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53-96-3 | N-(9H-Fluoren-2-yl)acetamide
CAS No: 53-96-3 Catalog No: AG003S9D MDL No:MFCD00001116
Product Description
Catalog Number:
AG003S9D
Chemical Name:
N-(9H-Fluoren-2-yl)acetamide
CAS Number:
53-96-3
Molecular Formula:
C15H13NO
Molecular Weight:
223.2698
MDL Number:
MFCD00001116
IUPAC Name:
N-(9H-fluoren-2-yl)acetamide
InChI:
InChI=1S/C15H13NO/c1-10(17)16-13-6-7-15-12(9-13)8-11-4-2-3-5-14(11)15/h2-7,9H,8H2,1H3,(H,16,17)
InChI Key:
CZIHNRWJTSTCEX-UHFFFAOYSA-N
SMILES:
CC(=O)Nc1ccc2c(c1)Cc1c2cccc1
EC Number:
200-188-6
UNII:
9M98QLJ2DL
NSC Number:
12279
RTECS Number:
AB9450000
UN Number:
3077
Properties
Complexity:
301
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
223.1g/mol
Formal Charge:
0
Heavy Atom Count:
17
Hydrogen Bond Acceptor Count:
1
Hydrogen Bond Donor Count:
1
Isotope Atom Count:
0
Molecular Weight:
223.275g/mol
Monoisotopic Mass:
223.1g/mol
Rotatable Bond Count:
1
Topological Polar Surface Area:
29.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3.3
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| Low selection of preneoplastic hepatocytes after treatment with the 2-acetylaminofluorene diet-partial hepatectomy regimen in the liver of hepatocarcinogenesis-resistant DRH strain rats. | Oncology reports 20070101 |
| Novel hepatic progenitor cell surface markers in the adult rat liver. | Hepatology (Baltimore, Md.) 20070101 |
| [Effect of acupoint-injection of oxymatrine on experimental hepatic carcinoma and study on the mechanism]. | Zhongguo zhen jiu = Chinese acupuncture & moxibustion 20070101 |
| Effects of oral administration of berberine on distribution and metabolism of 2-aminofluorene in Sprague-Dawley rats. | In vivo (Athens, Greece) 20070101 |
| Persistent activation of NF-kappaB related to IkappaB's degradation profiles during early chemical hepatocarcinogenesis. | Journal of carcinogenesis 20070101 |
| Suppression of early stages of neoplastic transformation in a two-stage chemical hepatocarcinogenesis model: supplementation of vanadium, a dietary micronutrient, limits cell proliferation and inhibits the formations of 8-hydroxy-2'-deoxyguanosines and DNA strand-breaks in the liver of sprague-dawley rats. | Nutrition and cancer 20070101 |
| Transcriptional networks in S. cerevisiae linked to an accumulation of base excision repair intermediates. | PloS one 20070101 |
| Lack of initiation activity of 4-oxo-2-hexenal, a peroxidation product generated from omega-3 polyunsaturated fatty acids, in an in vivo five-week liver assay. | Asian Pacific journal of cancer prevention : APJCP 20070101 |
| Protective effects of Picorrhiza kurroa extract against 2-acetylaminofluorene-induced hepatotoxicity in Wistar rats. | Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20070101 |
| Differences in gene expression profiles in the liver between carcinogenic and non-carcinogenic isomers of compounds given to rats in a 28-day repeat-dose toxicity study. | Toxicology and applied pharmacology 20061215 |
| A comparative study on the antimutagenic properties of aqueous extracts of Aspalathus linearis (rooibos), different Cyclopia spp. (honeybush) and Camellia sinensis teas. | Mutation research 20061210 |
| Zonal hierarchy of differentiation markers and nestin expression during oval cell mediated rat liver regeneration. | Histochemistry and cell biology 20061201 |
| The oncofetal protein glypican-3 is a novel marker of hepatic progenitor/oval cells. | Laboratory investigation; a journal of technical methods and pathology 20061201 |
| [Inducement effect of matrine on phenotype changes of rat hepatic oval cells]. | Ai zheng = Aizheng = Chinese journal of cancer 20061201 |
| A single dose of caffeic acid phenethyl ester prevents initiation in a medium-term rat hepatocarcinogenesis model. | World journal of gastroenterology 20061114 |
| Prospero-related homeobox 1 (Prox1) is a stable hepatocyte marker during liver development, injury and regeneration, and is absent from 'oval cells'. | Histochemistry and cell biology 20061101 |
| Characterization of two distinct liver progenitor cell subpopulations of hematopoietic and hepatic origins. | Experimental cell research 20060910 |
| Evaluation of possible mechanisms of protective role of Tamarix gallica against DEN initiated and 2-AAF promoted hepatocarcinogenesis in male Wistar rats. | Life sciences 20060905 |
| Biochemical basis of genotoxicity of heterocyclic arylamine food mutagens: Human DNA polymerase eta selectively produces a two-base deletion in copying the N2-guanyl adduct of 2-amino-3-methylimidazo[4,5-f]quinoline but not the C8 adduct at the NarI G3 site. | The Journal of biological chemistry 20060901 |
| Dynamic alteration of telomerase expression and its diagnostic significance in liver or peripheral blood for hepatocellular carcinoma. | World journal of gastroenterology 20060821 |
| Application of a color-shift model with heterogeneous growth to a rat hepatocarcinogenesis experiment. | Mathematical biosciences 20060801 |
| Arsenic exposure is associated with decreased DNA repair in vitro and in individuals exposed to drinking water arsenic. | Environmental health perspectives 20060801 |
| Critique of dose response in carcinogenesis. | Human & experimental toxicology 20060701 |
| The nongenotoxic carcinogens naphthalene and para-dichlorobenzene suppress apoptosis in Caenorhabditis elegans. | Nature chemical biology 20060601 |
| Liver initiation activity of norfloxacin but not nalidixic acid, pipemidic acid, and ciprofloxacin on in vivo short-term liver initiation assay in rats. | Toxicology 20060515 |
| Vanadium inhibits the development of 2-acetylaminofluorene-induced premalignant phenotype in a two-stage chemical rat hepatocarcinogenesis model. | Life sciences 20060508 |
| Role of Nrf2 in the regulation of the Mrp2 (ABCC2) gene. | The Biochemical journal 20060501 |
| A potential role of somatostatin and its receptor SSTR4 in the migration of hepatic oval cells. | Laboratory investigation; a journal of technical methods and pathology 20060501 |
| [Effects of GSM 1800 MHz radiofrequency electromagnetic fields on DNA damage in Chinese hamster lung cells]. | Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20060501 |
| DNA damage evaluated by gammaH2AX foci formation by a selective group of chemical/physical stressors. | Mutation research 20060430 |
| Early induction of TGF-beta1 through a fasting-re-feeding regimen promotes liver carcinogenesis by a sub-initiating dose of diethylnitrosamine. | Cell proliferation 20060401 |
| The role of pregnane X receptor in 2-acetylaminofluorene-mediated induction of drug transport and -metabolizing enzymes in mice. | Drug metabolism and disposition: the biological fate of chemicals 20060301 |
| The role of p28GANK in rat oval cells activation and proliferation. | Liver international : official journal of the International Association for the Study of the Liver 20060301 |
| Hepatic gene induction in murine bone marrow after hepatectomy. | Journal of hepatology 20060201 |
| A dual and opposite effect of Calendula officinalis flower extract: chemoprotector and promoter in a rat hepatocarcinogenesis model. | Planta medica 20060201 |
| Inactivation of recG stimulates the RecF pathway during lesion-induced recombination in E. coli. | DNA repair 20060105 |
| Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion. | PLoS biology 20060101 |
| Characteristics of rat bone marrow cells differentiated into a liver cell lineage and dynamics of the transplanted cells in the injured liver. | Journal of gastroenterology 20060101 |
| Gene expression dose-response of liver with a genotoxic and nongenotoxic carcinogen. | International journal of toxicology 20060101 |
| Ketoprofen-inhibited N-acetyltransferase activity and gene expression in human colon tumor cells. | Anticancer research 20060101 |
| Chemoprevention by Butea monosperma of hepatic carcinogenesis and oxidative damage in male wistar rats. | Asian Pacific journal of cancer prevention : APJCP 20060101 |
| Preventive effect of tannic acid on 2-acetylaminofluorene induced antioxidant level, tumor promotion and hepatotoxicity: a chemopreventive study. | Redox report : communications in free radical research 20060101 |
| Expression of AFP and Rev-Erb A/Rev-Erb B and N-CoR in fetal rat liver, liver injury and liver regeneration. | Comparative hepatology 20060101 |
| Carcinogen-modified DNA and specific humoral immunity toward carcinogen-DNA adducts. A review. | Annali dell'Istituto superiore di sanita 20060101 |
| Pentachlorophenol inhibits micronuclei induction by 2-acetylaminofluorene but not by thioacetamide. | Environmental toxicology and pharmacology 20060101 |
| Effect of inhibition of aloe-emodin on N-acetyltransferase activity and gene expression in human malignant melanoma cells (A375.S2). | Melanoma research 20051201 |
| Role of HSP90, CDC37, and CRM1 as modulators of P16(INK4A) activity in rat liver carcinogenesis and human liver cancer. | Hepatology (Baltimore, Md.) 20051201 |
| Mechanism for N-acetyl-2-aminofluorene-induced frameshift mutagenesis by Escherichia coli DNA polymerase I (Klenow fragment). | Biochemistry 20051122 |
| Hepatocyte growth factor accelerates the proliferation of hepatic oval cells and possibly promotes the differentiation in a 2-acetylaminofluorene/partial hepatectomy model in rats. | Journal of gastroenterology and hepatology 20051101 |
| Anti-hepatoma effect of arsenic trioxide on experimental liver cancer induced by 2-acetamidofluorene in rats. | World journal of gastroenterology 20051014 |
| Novel antimutagenic factors derived from the edible mushroom Agrocybe cylindracea. | Mutation research 20051003 |
| Berberine inhibits arylamine N-acetyltransferase activity and gene expression in Salmonella typhi. | Current microbiology 20051001 |
| Antimutagenic and anti-oxidant activities of the non-steroidal anti-inflammatory drug celecoxib. | Clinical and experimental pharmacology & physiology 20051001 |
| Immunohistochemical analysis of cytokeratin 7 expression in resting and proliferating biliary structures of rat liver. | Hepatology (Baltimore, Md.) 20051001 |
| [Proliferation and differentiation of C-kit+ cell in vitro]. | Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20051001 |
| Transcriptome analysis of rat liver regeneration in a model of oval hepatic stem cells. | Genomics 20050901 |
| Identification of genes specific to 'oval cells' in the rat 2-acetylaminofluorene/partial hepatectomy model. | Histochemistry and cell biology 20050901 |
| Recognition and incision of gamma-radiation-induced cross-linked guanine-thymine tandem lesion G[8,5-Me]T by UvrABC nuclease. | Chemical research in toxicology 20050901 |
| Comet assay with the fish cell line rainbow trout gonad-2 for in vitro genotoxicity testing of xenobiotics and surface waters. | Environmental toxicology and chemistry 20050801 |
| Time-resolved resonance Raman observation of the 2-fluorenylnitrenium ion reaction with guanosine to form a C8 intermediate. | Journal of the American Chemical Society 20050615 |
| Altered expression of cytochrome P450 and possible correlation with preneoplastic changes in early stage of rat hepatocarcinogenesis. | Acta pharmacologica Sinica 20050601 |
| Role of connective tissue growth factor in oval cell response during liver regeneration after 2-AAF/PHx in rats. | Gastroenterology 20050601 |
| Comparisons of thresholds for carcinogenicity on linear and logarithmic dosage scales. | Human & experimental toxicology 20050601 |
| Protection against 2- acetyl aminofluorene-induced toxicity in mice by garlic (Allium sativum), bitter kola (Garcina kola seed) and honey. | African journal of medicine and medical sciences 20050601 |
| Cooperative interaction of human XPA stabilizes and enhances specific binding of XPA to DNA damage. | Biochemistry 20050517 |
| Statistical analysis of current status data with informative observation times. | Statistics in medicine 20050515 |
| Lack of p53 Ser389 phosphorylation predisposes mice to develop 2-acetylaminofluorene-induced bladder tumors but not ionizing radiation-induced lymphomas. | Cancer research 20050501 |
| Inhibitory effect of celery seeds extract on chemically induced hepatocarcinogenesis: modulation of cell proliferation, metabolism and altered hepatic foci development. | Cancer letters 20050418 |
| Different inhibitory effects in the early and late phase of treatment with KAT-681, a liver-selective thyromimetic, on rat hepatocarcinogenesis induced by 2-acetylaminofluorene and partial hepatectomy after diethylnitrosamine initiation. | Toxicological sciences : an official journal of the Society of Toxicology 20050301 |
| Vanadium induces apoptosis and modulates the expressions of metallothionein, Ki-67 nuclear antigen, and p53 during 2-acetylaminofluorene-induced rat liver preneoplasia. | Journal of cellular biochemistry 20050301 |
| Oncostatin M inhibits proliferation of rat oval cells, OC15-5, inducing differentiation into hepatocytes. | The American journal of pathology 20050301 |
| Downregulation of apoptosis revealed by laser microdissection and cDNA microarray analysis of related genes in rat liver preneoplastic lesions. | Medical molecular morphology 20050301 |
| The amoebicidal aqueous extract from Castela texana possesses antigenotoxic and antimutagenic properties. | Toxicology in vitro : an international journal published in association with BIBRA 20050201 |
| Comparison of different initiation protocols in the resistant hepatocyte model. | Toxicology 20050131 |
| Interactions of human replication protein A with single-stranded DNA adducts. | The Biochemical journal 20050115 |
| 2-AAF-induced tumor development in nucleotide excision repair-deficient mice is associated with a defect in global genome repair but not with transcription coupled repair. | DNA repair 20050102 |
| Effects of ellagic acid by oral administration on distribution and metabolism of 2-aminofluorene in Sprague-Dawley rats. | In vivo (Athens, Greece) 20050101 |
| Effects of aspirin on the in vitro and in vivo acetylation of 2-aminofluorene in Sprague-Dawley rats. | In vivo (Athens, Greece) 20050101 |
| Wogonin inhibits N-acetyltransferase activity and gene expression in human leukemia HL-60 cells. | Anticancer research 20050101 |
| Characterization of a novel protein that specifically binds to DNA modified by N-acetoxy-acetylaminofluorene and cis-diamminedichloroplatinum. | Acta biochimica Polonica 20050101 |
| Effects of 5-methoxypsoralen (5-MOP) on arylamine N-acetyltransferase activity in the stomach and colon of rats and human stomach and colon tumor cell lines. | In vivo (Athens, Greece) 20050101 |
| Mechanism of frameshift (deletion) generated by acetylaminofluorene-derived DNA adducts in vitro. | Biochemistry 20041221 |
| Suppression of diethylnitrosamine and 2-acetylaminofluorene-induced hepatocarcinogenesis in rats by tocotrienol-rich fraction isolated from rice bran oil. | European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20041201 |
| Expression of Dlk/Pref-1 defines a subpopulation in the oval cell compartment of rat liver. | Gene expression patterns : GEP 20041201 |
| Expression of stromal cell-derived factor-1 and of its receptor CXCR4 in liver regeneration from oval cells in rat. | The American journal of pathology 20041201 |
| Mutagenic properties of 3-(deoxyguanosin-N2-yl)-2-acetylaminofluorene, a persistent acetylaminofluorene-derived DNA adduct in mammalian cells. | Biochemistry 20041130 |
| Analysis of the involvement of human N-acetyltransferase 1 in the genotoxic activation of bladder carcinogenic arylamines using a SOS/umu assay system. | Mutation research 20041004 |
| Embryonic turkey liver: activities of biotransformation enzymes and activation of DNA-reactive carcinogens. | Archives of toxicology 20041001 |
| Comparison of the chemopreventive efficacies of garlic powders with different alliin contents against aflatoxin B1 carcinogenicity in rats. | Carcinogenesis 20041001 |
| DNA repair efficiency and thermotolerance in Drosophila melanogaster from 'Evolution Canyon'. | Mutagenesis 20040901 |
| Establishment of ten strains of genetically engineered Salmonella typhimurium TA1538 each co-expressing a form of human cytochrome P450 with NADPH-cytochrome P450 reductase sensitive to various promutagens. | Mutation research 20040808 |
| Inhibitory effects of KAT-681, a liver-selective thyromimetic, on development of hepatocellular proliferative lesions in rats induced by 2-acetylaminofluorene and partial hepatectomy after diethylnitrosamine initiation. | Archives of toxicology 20040801 |
| p53 heterozygosity results in an increased 2-acetylaminofluorene-induced urinary bladder but not liver tumor response in DNA repair-deficient Xpa mice. | Cancer research 20040801 |
| Discriminating different classes of toxicants by transcript profiling. | Environmental health perspectives 20040801 |
| Interferon alpha-induced apoptosis on rat preneoplastic liver is mediated by hepatocytic transforming growth factor beta(1). | Hepatology (Baltimore, Md.) 20040801 |
| Modulation of altered hepatic foci induction by diallyl sulphide in Wistar rats. | European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20040801 |
| Disruption of sphingolipid biosynthesis in hepatocyte nodules: selective proliferative stimulus induced by fumonisin B1. | Toxicology 20040715 |
| Fumonisin B1-induced hepatocellular and cholangiocellular tumors in male Fischer 344 rats: potentiating effects of 2-acetylaminofluorene on oval cell proliferation and neoplastic development in a discontinued feeding study. | Carcinogenesis 20040701 |
| Mitoinhibitory effects of the tumor promoter 2-acetylaminofluorene in rat liver: loss of E2F-1 and E2F-3 expression and cdk 2 kinase activity in late G1. | Journal of hepatology 20040601 |
| Comparison of basal gene expression profiles and effects of hepatocarcinogens on gene expression in cultured primary human hepatocytes and HepG2 cells. | Mutation research 20040518 |
| Characterization and enrichment of hepatic progenitor cells in adult rat liver. | World journal of gastroenterology 20040515 |
| Initiating activity of 4-chlorobiphenyl metabolites in the resistant hepatocyte model. | Toxicological sciences : an official journal of the Society of Toxicology 20040501 |
| 2-acetylaminofluorene dose-dependent differentiation of rat oval cells into hepatocytes: confocal and electron microscopic studies. | Hepatology (Baltimore, Md.) 20040501 |
| Induction of preneoplastic altered hepatic foci following dietary sulphur supplementation. | Human & experimental toxicology 20040501 |
| Gene expression profiles in liver regeneration with oval cell induction. | Biochemical and biophysical research communications 20040430 |
| The autoradiographic test for unscheduled DNA synthesis: a sensitive assay for the detection of DNA repair in the HepG2 cell line. | Mutation research 20040411 |
| Acute molecular markers of rodent hepatic carcinogenesis identified by transcription profiling. | Chemical research in toxicology 20040401 |
| Ex vivo modulation of chemical-induced mutagenesis by subcellular liver fractions of rats treated with rooibos (Aspalathus linearis) tea, honeybush (Cyclopia intermedia) tea, as well as green and black (Camellia sinensis) teas. | Mutation research 20040314 |
| Assessment of the performance of the Ames II assay: a collaborative study with 19 coded compounds. | Mutation research 20040314 |
| IFN-alpha prevents the growth of pre-neoplastic lesions and inhibits the development of hepatocellular carcinoma in the rat. | Carcinogenesis 20040301 |
| Specific differences in gene expression profile revealed by cDNA microarray analysis of glutathione S-transferase placental form (GST-P) immunohistochemically positive rat liver foci and surrounding tissue. | Carcinogenesis 20040301 |
| Inhibition of liver carcinogenesis in Wistar rats by consumption of an aqueous extract from leaves of Ardisia compressa. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040301 |
| Mass spectrometric investigation of the mechanism of inactivation of hamster arylamine N-acetyltransferase 1 by N-hydroxy-2-acetylaminofluorene. | Chemical research in toxicology 20040301 |
| Histological and lipid peroxidation changes after administration of 2-acetylaminofluorene in a rat liver injury model following selective periportal and pericentral damage. | Toxicology 20040301 |
| Antimutagenicity of herbal detoxification formula Smoke Shield against environmental mutagens. | Journal of experimental & clinical cancer research : CR 20040301 |
| Chemical modification of hamster arylamine N-acetyltransferase 2 with isozyme-selective and nonselective N-arylbromoacetamido reagents. | The protein journal 20040201 |
| Chemically induced immunotoxicity in a medium-term multiorgan bioassay for carcinogenesis with Wistar rats. | Toxicology and applied pharmacology 20040115 |
| 2-Acetylaminofluorene inhibits interleukin-1beta production in LPS-stimulated macrophages by blocking NF-kappaB/Rel activation. | Cancer letters 20040108 |
| Interactions between N-acetylcysteine and sodium selenite in modulating the clastogenicity of urethane and 2-acetylaminofluorene in mice. | International journal of cancer 20040101 |
| PCR and flow cytometric analysis of paclitaxel-inhibited arylamine N-acetyltransferase activity and gene expression in human osteogenic sarcoma cells (U-2 OS). | Anticancer research 20040101 |
| The origin of biliary ductular cells that appear in the spleen after transplantation of hepatocytes. | Cell transplantation 20040101 |
| Effect of cacao liquor extract on tumor marker enzymes during chemical hepatocarcinogenesis in rats. | Journal of medicinal food 20040101 |
| Thresholds for the effects of 2-acetylaminofluorene in rat liver. | Toxicologic pathology 20040101 |
| Bone marrow progenitors are not the source of expanding oval cells in injured liver. | Stem cells (Dayton, Ohio) 20040101 |
| Potential anticancer effect of red spinach (Amaranthus gangeticus) extract. | Asia Pacific journal of clinical nutrition 20040101 |
| Infiltrating CD8+ T lymphocytes, natural killer cells, and expression of IL-10 and TGF-beta1 in chemically induced neoplasms in male Wistar rats. | Toxicologic pathology 20040101 |
| Chemopreventive effect of indole-3-carbinol on induction of preneoplastic altered hepatic foci. | Nutrition and cancer 20040101 |
| Paclitaxel inhibits N-acetyltransferase activity and gene expression in human stomach tumor cells (SC-M1). | Research communications in molecular pathology and pharmacology 20040101 |
| 2-Acetylaminofluorene. | Report on carcinogens : carcinogen profiles 20040101 |
| Modulation of doxorubicin sensitivity by a novel organic compound, oxalyl bis (N-phenyl) hydroxamic acid on acetyl aminofluorene-induced preneoplastic hepatocytes. | Cancer letters 20031208 |
| Establishment of Alb-DsRed2 transgenic rat for liver regeneration research. | Biochemical and biophysical research communications 20031114 |
| Effects of DNA adduct structure and sequence context on strand opening of repair intermediates and incision by UvrABC nuclease. | Biochemistry 20031104 |
| Arylamine N-acetyltransferases: covalent modification and inactivation of hamster NAT1 by bromoacetamido derivatives of aniline and 2-aminofluorene. | Journal of protein chemistry 20031101 |
| Aloe-emodin inhibited N-acetylation and DNA adduct of 2-aminofluorene and arylamine N-acetyltransferase gene expression in mouse leukemia L 1210 cells. | Leukemia research 20030901 |
| Waddell's representation of the tumor incidence data of the ED01 study is strongly misleading. | Toxicological sciences : an official journal of the Society of Toxicology 20030901 |
| Thresholds in carcinogenicity in ED01 study. | Toxicological sciences : an official journal of the Society of Toxicology 20030901 |
| STAT-3 activity in chemically-induced hepatocellular carcinoma. | European journal of cancer (Oxford, England : 1990) 20030901 |
| Estimation of k for the poly-k test with application to animal carcinogenicity studies. | Statistics in medicine 20030830 |
| Blockage of transcription as a trigger for p53 accumulation by 2-acetylaminofluorene DNA-adducts. | Life sciences 20030822 |
| Early resistance to cell death and to onset of the mitochondrial permeability transition during hepatocarcinogenesis with 2-acetylaminofluorene. | Proceedings of the National Academy of Sciences of the United States of America 20030819 |
| Evidence of a 'clear and consistent threshold' for bladder and liver cancer in the large ED01 carcinogenicity study. | Toxicological sciences : an official journal of the Society of Toxicology 20030801 |
| Thresholds of carcinogenicity in the ED01 study. | Toxicological sciences : an official journal of the Society of Toxicology 20030801 |
| ATP binding cassette transporter gene expression in rat liver progenitor cells. | Gut 20030701 |
| Hepatic oval cells have the side population phenotype defined by expression of ATP-binding cassette transporter ABCG2/BCRP1. | The American journal of pathology 20030701 |
| Effects of different mitogens on intrasplenic liver tissue transplants in comparison to orthotopic liver. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20030601 |
| Uncoupling of leading- and lagging-strand DNA replication during lesion bypass in vivo. | Science (New York, N.Y.) 20030523 |
| Use of HepG2 cell line for direct or indirect mutagens screening: comparative investigation between comet and micronucleus assays. | Mutation research 20030420 |
| Mechanistic insights into replication across from bulky DNA adducts: a mutant polymerase I allows an N-acetyl-2-aminofluorene adduct to be accommodated during DNA synthesis. | Biochemistry 20030408 |
| Differentially expressed transcripts in neoplastic hepatic nodules and neonatal rat liver studied by cDNA microarray analysis. | International journal of cancer 20030320 |
| Thresholds of carcinogenicity in the ED01 study. | Toxicological sciences : an official journal of the Society of Toxicology 20030301 |
| Suppressive effect of herbal compound 861 on chemical hepatocarcinogenesis in rats. | Chinese medical journal 20030301 |
| Pregnane X receptor-dependent and -independent effects of 2-acetylaminofluorene on cytochrome P450 3A23 expression and liver cell proliferation. | Biochemical and biophysical research communications 20030110 |
| Use of nucleotide excision repair-deficient mice as a model for chemically induced lung cancer. | Methods in molecular medicine 20030101 |
| Suppressive effect of Astragalus membranaceus Bunge on chemical hepatocarcinogenesis in rats. | Cancer chemotherapy and pharmacology 20030101 |
| Mutagenic activation of arylamines by subcellular fractions of Chamaelea gallina clams exposed to environmental pollutants. | Environmental and molecular mutagenesis 20030101 |
| Genomic structure, gene expression, and promoter analysis of human multidrug resistance-associated protein 7. | Journal of biomedical science 20030101 |
| Polychlorinated biphenyls as initiators in liver carcinogenesis: resistant hepatocyte model. | Toxicology and applied pharmacology 20030101 |
| Prevalidation of a rat liver foci bioassay (RLFB) based on results from 1600 rats: a study report. | Toxicologic pathology 20030101 |
| Different effects of the liver mitogens triiodo-thyronine and ciprofibrate on the development of rat hepatocellular carcinoma. | Toxicologic pathology 20030101 |
| Suppression of altered hepatic foci development by curcumin in wistar rats. | Nutrition and cancer 20030101 |
| Paclitaxel affects the amounts of the N-acetylation of 2-aminofluorene and DNA-2-aminofluorene adduct formation in Sprague-Dawley rats. | In vivo (Athens, Greece) 20030101 |
| Reply to Gaylor. Data for high dose and low dose that do not visually fall near a line representing the other data. | Toxicologic pathology 20030101 |
| Vanadium suppresses sister-chromatid exchange and DNA-protein crosslink formation and restores antioxidant status and hepatocellular architecture during 2-acetylaminofluorene-induced experimental rat hepatocarcinogenesis. | Journal of experimental therapeutics & oncology 20030101 |
| Correspondance: Waddell WJ, Thresholds in chemical carcinogenesis: what are animal experiments telling us? | Toxicologic pathology 20030101 |
| Peroxisomal enzymes and 8-hydroxydeoxyguanosine in rat liver treated with perfluorooctanoic acid. | Disease markers 20030101 |
| In vivo effects of black cohosh and genistein on estrogenic activity and lipid peroxidation in Japanese Medaka (Oryzias latipes). | Journal of herbal pharmacotherapy 20030101 |
| Distinction of carcinogens from mutagens by induction of liver cell foci in a model for detection of initiation activity. | Cancer letters 20021215 |
| Mutagenic events in Escherichia coli and mammalian cells generated in response to acetylaminofluorene-derived DNA adducts positioned in the Nar I restriction enzyme site. | Biochemistry 20021203 |
| Oxidative DNA damage by a common metabolite of carcinogenic nitrofluorene and N-acetylaminofluorene. | International journal of cancer 20021201 |
| Deacylation of N-arylformamides and N-arylacetamides by formamidase in rat liver. | Drug metabolism and disposition: the biological fate of chemicals 20021201 |
| Protection by beverages, fruits, vegetables, herbs, and flavonoids against genotoxicity of 2-acetylaminofluorene and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in metabolically competent V79 cells. | Mutation research 20021126 |
| Influence of different chemicals on MDR-1 P-glycoprotein expression and activity in the HK-2 proximal tubular cell line. | Toxicology and applied pharmacology 20020901 |
| Chemical models for cytochrome P450 as a biomimetic metabolic activation system in mutation assays. | Mutation research 20020826 |
| The Liverbeads as a tool for the comet assay. | Mutation research 20020826 |
| Trapping of DNA nucleotide excision repair factors by nonrepairable carcinogen adducts. | Cancer research 20020801 |
| Anticarcinogenicity of monocyclic phenolic compounds. | European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20020801 |
| Embryoid-body cells derived from a mouse embryonic stem cell line show differentiation into functional hepatocytes. | Hepatology (Baltimore, Md.) 20020701 |
| The isomerization of the UvrB-DNA preincision complex couples the UvrB and UvrC activities. | Journal of molecular biology 20020628 |
| Pleiotrophin/heparin-binding growth-associated molecule as a mitogen of rat hepatocytes and its role in regeneration and development of liver. | The American journal of pathology 20020601 |
| In vivo cell lineage analysis during chemical hepatocarcinogenesis in rats using retroviral-mediated gene transfer: evidence for dedifferentiation of mature hepatocytes. | Laboratory investigation; a journal of technical methods and pathology 20020601 |
| [Establishment and optimization of rat models for hepatic oval cells proliferation]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20020601 |
| The effect of paclitaxel on 2-aminofluorene-DNA adducts formation and arylamine N-acetyltransferase activity and gene expression in human lung tumor cells (A549). | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20020501 |
| Alterations of the Fhit gene in hepatocellular carcinomas induced by N-nitrosodiethylamine in rats. | Molecular carcinogenesis 20020501 |
| The in vivo apoptotic effect of interferon alfa-2b on rat preneoplastic liver involves Bax protein. | Hepatology (Baltimore, Md.) 20020401 |
| Polyetheretherketone--cytotoxicity and mutagenicity in vitro. | Biomaterials 20020401 |
| Acute cytotoxicity of the chemical carcinogen 2-acetylaminofluorene in cultured rat liver epithelial cells. | Toxicology letters 20020328 |
| Induction of human MDR1 gene expression by 2-acetylaminofluorene is mediated by effectors of the phosphoinositide 3-kinase pathway that activate NF-kappaB signaling. | Oncogene 20020327 |
| 32P-Postlabeling/polyacrylamide gel electrophoresis analysis: application to the detection of DNA adducts. | Chemical research in toxicology 20020301 |
| Genetics of mutagenesis in E. coli: various combinations of translesion polymerases (Pol II, IV and V) deal with lesion/sequence context diversity. | DNA repair 20020227 |
| Germ cells microsatellite instability. The effect of different mutagens in a mismatch repair mutant of Drosophila (spel1). | Mutation research 20020215 |
| In vivo cell lineage analysis in cyproterone acetate-treated rat liver using genetic labeling of hepatocytes. | Hepatology (Baltimore, Md.) 20020201 |
| Lack of DNA binding in the rat nasal mucosa and other tissues of the nasal toxicants roflumilast, a phosphodiesterase 4 inhibitor, and a metabolite, 4-amino-3,5-dichloropyridine, in contrast to the nasal carcinogen 2,6-dimethylaniline. | Drug and chemical toxicology 20020201 |
| Effects of butylated hydroxyanisole and butylated hydroxytoluene on DNA adduct formation and arylamine N-acetyltransferase activity in human bladder tumour cells. | Journal of applied toxicology : JAT 20020101 |
| Proliferation and differentiation of ductular progenitor cells and littoral cells during the regeneration of the rat liver to CCl4/2-AAF injury. | Histology and histopathology 20020101 |
| Alteration of liver cell function and proliferation: differentiation between adaptation and toxicity. | Toxicologic pathology 20020101 |
| Anti-mutagenic activity of Phyllanthus amarus Schum & Thonn in vitro as well as in vivo. | Teratogenesis, carcinogenesis, and mutagenesis 20020101 |
| Hydrocortisone affects the N-acetylation of 2-aminofluorene and DNA-2-aminofluorene adduct formation in Sprague-Dawley rats. | Anticancer research 20020101 |
| The drug efflux pump MRP2: regulation of expression in physiopathological situations and by endogenous and exogenous compounds. | Cell biology and toxicology 20020101 |
| Effects of garlic components diallyl sulfide and diallyl disulfide on arylamine N-acetyltransferase activity and 2-aminofluorene-DNA adducts in human promyelocytic leukemia cells. | The American journal of Chinese medicine 20020101 |
| SDF-1alpha/CXCR4: a mechanism for hepatic oval cell activation and bone marrow stem cell recruitment to the injured liver of rats. | Cloning and stem cells 20020101 |
| 2-Acetylaminofluorene. | Report on carcinogens : carcinogen profiles 20020101 |
| Translesional synthesis past acetylaminofluorene-derived DNA adducts catalyzed by human DNA polymerase kappa and Escherichia coli DNA polymerase IV. | Biochemistry 20011218 |
| Detection of DNA adducts using a quantitative long PCR technique and the fluorogenic 5' nuclease assay (TaqMan). | Mutation research 20011212 |
| Leukemia inhibitory factor decreases the arylamine N-acetyltransferase activity in human cumulus granulosa cells. | Journal of assisted reproduction and genetics 20011201 |
| Ellagic [correction of ellagica] acid inhibits arylamine N-acetyltransferase activity and DNA adduct formation in human bladder tumor cell lines (T24 and TSGH 8301). | Urological research 20011201 |
| Induction of tumor clones in D. melanogaster wts/+ heterozygotes with chemical carcinogens. | Mutation research 20011115 |
| Ciprofloxacin: in vivo genotoxicity studies. | Mutation research 20011115 |
| Basal expression of the rat, but not of the human, multidrug resistance protein 2 (MRP2) gene is mediated by CBF/NF-Y and Sp1 promoter-binding sites. | Toxicology 20011005 |
| Regulation of biliary drug efflux pump expression by hormones and xenobiotics. | Toxicology 20011005 |
| Lack of effect of furfural on unscheduled DNA synthesis in the in vivo rat and mouse hepatocyte DNA repair assays and in precision-cut human liver slices. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20011001 |
| Inheritance of resistance to promotion of preneoplastic liver lesions in Copenhagen rats. | Experimental biology and medicine (Maywood, N.J.) 20011001 |
| Preventive effects of anthraquinone food pigments on the DNA damage induced by carcinogens in Drosophila. | Mutation research 20010901 |
| Matrix metalloproteinases-2 and 9 do not play a role in the growth of preneoplastic liver lesions in F344 rats. | Experimental biology and medicine (Maywood, N.J.) 20010901 |
| Cancer initiation by fumonisin B(1) in rat liver--role of cell proliferation. | Cancer letters 20010828 |
| Increased levels of cytosolic thioredoxin reductase activity and mRNA in rat liver nodules. | Journal of hepatology 20010801 |
| Luteolin-inhibited arylamine N-acetyltransferase activity and DNA-2-aminofluorene adduct in human and mouse leukemia cells. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20010701 |
| 1Alpha,25-dihydroxyvitamin D3 inhibits hepatic chromosomal aberrations, DNA strand breaks and specific DNA adducts during rat hepatocarcinogenesis. | Cellular and molecular life sciences : CMLS 20010701 |
| Induction of -2 frameshift mutations by 2-nitrofluorene, N-hydroxyacetylaminofluorene, and N-2-acetylaminofluorene in reversion assays in Escherichia coli strains differing in permeability and acetyltransferase activity. | Mutation research 20010627 |
| Cancer predisposition in mutant mice defective in multiple genetic pathways: uncovering important genetic interactions. | Mutation research 20010602 |
| Hepatocarcinogenesis inhibition by caffeine in ACI rats treated with 2-acetylaminofluorene. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20010601 |
| The contribution of UDP-glucuronosyltransferase 1A9 on CYP1A2-mediated genotoxicity by aromatic and heterocyclic amines. | Carcinogenesis 20010601 |
| DNA polymerases II and V mediate respectively mutagenic (-2 frameshift) and error-free bypass of a single N-2-acetylaminofluorene adduct. | Biochemical Society transactions 20010501 |
| Optimization of an exogenous metabolic activation system for FETAX. I. Post-isolation rat liver microsome mixtures. | Drug and chemical toxicology 20010501 |
| Origin and structural evolution of the early proliferating oval cells in rat liver. | The American journal of pathology 20010401 |
| [Expression of rasp21, C-myc, C-erbB-2, and AFP in 2-FAA induced experimental hepatocarcinogenesis]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20010401 |
| Investigation of commercial Mitolife as an antioxidant and antimutagen. | Nutrition (Burbank, Los Angeles County, Calif.) 20010401 |
| Up-regulation of transporters of the MRP family by drugs and toxins. | Toxicology letters 20010331 |
| The role of nucleotide excision repair and loss of p53 in mutagenesis and carcinogenesis. | Toxicology letters 20010331 |
| Influence of flanking sequence context on the mutagenicity of acetylaminofluorene-derived DNA adducts in mammalian cells. | Biochemistry 20010327 |
| Metabolism of 2-nitrofluorene, an environmental pollutant, and 2-acetylaminofluorene in fish. | Bulletin of environmental contamination and toxicology 20010301 |
| Total energy of deoxyguanosine bonded to N-2-acetylaminofluorene by the semi-empirical modified-neglect of differential diatomic overlap method. | Mutation research 20010220 |
| Uridine uptake inhibition as a cytotoxicity test for a human hepatoma cell line (HepG2 cells): comparison with the neutral red assay. | Toxicology 20010214 |
| 2-acetylaminofluorene up-regulates rat mdr1b expression through generating reactive oxygen species that activate NF-kappa B pathway. | The Journal of biological chemistry 20010105 |
| Purification and characterization of pol kappa, a DNA polymerase encoded by the human DINB1 gene. | The Journal of biological chemistry 20010105 |
| Influence of processing stages on antimutagenic and antioxidant potentials of rooibos tea. | Journal of agricultural and food chemistry 20010101 |
| Characterization of a new rat cell line established from 2'AAF-induced combined hepatocellular cholangiocellular carcinoma. | In vitro cellular & developmental biology. Animal 20010101 |
| Ellagic acid inhibited 2-aminofluorene and p-aminobenzoic acid acetylation by mononuclear leucocytes from Sprague-Dawley rats. | Cytobios 20010101 |
| Anti-tumor promoting activity of Asteracantha longifolia against experimental hepatocarcinogenesis in rats. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20010101 |
| Comparison of hprt and lacI mutant frequency with DNA adduct formation in N-hydroxy-2-acetylaminofluorene-treated Big Blue rats. | Environmental and molecular mutagenesis 20010101 |
| Metabolism of 2-nitrofluorene, 2-aminofluorene and 2-acylaminofluorenes in rat and dog and the role of intestinal bacteria. | Xenobiotica; the fate of foreign compounds in biological systems 20010101 |
| Effects of the butylated hydroxyanisole and butylated hydroxytoluene on the DNA adduct formation and arylamines N-acetyltransferase activity in human colon tumor cells. | Anticancer research 20010101 |
| Morphological transformation of Syrian hamster embryo cells at pH 6.7 by bemitradine, a nongenotoxic carcinogen. | In vitro & molecular toxicology 20010101 |
| Xpa and Xpa/p53+/- knockout mice: overview of available data. | Toxicologic pathology 20010101 |
| Vitamin A and all-trans and 9-cis retinoic acids inhibit cell proliferation during the progression phase of hepatocarcinogenesis in Wistar rats. | Nutrition and cancer 20010101 |
| Tamoxifen inhibits arylamine N-acetyltransferase activity and DNA-2-aminofluorene adduct in human leukemia HL-60 cells. | Research communications in molecular pathology and pharmacology 20010101 |
| Loss of nuclear p53 protein in preneoplastic rat hepatocytes is accompanied by Mdm2 and Bcl-2 overexpression and by defective response to DNA damage in vivo. | Hepatology (Baltimore, Md.) 20001001 |
| Endotoxin downregulates hepatic expression of P-glycoprotein and MRP2 in 2-acetylaminofluorene-treated rats. | Molecular cell biology research communications : MCBRC 20000801 |
| Impaired nuclear accumulation and shortened phosphorylation of ERK after growth factor stimulation in cultured hepatocytes from rats exposed to 2-acetylaminofluorene. | Molecular carcinogenesis 20000601 |
| Reduction of hydroxamic acids to the corresponding amides catalyzed by rabbit blood. | Xenobiotica; the fate of foreign compounds in biological systems 20000501 |
| Characterization of the 5'-flanking region of the human multidrug resistance protein 2 (MRP2) gene and its regulation in comparison withthe multidrug resistance protein 3 (MRP3) gene. | European journal of biochemistry 20000301 |
| The carcinogen 2-acetylaminofluorene inhibits activation and nuclear accumulation of cyclin-dependent kinase 2 in growth-induced rat liver. | Molecular carcinogenesis 20000301 |
| Bile acid secretion during rat liver carcinogenesis. | Life sciences 20000211 |
| Diet restriction increases ubiquinone contents and inhibits progression of hepatocellular carcinoma in the rat. | Scandinavian journal of gastroenterology 20000101 |
| The slow induction of resistant hepatocytes during initiation of hepatocarcinogenesis by the nongenotoxic carcinogen clofibrate. | Experimental and molecular pathology 19991201 |
| Transplantation of fetal liver tissue suspension into the spleens of adult syngenic rats: effects of various mitogens and cytotoxins on cytochrome P450 (P450) isoforms expression and on P450 mediated monooxygenase functions. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 19990701 |
| c-fos gene expression in rat liver is induced by phenobarbital. | Cancer letters 19990129 |
| Natural killer activity in a medium-term multi-organ bioassay for carcinogenesis. | Japanese journal of cancer research : Gann 19990101 |
| A new approach to identifying genotoxic carcinogens: p53 induction as an indicator of genotoxic damage. | Carcinogenesis 19980601 |
| Effects of the lignan, arctiin, on 17-beta ethinyl estradiol promotion of preneoplastic liver cell foci development in rats. | Anticancer research 19980101 |
| Bile ductular damage induced by methylene dianiline inhibits oval cell activation. | The American journal of pathology 19971001 |
| Influence of liver tumor promoters on apoptosis in rat hepatocytes induced by 2-acetylaminofluorene, ultraviolet light, or transforming growth factor beta 1. | Cancer research 19960315 |
| Accumulation of p53 protein in chemically induced oval cells during early stages of rodent hepatocarcinogenesis. | Carcinogenesis 19950401 |
| Initiator-specific promotion of hepatocarcinogenesis by WY-14,643 and clofibrate. | Carcinogenesis 19940801 |
| Correlation between S-adenosyl-L-methionine content and production of c-myc, c-Ha-ras, and c-Ki-ras mRNA transcripts in the early stages of rat liver carcinogenesis. | Cancer letters 19940429 |
| Effect of 4-acetylaminofluorene and other tumour promoters on hepatocellular growth and binucleation. | Carcinogenesis 19940201 |
| Genotoxic potency in Drosophila melanogaster of selected aromatic amines and polycyclic aromatic hydrocarbons as assayed in the DNA repair test. | Mutation research 19931201 |
| Frequency and DNA content of micronuclei in rat parenchymal liver cells during experimental hepatocarcinogenesis. | Carcinogenesis 19931101 |
| Modifying effects of various chemicals on tumor development in a rat wide-spectrum organ carcinogenesis model. | Japanese journal of cancer research : Gann 19920801 |
| Age-dependent induction of preneoplastic liver cell foci by 2-acetylaminofluorene, phenobarbital and acetaminophen in F344 rats initially treated with diethylnitrosamine. | Japanese journal of cancer research : Gann 19910301 |
| Metabolism of 2-acetylaminofluorene and benzo(a)pyrene and activation of food-derived heterocyclic amine mutagens by human cytochromes P-450. | Cancer research 19900601 |
| Abnormal neurulation induced by 7-hydroxy-2-acetylaminofluorene and acetaminophen: evidence for catechol metabolites as proximate dysmorphogens. | Toxicology and applied pharmacology 19891201 |
| Synergistic effects of low-dose hepatocarcinogens in induction of glutathione S-transferase P-positive foci in the rat liver. | Japanese journal of cancer research : Gann 19891001 |
| Strain differences in susceptibility to 2-acetylaminofluorene and phenobarbital promotion of rat hepatocarcinogenesis in a medium-term assay system: quantitation of glutathione S-transferase P-positive foci development. | Japanese journal of cancer research : Gann 19891001 |
| Changes in gap junction protein (connexin 32) gene expression during rat liver carcinogenesis. | Journal of cellular biochemistry 19891001 |
| A method for in vitro culture of rat Zymbal gland: use in mechanistic studies of benzene carcinogenesis in combination with 32P-postlabeling. | Environmental health perspectives 19890701 |
| Human liver microsomal cytochrome P-450 enzymes involved in the bioactivation of procarcinogens detected by umu gene response in Salmonella typhimurium TA 1535/pSK1002. | Cancer research 19890615 |
| Modulation of the embryotoxicity and cytotoxicity elicited by 7-hydroxy-2-acetylaminofluorene and acetaminophen via deacetylation. | Toxicology and applied pharmacology 19890301 |
| Induction of altered hepatocellular foci of hamster for a possible short-term assay for carcinogens. | Research communications in chemical pathology and pharmacology 19890301 |
| Neuroendocrine dysdifferentiation and bombesin production in carcinogen-induced hepatocellular rat tumours. | Carcinogenesis 19890101 |
| Arteriosclerotic plaque development is 'promoted' by polynuclear aromatic hydrocarbons. | Carcinogenesis 19881201 |
| Lack of expression of glutathione-S-transferase P, gamma-glutamyl transpeptidase, and alpha-fetoprotein messenger RNAs in liver tumors induced by peroxisome proliferators. | Cancer research 19880901 |
| Glutathione status and the incidence of neural tube defects elicited by direct acting teratogens in vitro. | Teratology 19880601 |
| Dose-dependent induction of liver and thyroid neoplastic lesions by short-term administration of 2-amino-3-methylimidazo[4,5-f]quinoline combined with partial hepatectomy followed by phenobarbital or low dose 3'-methyl-4-dimethylaminoazobenzene promotion. | Japanese journal of cancer research : Gann 19880601 |
| Inhibition of neoplastic development in rat liver, kidney, oesophagus and forestomach by 4,4'-diaminodiphenylmethane administration. | Carcinogenesis 19870501 |
| N-hydroxy-2-acetylaminofluorene as effective inhibitor of aldehyde oxidase. | Biochemical and biophysical research communications 19860716 |
| Effect of timing of partial hepatectomy on the induction of preneoplastic liver foci in rats given hepatocarcinogens. | Cancer letters 19860701 |
| Inhibitory effects of ethoxyquin, 4,4'-diaminodiphenylmethane and acetaminophen on rat hepatocarcinogenesis. | Japanese journal of cancer research : Gann 19860301 |
| Cytotoxicity of halogenated alkanes in primary cultures of rat hepatocytes from normal, partial hepatectomized, and preneoplastic/neoplastic liver. | Toxicology and applied pharmacology 19850915 |
| 5-azacytidine potentiates initiation induced by carcinogens in rat liver. | Carcinogenesis 19850101 |
| Absence of a promoting or sequential syncarcinogenic effect in rat liver by the carcinogenic hypolipidemic drug nafenopin given after N-2-fluorenylacetamide. | Toxicology and applied pharmacology 19850101 |
| Effects of the hepatocarcinogenic peroxisome-proliferating hypolipidemic agents clofibrate and nafenopin on the rat liver cell membrane enzymes gamma-glutamyltranspeptidase and alkaline phosphatase and on the early stages of liver carcinogenesis. | Carcinogenesis 19841201 |
| Modifying potential of thirty-one chemicals on the short-term development of gamma-glutamyl transpeptidase-positive foci in diethylnitrosamine-initiated rat liver. | Gan 19841001 |
| Cyclic modulation of enzymes of pyrimidine nucleotide biosynthesis precedes sialoglycoconjugate changes during 2-acetylaminofluorene-induced hepatocarcinogenesis in the rat. | Biochimica et biophysica acta 19840730 |
| Lack of initiating or promoting activity of six benzodiazepine tranquilizers in rat liver limited bioassays monitored by histopathology and assay of liver and plasma enzymes. | Fundamental and applied toxicology : official journal of the Society of Toxicology 19840401 |
| Dose-dependent reduction of N-2-fluorenylacetamide-induced liver cancer and enhancement of bladder cancer in rats by butylated hydroxytoluene. | Cancer research 19840401 |
| Modification of the development of N-nitrosomorpholine-induced hepatic lesions by 2-acetylaminofluorene, phenobarbital and 4,4'-diaminodiphenylmethane: a sequential histological and histochemical analysis. | Carcinogenesis 19840301 |
| Distinction between liver neoplasm promoting and syncarcinogenic effects demonstrated by exposure to phenobarbital or diethylnitrosamine either before or after N-2-fluorenylacetamide. | Carcinogenesis 19840201 |
| Comparison of oval cells induced in rat liver by feeding N-2-fluorenylacetamide in a choline-devoid diet and bile duct cells induced by feeding 4,4'-diaminodiphenylmethane. | Cancer research 19830401 |
| Comparison of the promoting effects of various agents in induction of preneoplastic lesions in rat liver. | Environmental health perspectives 19830401 |
| Phenobarbital as a promoter in the initiation/selection process of experimental rat hepatocarcinogenesis. | Carcinogenesis 19830101 |
| Limited in vivo bioassays on some benzodiazepines: lack of experimental initiating or promoting effect of the benzodiazepine tranquillizers diazepam, clorazepate, oxazepam and lorazepam. | Archives internationales de pharmacodynamie et de therapie 19820501 |
| Induction of hyperplastic liver nodules in hepatectomized rats treated with 3'-methyl-4-dimethylaminoazobenzene, benzo[a]pyrene or phenobarbital before or after exposure to N-2-fluorenylacetamide. | Gan 19820401 |
| In vitro carcinogenesis of hepatocytes obtained from acetylaminofluorene-treated rat liver and promotion of their growth by phenobarbital. | Gan 19801201 |
| Enhancing effect of inducers of liver microsomal enzymes on induction of hyperplastic liver nodules by N-2-fluorenylacetamide in rats. | Journal of the National Cancer Institute 19791201 |
| Subcellular distribution and properties of aldehyde dehydrogenase from 2-acetylaminofluorene-induced rat hepatomas. | The Biochemical journal 19791001 |
| Enhancement of rat hepatocellular-altered foci by the liver tumor promoter phenobarbital: evidence that foci are precursors of neoplasms and that the promoter acts on carcinogen-induced lesions. | Journal of the National Cancer Institute 19781101 |
| Lack of carcinogenicity of oxprenolol, a beta-adrenergic blocking agent. | Toxicology and applied pharmacology 19770901 |
| Enzymic deacetylation of carcinogenic arylacetamides by tissue microsomes of the dog and other species. | Journal of toxicology and environmental health 19760101 |
| Oxidative biotransformation of 2-acetylaminofluorene in fetal and placental tissues of humans and monkeys. Correlations with aryl hydrocarbon hydroxylase activities. | Drug metabolism and disposition: the biological fate of chemicals 19750101 |
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