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54856-23-4 | N-Methyl-2-(pyridin-2-yl)ethanamine methanesulfonate
CAS No: 54856-23-4 Catalog No: AG003O67 MDL No:MFCD00143688
Product Description
Catalog Number:
AG003O67
Chemical Name:
N-Methyl-2-(pyridin-2-yl)ethanamine methanesulfonate
CAS Number:
54856-23-4
Molecular Formula:
C9H16N2O3S
Molecular Weight:
232.2999
MDL Number:
MFCD00143688
IUPAC Name:
methanesulfonic acid;N-methyl-2-pyridin-2-ylethanamine
InChI:
InChI=1S/C8H12N2.2CH4O3S/c1-9-7-5-8-4-2-3-6-10-8;2*1-5(2,3)4/h2-4,6,9H,5,7H2,1H3;2*1H3,(H,2,3,4)
InChI Key:
ZBJJDYGJCNTNTH-UHFFFAOYSA-N
SMILES:
CS(=O)(=O)O.CNCCc1ccccn1
EC Number:
259-377-7
UNII:
X1L0E3R43Y
Properties
Complexity:
176
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
3
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
328.076g/mol
Formal Charge:
0
Heavy Atom Count:
20
Hydrogen Bond Acceptor Count:
8
Hydrogen Bond Donor Count:
3
Isotope Atom Count:
0
Molecular Weight:
328.398g/mol
Monoisotopic Mass:
328.076g/mol
Rotatable Bond Count:
3
Topological Polar Surface Area:
150A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
| Title | Journal |
|---|---|
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| Involvement of histamine receptors in SAPK/JNK phosphorylation. | International immunopharmacology 20120601 |
| Comparison of the therapeutic efficacy of a fixed low-dose combination of cinnarizine and dimenhydrinate with betahistine in vestibular neuritis: a randomized, double-blind, non-inferiority study. | Clinical drug investigation 20120601 |
| Effect of transtympanic low-pressure therapy in patients with unilateral Menière's disease unresponsive to betahistine: a randomised, placebo-controlled, double-blinded, clinical trial. | The Journal of laryngology and otology 20120401 |
| Meniere's disease: an evidence based approach to assessment and management. | International journal of clinical practice 20120201 |
| Development of novel sustained release matrix pellets of betahistine dihydrochloride: effect of lipophilic surfactants and co-surfactants. | Pharmaceutical development and technology 20120101 |
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| Duplicate internal auditory canals with facial and vestibulocochlear nerve dysfunction. | The Journal of laryngology and otology 20120101 |
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| Effects of betahistine at histamine H3 receptors: mixed inverse agonism/agonism in vitro and partial inverse agonism in vivo. | The Journal of pharmacology and experimental therapeutics 20100901 |
| Does betahistine treatment have additional benefits to vestibular rehabilitation? | European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20100801 |
| Comprehensive analysis of MHC class I genes from the U-, S-, and Z-lineages in Atlantic salmon. | BMC genomics 20100101 |
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| Organic functionalization of single-walled carbon nanotubes (SWCNTs) with some chemotherapeutic agents as a potential method for drug delivery. | International journal of nanomedicine 20100101 |
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| Effect of treatment with betahistine dihydrochloride on the postural stability in patients with different duration of benign paroxysmal positional vertigo. | The international tinnitus journal 20100101 |
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| Stress degradation studies on betahistine and development of a validated stability-indicating assay method. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080615 |
| Efficacy of a home-based exercise program on benign paroxysmal positional vertigo compared with betahistine. | Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale 20080601 |
| Long-term prophylactic treatment of attacks of vertigo in Menière's disease--comparison of a high with a low dosage of betahistine in an open trial. | Acta oto-laryngologica 20080501 |
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| Multimodal therapy for chronic tinnitus. | The international tinnitus journal 20080101 |
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| Disability in patients with Menière's disease following the use of two different treatment modalities: betahistine and intratympanic gentamicin. | Revue de laryngologie - otologie - rhinologie 20080101 |
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| Betahistine increases ACh release from the cortex, but not histamine release from the nucleus basalis magnocellularis of freely-moving rats. 2. Histaminergic mechanisms in the CNS. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20060401 |
| [Efficacy of Betahistine Mesilate combined with Flunarizine Hydrochloride for treating tinnitus]. | Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery 20060401 |
| [Assessment of betahistine dihydrochloride effectiveness in the treatment of vertigo of a different aetiology based on videonystagmography test results]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20060301 |
| [Betaserc in the treatment of vestibular dysfunctions of different etiology]. | Vestnik otorinolaringologii 20060101 |
| Betahistine: a retrospective synopsis of safety data. | Drug safety 20060101 |
| [Betaserk in therapy of cochleovestibular disordes]. | Vestnik otorinolaringologii 20060101 |
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| Dose- and duration-dependent effects of betahistine dihydrochloride treatment on histamine turnover in the cat. | European journal of pharmacology 20051031 |
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| The effect of betahistine, a histamine H1 receptor agonist/H3 antagonist, on olanzapine-induced weight gain in first-episode schizophrenia patients. | International clinical psychopharmacology 20050301 |
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| [Betaserc and improvement of life quality in war veterans]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20050101 |
| [Betaserk in the treatment of aftereffects of craniocerebral injury and vascular events]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20050101 |
| [Epidemiology, clinical features and betaserc therapy of vertigo in initial and reversible cerebrovascular pathology]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20050101 |
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| [Rehabilitation of patients with peripheral vestibular disorders]. | Vestnik otorinolaringologii 20040101 |
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| [Pharmacological correction of cochleovestibular impairments]. | Vestnik otorinolaringologii 20040101 |
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