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541-59-3

541-59-3 | Maleimide

CAS No: 541-59-3 Catalog No: AG00354C MDL No:MFCD00005494

Product Description

Catalog Number:
AG00354C
Chemical Name:
Maleimide
CAS Number:
541-59-3
Molecular Formula:
C4H3NO2
Molecular Weight:
97.0721
MDL Number:
MFCD00005494
IUPAC Name:
pyrrole-2,5-dione
InChI:
InChI=1S/C4H3NO2/c6-3-1-2-4(7)5-3/h1-2H,(H,5,6,7)
InChI Key:
PEEHTFAAVSWFBL-UHFFFAOYSA-N
SMILES:
O=C1C=CC(=O)N1
EC Number:
208-787-4
UNII:
2519R1UGP8
NSC Number:
13684

Properties

Complexity:
132  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
97.016g/mol
Formal Charge:
0
Heavy Atom Count:
7  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
97.073g/mol
Monoisotopic Mass:
97.016g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
46.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.3  

Literature

Title Journal
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Estimation of cell membrane properties and erythrocyte red-ox balance in patients with metabolic syndrome. Molecular biology reports 20121201
Facile functionalization of HTC-derived carbon microspheres. Chemical communications (Cambridge, England) 20121118
Vapor-based synthesis of maleimide-functionalized coating for biointerface engineering. Chemical communications (Cambridge, England) 20121118
Easy introduction of maleimides at different positions of oligonucleotide chains for conjugation purposes. Organic & biomolecular chemistry 20121114
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Protein labeling with the labeling precursor [(18)F]SiFA-SH for positron emission tomography. Nature protocols 20121101
A humanised mouse model of cytokine release: comparison of CD3-specific antibody fragments. Journal of immunological methods 20121031
Immobilization of enterokinase on magnetic supports for the cleavage of fusion proteins. Journal of biotechnology 20121031
Evaluation of chemically modified carrier proteins for developing monoclonal antibodies against a clinically relevant mutation of cKIT. Journal of immunological methods 20121031
Surface modification of siliceous materials using maleimidation and various functional polymers synthesized by reversible addition-fragmentation chain transfer polymerization. ACS applied materials & interfaces 20121024
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A simple, rapid and inexpensive technique to bind small peptides to polystyrene surfaces for immunoenzymatic assays. Journal of immunological methods 20120831
Photochemical dynamics of indolylmaleimide derivatives. Physical chemistry chemical physics : PCCP 20120828
Thiol-ene click chemistry: computational and kinetic analysis of the influence of alkene functionality. Journal of the American Chemical Society 20120822
Improved methodology for the preparation of water-soluble maleimide-functionalized small gold nanoparticles. Langmuir : the ACS journal of surfaces and colloids 20120821
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Stereoselection in the Diels-Alderase ribozyme: a molecular dynamics study. Journal of computational chemistry 20120715
Identification of specific features of inhibition of PKCβII and its potential lead by shape-based virtual screening and molecular docking studies. Bioorganic & medicinal chemistry letters 20120715
Separation and detection of bis-maleimide-polyethylene glycol and mono-maleimide-polyethylene glycol by reversed-phase high pressure liquid chromatography. Journal of chromatography. A 20120713
Selective detection of the reduced form of glutathione (GSH) over the oxidized (GSSG) form using a combination of glutathione reductase and a Tb(III)-cyclen maleimide based lanthanide luminescent 'switch on' assay. Journal of the American Chemical Society 20120704
Zosuquidar and an albumin-binding prodrug of zosuquidar reverse multidrug resistance in breast cancer cells of doxorubicin and an albumin-binding prodrug of doxorubicin. Breast cancer research and treatment 20120701
Development of novel linkers to conjugate pharmacophores to a carrier antibody. Bioorganic & medicinal chemistry letters 20120701
1-(2-Meth-oxy-phen-yl)-1H-pyrrole-2,5-dione. Acta crystallographica. Section E, Structure reports online 20120701
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Thermostable DNA immobilization and temperature effects on surface hybridization. Langmuir : the ACS journal of surfaces and colloids 20120605
Albumin-binding domain conjugate for near-infrared fluorescence lymphatic imaging. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20120601
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Post-synthetic modification of Zr-metal-organic frameworks through cycloaddition reactions. Chemistry (Weinheim an der Bergstrasse, Germany) 20120529
A model-structure of a periplasm-facing state of the NhaA antiporter suggests the molecular underpinnings of pH-induced conformational changes. The Journal of biological chemistry 20120525
Identification of novel liver X receptor activators by structure-based modeling. Journal of chemical information and modeling 20120525
Different functions of MdtB and MdtC subunits in the heterotrimeric efflux transporter MdtB(2)C complex of Escherichia coli. Biochemistry 20120522
[2+2] photocycloadditions of thiomaleimides. Chemical communications (Cambridge, England) 20120516
Design and synthesis of novel 'orthogonally' functionalizable maleimide-based styrenic copolymers. Macromolecular rapid communications 20120514
Diaminoterephthalate turn-on fluorescence probes for thiols--tagging of recoverin and tracking of its conformational change. Chembiochem : a European journal of chemical biology 20120507
Preclinical evaluation of anti-HER2 Affibody molecules site-specifically labeled with 111In using a maleimido derivative of NODAGA. Nuclear medicine and biology 20120501
3,4-Bis(4-meth-oxy-phen-yl)-2,5-dihydro-1H-pyrrole-2,5-dione. Acta crystallographica. Section E, Structure reports online 20120501
One pot synthesis of maleimide and hydantoin by Fe(CO)5 catalyzed [2 + 2 + 1] co-cyclization of acetylene, isocyanate and CO. Dalton transactions (Cambridge, England : 2003) 20120428
Highly efficient disulfide bridging polymers for bioconjugates from radical-compatible dithiophenol maleimides. Chemical communications (Cambridge, England) 20120428
Escherichia coli TatA and TatB proteins have N-out, C-in topology in intact cells. The Journal of biological chemistry 20120427
Real-time sensing and discrimination of single chemicals using the channel of phi29 DNA packaging nanomotor. ACS nano 20120424
Rotaxanes and biofunctionalized pseudorotaxanes via thiol-maleimide click chemistry. Organic letters 20120420
Site-specific fluorescent labeling and oriented immobilization of a triple mutant of CYP3A4 via C64. Bioconjugate chemistry 20120418
Immobilization of hydrophobic peptidic ligands to hydrophilic chromatographic matrix: a preconcentration approach. Analytical biochemistry 20120415
Characterization of maleimide dimers in photo-cross-linked copolyimide films. Physical chemistry chemical physics : PCCP 20120407
Accurate prediction of rate constants of Diels-Alder reactions and application to design of Diels-Alder ligation. Organic & biomolecular chemistry 20120407
Inhibition of cell survival, cell cycle progression, tumor growth and cyclooxygenase-2 activity in MDA-MB-231 breast cancer cells by camphorataimide B. European journal of pharmacology 20120405
Preparation of water-soluble maleimide-functionalized 3 nm gold nanoparticles: a new bioconjugation template. Langmuir : the ACS journal of surfaces and colloids 20120403
Physical characterization of the 'immunosignaturing effect'. Molecular & cellular proteomics : MCP 20120401
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Assembly of protein building blocks using a short synthetic peptide. Bioconjugate chemistry 20120321
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Dual peptide nucleic acid- and peptide-functionalized shell cross-linked nanoparticles designed to target mRNA toward the diagnosis and treatment of acute lung injury. Bioconjugate chemistry 20120321
Target-activated coumarin phototriggers specifically switch on fluorescence and photocleavage upon bonding to thiol-bearing protein. Journal of the American Chemical Society 20120321
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SUMO modification of the neuroprotective protein TDP1 facilitates chromosomal single-strand break repair. Nature communications 20120313
A chromenoquinoline-based fluorescent off-on thiol probe for bioimaging. Chemical communications (Cambridge, England) 20120311
Theoretical study of photo-physical properties of indolylmaleimide derivatives. Physical chemistry chemical physics : PCCP 20120307
Preparation of cystamine core dendrimer and antibody-dendrimer conjugates for MRI angiography. Molecular pharmaceutics 20120305
Oxidation of 2-hydroxynevirapine, a phenolic metabolite of the anti-HIV drug nevirapine: evidence for an unusual pyridine ring contraction. Molecules (Basel, Switzerland) 20120305
High-throughput fluorescence polarization assay for chemical library screening against anti-apoptotic Bcl-2 family member Bfl-1. Journal of biomolecular screening 20120301
18F-radiolabeled analogs of exendin-4 for PET imaging of GLP-1 in insulinoma. European journal of nuclear medicine and molecular imaging 20120301
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Preferential entry of botulinum neurotoxin A Hc domain through intestinal crypt cells and targeting to cholinergic neurons of the mouse intestine. PLoS pathogens 20120301
Conjugation reactions involving maleimides and phosphorothioate oligonucleotides. Bioconjugate chemistry 20120215
Development and characterization of immuno-nanocarriers targeting the cancer stem cell marker AC133. International journal of pharmaceutics 20120214
The human ZIP4 transporter has two distinct binding affinities and mediates transport of multiple transition metals. Biochemistry 20120207
Chemical reactivity and antimicrobial activity of N-substituted maleimides. Journal of enzyme inhibition and medicinal chemistry 20120201
Maleimide-functionalised organoruthenium anticancer agents and their binding to thiol-containing biomolecules. Chemical communications (Cambridge, England) 20120201
Maleimide-thiol coupling of a bioactive peptide to an elastin-like protein polymer. Acta biomaterialia 20120201
Inhibition of 5-lipoxygenase by U73122 is due to covalent binding to cysteine 416. Biochimica et biophysica acta 20120201
Ethyl 2-benzyl-3-[3-(4-chloro-phen-yl)-1-phenyl-1H-pyrazol-4-yl]-4,6-dioxo-5-phenyl-octa-hydro-pyrrolo-[3,4-c]pyrrole-1-carboxyl-ate. Acta crystallographica. Section E, Structure reports online 20120201
Polyplex-microbubble hybrids for ultrasound-guided plasmid DNA delivery to solid tumors. Journal of controlled release : official journal of the Controlled Release Society 20120130
Polymeric dibromomaleimides as extremely efficient disulfide bridging bioconjugation and pegylation agents. Journal of the American Chemical Society 20120125
Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates. Nature biotechnology 20120122
Hydrogen-bonding-driven self-assembly of PEGylated organosilica nanoparticles with poly(acrylic acid) in aqueous solutions and in layer-by-layer deposition at solid surfaces. Langmuir : the ACS journal of surfaces and colloids 20120110
Maleimide cross-linked bioactive PEG hydrogel exhibits improved reaction kinetics and cross-linking for cell encapsulation and in situ delivery. Advanced materials (Deerfield Beach, Fla.) 20120103
Probing binding pocket of serotonin transporter by single molecular force spectroscopy on living cells. The Journal of biological chemistry 20120102
Bromomaleimide-linked bioconjugates are cleavable in mammalian cells. Chembiochem : a European journal of chemical biology 20120102
Carbohydrate microarrays for enzymatic reactions and quantification of binding affinities for glycan-protein interactions. Methods in molecular biology (Clifton, N.J.) 20120101
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Control of gastric H,K-ATPase activity by cations, voltage and intracellular pH analyzed by voltage clamp fluorometry in Xenopus oocytes. PloS one 20120101
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Covalently stabilized trimethyl chitosan-hyaluronic acid nanoparticles for nasal and intradermal vaccination. Journal of controlled release : official journal of the Controlled Release Society 20111130
Durability studies shed light on the design of novel self-healing artificial muscles by employing ionic network polymers. Journal of controlled release : official journal of the Controlled Release Society 20111130
Thermosensitive dendrimer formulation for drug delivery at physiologically relevant temperatures. Chemical communications (Cambridge, England) 20111128
Polymer-coated nanoparticles: a universal tool for biolabelling experiments. Small (Weinheim an der Bergstrasse, Germany) 20111118
The S100A10-annexin A2 complex provides a novel asymmetric platform for membrane repair. The Journal of biological chemistry 20111118
Conjugate addition of 1,3-dicarbonyl compounds to maleimides using a chiral C2-symmetric bis(2-aminobenzimidazole) as recyclable organocatalyst. Organic letters 20111118
The signal-anchor sequence of CYP2C1 inserts into the membrane as a hairpin structure. Biochemical and biophysical research communications 20111118
A molecular umbrella approach to the intracellular delivery of small interfering RNA. Bioconjugate chemistry 20111116
Fluorescence detection of GDP in real time with the reagentless biosensor rhodamine-ParM. The Biochemical journal 20111115
Identification of anchor points for chemical modification of a small cysteine-rich protein by using a cysteine scan. Chembiochem : a European journal of chemical biology 20111104
Development of an enzyme-linked immunosorbent assay analytical platform for refolding yield determination of recombinant hepatitis B virus X (HBx) protein. Analytical biochemistry 20111101
Comparative biodistribution of imaging agents for in vivo molecular profiling of disseminated prostate cancer in mice bearing prostate cancer xenografts: focus on 111In- and 125I-labeled anti-HER2 humanized monoclonal trastuzumab and ABY-025 affibody. Nuclear medicine and biology 20111101
2-(2-Bromo-eth-yl)isoindoline-1,3-dione. Acta crystallographica. Section E, Structure reports online 20111101
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Using self-assembled monolayers to understand α8β1-mediated cell adhesion to RGD and FEI motifs in nephronectin. ACS chemical biology 20111021
Tunable degradation of maleimide-thiol adducts in reducing environments. Bioconjugate chemistry 20111019
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Versatile bio-ink for covalent immobilization of chimeric avidin on sol-gel substrates. Colloids and surfaces. B, Biointerfaces 20111015
One-pot synthesis of cyclopentadienyl endcapped poly(2-ethyl-2-oxazoline) and subsequent ambient temperature Diels-Alder conjugations. Chemical communications (Cambridge, England) 20111014
Substituent effects on the reversibility of furan-maleimide cycloadditions. The Journal of organic chemistry 20111007
S-Glutathionyl quantification in the attomole range using glutaredoxin-3-catalyzed cysteine derivatization and capillary gel electrophoresis with laser-induced fluorescence detection. Analytical and bioanalytical chemistry 20111001
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Highly sensitive detection of S-nitrosylated proteins by capillary gel electrophoresis with laser induced fluorescence. Journal of chromatography. A 20110923
Hepatitis C virus (HCV) envelope glycoproteins E1 and E2 contain reduced cysteine residues essential for virus entry. The Journal of biological chemistry 20110916
Visible light mediated azomethine ylide formation-photoredox catalyzed [3+2] cycloadditions. Chemical communications (Cambridge, England) 20110914
Chemical control of metabolically-engineered voltage-gated K+ channels. Bioorganic & medicinal chemistry letters 20110901
MeCAT--new iodoacetamide reagents for metal labeling of proteins and peptides. Analytical and bioanalytical chemistry 20110901
In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation. Nature medicine 20110901
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Room-temperature Rh-catalyzed asymmetric 1,4-addition of arylboronic acids to maleimides and enones in the presence of CF3-substituted MeOBIPHEP analogues. The Journal of organic chemistry 20110819
Maleimide-dimethylfuran exo adducts: effective maleimide protection in the synthesis of oligonucleotide conjugates. Organic letters 20110819
Thermoreversibly crosslinked poly(ε-caprolactone) as recyclable shape-memory polymer network. Macromolecular rapid communications 20110817
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Selective covalent conjugation of phosphorothioate DNA oligonucleotides with streptavidin. Molecules (Basel, Switzerland) 20110815
Nascent peptide side chains induce rearrangements in distinct locations of the ribosomal tunnel. Journal of molecular biology 20110812
Multi-step surface functionalization of polyimide based evanescent wave photonic biosensors and application for DNA hybridization by Mach-Zehnder interferometer. Analytica chimica acta 20110812
Design of a Pep-1 peptide-modified liposomal nanocarrier system for intracellular drug delivery: Conformational characterization and cellular uptake evaluation. Journal of drug targeting 20110801
In situ forming poly(ethylene glycol)-based hydrogels via thiol-maleimide Michael-type addition. Journal of biomedical materials research. Part A 20110801
Designing a binding interface for control of cancer cell adhesion via 3D topography and metabolic oligosaccharide engineering. Biomaterials 20110801
Insights into the structural requirements of PKCβII inhibitors based on HQSAR and CoMSIA analyses. Chemical biology & drug design 20110801
Investigating the candidacy of lipopolysaccharide-based glycoconjugates as vaccines to combat Mannheimia haemolytica. Glycoconjugate journal 20110801
[Conjugation of Plasmodium falciparum Pfs25 to Pseudomonas aeruginosa ExoProtein A with different chemical linkers]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20110801
Synthesis of mercapto-(+)-methamphetamine haptens and their use for obtaining improved epitope density on (+)-methamphetamine conjugate vaccines. Journal of medicinal chemistry 20110728
Direct fabrication of functional and biofunctional nanostructures through reactive imprinting. Advanced materials (Deerfield Beach, Fla.) 20110726
Reactive semiconductor nanocrystals for chemoselective biolabeling and multiplexed analysis. ACS nano 20110726
Solid-state nanostructured materials from self-assembly of a globular protein-polymer diblock copolymer. ACS nano 20110726
Conjugation of lipid and CpG-containing oligonucleotide yields an efficient method for liposome incorporation. Bioconjugate chemistry 20110720
Post-self-assembly covalent chemistry of discrete multicomponent metallosupramolecular hexagonal prisms. Journal of the American Chemical Society 20110720
Restriction endonuclease SsoII with photoregulated activity--a 'molecular gate' approach. Bioconjugate chemistry 20110720
Effect of wheat germ agglutinin density on cellular uptake and toxicity of wheat germ agglutinin conjugated PEG-PLA nanoparticles in Calu-3 cells. International journal of pharmaceutics 20110715
Synthesis and antidepressant-like activity evaluation of sulphonamides and sulphonyl-hydrazones. Bioorganic & medicinal chemistry 20110715
Recombinant Gaussia luciferase with a reactive cysteine residue for chemical conjugation: expression, purification and its application for bioluminescent immunoassays. Biochemical and biophysical research communications 20110715
Structure-based design of novel boronic acid-based inhibitors of autotaxin. Journal of medicinal chemistry 20110714
Modification of liposomes with proteins by dansyl-labeled heterobifunctional crosslinker. Journal of biomaterials applications 20110701
Thiol-targeted introduction of selenocysteine to polypeptides for synthesis of glutathione peroxidase mimics. Metallomics : integrated biometal science 20110701
Optogenetic photochemical control of designer K+ channels in mammalian neurons. Journal of neurophysiology 20110701
Lanthanide-based time-resolved luminescence immunoassays. Analytical and bioanalytical chemistry 20110701
Nitrosative damage to free and zinc-bound cysteine thiols underlies nitric oxide toxicity in wild-type Borrelia burgdorferi. Molecular microbiology 20110701
Quantification of cysteinyl S-nitrosylation by fluorescence in unbiased proteomic studies. Biochemistry 20110628
Direct synthesis of biodegradable polysaccharide derivative hydrogels through aqueous Diels-Alder chemistry. Macromolecular rapid communications 20110616
A biochemical analysis of the constraints of tail-anchored protein biogenesis. The Biochemical journal 20110615
Linking of sensor molecules with amino groups to amino-functionalized AFM tips. Bioconjugate chemistry 20110615
DOTA derivatives for site-specific biomolecule-modification via click chemistry: synthesis and comparison of reaction characteristics. Bioorganic & medicinal chemistry 20110615
Solvent effect and time-dependent behavior of C-terminus-cysteine-modified cecropin P1 chemically immobilized on a polymer surface. Langmuir : the ACS journal of surfaces and colloids 20110607
Aptamer-conjugated nanobubbles for targeted ultrasound molecular imaging. Langmuir : the ACS journal of surfaces and colloids 20110607
A prospective study to assess the predictive value for hereditary spherocytosis using five laboratory tests (cryohemolysis test, eosin-5'-maleimide flow cytometry, osmotic fragility test, autohemolysis test, and SDS-PAGE) on 50 hereditary spherocytosis families in Argentina. Annals of hematology 20110601
Leucine-rich α-2-glycoprotein is a marker for idiopathic normal pressure hydrocephalus. Acta neurochirurgica 20110601
Toward self-adjuvanting subunit vaccines: model peptide and protein antigens incorporating covalently bound toll-like receptor-7 agonistic imidazoquinolines. Bioorganic & medicinal chemistry letters 20110601
3,4-Bis[4-(4-meth-oxy-phen-oxy)phen-yl]-2,5-dihydro-furan-2,5-dione. Acta crystallographica. Section E, Structure reports online 20110601
2-{2-[2-(1,3-Dioxoisoindol-2-yl)eth-oxy]eth-yl}isoindole-1,3-dione. Acta crystallographica. Section E, Structure reports online 20110601
siRNA nanocarriers based on methacrylic acid copolymers. Journal of controlled release : official journal of the Controlled Release Society 20110530
Tunable reagents for multi-functional bioconjugation: reversible or permanent chemical modification of proteins and peptides by control of maleimide hydrolysis. Chemical communications (Cambridge, England) 20110521
Highly selective fluorescent OFF-ON thiol probes based on dyads of BODIPY and potent intramolecular electron sink 2,4-dinitrobenzenesulfonyl subunits. Organic & biomolecular chemistry 20110521
Evaluation of a maleimido derivative of NOTA for site-specific labeling of affibody molecules. Bioconjugate chemistry 20110518
Facile method of constructing polyproteins for single-molecule force spectroscopy studies. Langmuir : the ACS journal of surfaces and colloids 20110517
Mechanically facilitated retro [4+2] cycloadditions. Journal of the American Chemical Society 20110511
Development of methods for the synthesis of libraries of substituted maleimides and α,β-unsaturated-γ-butyrolactams. The Journal of organic chemistry 20110506
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Rapid evaluation of Antrodia camphorata natural products and derivatives in tumourigenic liver progenitor cells with a novel cell proliferation assay. ChemMedChem 20091001
Urea-induced unfolding of Na,K-ATPase as evaluated by electron paramagnetic resonance spectroscopy. Biochemistry 20090929
Practical synthesis of maleimides and coumarin-linked probes for protein and antibody labelling via reduction of native disulfides. Organic & biomolecular chemistry 20090907
Characterisation of the passive permeability barrier of nuclear pore complexes. The EMBO journal 20090902
Characterization of highly stable liposomal and immunoliposomal formulations of vincristine and vinblastine. Cancer chemotherapy and pharmacology 20090901
Nanoscale presentation of cell adhesive molecules via block copolymer self-assembly. Biomaterials 20090901
Structure-reactivity relationships in a recognition mediated [3+2] dipolar cycloaddition reaction. Organic & biomolecular chemistry 20090821
Hydrogels cross-linked by native chemical ligation. Biomacromolecules 20090810
Mechanical and kinetic effects of shortened tropomyosin reconstituted into myofibrils. Pflugers Archiv : European journal of physiology 20090801
eta(1)-N-succinimidato complexes of iron, molybdenum and tungsten as reversible inhibitors of papain. Journal of inorganic biochemistry 20090801
Farinomalein, a maleimide-bearing compound from the entomopathogenic fungus Paecilomyces farinosus. Journal of natural products 20090801
Control of the molecular orientation of membrane-anchored biomimetic glycopolymers. Journal of the American Chemical Society 20090729
Theoretical study of photophysical properties of bisindolylmaleimide derivatives. The journal of physical chemistry. A 20090723
Development of enzymatically cleavable prodrugs derived from dendritic polyglycerol. Bioorganic & medicinal chemistry letters 20090715
Synthesis of semitelechelic maleimide poly(PEGA) for protein conjugation by RAFT polymerization. Biomacromolecules 20090713
From synthesis to biologics: preclinical data on a chemistry derived anticancer vaccine. Journal of the American Chemical Society 20090708
Fluorescent tumour imaging of type I IGF receptor in vivo: comparison of antibody-conjugated quantum dots and small-molecule fluorophore. British journal of cancer 20090707
In vitro and in vivo study of an albumin-binding prodrug of doxorubicin that is cleaved by cathepsin B. Cancer chemotherapy and pharmacology 20090701
Radiosynthesis of new [90Y]-DOTA-based maleimide reagents suitable for the prelabeling of thiol-bearing L-oligonucleotides and peptides. Bioconjugate chemistry 20090701
Temperature-induced intracellular uptake of thermoresponsive polymeric micelles. Biomacromolecules 20090608
Targeting of epidermal growth factor receptor (EGFR)-expressing tumor cells with sterically stabilized affibody liposomes (SAL). Bioconjugate chemistry 20090601
Tailored PEG for rh-G-CSF analogue site-specific conjugation. Bioconjugate chemistry 20090601
Integrin alphaVbeta3 targeted gene delivery using RGD peptidomimetic conjugates with copolymers of PEGylated poly(ethylene imine). Bioconjugate chemistry 20090601
End-functionalized polymers and junction-functionalized diblock copolymers via RAFT chain extension with maleimido monomers. Bioconjugate chemistry 20090601
Clinico-hematological profile of hereditary spherocytosis: experience from a tertiary care center in North India. Hematology (Amsterdam, Netherlands) 20090601
The glycosylphosphatidylinositol-PLC in Trypanosoma brucei forms a linear array on the exterior of the flagellar membrane before and after activation. PLoS pathogens 20090601
1-Methoxycarbonylpyrrolizin-3-one and related compounds. Organic & biomolecular chemistry 20090521
Acyl chloride-modified amorphous carbon substrates for the attachment of alcohol-, thiol-, and amine-containing molecules. Langmuir : the ACS journal of surfaces and colloids 20090505
Serologic assay to quantify human immunoglobulin G antibodies to the Staphylococcus aureus iron surface determinant B antigen. Clinical and vaccine immunology : CVI 20090501
Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells. PLoS biology 20090501
Oxidation of the alarmin high-mobility group box 1 protein (HMGB1) during apoptosis. Autoimmunity 20090501
Rapid flow cytometric test using eosin-5-maleimide for diagnosis of red blood cell membrane disorders. The Southeast Asian journal of tropical medicine and public health 20090501
3-(6-Benz-yloxy-2,2-dimethyl-perhydro-furo[2,3-d][1,3]dioxol-5-yl)-5-(4-bromo-phen-yl)-2-phenyl-perhydro-pyrrolo[3,4-d]isoxazole-4,6-dione. Acta crystallographica. Section E, Structure reports online 20090501
Energetic analyses of chair and boat conformations of maleimide substituted cyclohexane derivatives. Journal of computational chemistry 20090430
Inhibition of monoamine oxidase B by N-methyl-2-phenylmaleimides. Bioorganic & medicinal chemistry 20090415
RAFT-generated polyacrylamide-DNA block copolymers for single-nucleotide polymorphism genotyping by affinity capillary electrophoresis. Biomacromolecules 20090413
Improvement of metal and tissue adhesion on surface-modified parylene C. Journal of biomedical materials research. Part A 20090401
Simple and convenient radiolabeling of proteins using a prelabeling-approach with thiol-DOTA. Bioorganic & medicinal chemistry letters 20090401
The trefoil factor interacting protein TFIZ1 binds the trefoil protein TFF1 preferentially in normal gastric mucosal cells but the co-expression of these proteins is deregulated in gastric cancer. The international journal of biochemistry & cell biology 20090301
Enhanced antibody responses to Plasmodium falciparum Pfs28 induced in mice by conjugation to ExoProtein A of Pseudomonas aeruginosa with an improved procedure. Microbes and infection 20090301
Production of heparin-containing hydrogels for modulating cell responses. Acta biomaterialia 20090301
RNA-dependent oligomerization of APOBEC3G is required for restriction of HIV-1. PLoS pathogens 20090301
Strategies for blocking the fibrogenic actions of connective tissue growth factor (CCN2): From pharmacological inhibition in vitro to targeted siRNA therapy in vivo. Journal of cell communication and signaling 20090301
Lactoferrin-conjugated PEG-PLA nanoparticles with improved brain delivery: in vitro and in vivo evaluations. Journal of controlled release : official journal of the Controlled Release Society 20090220
Photochromic bis(thiophen-3-yl)maleimides studied with time-resolved spectroscopy. The journal of physical chemistry. A 20090212
Simple ortho- and para-hydroquinones as compounds neuroprotective against oxidative stress in a manner associated with specific transcriptional activation. Biochemical and biophysical research communications 20090206
Selective spectrofluorimetric determination of glutathione in clinical and biological samples using 1,3,5,7-tetramethyl-8-phenyl-(2-maleimide)-difluoroboradiaza-s-indacene. Analytica chimica acta 20090202
Glycogen synthase kinase-3 inhibition by 3-anilino-4-phenylmaleimides: insights from 3D-QSAR and docking. Journal of computer-aided molecular design 20090201
Structural insights into the inhibited states of the Mer receptor tyrosine kinase. Journal of structural biology 20090201
Development of dual-acting prodrugs for circumventing multidrug resistance. Bioorganic & medicinal chemistry letters 20090201
Conformational analysis of trimeric maleimide substituted 1,5,9-triazacyclododecane HIV fusion scaffolds. Bioorganic & medicinal chemistry 20090201
Development of protein-binding bifunctional linkers for a new generation of dual-acting prodrugs. Bioconjugate chemistry 20090201
The mutant erythrocyte band 3 protein in Southeast Asian ovalocytosis does not bind eosin-5-maleimide. International journal of laboratory hematology 20090201
New theophylline-activated Diels-Alderase ribozymes by molecular engineering. Organic & biomolecular chemistry 20090121
Positioning multiple proteins at the nanoscale with electron beam cross-linked functional polymers. Journal of the American Chemical Society 20090121
Maleimide immobilized on a PE surface: preparation, characterization and application as a free-radical photoinitiator. Langmuir : the ACS journal of surfaces and colloids 20090120
Characterization of poly(ethylene glycol) and PEGylated products by LC/MS with postcolumn addition of amines. Analytical chemistry 20090115
Targeted Paclitaxel by conjugation to iron oxide and gold nanoparticles. Journal of the American Chemical Society 20090114
Targeted antimicrobial activity of a specific IgG-SMAP28 conjugate against Porphyromonas gingivalis in a mixed culture. International journal of antimicrobial agents 20090101
Maleimide conjugation markedly enhances the immunogenicity of both human and murine idiotype-KLH vaccines. Molecular immunology 20090101
Dual fluorescent labeling method to visualize plasmid DNA degradation. Bioconjugate chemistry 20090101
Hemoglobin conjugated with a Band 3 N-terminus derived peptide as an oxygen carrier. Artificial cells, blood substitutes, and immobilization biotechnology 20090101
The influence of catalysis on mad2 activation dynamics. PLoS biology 20090101
Molecular models of human P-glycoprotein in two different catalytic states. BMC structural biology 20090101
Conformational analysis (geometry optimization) of nucleosidic antitumor antibiotic showdomycin by Arguslab 4 software. Pakistan journal of pharmaceutical sciences 20090101
The p53-induced Siva-1 plays a significant role in cisplatin-mediated apoptosis. Journal of carcinogenesis 20090101
Dissection of kinesin's processivity. PloS one 20090101
Surface plasmon resonance imaging of cells and surface-associated fibronectin. BMC cell biology 20090101
First higher-order photocycloaddition to a C=N bond: 1,3-diazepines from maleimides. Angewandte Chemie (International ed. in English) 20090101
Anti-idiotypic antibodies: a new approach in prion research. BMC immunology 20090101
Loss of metal ions, disulfide reduction and mutations related to familial ALS promote formation of amyloid-like aggregates from superoxide dismutase. PloS one 20090101
Mass spectrometry assisted lithography for the patterning of cell adhesion ligands on self-assembled monolayers. Angewandte Chemie (International ed. in English) 20090101
Two-stimuli manipulation of a biological motor. Journal of nanobiotechnology 20090101
Bioinformatic analysis of xenobiotic reactive metabolite target proteins and their interacting partners. BMC chemical biology 20090101
Differential effects of iodoacetamide and iodoacetate on glycolysis and glutathione metabolism of cultured astrocytes. Frontiers in neuroenergetics 20090101
Illuminating the life of GPCRs. Cell communication and signaling : CCS 20090101
Adhesion molecule-modified biomaterials for neural tissue engineering. Frontiers in neuroengineering 20090101
Characterization for binding complex formation with site-directly immobilized antibodies enhancing detection capability of cardiac troponin I. Journal of biomedicine & biotechnology 20090101
Ocular delivery of compacted DNA-nanoparticles does not elicit toxicity in the mouse retina. PloS one 20090101
Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor. PloS one 20090101
p53 Amino-terminus region (1-125) stabilizes and restores heat denatured p53 wild phenotype. PloS one 20090101
[New derivatives of azobenzene for the directed modification of proteins]. Bioorganicheskaia khimiia 20090101
Modulation of cell surface protein free thiols: a potential novel mechanism of action of the sesquiterpene lactone parthenolide. PloS one 20090101
Protein C-terminal labeling and biotinylation using synthetic peptide and split-intein. PloS one 20090101
Real-time imaging and quantification of amyloid-beta peptide aggregates by novel quantum-dot nanoprobes. PloS one 20090101
A biomimetic approach for the creation of two-dimensional microscale surface patterns: creation of isolated immunological synapses. International journal of biomaterials 20090101
[Evaluation of hepatotoxicity of novel maleimide derivative with cytostatic activity and its effect on peroxidation process and antioxidant system in the liver]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20090101
N-[4-(Prop-2-yn-yloxy)phen-yl]maleimide. Acta crystallographica. Section E, Structure reports online 20090101
Synthesis and Characterization of Anti-HER2 Antibody Conjugated CdSe/CdZnS Quantum Dots for Fluorescence Imaging of Breast Cancer Cells. Sensors (Basel, Switzerland) 20090101
DNA sensors with diamond as a promising alternative transducer material. Sensors (Basel, Switzerland) 20090101
Search for inhibitors of bacterial and human protein kinases among derivatives of diazepines[1,4] annelated with maleimide and indole cycles. Journal of medicinal chemistry 20081225
A method for the reversible trapping of proteins in non-native conformations. Biochemistry 20081223
Albumin-conjugated C34 peptide HIV-1 fusion inhibitor: equipotent to C34 and T-20 in vitro with sustained activity in SCID-hu Thy/Liv mice. The Journal of biological chemistry 20081205
Molecular bases for the recognition of short peptide substrates and cysteine-directed modifications of human insulin-degrading enzyme. Biochemistry 20081202
Structural and thermal characterizations of silica nanoparticles grafted with pendant maleimide and epoxide groups. Journal of colloid and interface science 20081201
HER-2-targeted nanoparticle-affibody bioconjugates for cancer therapy. ChemMedChem 20081201
Enhancement of electrochemical signal on gold electrodes by polyvalent esterase-dendrimer clusters. Bioconjugate chemistry 20081201
Sites of modification of hemospan, a poly(ethylene glycol)-modified human hemoglobin for use as an oxygen therapeutic. Bioconjugate chemistry 20081119
Low reduction potential of Ero1alpha regulatory disulphides ensures tight control of substrate oxidation. The EMBO journal 20081119
Role of the domain encompassing Arg304-Ile328 in rat P2X2 receptor conformation revealed by alterations in complex glycosylation at Asn298. The Biochemical journal 20081115
Antibody conjugates of 7-ethyl-10-hydroxycamptothecin (SN-38) for targeted cancer chemotherapy. Journal of medicinal chemistry 20081113
Design of quantum dot-conjugated lipids for long-term, high-speed tracking experiments on cell surfaces. Journal of the American Chemical Society 20081112
Theoretical calculations of the molecular properties of maleimide and its dimer. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081101
Selective fluorescent labeling of S-nitrosothiols (S-FLOS): a novel method for studying S-nitrosation. Nitric oxide : biology and chemistry 20081101
Photosynthetic electron flow affects H2O2 signaling by inactivation of catalase in Chlamydomonas reinhardtii. Planta 20081101
S-nitrosylation of surfactant protein-D controls inflammatory function. PLoS biology 20081101
1,1,3-Trimethyl-3-(4-nitro-phen-yl)indane. Acta crystallographica. Section E, Structure reports online 20081101
Organic-inorganic nanohybrids via directly grafting gold nanoparticles onto conjugated copolymers through the Diels-Alder reaction. Langmuir : the ACS journal of surfaces and colloids 20081021
Toward a prostate specific antigen-based prostate cancer diagnostic assay: preparation of keyhole limpet hemocyanin-conjugated normal and transformed prostate specific antigen fragments. Journal of the American Chemical Society 20081015
Autoxidation of the site-specifically PEGylated hemoglobins: role of the PEG chains and the sites of PEGylation in the autoxidation. Biochemistry 20081014
Effect of hepatocyte growth factor encapsulated in targeted liposomes on liver cirrhosis. Journal of controlled release : official journal of the Controlled Release Society 20081006
Combination chemotherapy and photodynamic therapy with fab' fragment targeted HPMA copolymer conjugates in human ovarian carcinoma cells. Molecular pharmaceutics 20081006
Preparation of poly(ethylene glycol) protected nanoparticles with variable bioconjugate ligand density. Biomacromolecules 20081001
Expression of Xhdsi-1VOC, a novel member of the vicinal oxygen chelate (VOC) metalloenzyme superfamily, is up-regulated in leaves and roots during desiccation in the resurrection plant Xerophyta humilis (Bak) Dur and Schinz. Journal of experimental botany 20081001
N-(4-Chloro-phen-yl)maleimide. Acta crystallographica. Section E, Structure reports online 20081001
Probing conformational changes of prestin with thiol-reactive optical switches. Biophysical journal 20080915
Topological properties of the triple gene block protein 2 of Bamboo mosaic virus. Virology 20080915
Sulfhydryl-based tumor antigen-carrier protein conjugates stimulate superior antitumor immunity against B cell lymphomas. Journal of immunology (Baltimore, Md. : 1950) 20080915
A protecting group free synthesis of (+/-)-neostenine via the [5 + 2] photocycloaddition of maleimides. The Journal of organic chemistry 20080905
Facile construction of sulfanyl-terminated poly(ethylene glycol)-brushed layer on a gold surface for protein immobilization by the combined use of sulfanyl-ended telechelic and semitelechelic poly(ethylene glycol)s. Langmuir : the ACS journal of surfaces and colloids 20080902
Peptide-grafted nanodiamonds: preparation, cytotoxicity and uptake in cells. Chembiochem : a European journal of chemical biology 20080901
Mechanism of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy)-mediated mitochondrial dysfunction in rat liver. Proteomics 20080901
A generic expression system to produce proteins that co-assemble with alkane thiol SAM. International journal of nanomedicine 20080901
Two structurally distinct inhibitors of glycogen synthase kinase 3 induced centromere positive micronuclei in human lymphoblastoid TK6 cells. Mutation research 20080825
Covalent inhibitors of human monoacylglycerol lipase: ligand-assisted characterization of the catalytic site by mass spectrometry and mutational analysis. Chemistry & biology 20080825
Site-specific labeling of annexin V with F-18 for apoptosis imaging. Bioconjugate chemistry 20080820
Evaluation of a maleimido derivative of CHX-A'' DTPA for site-specific labeling of affibody molecules. Bioconjugate chemistry 20080801
Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries. Natural product reports 20080801
Serial protein labeling with infrared maleimide dyes to identify cysteine modifications. Journal of proteomics 20080721
Design, synthesis, and biological evaluation of novel 3-aryl-4-(1H-indole-3yl)-1,5-dihydro-2H-pyrrole-2-ones as vascular endothelial growth factor receptor (VEGF-R) inhibitors. Journal of medicinal chemistry 20080710
Immobilization of urokinase on the islet surface by amphiphilic poly(vinyl alcohol) that carries alkyl side chains. Biomaterials 20080701
Recombinant aequorin with a reactive cysteine residue for conjugation with maleimide-activated antibody. Analytical biochemistry 20080701
Towards a target label-free suboptimum oligonucleotide displacement-based detection system. Analytical and bioanalytical chemistry 20080701
Using the eosin-5-maleimide binding test in the differential diagnosis of hereditary spherocytosis and hereditary pyropoikilocytosis. Cytometry. Part B, Clinical cytometry 20080701
Cardiac peroxiredoxins undergo complex modifications during cardiac oxidant stress. American journal of physiology. Heart and circulatory physiology 20080701
Maleimide and maleic anhydride derivatives from the mycelia of Antrodia cinnamomea and their nitric oxide inhibitory activities in macrophages. Journal of natural products 20080701
In situ synthesis of lipopeptides as versatile receptors for the specific binding of nanoparticles and liposomes to solid-supported membranes. Small (Weinheim an der Bergstrasse, Germany) 20080701
In vitro and in vivo evaluation of doxorubicin conjugates with the divalent peptide E-[c(RGDfK)2] that targets integrin alphavbeta3. Bioconjugate chemistry 20080701
Segment block dendrimers via Diels-Alder cycloaddition. Organic letters 20080619
Cy5 labeled antimicrobial peptides for enhanced detection of Escherichia coli O157:H7. Biosensors & bioelectronics 20080615
The activity of HDAC8 depends on local and distal sequences of its peptide substrates. Biochemistry 20080610
Immobilized chemoattractant peptides mediate adhesion and distinct calcium-dependent cell signaling in human neutrophils. Langmuir : the ACS journal of surfaces and colloids 20080601
One-pot synthesis and characterization of three kinds of thiol-organosilica nanoparticles. Langmuir : the ACS journal of surfaces and colloids 20080506
Novel 5-azaindolocarbazoles as cytotoxic agents and Chk1 inhibitors. Bioorganic & medicinal chemistry 20080501
Measurement of protein sulfhydryls in response to cellular oxidative stress using gel electrophoresis and multiplexed fluorescent imaging analysis. Chemical research in toxicology 20080501
N-(3-Chloro-phen-yl)maleimide. Acta crystallographica. Section E, Structure reports online 20080501
Effect of chirality on pi-stacking in styrene and maleimide alternating copolymers. The journal of physical chemistry. B 20080424
A novel bifunctional maleimido CHX-A'' chelator for conjugation to thiol-containing biomolecules. Bioorganic & medicinal chemistry letters 20080415
Bifunctional ligands based on the DOTA-monoamide cage. Organic & biomolecular chemistry 20080407
Anthracene cycloadducts as highly selective chiral auxiliaries. The Journal of organic chemistry 20080404
The cardio-protecting agent and topoisomerase II catalytic inhibitor sobuzoxane enhances doxorubicin-DNA adduct mediated cytotoxicity. Cancer chemotherapy and pharmacology 20080401
Aryl-indolyl maleimides as inhibitors of CaMKIIdelta. Part 1: SAR of the aryl region. Bioorganic & medicinal chemistry letters 20080401
Characterization of local polarity and structure of Cys121 domain in beta-lactoglobulin with a new thiol-specific fluorescent probe. The Analyst 20080401
Multivalency of Sonic hedgehog conjugated to linear polymer chains modulates protein potency. Bioconjugate chemistry 20080401
Cytosolic region of TM6 in P-glycoprotein: topographical analysis and functional perturbation by site directed labeling. Biochemistry 20080325
Rapid identification of reactive cysteine residues for site-specific labeling of antibody-Fabs. Journal of immunological methods 20080320
Analysis of functionalization of methoxy-PEG as maleimide-PEG. Analytical biochemistry 20080315
Saturation fluorescence labeling of proteins for proteomic analyses. Analytical biochemistry 20080315
DNA and RNA can be equally efficient catalysts for carbon-carbon bond formation. Journal of the American Chemical Society 20080312
Maleimide-activated aryl diazonium salts for electrode surface functionalization with biological and redox-active molecules. Langmuir : the ACS journal of surfaces and colloids 20080304
Systematic Cys mutagenesis of FlgI, the flagellar P-ring component of Escherichia coli. Microbiology (Reading, England) 20080301
Functionally important conserved length of C-terminal regions of yeast and bovine ADP/ATP carriers, identified by deletion mutants studies, and water accessibility of the amino acids at the C-terminal region of the yeast carrier. Mitochondrion 20080301
Contribution of linker stability to the activities of anticancer immunoconjugates. Bioconjugate chemistry 20080301
1-Phenyl-4-(triphenyl-phosphanyl-idene)pyrrolidine-2,3,5-trione. Acta crystallographica. Section E, Structure reports online 20080301
Usefulness of the eosin-5'-maleimide cytometric method as a first-line screening test for the diagnosis of hereditary spherocytosis: comparison with ektacytometry and protein electrophoresis. British journal of haematology 20080201
Development of multivalent radioimmunonanoparticles for cancer imaging and therapy. Cancer biotherapy & radiopharmaceuticals 20080201
PEGylation of cyanovirin-N, an entry inhibitor of HIV. Advanced drug delivery reviews 20080103
Synthesis of 4-aminotropones from [(sulfinyl or sulfonyl)methyl]-substituted p-quinamines. Chemistry (Weinheim an der Bergstrasse, Germany) 20080101
In vivo reduction-oxidation state of protein disulfide isomerase: the two active sites independently occur in the reduced and oxidized forms. Antioxidants & redox signaling 20080101
N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids. Bioorganic & medicinal chemistry 20080101
Use of multiple carboxylates to increase intracellular retention of fluorescent probes following release from cell penetrating fluorogenic conjugates. Bioconjugate chemistry 20080101
Porphyrinmaleimides: towards thiol probes for cysteine residues in proteins. Bioconjugate chemistry 20080101
[18F]FBEM-Z(HER2:342)-Affibody molecule-a new molecular tracer for in vivo monitoring of HER2 expression by positron emission tomography. European journal of nuclear medicine and molecular imaging 20080101
Evaluation of maleimide derivative of DOTA for site-specific labeling of recombinant affibody molecules. Bioconjugate chemistry 20080101
Evaluation of the transfection property of a peptide ligand for the fibroblast growth factor receptor as part of PEGylated polyethylenimine polyplex. Journal of drug targeting 20080101
Assaying protein palmitoylation in plants. Plant methods 20080101
Cowpea mosaic virus capsid: a promising carrier for the development of carbohydrate based antitumor vaccines. Chemistry (Weinheim an der Bergstrasse, Germany) 20080101
Lipoperoxidation and protein oxidative damage exhibit different kinetics during septic shock. Mediators of inflammation 20080101
The effect of N-ethylmaleimide on permeability transition as induced by carboxyatractyloside, agaric acid, and oleate. Cell biochemistry and biophysics 20080101
Characterization of the long-terminal repeat single-strand tail-binding site of Moloney-MuLV integrase by crosslinking. Biological research 20080101
Capillary electrophoresis for the characterization of quantum dots after non-selective or selective bioconjugation with antibodies for immunoassay. Journal of nanobiotechnology 20080101
Development of a library of N-substituted maleimides for the local functionalization of linear polymer chains. Chemistry (Weinheim an der Bergstrasse, Germany) 20080101
The imaging probe development center and the production of molecular imaging probes. Current chemical genomics 20080101
Effects of 1,8-cineole on the dynamics of lipids and proteins of stratum corneum. International journal of pharmaceutics 20071210
Active tumor-targeted delivery of PEG-protein via transferrin-transferrin-receptor system. Journal of drug targeting 20071201
Effect of maleimide-polyethylene glycol hemoglobin (MP4) on hemodynamics and acid-base status after uncontrolled hemorrhage in anesthetized swine: comparison with crystalloid and blood. The Journal of trauma 20071201
Receptor-induced thiolate couples Env activation to retrovirus fusion and infection. PLoS pathogens 20071201
Catalysis of imido group hydrolysis in a maleimide conjugate. Bioorganic & medicinal chemistry letters 20071115
Synthesis and properties of dendrimers possessing the same fluorophore(s) located either peripherally or off-center. The Journal of organic chemistry 20071109
Islet-encapsulation in ultra-thin layer-by-layer membranes of poly(vinyl alcohol) anchored to poly(ethylene glycol)-lipids in the cell membrane. Biomaterials 20071101
Design of targeted lipid nanocapsules by conjugation of whole antibodies and antibody Fab' fragments. Biomaterials 20071101
Anti-parallel membrane topology of a homo-dimeric multidrug transporter, EmrE. Journal of biochemistry 20071101
Immobilization of oligonucleotides on glass surface using an efficient heterobifunctional reagent through maleimide-thiol combination chemistry. Analytical biochemistry 20071015
Production of heparin-functionalized hydrogels for the development of responsive and controlled growth factor delivery systems. Journal of controlled release : official journal of the Controlled Release Society 20071008
Convergent preparation and photophysical characterization of dimaleimide dansyl fluorogens: elucidation of the maleimide fluorescence quenching mechanism. Journal of the American Chemical Society 20071003
Force-induced unfolding of fibronectin in the extracellular matrix of living cells. PLoS biology 20071001
Simultaneous LC/MS/MS determination of thiols and disulfides in urine samples based on differential labeling with ferrocene-based maleimides. Analytical chemistry 20070915
Ergosterimide, a new natural Diels-Alder adduct of a steroid and maleimide in the fungus Aspergillus niger. Steroids 20070901
Synthesis and characterization of novel thiol-reactive poly(ethylene glycol) cross-linkers for extracellular-matrix-mimetic biomaterials. Biomacromolecules 20070901
Mapping the electrostatic potential within the ribosomal exit tunnel. Journal of molecular biology 20070831
Synthesis and conformational analysis of novel trimeric maleimide cross-linking reagents. The Journal of organic chemistry 20070831
Bisindolylmaleimides with large Stokes shift and long-lasting chemiluminescence properties. Organic letters 20070830
Evidence for an interaction between the SH3 domain and the N-terminal extension of the essential light chain in class II myosins. Journal of molecular biology 20070824
A chelation-assisted transformation: synthesis of maleimides by the Rh-catalyzed carbonylation of alkynes with pyridin-2-ylmethylamine. The Journal of organic chemistry 20070817
A thiol-reactive fluorescence probe based on donor-excited photoinduced electron transfer: key role of ortho substitution. Organic letters 20070816
Investigation on PEGylation strategy of recombinant human interleukin-1 receptor antagonist. Bioorganic & medicinal chemistry 20070815
Cyclic Arg-Gly-Asp peptide-labeled liposomes for targeting drug therapy of hepatic fibrosis in rats. The Journal of pharmacology and experimental therapeutics 20070801
Dual control of cardiac Na+ Ca2+ exchange by PIP(2): analysis of the surface membrane fraction by extracellular cysteine PEGylation. The Journal of physiology 20070801
Studies of bioactivity, conformation and pharmacokinetic profiles of site-specific PEGylated thymosin alpha 1 derivatives. Drug metabolism letters 20070801
Preparation and evaluation of paclitaxel-loaded PEGylated immunoliposome. Journal of controlled release : official journal of the Controlled Release Society 20070731
Toward improved syntheses of dendrimer-based magnetic resonance imaging contrast agents: new bifunctional diethylenetriaminepentaacetic acid ligands and nonaqueous conjugation chemistry. Journal of medicinal chemistry 20070712
The phosphoinositide-specific phospholipase C inhibitor U73122 (1-(6-((17beta-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione) spontaneously forms conjugates with common components of cell culture medium. Drug metabolism and disposition: the biological fate of chemicals 20070701
N-(3-Triethoxysilylpropyl)-4-(N'-maleimidylmethyl)cyclohexanamide (TPMC): a heterobifunctional reagent for immobilization of oligonucleotides on glass surface. Bioorganic & medicinal chemistry letters 20070701
Radiolabeling of multimeric neurotensin(8-13) analogs with the short-lived positron emitter fluorine-18. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20070701
Synthesis and anti-HIV activity of trivalent CD4-mimetic miniproteins. Bioorganic & medicinal chemistry 20070615
Structure and DNA hybridization properties of mixed nucleic acid/maleimide-ethylene glycol monolayers. Analytical chemistry 20070615
Site-directed biotinylation of antibodies for controlled immobilization on solid surfaces. Analytical biochemistry 20070601
Toxicity and hemodynamic effects after single dose administration of MalPEG-hemoglobin (MP4) in rhesus monkeys. Translational research : the journal of laboratory and clinical medicine 20070601
Antifungal activity evaluation of the constituents of Haliclona baeri and Haliclona cymaeformis, collected from the Gulf of Thailand. Marine drugs 20070601
Toward an understanding of the acceleration of Diels-Alder reactions by a pseudo-intramolecular process achieved by molecular recognition. A DFT study. The Journal of organic chemistry 20070525
Novel bis(indolyl)maleimide pyridinophanes that are potent, selective inhibitors of glycogen synthase kinase-3. Bioorganic & medicinal chemistry letters 20070515
Structure and function of transmembrane segment XII in osmosensor and osmoprotectant transporter ProP of Escherichia coli. Biochemistry 20070515
The interaction of cationic polymers and their bisphosphonate derivatives with hydroxyapatite. Macromolecular bioscience 20070510
Protein-resistant self-assembled monolayers on gold with latent aldehyde functions. Langmuir : the ACS journal of surfaces and colloids 20070508
Novel liposomal formulation for targeted gene delivery. Pharmaceutical research 20070501
Disruption of interdomain interactions via partial calcium occupancy of calmodulin. Biochemistry 20070417
Identification of the sites of deoxyhaemoglobin PEGylation. The Biochemical journal 20070401
3,4-Diethyl-2,5-dihydro-1H-pyrrole-2,5-dione. Acta crystallographica. Section C, Crystal structure communications 20070401
Evaluation of low energy CID and ECD fragmentation behavior of mono-oxidized thio-ether bonds in peptides. Journal of the American Society for Mass Spectrometry 20070301
Experimental test of connector rotation during DNA packaging into bacteriophage phi29 capsids. PLoS biology 20070301
Thermal degradation analysis of amino acids in fingerprint residue by pyrolysis GC-MS to develop new latent fingerprint developing reagents. Journal of forensic sciences 20070301
Development of sulfhydryl-reactive silica for protein immobilization in high-performance affinity chromatography. Analytical chemistry 20070215
Diels-Alder ribozyme catalysis: a computational approach. Journal of the American Chemical Society 20070131
A robust method for production of MHC tetramers with small molecule fluorophores. Journal of immunological methods 20070130
Site-specific labeling of DNA-protein conjugates by means of expressed protein ligation. Chemical communications (Cambridge, England) 20070128
Cysteine-specific, covalent anchoring of transition organometallic complexes to the protein papain from Carica papaya. Chembiochem : a European journal of chemical biology 20070122
Synthesis and evaluation of peptidic maleimides as transglutaminase inhibitors. Bioorganic & medicinal chemistry letters 20070115
Oriented immobilization of antibodies with GST-fused multiple Fc-specific B-domains on a gold surface. Analytical chemistry 20070115
Evidence of ball-and-chain transport of ferric enterobactin through FepA. The Journal of biological chemistry 20070105
Selective modification of surface-exposed thiol groups in Trigonopsis variabilis D-amino acid oxidase using poly(ethylene glycol) maleimide and its effect on activity and stability of the enzyme. Biotechnology and bioengineering 20070101
Influence of oil droplet surface charge on the performance of antibody--emulsion conjugates. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20070101
Peptide-nucleic acid-modified ion-sensitive field-effect transistor-based biosensor for direct detection of DNA hybridization. Analytical chemistry 20070101
Tumor cell targeting of transferrin-PEG-TNF-alpha conjugate via a receptor-mediated delivery system: design, synthesis, and biological evaluation. Bioconjugate chemistry 20070101
Stability of cell-penetrating peptide-morpholino oligomer conjugates in human serum and in cells. Bioconjugate chemistry 20070101
Convenient synthesis of maleimido-derivatized lanthanide(III) chelates and their use in mercapto group conjugation. Bioconjugate chemistry 20070101
Synthesis of enzyme-degradable, peptide-cross-linked dextran hydrogels. Bioconjugate chemistry 20070101
An acetal-based PEGylation reagent for pH-sensitive shielding of DNA polyplexes. Bioconjugate chemistry 20070101
Sensitization of spinal cord nociceptive neurons with a conjugate of substance P and cholera toxin. BMC neuroscience 20070101
Phospholipase C and myosin light chain kinase inhibition define a common step in actin regulation during cytokinesis. BMC cell biology 20070101
Optimization of three- and four-component reactions for polysubstituted piperidines: application to the synthesis and preliminary biological screening of a prototype library. Journal of combinatorial chemistry 20070101
Differential scanning calorimetry study of glycerinated rabbit psoas muscle fibres in intermediate state of ATP hydrolysis. BMC structural biology 20070101
Oxygen and redox sensing by two-component systems that regulate behavioral responses: behavioral assays and structural studies of aer using in vivo disulfide cross-linking. Methods in enzymology 20070101
Enhanced detection of thiol peptides by matrix-assisted laser desorption/ionization mass spectrometry after selective derivatization with a tailor-made quaternary ammonium tag containing maleimidyl group. Rapid communications in mass spectrometry : RCM 20070101
Construction of DNA microarray on glass surface using efficient heterobifunctional reagent. Nucleic acids symposium series (2004) 20070101
The reticulons: a family of proteins with diverse functions. Genome biology 20070101
Bio-nanopatterning of Surfaces. Nanoscale research letters 20070101
Quantitative analysis of protein co-localization on B cells opsonized with rituximab and complement using the ImageStream multispectral imaging flow cytometer. Journal of immunological methods 20061220
Synthesis and evaluation of peptidic irreversible inhibitors of tissue transglutaminase. Bioorganic & medicinal chemistry 20061215
A multicenter clinical study of the safety and activity of maleimide-polyethylene glycol-modified Hemoglobin (Hemospan) in patients undergoing major orthopedic surgery. Anesthesiology 20061201
On parallel and antiparallel topology of a homodimeric multidrug transporter. The Journal of biological chemistry 20061124
Controlling dispersion and migration of particulate additives with block copolymers and Diels-Alder chemistry. Langmuir : the ACS journal of surfaces and colloids 20061121
Probing the limits of rate acceleration mediated by hydrogen bonds. Organic letters 20061109
Light-induced depolarization of neurons using a modified Shaker K(+) channel and a molecular photoswitch. Journal of neurophysiology 20061101
Inactivation of oxidized and S-nitrosylated mitochondrial proteins in alcoholic fatty liver of rats. Hepatology (Baltimore, Md.) 20061101
cis-3,5-Cyclohexadiene-1,2-diol derivatives: facial selectivity in their Diels-Alder reactions with ethylenic, acetylenic and azo dienophiles. Organic & biomolecular chemistry 20061021
N-(3-Triethoxysilylpropyl)-6-(N-maleimido)-hexanamide: An efficient heterobifunctional reagent for the construction of oligonucleotide microarrays. Analytical biochemistry 20061015
The structure of the second cytosolic loop of the yeast mitochondrial ADP/ATP carrier AAC2 is dependent on the conformational state. Mitochondrion 20061001
Design and implementation of a highly selective minimal self-replicating system. Angewandte Chemie (International ed. in English) 20060925
Controlling a recognition-mediated reaction using a pH switch. Chemical communications (Cambridge, England) 20060921
Staurosporine and rebeccamycin aglycones are assembled by the oxidative action of StaP, StaC, and RebC on chromopyrrolic acid. Journal of the American Chemical Society 20060920
A generic building block for C- and N-terminal protein-labeling and protein-immobilization. Bioorganic & medicinal chemistry 20060915
Triple helix stabilization by covalently linked DNA-bisbenzimidazole conjugate synthesized by maleimide-thiol coupling chemistry. Bioorganic & medicinal chemistry 20060915
Severing of F-actin by yeast cofilin is pH-independent. Cell motility and the cytoskeleton 20060901
Potent inhibition of human telomerase by U-73122. Journal of biomedical science 20060901
Stealth liposomes: review of the basic science, rationale, and clinical applications, existing and potential. International journal of nanomedicine 20060901
Increased osteoblast adhesion on nanoparticulate crystalline hydroxyapatite functionalized with KRSR. International journal of nanomedicine 20060901
The chemiluminescence mechanism of 3,4-bis(3-indolyl)-1H-pyrrole-2,5-dione, and the characteristics of chemiluminescence developed in the reaction with CH(3)CNH(2)O(2)NaOH. Talanta 20060815
4-Phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione inhibitors of the checkpoint kinase Wee1. Structure-activity relationships for chromophore modification and phenyl ring substitution. Journal of medicinal chemistry 20060810
Diels-Alder ligation of peptides and proteins. Chemistry (Weinheim an der Bergstrasse, Germany) 20060807
Development of tumor targeting anti-MUC-1 multimer: effects of di-scFv unpaired cysteine location on PEGylation and tumor binding. Protein engineering, design & selection : PEDS 20060801
Binding and signaling of surface-immobilized reagentless fluorescent biosensors derived from periplasmic binding proteins. Protein science : a publication of the Protein Society 20060801
An engineered virus as a bright fluorescent tag and scaffold for cargo proteins--capture and transport by gliding microtubules. Journal of nanoscience and nanotechnology 20060801
Surface anchoring of a bacterial adhesin secreted by the two-partner secretion pathway. Molecular microbiology 20060701
A thiol-reactive 18F-labeling agent, N-[2-(4-18F-fluorobenzamido)ethyl]maleimide, and synthesis of RGD peptide-based tracer for PET imaging of alpha v beta 3 integrin expression. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20060701
A highly tunable family of chiral bisphospholanes for rh-catalyzed enantioselective hydrogenation reactions. Chemistry (Weinheim an der Bergstrasse, Germany) 20060623
Correlation of the acid-sensitivity of polyethylene glycol daunorubicin conjugates with their in vitro antiproliferative activity. Bioorganic & medicinal chemistry 20060615
Oriented immobilisation of engineered single-chain antibodies to develop biosensors for virus detection. Journal of virological methods 20060601
Lectin-conjugated PEG-PLA nanoparticles: preparation and brain delivery after intranasal administration. Biomaterials 20060601
Maleimide spacers as versatile linkers in the synthesis of bioconjugates of anthracyclines. Natural product reports 20060601
PM-20, a novel inhibitor of Cdc25A, induces extracellular signal-regulated kinase 1/2 phosphorylation and inhibits hepatocellular carcinoma growth in vitro and in vivo. Molecular cancer therapeutics 20060601
A deep, water-soluble cavitand acts as a phase-transfer catalyst for hydrophobic species. Angewandte Chemie (International ed. in English) 20060519
Nondisruptive, sequence-specific coupling of fluorochromes to plasmid DNA. Analytical biochemistry 20060515
Application of polymaleimidostyrene as a convenient immobilization reagent of enzyme in biosensor. Bioelectrochemistry (Amsterdam, Netherlands) 20060501
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Nuclear localizing sequences promote nuclear translocation and enhance the radiotoxicity of the anti-CD33 monoclonal antibody HuM195 labeled with 111In in human myeloid leukemia cells. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20060501
Fluorescent labeling of RAFT-generated poly(N-isopropylacrylamide) via a facile maleimide-thiol coupling reaction. Biomacromolecules 20060501
Fluorescent signal amplification of carbocyanine dyes using engineered viral nanoparticles. Journal of the American Chemical Society 20060419
A tumor vasculature targeted liposome delivery system for combretastatin A4: design, characterization, and in vitro evaluation. AAPS PharmSciTech 20060407
Silica-coated CdTe quantum dots functionalized with thiols for bioconjugation to IgG proteins. The journal of physical chemistry. B 20060323
A synthetic classic reinvented. Nature methods 20060201
Synthesis and biological evaluation of novel phenylcarbazoles as potential anticancer agents. Journal of medicinal chemistry 20060126
Role of transmembrane segment 10 in efflux mediated by the staphylococcal multidrug transport protein QacA. The Journal of biological chemistry 20060113
Structural optimization of a 'smart' doxorubicin-polypeptide conjugate for thermally targeted delivery to solid tumors. Journal of controlled release : official journal of the Controlled Release Society 20060110
Characterization of a monoclonal antibody with specificity for holo-transcobalamin. Nutrition & metabolism 20060101
Poly(ethylene glycol)-conjugated human serum albumin including iron porphyrins: surface modification improves the O2-transporting ability. Bioconjugate chemistry 20060101
Novel multi-component nanopharmaceuticals derived from poly(ethylene) glycol, retro-inverso-Tat nonapeptide and saquinavir demonstrate combined anti-HIV effects. AIDS research and therapy 20060101
Evaluation of cell-penetrating peptides (CPPs) as vehicles for intracellular delivery of antisense peptide nucleic acid (PNA). Bioconjugate chemistry 20060101
Molecular modeling studies of surface decoration of hemoglobin by maleimide PEG. Artificial cells, blood substitutes, and immobilization biotechnology 20060101
A new approach for DNA detection by SERRS. Faraday discussions 20060101
Liposome-based systems for anti-tumor vaccination: influence of lipopeptide adjuvants. Journal of liposome research 20060101
Flow cytometry as a diagnostic tool for hereditary spherocytosis. Acta haematologica 20060101
Effects of site-specific polyethylene glycol modification of recombinant human granulocyte colony-stimulating factor on its biologic activities. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20060101
Efficient non-viral ocular gene transfer with compacted DNA nanoparticles. PloS one 20060101
Probing the sequence of conformationally induced polarity changes in the molecular chaperonin GroEL with fluorescence spectroscopy. The journal of physical chemistry. B 20051229
Design and synthesis of site directed maleimide bifunctional chelators for technetium and rhenium. Dalton transactions (Cambridge, England : 2003) 20051221
Simulation of fluorescence anisotropy experiments: probing protein dynamics. Biophysical journal 20051201
The design and evaluation of a novel targeted drug delivery system using cationic emulsion-antibody conjugates. Journal of controlled release : official journal of the Controlled Release Society 20051128
SAR and 3D-QSAR studies on thiadiazolidinone derivatives: exploration of structural requirements for glycogen synthase kinase 3 inhibitors. Journal of medicinal chemistry 20051117
The active site His-460 of human acyl-coenzyme A:cholesterol acyltransferase 1 resides in a hitherto undisclosed transmembrane domain. The Journal of biological chemistry 20051111
In-plane enyne metathesis and subsequent Diels-Alder reactions on self-assembled monolayers. Langmuir : the ACS journal of surfaces and colloids 20051108
A mammalian actin substitution in yeast actin (H372R) causes a suppressible mitochondria/vacuole phenotype. The Journal of biological chemistry 20051028
Asymmetric indolylmaleimide derivatives and their complexation with zinc(II)-cyclen. The journal of physical chemistry. A 20051027
Cationic albumin-conjugated pegylated nanoparticles as novel drug carrier for brain delivery. Journal of controlled release : official journal of the Controlled Release Society 20051020
Surface reactions of 4-aminothiophenol with heterobifunctional crosslinkers bearing both succinimidyl ester and maleimide for biomolecular immobilization. Journal of colloid and interface science 20051001
Disulphide reaction staining for the identification of integumental elastic fibres. Archives of dermatological research 20051001
Enhancement of the therapeutic index: from nonmyeloablative and myeloablative toward pretargeted radioimmunotherapy for metastatic prostate cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 20051001
Development of albumin-binding doxorubicin prodrugs that are cleaved by prostate-specific antigen. Archiv der Pharmazie 20051001
Fourfold [2]rotaxanes based on calix[4]arenes. Journal of the American Chemical Society 20050928
Immobilization and hybridization of oligonucleotides on maleimido-terminated self-assembled monolayers. Analytical biochemistry 20050915
Alcoholic stem extract of Coscinium fenestratum regulates carbohydrate metabolism and improves antioxidant status in streptozotocin-nicotinamide induced diabetic rats. Evidence-based complementary and alternative medicine : eCAM 20050901
Siderophore transport through Escherichia coli outer membrane receptor FhuA with disulfide-tethered cork and barrel domains. The Journal of biological chemistry 20050826
Reactivation of mutant p53 and induction of apoptosis in human tumor cells by maleimide analogs. The Journal of biological chemistry 20050826
Comparison of the ATP binding sites of protein kinases using conformationally diverse bisindolylmaleimides. Journal of the American Chemical Society 20050824
An experimental and theoretical study of stereoselectivity of furan-maleic anhydride and furan-maleimide diels-alder reactions. The Journal of organic chemistry 20050805
Stereocontrolled synthesis of a complex library via elaboration of angular epoxyquinol scaffolds. The Journal of organic chemistry 20050805
Agaric acid induces mitochondrial permeability transition through its interaction with the adenine nucleotide translocase. Its dependence on membrane fluidity. Mitochondrion 20050801
Unexpected photophysical properties of symmetric indolylmaleimide derivatives. The journal of physical chemistry. A 20050728
Dual-targeted labeling of proteins using cysteine and selenomethionine residues. Analytical biochemistry 20050715
Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog. Endocrinology 20050701
Homogeneous assays for cellular proteases employing the platinum(II)-coproporphyrin label and time-resolved phosphorescence. Analytical biochemistry 20050701
Maleimido-terminated self-assembled monolayers. Chemistry (Weinheim an der Bergstrasse, Germany) 20050620
Hemoglobin-superoxide dismutase-chemical linkages that create a dual-function protein. Journal of the American Chemical Society 20050608
Combining microfluidic networks and peptide arrays for multi-enzyme assays. Journal of the American Chemical Society 20050525
Cationic albumin conjugated pegylated nanoparticle with its transcytosis ability and little toxicity against blood-brain barrier. International journal of pharmaceutics 20050513
Determination of WR-1065 in human blood by high-performance liquid chromatography following fluorescent derivatization by a maleimide reagent ThioGlo3. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050505
Nanopatterning of biomolecules with microscale beads. Chemphyschem : a European journal of chemical physics and physical chemistry 20050501
Alterations in band 3 protein and anion exchange in red blood cells of renal failure patients. Molecular and cellular biochemistry 20050501
Crosslinking of diene-modified DNA with bis-maleimides. Molecular bioSystems 20050501
Induction of effective and antigen-specific antitumour immunity by a liposomal ErbB2/HER2 peptide-based vaccination construct. British journal of cancer 20050425
Mercury impairment of mouse thymocyte survival in vitro: involvement of cellular thiols. Journal of toxicology and environmental health. Part A 20050409
Site directed maleimide bifunctional chelators for the M(CO)3+ core (M =(99m)Tc, Re). Chemical communications (Cambridge, England) 20050407
Effect of synthetic lipopeptides formulated in liposomes on the maturation of human dendritic cells. Molecular immunology 20050401
Development of simple thiol-reactive liposome formulations, one-step analysis and physicochemical characterization. The Journal of pharmacy and pharmacology 20050401
Design, synthesis and characterization of monomolecular interfacial layers. Bioelectrochemistry (Amsterdam, Netherlands) 20050401
Conjugation of multiple copies of polyethylene glycol to hemoglobin facilitated through thiolation: influence on hemoglobin structure and function. The protein journal 20050401
Design and synthesis of N-maleimido-functionalized hydrophilic polymers via copper-mediated living radical polymerization: a suitable alternative to PEGylation chemistry. Journal of the American Chemical Society 20050309
Optimized targeting of polyethylene glycol-stabilized anti-intercellular adhesion molecule 1 oligonucleotide/lipid particles to liver sinusoidal endothelial cells. Molecular pharmacology 20050301
Discovery of a novel N-iminylamidase activity: substrate specificity, chemicoselectivity and catalytic mechanism. Protein expression and purification 20050301
Diels-alder adducts of 3,6-dibromophencyclone with short-chain N-n-alkylmaleimides: 1H and 13C nuclear magnetic resonance studies of hindered rotations and magnetic anisotropy, and ab initio calculations for optimized structures. Applied spectroscopy 20050301
The development of potent and selective bisarylmaleimide GSK3 inhibitors. Bioorganic & medicinal chemistry letters 20050215
Accessibility of cysteines in the native bovine rod cGMP-gated channel. Biochemistry 20050208
Targeting of sterically stabilised pH-sensitive liposomes to human T-leukaemia cells. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20050201
Specific 3'-terminal modification of DNA with a novel nucleoside analogue that allows a covalent linkage of a nuclear localization signal and enhancement of DNA stability. Chembiochem : a European journal of chemical biology 20050201
A highly sensitive method for quantification of myosin light chain phosphorylation by capillary isoelectric focusing with laser-induced fluorescence detection. Electrophoresis 20050201
Synthesis and characterization of dimaleimide fluorogens designed for specific labeling of proteins. Journal of the American Chemical Society 20050119
Preparation of omega-functionalized eicosane-phosphate building blocks. Chemistry and physics of lipids 20050101
Characterization of site-specific ScFv PEGylation for tumor-targeting pharmaceuticals. Bioconjugate chemistry 20050101
A long-acting, highly potent interferon alpha-2 conjugate created using site-specific PEGylation. Bioconjugate chemistry 20050101
Lymphoid tissue targeting of anti-HIV drugs using liposomes. Methods in enzymology 20050101
A new maleimide-bound acid-cleavable solid-support reagent for profiling phosphorylation. Rapid communications in mass spectrometry : RCM 20050101
Thiolation of chitosan. Attachment of proteins via thioether formation. Biomacromolecules 20050101
Polyphenylene dendrimers as scaffolds for shape-persistent multiple peptide conjugates. Bioconjugate chemistry 20050101
1-[3-(2-[18F]fluoropyridin-3-yloxy)propyl]pyrrole-2,5-dione: design, synthesis, and radiosynthesis of a new [18F]fluoropyridine-based maleimide reagent for the labeling of peptides and proteins. Bioconjugate chemistry 20050101
PEGylated immunoliposomes directed against brain astrocytes. Drug delivery 20050101
Polysaccharide-poly(ethylene glycol) star copolymer as a scaffold for the production of bioactive hydrogels. Biomacromolecules 20050101
Synthesis and evaluation of insulin-human serum albumin conjugates. Bioconjugate chemistry 20050101
[Production and characteristics of PEGylated immunoliposome transport vectors specific for neural tissue astrocytes]. Biomeditsinskaia khimiia 20050101
Enhanced molecular volume of conservatively pegylated Hb: (SP-PEG5K)6-HbA is non-hypertensive. Artificial cells, blood substitutes, and immobilization biotechnology 20050101
Sulfhydryl-selective, covalent labeling of biomolecules with transition metallocarbonyl complexes. Synthesis of (eta5-C5H5)M(CO)3(eta1-N-maleimidato) (M = Mo, W), X-ray structure, and reactivity studies. Bioconjugate chemistry 20050101
Studies on the attachment of DNA to silica-coated nanoparticles through a Diels-Alder reaction. Nucleosides, nucleotides & nucleic acids 20050101
Tumor necrosis factor (TNF)-functionalized nanostructured particles for the stimulation of membrane TNF-specific cell responses. Bioconjugate chemistry 20050101
Chemical modification of cysteine residues is a misleading indicator of their status as active site residues in the vitamin K-dependent gamma-glutamyl carboxylation reaction. The Journal of biological chemistry 20041224
Self-replication vs. reactive binary complexes--manipulating recognition-mediated cycloadditions by simple structural modifications. Organic & biomolecular chemistry 20041207
Twisting of the second transmembrane alpha-helix of the mitochondrial ADP/ATP carrier during the transition between two carrier conformational states. Biochemistry 20041207
Dielectrophoretic micropatterning with microparticle monolayers covalently linked to glass surfaces. Langmuir : the ACS journal of surfaces and colloids 20041207
A novel method for coupling doxorubicin to lactosaminated human albumin by an acid sensitive hydrazone bond: synthesis, characterization and preliminary biological properties of the conjugate. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20041201
Structural characterization of organic multilayers on silicon(111) formed by immobilization of molecular films on functionalized Si-C linked monolayers. Langmuir : the ACS journal of surfaces and colloids 20041012
Synthesis and potent antitumor activities of novel 1,3,5-cis,cis-triaminocyclohexane N-pyridyl derivatives. Journal of medicinal chemistry 20041007
Mechanism of prion propagation: amyloid growth occurs by monomer addition. PLoS biology 20041001
Derivative of alpha,beta-dicyanostilbene: convenient precursor for the synthesis of diphenylmaleimide compounds, E-Z isomerization, crystal structure, and solid-state fluorescence. The Journal of organic chemistry 20040917
Carbon-carbon bond formation by radical addition-fragmentation reactions of O-alkylated enols. Organic & biomolecular chemistry 20040907
Architecture of a Diels-Alderase ribozyme with a preformed catalytic pocket. Chemistry & biology 20040901
'Cystope tagging' for labeling and detection of recombinant protein expression. Analytical biochemistry 20040815
The topography of transmembrane segment six is altered during the catalytic cycle of P-glycoprotein. The Journal of biological chemistry 20040813
The immunogenicity of the tumor-associated antigen Lewis(y) may be suppressed by a bifunctional cross-linker required for coupling to a carrier protein. Chemistry (Weinheim an der Bergstrasse, Germany) 20040719
Relative proximity and orientation of helices 4 and 8 of the GLUT1 glucose transporter. The Journal of biological chemistry 20040618
Design, synthesis, and biological evaluation of novel 7-azaindolyl-heteroaryl-maleimides as potent and selective glycogen synthase kinase-3beta (GSK-3beta) inhibitors. Bioorganic & medicinal chemistry 20040615
The protein kinase C inhibitor bisindolyl maleimide 2 binds with reversed orientations to different conformations of protein kinase A. The Journal of biological chemistry 20040528
Design and synthesis of alpha Gal-conjugated peptide T20 as novel antiviral agent for HIV-immunotargeting. Organic & biomolecular chemistry 20040307
Cy5 maleimide labelling for sensitive detection of free thiols in native protein extracts: identification of seed proteins targeted by barley thioredoxin h isoforms. The Biochemical journal 20040301
About thiol derivatization and resolution of basic proteins in two-dimensional electrophoresis. Proteomics 20040301
Polymer-coated polyethylenimine/DNA complexes designed for triggered activation by intracellular reduction. The journal of gene medicine 20040301
cAMP-dependent protein kinase regulatory subunit type IIbeta: active site mutations define an isoform-specific network for allosteric signaling by cAMP. The Journal of biological chemistry 20040220
Analysis of the membrane topology for transmembrane domains 7-12 of the human reduced folate carrier by scanning cysteine accessibility methods. The Biochemical journal 20040215
General strategy for the preparation of membrane permeable fluorogenic peptide ester conjugates for in vivo studies of ester prodrug stability. Bioorganic & medicinal chemistry 20040201
Eosin-5-maleimide binding to band 3 and Rh-related proteins forms the basis of a screening test for hereditary spherocytosis. British journal of haematology 20040101
Five new maleic and succinic acid derivatives from the mycelium of Antrodia camphorata and their cytotoxic effects on LLC tumor cell line. Journal of natural products 20040101
Use of luminescence resonance energy transfer to measure distances in the AE1 anion exchange protein dimer. Blood cells, molecules & diseases 20040101
Design and synthesis of a new polymer drug delivery conjugate. Biomedical sciences instrumentation 20040101
Synthesis of thiol-reactive lipopeptide adjuvants. Incorporation into liposomes and study of their mitogenic effect on mouse splenocytes. Bioconjugate chemistry 20040101
Hemoglobin-based oxygen carriers. Critical care (London, England) 20040101
Engineering surfaces for bioconjugation: developing strategies and quantifying the extent of the reactions. Bioconjugate chemistry 20040101
[Using thioGlo-1 for the determination of thiols in brain tissue]. Biomeditsinskaia khimiia 20040101
Synthesis and biological activity of water-soluble maleimide derivatives of the anticancer drug carboplatin designed as albumin-binding prodrugs. Bioconjugate chemistry 20040101
Coupling of metal containing homing devices to liposomes via a maleimide linker: use of TCEP to stabilize thiol-groups without scavenging metals. Journal of drug targeting 20040101
Thiol-reactive clenbuterol analogues conjugated to bovine serum albumin. Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101
Catechol-substituted L-chicoric acid analogues as HIV integrase inhibitors. Bioorganic & medicinal chemistry letters 20031215
Phase I clinical trial of the bispecific antibody MDX-H210 (anti-FcgammaRI x anti-HER-2/neu) in combination with Filgrastim (G-CSF) for treatment of advanced breast cancer. British journal of cancer 20031215
A novel cold-adapted imidase from fish Oreochromis niloticus that catalyzes hydrolysis of maleimide. Biochemical and biophysical research communications 20031212
Polymer-assisted solution-phase (PASP) Suzuki couplings employing an anthracene-tagged palladium catalyst. The Journal of organic chemistry 20031212
Experience with eosin-5'-maleimide as a diagnostic tool for red cell membrane cytoskeleton disorders. Clinical and laboratory haematology 20031201
Study of in vitro and in vivo effects of 1,6-Bis[4-(4-amino-3-hydroxyphenoxy)phenyl]diamantane (DPD), a novel cytostatic and differentiation inducing agent, on human colon cancer cells. British journal of cancer 20031117
Structural and functional roles of Cys-238 and Cys-295 in Escherichia coli phosphofructokinase-2. The Biochemical journal 20031115
A core-shell-type fluorescent nanosphere possessing reactive poly(ethylene glycol) tethered chains on the surface for zeptomole detection of protein in time-resolved fluorometric immunoassay. Analytical chemistry 20031115
Laser flash photolysis of bismaleimides. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20031101
Synthesis of oligonucleotide conjugates via aqueous Diels-Alder cycloaddition. Current protocols in nucleic acid chemistry 20031101
Synthesis and biological activity of photoactivatable N-ras peptides and proteins. Journal of the American Chemical Society 20031022
Cholic acid as template for multivalent peptide assembly. Organic & biomolecular chemistry 20031021
Synthesis and in vitro analysis of atrial natriuretic peptide-albumin conjugates. Bioorganic & medicinal chemistry letters 20031020
Tailoring structure-function and pharmacokinetic properties of single-chain Fv proteins by site-specific PEGylation. Protein engineering 20031001
Molybdenum amido complexes with single Mo-N bonds: synthesis, structure, and reactivity. Chemistry (Weinheim an der Bergstrasse, Germany) 20030905
Electron cryomicroscopy structure of N-ethyl maleimide sensitive factor at 11 A resolution. The EMBO journal 20030901
Comprehensive two-dimensional separation system by coupling capillary reverse-phase liquid chromatography to capillary isoelectric focusing for peptide and protein mapping with laser-induced fluorescence detection. Electrophoresis 20030901
The influence of split doses of gamma-radiation on human erythrocytes. Journal of radiation research 20030901
Fluorescence resonance energy transfer studies on anthrax lethal toxin. FEBS letters 20030828
Accessibility of cysteine residues in a cytoplasmic loop of CitS of Klebsiella pneumoniae is controlled by the catalytic state of the transporter. Biochemistry 20030819
The synthesis of acid- and base-labile lipopeptides on solid support. Chemistry (Weinheim an der Bergstrasse, Germany) 20030804
Beta-glycosylamidine as a ligand for affinity chromatography tailored to the glycon substrate specificity of beta-glycosidases. Carbohydrate research 20030704
Thiol-reactive dyes for fluorescence labeling of proteomic samples. Electrophoresis 20030701
Characterization of maleimide-activated Ca2+ entry in neutrophils. Biochemical pharmacology 20030615
Detection of DNA probes using Diels Alder cycloaddition and SERRS. The Analyst 20030601
Monitoring the cellular surface display of recombinant proteins by cysteine labeling and flow cytometry. Chembiochem : a European journal of chemical biology 20030509
A peptide trivalent arsenical inhibits tumor angiogenesis by perturbing mitochondrial function in angiogenic endothelial cells. Cancer cell 20030501
Enabling ScFvs as multi-drug carriers: a dendritic approach. Bioorganic & medicinal chemistry 20030417
Quantification of binding of some thiol-reactive clenbuterol analogues to bovine serum albumin by electron paramagnetic resonance spectroscopy. Analytical biochemistry 20030415
A rapid stereocontrolled entry to the ABCD tetracyclic core of neotuberostemonine. Angewandte Chemie (International ed. in English) 20030411
MP4, a new nonvasoactive PEG-Hb conjugate. Transfusion 20030401
Patch-clamp fluorometry recording of conformational rearrangements of ion channels. Science's STKE : signal transduction knowledge environment 20030401
Use of a fluorescent maleimide to probe structure-function relationships in stalk segments 4 and 5 of the yeast plasma-membrane H+-ATPase. Annals of the New York Academy of Sciences 20030401
Cavity-directed synthesis within a self-assembled coordination cage: highly selective [2 + 2] cross-photodimerization of olefins. Journal of the American Chemical Society 20030319
Why asparagine needs carbohydrates to generate acrylamide. Journal of agricultural and food chemistry 20030312
Synthesis of 6H-pyrrolo[3',4':2,3][1,4]diazepino[6,7,1-hi]indole-8,10(7H,9H)-diones using 3-bromo-4-(indol-1-yl)maleimide scaffold. Organic & biomolecular chemistry 20030307
Familial amyotrophic lateral sclerosis mutants of copper/zinc superoxide dismutase are susceptible to disulfide reduction. The Journal of biological chemistry 20030221
Carbohydrate-centered maleimide cluster as a new type of templates for multivalent peptide assembling. synthesis of multivalent HIV-1 gp41 peptides. Bioorganic & medicinal chemistry 20030102
Synthesis of maleimide-activated carbohydrates as chemoselective tags for site-specific glycosylation of peptides and proteins. Bioconjugate chemistry 20030101
Maleimide-oligo(ethylene glycol) derivatives of camptothecin as albumin-binding prodrugs: synthesis and antitumor efficacy. Bioconjugate chemistry 20030101
Site-specific PEGylation of hemoglobin at Cys-93(beta): correlation between the colligative properties of the PEGylated protein and the length of the conjugated PEG chain. Bioconjugate chemistry 20030101
Coupling of importin beta binding peptide on plasmid DNA: transfection efficiency is increased by modification of lipoplex's physico-chemical properties. BMC biotechnology 20030101
Thiol-reactive luminescent lanthanide chelates: part 2. Bioconjugate chemistry 20030101
Affinity capture-facilitated preparation of aequorin- oligonucleotide conjugates for rapid hybridization assays. Bioconjugate chemistry 20030101
Novel method for the covalent immobilization of oligonucleotides via Diels-Alder bioconjugation. Nucleosides, nucleotides & nucleic acids 20030101
Synthesis of a new heterobifunctional linker, N-[4-(aminooxy)butyl]maleimide, for facile access to a thiol-reactive 18F-labeling agent. Bioconjugate chemistry 20030101
Origins and predictions of stereoselective antibody catalysis: theoretical analysis of Diels-Alder catalysis by 39A11 and its germ-line antibody. The Journal of organic chemistry 20021213
Human T cells resistant to complement lysis by bivalent antibody can be efficiently lysed by dimers of monovalent antibody. Blood 20021201
Spatial redox regulation of a critical cysteine residue of NF-kappa B in vivo. The Journal of biological chemistry 20021115
Synthesis of 1,3,5-cis,cis-triaminocyclohexane N-pyridyl derivatives as potential antitumor agents. The Journal of organic chemistry 20021115
Stalk segment 5 of the yeast plasma membrane H(+)-ATPase. Labeling with a fluorescent maleimide reveals a conformational change during glucose activation. The Journal of biological chemistry 20021025
Synthesis of poly(maleimide-co-2-ethylacrylic acid) and its properties of suppressing metastasis and growth of carcinoma. Bioorganic & medicinal chemistry letters 20021021
Role of critical thiol groups on the matrix surface of the adenine nucleotide translocase in the mechanism of the mitochondrial permeability transition pore. The Biochemical journal 20021015
Expression and structure-function analysis of de, a sperm cysteine-rich secretory protein that mediates gamete fusion. Biology of reproduction 20021001
A new approach to oligonucleotide labelling using Diels-Alder cycloadditions and detection by SERRS. Chemical communications (Cambridge, England) 20020921
A method for bioconjugation of carbohydrates using Diels-Alder cycloaddition. Organic letters 20020919
Deprotonation and dimerization of maleimide in the triplet state: a laser flash photolysis study with optical and conductometric detection. Chemistry (Weinheim an der Bergstrasse, Germany) 20020916
2-Ethyl-3-methylmaleimide in Tokyo Bay sediments providing the first evidence for its formation from chlorophylls in the present photic and oxygenic zone. Bioscience, biotechnology, and biochemistry 20020901
Syntheses of dendritic linkers containing chlorambucil residues for the preparation of antibody-multidrug immunoconjugates. Bioorganic & medicinal chemistry letters 20020819
Crystal structure of 1:1 complex crystal between 4-(3-methoxybenzyloxy)-6-methyl-2-pyrone and maleimide. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20020801
Synthesis of pegylated immunonanoparticles. Pharmaceutical research 20020801
Binding of hemoglobin to red cell membranes with eosin-5-maleimide-labeled band 3: analysis of centrifugation and fluorescence data. Biochemistry 20020709
Cytotoxic targeting of F9 teratocarcinoma tumours with anti-ED-B fibronectin scFv antibody modified liposomes. British journal of cancer 20020701
Novel [6 + 2] cycloaddition of fulvenes with alkenes: a facile synthesis of the anislactone and hirsutane framework. Organic letters 20020627
Structure/function relationships in OxlT, the oxalate/formate antiporter of Oxalobacter formigenes: assignment of transmembrane helix 2 to the translocation pathway. The Journal of biological chemistry 20020607
Chromaffin cell catecholamine secretion: bisindolylmaleimide compounds exhibit novel and potent antagonist effects at the nicotinic cholinergic receptor in pheochromocytoma cells. Molecular pharmacology 20020601
Solid-phase synthesis of lipidated peptides. Journal of the American Chemical Society 20020529
Tumour targeting of humanised cross-linked divalent-Fab' antibody fragments: a clinical phase I/II study. British journal of cancer 20020506
Photochemistry of benzotriazole: an unprecedented tautomer-selective intermolecular [2+2] photocycloaddition. Organic letters 20020502
Maleimide is a potent inhibitor of topoisomerase II in vitro and in vivo: a new mode of catalytic inhibition. Molecular pharmacology 20020501
Probing the membrane topology of a subunit of the mitochondrial protein translocase, Tim44, with biotin maleimide. Biochemical and biophysical research communications 20020426
Cell-dependent differential cellular uptake of PNA, peptides, and PNA-peptide conjugates. Antisense & nucleic acid drug development 20020401
Optical properties of the synthetic nanocomposites SiO2/CdS/poly(styrene-co-maleic anhydride) and SiO2/CdS/poly(styrene-co-maleimide). Journal of nanoscience and nanotechnology 20020401
Total synthesis of the CP-molecules (CP-263,114 and CP-225,917, phomoidrides B and A). 3. Completion and synthesis of advanced analogues. Journal of the American Chemical Society 20020313
Fluorescence studies of pyrene maleimide-labeled translin: excimer fluorescence indicates subunits associate in a tail-to-tail configuration to form octamer. Biochemistry 20020312
Close location of the first loop to the third loop of the mitochondrial ADP/ATP carrier deduced from cross-linking catalyzed by copper-o-phenanthroline of the solubilized carrier with Triton X-100. Journal of biochemistry 20020301
Systemic tumor-targeted gene delivery by anti-transferrin receptor scFv-immunoliposomes. Molecular cancer therapeutics 20020301
The first two cantharidin analogues displaying PP1 selectivity. Bioorganic & medicinal chemistry letters 20020211
A generic recognition-based approach to the acceleration of cycloaddition reactions. Organic letters 20020124
Synthesis, characterization, photophysical properties, and biological labeling studies of a series of luminescent rhenium(I) polypyridine maleimide complexes. Inorganic chemistry 20020114
UV resonance Raman study of beta93-modified hemoglobin A: chemical modifier-specific effects and added influences of attached poly(ethylene glycol) chains. Biochemistry 20020108
Preparation of a conjugate of 2',5'-triadenylate 5'-triphosphate and biotinylated firefly luciferase and its use for sensitive bioluminescent enzyme immunoassay. Bioconjugate chemistry 20020101
Utility of thiol-cross-linked fluorescent dye labeled terminators for DNA sequencing. Bioconjugate chemistry 20020101
The himanimides, new bioactive compounds from Serpula himantoides (Fr.) Karst. Zeitschrift fur Naturforschung. C, Journal of biosciences 20020101
Modifications in synthesis strategy improve the yield and efficacy of geldanamycin-herceptin immunoconjugates. Bioconjugate chemistry 20020101
Identification of redox-active proteins on cell surface. Methods in enzymology 20020101
Effect of nucleotides and their analogues on essential light chains in myosin head. Journal of biochemical and biophysical methods 20020101
Analysis of integral membrane protein contributions to the deformability and stability of the human erythrocyte membrane. The Journal of biological chemistry 20011214
Stratum corneum protein dynamics as evaluated by a spin-label maleimide derivative: effect of urea. Biophysical journal 20011201
Pegylation: a method for assessing topological accessibilities in Kv1.3. Biochemistry 20011106
Cysteine-directed cross-linking localizes regions of the human erythrocyte anion-exchange protein (AE1) relative to the dimeric interface. The Biochemical journal 20011101
Pro-oxidant and antioxidant mechanisms of etoposide in HL-60 cells: role of myeloperoxidase. Cancer research 20011101
High-performance liquid chromatographic method to analyze picomole levels of glutathione, cysteine and cysteinylglycine and its application to pre-cancerous rat livers. Journal of chromatography. B, Biomedical sciences and applications 20011005
A new gene delivery formulation of polyethylenimine/DNA complexes coated with PEG conjugated fusogenic peptide. Journal of controlled release : official journal of the Controlled Release Society 20010911
Characterization of loops of the yeast mitochondrial ADP/ATP carrier facing the cytosol by site-directed mutagenesis. Biochemical and biophysical research communications 20010907
Facile three-component coupling procedure for the synthesis of substituted tetrahydroisoindole-1,3-diones from alpha,beta-unsaturated aldehydes. Organic letters 20010906
Identification of a region involved in the communication between the NADP(H) binding domain and the membrane domain in proton pumping E. coli transhydrogenase. Biochemistry 20010821
Development and in vitro efficacy of novel MMP2 and MMP9 specific doxorubicin albumin conjugates. Bioorganic & medicinal chemistry letters 20010806
Beta 93 modified hemoglobin: kinetic and conformational consequences. Biochemistry 20010626
Monitoring the conformational fluctuations of DNA hairpins using single-pair fluorescence resonance energy transfer. Journal of the American Chemical Society 20010509
Constrained modeling of spin-labeled major coat protein mutants from M13 bacteriophage in a phospholipid bilayer. Protein science : a publication of the Protein Society 20010501
Effect of peptide-carrier coupling on peptide-specific immune responses. Immunobiology 20010501
Cyclization strategies for the synthesis of macrocyclic bisindolylmaleimides. The Journal of organic chemistry 20010323
Transfer of stereochemical information in a minimal self-replicating system. Organic letters 20010308
Synthesis of functional Ras lipoproteins and fluorescent derivatives. Journal of the American Chemical Society 20010214
Cysteine residues in the D-galactose-H+ symport protein of Escherichia coli: effects of mutagenesis on transport, reaction with N-ethylmaleimide and antibiotic binding. The Biochemical journal 20010201
Carbohydrate-directed conjugation of cobra venom factor to antibody by selective derivatization of the terminal galactose residues. Bioconjugate chemistry 20010101
Studies on protein-liposome coupling using novel thiol-reactive coupling lipids: influence of spacer length and polarity. Bioconjugate chemistry 20010101
Synthesis and characterization of a ruthenium(II)-based redox conjugate for reagentless biosensing. Bioconjugate chemistry 20010101
Ferredoxin-NADP reductase is involved in the ferredoxin-dependent cyclic electron transport in isolated thylakoids. Doklady. Biochemistry and biophysics 20010101
Circular dichroism of some optically active 2,3-dichloromaleimides. Enantiomer 20010101
Preparation of Fab' from murine IgG2a for thiol reactive conjugation. Journal of drug targeting 20010101
FTIR study of five complex beta-lactam molecules. Biopolymers 20010101

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