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5086-74-8 | Tetramisole hydrochloride
CAS No: 5086-74-8 Catalog No: AG003UQJ MDL No:MFCD00005536
Product Description
Catalog Number:
AG003UQJ
Chemical Name:
Tetramisole hydrochloride
CAS Number:
5086-74-8
Molecular Formula:
C11H13ClN2S
Molecular Weight:
240.7523
MDL Number:
MFCD00005536
IUPAC Name:
6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole;hydrochloride
InChI:
InChI=1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H
InChI Key:
LAZPBGZRMVRFKY-UHFFFAOYSA-N
SMILES:
C1CN2C(=NC(C2)c2ccccc2)S1.Cl
EC Number:
225-799-5
Properties
Complexity:
246
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
240.049g/mol
Formal Charge:
0
Heavy Atom Count:
15
Hydrogen Bond Acceptor Count:
2
Hydrogen Bond Donor Count:
1
Isotope Atom Count:
0
Molecular Weight:
240.749g/mol
Monoisotopic Mass:
240.049g/mol
Rotatable Bond Count:
1
Topological Polar Surface Area:
40.9A^2
Undefined Atom Stereocenter Count:
1
Undefined Bond Stereocenter Count:
0
Literature
| Title | Journal |
|---|---|
| Susceptibility assay of Haemonchus contortus to commonly used anthelmintics in Jimma, southwest Ethiopia. | Tropical animal health and production 20121001 |
| Origin of enantioselectivity in benzotetramisole-catalyzed dynamic kinetic resolution of azlactones. | Organic letters 20120706 |
| Multi-organ failure following severe cocaine-tetramisole intoxication in a body-packer. | Anaesthesia and intensive care 20120501 |
| Determination of phenyltetrahydroimidazothiazole enantiomers (Levamisole/Dexamisole) in illicit cocaine seizures and in the urine of cocaine abusers via chiral capillary gas chromatography-flame-ionization detection: clinical and forensic perspectives. | Journal of analytical toxicology 20120301 |
| [Development of novel methods for preparing chiral non-steroidal anti-inflammatory drugs (NSAIDs) by asymmetric esterification]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20120101 |
| Kinetic resolution of α-substituted alkanoic acids promoted by homobenzotetramisole. | Chemistry (Weinheim an der Bergstrasse, Germany) 20110926 |
| Kinetic resolution of N-acyl-β-lactams via benzotetramisole-catalyzed enantioselective alcoholysis. | Journal of the American Chemical Society 20110907 |
| Silylation-based kinetic resolution of monofunctional secondary alcohols. | Organic letters 20110805 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| Kinetic resolution of racemic alpha-arylalkanoic acids with achiral alcohols via the asymmetric esterification using carboxylic anhydrides and acyl-transfer catalysts. | Journal of the American Chemical Society 20100825 |
| Benzotetramisole-catalyzed dynamic kinetic resolution of azlactones. | Organic letters 20100219 |
| Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. | Nature chemical biology 20091001 |
| Homobenzotetramisole: an effective catalyst for kinetic resolution of aryl-cycloalkanols. | Organic letters 20080320 |
| Potentiometric sensor for the high throughput determination of tetramisole hydrochloride. | Combinatorial chemistry & high throughput screening 20070801 |
| Characterization of an ecto-5'-nucleotidase (EC 3.1.3.5) activity in intact trophozoites of Trichomonas gallinae. | Veterinary parasitology 20070131 |
| Kinetic resolution of propargylic alcohols catalyzed by benzotetramisole. | Organic letters 20061012 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Benzotetramisole: a remarkably enantioselective acyl transfer catalyst. | Organic letters 20060330 |
| Neurobehavioral effects of tetramisole in mice. | Neurotoxicology 20060301 |
| Anthelmintic resistance of nematode parasites of small ruminants in eastern Ethiopia: exploitation of refugia to restore anthelmintic efficacy. | Veterinary parasitology 20060218 |
| A CFTR chloride channel activator prevents HrpN(ea)-induced cell death in Arabidopsis thaliana suspension cells. | Plant physiology and biochemistry : PPB 20050601 |
| Enantioseparations by capillary electro-chromatography: differences exhibited by normal- and reversed-phase versions of polysaccharide stationary phases. | Electrophoresis 20040801 |
| A generic assay for phosphate-consuming or -releasing enzymes coupled on-line to liquid chromatography for lead finding in natural products. | Analytical biochemistry 20030501 |
| Facile colorimetric methods for the quantitative determination of tetramisole hydrochloride. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20021001 |
| Necessity of enzymatic activity of alkaline phosphatase for mineralization of osteoblastic cells. | Japanese journal of pharmacology 20020301 |
| Kinetic comparison of tissue non-specific and placental human alkaline phosphatases expressed in baculovirus infected cells: application to screening for Down's syndrome. | BMC biochemistry 20020101 |
| Anthelmintic resistance on an organized sheep farm in India. | Tropical animal health and production 20010701 |
| Psychopharmacological profile of dexamisole. | Polish journal of pharmacology and pharmacy 19800101 |
| Effects of parasitism on selected physiological measurements of the cottontail rabbit. | Journal of wildlife diseases 19741001 |
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