200,000+ products from a single source!
sales@angenechem.com
Home > Imidazoles > 50924-49-7
50924-49-7 | 1H-Imidazole-4-carboxamide, 5-hydroxy-1-b-D-ribofuranosyl-
CAS No: 50924-49-7 Catalog No: AG00I94P MDL No:MFCD00057221
Product Description
Catalog Number:
AG00I94P
Chemical Name:
1H-Imidazole-4-carboxamide, 5-hydroxy-1-b-D-ribofuranosyl-
CAS Number:
50924-49-7
Molecular Formula:
C9H13N3O6
Molecular Weight:
259.2160
MDL Number:
MFCD00057221
IUPAC Name:
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxyimidazole-4-carboxamide
InChI:
InChI=1S/C9H13N3O6/c10-7(16)4-8(17)12(2-11-4)9-6(15)5(14)3(1-13)18-9/h2-3,5-6,9,13-15,17H,1H2,(H2,10,16)/t3-,5-,6-,9-/m1/s1
InChI Key:
HZQDCMWJEBCWBR-UUOKFMHZSA-N
SMILES:
OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc(c1O)C(=O)N
UNII:
4JR41A10VP
Properties
Complexity:
329
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
4
Defined Bond Stereocenter Count:
0
Exact Mass:
259.08g/mol
Formal Charge:
0
Heavy Atom Count:
18
Hydrogen Bond Acceptor Count:
7
Hydrogen Bond Donor Count:
5
Isotope Atom Count:
0
Molecular Weight:
259.218g/mol
Monoisotopic Mass:
259.08g/mol
Rotatable Bond Count:
3
Topological Polar Surface Area:
151A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-1.9
Literature
| Title | Journal |
|---|---|
| Profiling the immunotoxicity of chemicals based on in vitro evaluation by a combination of the Multi-ImmunoTox assay and the IL-8 Luc assay. | Archives of toxicology 20180601 |
| Efficacy and safety of multitarget therapy with mizoribine and tacrolimus for systemic lupus erythematosus with or without active nephritis. | Lupus 20121101 |
| Population pharmacokinetics of mizoribine in pediatric recipients of renal transplantation. | Clinical and experimental nephrology 20121001 |
| Mizoribine, tacrolimus, and corticosteroid combination therapy successfully induces remission in patients with lupus nephritis. | Clinical and experimental nephrology 20121001 |
| Effect of single-dose oral mizoribine pulse therapy twice per week for frequently relapsing steroid-dependent nephrotic syndrome. | Clinical nephrology 20120701 |
| Childhood nephrotic syndrome--current and future therapies. | Nature reviews. Nephrology 20120612 |
| Pharmacokinetics of mizoribine in adult living donor liver transplantation. | Transplantation proceedings 20120601 |
| Addition of mizoribine to the prednisolone plus tacrolimus treatment regimen in a patient with lupus flare. | Rheumatology international 20120401 |
| GSTT1 gene abnormality in minimal change nephrotic syndrome with elevated serum immunoglobulin E. | Clinical nephrology 20120401 |
| Mizoribine--an inosine monophosphate dehydrogenase inhibitor--acts synergistically with cyclosporine A in prolonging survival of murine islet cell and heart transplants across major histocompatibility barrier. | Transplant immunology 20120301 |
| Final height in a prospective trial of late steroid withdrawal after pediatric renal transplantation treated with cyclosporine and mizoribine. | Pediatric transplantation 20120201 |
| Developmental disruption of the serotonin system alters circadian rhythms. | Physiology & behavior 20120118 |
| The efficacy and safety of high-dose mizoribine in ABO-incompatible kidney transplantation using anti-CD20 and anti-CD25 antibody without splenectomy treatment. | Transplantation proceedings 20120101 |
| Excellent results with high-dose mizoribine combined with cyclosporine, corticosteroid, and basiliximab in renal transplant recipients: multicenter study in Japan. | Transplantation proceedings 20120101 |
| Experiences of high-dose mizoribine as antimetabolite immunosuppressants for kidney transplantation. | Transplantation proceedings 20120101 |
| Mizoribine suppresses proliferation of rat glomerular epithelial cells in culture and inhibits increase of monocyte chemoattractant protein-1 and macrophage inflammatory protein-2 stimulated by thrombin. | Biological & pharmaceutical bulletin 20120101 |
| A case of acute kidney injury with marked hyperuricemia during mizoribine administration. | Internal medicine (Tokyo, Japan) 20120101 |
| Mizoribine as sole immunosuppressive agent in islet xenotransplantation models: a candidate immunosuppressant causing no adverse effects on islets. | Cell transplantation 20120101 |
| Mizoribine treatment for antihistamine-resistant chronic autoimmune urticaria. | Dermatologic therapy 20120101 |
| Therapeutic effect of mizoribine on pemphigus vulgaris and pemphigus foliaceus. | Dermatologic therapy 20120101 |
| Chronopharmacology of mizoribine in collagen-induced arthritis rats. | Journal of pharmacological sciences 20120101 |
| [Therapy in IgA nephropathy--when and how to do it]. | Orvosi hetilap 20111218 |
| Population pharmacokinetics of mizoribine in adult recipients of renal transplantation. | Clinical and experimental nephrology 20111201 |
| Structures of Burkholderia thailandensis nucleoside kinase: implications for the catalytic mechanism and nucleoside selectivity. | Acta crystallographica. Section D, Biological crystallography 20111101 |
| [Treatment of rheumatic diseases: current status and future prospective. Topics: II. Immunosuppressant/antirheumatic drugs; 5. Leflunomide and mizoribine]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20111010 |
| Successful use of mizoribine in a patient with sarcoidosis and cutaneous vasculitis. | Acta dermato-venereologica 20110901 |
| Novel multidrug therapy for children with cyclosporine-resistant or -intolerant nephrotic syndrome. | Pediatric nephrology (Berlin, Germany) 20110801 |
| Enzymatic assay method for measuring mizoribine levels in serum. | Journal of bioscience and bioengineering 20110801 |
| Use of mizoribine in two patients with recalcitrant cutaneous polyarteritis nodosa. | Journal of the American Academy of Dermatology 20110601 |
| Efficacy and safety of mizoribine combined with losartan in the treatment of IgA nephropathy: a multicenter, randomized, controlled study. | The American journal of the medical sciences 20110501 |
| Unexpected occurrence of adrenal Cushing's syndrome in a patient with systemic lupus erythematosus. | Hypertension research : official journal of the Japanese Society of Hypertension 20110501 |
| Methylprednisolone pulse plus mizoribine in children with Henoch-Schoenlein purpura nephritis. | Clinical rheumatology 20110401 |
| Steroid treatment in patients with membranous nephropathy and hepatitis B virus surface antigenemia: a report of two cases. | Clinical and experimental nephrology 20110401 |
| Therapeutic efficacy of mizoribine for discoid lupus erythematosus with normalized frequency of circulating T helper 17 cells. | Clinical and experimental dermatology 20110401 |
| Single daily high-dose mizoribine therapy for children with steroid-dependent nephrotic syndrome prior to cyclosporine administration. | Pediatric nephrology (Berlin, Germany) 20110301 |
| Modulation in concentrative nucleoside transporters-mediated intestinal absorption of mizoribine, an immunosuppressive agent, in lipopolysaccharide-treated rats. | Die Pharmazie 20110301 |
| Methylprednisolone pulse therapy combined with mizoribine following tonsillectomy for immunoglobulin A nephropathy: clinical remission rate, steroid sparing effect, and maintenance of renal function. | Clinical and experimental nephrology 20110201 |
| Disappearance of glomerular IgA deposits in childhood IgA nephropathy showing diffuse mesangial proliferation after 2 years of combination/prednisolone therapy. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110101 |
| Evaluation of limited sampling designs to estimate maximal concentration and area under the curve of mizoribine in pediatric patients with renal disease. | Drug metabolism and pharmacokinetics 20110101 |
| [Two cases of rapidly progressive nephritic syndrome complicated with alcoholic liver cirrhosis]. | Nihon Jinzo Gakkai shi 20110101 |
| Cardiac AA amyloidosis in a patient with rheumatoid arthritis and systemic sclerosis: the therapeutic potential of biological reagents. | Scandinavian journal of rheumatology 20110101 |
| [Efficacy and safety of combination therapy with mizoribine and methotrexate for rheumatoid arthritis resistant with methotrexate]. | Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 20110101 |
| Effect of genetic polymorphisms of SLC28A1, ABCG2, and ABCC4 on bioavailability of mizoribine in healthy Japanese males. | Drug metabolism and pharmacokinetics 20110101 |
| [Secondary membranous nephropathy: The topics of membranous lupus nephritis]. | Nihon Jinzo Gakkai shi 20110101 |
| Successful treatment of chronic lupus myocarditis with prednisolone and mizoribine. | Modern rheumatology 20101201 |
| Low-dose steroid maintenance for renal transplant recipients. | Transplantation proceedings 20101201 |
| Effects of probenecid on the pharmacokinetics of mizoribine and co-administration of the two drugs in patients with nephrotic syndrome. | International journal of clinical pharmacology and therapeutics 20101101 |
| Mizoribine protects against bleomycin-induced lung injury. | Modern rheumatology 20101001 |
| Modelling the effects of inhibitors of guanine nucleotide synthesis: implications for studies of cellular differentiation pathways. | Biochemical Society transactions 20101001 |
| Efficacy of mizoribine for steroid-resistant membranoproliferative glomerulonephritis type III. | Nephrology (Carlton, Vic.) 20101001 |
| Mizoribine attenuates renal injury and macrophage infiltration in patients with severe lupus nephritis. | Clinical rheumatology 20100901 |
| Acute allograft renal failure with marked hyperuricemia developing during mizoribine administration: a case report with review of the literature. | Transplantation proceedings 20100901 |
| A sensitive and practical LC-MS/MS method for the determination of mizoribine in human serum and its bioequivalence study on Chinese healthy volunteers. | Yao xue xue bao = Acta pharmaceutica Sinica 20100901 |
| Increased intestinal absorption of mizoribine, an immunosuppressive agent, in cholestatic rats. | Die Pharmazie 20100701 |
| Mizoribine therapy in a patient with lupus nephritis: the association between mizoribine concentration and peritoneal dialysis. | Modern rheumatology 20100601 |
| Novel anticytomegalovirus activity of immunosuppressant mizoribine and its synergism with ganciclovir. | The Journal of pharmacology and experimental therapeutics 20100601 |
| Combination therapy with steroids and mizoribine in juvenile SLE: a randomized controlled trial. | Pediatric nephrology (Berlin, Germany) 20100501 |
| Impact of concentrative nucleoside transporter 1 gene polymorphism on oral bioavailability of mizoribine in stable kidney transplant recipients. | Basic & clinical pharmacology & toxicology 20100401 |
| Mizoribine reduces serum KL-6 levels in ANCA-associated vasculitis. | Clinical and experimental nephrology 20100401 |
| Study on intestinal absorption sites of mizoribine and ribavirin, substrates for concentrative nucleoside transporter(s), in rats. | European journal of pharmacology 20100225 |
| Successful use of mizoribine to treat recurrent corticosteroid-resistant palpable purpura in a patient with henoch-schonlein purpura nephritis. | Archives of dermatology 20100201 |
| Effect of mizoribine in children with inflammatory bowel disease. | Pediatrics international : official journal of the Japan Pediatric Society 20100201 |
| New algorithm (KAWAKAMI algorithm) to diagnose primary cutaneous vasculitis. | The Journal of dermatology 20100201 |
| Contrasting effects of steroids and mizoribine on macrophage activation and glomerular lesions in rat thy-1 mesangial proliferative glomerulonephritis. | American journal of nephrology 20100101 |
| Combinational effect of low-dose oral corticosteroid and mizoribine for ulcerative colitis in a patient with systemic sclerosis. | The Journal of dermatology 20100101 |
| The immunosuppressive drug mizoribine directly prevents podocyte injury in puromycin aminonucleoside nephrosis. | Nephron. Experimental nephrology 20100101 |
| Treatment of Mikulicz's disease with mizoribine. | Internal medicine (Tokyo, Japan) 20100101 |
| A case of Mikulicz's disease, IgG4-related plasmacytic syndrome, successfully treated by corticosteroid and mizoribine, followed by mizoribine alone. | Internal medicine (Tokyo, Japan) 20100101 |
| A novel target of mizoribine inhibiting mesangial cell proliferation: S phase kinase-associated protein 2. | American journal of nephrology 20100101 |
| Efficacy and safety of mizoribine by one single dose administration for patients with rheumatoid arthritis. | Internal medicine (Tokyo, Japan) 20100101 |
| [Minimal change nephrotic syndrome]. | Nihon Jinzo Gakkai shi 20100101 |
| [Focal segmental glomerulosclerosis (FSGS)]. | Nihon Jinzo Gakkai shi 20100101 |
| [Immunosuppressive therapies for refractory nephrotic syndrome]. | Nihon Jinzo Gakkai shi 20100101 |
| Protective effects of Mizoribine on Cyclosporine A nephropathy in rats. | Pediatric research 20091101 |
| Usefulness of initial histological features for stratifying Sjogren's syndrome responders to mizoribine therapy. | Rheumatology (Oxford, England) 20091001 |
| Remission of refractory minimal change nephrotic syndrome after basiliximab therapy. | Pediatric nephrology (Berlin, Germany) 20090701 |
| Iliopectineal bursitis associated with rapid destruction of a rheumatoid hip joint. | Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20090701 |
| Efficacy of mizoribine pulse therapy in patients with rheumatoid arthritis who show a reduced or insufficient response to infliximab. | Modern rheumatology 20090601 |
| Membrane transport mechanisms of mizoribine in the rat intestine and human epithelial LS180 cells. | Biological & pharmaceutical bulletin 20090401 |
| Mizoribine may suppress bone erosion in patients with rheumatoid arthritis by inhibiting osteoclastogenesis. | European journal of pharmacology 20090301 |
| Therapeutic effect of mizoribine on bullous pemphigoid associated with membranous nephropathy. | Journal of the American Academy of Dermatology 20090301 |
| [Renal involvement in connective tissue diseases]. | Nihon rinsho. Japanese journal of clinical medicine 20090301 |
| [Immunosuppressants]. | Nihon rinsho. Japanese journal of clinical medicine 20090301 |
| Mizoribine for renal sarcoidosis: effective steroid tapering and prevention of recurrence. | Pediatric nephrology (Berlin, Germany) 20090201 |
| Successful treatment of refractory polymyositis with the immunosuppressant mizoribine: case report. | Clinical rheumatology 20090201 |
| A case report of steroid-resistant antineutrophil cytoplasmic antibody-related vasculitis successfully treated by mizoribine in a hemodialysis patient. | Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20090201 |
| [ANCA associated vasculitis and PRGN]. | Nihon Jinzo Gakkai shi 20090101 |
| Mizoribine suppresses the progression of experimental peritoneal fibrosis in a rat model. | Nephron. Experimental nephrology 20090101 |
| Effects of low-dose mizoribine pulse therapy in combination with methotrexate in rheumatoid arthritis patients with an insufficient response to methotrexate. | Modern rheumatology 20090101 |
| Mizoribine: a new approach in the treatment of renal disease. | Clinical & developmental immunology 20090101 |
| A simple HPLC method for the quantification of mizoribine in human serum: pharmacokinetic applications. | Biomedical chromatography : BMC 20081101 |
| Mizoribine for relapsed proteinuria in an adult IgA nephropathy patient. | Clinical nephrology 20081101 |
| A novel enzymatic method for measuring mizoribine 5'-monophosphate levels in serum. | Journal of bioscience and bioengineering 20081101 |
| Pharmacokinetic study of mizoribine in child-onset glomerulonephritis. | Pediatrics international : official journal of the Japan Pediatric Society 20081001 |
| Hypocomplementemic urticarial vasculitis with Jaccoud's arthropathy and valvular heart disease: case report and review of the literature. | Lupus 20080901 |
| Conversion from mycophenolate mofetil to mizoribine for patients with positive polyomavirus type BK in urine. | Transplantation proceedings 20080901 |
| Oral mizoribine pulse therapy for steroid-dependent focal segmental glomerulosclerosis. | Clinical nephrology 20080601 |
| Characterization of intestinal absorption of mizoribine mediated by concentrative nucleoside transporters in rats. | European journal of pharmacology 20080531 |
| Combination therapy with mizoribine for severe childhood IgA nephropathy: a pilot study. | Pediatric nephrology (Berlin, Germany) 20080501 |
| Use of mizoribine as a rescue drug for steroid-resistant pediatric IgA nephropathy. | Pediatric nephrology (Berlin, Germany) 20080401 |
| Effect of oral mizoribine pulse therapy for frequently relapsing steroid-dependent nephrotic syndrome. | Clinical nephrology 20080301 |
| Non-corticosteroid treatment for nephrotic syndrome in children. | The Cochrane database of systematic reviews 20080123 |
| Mizoribine intermittent pulse protocol for induction therapy for systemic lupus erythematosus in children: an open-label pilot study with five newly diagnosed patients. | Clinical rheumatology 20080101 |
| A case of lupus nephritis improved after appropriately adjusting the dosage of mizoribine. | Modern rheumatology 20080101 |
| [Treatment of childhood IgA nephropathy]. | Nihon Jinzo Gakkai shi 20080101 |
| A sudden onset of diabetic ketoacidosis and acute pancreatitis after introduction of mizoribine therapy in a patient with rheumatoid arthritis. | Modern rheumatology 20080101 |
| Mizoribine treatment of young patients with severe lupus nephritis: a clinicopathologic study by the tohoku pediatric study group. | Nephron. Clinical practice 20080101 |
| Japanese experience of ABO-incompatible living kidney transplantation. | Transplantation 20071227 |
| Towards a molecular genetic system for the pathogenic fungus Paracoccidioides brasiliensis. | Fungal genetics and biology : FG & B 20071201 |
| Mechanism-of-action determination of GMP synthase inhibitors and target validation in Candida albicans and Aspergillus fumigatus. | Chemistry & biology 20071001 |
| Mizoribine corrects defective nephrin biogenesis by restoring intracellular energy balance. | Journal of the American Society of Nephrology : JASN 20070901 |
| Efficacy of steroid pulse, plasmapheresis, and mizoribine in a patient with focal segmental glomerulosclerosis. | Pediatric nephrology (Berlin, Germany) 20070801 |
| Long-term intermittent pulse therapy with mizoribine attenuates histologic progression in young patients with severe lupus nephritis: report of two patients. | Nephrology (Carlton, Vic.) 20070801 |
| Combination therapy of prednisolone and mizoribine improves cryoglobulinemic vasculitis with purpura and skin ulcers. | Clinical rheumatology 20070701 |
| Synthesis and biological evaluation of nucleoside analogues having 6-chloropurine as anti-SARS-CoV agents. | Bioorganic & medicinal chemistry letters 20070501 |
| Safety, tolerability and pharmacokinetics of higher-dose mizoribine in healthy male volunteers. | British journal of clinical pharmacology 20070401 |
| Prophylactic treatment of antibody-mediated rejection with high-dose mizoribine and pharmacokinetic study. | Transplant international : official journal of the European Society for Organ Transplantation 20070401 |
| Efficacy of single dose of oral mizoribine pulse therapy two times per week for frequently relapsing nephrotic syndrome. | Journal of nephrology 20070101 |
| Mizoribine therapy for patients with lupus nephritis: the association between peak mizoribine concentration and clinical efficacy. | Modern rheumatology 20070101 |
| Efficacy and safety of mizoribine for the treatment of Sjögren's syndrome: a multicenter open-label clinical trial. | Modern rheumatology 20070101 |
| Population pharmacokinetics of higher-dose mizoribine in healthy male volunteers. | Biological & pharmaceutical bulletin 20061201 |
| Mizoribine oral pulse therapy for a patient with polyarticular juvenile idiopathic arthritis. | Pediatrics international : official journal of the Japan Pediatric Society 20061201 |
| Effects of mizoribine on MHC-restricted exogenous antigen presentation in dendritic cells. | Archives of pharmacal research 20061201 |
| Comparison of tacrolimus and mizoribine in a randomized, double-blind controlled study in patients with rheumatoid arthritis. | The Journal of rheumatology 20061101 |
| Changing mizoribine administration from three divided doses to one single dose induced remission of relapsed membranous nephropathy. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060801 |
| Enhancement of the infectivity of SARS-CoV in BALB/c mice by IMP dehydrogenase inhibitors, including ribavirin. | Antiviral research 20060801 |
| Combination effect of mycophenolate mofetil with mizoribine on cell proliferation assays and in a mouse heart transplantation model. | Transplantation 20060727 |
| Long-term mizoribine intermittent pulse therapy for young patients with flare of lupus nephritis. | Pediatric nephrology (Berlin, Germany) 20060701 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Mizoribine induces remission of relapsed ANCA-associated renal vasculitis. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060401 |
| High-dose mizoribine treatment for adolescents with systemic lupus erythematosus. | Pediatrics international : official journal of the Japan Pediatric Society 20060401 |
| The nucleotide derivatives inosine and inosinic acid inhibit intestinal absorption of mizoribine in rats. | European journal of pharmacology 20060215 |
| [Molecular action mechanisms of the therapeutic agents for kidney diseases: Immunosuppressants]. | Nihon rinsho. Japanese journal of clinical medicine 20060201 |
| Stevens-Johnson syndrome induced by mizoribine in a patient with systemic lupus erythematosus. | Modern rheumatology 20060101 |
| [Beneficial and adverse effects of high-dosage MZR therapy in the management of children with frequently relapsing nephrotic syndrome]. | Nihon Jinzo Gakkai shi 20060101 |
| Acceptability and usefulness of mizoribine in the management of rheumatoid arthritis in methotrexate-refractory patients and elderly patients, based on analysis of data from a large-scale observational cohort study. | Modern rheumatology 20060101 |
| Revival of effective and safe high-dose mizoribine for the kidney transplantation. | Clinical transplantation 20060101 |
| High-dose mizoribine therapy for childhood-onset frequently relapsing steroid-dependent nephrotic syndrome with cyclosporin nephrotoxicity. | Pediatric nephrology (Berlin, Germany) 20051201 |
| Induction therapy with low-dose intravenous cyclophosphamide, oral mizoribine, and steroids for severe lupus nephritis in children. | Pediatric nephrology (Berlin, Germany) 20051001 |
| Oral mizoribine pulse therapy for patients with steroid-resistant and frequently relapsing steroid-dependent nephrotic syndrome. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20051001 |
| Mizoribine reduces renal injury and macrophage infiltration in non-insulin-dependent diabetic rats. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050801 |
| Effects of long-term treatment with mizoribine in patients with proliferative lupus nephritis. | Clinical nephrology 20050701 |
| Mizoribine decreases urinary protein excretion in two patients with IgA nephropathy. | Clinical nephrology 20050701 |
| Inhibitory effect of mizoribine and ribavirin on the replication of severe acute respiratory syndrome (SARS)-associated coronavirus. | Antiviral research 20050601 |
| Implication of the peak serum level of mizoribine for control of the serum anti-dsDNA antibody titer in patients with lupus nephritis. | Clinical nephrology 20050601 |
| Mizoribine inhibits hepatitis C virus RNA replication: effect of combination with interferon-alpha. | Biochemical and biophysical research communications 20050513 |
| Immunosuppressive efficacy of mycophenolate mofetil when compared with azathioprine and mizoribine against peripheral lymphocytes from renal transplant recipients. | Transplant international : official journal of the European Society for Organ Transplantation 20050501 |
| [Mizoribine]. | Nihon rinsho. Japanese journal of clinical medicine 20050501 |
| Potential value of high-dose mizoribine as rescue therapy for ongoing acute humoral rejection. | Transplant international : official journal of the European Society for Organ Transplantation 20050401 |
| A prospective trial of steroid withdrawal after renal transplantation treated with cyclosporine and mizoribine in children: results obtained between 1990 and 2003. | Pediatric transplantation 20050401 |
| Mizoribine-induced rhabdomyolysis in a rheumatoid arthritis patient receiving bezafibrate treatment. | The American journal of the medical sciences 20050401 |
| The functional basis of mycophenolic acid resistance in Candida albicans IMP dehydrogenase. | The Journal of biological chemistry 20050325 |
| Mizoribine in combination therapy with tacrolimus for living donor renal transplantation: analysis of a nationwide study in Japan. | Transplantation proceedings 20050301 |
| Mizoribine oral pulse therapy for steroid-dependent nephrotic syndrome. | Pediatric nephrology (Berlin, Germany) 20050101 |
| Mizoribine pulse therapy for a pediatric patient with steroid-resistant nephrotic syndrome. | The Tohoku journal of experimental medicine 20050101 |
| Mizoribine-mediated apoptotic signaling pathway in human T-Cell line. | Transplantation proceedings 20050101 |
| A simple determination of mizoribine in human plasma by liquid chromatography with UV detection. | Journal of AOAC International 20050101 |
| [Treatment guidelines for the idiopathic nephrotic syndrome in children]. | Nihon Jinzo Gakkai shi 20050101 |
| Inhibition of bovine viral diarrhea virus (BVDV) by mizoribine: synergistic effect of combination with interferon-alpha. | Antiviral research 20041201 |
| Mizoribine for the treatment of lupus nephritis in children and adolescents. | Clinical nephrology 20041201 |
| Pharmacokinetic study of mizoribine in an adolescent with lupus nephritis. | Pediatrics international : official journal of the Japan Pediatric Society 20041001 |
| [Immunosuppressive therapy for nephrotic syndrome and strategy for adverse side effects from that therapy]. | Nihon rinsho. Japanese journal of clinical medicine 20041001 |
| Efficacy of mizoribine in the treatment of systemic lupus erythematosus in children. | Pediatrics international : official journal of the Japan Pediatric Society 20040801 |
| Mizoribine pulse therapy for patients with flares of lupus nephritis: a 1-year observation. | Clinical nephrology 20040801 |
| Treatment with the purine synthesis inhibitor mizoribine for ANCA-associated renal vasculitis. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20040701 |
| [Angiotensin type 1 receptor blocker reduced proteinuria in patients of focal glomerular sclerosis]. | Nihon Jinzo Gakkai shi 20040701 |
| D-penicillamine-induced pemphigus successfully treated with combination therapy of mizoribine and prednisolone. | The Journal of dermatological treatment 20040701 |
| A randomized open-label comparative study of conventional therapy versus mizoribine onlay therapy in patients with steroid-resistant nephrotic syndrome (postmarketing survey). | Clinical and experimental nephrology 20040601 |
| [A case of rheumatoid arthritis/Sjogren's syndrome with acute renal failure due to hyperuricemia associated with mizoribine therapy]. | Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 20040601 |
| Substitution of the conserved Arg-Tyr dyad selectively disrupts the hydrolysis phase of the IMP dehydrogenase reaction. | Biochemistry 20040420 |
| Cofactor mimics as selective inhibitors of NAD-dependent inosine monophosphate dehydrogenase (IMPDH)--the major therapeutic target. | Current medicinal chemistry 20040401 |
| A prospective trial of steroid withdrawal after renal transplantation in children: results obtained 1990 and 2002. | Transplantation proceedings 20040301 |
| Efficacy of prednisolone and mizoribine therapy for diffuse IgA nephropathy. | American journal of nephrology 20040101 |
| Allochronic overlapping malignancies after renal transplantation in a patient with p53 gene mutation: report of a case. | Surgery today 20040101 |
| Efficacy of multidrug therapy combined with mizoribine in children with diffuse IgA nephropathy in comparison with multidrug therapy without mizoribine and with methylprednisolone pulse therapy. | American journal of nephrology 20040101 |
| Mizoribine oral pulse therapy for patients with disease flare of lupus nephritis. | Clinical nephrology 20031201 |
| Comparison of antiproteinuric effects of two different combination therapies in children with IgA nephropathy. | Clinical and experimental nephrology 20031201 |
| Mizoribine oral pulse therapy for a patient with severe lupus nephritis. | Pediatrics international : official journal of the Japan Pediatric Society 20030801 |
| The immunosuppressive agent mizoribine monophosphate forms a transition state analogue complex with inosine monophosphate dehydrogenase. | Biochemistry 20030204 |
| [IMP dehydrogenase]. | Nihon rinsho. Japanese journal of clinical medicine 20030101 |
| Effect of conversion from cyclosporine A to mizoribine on transplant arteriosclerosis in rat aortic allograft models. | Microsurgery 20030101 |
| Metabolic enzymes as targets for 14-3-3 proteins. | Plant molecular biology 20021201 |
| Acute vascular and interstitial rejection following renal allograft transplantation in dogs. | The Journal of veterinary medical science 20021201 |
| [Guidelines for the management of refractory nephrotic syndrome--from investigations between 1997 and 2001--research project team for progressive renal lesions in the Ministry of Health, Labor and Welfare, Japan]. | Nihon Jinzo Gakkai shi 20021201 |
| Inhibitors of the IMPDH enzyme as potential anti-bovine viral diarrhoea virus agents. | Antiviral chemistry & chemotherapy 20021101 |
| [A case of acute renal failure with marked hyperuricemia developing during mizoribine administration]. | Nihon Jinzo Gakkai shi 20021001 |
| Synergistic effect of high-dose mizoribine and low-dose tacrolimus on renal allograft survival in nonhuman primates. | Transplantation proceedings 20020801 |
| Reversible segmental stenotic lesion of subclavian artery in an 8-year-old girl: an atypical Takayasu's arteritis? | Clinical rheumatology 20020801 |
| Effect of mizoribine on IL-6 release by peripheral blood mononuclear cells. | Nephron 20020701 |
| Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
| Mizoribine: mode of action and effects in clinical use. | Pediatrics international : official journal of the Japan Pediatric Society 20020401 |
| Mizoribine as an effective combined maintenance therapy with prednisolone in child-onset systemic lupus erythematosus. | Pediatrics international : official journal of the Japan Pediatric Society 20020401 |
| Nephrotic syndrome and mizoribine in children. | Pediatrics international : official journal of the Japan Pediatric Society 20020401 |
| Mizoribine treatment for childhood IgA nephropathy. | Pediatrics international : official journal of the Japan Pediatric Society 20020401 |
| Role of mizoribine in renal transplantation. | Pediatrics international : official journal of the Japan Pediatric Society 20020401 |
| Identification of heat shock protein 60 as a molecular mediator of alpha 3 beta 1 integrin activation. | Cancer research 20020301 |
| Potentiating effect of mizoribine on the anti-herpes virus activity of acyclovir. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20020101 |
| Mizoribine ameliorates the tubulointerstitial fibrosis of obstructive nephropathy. | Nephron 20011001 |
| [Systemic lupus erythematosus presenting as a brainstem infarction and hemorrhage during treating retroperitoneal abscess: a case report]. | Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20010701 |
| Effect of mizoribine on serum IgE concentration in patients with IgA nephropathy. | Nephron 20010201 |
| The antiproliferative effect of mizoribine on rheumatoid synovial fibroblast mediated by induction of apoptosis. | The Kobe journal of medical sciences 20010201 |
| Inosine-5'-monophosphate dehydrogenase is required for mitogenic competence of transformed pancreatic beta cells. | Endocrinology 20010101 |
| The efficacy and safety of mizoribine in living donor kidney transplantation: a 24-week, open-label, prospective study (phase III clinical trial). | Transplantation proceedings 20010101 |
| Long-term results of spousal renal donor transplants with donor-specific blood transfusions. | Transplantation proceedings 20010101 |
| Dosing time-dependent pharmacological effects of anti-metabolites for rat cardiac graft. | Research communications in molecular pathology and pharmacology 20010101 |
| Mizoribine in steroid-dependent nephrotic syndrome of childhood. | Pediatric nephrology (Berlin, Germany) 19971001 |
| Mizoribine reduces urinary protein excretion in rats given puromycin aminonucleoside. | American journal of nephrology 19960101 |
| [Comparison of the effects of various immunosuppressive drugs on subrenal capsule assay (SRC assay)]. | Hinyokika kiyo. Acta urologica Japonica 19900701 |
| [Suppressive effect of mizoribine on progression of bovine serum albumin nephritis in mice]. | Nihon Jinzo Gakkai shi 19870401 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.