology and medicine (Maywood, N.J.) 20080301
Antioxidant potential of thyme extract: alleviation of N-nitrosodiethylamine-induced oxidative stress. Human & experimental toxicology 20080301
beta-Naphthoflavone enhances oxidative stress responses and the induction of preneoplastic lesions in a diethylnitrosamine-initiated hepatocarcinogenesis model in partially hepatectomized rats. Toxicology 20080227
Persistent and remodeling hepatic preneoplastic lesions present differences in cell proliferation and apoptosis, as well as in p53, Bcl-2 and NF-kappaB pathways. Journal of cellular biochemistry 20080201
N-nitrosodimethylamine (NDMA) formation during ozonation of dimethylamine-containing waters. Water research 20080201
Differential selection for B-raf and Ha-ras mutated liver tumors in mice with high and low susceptibility to hepatocarcinogenesis. Mutation research 20080201
Inflammation, HCC and sex: IL-6 in the centre of the triangle. Journal of hepatology 20080201
Systems biological and mechanistic modelling of radiation-induced cancer. Radiation and environmental biophysics 20080201
Anti-tumor effects of cimetidine on hepatocellular carcinomas in diethylnitrosamine-treated rats. Oncology reports 20080201
Chronic ethanol intake promotes double gluthatione S-transferase/transforming growth factor-alpha-positive hepatocellular lesions in male Wistar rats. Cancer science 20080201
Attenuation of N-nitrosodiethylamine-induced hepatocellular carcinogenesis by a novel flavonol-Morin. Chemico-biological interactions 20080110
TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis. The Journal of clinical investigation 20080102
Inactivation of p27Kip1 promotes chemical mouse liver tumorigenesis in the resistant strain C57BL/6J. Molecular carcinogenesis 20080101
N-nitrosodimethylamine (NDMA) removal by reverse osmosis and UV treatment and analysis via LC-MS/MS. Water research 20080101
Alpha-lipoic acid promotes the growth of rat hepatic pre-neoplastic lesions in the choline-deficient model. Carcinogenesis 20080101
Targeting MEK is effective chemoprevention of hepatocellular carcinoma in TGF-alpha-transgenic mice. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20080101
24-hour rhythms in oxidative stress during hepatocarcinogenesis in rats: effect of melatonin or alpha-ketoglutarate. Redox report : communications in free radical research 20080101
Adenovirus vector-mediated gene therapy using iodized oil esters for hepatocellular carcinoma in rats. Anticancer research 20080101
Morphine does no promote esophageal carcinogenesis in rats exposed to diethylnitrosamine. Arquivos de gastroenterologia 20080101
The Role of PPARgamma in Hepatocellular Carcinoma. PPAR research 20080101
Reduction by dietary matrix metalloproteinase inhibitor BAY 12-9566N of neoplastic development induced by diethylnitrosamine, N-nitrosodimethylamine, or 7,12-dimethylbenz(a)anthracene in rats. Drug and chemical toxicology 20080101
Effect of black tea in diethylnitrosamine-induced esophageal carcinogenesis in mice. Acta cirurgica brasileira 20080101
Comet assay analysis of single-stranded DNA breaks in circulating leukocytes of glaucoma patients. Molecular vision 20080101
Vesicular flavonoid in combating diethylnitrosamine induced hepatocarcinoma in rat model. Journal of experimental therapeutics & oncology 20080101
Non invasive in vivo investigation of hepatobiliary structure and function in STII medaka (Oryzias latipes): methodology and applications. Comparative hepatology 20080101
Targeting aspartate aminotransferase in breast cancer. Breast cancer research : BCR 20080101
The Role of NF-kappaB in PPARalpha-Mediated Hepatocarcinogenesis. PPAR research 20080101
Diethylnitrosamine-induced hepatic lesions are greater in rats maintained under a light-dark cycle than under constant light, related to the locomotor activity rhythm. Asian Pacific journal of cancer prevention : APJCP 20080101
Modulation of energy metabolic enzyme expression in N-nitrosodiethylamine-mediated hepatocarcinogenesis by Chinese herbs, Huqi San. BioFactors (Oxford, England) 20080101
Pre- and post-initiation modulating effects of green tea ingestion on rat hepatocarcinogenesis. Nutrition research and practice 20080101
Dehydroepiandrosterone supplement increases malate dehydrogenase activity and decreases NADPH-dependent antioxidant enzyme activity in rat hepatocellular carcinogenesis. Nutrition research and practice 20080101
Interaction of N-nitrosodiethylamine/bovine serum albumin complexes with 1,2-dipalmitoyl-sn-glycero-3-phosphocholine monolayers at the air-water interface. Journal of colloid and interface science 20071215
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Inhibition of early preneoplastic events in the rat liver by the somatostatin analog lanreotide. Cancer science 20071201
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Diuron lacks promoting potential in a rat liver bioassay. Toxicologic pathology 20071201
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The effect of dietary glycine on the hepatic tumor promoting activity of polychlorinated biphenyls (PCBs) in rats. Toxicology 20071008
Comparison of mode of action of four hepatocarcinogens: a model-based approach. Toxicological sciences : an official journal of the Society of Toxicology 20071001
Prevention by melatonin of hepatocarcinogenesis in rats injected with N-nitrosodiethylamine. Journal of pineal research 20071001
Is interleukin-6 a gender-specific risk factor for liver cancer? Hepatology (Baltimore, Md.) 20071001
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Global gene expression in Ha-ras and B-raf mutated mouse liver tumors. International journal of cancer 20070915
Evaluating the impacts of membrane type, coating, fouling, chemical properties and water chemistry on reverse osmosis rejection of seven nitrosoalklyamines, including NDMA. Water research 20070901
Diethylnitrosamine initiation does not alter clofibric acid-induced hepatocarcinogenesis in the rat. Toxicological sciences : an official journal of the Society of Toxicology 20070901
Proteome analysis of chemically induced mouse liver tumors with different genotype. Proteomics 20070901
Changes in the antioxidant system by TNP-470 in an in vivo model of hepatocarcinoma. Translational research : the journal of laboratory and clinical medicine 20070901
RB loss abrogates cell cycle control and genome integrity to promote liver tumorigenesis. Gastroenterology 20070901
Enhancement of hepatocellular proliferative activity of kojic acid in mice by a simultaneous administration of ascorbic acid. The Journal of veterinary medical science 20070901
Photochemical attenuation of N-nitrosodimethylamine (NDMA) and other nitrosamines in surface water. Environmental science & technology 20070901
Effect of Qi-protecting powder (Huqi San) on expression of c-jun, c-fos and c-myc in diethylnitrosamine-mediated hepatocarcinogenesis. World journal of gastroenterology 20070821
Hepatocytes isolated from preneoplastic rat livers are resistant to ethacrynic acid cytotoxicity. Archives of toxicology 20070801
Chemotherapeutic stress selectively activates NF-kappa B-dependent AKT and VEGF expression in liver cancer-derived endothelial cells. American journal of physiology. Cell physiology 20070801
DNA damage measured by comet assay and 8-OH-dG formation related to blood chemical analyses in aged rats. The Journal of toxicological sciences 20070801
Both early and late stages of hepatocarcinogenesis are enhanced in Cx32 dominant negative mutant transgenic rats with disrupted gap junctional intercellular communication. The Journal of membrane biology 20070801
Lutein presents suppressing but not blocking chemopreventive activity during diethylnitrosamine-induced hepatocarcinogenesis and this involves inhibition of DNA damage. Chemico-biological interactions 20070720
Cell proliferation and hepatocarcinogenesis in rat initiated by diethylnitrosamine and promoted by phenobarbital: potential roles of early DNA damage and liver metallothionein expression. Life sciences 20070719
Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production. Science (New York, N.Y.) 20070706
Promoting potential of a Jamaica quassia extract in a rat medium-term hepatocarcinogenesis bioassay. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070701
Co-carcinogenic effect of cyclohexanol on the development of preneoplastic lesions in a rat hepatocarcinogenesis model. Molecular carcinogenesis 20070701
Prevention of hepatocarcinogenesis with phosphatidylcholine and menaquinone-4: in vitro and in vivo experiments. Journal of hepatology 20070701
Expression and DNA methylation patterns of Tslc1 and Dal-1 genes in hepatocellular carcinomas induced by N-nitrosodiethylamine in rats. Cancer science 20070701
The PPARgamma agonist pioglitazone inhibits early neoplastic occurrence in the rat liver. European journal of cancer (Oxford, England : 1990) 20070701
Hypoxia-inducible factor-1alpha expression in experimental cirrhosis: correlation with vascular endothelial growth factor expression and angiogenesis. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20070701
Investigating the mechanistic basis for hepatic toxicity induced by an experimental chemokine receptor 5 (CCR5) antagonist using a compendium of gene expression profiles. Toxicologic pathology 20070601
Nitrosamines as nicotinic receptor ligands. Life sciences 20070530
Molecular basis of vanadium-mediated inhibition of hepatocellular preneoplasia during experimental hepatocarcinogenesis in rats. Journal of cellular biochemistry 20070501
Analysis of nitrosamines by capillary electrospray-high-field asymmetric waveform ion mobility spectrometry-MS with programmed compensation voltage. Electrophoresis 20070501
Silymarin modulates the oxidant-antioxidant imbalance during diethylnitrosamine induced oxidative stress in rats. European journal of pharmacology 20070410
Effect of Cassia fistula Linn. leaf extract on diethylnitrosamine induced hepatic injury in rats. Chemico-biological interactions 20070405
Sodium iodide symporter is expressed at the preneoplastic stages of liver carcinogenesis and in human cholangiocarcinoma. Gastroenterology 20070401
Possible application of human c-Ha-ras proto-oncogene transgenic rats in a medium-term bioassay model for carcinogens. Toxicologic pathology 20070401
Impediment of diethylnitrosamine induced hepatotoxicity in male Balb/c mice by pretreatment with aqueous Azadirachta indica leaf extract. Indian journal of experimental biology 20070401
Anti-Cripto Mab inhibit tumour growth and overcome MDR in a human leukaemia MDR cell line by inhibition of Akt and activation of JNK/SAPK and bad death pathways. British journal of cancer 20070326
Increased 5-HT2C receptor binding in the brain stem and cerebral cortex during liver regeneration and hepatic neoplasia in rats. Journal of the neurological sciences 20070315
Interfacial behavior of N-nitrosodiethylamine/bovine serum albumin complexes at the air-water and the chloroform-water interfaces by axisymmetric drop tensiometry. The journal of physical chemistry. B 20070315
Cumulative genotoxic and apoptotic effects of xenobiotics in a mini organ culture model of human nasal mucosa as detected by the alkaline single cell microgel electrophoresis assay and the annexin V-affinity assay. Toxicology letters 20070308
Orphan nuclear receptor constitutive active/androstane receptor-mediated alterations in DNA methylation during phenobarbital promotion of liver tumorigenesis. Toxicological sciences : an official journal of the Society of Toxicology 20070301
Combined GM-CSF and IL-12 gene therapy synergistically suppresses the growth of orthotopic liver tumors. Hepatology (Baltimore, Md.) 20070301
Expression of ErbB receptor proteins and TGF-alpha during diethylnitrosamine-induced hepatocarcinogenesis in the rat liver. The Korean journal of hepatology 20070301
[Effect of 5 drugs with different antitumor mechanism on tumor-formation potential of rat hepatocarcinoma cells and mesenchymal stem cells]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20070301
Effect of silymarin on N-nitrosodiethylamine induced hepatocarcinogenesis in rats. Experimental oncology 20070301
Assessment of hemodynamics in precancerous lesion of hepatocellular carcinoma: evaluation with MR perfusion. World journal of gastroenterology 20070227
High sensitivity of fatty liver Shionogi (FLS) mice to diethylnitrosamine hepatocarcinogenesis: comparison to C3H and C57 mice. Cancer letters 20070208
Coupling of lactose molecules to the carrier protein hinders the spleen and bone marrow uptake of doxorubicin conjugated with human albumin. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070201
Evaluation of the cancer chemopreventive efficacy of rice bran in genetic mouse models of breast, prostate and intestinal carcinogenesis. British journal of cancer 20070129
A cell-penetrating ARF peptide inhibitor of FoxM1 in mouse hepatocellular carcinoma treatment. The Journal of clinical investigation 20070102
Pravastatin reduces lung metastasis of rat hepatocellular carcinoma via a coordinated decrease of MMP expression and activity. Journal of hepatology 20070101
Overexpression of cyclin D1 is associated with elevated levels of MAP kinases, Akt and Pak1 during diethylnitrosamine-induced progressive liver carcinogenesis. Cell biology international 20070101
The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450-mediated biotransformation (a corrigendum report on Duarte et al. (2005) Mutagenesis 20, 93-100). Mutagenesis 20070101
Carcinogen-induced early molecular events and its implication in the initiation of chemical hepatocarcinogenesis in rats: chemopreventive role of vanadium on this process. Biochimica et biophysica acta 20070101
Hepatitis B virus promotes hepatocarcinogenesis in transgenic mice. Hepatology (Baltimore, Md.) 20070101
Cell-cycle inhibition by TNP-470 in an in vivo model of hepatocarcinoma is mediated by a p53 and p21WAF1/CIP1 mechanism. Translational research : the journal of laboratory and clinical medicine 20070101
Bioinformatics analysis of the early inflammatory response in a rat thermal injury model. BMC bioinformatics 20070101
Effect of Bauhinia racemosa stem bark on N-nitrosodiethylamine-induced hepatocarcinogenesis in rats. The American journal of Chinese medicine 20070101
Effect of Solanum trilobatum on hepatic drug metabolising enzymes during diethylnitrosamine-induced hepatocarcinogenesis promoted by Phenobarbital in rat. Hepatology research : the official journal of the Japan Society of Hepatology 20070101
[Promoting effect of liver regeneration in hepatocarcinogenesis initiated by diethylnitrosamine in the rat]. Pathologie-biologie 20070101
Persistent activation of NF-kappaB related to IkappaB's degradation profiles during early chemical hepatocarcinogenesis. Journal of carcinogenesis 20070101
Angiogenic factor expression in hepatic cirrhosis. Mediators of inflammation 20070101
MAK-4 and -5 supplemented diet inhibits liver carcinogenesis in mice. BMC complementary and alternative medicine 20070101
Further studies on antioxidant potential and protection of pancreatic beta-cells by Embelia ribes in experimental diabetes. Experimental diabetes research 20070101
The H19 non-coding RNA is essential for human tumor growth. PloS one 20070101
Potential of Vinca rosea extracts in modulating trace element profile: a chemopreventive approach. Biological trace element research 20070101
Evidence that proteasome-dependent degradation of the retinoblastoma protein in cells lacking A-type lamins occurs independently of gankyrin and MDM2. PloS one 20070101
Effects of acetylsalicylic acid and celecoxib on the N-nitrosodiethylamine induced carcinogenesis in rat liver and esophagus. Bulletin of experimental biology and medicine 20070101
Effect of melatonin on N-nitrosodiethylamine-induced hepatocarcinogenesis in rats with reference to biochemical circadian rhythms. Toxicology mechanisms and methods 20070101
Influence of diallyl disulphide on temporal patterns of circulatory lipid peroxidation products and antioxidants in N-nitrosodiethylamine-induced hepatocarcinogenesis in rats. Toxicology mechanisms and methods 20070101
Transplantation of fetal liver epithelial progenitor cells ameliorates experimental liver fibrosis in mice. World journal of gastroenterology 20061207
Altered gene expression of transcriptional regulatory factors in tumor marker-positive cells during chemically induced hepatocarcinogenesis. Toxicology letters 20061201
Antiangiogenic effect of Lygodium flexuosum against N-nitrosodiethylamine-induced hepatotoxicity in rats. Chemico-biological interactions 20061201
Chemoprevention of bicyclol against hepatic preneoplastic lesions. Cancer biology & therapy 20061201
The oncofetal protein glypican-3 is a novel marker of hepatic progenitor/oval cells. Laboratory investigation; a journal of technical methods and pathology 20061201
In vivo 1H MR spectroscopy in the evaluation of the serial development of hepatocarcinogenesis in an experimental rat model. Academic radiology 20061201
Why cancer and inflammation? The Yale journal of biology and medicine 20061201
A single dose of caffeic acid phenethyl ester prevents initiation in a medium-term rat hepatocarcinogenesis model. World journal of gastroenterology 20061114
Mutagenicity of cytochrome P450 2E1 substrates in the Ames test with the metabolic competent S. typhimurium strain YG7108pin3ERb5. Toxicology 20061110
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. Journal of molecular graphics & modelling 20061101
Molecular basis of anticlastogenic potential of vanadium in vivo during the early stages of diethylnitrosamine-induced hepatocarcinogenesis in rats. Mutation research 20061030
Chemopreventive effect of vanadium in a rodent model of chemical hepatocarcinogenesis: reflections in oxidative DNA damage, energy-dispersive X-ray fluorescence profile and metallothionein expression. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20061001
Vanadium limits the expression of proliferating cell nuclear antigen and inhibits early DNA damage during diethylnitrosamine-induced hepatocellular preneoplasia in rats. Environmental and molecular mutagenesis 20061001
Metabolic normalization of alpha-ketoglutarate against N-nitrosodiethylamine-induced hepatocarcinogenesis in rats. Fundamental & clinical pharmacology 20061001
Evaluation of possible mechanisms of protective role of Tamarix gallica against DEN initiated and 2-AAF promoted hepatocarcinogenesis in male Wistar rats. Life sciences 20060905
PCB 153, a non-dioxin-like tumor promoter, selects for beta-catenin (Catnb)-mutated mouse liver tumors. Toxicological sciences : an official journal of the Society of Toxicology 20060901
Key issues in the modes of action and effects of trichloroethylene metabolites for liver and kidney tumorigenesis. Environmental health perspectives 20060901
Key issues in the role of peroxisome proliferator-activated receptor agonism and cell signaling in trichloroethylene toxicity. Environmental health perspectives 20060901
[A relationship between cyclooxygenase-2 expression and tumor angiogenesis in experimental rat liver carcinogenesis]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20060901
Alpha-benzene hexachloride exerts hormesis in preneoplastic lesion formation of rat hepatocarcinogenesis with the possible role for hepatic detoxifying enzymes. Cancer letters 20060818
Ablation of gap junctional communication in hepatocytes of transgenic mice does not lead to disrupted cellular homeostasis or increased spontaneous tumourigenesis. European journal of cell biology 20060801
High volume hydrodynamic injection of plasmid DNA via the hepatic artery results in a high level of gene expression in rat hepatocellular carcinoma induced by diethylnitrosamine. The journal of gene medicine 20060801
A conjugate of doxorubicin with lactosaminated albumin enhances the drug concentrations in all the forms of rat hepatocellular carcinomas independently of their differentiation grade. Liver international : official journal of the International Association for the Study of the Liver 20060801
[Correlation of antitumor drug sensitivity between marrow mesenchymal stem cells (MSCs) and hepatocarcinoma cells in rats]. Ai zheng = Aizheng = Chinese journal of cancer 20060801
Inactivation of PEMT2 in hepatocytes initiated by DENA in fasted/refed rats. Biochemical and biophysical research communications 20060721
Expression of GCIP in transgenic mice decreases susceptibility to chemical hepatocarcinogenesis. Oncogene 20060713
Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation. Proceedings of the National Academy of Sciences of the United States of America 20060711
Tumor promoting potency of PCBs 28 and 101 in rat liver. Toxicology letters 20060701
Assessment of chronic toxicity and carcinogenicity in an accelerated cancer bioassay in rats of Nifurtimox, an antitrypanosomiasis drug. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20060701
Deletion of the SOCS3 gene in liver parenchymal cells promotes hepatitis-induced hepatocarcinogenesis. Gastroenterology 20060701
[Malignant tendency of basophilic liver cells in experimental rat hepatocarcinogenesis]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20060701
Critique of dose response in carcinogenesis. Human & experimental toxicology 20060701
Adenovirus vector-mediated gene transfer using degradable starch microspheres for hepatocellular carcinoma in rats. The Journal of surgical research 20060615
Suppression of N-nitrosodiethylamine induced hepatocarcinogenesis by silymarin in rats. Chemico-biological interactions 20060610
Evaluation of nitroreductase and acetyltransferase participation in N-nitrosodiethylamine genotoxicity. Chemico-biological interactions 20060610
Concordance of thresholds for carcinogenicity of N-nitrosodiethylamine. Archives of toxicology 20060601
Protective effects of guarana (Paullinia cupana Mart. var. Sorbilis) against DEN-induced DNA damage on mouse liver. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060601
In vivo detection of free radicals induced by diethylnitrosamine in rat liver tissue. Free radical biology & medicine 20060601
Possible tumor development from double positive foci for TGF-alpha and GST-P observed in early stages on rat hepatocarcinogenesis. Cancer science 20060601
Enhancing effects of simultaneous treatment with sodium nitrite on 2-amino-3-methylimidazo[4,5-f]quinoline-induced rat liver, colon and Zymbal's gland carcinogenesis after initiation with diethylnitrosamine and 1,2-dimethylhydrazine. International journal of cancer 20060515
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Gradual upregulation of OCI-5 expression during occurrence and progression of rat hepatocellular carcinoma. Hepatobiliary & pancreatic diseases international : HBPD INT 20060501
[The biological behavior of hepatocarcinoma stem cells in rats]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20060501
Etiology of bromate-induced cancer and possible modes of action-studies in Japan. Toxicology 20060417
Essential contribution of a chemokine, CCL3, and its receptor, CCR1, to hepatocellular carcinoma progression. International journal of cancer 20060415
Kinetics and mechanisms of the reactions of hydroxyl radicals and hydrated electrons with nitrosamines and nitramines in water. The journal of physical chemistry. A 20060413
Effect of selenium-enriched malt on hepatocarcinogenesis, paraneoplastic syndrome and the hormones regulating blood glucose in rats treated by diethylnitrosamine. Life sciences 20060411
Chemoprevention and cytotoxic effect of Bauhinia variegata against N-nitrosodiethylamine induced liver tumors and human cancer cell lines. Journal of ethnopharmacology 20060406
Inhibition of hepatocarcinogenesis by the deletion of the p50 subunit of NF-kappaB in mice administered the peroxisome proliferator Wy-14,643. Toxicological sciences : an official journal of the Society of Toxicology 20060401
Early induction of TGF-beta1 through a fasting-re-feeding regimen promotes liver carcinogenesis by a sub-initiating dose of diethylnitrosamine. Cell proliferation 20060401
Genotoxicity of glycidamide in comparison to (+/-)-anti-benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide and alpha-acetoxy-N-nitroso-diethanolamine in human blood and in mammalian V79-cells. Molecular nutrition & food research 20060401
Halofuginone suppresses the lung metastasis of chemically induced hepatocellular carcinoma in rats through MMP inhibition. Neoplasia (New York, N.Y.) 20060401
[Induction of chemical hepatocarcinogenesis and establishment of orthotopic liver transplantation model with hepatocarcinoma in rats]. Zhonghua yi xue za zhi 20060328
Transplantable tumor lines generated in clonal zebrafish. Cancer research 20060315
Effects of administration of Embelin and Curcumin on lipid peroxidation, hepatic glutathione antioxidant defense and hematopoietic system during N-nitrosodiethylamine/Phenobarbital-induced hepatocarcinogenesis in Wistar rats. Molecular and cellular biochemistry 20060301
Chemopreventive effects of Paullinia cupana Mart var. sorbilis, the guaraná, on mouse hepatocarcinogenesis. Cancer letters 20060220
Ectopic activity of fibroblast growth factor receptor 1 in hepatocytes accelerates hepatocarcinogenesis by driving proliferation and vascular endothelial growth factor-induced angiogenesis. Cancer research 20060201
A dual and opposite effect of Calendula officinalis flower extract: chemoprotector and promoter in a rat hepatocarcinogenesis model. Planta medica 20060201
Nine-week detection of six genotoxic lung carcinogens using the rasH2/BHT mouse model. Cancer letters 20060118
Amelioration of carcinogenesis and tumor growth in the rat liver by combination of vitamin K2 and angiotensin-converting enzyme inhibitor via anti-angiogenic activities. Oncology reports 20060101
Antioxidant activity of Terminalia arjuna bark extract on N-nitrosodiethylamine induced hepatocellular carcinoma in rats. Molecular and cellular biochemistry 20060101
Pronounced inhibitory effect of chlorcyclizine (CCZ) in experimental hepatocarcinoma. In vivo (Athens, Greece) 20060101
Research needs in drinking water: a basis in regulations in the United States. Journal of water and health 20060101
N-nitrosodiethylamine-induced pig liver hepatocellular carcinoma model: radiological and histopathological studies. Cardiovascular and interventional radiology 20060101
Alpha-ketoglutarate modulates the circadian patterns of lipid peroxidation and antioxidant status during N-nitrosodiethylamine-induced hepatocarcinogenesis in rats. Journal of medicinal food 20060101
Effects of cessation of alcohol exposure on rat hepatocarcinogenesis. Asian Pacific journal of cancer prevention : APJCP 20060101
Catheterization of the hepatic artery via the left common carotid artery in rats. Cardiovascular and interventional radiology 20060101
A long-term investigation of the anti-hepatocarcinogenic potential of an indigenous medicine comprised of Nigella sativa, Hemidesmus indicus and Smilax glabra. Journal of carcinogenesis 20060101
Lack of promoting effects of phenobarbital at low dose on diethylnitrosamine-induced hepatocarcinogenesis in TGF-alpha transgenic mice. Asian Pacific journal of cancer prevention : APJCP 20060101
Impact of hypercholesterolemia on toxicity of N-nitrosodiethylamine: biochemical and histopathological effects. Pharmacological reports : PR 20060101
Chemopreventive activity of a macrofungus Phellinus rimosus against N-nitrosodiethylamine induced hepatocellular carcinoma in rat. Journal of experimental therapeutics & oncology 20060101
IGF-II transgenic mice display increased aberrant colon crypt multiplicity and tumor volume after 1,2-dimethylhydrazine treatment. Journal of carcinogenesis 20060101
Phytotherapeutic compound YHK exerts an inhibitory effect on early stage of experimentally-induced neoplastic liver lesions. Annals of hepatology 20060101
Gene expression analysis on the dicyclanil-induced hepatocellular tumors in mice. Toxicologic pathology 20060101
Bone disorders in experimentally induced liver disease in growing rats. World journal of gastroenterology 20051207
[Mini-organ cultures of human nasal mucosa. A model for eco-genotoxicological investigations]. HNO 20051201
Species-specific effects of the hepatocarcinogens 3'-methyl-4-dimethyl-aminoazobenzene and ortho-aminoazotoluene in mouse and rat liver. Molecular carcinogenesis 20051201
The inhibitory effect of sodium selenite on N-nitrosodiethylamine-induced and phenobarbital promoted liver tumourigenesis in rats based on the modulation of polyamine levels. Molecular and cellular biochemistry 20051201
Role of HSP90, CDC37, and CRM1 as modulators of P16(INK4A) activity in rat liver carcinogenesis and human liver cancer. Hepatology (Baltimore, Md.) 20051201
[Effect of phenobarbital and thyroxine on hepatocarcinogenesis initiated in mice by nitrosoethylurea and diethylnitrosamine]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20051201
CCAAT/enhancer binding protein alpha knock-in mice exhibit early liver glycogen storage and reduced susceptibility to hepatocellular carcinoma. Cancer research 20051115
Low dose DDT inhibition of hepatocarcinogenesis initiated by diethylnitrosamine in male rats: possible mechanisms. Toxicology and applied pharmacology 20051101
Occurrence of N-nitrosodimethylamine in South Korean and imported alcoholic beverages. Food additives and contaminants 20051101
Protective role of Vitamin E pre-treatment on N-nitrosodiethylamine induced oxidative stress in rat liver. Chemico-biological interactions 20051020
Effect of Solanum trilobatum on the antioxidant status during diethyl nitrosamine induced and phenobarbital promoted hepatocarcinogenesis in rat. Chemico-biological interactions 20051020
Investigation of the formation of N-nitrosodiethanolamine in B6C3F1 mice following topical administration of triethanolamine. Regulatory toxicology and pharmacology : RTP 20051001
Human p53 knock-in (hupki) mice do not differ in liver tumor response from their counterparts with murine p53. Carcinogenesis 20051001
Doxorubicin coupled to lactosaminated albumin inhibits the growth of hepatocellular carcinomas induced in rats by diethylnitrosamine. Journal of hepatology 20051001
NDELA and nickel modulation of triazine disposition in skin. Toxicology and industrial health 20051001
Apigenin inhibits oxidative stress-induced macromolecular damage in N-nitrosodiethylamine (NDEA)-induced hepatocellular carcinogenesis in Wistar albino rats. Molecular carcinogenesis 20050901
In vivo detection of metabolic changes by 1H-MRS in the DEN-induced hepatocellular carcinoma in Wistar rat. Journal of cancer research and clinical oncology 20050901
Chemopreventive effects of embelin and curcumin against N-nitrosodiethylamine/phenobarbital-induced hepatocarcinogenesis in Wistar rats. Fitoterapia 20050901
Overexpression of insulin receptor substrate-2 in human and murine hepatocellular carcinoma. The American journal of pathology 20050901
Assessing susceptibility from early-life exposure to carcinogens. Environmental health perspectives 20050901
Inhibitory effects of Pfaffia paniculata (Brazilian ginseng) on preneoplastic and neoplastic lesions in a mouse hepatocarcinogenesis model. Cancer letters 20050826
Melatonin modulates the oxidant-antioxidant imbalance during N-nitrosodiethylamine induced hepatocarcinogenesis in rats. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20050812
Altered retinoid metabolism in female Long-Evans and Han/Wistar rats following long-term 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-treatment. Toxicological sciences : an official journal of the Society of Toxicology 20050801
Enhanced uptake of lactosaminated human albumin by rat hepatocarcinomas: implications for an improved chemotherapy of primary liver tumors. Liver international : official journal of the International Association for the Study of the Liver 20050801
Suppression of beta-catenin mutation by dietary exposure of auraptene, a citrus antioxidant, in N,N-diethylnitrosamine-induced hepatocellular carcinomas in rats. Oncology reports 20050801
Suppression of chemically-induced liver tumors by castration or estradiol-3-benzoate treatment in F344 rats. Oncology reports 20050801
Suppression of glutathione S-transferase placental form-positive foci development in rat hepatocarcinogenesis by Chlorella pyrenoidosa. Oncology reports 20050801
Roxithromycin inhibits constitutive activation of nuclear factor {kappa}B by diminishing oxidative stress in a rat model of hepatocellular carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research 20050801
Magnetic resonance imaging of hepatocellular carcinoma induced by diethylnitrosamine in Sprague-Dawley rats. Hepatobiliary & pancreatic diseases international : HBPD INT 20050801
Chemomodulatory effect of Ficus racemosa extract against chemically induced renal carcinogenesis and oxidative damage response in Wistar rats. Life sciences 20050729
Decreased density of beta1-adrenergic receptors in preneoplastic and neoplastic liver lesions of F344 rats. Histology and histopathology 20050701
IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis. Cell 20050701
[Evaluation of early stage diffused liver lesions with MR functional diffusion-weighted imaging--an experimental study]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20050701
CT perfusion at early stage of hepatic diffuse disease. World journal of gastroenterology 20050614
Automated solid-phase extraction and high-performance liquid chromatographic determination of nitrosamines using post-column photolysis and tris(2,2'-bipyridyl) ruthenium(III) chemiluminescence. Journal of chromatography. A 20050603
Altered expression of cytochrome P450 and possible correlation with preneoplastic changes in early stage of rat hepatocarcinogenesis. Acta pharmacologica Sinica 20050601
Increased lung metastasis in transgenic NM23-Null/SV40 mice with hepatocellular carcinoma. Journal of the National Cancer Institute 20050601
Farnesyltransferase inhibitor, ABT-100, is a potent liver cancer chemopreventive agent. Clinical cancer research : an official journal of the American Association for Cancer Research 20050601
Modulation of N-nitrosodiethylamine (NDEA) induced oxidative stress by vitamin E in rat erythrocytes. Human & experimental toxicology 20050601
Comparisons of thresholds for carcinogenicity on linear and logarithmic dosage scales. Human & experimental toxicology 20050601
Effect of neonatal injection of sodium glutamate and diethylnitrosamine on hepatocarcinogenesis, reproductive and adrenocortical systems of male mice. Bulletin of experimental biology and medicine 20050601
Apoptosis in stages of mouse hepatocarcinogenesis: failure to counterbalance cell proliferation and to account for strain differences in tumor susceptibility. Toxicological sciences : an official journal of the Society of Toxicology 20050501
Interferon-gamma-mediated hepatocarcinogenesis in mice treated with diethylnitrosamine. Laboratory investigation; a journal of technical methods and pathology 20050501
Escherichia coli BTC, a human cytochrome P450 competent tester strain with a high sensitivity towards alkylating agents: involvement of alkyltransferases in the repair of DNA damage induced by aromatic amines. Mutagenesis 20050501
Deletion of Bid impedes cell proliferation and hepatic carcinogenesis. The American journal of pathology 20050501
[In vivo micronuclei and gene mutation induced by DEN in the lacZ transgenic mouse]. Wei sheng yan jiu = Journal of hygiene research 20050501
[Sodium glutamate on some physiological features and chemically induced hepatocarcinogenesis in neontal period in male mice]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20050501
Magnetic resonance diffusion-weighted imaging in the diagnosis of diffuse liver diseases in rats. Chinese medical journal 20050420
Inhibitory effect of celery seeds extract on chemically induced hepatocarcinogenesis: modulation of cell proliferation, metabolism and altered hepatic foci development. Cancer letters 20050418
AFP gene expression after acute diethylnitrosamine intoxication is not Afr2 regulated. Cancer letters 20050408
Characterization of an acute molecular marker of nongenotoxic rodent hepatocarcinogenesis by gene expression profiling in a long term clofibric acid study. Chemical research in toxicology 20050401
Different inhibitory effects in the early and late phase of treatment with KAT-681, a liver-selective thyromimetic, on rat hepatocarcinogenesis induced by 2-acetylaminofluorene and partial hepatectomy after diethylnitrosamine initiation. Toxicological sciences : an official journal of the Society of Toxicology 20050301
HMG-CoA reductase inhibitors, statins, induce phosphorylation of Mdm2 and attenuate the p53 response to DNA damage. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050301
Combination of interferon and angiotensin-converting enzyme inhibitor, perindopril, suppresses liver carcinogenesis and angiogenesis in mice. Oncology reports 20050301
Hepatitis C virus acts as a tumor accelerator by blocking apoptosis in a mouse model of hepatocarcinogenesis. Hepatology (Baltimore, Md.) 20050301
The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450 mediated biotransformation. Mutagenesis 20050301
Mass spectrometric methodology for the determination of glyoxaldeoxyguanosine and O6-hydroxyethyldeoxyguanosine DNA adducts produced by nitrosamine bident carcinogens. Chemical research in toxicology 20050301
Efficacy of Terminalia arjuna (Roxb.) on N-nitrosodiethylamine induced hepatocellular carcinoma in rats. Indian journal of experimental biology 20050301
Radiomodulatory effect of liposome encapsulated AK-2123 on tumor in mice exposed to hepatocarcinogen. Molecular and cellular biochemistry 20050301
Downregulation of apoptosis revealed by laser microdissection and cDNA microarray analysis of related genes in rat liver preneoplastic lesions. Medical molecular morphology 20050301
Modulation of liver tumorigenesis in Connexin32-deficient mouse. Mutation research 20050215
Fumagillin treatment of hepatocellular carcinoma in rats: an in vivo study of antiangiogenesis. World journal of gastroenterology 20050214
B-raf and Ha-ras mutations in chemically induced mouse liver tumors. Oncogene 20050210
Superoxide generation from Kupffer cells contributes to hepatocarcinogenesis: studies on NADPH oxidase knockout mice. Carcinogenesis 20050201
Gefitinib, an EGFR inhibitor, prevents hepatocellular carcinoma development in the rat liver with cirrhosis. Hepatology (Baltimore, Md.) 20050201
Determination of N-nitrosodiethanolamine in cosmetic products by LC-MS-MS. Analytical and bioanalytical chemistry 20050201
Chemoprevention of N-nitrosodiethylamine induced phenobarbitol promoted liver tumors in rat by extract of Indigofera aspalathoides. Biological & pharmaceutical bulletin 20050201
[Pexoxisome proliferator-activated receptor gamma ligands suppress liver carcinogenesis induced by diethylnitrosamine in rats]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20050201
Comparison of different initiation protocols in the resistant hepatocyte model. Toxicology 20050131
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Inhibition of lung tumorigenesis by tea. Experimental lung research 20050101
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Effect of proapoptosis protein on hepatocarcinogenesis. Chinese journal of digestive diseases 20050101
Characterization of insulin-like-growth factor II (IGF II) mRNA positive hepatic altered foci and IGF II expression in hepatocellular carcinoma during diethylnitrosamine-induced hepatocarcinogenesis in rats. Journal of carcinogenesis 20050101
Suppression of renin-angiotensin system attenuates hepatocarcinogenesis via angiogenesis inhibition in rats. Anticancer research 20050101
Targeting energy metabolism in brain cancer: review and hypothesis. Nutrition & metabolism 20050101
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Total antioxidant status in the blood serum of rats exposed to N-nitroso compounds and nitric oxide synthase inhibitors. Roczniki Panstwowego Zakladu Higieny 20050101
Evaluation of the carcinogenic potential of clofibrate in the neonatal mouse. International journal of toxicology 20050101
Modification of an in vivo lung metastasis model of hepatocellular carcinoma by low dose N-nitrosomorpholine and diethylnitrosamine. Clinical & experimental metastasis 20050101
A new experimental model to study preneoplastic lesions in achalasia of the esophagus. Acta cirurgica brasileira 20050101
[Ratio of low- and high-spin cytochrome P-450 in liver microsomes of N-nitrosodiethylamine-induced hepatomas]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20050101
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[Development of a rat model for primary liver cancer with modified method]. Zhonghua yi xue za zhi 20041202
Participation of BER and NER pathways in the repair of DNA lesions induced at low N-nitrosodiethylamine concentrations. Toxicology letters 20041201
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Suppression of diethylnitrosamine and 2-acetylaminofluorene-induced hepatocarcinogenesis in rats by tocotrienol-rich fraction isolated from rice bran oil. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20041201
Application of comparative functional genomics to identify best-fit mouse models to study human cancer. Nature genetics 20041201
Inherent growth advantage of (pre)malignant hepatocytes associated with nuclear translocation of pro-transforming growth factor alpha. British journal of cancer 20041129
Lack of antagonism of 2,3,7,8-tetrachlorodibenzo-p-dioxin's (TCDDs) induction of cytochrome P4501A1 (CYP1A1) by the putative selective aryl hydrocarbon receptor modulator 6-alkyl-1,3,8-trichlorodibenzofuran (6-MCDF) in the mouse hepatoma cell line Hepa-1c1c7. Chemico-biological interactions 20041120
alpha(2)-Macroglobulin: a novel cytochemical marker characterizing preneoplastic and neoplastic rat liver lesions negative for hitherto established cytochemical markers. The American journal of pathology 20041101
Long-term radioiodine retention and regression of liver cancer after sodium iodide symporter gene transfer in wistar rats. Cancer research 20041101
Further development of 32P-postlabeling for the detection of alkylphosphotriesters: evidence for the long-term nonrandom persistence of ethyl-phosphotriester adducts in vivo. Chemical research in toxicology 20041101
A modified rat model for hepatocellular carcinoma. Hepatobiliary & pancreatic diseases international : HBPD INT 20041101
The gap junction protein connexin32 is a mouse lung tumor suppressor. Cancer research 20041015
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Absence of carcinogenic and anticarcinogenic effects of annatto in the rat liver medium-term assay. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20041001
Dietary modulation of fatty acid profiles and oxidative status of rat hepatocyte nodules: effect of different n-6/n-3 fatty acid ratios. Lipids 20041001
In vivo antioxidant potential of rice bran oil (RBO) in albino rats. Indian journal of physiology and pharmacology 20041001
Enhancement of hepatocarcinogenesis by kojic acid in rat two-stage models after initiation with N-bis(2-hydroxypropyl)nitrosamine or N-diethylnitrosamine. Toxicological sciences : an official journal of the Society of Toxicology 20040901
Post-initiation modulating effects of allyl sulfides in rat hepatocarcinogenesis. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040901
Induction of preneoplastic rat liver lesions with an attenuated p53 response by low doses of diethylnitrosamine. Archives of toxicology 20040901
Inhibitory effects of KAT-681, a liver-selective thyromimetic, on development of hepatocellular proliferative lesions in rats induced by 2-acetylaminofluorene and partial hepatectomy after diethylnitrosamine initiation. Archives of toxicology 20040801
Age-related differences in susceptibility to carcinogenesis: a quantitative analysis of empirical animal bioassay data. Environmental health perspectives 20040801
Interferon alpha-induced apoptosis on rat preneoplastic liver is mediated by hepatocytic transforming growth factor beta(1). Hepatology (Baltimore, Md.) 20040801
Modulation of altered hepatic foci induction by diallyl sulphide in Wistar rats. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20040801
Disruption of sphingolipid biosynthesis in hepatocyte nodules: selective proliferative stimulus induced by fumonisin B1. Toxicology 20040715
Differentiation processes of oval cells into hepatocytes: proposals based on morphological and phenotypical traits in carcinogen-treated hamster liver. Journal of comparative pathology 20040701
Aryl hydrocarbon receptor (AhR)-independent effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on softshell clam (Mya arenaria) reproductive tissue. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20040701
Standardization of conditions for the metabolic activation of N-nitrosodiethylamine in mutagenicity tests. Genetics and molecular research : GMR 20040630
An acyclic retinoid, NIK-333, inhibits N-diethylnitrosamine-induced rat hepatocarcinogenesis through suppression of TGF-alpha expression and cell proliferation. Carcinogenesis 20040601
Bone marrow engraftment in a rodent model of chemical carcinogenesis but no role in the histogenesis of hepatocellular carcinoma. Gut 20040601
Combined supplementation of vanadium and beta-carotene suppresses placental glutathione S-transferase-positive foci and enhances antioxidant functions during the inhibition of diethylnitrosamine-induced rat liver carcinogenesis. Journal of gastroenterology and hepatology 20040601
Expression of cytochrome P4502E1 gene in hepatocellular carcinoma. World journal of gastroenterology 20040601
Halting the interaction between vascular endothelial growth factor and its receptors attenuates liver carcinogenesis in mice. Hepatology (Baltimore, Md.) 20040601
Relationship between high sensitivity of suckling mice to hepatocarcinogenic and antiglucocorticoid effects of o-aminoazotoluene and diethylnitrosamine. Bulletin of experimental biology and medicine 20040601
Initiating activity of 4-chlorobiphenyl metabolites in the resistant hepatocyte model. Toxicological sciences : an official journal of the Society of Toxicology 20040501
1alpha, 25-dihydroxyvitamin D3 prevents DNA damage and restores antioxidant enzymes in rat hepatocarcinogenesis induced by diethylnitrosamine and promoted by phenobarbital. World journal of gastroenterology 20040501
Induction of preneoplastic altered hepatic foci following dietary sulphur supplementation. Human & experimental toxicology 20040501
Heterozygous p53-deficient (+/-) mice develop fewer p53-negative preneoplastic focal liver lesions in response to treatment with diethylnitrosamine than do wild-type (+/+) mice. Cancer letters 20040430
Delayed liver regeneration and increased susceptibility to chemical hepatocarcinogenesis in transgenic mice expressing a dominant-negative mutant of connexin32 only in the liver. Carcinogenesis 20040401
Alterations of the M6p/Igf2 receptor gene in hepatocellular carcinomas induced by N-nitrosodiethylamine and a choline-deficient L-amino acid-defined diet in rats. Molecular carcinogenesis 20040401
Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor. Genes & development 20040401
Role of apoptosis for mouse liver growth regulation and tumor promotion: comparative analysis of mice with high (C3H/He) and low (C57Bl/6J) cancer susceptibility. Toxicology letters 20040401
Analysis of thresholds for carcinogenicity. Toxicology letters 20040401
Revised rat multi-organ carcinogenesis bioassay for whole-body detection of chemopreventive agents: modifying potential of S-methylcysteine. Cancer letters 20040331
Disseminated tumor cells homing into rats' liver: a new possible mechanism of HCC recurrence. World journal of gastroenterology 20040315
IFN-alpha prevents the growth of pre-neoplastic lesions and inhibits the development of hepatocellular carcinoma in the rat. Carcinogenesis 20040301
Specific differences in gene expression profile revealed by cDNA microarray analysis of glutathione S-transferase placental form (GST-P) immunohistochemically positive rat liver foci and surrounding tissue. Carcinogenesis 20040301
Inhibition of liver carcinogenesis in Wistar rats by consumption of an aqueous extract from leaves of Ardisia compressa. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040301
Preventive effect of Ganfujian granule on experimental hepatocarcinoma in rats. World journal of gastroenterology 20040301
Transgenic mice expressing hepatitis B virus X protein are more susceptible to carcinogen induced hepatocarcinogenesis. Experimental and molecular pathology 20040201
Rapid analysis of gene expression changes caused by liver carcinogens and chemopreventive agents using a newly developed three-dimensional microarray system. Cancer science 20040201
Resveratrol inhibits N-nitrosodiethylamine-induced ornithine decarboxylase and cyclooxygenase in mice. Journal of nutritional science and vitaminology 20040201
Chemically induced immunotoxicity in a medium-term multiorgan bioassay for carcinogenesis with Wistar rats. Toxicology and applied pharmacology 20040115
Characterizing the role of MDM2 in diethylnitrosamine induced acute liver damage and development of pre-neoplastic lesions. Carcinogenesis 20040101
Suppression of metastasis by nuclear factor kappaB inhibitors in an in vivo lung metastasis model of chemically induced hepatocellular carcinoma. Cancer science 20040101
Effect of cacao liquor extract on tumor marker enzymes during chemical hepatocarcinogenesis in rats. Journal of medicinal food 20040101
A liver micronucleus assay using young rats exposed to diethylnitrosamine: methodological establishment and evaluation. Cytogenetic and genome research 20040101
Liver-specific expression of the agouti gene in transgenic mice promotes liver carcinogenesis in the absence of obesity and diabetes. Molecular cancer 20040101
Protective role of Apigenin on the status of lipid peroxidation and antioxidant defense against hepatocarcinogenesis in Wistar albino rats. Phytomedicine : international journal of phytotherapy and phytopharmacology 20040101
High dietary intake of sodium selenite induces oxidative DNA damage in rat liver. Nutrition and cancer 20040101
Dietary supplementation of the citrus antioxidant auraptene inhibits N,N-diethylnitrosamine-induced rat hepatocarcinogenesis. Oncology 20040101
Antioxidant-associated chemoprevention by sodium selenite in N-nitrosodiethylamine-induced and phenobarbital-promoted hepatocarcinogenesis in rats. Cell biochemistry and function 20040101
Thresholds for the effects of 2-acetylaminofluorene in rat liver. Toxicologic pathology 20040101
The unknown nuclear protein that decreases HNF3 activity ensures species specificity of action of hepatocarcinogenic amino azo dyes. Doklady. Biochemistry and biophysics 20040101
Potential anticancer effect of red spinach (Amaranthus gangeticus) extract. Asia Pacific journal of clinical nutrition 20040101
Infiltrating CD8+ T lymphocytes, natural killer cells, and expression of IL-10 and TGF-beta1 in chemically induced neoplasms in male Wistar rats. Toxicologic pathology 20040101
Chemopreventive effect of indole-3-carbinol on induction of preneoplastic altered hepatic foci. Nutrition and cancer 20040101
Genetics of tobacco use. Tobacco induced diseases 20040101
N-nitrosodiethanolamine. Report on carcinogens : carcinogen profiles 20040101
N-Nitrosodiethylamine. Report on carcinogens : carcinogen profiles 20040101
Heterologous expression of human cytochrome P450 2E1 in HepG2 cell line. World journal of gastroenterology 20031215
Photochemistry of 1-(N,N-diethylamino)diazen-1-ium-1,2-diolate: an experimental and computational investigation. Journal of the American Chemical Society 20031203
Reduced hepatocyte proliferation is the basis of retarded liver tumor progression and liver regeneration in mice lacking N-acetylglucosaminyltransferase III. Cancer research 20031115
N-Nitrosodiethylamine mutagenicity at low concentrations. Toxicology letters 20031101
Chemoprevention of preneoplastic liver foci development by dietary mushroom Agaricus blazei Murrill in the rat. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20031101
Effect of dietary selenite on N-nitrosodiethylamine-induced and phenobarbital promoted multistage hepatocarcinogenesis in rat: reflection in some minerals. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20031101
Grape extracts suppress the formation of preneoplastic foci and activity of fatty acid synthase in rat liver. Experimental & molecular medicine 20031031
N-nitrosodiethanolamine urinary excretion in workers exposed to aqueous metalworking fluids. International archives of occupational and environmental health 20031001
Solvent polarity and hydrogen-bonding effects on the nitrogen NMR shieldings of N-nitrosamines and DFT calculations of the shieldings of C-, N-, and O-nitroso systems. Journal of magnetic resonance (San Diego, Calif. : 1997) 20031001
Effects of crude extracts of Agaricus blazei on DNA damage and on rat liver carcinogenesis induced by diethylnitrosamine. Genetics and molecular research : GMR 20030930
Chemopreventive effect of garlic powder diet in diethylnitrosamine-induced rat hepatocarcinogenesis. Life sciences 20030926
Sustained hepatic expression of FoxM1B in transgenic mice has minimal effects on hepatocellular carcinoma development but increases cell proliferation rates in preneoplastic and early neoplastic lesions. Oncogene 20030918
Diversity of selective environmental substrates for human cytochrome P450 2A6: alkoxyethers, nicotine, coumarin, N-nitrosodiethylamine, and N-nitrosobenzylmethylamine. Toxicology letters 20030915
Absence of liver tumor promoting effects of annatto extract (norbixin), a natural carotenoid food color, in a medium-term liver carcinogenesis bioassay using male F344 rats. Cancer letters 20030910
Induction of apoptosis in mouse liver adenoma and carcinoma in vivo by transforming growth factor-beta1. Journal of cancer research and clinical oncology 20030901
Development of a new method for the determination of nitrosamines by micellar electrokinetic capillary chromatography. Water research 20030901
STAT-3 activity in chemically-induced hepatocellular carcinoma. European journal of cancer (Oxford, England : 1990) 20030901
Detection by dual color fluorescence in situ hybridization of in vivo chromosome damage in rat hepatocyte nuclei. Mutagenesis 20030901
Early resistance to cell death and to onset of the mitochondrial permeability transition during hepatocarcinogenesis with 2-acetylaminofluorene. Proceedings of the National Academy of Sciences of the United States of America 20030819
Selective accumulation of ALA-induced PpIX and photodynamic effect in chemically induced hepatocellular carcinoma. British journal of cancer 20030818
Area under the curve as a dose metric for promotional responses following 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure. Toxicology and applied pharmacology 20030815
C57BR/cdJ hepatocarcinogen susceptibility genes act cell-autonomously in C57BR/cdJ<-->C57BL/6J chimeras. Cancer research 20030815
ras oncogene mutations in diethylnitrosamine-induced hepatic tumors in medaka (Oryzias latipes), a teleost fish. Mutation research 20030805
Influence of sodium selenite on glycoprotein contents in normal and N-nitrosodiethylamine initiated and phenobarbital promoted rat liver tumors. Pharmacological research 20030801
Phenobarbital at low dose exerts hormesis in rat hepatocarcinogenesis by reducing oxidative DNA damage, altering cell proliferation, apoptosis and gene expression. Carcinogenesis 20030801
TNP-470 inhibits oxidative stress, nitric oxide production and nuclear factor kappa B activation in a rat model of hepatocellular carcinoma. Free radical research 20030801
Changes in some indices of the synthesis of nitric oxide during the early stages of hepatocarcinogenesis. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20030701
Stochastic simulation of hepatic preneoplastic foci development for four chlorobenzene congeners in a medium-term bioassay. Toxicological sciences : an official journal of the Society of Toxicology 20030601
Sodium selenite modulates tumour marker indices in N-nitrosodiethylamine-initiated and phenobarbital-promoted rat liver carcinogenesis. Cell biochemistry and function 20030601
Inhibition of nuclear protein phosphatase activity in mouse hepatocytes by the cyanobacterial toxin microcystin-LR. Toxicon : official journal of the International Society on Toxinology 20030601
Prevention of dual promoting effects of pentachlorophenol, an environmental pollutant, on diethylnitrosamine-induced hepato- and cholangiocarcinogenesis in mice by green tea infusion. Carcinogenesis 20030601
Induction of apoptosis in mouse and human carcinoma cell lines by Emblica officinalis polyphenols and its effect on chemical carcinogenesis. Journal of experimental & clinical cancer research : CR 20030601
Phenotypic reversion of rat neoplastic liver nodules is under genetic control. International journal of cancer 20030520
Effect of arsenic trioxide on rat hepatocellular carcinoma and its renal cytotoxity. World journal of gastroenterology 20030515
Mice lacking a transcriptional corepressor Tob are predisposed to cancer. Genes & development 20030515
Threshold for carcinogenicity of N-nitrosodiethylamine for esophageal tumors in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20030501
Molecular profiling of hepatocellular carcinomas developing spontaneously in acyl-CoA oxidase deficient mice: comparison with liver tumors induced in wild-type mice by a peroxisome proliferator and a genotoxic carcinogen. Carcinogenesis 20030501
Spectrum of molecular changes during hepatocarcinogenesis induced by DEN and other chemicals in Fisher 344 male rats [Mechanisms of Ageing and Development 123 (2002) 1665-1680]. Mechanisms of ageing and development 20030501
[Effect of Sorbaria Sorbifolia extract on anti-oxidative activities in rats with precancerosis induced by diethylnitrosamine]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20030501
Investigating genotoxic and hematotoxic effects of N-nitrosodimethylamine, N-nitrosodiethylamine and N-nitrosodiethanolamine in the hen's egg-micronucleus test (HET-MN). Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20030401
Reduced hepatic tumor incidence in cyclin G1-deficient mice. Hepatology (Baltimore, Md.) 20030401
Inhibition of nitrosodiethylamine-induced hepatocarcinogenesis by dietary turmeric in rats. Toxicology letters 20030320
Insulin-like growth factor binding protein-1 over-expression in transgenic mice inhibits hepatic preneoplasia. Molecular carcinogenesis 20030301
Involvement of YY1 and its correlation with c-myc in NDEA induced hepatocarcinogenesis, its prevention by d-limonene. Molecular biology reports 20030301
Arsenic trioxide induces apoptosis of rat hepatocellular carcinoma cells in vivo. Journal of experimental & clinical cancer research : CR 20030301
Preliminary investigation on regulating effects of different TCM treatments on transcription of the correlated genes of liver cancer in rats. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 20030301
Suppressive effect of herbal compound 861 on chemical hepatocarcinogenesis in rats. Chinese medical journal 20030301
Chemoprevention of lung carcinogenesis by cacao liquor proanthocyanidins in a male rat multi-organ carcinogenesis model. Cancer letters 20030227
Loss of Igf2 imprinting in monoclonal mouse hepatic tumor cells is not associated with abnormal methylation patterns for the H19, Igf2, and Kvlqt1 differentially methylated regions. The Journal of biological chemistry 20030221
Sodium selenite, dietary micronutrient, prevents the lymphocyte DNA damage induced by N-nitrosodiethylamine and phenobarbital promoted experimental hepatocarcinogenesis. Journal of cellular biochemistry 20030215
Expression of IGF-II in early experimental hepatocellular carcinomas and its significance in early diagnosis. World journal of gastroenterology 20030215
Antigenotoxic, antimutagenic and ROS scavenging activities of a Rhoeo discolor ethanolic crude extract. Toxicology in vitro : an international journal published in association with BIBRA 20030201
Chemoprevention of DMBA-induced UV-B promoted, NOR-1-induced TPA promoted skin carcinogenesis, and DEN-induced phenobarbital promoted liver tumors in mice by extract of beetroot. Pharmacological research 20030201
[Preservation of mucosal specimens before processing in the alkaline single cell microgel electrophoresis assay]. HNO 20030201
Enhancing effects of mustard oil on preneoplastic hepatic foci development in Wistar rats. Human & experimental toxicology 20030201
Agaricus blazei (Himematsutake) does not alter the development of rat diethylnitrosamine-initiated hepatic preneoplastic foci. Cancer science 20030201
Relationship between the imaging features and pathologic alteration in hepatoma of rats. World journal of gastroenterology 20030115
Challenging dogma: thresholds for genotoxic carcinogens? The case of vinyl acetate. Annual review of pharmacology and toxicology 20030101
Suppressive effect of Astragalus membranaceus Bunge on chemical hepatocarcinogenesis in rats. Cancer chemotherapy and pharmacology 20030101
Growth-inhibitory effects of the chemopreventive agent indole-3-carbinol are increased in combination with the polyamine putrescine in the SW480 colon tumour cell line. BMC cancer 20030101
Polychlorinated biphenyls as initiators in liver carcinogenesis: resistant hepatocyte model. Toxicology and applied pharmacology 20030101
Pentachlorophenol (but not phenobarbital) promotes intrahepatic biliary cysts induced by diethylnitrosamine to cholangio cystic neoplasms in B6C3F1 mice possibly due to oxidative stress. Toxicologic pathology 20030101
Prevalidation of a rat liver foci bioassay (RLFB) based on results from 1600 rats: a study report. Toxicologic pathology 20030101
Value of GST-P positive preneoplastic hepatic foci in dose-response studies of hepatocarcinogenesis: evidence for practical thresholds with both genotoxic and nongenotoxic carcinogens. A review of recent work. Toxicologic pathology 20030101
Role of connexin32 and beta-catenin in tumor promotion in mouse liver. Toxicologic pathology 20030101
Different effects of the liver mitogens triiodo-thyronine and ciprofibrate on the development of rat hepatocellular carcinoma. Toxicologic pathology 20030101
Tumor promotion by metanil yellow and malachite green during rat hepatocarcinogenesis is associated with dysregulated expression of cell cycle regulatory proteins. Teratogenesis, carcinogenesis, and mutagenesis 20030101
A medium-term rat liver bioassay for rapid in vivo detection of carcinogenic potential of chemicals. Cancer science 20030101
Suppression of altered hepatic foci development by curcumin in wistar rats. Nutrition and cancer 20030101
Preventive effect of fermented brown rice and rice bran on diethylnitrosoamine and phenobarbital-induced hepatocarcinogenesis in male F344 rats. Oncology reports 20030101
Stabilization of membrane bound enzyme profiles by sodium selenite in N-nitrosodiethylamine induced and phenobarbital promoted hepatocarcinogenesis in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20030101
S-allylcysteine inhibits circulatory lipid peroxidation and promotes antioxidants in N-nitrosodiethylamine-induced carcinogenesis. Polish journal of pharmacology 20030101
The copper-chelating agent, trientine, attenuates liver enzyme-altered preneoplastic lesions in rats by angiogenesis suppression. Oncology reports 20030101
[Liver radiosensitivity to gamma radiation in mice poisoned with N-nitrosodiethylamine]. Roczniki Panstwowego Zakladu Higieny 20030101
Effects of dietary taurine supplementation on hepatic morphological changes of rats in diethylnitrosamine-induced hepatocarcinogenesis. Advances in experimental medicine and biology 20030101
[Tumor-associated hetero-organic antigens as markers of deranged cell differentiation and malignancy]. Voprosy onkologii 20030101
[N-nitrosodiethylamine-induced changes in the liver of syrian hamster with superinvasive opistorchiasis]. Voprosy onkologii 20030101
Diethylnitrosamine may induce esophageal dysplasia after local intramural administration. Roczniki Akademii Medycznej w Bialymstoku (1995) 20030101
Peroxisomal enzymes and 8-hydroxydeoxyguanosine in rat liver treated with perfluorooctanoic acid. Disease markers 20030101
Chemopreventive effects of melatonin on diethylnitrosamine and phenobarbital-induced hepatocarcinogenesis in male F344 rats. Nutrition and cancer 20030101
Biological consequences of overexpressing or eliminating N-acetylglucosaminyltransferase-TIII in the mouse. Biochimica et biophysica acta 20021219
K vitamins, PTP antagonism, and cell growth arrest. Journal of cellular physiology 20021201
Dietary influence of selenium on the incidence of N-nitrosodiethylamine-induced hepatoma with reference to drug and glutathione metabolizing enzymes. Cell biochemistry and function 20021201
Cellular origin of hepatocellular carcinomas. Seminars in cell & developmental biology 20021201
[Superparamagnetic iron oxide-enhanced magnetic resonance imaging of hepatocellular carcinoma in rats]. Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20021201
Effects of tea on preneoplastic lesions and cell cycle regulators in rat liver. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20021201
Intake of volatile N-nitrosamines and their ability to exogenously synthesize in the diet of inhabitants from high-risk area of esophageal cancer in southern China. Biomedical and environmental sciences : BES 20021201
Anticarcinogenic effect and modification of cytochrome P450 2E1 by dietary garlic powder in diethylnitrosamine-initiated rat hepatocarcinogenesis. Journal of biochemistry and molecular biology 20021130
Dietary exposure and urinary excretion of total N-nitroso compounds, nitrosamino acids and volatile nitrosamine in inhabitants of high- and low-risk areas for esophageal cancer in southern China. International journal of cancer 20021120
High vascular endothelial growth factor (VEGF) expression in chemically-induced hepatic microcancers in mice. Journal of hepatology 20021101
Influence of aqueous extract of Agaricus blazei on rat liver toxicity induced by different doses of diethylnitrosamine. Journal of ethnopharmacology 20021101
Influences of a dietary fatty acid composition on the emergence of glutathione S-transferase-P (GST-P) positive foci in the liver of carcinogen-treated rats. Prostaglandins, leukotrienes, and essential fatty acids 20021101
Spectrum of molecular changes during hepatocarcinogenesis induced by DEN and other chemicals in Fischer 344 male rats. Mechanisms of ageing and development 20021101
Changes in hepatic enzyme activities in transgenic mice carrying human prototype c-Ha-ras gene treated with diethylnitrosamine. The Journal of veterinary medical science 20021101
N-ethyl-N-hydroxyethylnitrosamine (EHEN)-induced renal and hepatocarcinogenesis in the tumor suppressor Tsc2 transgenic rat. Cancer letters 20021028
Overexpression of glutamine synthetase is associated with beta-catenin-mutations in mouse liver tumors during promotion of hepatocarcinogenesis by phenobarbital. Cancer research 20021015
In ovo carcinogenicity assay (IOCA): evaluation of mannitol, caprolactam and nitrosoproline. Archives of toxicology 20021001
Dynamic changes of matrix metalloproteinases in rat liver during the development of diethylnitrosamine-induced hepatocarcinoma. Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20021001
Lack of a dose-response relationship for carcinogenicity in the rat liver with low doses of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline or N-nitrosodiethylamine. Japanese journal of cancer research : Gann 20021001
Suppression of lung metastasis by aspirin but not indomethacin in an in vivo model of chemically induced hepatocellular carcinoma. Japanese journal of cancer research : Gann 20021001
Decomposition of N-nitrosamines, and concomitant release of nitric oxide by Fenton reagent under physiological conditions. Mutation research 20020926
Inhibitory effects of lemon grass (Cymbopogon citratus, Stapf) extract on the early phase of hepatocarcinogenesis after initiation with diethylnitrosamine in male Fischer 344 rats. Cancer letters 20020908
1alpha,25-Dihydroxyvitamin D(3) inhibits rat liver ultrastructural changes and the development of gamma-glutamyltranspeptidase-positive foci in diethylnitrosamine-initiated and streptozotocin-induced diabetes-promoted hepatocarcinogenesis. Cell biochemistry and function 20020901
Demonstration of direct lineage between hepatocytes and hepatocellular carcinoma in diethylnitrosamine-treated rats. Hepatology (Baltimore, Md.) 20020901
Follistatin overexpression in rodent liver tumors: a possible mechanism to overcome activin growth control. Molecular carcinogenesis 20020901
Brain stem GABA receptor functional regulation during rat liver cell proliferation. Neurochemical research 20020901
Impact of hypercholesterolemia on in vitro toxicity of N-nitrosodiethylamine: effect on lipidperoxidation of blood and tissue. Indian journal of experimental biology 20020901
Promotion of altered hepatic foci by 2,3,7,8-tetrachlorodibenzo-p-dioxin and 17beta-estradiol in male Sprague-Dawley rats. Toxicological sciences : an official journal of the Society of Toxicology 20020801
Cytotoxicity of fumonisin B1, diethylnitrosamine, and catechol on the SNO esophageal cancer cell line. Environmental health perspectives 20020801
Chromosome mapping of multiple loci affecting the genetic predisposition to rat liver carcinogenesis. Cancer research 20020801
Role of human cytochrome P450 (CYP) in the metabolic activation of nitrosamine derivatives: application of genetically engineered Salmonella expressing human CYP. Drug metabolism reviews 20020801
[Influence of spleen on cell cycle and expression of proliferating cell nuclear antigen of the liver during diethylnitrosamine-induced rat hepatocarcinogenesis]. Zhonghua wai ke za zhi [Chinese journal of surgery] 20020801
A glycomic approach to hepatic tumors in N-acetylglucosaminyltransferase III (GnT-III) transgenic mice induced by diethylnitrosamine (DEN): identification of haptoglobin as a target molecule of GnT-III. Free radical research 20020801
Promoting effects of monomethylarsonic acid, dimethylarsinic acid and trimethylarsine oxide on induction of rat liver preneoplastic glutathione S-transferase placental form positive foci: a possible reactive oxygen species mechanism. International journal of cancer 20020710
Inhibition of renin-angiotensin system attenuates liver enzyme-altered preneoplastic lesions and fibrosis development in rats. Journal of hepatology 20020701
Marked inhibition of testosterone biosynthesis by the hepatotoxin nodularin due to apoptosis of Leydig cells. Molecular carcinogenesis 20020701
Anomalous elevation of glutathione S-transferase P-form (GST-P) in the elementary process of epigenetic initiation of chemical hepatocarcinogenesis in rats. Carcinogenesis 20020701
Chemoprevention of hepatocarcinogenesis: S-adenosyl-L-methionine. Alcohol (Fayetteville, N.Y.) 20020701
[The expression of bcl-2 and bax genes during microcystin induced liver tumorigenesis]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20020701
Genotoxic and anti-genotoxic properties of Calendula officinalis extracts in rat liver cell cultures treated with diethylnitrosamine. Toxicology in vitro : an international journal published in association with BIBRA 20020601
Cell cycle deregulation in liver lesions of rats with and without genetic predisposition to hepatocarcinogenesis. Hepatology (Baltimore, Md.) 20020601
Down-regulation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)-induced CYP1A2 expression is associated with bovine lactoferrin inhibition of MeIQx-induced liver and colon carcinogenesis in rats. Japanese journal of cancer research : Gann 20020601
Molecular profiling of genes up-regulated during promotion by phenobarbital treatment in a medium-term rat liver bioassay. Carcinogenesis 20020601
Enhanced GABA(B) receptor in neoplastic rat liver: induction of DNA synthesis by baclofen in hepatocyte cultures. Journal of biochemistry, molecular biology, and biophysics : JBMBB : the official journal of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) 20020601
Caffeine, quercetin and alizarin stimulate the exhalation of metabolic products of [14C]-N-nitrosodiethylamine in mice. Indian journal of experimental biology 20020601
Down-regulation of von Hippel-Lindau protein in N-nitroso compound-induced rat non-clear cell renal tumors. Cancer letters 20020508
Distinctive gene expression of receptor-type tyrosine kinase families during rat hepatocarcinogenesis. International journal of molecular medicine 20020501
Effect of ethanol treatment on metabolic activation and detoxification of esophagus carcinogenic N-nitrosamines in rat liver. Mutagenesis 20020501
Hypoxia-induced VEGF and collagen I expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosis. Hepatology (Baltimore, Md.) 20020501
Effects of Sho-Saiko-to on hepatocarcinogenesis and 8-hydroxy-2'-deoxyguanosine formation. Hepatology (Baltimore, Md.) 20020501
Bcl-2 expression inhibits liver carcinogenesis and delays the development of proliferating foci. The American journal of pathology 20020501
Morphology and morphometric investigation of hepatocellular preneoplastic lesions and neoplasms in connexin32-deficient mice. Carcinogenesis 20020501
Reduction of hepatocarcinogenesis by ursodeoxycholic acid in rats. Carcinogenesis 20020501
[Basic research on lung cancer]. Nihon rinsho. Japanese journal of clinical medicine 20020501
Alterations of the Fhit gene in hepatocellular carcinomas induced by N-nitrosodiethylamine in rats. Molecular carcinogenesis 20020501
The in vivo apoptotic effect of interferon alfa-2b on rat preneoplastic liver involves Bax protein. Hepatology (Baltimore, Md.) 20020401
Effects of N-acetylcysteine in an esophageal carcinogenesis model in rats treated with diethylnitrosamine and diethyldithiocarbamate. International journal of cancer 20020401
Microsome-mediated oxidation of N-nitrosodiethanolamine (NDELA), a bident carcinogen. Chemical research in toxicology 20020401
DNA adducts from N-nitrosodiethanolamine and related beta-oxidized nitrosamines in vivo: (32)P-postlabeling methods for glyoxal- and O(6)-hydroxyethyldeoxyguanosine adducts. Chemical research in toxicology 20020401
CYP2A6/2A7 and CYP2E1 expression in human oesophageal mucosa: regional and inter-individual variation in expression and relevance to nitrosamine metabolism. Carcinogenesis 20020401
Role of mouse spleen cell HMG proteins and their poly-ADP-ribosylation in betelnut induced carcinogenesis. Indian journal of biochemistry & biophysics 20020401
Further phenotypic characterization of pso mutants of Saccharomyces cerevisiae with respect to DNA repair and response to oxidative stress. Genetics and molecular research : GMR 20020331
Regulation of cell proliferation, apoptosis, and transcription factor activities during the promotion of liver carcinogenesis by polychlorinated biphenyls. Toxicology and applied pharmacology 20020315
Hepatocyte growth factor promotes hepatocarcinogenesis through c-Met autocrine activation and enhanced angiogenesis in transgenic mice treated with diethylnitrosamine. Oncogene 20020314
Nonadditive hepatic tumor promoting effects by a mixture of two structurally different polychlorinated biphenyls in female rat livers. Toxicological sciences : an official journal of the Society of Toxicology 20020301
Nrf2 transactivator-independent GSTP1-1 expression in 'GSTP1-1 positive' single cells inducible in female mouse liver by DEN: a preneoplastic character of possible initiated cells. Carcinogenesis 20020301
[Dynamic study on expression of gelatinase A and its natural inhibitor during invasion and metastasis of induced lung cancer in Wistar rats]. Zhonghua zhong liu za zhi [Chinese journal of oncology] 20020301
Chemopreventive effect of orange oil on the development of hepatic preneoplastic lesions induced by N-nitrosodiethylamine in rats: an ultrastructural study. Indian journal of experimental biology 20020301
Anticarcinogenic effect of black tea on pulmonary tumors in Swiss albino mice. Cancer letters 20020225
Summation of initiation activities in the liver after partial hepatectomy. Cancer letters 20020208
Fast microwave-assisted dansylation of N-nitrosamines. Analysis by high-performance liquid chromatography with fluorescence detection. Journal of chromatography. A 20020208
Expression of P-glycoprotein in rat hepatocarcinogenesis by diethylnitrosamine and the modulation by anticancer drugs. Hepatology research : the official journal of the Japan Society of Hepatology 20020201
Hepatocyte growth factor and c-Met inhibition by hepatic cell hypoxia: a potential mechanism for liver regeneration failure in experimental cirrhosis. The American journal of pathology 20020201
Diethylnitrosamine induces long-lasting re-expression of insulin-like growth factor II during early stages of liver carcinogenesis in mice. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20020201
Effects of fasting and intermittent fasting on rat hepatocarcinogenesis induced by diethylnitrosamine. Teratogenesis, carcinogenesis, and mutagenesis 20020101
Quantitation of the cancer process in C57BL/6J, B6C3F1 and C3H/HeJ mice. Toxicologic pathology 20020101
Systemic administration of liposome-encapsulated OK-432 prolongs the survival of rats with hepatocellular carcinoma through the induction of IFN-gamma-producing hepatic lymphocytes. Journal of gastroenterology and hepatology 20020101
Probucol and liver efficiency during chemically-induced hepatocarcinogenesis. Anticancer research 20020101
Lack of modification of rat hepatocarcinogenesis by fernane-type triterpenoids, isolated from a Euphorbia genus. Teratogenesis, carcinogenesis, and mutagenesis 20020101
Overexpression of cyclin D1 is associated with the decondensation of chromatin during den-induced sequential hepatocarcinogenesis. Cell biology international 20020101
[Content of N-nitrosamines in smoked fish and canned food]. Gigiena i sanitariia 20020101
Administration of diethylnitrosamine in the immediate postnatal period coupled with exposure to a choline deficient diet accelerates hepatocarcinogenesis in the rat. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20020101
Experimental esophageal carcinogenesis: technical standardization and results. Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20020101
[Changes in some parameters of nitric oxide synthesis in the early periods of development of hepatocarcinogenesis]. Likars'ka sprava 20020101
[Studies on extracellular matrices in rat hepatocarcinogenesis induced by diethylnitrosamine]. Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao 20020101
[Radioprotective and antineoplastic activity of polyene antibiotics combined with dimethyl sulfoxide]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20020101
Effect of A-L tonic capsule on DNA content in rat experimental hepatocarcinogenesis. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20020101
In vivo changes in the intestinal lipid peroxidation and the crypt response to whole-body gamma irradiation in diethylnitrosamine-treated mice. Roczniki Panstwowego Zakladu Higieny 20020101
Menhaden oil inhibited gamma-glutamyltransferase-positive altered hepatic foci in female Sprague-Dawley rats. Nutrition and cancer 20020101
N-Nitrosodiethanolamine. Report on carcinogens : carcinogen profiles 20020101
N-Nitrosodiethylamine. Report on carcinogens : carcinogen profiles 20020101
Detection of DNA adducts using a quantitative long PCR technique and the fluorogenic 5' nuclease assay (TaqMan). Mutation research 20011212
Cytochrome b(5) coexpression increases the CYP2E1-dependent mutagenicity of dialkylnitrosamines in methyltransferase-deficient strains of Salmonella typhimurium. Mutation research 20011212
Chemopreventive efficacy of selenium against N-nitrosodiethylamine-induced hepatoma in albino rats. Cell biochemistry and function 20011201
Anticarcinogenic effect of red ginseng on the development of liver cancer induced by diethylnitrosamine in rats. Journal of Korean medical science 20011201
Decreased expression of Bcl-x protein during hepatocarcinogenesis induced exogenously and endogenously in rats. Japanese journal of cancer research : Gann 20011201
Reduced ATM kinase activity and an attenuated p53 response to DNA damage in carcinogen-induced preneoplastic hepatic lesions in the rat. Carcinogenesis 20011201
Release of nitric oxide together with carbon-centered radicals from N-nitrosamines by ultraviolet light irradiation. Free radical research 20011201
[Studies on liver cancer induced by non-necrotizing dose of diethylnitrosamine in rats]. Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao 20011201
Selective pressure during tumor promotion by phenobarbital leads to clonal outgrowth of beta-catenin-mutated mouse liver tumors. Oncogene 20011122
Role of human cytochrome P450 (CYP) in the metabolic activation of N-alkylnitrosamines: application of genetically engineered Salmonella typhimurium YG7108 expressing each form of CYP together with human NADPH-cytochrome P450 reductase. Mutation research 20011101
The importance of distinct metabolites of N-nitrosodiethylamine for its in vivo mutagenic specificity. Mutation research 20011101
The little mutation suppresses DEN-induced hepatocarcinogenesis in mice and abrogates genetic and hormonal modulation of susceptibility. Carcinogenesis 20011101
Rat oesophageal cytochrome P450 (CYP) monooxygenase system: comparison to the liver and relevance in N-nitrosodiethylamine carcinogenesis. Carcinogenesis 20011101
Organotropic chemopreventive effects of n-3 unsaturated fatty acids in a rat multi-organ carcinogenesis model. Japanese journal of cancer research : Gann 20011101
The polycyclic musk 7-acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphthaline lacks liver tumor initiating and promoting activity in rats exposed to human-relevant doses. Archives of toxicology 20011101
Inheritance of resistance to promotion of preneoplastic liver lesions in Copenhagen rats. Experimental biology and medicine (Maywood, N.J.) 20011001
Butylhydroxytoluene (BHT) increases susceptibility of transgenic rasH2 mice to lung carcinogenesis. Journal of cancer research and clinical oncology 20011001
Cell type-specific induction of O6-alkylguanine-DNA alkyltransferase mRNA expression in rat liver during regeneration, inflammation and preneoplasia. Journal of cancer research and clinical oncology 20011001
Efficient and cancer-selective gene transfer to hepatocellular carcinoma in a rat using adenovirus vector with iodized oil esters. Cancer gene therapy 20011001
Immunohistochemical characterization of hepatoblastomas in B6C3F1 mice treated with diethylnitrosamine and sodium phenobarbital. The Journal of veterinary medical science 20011001
[Genetic control of hepatocarcinogenesis in mice]. Nihon rinsho. Japanese journal of clinical medicine 20011001
Assessment of chronic toxicity and carcinogenicity in an accelerated cancer bioassay in rats of moxifloxacin, a quinolone antibiotic. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20011001
Strain variation in renal carcinogenesis by N-ethyl-N-hydroxyethylnitrosamine in F1 (Wistar-Fischer) rats. Cancer letters 20010920
Heterozygous mice for the transforming growth factor-beta type II receptor gene have increased susceptibility to hepatocellular carcinogenesis. Cancer research 20010915
Matrix metalloproteinases-2 and 9 do not play a role in the growth of preneoplastic liver lesions in F344 rats. Experimental biology and medicine (Maywood, N.J.) 20010901
Resistance of primary cultured mouse hepatic tumor cells to cellular senescence despite expression of p16(Ink4a), p19(Arf), p53, and p21(Waf1/Cip1). Molecular carcinogenesis 20010901
Diethylnitrosamine causes pituitary damage, disturbs hormone levels, and reduces sexual dimorphism of certain liver functions in the rat. Environmental health perspectives 20010901
Effect of alpha-tocopherol on hepatocarcinogenesis in transforming growth factor-alpha (TGF-alpha) transgenic mice treated with diethylnitrosamine. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20010901
Effect of metanil yellow and malachite green on DNA synthesis in N-nitrosodiethylamine induced preneoplastic rat livers. Indian journal of experimental biology 20010901
Hepatocellular expression of a dominant-negative mutant TGF-beta type II receptor accelerates chemically induced hepatocarcinogenesis. Oncogene 20010816
Clustering of hepatotoxins based on mechanism of toxicity using gene expression profiles. Toxicology and applied pharmacology 20010815
Low gastric toxicity of nitric oxide-releasing aspirin, NCX-4016, in rats with cirrhosis and arthritis. Digestive diseases and sciences 20010801
Role of Atp7b gene in spontaneous and N-diethylnitrosamine-induced carcinogenesis in a new congenic strain, WKAH.C-Atp7b rats. Japanese journal of cancer research : Gann 20010801
Reaction of fumonisin with glucose prevents promotion of hepatocarcinogenesis in female F344/N rats while maintaining normal hepatic sphinganine/sphingosine ratios. Journal of agricultural and food chemistry 20010801
Proteome analysis of rat hepatomas: carcinogen-dependent tumor-associated protein variants. Electrophoresis 20010801
Preventive effect of FK143, a 5alpha-reductase inhibitor, on chemical hepatocarcinogenesis in rats. Clinical cancer research : an official journal of the American Association for Cancer Research 20010701
Induction of hepatic 8-oxo-deoxyguanosine adducts by 2,3,7,8-tetrachlorodibenzo-p-dioxin in Sprague-Dawley rats is female-specific and estrogen-dependent. Chemical research in toxicology 20010701
Cancare-a herbal formulation inhibits chemically induced tumours in experimental animals. Indian journal of experimental biology 20010701
Importance of DNA repair in carcinogenesis: evidence from transgenic and gene targeting studies. Mutation research 20010602
Involvement of gap junctions in tumor suppression: analysis of genetically-manipulated mice. Mutation research 20010602
Chemopreventive effects of scordinin on diethylnitrosamine and phenobarbital-induced hepatocarcinogenesis in male F344 rats. Japanese journal of cancer research : Gann 20010601
Regulation of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced tumor promotion by 17 beta-estradiol in female Sprague--Dawley rats. Toxicology and applied pharmacology 20010515
Expression profiling and identification of novel genes in hepatocellular carcinomas. Oncogene 20010510
DNA damage induced by red food dyes orally administered to pregnant and male mice. Toxicological sciences : an official journal of the Society of Toxicology 20010501
Inhibition of chemical carcinogenesis by berberine in rats and mice. The Journal of pharmacy and pharmacology 20010501
Mutagen sensitivity of nasopharyngeal cancer patients. Mutation research 20010405
Overexpressed growth hormone (GH) synergistically promotes carcinogen-initiated liver tumour growth by promoting cellular proliferation in emerging hepatocellular neoplasms in female and male GH-transgenic mice. Liver 20010401
Genotoxic effects of N-nitrosodicyclohexylamine in isolated human lymphocytes. Archives of toxicology 20010401
Study on mechanism of multistep hepatotumorigenesis in rat: development of hepatotumorigenesis. Journal of veterinary science 20010401
Microarray analysis of hepatotoxins in vitro reveals a correlation between gene expression profiles and mechanisms of toxicity. Toxicology letters 20010331
1 alpha,25-Dihydroxyvitamin D(3) inhibits rat liver ultrastructural changes in diethylnitrosamine-initiated and phenobarbital promoted rat hepatocarcinogenesis. Journal of cellular biochemistry 20010326
Frequency of CYP2A6 gene deletion and its relation to risk of lung and esophageal cancer in the Chinese population. International journal of cancer 20010320
Establishment of rat hepatocellular carcinoma cell lines with differing metastatic potential in nude mice. International journal of cancer 20010315
Gas chromatographic-mass spectrometric determination of hydrophilic compounds in environmental water by solid-phase extraction with activated carbon fiber felt. Journal of chromatography. A 20010309
Effect of selenium on N-nitrosodiethylamine-induced multistage hepatocarcinogenesis with reference to lipid peroxidation and enzymic antioxidants. Cell biochemistry and function 20010301
Sex hormone dependency of diethylnitrosamine-induced liver tumors in mice and chemoprevention by leuprorelin. Japanese journal of cancer research : Gann 20010301
A clonal growth model: time-course simulations of liver foci growth following penta- or hexachlorobenzene treatment in a medium-term bioassay. Cancer research 20010301
Activation of beta-catenin during hepatocarcinogenesis in transgenic mouse models: relationship to phenotype and tumor grade. Cancer research 20010301
Sequential changes in hepatocarcinogenesis induced by diethylnitrosamine plus thioacetamide in Fischer 344 rats: induction of gankyrin expression in liver fibrosis, pRB degradation in cirrhosis, and methylation of p16(INK4A) exon 1 in hepatocellular carcinoma. Molecular carcinogenesis 20010301
Chemically induced carcinogenesis: a comparison of 1-methyl-1-nitrosourea, 7,12-dimethylbenzanthracene,diethylnitroso-amine and azoxymethan models (minireview). Endocrine regulations 20010301
Bioassay of mannitol and caprolactam and assessment of response to diethylnitrosamine in heterozygous p53-deficient (+/-) and wild type (+/+) mice. Archives of toxicology 20010301
Liposome encapsulated tumor-associated antigens elicited humoral and cellular immune responses in mice bearing tumor. Indian journal of experimental biology 20010301
Presence of a no-observed effect level for enhancing effects of development of the alpha-isomer of benzene hexachloride (alpha-BHC) on diethylnitrosamine-initiated hepatic foci in rats. Cancer letters 20010226
Establishment and characterization of three new rat renal cell carcinoma cell lines from N-ethyl-N-hydroxyethylnitrosamine-induced basophilic cell tumors. Pathology international 20010201
Long-term dehydroepiandrosterone and 16alpha-fluoro-5-androsten-17-one administration enhances DNA synthesis and induces expression of c-fos and c-Ha-ras in a selected population of preneoplastic lesions in liver of diethylnitrosamine-initiated rats. Carcinogenesis 20010201
Resistance of Copenhagen rats to hepatocarcinogenesis does not involve T-cell immunity. Carcinogenesis 20010201
Epoprostenol sodium, a prostaglandin I2, lacks tumor promoting effects in a medium-term liver carcinogenesis bioassay in rats. Cancer letters 20010126
Mdr1b facilitates p53-mediated cell death and p53 is required for Mdr1b upregulation in vivo. Oncogene 20010118
Gene therapy of orthotopic hepatocellular carcinoma in rats using adenovirus coding for interleukin 12. Hepatology (Baltimore, Md.) 20010101
Selective left-lobe atrophy by nodularin treatment accompanied by reduced protein phosphatase 1/2A and increased peroxisome proliferation in rat liver. International journal of cancer 20010101
Alterations of the transforming growth factor-beta signaling pathway in hepatocellular carcinomas induced endogenously and exogenously in rats. Japanese journal of cancer research : Gann 20010101
Hypothalamic GABA receptor functional regulation and liver cell proliferation. Molecular and cellular biochemistry 20010101
Anti-tumor promoting activity of Asteracantha longifolia against experimental hepatocarcinogenesis in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20010101
[DNA repair if mucous membrane cells and lymphocytes with the comet assay]. Laryngo- rhino- otologie 20010101
Tumor-specific action of sodium 5,6-benzylidene-L-ascorbate in N-nitrosodiethylamine-administered mouse model. Anticancer research 20010101
Possible prevention by abieslactone of development of diethylnitrosamine-initiated GST-P positive foci in the rat liver. Teratogenesis, carcinogenesis, and mutagenesis 20010101
1alpha, 25-Dihydroxyvitamin D3 suppresses the effect of streptozotocin-induced diabetes during chemical rat liver carcinogenesis. Cell biology international 20010101
Enhancement of N-nitrosodiethylamine-initiated hepatocarcinogenesis by phentoin in male F344/NCr rats at a dose causing maximal induction of CYP2B. International journal of toxicology 20010101
Genotoxicity of nitroso compounds and sodium dichromate in a model combining organ cultures of human nasal epithelia and the comet assay. ORL; journal for oto-rhino-laryngology and its related specialties 20010101
Specific genomic alterations in rat renal cell carcinomas induced by N-ethyl-N-hydroxyethylnitrosamine. Toxicologic pathology 20010101
An in vivo method for using 5-bromo-2'-deoxyuridine (BrdU) as a marker of chemically-induced hepatocellular proliferation in the Japanese medaka (Oryzias latipes). Toxicologic pathology 20010101
Nuclear Ras: unexpected subcellular distribution of oncogenic forms. Journal of cellular biochemistry. Supplement 20010101
Nitric oxide synthase inhibitors reduced lipid peroxidation in N-nitrosodiethylamine-treated rats. Roczniki Panstwowego Zakladu Higieny 20010101
Greater expression of transforming growth factor alpha and proliferating cell nuclear antigen staining in mouse hepatoblastomas than hepatocellular carcinomas induced by a diethylnitrosamine-sodium phenobarbital regimen. Toxicologic pathology 20010101
Determination of N-nitrosodimethylamine in environmental aqueous samples by isotope-dilution GC/MS-SIM. Journal of AOAC International 20010101
Effects of griseofulvin in medium-term liver carcinogenesis assay and peripheral blood micronucleus test in rat. Teratogenesis, carcinogenesis, and mutagenesis 20010101
Vitamin A and all-trans and 9-cis retinoic acids inhibit cell proliferation during the progression phase of hepatocarcinogenesis in Wistar rats. Nutrition and cancer 20010101
Predicting the mutagenicity of tobacco-related N-nitrosamines in humans using 11 strains of Salmonella typhimurium YG7108, each coexpressing a form of human cytochrome P450 along with NADPH-cytochrome P450 reductase. Environmental and molecular mutagenesis 20010101
Evaluation of genotoxic activity of maleic hydrazide, ethyl methane sulfonate, and N-nitroso diethylamine in Tradescantia. Salud publica de Mexico 20010101
Dose-dependent promotion by phenylethyl isothiocyanate, a known chemopreventer, of two-stage rat urinary bladder and liver carcinogenesis. Nutrition and cancer 20010101
Comparison between the Effect of Soybean and Goat's Milk on Tumor-Marker Enzyme Activities During Hepatocarcinogenesis in Rats. The Malaysian journal of medical sciences : MJMS 20010101
Liver tumor-promoting activity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in TCDD-sensitive and TCDD-resistant rat strains. Cancer research 20001215
Mutagenicity of nitrosamines in methyltransferase-deficient strains of Salmonella typhimurium coexpressing human cytochrome P450 2E1 and reductase. Mutation research 20001106
Loss of nuclear p53 protein in preneoplastic rat hepatocytes is accompanied by Mdm2 and Bcl-2 overexpression and by defective response to DNA damage in vivo. Hepatology (Baltimore, Md.) 20001001
Ovarian tumors in rats induced by chronic 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment. Cancer research 20001001
Lack of phenobarbital-mediated promotion of hepatocarcinogenesis in connexin32-null mice. Cancer research 20000915
Overexpression of G1/S cyclins and PCNA and their relationship to tyrosine phosphorylation and dephosphorylation during tumor promotion by metanil yellow and malachite green. Toxicology letters 20000727
[Effect of tea polyphenols and tea pigments on inducing the activity of phase II detoxicating enzymes and on the chemoprevention of liver precancerous lesions]. Wei sheng yan jiu = Journal of hygiene research 20000530
Absence of p16, p21 and p53 gene alterations in hepatocellular carcinomas induced by N-nitrosodiethylamine or a choline-deficient L-amino acid-defined diet in rats. Cancer letters 20000428
Evaluation of flutamide genotoxicity in rats and in primary human hepatocytes. Pharmacology & toxicology 20000301
Bile acid secretion during rat liver carcinogenesis. Life sciences 20000211
Comparative hepatocarcinogenicity of hexachlorobenzene, pentachlorobenzene, 1,2,4,5-tetrachlorobenzene, and 1,4-dichlorobenzene: application of a medium-term liver focus bioassay and molecular and cellular indices. Toxicological sciences : an official journal of the Society of Toxicology 20000201
Diet restriction increases ubiquinone contents and inhibits progression of hepatocellular carcinoma in the rat. Scandinavian journal of gastroenterology 20000101
Lack of p53 protein expression in preneoplastic rat hepatocytes in vitro after exposure to N-acetoxy-acetylaminofluorene, X-rays or a proteasome inhibitor. European journal of cancer (Oxford, England : 1990) 20000101
Further evidence for chemopreventive potential of beta-carotene against experimental carcinogenesis: diethylnitrosamine-initiated and phenobarbital-promoted hepatocarcinogenesis is prevented more effectively by beta-carotene than by retinoic acid. Nutrition and cancer 20000101
Induction of lung lesions in female rats following chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicologic pathology 20000101
The relationship between decrease in Cx32 and induction of P450 isozymes in the early phase of clofibrate hepatocarcinogenesis in the rat. Archives of toxicology 19990901
Different frequencies and patterns of beta-catenin mutations in hepatocellular carcinomas induced by N-nitrosodiethylamine and a choline-deficient L-amino acid-defined diet in rats. Cancer research 19990815
Dose-dependent induction of carcinomas and glutathione S-transferase placental form negative eosinophilic foci in the rat liver by di(2-ethylhexyl)phthalate after diethylnitrosamine initiation. The Journal of toxicological sciences 19990801
Promoting activity of the herbicide dicamba (2-methoxy-3, 6-dichlorobenzoic acid) in two stage hepatocarcinogenesis. International journal of oncology 19990101
Natural killer activity in a medium-term multi-organ bioassay for carcinogenesis. Japanese journal of cancer research : Gann 19990101
d-limonene chemoprevention of hepatocarcinogenesis in AKR mice: inhibition of c-jun and c-myc. Oncology reports 19990101
Inhibitory effect of Trianthema portulacastrum L. diethylnitroso-amine-induced phenobarbital promoted hepatocarcinogenesis. Neoplasma 19990101
Presence of a threshold for promoting effects of phenobarbital on diethylnitrosamine-induced hepatic foci in the rat. Carcinogenesis 19980801
Ferric nitrilotriacetate promotes N-diethylnitrosamine-induced renal tumorigenesis in the rat: implications for the involvement of oxidative stress. Carcinogenesis 19980601
Studies of initiation and promotion of carcinogenesis by N-nitroso compounds. Cancer letters 19980130
Effects of the lignan, arctiin, on 17-beta ethinyl estradiol promotion of preneoplastic liver cell foci development in rats. Anticancer research 19980101
Tea and tea polyphenols inhibit cell hyperproliferation, lung tumorigenesis, and tumor progression. Experimental lung research 19980101
The tetratricopeptide repeat containing Tg737 gene is a liver neoplasia tumor suppressor gene. Oncogene 19971009
p53 protein expression by hepatocarcinogens in the rat liver and its potential role in mitoinhibition of normal hepatocytes as a mechanism of hepatic tumour promotion. Carcinogenesis 19970501
Enhancing effects of phenobarbital and 3-methylcholanthrene on GST-P-positive liver cell foci development in a new medium-term rat liver bioassay using D-galactosamine. Journal of toxicology and environmental health 19970411
Effects of n-tritriacontane-16,18-dione, curcumin, chlorphyllin, dihydroguaiaretic acid, tannic acid and phytic acid on the initiation stage in a rat multi-organ carcinogenesis model. Cancer letters 19970226
Highly metastatic hepatocellular carcinomas induced in male F344 rats treated with N-nitrosomorpholine in combination with other hepatocarcinogens show a high incidence of p53 gene mutations along with altered mRNA expression of tumor-related genes. Cancer letters 19970115
Quantitative relationship between transforming growth factor-alpha and hepatic focal phenotype and progression in female mouse liver. Toxicologic pathology 19970101
Induction of hsp 70 in HepG2 cells in response to hepatotoxicants. Toxicology and applied pharmacology 19961101
Decreased connexin32 and a characteristic enzyme phenotype in clofibrate-induced preneoplastic lesions not shared with spontaneously occurring lesions in the rat liver. Carcinogenesis 19961101
Role of the pituitary in tumor promotion with ethinyl estradiol in rat liver. Hepatology (Baltimore, Md.) 19961001
Cell proliferation and regulation of negative growth factors in mouse liver foci. Carcinogenesis 19960901
Enhancement of N-nitrosodiethylamine-initiated hepatocarcinogenesis caused by a colchicine-induced cell cycle disturbance in partially hepatectomized rats. Cancer research 19960801
Reversibility of promoter induced hepatic focal lesion growth in mice. Carcinogenesis 19960701
Dose dependence of phenobarbital promotion of preneoplastic hepatic lesions in F344 rats and B6C3F1 mice: effects on DNA synthesis and apoptosis. Carcinogenesis 19960501
The effect of tamoxifen and two of its non-isomerizable fixed-ring analogs on multistage rat hepatocarcinogenesis. Carcinogenesis 19960301
Increased oxidative DNA damage in livers of 2,3,7,8-tetrachlorodibenzo-p-dioxin treated intact but not ovariectomized rats. Cancer letters 19960102
Phenobarbital selectively promotes initiated cells with reduced TGF beta receptor levels. Carcinogenesis 19960101
Immunohistochemical demonstration of the gap junctional protein connexin 32 and proliferating cell nuclear antigen in glutathione S-transferase placental form-negative lesions of rat liver induced by diethylnitrosamine and clofibrate. Toxicologic pathology 19960101
Inhibitory effects of 1-O-hexyl-2,3,5-trimethylhydroquinone (HTHQ), green tea catechins and other antioxidants on 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole (Glu-P-1)-induced rat hepatocarcinogenesis and dose-dependent inhibition by HTHQ of lesion induction by Glu-P-1 or 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx). Carcinogenesis 19951201
Expression of c-myc in altered hepatic foci induced in rats by various single doses of diethylnitrosamine and promotion by 0.05% phenobarbital. Molecular carcinogenesis 19951101
Promotion of N-nitrosodiethylamine-initiated hepatocellular tumors and hepatoblastomas by 2,3,7,8-tetrachlorodibenzo-p-dioxin or Aroclor 1254 in C57BL/6, DBA/2, and B6D2F1 mice. Cancer research 19951101
Comparison of the effects of tamoxifen and toremifene on liver and kidney tumor promotion in female rats. Carcinogenesis 19951101
Quantitative analysis of multiple phenotype enzyme-altered foci in rat hepatocarcinogenesis experiments: the multipath/multistage model. Carcinogenesis 19951001
Inhibitory effect of vanadium on rat liver carcinogenesis initiated with diethylnitrosamine and promoted by phenobarbital. British journal of cancer 19950601
Gender-dependent differences in hepatic tumor promotion in diethylnitrosamine initiated infant B6C3F1 mice by alpha-hexachlorocyclohexane. Journal of toxicology and environmental health 19950201
Analysis of the potential carcinogenicity of coffee and its related compounds in a medium-term liver bioassay of rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 19950101
Transforming growth factor-beta receptors type I, II and III in phenobarbital-promoted rat liver tumors. Carcinogenesis 19941201
Evaluation of the tumor-promoting activity of two beta-adrenoreceptor blocking agents, propranolol and atenolol, in liver of Fischer 344 rats. Carcinogenesis 19941101
Rapid development of hepatic tumors in transforming growth factor alpha transgenic mice associated with increased cell proliferation in precancerous hepatocellular lesions initiated by N-nitrosodiethylamine and promoted by phenobarbital. Carcinogenesis 19940901
Incorporation of bromodeoxyuridine in glutathione S-transferase-positive hepatocytes during rat multistage hepatocarcinogenesis. Carcinogenesis 19940901
In vitro and in vivo response of hepatocytes from hepatic nodules to the mitoinhibitory effects of phenobarbital. Carcinogenesis 19940901
Initiator-specific promotion of hepatocarcinogenesis by WY-14,643 and clofibrate. Carcinogenesis 19940801
C-raf expression in early rat liver tumorigenesis after promotion with polychlorinated biphenyls or phenobarbital. Xenobiotica; the fate of foreign compounds in biological systems 19940601
Correlation between S-adenosyl-L-methionine content and production of c-myc, c-Ha-ras, and c-Ki-ras mRNA transcripts in the early stages of rat liver carcinogenesis. Cancer letters 19940429
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