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CAS No: 546-88-3 Catalog No: AG0038NO MDL No:MFCD00009994
Title | Journal |
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Growth-inhibiting, bactericidal, and urease inhibitory effects of Paeonia lactiflora root constituents and related compounds on antibiotic-susceptible and -resistant strains of Helicobacter pylori. | Journal of agricultural and food chemistry 20120912 |
Characterization of cobalt(III) hydroxamic acid complexes based on a tris(2-pyridylmethyl)amine scaffold: reactivity toward cysteine methyl ester. | Inorganic chemistry 20120903 |
Amelioration of metal-induced toxicity in Caenorhabditis elegans: utility of chelating agents in the bioremediation of metals. | Toxicological sciences : an official journal of the Society of Toxicology 20120901 |
Synthesis, biological evaluation, and molecular docking studies of 2,5-substituted-1,4-benzoquinone as novel urease inhibitors. | Bioorganic & medicinal chemistry 20120815 |
Simple pseudo-dipeptides with a P2' glutamate: a novel inhibitor family of matrix metalloproteases and other metzincins. | The Journal of biological chemistry 20120803 |
Synthesis, inhibitory activity and molecular docking studies of two Cu(II) complexes against Helicobacter pylori urease. | Journal of enzyme inhibition and medicinal chemistry 20120801 |
Studies of histidine residues in soybean (Glycine max) urease. | Protein and peptide letters 20120601 |
N-substituted aminomethanephosphonic and aminomethane-P-methylphosphinic acids as inhibitors of ureases. | Amino acids 20120501 |
The physiological implications of urease inhibitors on N metabolism during germination of Pisum sativum and Spinacea oleracea seeds. | Journal of plant physiology 20120501 |
Modulation of Wnt/β-catenin signaling and proliferation by a ferrous iron chelator with therapeutic efficacy in genetically engineered mouse models of cancer. | Oncogene 20120112 |
Enhanced Bioavailability and Dissolution of Atorvastatin Calcium from Floating Microcapsules using Minimum Additives. | Scientia pharmaceutica 20120101 |
Chitosan-alginate microcapsules of amoxicillin for gastric stability and mucoadhesion. | Journal of advanced pharmaceutical technology & research 20120101 |
Allosteric effects of sulfonate anions on the rates of iron release from serum transferrin. | Journal of inorganic biochemistry 20110901 |
Bis(acetohydroxamato-κO,O')diphenyl-tin(IV). | Acta crystallographica. Section E, Structure reports online 20110801 |
Novel lipophilic acetohydroxamic acid derivatives based on conformationally constrained spiro carbocyclic 2,6-diketopiperazine scaffolds with potent trypanocidal activity. | Journal of medicinal chemistry 20110728 |
Urease inhibitors as potential drugs for gastric and urinary tract infections: a patent review. | Expert opinion on therapeutic patents 20110601 |
An improved bioprocess for synthesis of acetohydroxamic acid using DTT (dithiothreitol) treated resting cells of Bacillus sp. APB-6. | Bioresource technology 20110601 |
One-electron oxidation of acetohydroxamic acid: the intermediacy of nitroxyl and peroxynitrite. | The journal of physical chemistry. A 20110414 |
Identifying chelators for metalloprotein inhibitors using a fragment-based approach. | Journal of medicinal chemistry 20110127 |
Structural and functional role of nickel ions in urease by molecular dynamics simulation. | Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20110101 |
Amoxicillin loaded chitosan-alginate polyelectrolyte complex nanoparticles as mucopenetrating delivery system for h. Pylori. | Scientia pharmaceutica 20110101 |
The synthesis, structure and activity evaluation of pyrogallol and catechol derivatives as Helicobacter pylori urease inhibitors. | European journal of medicinal chemistry 20101101 |
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
Synthesis, molecular docking and biological evaluation of Schiff base transition metal complexes as potential urease inhibitors. | European journal of medicinal chemistry 20101001 |
Computer-aided optimization of phosphinic inhibitors of bacterial ureases. | Journal of medicinal chemistry 20100812 |
Synthesis, structures, and urease inhibitory activities of three copper(II) and zinc(II) complexes with 2-{[2-(2-hydroxyethylamino)ethylimino]methyl}-4-nitrophenol. | European journal of medicinal chemistry 20100701 |
Entropic contribution to the linking coefficient in fragment based drug design: a case study. | Journal of medicinal chemistry 20100527 |
X-ray absorption spectroscopy of aqueous aluminum-organic complexes. | The journal of physical chemistry. A 20100527 |
Inhibitors of human histone deacetylase: synthesis and enzyme assay of hydroxamates with piperazine linker. | Archiv der Pharmazie 20100301 |
13[C]-urea breath test as a novel point-of-care biomarker for tuberculosis treatment and diagnosis. | PloS one 20100101 |
Redox reactions of Pu(IV) and Pu(III) in the presence of acetohydroxamic acid in HNO(3) solutions. | Inorganic chemistry 20091221 |
The interaction of zinc(II) and hydroxamic acids and a metal-triggered Lossen rearrangement. | Chemistry (Weinheim an der Bergstrasse, Germany) 20091214 |
Lipoamide dehydrogenase and diaphorase catalyzed conversion of some NO donors to NO and reduction of NO scavenger 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide (PTIO). | General physiology and biophysics 20091201 |
Inhibitors of bacterial N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE) and demonstration of in vitro antimicrobial activity. | Bioorganic & medicinal chemistry letters 20091115 |
Medical treatment of pediatric urolithiasis. | Pediatric nephrology (Berlin, Germany) 20091101 |
Synthesis, molecular docking and biological evaluation of metronidazole derivatives as potent Helicobacter pylori urease inhibitors. | Bioorganic & medicinal chemistry 20091101 |
Hydroxamic acids as a novel family of serine racemase inhibitors: mechanistic analysis reveals different modes of interaction with the pyridoxal-5'-phosphate cofactor. | Journal of medicinal chemistry 20091008 |
Amines and oximes derived from deoxybenzoins as Helicobacter pylori urease inhibitors. | European journal of medicinal chemistry 20090501 |
Adsorption of hydroxamate siderophores and EDTA on goethite in the presence of the surfactant sodium dodecyl sulfate. | Geochemical transactions 20090101 |
Heart protection by ischemic preconditioning: a novel pathway initiated by iron and mediated by ferritin. | Journal of molecular and cellular cardiology 20081201 |
Design, synthesis, and evaluation of novel organophosphorus inhibitors of bacterial ureases. | Journal of medicinal chemistry 20080925 |
Extended triple-bridged Ni(II)- and Co(II)-hydroxamate trinuclear complexes: synthesis, crystal structures, and magnetic properties. | Inorganic chemistry 20080804 |
Reduction of pertechnetate by acetohydroxamic acid: formation of [TcII(NO)(AHA)2(H2O)]+ and implications for the UREX process. | Inorganic chemistry 20080804 |
Chelated iron sources are inhibitors of Pseudomonas aeruginosa biofilms and distribute efficiently in an in vitro model of drug delivery to the human lung. | Journal of applied microbiology 20080801 |
Immobilised metal affinity chromatography for the capture of hydroxamate-containing siderophores and other Fe(III)-binding metabolites directly from bacterial culture supernatants. | The Analyst 20080701 |
Floating in situ gelling system of acetohydroxamic acid for clearance of H. pylori. | Drug development and industrial pharmacy 20080601 |
Enzymatic, immunological and phylogenetic characterization of Brucella suis urease. | BMC microbiology 20080101 |
Vasorelaxant activity of some oxime derivatives. | European journal of pharmacology 20071201 |
Preparation and in vitro characterization of gellan based floating beads of acetohydroxamic acid for eradication of H. pylori. | Acta pharmaceutica (Zagreb, Croatia) 20071201 |
Jack bean urease: the effect of active-site binding inhibitors on the reactivity of enzyme thiol groups. | Bioorganic chemistry 20071001 |
A membrane associated metalloprotease cleaves Cry3Aa Bacillus thuringiensis toxin reducing pore formation in Colorado potato beetle brush border membrane vesicles. | Biochimica et biophysica acta 20070901 |
Design of novel histone deacetylase inhibitors. | Bioorganic & medicinal chemistry letters 20070815 |
Benzo[b]thiophene-based histone deacetylase inhibitors. | Bioorganic & medicinal chemistry letters 20070815 |
Spectroscopic study of the uranyl-acetohydroxamate adduct with tributyl phosphate. | Applied spectroscopy 20070701 |
Polyphenols based on isoflavones as inhibitors of Helicobacter pylori urease. | Bioorganic & medicinal chemistry 20070601 |
Exploring the subtleties of drug-receptor interactions: the case of matrix metalloproteinases. | Journal of the American Chemical Society 20070307 |
Laccase induction in fungi and laccase/N-OH mediator systems applied in paper mill effluent. | Bioresource technology 20070101 |
Simultaneous Determination of Cobalt(II) and Nickel(II) by Fourth-Order Derivative Spectrophotometric Method Using 2-Hydroxy-3-Methoxy Benzaldehyde Thiosemicarbazone. | Journal of automated methods & management in chemistry 20070101 |
Interaction of imidazole containing hydroxamic acids with Fe(III): hydroxamate versus imidazole coordination of the ligands. | Bioinorganic chemistry and applications 20070101 |
Bioactive oligostilbenoids from the stem bark of Hopea exalata. | Journal of natural products 20061201 |
Infrared spectroscopic studies of siderophore-related hydroxamic acid ligands adsorbed on titanium dioxide. | Langmuir : the ACS journal of surfaces and colloids 20061121 |
Synthesis of bicyclic molecular scaffolds (BTAa): an investigation towards new selective MMP-12 inhibitors. | Bioorganic & medicinal chemistry 20061115 |
Near edge X-ray absorption fine structure spectroscopy of bacterial hydroxamate siderophores in aqueous solutions. | The journal of physical chemistry. A 20061026 |
Floating hot-melt extruded tablets for gastroretentive controlled drug release system. | Journal of controlled release : official journal of the Controlled Release Society 20061010 |
N-hydroxyurea--a versatile zinc binding function in the design of metalloenzyme inhibitors. | Bioorganic & medicinal chemistry letters 20060815 |
Di-, tri-, and tetranuclear zinc hydroxamate complexes as structural models for the inhibition of zinc hydrolases by hydroxamic acids. | Inorganic chemistry 20060529 |
Synthesis and antibacterial activity of novel oxazolidinones bearing N-hydroxyacetamidine substituent. | Bioorganic & medicinal chemistry letters 20060501 |
Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
Towards third generation matrix metalloproteinase inhibitors for cancer therapy. | British journal of cancer 20060410 |
A new role for old ligands: discerning chelators for zinc metalloproteinases. | Journal of the American Chemical Society 20060315 |
Heterocyclic zinc-binding groups for use in next-generation matrix metalloproteinase inhibitors: potency, toxicity, and reactivity. | Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20060301 |
Alcohol and oxidative liver injury. | Hepatology (Baltimore, Md.) 20060201 |
Characterization and optimization of experimental variables within a reproducible bladder encrustation model and in vitro evaluation of the efficacy of urease inhibitors for the prevention of medical device-related encrustation. | Journal of biomedical materials research. Part B, Applied biomaterials 20060101 |
Pb(II)-binding capability of aminohydroxamic acids: primary hydroxamic acid derivatives of alpha-amino acids as possible sequestering agents for Pb(II). | Journal of inorganic biochemistry 20060101 |
Hard and soft X-ray absorption spectroscopic investigation of aqueous Fe(III)-hydroxamate siderophore complexes. | The journal of physical chemistry. A 20051117 |
Application of Fourier transform infrared spectroscopy for monitoring hydrolysis and synthesis reactions catalyzed by a recombinant amidase. | Analytical biochemistry 20051101 |
Chemistry of a Ni(II) acetohydroxamic acid complex: formation, reactivity with water, and attempted preparation of zinc and cobalt analogues. | Inorganic chemistry 20051003 |
DFT study of the V(IV)/V(V) oxidation mechanism in the presence of N-hydroxyacetamide. | Journal of inorganic biochemistry 20050801 |
Dimerization of the keto tautomer of acetohydroxamic acid-infrared matrix isolation and theoretical study. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050501 |
Release of iron from ferritin by aceto- and benzohydroxamic acids. | Inorganic chemistry 20050418 |
Neutral acetohydroxamic acid coordination to a mononuclear Ni(II) center stabilized by an intramolecular hydrogen-bonding interaction. | Chemical communications (Cambridge, England) 20050128 |
Ternary ligand-zinc-hydroxamate complexes. | Inorganic chemistry 20050110 |
Urease-induced alkalinization of extracellular pH and its antitumor activity in human breast and lung cancers. | Journal of experimental therapeutics & oncology 20050101 |
Pyrazolylborate-zinc alkoxide complexes. 3. Acid-base reactions. | Inorganic chemistry 20040920 |
Receptor-mediated targeting of lipobeads bearing acetohydroxamic acid for eradication of Helicobacter pylori. | Journal of controlled release : official journal of the Controlled Release Society 20040914 |
Crystal structures of novel non-peptidic, non-zinc chelating inhibitors bound to MMP-12. | Journal of molecular biology 20040820 |
Mechanism of metal-mediated DNA damage induced by a metabolite of carcinogenic acetamide. | Chemico-biological interactions 20040810 |
Acetohydroxamate inhibition of the activity of urease from dehusked seeds of water melon (Citrullus vulgaris). | Journal of enzyme inhibition and medicinal chemistry 20040801 |
New beginnings for matrix metalloproteinase inhibitors: identification of high-affinity zinc-binding groups. | Journal of the American Chemical Society 20040714 |
Synthesis, antiprotozoal and cytotoxic activities of new N-(3,4-dimethyl-5-isoxazolyl)-1,2-naphthoquinone-4-amino derivatives. | Farmaco (Societa chimica italiana : 1989) 20040601 |
Soybean cultivars 'Williams 82' and 'Maple Arrow' produce both urea and ammonia during ureide degradation. | Journal of experimental botany 20040401 |
Jackbean, soybean and Bacillus pasteurii ureases: biological effects unrelated to ureolytic activity. | European journal of biochemistry 20040401 |
Relaxant effect of oxime derivatives in isolated rat aorta: role of nitric oxide (NO) formation in smooth muscle. | Biochemical pharmacology 20040315 |
Predominant role of basicity of leaving group in alpha-effect for nucleophilic ester cleavage. | Bioorganic chemistry 20040201 |
Floating microspheres bearing acetohydroxamic acid for the treatment of Helicobacter pylori. | The Journal of pharmacy and pharmacology 20031201 |
First row divalent transition metal complexes of aryl-appended tris((pyridyl)methyl)amine ligands: syntheses, structures, electrochemistry, and hydroxamate binding properties. | Inorganic chemistry 20031117 |
Deprotonation sites of acetohydroxamic acid isomers. A theoretical and experimental study. | The Journal of organic chemistry 20030822 |
Receptor mediated targeting of lectin conjugated gliadin nanoparticles in the treatment of Helicobacter pylori. | Journal of drug targeting 20030801 |
Kinetics and mechanism of iron(III)-nitrilotriacetate complex reactions with phosphate and acetohydroxamic acid. | Inorganic chemistry 20030630 |
Potentiometric, spectrophotometric and density functional study of the interaction of N-hydroxyacetamide with oxovanadium(IV): the influence of ligand to the V(IV)/V(V) oxi-reduction reaction. | Journal of inorganic biochemistry 20030501 |
Catalysis of the beta-elimination of HF from isomeric 2-fluoroethylpyridines and 1-methyl-2-fluoroethylpyridinium salts. Proton-activating factors and methyl-activating factors as a mechanistic test to distinguish between concerted E2 and E1cb irreversible mechanisms. | The Journal of organic chemistry 20030207 |
A new approach in gastroretentive drug delivery system using cholestyramine. | Drug delivery 20030101 |
[Antimicrobial action of ammonium salts of fused heterocycles containing ortho-nitrogen]. | Medicina (Kaunas, Lithuania) 20030101 |
NMR-based modification of matrix metalloproteinase inhibitors with improved bioavailability. | Journal of medicinal chemistry 20021219 |
Elucidating drug-metalloprotein interactions with tris(pyrazolyl)borate model complexes. | Inorganic chemistry 20021007 |
Design and synthesis of novel inhibitors of gelatinase B. | Bioorganic & medicinal chemistry letters 20020819 |
Dianionic complexes with hexacoordinate silicon(IV) or germanium(IV) and three bidentate ligands of the hydroximato(2-) type: syntheses and structural characterization in the solid state. | Inorganic chemistry 20020729 |
A novel general route for the preparation of enantiopure imidazolines. | The Journal of organic chemistry 20020531 |
Formation and structure of 1:1 complexes between aryl hydroxamic acids and vanadate at neutral pH. | Inorganic chemistry 20020520 |
Acetamidoquinone and acetamidohydroxy derivatives as inhibitors for both dihydroxyacetamido epoxidase and dehydrogenase. | Bioorganic & medicinal chemistry 20020501 |
Thermodynamics, kinetics, and mechanism of the stepwise dissociation and formation of Tris(L-lysinehydroxamato)iron(III) in aqueous acid. | Inorganic chemistry 20020325 |
Urease activity in microbiologically-induced calcite precipitation. | Journal of biotechnology 20020214 |
Purification and characterization of urease isolated from the pathogenic fungus Coccidioides immitis. | Medical mycology 20020201 |
Suppression of Helicobacter pylori-induced gastritis by urease inhibitors in Mongolian gerbils. | Gan to kagaku ryoho. Cancer & chemotherapy 20020201 |
Kinetics of inhibition and molecular asymmetry in pigeonpea (Cajanus cajan) urease. | Journal of biochemistry, molecular biology, and biophysics : JBMBB : the official journal of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) 20020201 |
Inhibition of bacteriophage lambda protein phosphatase by organic and oxoanion inhibitors. | Biochemistry 20020122 |
Floating-bioadhesive microspheres containing acetohydroxamic acid for clearance of Helicobacter pylori. | Drug delivery 20020101 |
Magnetic, spectroscopic, and structural studies of dicobalt hydroxamates and model hydrolases. | Inorganic chemistry 20011105 |
Marked reduction of Helicobacter pylori-induced gastritis by urease inhibitors, acetohydroxamic acid and flurofamide, in Mongolian gerbils. | Biochemical and biophysical research communications 20010720 |
Identification of novel potent hydroxamic acid inhibitors of peptidyl deformylase and the importance of the hydroxamic acid functionality on inhibition. | Bioorganic & medicinal chemistry letters 20010604 |
Supramolecular assembly and acid resistance of Helicobacter pylori urease. | Nature structural biology 20010601 |
Structure-based computational study of the catalytic and inhibition mechanisms of urease. | Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20010301 |
Interaction between iron(II) and hydroxamic acids: oxidation of iron(II) to iron(III) by desferrioxamine B under anaerobic conditions. | Journal of inorganic biochemistry 20010115 |
Synergistic binding of ligands to angiotensin-converting enzyme. | The Journal of biological chemistry 19880325 |
N-hydroxy-2-acetylaminofluorene as effective inhibitor of aldehyde oxidase. | Biochemical and biophysical research communications 19860716 |
Microsome- and hepatocyte-mediated mutagenicity of hydroxyurea and related aliphatic hydroxamic acids in V79 Chinese hamster cells. | Mutation research 19850101 |
Inhibition of urease by miscellaneous ions and compounds. Implications for the therapy of infection-induced urolithiasis. | Investigative urology 19770901 |
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