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CAS No: 51543-40-9 Catalog No: AG003C3U MDL No:
Title | Journal |
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Flurbiprofen axetil promotes neuroprotection by activation of cerebral peroxisome proliferator-activated receptor gamma after focal cerebral ischemia in rats. | Chinese medical journal 20121001 |
Flurbiprofen axetil provides a prophylactic benefit against mesenteric traction syndrome associated with remifentanil infusion during laparotomy. | Journal of anesthesia 20120801 |
Non-steroidal anti-inflammatory drugs reduce the stress response during sevoflurane anesthesia. | Acta anaesthesiologica Scandinavica 20120801 |
Preemptive analgesic effects of flurbiprofen axetil in patients undergoing radical resection of esophageal carcinoma via the left thoracic approach. | Chinese medical journal 20120201 |
Metal chaperones: a holistic approach to the treatment of Alzheimer's disease. | Frontiers in psychiatry 20120101 |
Alzheimer's disease and the amyloid cascade hypothesis: a critical review. | International journal of Alzheimer's disease 20120101 |
Alzheimer's disease: a clinical practice-oriented review. | Frontiers in neurology 20120101 |
Anesthesia and perioperative management of colorectal surgical patients - A clinical review (Part 1). | Journal of anaesthesiology, clinical pharmacology 20120101 |
γ-Secretase modulator in Alzheimer's disease: shifting the end. | Journal of Alzheimer's disease : JAD 20120101 |
Discovery of 4-aminomethylphenylacetic acids as γ-secretase modulators via a scaffold design approach. | Bioorganic & medicinal chemistry letters 20111215 |
[Effect of continuous intravenous infusion of flurbiprofen axetil and tramadol hydrochloride for postoperative pain management of laparoscopic colectomy]. | Masui. The Japanese journal of anesthesiology 20111201 |
Alzheimer's disease: pathological mechanisms and recent insights. | Current neuropharmacology 20111201 |
[Gamma-secretase inhibitors and modulators]. | Nihon rinsho. Japanese journal of clinical medicine 20111201 |
Flurbiprofen axetil enhances analgesic effect of fentanyl associated with increase in β-endorphin levels. | Journal of anesthesia 20111001 |
Reduction of propofol injection pain by utilizing the gate control theory. | Korean journal of anesthesiology 20111001 |
Pharmacologists and Alzheimer disease therapy: to boldly go where no scientist has gone before. | Expert opinion on investigational drugs 20110901 |
Flurbiprofen axetil, nasal polyps, and status asthmaticus: an unusual case report. | The Journal of asthma : official journal of the Association for the Care of Asthma 20110801 |
Efficacy of the lidocaine/flurbiprofen axetil combination for reducing pain during the injection of propofol. | Minerva anestesiologica 20110701 |
Novel NSAIDs ophthalmic formulation: flurbiprofen axetil emulsion with low irritancy and improved anti-inflammation effect. | International journal of pharmaceutics 20110630 |
Design and evaluation of ocusert for controlled delivery of flurbiprofen sodium. | Current eye research 20110501 |
Predicting harms and benefits in translational trials: ethics, evidence, and uncertainty. | PLoS medicine 20110301 |
Acrylic acid-methyl methacrylate (2.5:7.5/2:8) enteric copolymer for colon targeted drug delivery. | Journal of materials science. Materials in medicine 20110101 |
Non-linear relationships of cerebrospinal fluid biomarker levels with cognitive function: an observational study. | Alzheimer's research & therapy 20110101 |
Neurovascular dysfunction, inflammation and endothelial activation: implications for the pathogenesis of Alzheimer's disease. | Journal of neuroinflammation 20110101 |
Corneal cross-linking for the treatment of keratoconus in a patient with ipsilateral myelinated retinal nerve fiber layer. | Case reports in ophthalmology 20110101 |
γ-secretase inhibitors and modulators for the treatment of Alzheimer's disease: disappointments and hopes. | Current topics in medicinal chemistry 20110101 |
Investigational drugs for the treatment of AD: what can we learn from negative trials? | Alzheimer's research & therapy 20110101 |
Glycogen synthase kinase 3 inhibitors in the next horizon for Alzheimer's disease treatment. | International journal of Alzheimer's disease 20110101 |
Predictors of long-term cognitive outcome in Alzheimer's disease. | Alzheimer's research & therapy 20110101 |
Lack of preemptive analgesia by intravenous flurbiprofen in thyroid gland surgery: a randomized, double-blind and placebo-controlled clinical trial. | International journal of medical sciences 20110101 |
Transumbilical laparo-endoscopic single site surgery for adrenal cortical adenoma inducing primary aldosteronism: initial experience. | BMC research notes 20110101 |
Galantamine treatment in Alzheimer's disease: response and long-term outcome in a routine clinical setting. | Neuropsychiatric disease and treatment 20110101 |
Interacting with γ-secretase for treating Alzheimer's disease: from inhibition to modulation. | Current medicinal chemistry 20110101 |
Neuroregenerative mechanisms of allopregnanolone in Alzheimer's disease. | Frontiers in endocrinology 20110101 |
Drug development for Alzheimer's disease: recent progress. | Experimental neurobiology 20101201 |
Why so few drugs for Alzheimer's disease? Are methods failing drugs? | Current Alzheimer research 20101101 |
[Population pharmacokinetic modeling of flurbiprofen]. | Yao xue xue bao = Acta pharmaceutica Sinica 20101101 |
Are we prepared to deal with the Alzheimer's disease pandemic? | Clinical pharmacology and therapeutics 20101001 |
Specialization without the Hospital: The Case of British Sports Medicine. | Medical history 20101001 |
Prevention of pain with the injection of microemulsion propofol: a comparison of a combination of lidocaine and ketamine with lidocaine or ketamine alone. | Korean journal of anesthesiology 20101001 |
Acrylic acid-methyl methacrylate copolymer for oral prolonged drug release. | Journal of materials science. Materials in medicine 20100901 |
Tarenflurbil in patients with mild Alzheimer's disease. | Current neurology and neuroscience reports 20100901 |
[Progress in the development of anti-amyloid drugs for treatment of Alzheimer's disease.]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20100701 |
[Drug therapy for Alzheimer's disease]. | Brain and nerve = Shinkei kenkyu no shinpo 20100701 |
Design, synthesis, and biological evaluation of a novel class of gamma-secretase modulators with PPARgamma activity. | Journal of medicinal chemistry 20100624 |
Why pleiotropic interventions are needed for Alzheimer's disease. | Molecular neurobiology 20100601 |
Tarenflurbil: mechanisms and myths. | Archives of neurology 20100601 |
Analgesic effect of parecoxib and flurbiprofen axetil for patients undergoing laparoscopic cholecystectomy and their influences on platelet aggregation. | Chinese medical journal 20100601 |
Disease-modifying drug fails in Alzheimer's study. | The Harvard mental health letter 20100401 |
Calcium signaling and neurodegeneration. | Acta naturae 20100401 |
[The effect of flurbiprofen axetil on laparoscopic cholecystectomy]. | Zhonghua yi xue za zhi 20100323 |
Tarenflurbil for Alzheimer's disease: a 'shot on goal' that missed. | The Lancet. Neurology 20100301 |
Update on the pharmacological treatment of Alzheimer's disease. | Current neuropharmacology 20100301 |
The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptide. | PloS one 20100101 |
Can novel therapeutics halt the amyloid cascade? | Alzheimer's research & therapy 20100101 |
Inflammation in the Alzheimer's disease cascade: culprit or innocent bystander? | Alzheimer's research & therapy 20100101 |
R-flurbiprofen reduces neuropathic pain in rodents by restoring endogenous cannabinoids. | PloS one 20100101 |
Effectiveness of a specific care plan in patients with Alzheimer's disease: cluster randomised trial (PLASA study). | BMJ (Clinical research ed.) 20100101 |
Presenilin/gamma-Secretase and Inflammation. | Frontiers in aging neuroscience 20100101 |
NSAIDs: How they Work and their Prospects as Therapeutics in Alzheimer's Disease. | Frontiers in aging neuroscience 20100101 |
Are NSAIDs useful to treat Alzheimer's disease or mild cognitive impairment? | Frontiers in aging neuroscience 20100101 |
NSAIDs may protect against age-related brain atrophy. | Frontiers in aging neuroscience 20100101 |
Use of theragnostic markers to select drugs for phase II/III trials for Alzheimer disease. | Alzheimer's research & therapy 20100101 |
Staging anti-inflammatory therapy in Alzheimer's disease. | Frontiers in aging neuroscience 20100101 |
Addressing the challenges to successful recruitment and retention in Alzheimer's disease clinical trials. | Alzheimer's research & therapy 20100101 |
Amyloid precursor protein selective gamma-secretase inhibitors for treatment of Alzheimer's disease. | Alzheimer's research & therapy 20100101 |
[Ion-sensitive nanoemulsion-in situ gel system for ophthalmic delivery of flurbiprofen axetil]. | Yao xue xue bao = Acta pharmaceutica Sinica 20100101 |
Infertility caused by tubal blockage: An ayurvedic appraisal. | Ayu 20100101 |
Effect of tarenflurbil on cognitive decline and activities of daily living in patients with mild Alzheimer disease: a randomized controlled trial. | JAMA 20091216 |
Late-life dementias: does this unyielding global challenge require a broader view? | JAMA 20091216 |
Epidemiological pathology of dementia: attributable-risks at death in the Medical Research Council Cognitive Function and Ageing Study. | PLoS medicine 20091101 |
Recent advances in the identification of gamma-secretase inhibitors to clinically test the Abeta oligomer hypothesis of Alzheimer's disease. | Journal of medicinal chemistry 20091022 |
The individual and combined effects of U50,488, and flurbiprofen axetil on visceral pain in conscious rats. | Anesthesia and analgesia 20090601 |
[Perioperative anesthetic management of a patient with multiple sclerosis]. | Masui. The Japanese journal of anesthesiology 20090601 |
Drug development for Alzheimer's disease: where are we now and where are we headed? | The American journal of geriatric pharmacotherapy 20090601 |
[Effect of preemptive analgesia with flurbiprofen axetil on patient-controlled intravenous analgesia with tramadol in patients undergoing postburn plastic surgery]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090601 |
Translational medicine lessons from flurizan's failure in Alzheimer's disease (AD) trial: Implication for future drug discovery and development for AD. | Clinical and translational science 20090601 |
What we have learned from the Myriad trials. | The journal of nutrition, health & aging 20090401 |
Pretreatment with flurbiprofen axetil, flurbiprofen axetil preceded by venous occlusion, and a mixture of flurbiprofen axetil and propofol in reducing pain on injection of propofol in adult Japanese surgical patients: a prospective, randomized, double-blind, placebo-controlled study. | Clinical therapeutics 20090401 |
[Postoperative analgesia with fentanyl combined with flurbiprofen axetil following gynecologic surgery for turnor]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090201 |
Progress in Alzheimer's disease drug discovery: an update. | Current opinion in investigational drugs (London, England : 2000) 20090101 |
Recent developments in Alzheimer's disease therapeutics. | BMC medicine 20090101 |
Intravenous flurbiprofen axetil can increase analgesic effect in refractory cancer pain. | Journal of experimental & clinical cancer research : CR 20090101 |
Why did tarenflurbil fail in Alzheimer's disease? | Journal of Alzheimer's disease : JAD 20090101 |
Disease-modifying approach to the treatment of Alzheimer's disease: from alpha-secretase activators to gamma-secretase inhibitors and modulators. | Drugs & aging 20090101 |
Alzheimer's disease therapeutic research: the path forward. | Alzheimer's research & therapy 20090101 |
The prevention and treatment of cognitive decline and dementia: An overview of recent research on experimental treatments. | Indian journal of psychiatry 20090101 |
Subpopulations of neurons in visual area v2 perform differentiation and integration operations in space and time. | Frontiers in systems neuroscience 20090101 |
Therapeutic time window of flurbiprofen axetil's neuroprotective effect in a rat model of transient focal cerebral ischemia. | Chinese medical journal 20081220 |
Impact of cholinesterase inhibitors on behavioral and psychological symptoms of Alzheimer's disease: a meta-analysis. | Clinical interventions in aging 20081201 |
Tarenflurbil protection from cytotoxicity is associated with an upregulation of neurotrophins. | Journal of Alzheimer's disease : JAD 20081101 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20081001 |
Present and prospective clinical therapeutic regimens for Alzheimer's disease. | Neuropsychiatric disease and treatment 20080801 |
Intravenous flurbiprofen axetil accelerates restoration of bowel function after colorectal surgery. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20080701 |
Topical ocular delivery of NSAIDs. | The AAPS journal 20080601 |
Efficacy and safety of tarenflurbil in mild to moderate Alzheimer's disease: a randomised phase II trial. | The Lancet. Neurology 20080601 |
Tarenflurbil: a shot on goal. | The Lancet. Neurology 20080601 |
Comparison of lidocaine, metoclopramide, and flurbiprofen axetil for reducing pain on injection of propofol in Japanese adult surgical patients: a prospective, randomized, double-blind, parallel-group, placebo-controlled study. | Clinical therapeutics 20080201 |
Dosage plan of a flurbiprofen injection product using inhibition of protein binding by lipid emulsion in rats. | The Journal of pharmacy and pharmacology 20080101 |
Selective amyloid-beta lowering agents. | BMC neuroscience 20080101 |
[Effect of postoperative analgesia with flurbiprofen axetil and sufentanyl on metabolism of surgical patients with intestinal carcinoma]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20071001 |
Topical antiinflammatory activity of an innovative aqueous formulation of actichelated propolis vs two commercial propolis formulations. | Phytotherapy research : PTR 20070901 |
Alzheimer's disease: progress in the development of anti-amyloid disease-modifying therapies. | CNS spectrums 20070201 |
Changing the course of Alzheimer's disease: anti-amyloid disease-modifying treatments on the horizon. | Primary care companion to the Journal of clinical psychiatry 20070101 |
Chronic administration of R-flurbiprofen attenuates learning impairments in transgenic amyloid precursor protein mice. | BMC neuroscience 20070101 |
Emulsion of flurbiprofen axetil reduces propofol injection pain due to a decrease in free propofol concentration. | Journal of anesthesia 20070101 |
[Clinical observation of propofol combined with flurbiprofen axetil for induced abortion anesthesia]. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20061001 |
Influence of age on flurbiprofen axetil requirements for preventing pain on injection of propofol in Japanese adult surgical patients: a prospective, randomized, double-blind, vehicle-controlled, parallel-group, dose-ranging study. | Clinical therapeutics 20060801 |
The geminal dimethyl analogue of Flurbiprofen as a novel Abeta42 inhibitor and potential Alzheimer's disease modifying agent. | Bioorganic & medicinal chemistry letters 20060415 |
Preparation and characterization of poly(D,L-lactic-co-glycolic Acid) microspheres containing flurbiprofen sodium. | Drug delivery 20060101 |
Preoperative administration of intravenous flurbiprofen axetil reduces postoperative pain for spinal fusion surgery. | Journal of anesthesia 20060101 |
Synthesis and biological activity of flurbiprofen analogues as selective inhibitors of beta-amyloid(1)(-)(42) secretion. | Journal of medicinal chemistry 20050908 |
Ambrosius Holbein's memento mori map for Sir Thomas More's Utopia. The meanings of a masterpiece of early sixteenth century graphic art. | British dental journal 20050723 |
2-Arylpropionic CXC chemokine receptor 1 (CXCR1) ligands as novel noncompetitive CXCL8 inhibitors. | Journal of medicinal chemistry 20050630 |
Flurbiprofen axetil preceded by venous occlusion in the prevention of pain on propofol injection in the hand: a prospective, randomized, double-blind, vehicle-controlled, dose-finding study in Japanese adult surgical patients. | Clinical therapeutics 20050501 |
The history of albuminous nephritis. 1840. | Medical history. Supplement 20050101 |
Pretreatment with flurbiprofen axetil and venous occlusion to reduce pain during injection of propofol. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20041201 |
Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. | Cell 20040109 |
Use of a wick to deliver preoperative mydriatics for cataract surgery. | Journal of cataract and refractive surgery 20031101 |
[The effect of ketamine on reducing postoperative agitation after sevoflurane anesthesia in pediatric strabismus surgery]. | Masui. The Japanese journal of anesthesiology 20021201 |
Flurbiprofen does not change the bispectral index and 95% spectral edge frequency during total intravenous anaesthesia with propofol and fentanyl. | European journal of anaesthesiology 20020701 |
Structural analysis of NSAID binding by prostaglandin H2 synthase: time-dependent and time-independent inhibitors elicit identical enzyme conformations. | Biochemistry 20010501 |
[Convulsion following the combination of single preoperative oral administration of enoxacine and single postoperative intravenous administration of flurbiprofen axetil]. | Masui. The Japanese journal of anesthesiology 20010401 |
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