200,000+ products from a single source!
sales@angenechem.com
Home > Other Building Blocks > 5080-50-2
5080-50-2 | (S);-3-Acetoxy-4-(trimethylammonio);butanoate hydrochloride
CAS No: 5080-50-2 Catalog No: AG003TFG MDL No:MFCD00082230
Product Description
Catalog Number:
AG003TFG
Chemical Name:
(S);-3-Acetoxy-4-(trimethylammonio);butanoate hydrochloride
CAS Number:
5080-50-2
Molecular Formula:
C9H18ClNO4
Molecular Weight:
239.6965
MDL Number:
MFCD00082230
IUPAC Name:
[(2R)-2-acetyloxy-3-carboxypropyl]-trimethylazanium;chloride
InChI:
InChI=1S/C9H17NO4.ClH/c1-7(11)14-8(5-9(12)13)6-10(2,3)4;/h8H,5-6H2,1-4H3;1H/t8-;/m1./s1
InChI Key:
JATPLOXBFFRHDN-DDWIOCJRSA-N
SMILES:
[O-]C(=O)C[C@@H](C[N+](C)(C)C)OC(=O)C.Cl
EC Number:
610-570-8
UNII:
NDW10MX58T
NSC Number:
747431
Properties
Complexity:
219
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2
Defined Atom Stereocenter Count:
1
Defined Bond Stereocenter Count:
0
Exact Mass:
239.092g/mol
Formal Charge:
0
Heavy Atom Count:
15
Hydrogen Bond Acceptor Count:
5
Hydrogen Bond Donor Count:
1
Isotope Atom Count:
0
Molecular Weight:
239.696g/mol
Monoisotopic Mass:
239.092g/mol
Rotatable Bond Count:
6
Topological Polar Surface Area:
63.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
| Title | Journal |
|---|---|
| Acetyl L-carnitine targets adenosine triphosphate synthase in protecting zebrafish embryos from toxicities induced by verapamil and ketamine: An in vivo assessment. | Journal of applied toxicology : JAT 20170201 |
| Effect of Acetyl-L-Carnitine on Antioxidant Status, Lipid Peroxidation, and Oxidative Damage of Arsenic in Rat. | Biological trace element research 20160501 |
| Prophylactic and Therapeutic Potential of Acetyl-L-carnitine against Acetaminophen-Induced Hepatotoxicity in Mice. | Journal of biochemical and molecular toxicology 20160101 |
| Triptolide disrupts fatty acids and peroxisome proliferator-activated receptor (PPAR) levels in male mice testes followed by testicular injury: A GC-MS based metabolomics study. | Toxicology 20151002 |
| Acetyl-L-carnitineameliorates mitochondrial damage and apoptosis following spinal cord injury in rats. | Neuroscience letters 20150914 |
| ROS act as an upstream signal to mediate cadmium-induced mitophagy in mouse brain. | Neurotoxicology 20150101 |
| Skeletal muscle ¹H MRSI before and after prolonged exercise. II. visibility of free carnitine. | Magnetic resonance in medicine 20121101 |
| Water-soluble cationic derivatives of indirubin, the active anticancer component from Indigo naturalis. | Chemistry & biodiversity 20121001 |
| Dietary supplementation with acetyl-l-carnitine in seizure treatment of pentylenetetrazole kindled mice. | Neurochemistry international 20120901 |
| Effect of short- and long-term treatment with valproate on carnitine homeostasis in humans. | Therapeutic drug monitoring 20120801 |
| Identification of human plasma metabolites exhibiting time-of-day variation using an untargeted liquid chromatography-mass spectrometry metabolomic approach. | Chronobiology international 20120801 |
| Preserving mitochondrial function prevents the proteasomal degradation of GTP cyclohydrolase I. | Free radical biology & medicine 20120715 |
| Neurophysiological and morphological responses to treatment with acetyl-L-carnitine in a sciatic nerve injury model: preliminary data. | The Journal of hand surgery, European volume 20120701 |
| The acetylcholinesterase inhibitors competitively inhibited an acetyl L-carnitine transport through the blood-brain barrier. | Neurochemical research 20120701 |
| Chronic acetyl-L-carnitine alters brain energy metabolism and increases noradrenaline and serotonin content in healthy mice. | Neurochemistry international 20120701 |
| Re: Karsidag S, Akcal A, Sahin S, et al. Neurophysiological and morphological responses to treatment with acetyl-L-carnitine in a sciatic nerve injury model: preliminary data. J Hand Surg Eur. 2012, 37: 529-536. | The Journal of hand surgery, European volume 20120701 |
| Acetyl-L-carnitine treatment following spinal cord injury improves mitochondrial function correlated with remarkable tissue sparing and functional recovery. | Neuroscience 20120517 |
| Carnitine for fatigue in multiple sclerosis. | The Cochrane database of systematic reviews 20120516 |
| Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility. | Cell metabolism 20120502 |
| Drug treatment for spinal muscular atrophy types II and III. | The Cochrane database of systematic reviews 20120418 |
| Acetyl-L-carnitine-mediated neuroprotection during hypoxia is attributed to ERK1/2-Nrf2-regulated mitochondrial biosynthesis. | Hippocampus 20120401 |
| Inhibition of OCTN2-mediated transport of carnitine by etoposide. | Molecular cancer therapeutics 20120401 |
| Acetyl-L-carnitine activates the peroxisome proliferator-activated receptor-γ coactivators PGC-1α/PGC-1β-dependent signaling cascade of mitochondrial biogenesis and decreases the oxidized peroxiredoxins content in old rat liver. | Rejuvenation research 20120401 |
| Biochemical and genetic alterations of oxidant/antioxidant status of the brain in rats treated with dexamethasone: protective roles of melatonin and acetyl-L-carnitine. | Journal of physiology and biochemistry 20120301 |
| The human OCTN1 (SLC22A4) reconstituted in liposomes catalyzes acetylcholine transport which is defective in the mutant L503F associated to the Crohn's disease. | Biochimica et biophysica acta 20120301 |
| The cycling of acetyl-coenzyme A through acetylcarnitine buffers cardiac substrate supply: a hyperpolarized 13C magnetic resonance study. | Circulation. Cardiovascular imaging 20120301 |
| Carnitine derivatives: clinical usefulness. | Current opinion in gastroenterology 20120301 |
| In vivo clinical measures of intermediary metabolism are inadequate: can a new magnetic resonance spectroscopy technology do better? | Circulation. Cardiovascular imaging 20120301 |
| Acetyl-L-carnitine and α-lipoic acid affect rotenone-induced damage in nigral dopaminergic neurons of rat brain, implication for Parkinson's disease therapy. | Pharmacology, biochemistry, and behavior 20120101 |
| Semen quality in patients with Chlamydia trachomatis genital infection treated concurrently with prulifloxacin and a phytotherapeutic agent. | Journal of andrology 20120101 |
| Substrate oxidation and cardiac performance during exercise in disorders of long chain fatty acid oxidation. | Molecular genetics and metabolism 20120101 |
| Selective degeneration of synapses in the dorsal cochlear nucleus of chinchilla following acoustic trauma and effects of antioxidant treatment. | Hearing research 20120101 |
| Protective effects of acetyl-L-carnitine on neurodegenarative changes in chronic cerebral ischemia models and learning-memory impairment in aged rats. | Archives of pharmacal research 20120101 |
| Acetyl-L-carnitine supplementation reverses the age-related decline in carnitine palmitoyltransferase 1 (CPT1) activity in interfibrillar mitochondria without changing the L-carnitine content in the rat heart. | Mechanisms of ageing and development 20120101 |
| Neuroprotective effects of pre-treatment with l-carnitine and acetyl-L-carnitine on ischemic injury in vivo and in vitro. | International journal of molecular sciences 20120101 |
| Neuroprotective effects of N-acetyl-cysteine and acetyl-L-carnitine after spinal cord injury in adult rats. | PloS one 20120101 |
| Deciphering the potential efficacy of acetyl-L-carnitine (ALCAR) in maintaining connexin-mediated lenticular homeostasis. | Molecular vision 20120101 |
| Stability of carboplatin, paclitaxel, and docetaxel with acetyl-l-carnitine during simulated Y-site administration. | International journal of pharmaceutical compounding 20120101 |
| Stability of acetyl-1-carnitine in 5% dextrose using a high-performance liquid chromatography-mass spectrometry times 2 method. | International journal of pharmaceutical compounding 20120101 |
| Drug treatment for spinal muscular atrophy types II and III. | The Cochrane database of systematic reviews 20111207 |
| Acetyl-L-carnitine prevents carbon tetrachloride-induced oxidative stress in various tissues of Wistar rats. | Journal of physiology and biochemistry 20111201 |
| Acetyl-L-carnitine improves cognitive functions in severe hepatic encephalopathy: a randomized and controlled clinical trial. | Metabolic brain disease 20111201 |
| Acetyl-L-carnitine attenuates homocysteine-induced Alzheimer-like histopathological and behavioral abnormalities. | Rejuvenation research 20111201 |
| Quantitative tandem mass spectrometric imaging of endogenous acetyl-L-carnitine from piglet brain tissue using an internal standard. | Analytical chemistry 20111115 |
| Antidepressant-like effect of artemin in mice: a mechanism for acetyl-L-carnitine activity on depression. | Psychopharmacology 20111101 |
| The nerve injury and the dying neurons: diagnosis and prevention. | The Journal of hand surgery, European volume 20111101 |
| Protective effect of acetyl-l-carnitine and α-lipoic acid against the acute toxicity of diepoxybutane to human lymphocytes. | Toxicology 20111028 |
| Rat liver mitochondrial proteome: changes associated with aging and acetyl-L-carnitine treatment. | Journal of proteomics 20111019 |
| Stabilization of superoxide dismutase by acetyl-l-carnitine in human brain endothelium during alcohol exposure: novel protective approach. | Free radical biology & medicine 20111015 |
| Acetyl-L-carnitine ameliorates spatial memory deficits induced by inhibition of phosphoinositol-3 kinase and protein kinase C. | Journal of neurochemistry 20110901 |
| Regular endurance exercise improves the diminished hepatic carnitine status in mice fed a high-fat diet. | Molecular nutrition & food research 20110901 |
| The supplementation of acetyl-L-carnitine decreases fatigue and increases quality of life in patients with hepatitis C treated with pegylated interferon-α 2b plus ribavirin. | Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20110901 |
| Effect of in vivo L-acetylcarnitine administration on ATP-ases enzyme systems of synaptic plasma membranes from rat cerebral cortex. | Neurochemical research 20110801 |
| Modulation of myelin basic protein gene expression by acetyl-L-carnitine. | Molecular neurobiology 20110801 |
| Complementary medicines (herbal and nutritional products) in the treatment of Attention Deficit Hyperactivity Disorder (ADHD): a systematic review of the evidence. | Complementary therapies in medicine 20110801 |
| [Roles of PYK2 and caveolin-1 in alcoholic cardiomyopathy and the effect of drug intervention]. | Zhonghua yi xue za zhi 20110614 |
| Role of mitochondria in the maintenance of platelet function during in vitro storage. | Transfusion medicine (Oxford, England) 20110601 |
| Acetyl-l-Carnitine in the treatment of anhedonia, melancholic and negative symptoms in alcohol dependent subjects. | Progress in neuro-psychopharmacology & biological psychiatry 20110601 |
| Acetyl-L-carnitine as an adjunctive therapy in the treatment of attention-deficit/hyperactivity disorder in children and adolescents: a placebo-controlled trial. | Child psychiatry and human development 20110601 |
| Acetyl-L-carnitine reduces depression and improves quality of life in patients with minimal hepatic encephalopathy. | Scandinavian journal of gastroenterology 20110601 |
| Activation of AMP-activated protein kinase prevents lipotoxicity in retinal pericytes. | Investigative ophthalmology & visual science 20110501 |
| Acetyl-L-carnitine (ALC) administration positively affects reproductive axis in hypogonadotropic women with functional hypothalamic amenorrhea. | Journal of endocrinological investigation 20110401 |
| Inhibitory effects of alcohol on glucose transport across the blood-brain barrier leads to neurodegeneration: preventive role of acetyl-L: -carnitine. | Psychopharmacology 20110401 |
| Roles of reactive oxygen species and mitochondria in cadmium-induced injury of liver cells. | Toxicology and industrial health 20110401 |
| Chronic pretreatment with acetyl-L-carnitine and ±DL-α-lipoic acid protects against acute glutamate-induced neurotoxicity in rat brain by altering mitochondrial function. | Neurotoxicity research 20110201 |
| Neuroprotection by acetyl-L-carnitine after traumatic injury to the immature rat brain. | Developmental neuroscience 20110201 |
| Cisplatin-induced cardiotoxicity: Mechanisms and cardioprotective strategies. | European journal of pharmacology 20110110 |
| Noninvasive assessment of exercise-related intramyocellular acetylcarnitine in euglycemia and hyperglycemia in patients with type 1 diabetes using ¹H magnetic resonance spectroscopy: a randomized single-blind crossover study. | Diabetes care 20110101 |
| Biochemical and pharmacological effects of mitoxantrone and acetyl-L-carnitine in mice with a solid form of Ehrlich tumour. | Chemotherapy 20110101 |
| Critical update for the clinical use of L-carnitine analogs in cardiometabolic disorders. | Vascular health and risk management 20110101 |
| Evaluation of the effect of acetyl L-carnitine on experimental cisplatin ototoxicity and neurotoxicity. | Chemotherapy 20110101 |
| Methamphetamine inhibits the glucose uptake by human neurons and astrocytes: stabilization by acetyl-L-carnitine. | PloS one 20110101 |
| [Acetyl-L-carnitine (carnicetine) in the treatment of early stages of Alzheimer's disease and vascular dementia]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101 |
| Acetyl-L-carnitine protects neuronal function from alcohol-induced oxidative damage in the brain. | Free radical biology & medicine 20101130 |
| Effects of acetyl-L-carnitine and oxfenicine on aorta stiffness in diabetic rats. | European journal of clinical investigation 20101101 |
| Effect of antioxidants on mitochondrial function in HIV-1-related lipoatrophy: a pilot study. | AIDS research and human retroviruses 20101101 |
| Cisplatin-induced downregulation of OCTN2 affects carnitine wasting. | Clinical cancer research : an official journal of the American Association for Cancer Research 20101001 |
| Nerve regeneration in neuropathic pain. | Pain medicine (Malden, Mass.) 20101001 |
| [Treatment with carnitine, acetyl carnitine, L-arginine and ginseng improves sperm motility and sexual health in men with asthenopermia]. | Minerva urologica e nefrologica = The Italian journal of urology and nephrology 20100901 |
| Malonylcarnitine in newborns with non-syndromic cleft lip with or without cleft palate. | International journal of oral science 20100901 |
| Assessment of 3-nitropropionic acid-evoked peripheral neuropathy in rats: neuroprotective effects of acetyl-l-carnitine and resveratrol. | Neuroscience letters 20100816 |
| AMPK attenuates bupivacaine-induced neurotoxicity. | Journal of dental research 20100801 |
| Metabolism of acetyl-L-carnitine for energy and neurotransmitter synthesis in the immature rat brain. | Journal of neurochemistry 20100801 |
| Acetyl-L-carnitine protects yeast cells from apoptosis and aging and inhibits mitochondrial fission. | Aging cell 20100801 |
| Metabolic approach to the enhancement of antitumor effect of chemotherapy: a key role of acetyl-L-carnitine. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100801 |
| Behavior of acetyl-L-carnitine injections (Nicetile fiale) with different drugs used for combined therapy. | Advances in therapy 20100801 |
| Acetyl-l-carnitine increases nerve regeneration and target organ reinnervation - a morphological study. | Journal of plastic, reconstructive & aesthetic surgery : JPRAS 20100701 |
| Acetyl-L-carnitine ameliorates mitochondrial dysfunction following contusion spinal cord injury. | Journal of neurochemistry 20100701 |
| Carnitine palmitoyltransferase 2 deficiency: the time-course of blood and urinary acylcarnitine levels during initial L-carnitine supplementation. | The Tohoku journal of experimental medicine 20100701 |
| Acetyl-L-carnitine improves aged brain function. | Geriatrics & gerontology international 20100701 |
| Acetyl-L-carnitine increases artemin level and prevents neurotrophic factor alterations during neuropathy. | Neuroscience 20100602 |
| Oxidative stress and cognitive longevity. | Nutrition (Burbank, Los Angeles County, Calif.) 20100601 |
| Oral acetyl-L-carnitine therapy and insulin resistance. | Hypertension (Dallas, Tex. : 1979) 20100601 |
| Newborn screening for methylmalonic aciduria by tandem mass spectrometry: 7 years' experience from two centers in Taiwan. | Journal of the Chinese Medical Association : JCMA 20100601 |
| Acetyl-L-carnitine reduces the infarct size and striatal glutamate outflow following focal cerebral ischemia in rats. | Annals of the New York Academy of Sciences 20100601 |
| Managing diabetic peripheral neuropathic pain in primary care. | The Journal of family practice 20100501 |
| Transcriptional regulation of type-2 metabotropic glutamate receptors: an epigenetic path to novel treatments for chronic pain. | Trends in pharmacological sciences 20100401 |
| Ubisol-Aqua: coenzyme Q10 prevents antiretroviral toxic neuropathy in an in vitro model. | Current HIV research 20100401 |
| Differential metabolomics for quantitative assessment of oxidative stress with strenuous exercise and nutritional intervention: thiol-specific regulation of cellular metabolism with N-acetyl-L-cysteine pretreatment. | Analytical chemistry 20100401 |
| Acetyl-L-carnitine. Monograph. | Alternative medicine review : a journal of clinical therapeutic 20100401 |
| Regulatory effect of acetyl-l-carnitine on expression of lenticular antioxidant and apoptotic genes in selenite-induced cataract. | Chemico-biological interactions 20100330 |
| Protective effects of acetyl-L-carnitine on cisplatin cytotoxicity and oxidative stress in neuroblastoma. | Neurochemical research 20100301 |
| A vitamin/nutriceutical formulation improves memory and cognitive performance in community-dwelling adults without dementia. | The journal of nutrition, health & aging 20100301 |
| [Effect of acetyl-L-carnitine on the insulin resistance of L6 cells induced by tumor necrosis factor-alpha]. | Wei sheng yan jiu = Journal of hygiene research 20100301 |
| The neuropathy-protective agent acetyl-L-carnitine activates protein kinase C-gamma and MAPKs in a rat model of neuropathic pain. | Neuroscience 20100217 |
| Carnitine for fatigue in multiple sclerosis. | The Cochrane database of systematic reviews 20100217 |
| Involvement of OCTN2 in the transport of acetyl-L-carnitine across the inner blood-retinal barrier. | Investigative ophthalmology & visual science 20100101 |
| Acylcarnitines: role in brain. | Progress in lipid research 20100101 |
| Redox homeostasis and cellular stress response in aging and neurodegeneration. | Methods in molecular biology (Clifton, N.J.) 20100101 |
| Muscle unloading potentiates the effects of acetyl-L-carnitine on the slow oxidative muscle phenotype. | BioFactors (Oxford, England) 20100101 |
| Acetyl-L-carnitine attenuates okadaic acid induced tau hyperphosphorylation and spatial memory impairment in rats. | Journal of Alzheimer's disease : JAD 20100101 |
| Acetyl-L-carnitine supplementation to old rats partially reverts the age-related mitochondrial decay of soleus muscle by activating peroxisome proliferator-activated receptor gamma coactivator-1alpha-dependent mitochondrial biogenesis. | Rejuvenation research 20100101 |
| Combined R-alpha-lipoic acid and acetyl-L-carnitine exerts efficient preventative effects in a cellular model of Parkinson's disease. | Journal of cellular and molecular medicine 20100101 |
| Optimal micronutrients delay mitochondrial decay and age-associated diseases. | Mechanisms of ageing and development 20100101 |
| Acetyl-L-carnitine for alcohol craving and relapse prevention in anhedonic alcoholics: a randomized, double-blind, placebo-controlled pilot trial. | Alcohol and alcoholism (Oxford, Oxfordshire) 20100101 |
| Plasma metabolomic profiles reflective of glucose homeostasis in non-diabetic and type 2 diabetic obese African-American women. | PloS one 20100101 |
| Tissue-specific short chain fatty acid metabolism and slow metabolic recovery after ischemia from hyperpolarized NMR in vivo. | The Journal of biological chemistry 20091225 |
| Short-term supplementation with acetyl-L-carnitine and lipoic acid alters plasma protein carbonyl levels but does not improve cognition in aged beagles. | Experimental gerontology 20091201 |
| Mitochondria in the elderly: Is acetylcarnitine a rejuvenator? | Advanced drug delivery reviews 20091130 |
| A case of holocarboxylase synthetase deficiency with insufficient response to prenatal biotin therapy. | Brain & development 20091101 |
| Effect of L-acetylcarnitine on body composition in HIV-related lipodystrophy. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20091101 |
| Effect of acetyl-L-carnitine on axonal sprouting following donor nerve injury distal to an end-to-side neurorrhaphy model. | Journal of reconstructive microsurgery 20091101 |
| Ameliorating hypertension and insulin resistance in subjects at increased cardiovascular risk: effects of acetyl-L-carnitine therapy. | Hypertension (Dallas, Tex. : 1979) 20090901 |
| Hypertension and insulin resistance. | Hypertension (Dallas, Tex. : 1979) 20090901 |
| Mitochondrial acetylcarnitine provides acetyl groups for nuclear histone acetylation. | Epigenetics 20090816 |
| The effect of acetyl-L-carnitine and R-alpha-lipoic acid treatment in ApoE4 mouse as a model of human Alzheimer's disease. | Journal of the neurological sciences 20090815 |
| Defective inhibition and inter-regional phase synchronization in pianists with musician's dystonia: an EEG study. | Human brain mapping 20090801 |
| Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090801 |
| Oral acetate supplementation after prolonged moderate intensity exercise enhances early muscle glycogen resynthesis in horses. | Experimental physiology 20090801 |
| Accumulation of overoxidized Peroxiredoxin III in aged rat liver mitochondria. | Biochimica et biophysica acta 20090701 |
| Branched chain amino acids supplemented with L-acetylcarnitine versus BCAA treatment in hepatic coma: a randomized and controlled double blind study. | European journal of gastroenterology & hepatology 20090701 |
| Acetyl-L-carnitine ameliorates caerulein-induced acute pancreatitis in rats. | Basic & clinical pharmacology & toxicology 20090701 |
| 1H NMR to investigate metabolism and energy supply in rhesus macaque sperm. | Reproductive toxicology (Elmsford, N.Y.) 20090701 |
| Acetyl-l-carnitine (ALCAR) prevents hypobaric hypoxia-induced spatial memory impairment through extracellular related kinase-mediated nuclear factor erythroid 2-related factor 2 phosphorylation. | Neuroscience 20090630 |
| Sodium azide induced neuronal damage in vitro: evidence for non-apoptotic cell death. | Neurochemical research 20090501 |
| The effect of acetyl-L-carnitine on lenticular calpain activity in prevention of selenite-induced cataractogenesis. | Experimental eye research 20090501 |
| Systematic analysis of adaptations in aerobic capacity and submaximal energy metabolism provides a unique insight into determinants of human aerobic performance. | Journal of applied physiology (Bethesda, Md. : 1985) 20090501 |
| Mitochondrial decay in the brains of old rats: ameliorating effect of alpha-lipoic acid and acetyl-L-carnitine. | Neurochemical research 20090401 |
| Cytoprotective effect of acetyl-L-carnitine evidenced by analysis of gene expression in the rat brain. | Molecular neurobiology 20090401 |
| Cerebral metabolic effects of acetyl-l-carnitine in rats during aging. | Brain research 20090309 |
| The effect of 3-hydroxybutyrate methyl ester on learning and memory in mice. | Biomaterials 20090301 |
| Effect of acetyl-l-carnitine on ovarian cancer cells' proliferation, nerve growth factor receptor (Trk-A and p75) expression, and the cytotoxic potential of paclitaxel and carboplatin. | Gynecologic oncology 20090301 |
| Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats. | Journal of cellular and molecular medicine 20090201 |
| Comparison of pharmacokinetics of L-carnitine, acetyl-L-carnitine and propionyl-L-carnitine after single oral administration of L-carnitine in healthy volunteers. | Clinical and investigative medicine. Medecine clinique et experimentale 20090201 |
| Acetyl-l-carnitine and nucleoside reverse transcriptase inhibitor-associated neuropathy in HIV infection. | HIV medicine 20090201 |
| Acetyl-L-carnitine provides effective in vivo neuroprotection over 3,4-methylenedioximethamphetamine-induced mitochondrial neurotoxicity in the adolescent rat brain. | Neuroscience 20090123 |
| Acetyl-l-carnitine inhibits TNF-alpha-induced insulin resistance via AMPK pathway in rat skeletal muscle cells. | FEBS letters 20090122 |
| Neuroprotective effects of acetyl-L-carnitine on neuropathic pain and apoptosis: a role for the nicotinic receptor. | Journal of neuroscience research 20090101 |
| Medical management of Peyronie's disease. | Journal of andrology 20090101 |
| Acetyl-L-carnitine in the management of pain during methadone withdrawal syndrome. | Clinical neuropharmacology 20090101 |
| Dietary supplementation with a combination of alpha-lipoic acid, acetyl-L-carnitine, glycerophosphocoline, docosahexaenoic acid, and phosphatidylserine reduces oxidative damage to murine brain and improves cognitive performance. | Nutrition research (New York, N.Y.) 20090101 |
| Effects of acetylo-L-carnitine in end-to-side neurorrhaphy: a pilot study. | Microsurgery 20090101 |
| Vitagenes, cellular stress response, and acetylcarnitine: relevance to hormesis. | BioFactors (Oxford, England) 20090101 |
| Evaluation of lenticular antioxidant and redox system components in the lenses of acetyl-L-carnitine treatment in BSO-induced glutathione deprivation. | Molecular vision 20090101 |
| Systematic review of pharmacological treatments in fragile X syndrome. | BMC neurology 20090101 |
| Evaluation of the effect of acetyl L-carnitine on experimental cisplatin nephrotoxicity. | Chemotherapy 20090101 |
| Treatments for fragile X syndrome: a closer look at the data. | Developmental disabilities research reviews 20090101 |
| Up-regulation of kinesin light-chain 1 gene expression by acetyl-L-carnitine: therapeutic possibility in Alzheimer's disease. | Neurochemistry international 20081201 |
| Modulatory effect of acetyl-L-carnitine on amyloid precursor protein metabolism in hippocampal neurons. | European journal of pharmacology 20081112 |
| Acetyl-L-carnitine treatment in minimal hepatic encephalopathy. | Digestive diseases and sciences 20081101 |
| Determination of the reference range of endogenous plasma carnitines in healthy adults. | Annals of clinical biochemistry 20081101 |
| Role of acetyl-L-carnitine in the treatment of diabetic peripheral neuropathy. | The Annals of pharmacotherapy 20081101 |
| Acetyl-L-carnitine suppresses apoptosis of thioredoxin 2-deficient DT40 cells. | Archives of biochemistry and biophysics 20081015 |
| In the rat brain acetyl-L-carnitine treatment modulates the expression of genes involved in neuronal ceroid lipofuscinosis. | Molecular neurobiology 20081001 |
| Hypoxia-induced deactivation of NGF-mediated ERK1/2 signaling in hippocampal cells: neuroprotection by acetyl-L-carnitine. | Journal of neuroscience research 20080901 |
| A DIGE approach for the assessment of rat soleus muscle changes during unloading: effect of acetyl-L-carnitine supplementation. | Proteomics 20080901 |
| Acetyl-L-Carnitine selectively prevents post-ischemic LTP via a possible action on mitochondrial energy metabolism. | Neuropharmacology 20080801 |
| Change in the membranous lipid composition accelerates lipid peroxidation in young rat hearts subjected to 2 weeks of hypoxia followed by hyperoxia. | Circulation journal : official journal of the Japanese Circulation Society 20080801 |
| Preventive effect of acetyl-L-carnitine on the thermal hypoalgesia in streptozotocin-induced diabetic mice. | European journal of pharmacology 20080707 |
| Protective effects of R-alpha-lipoic acid and acetyl-L-carnitine in MIN6 and isolated rat islet cells chronically exposed to oleic acid. | Journal of cellular biochemistry 20080701 |
| Chemotherapy-induced peripheral neuropathy: prevention and treatment strategies. | European journal of cancer (Oxford, England : 1990) 20080701 |
| Acetyl-L-carnitine and alpha-lipoic acid: possible neurotherapeutic agents for mood disorders? | Expert opinion on investigational drugs 20080601 |
| [Physiological functions of carnitine and carnitine transporters in the central nervous system]. | Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20080601 |
| Chemotherapy-evoked neuropathic pain: Abnormal spontaneous discharge in A-fiber and C-fiber primary afferent neurons and its suppression by acetyl-L-carnitine. | Pain 20080401 |
| A double-blind, parallel, multicenter comparison of L-acetylcarnitine with placebo on the attention deficit hyperactivity disorder in fragile X syndrome boys. | American journal of medical genetics. Part A 20080401 |
| Muscular metabolism in aged rats under exhaustive exercise: effect of a modified alkaline supplementation. | Rejuvenation research 20080401 |
| Prevention of paclitaxel-evoked painful peripheral neuropathy by acetyl-L-carnitine: effects on axonal mitochondria, sensory nerve fiber terminal arbors, and cutaneous Langerhans cells. | Experimental neurology 20080301 |
| [Clinical efficacy of combined L-carnitine and acetyl-L-carnitine on idiopathic asthenospermia]. | Zhonghua nan ke xue = National journal of andrology 20080201 |
| Acetyl L-carnitine (ALC) treatment in elderly patients with fatigue. | Archives of gerontology and geriatrics 20080101 |
| R-alpha-lipoic acid and acetyl-L-carnitine complementarily promote mitochondrial biogenesis in murine 3T3-L1 adipocytes. | Diabetologia 20080101 |
| Lipoic acid and acetyl-carnitine reverse iron-induced oxidative stress in human fibroblasts. | Redox report : communications in free radical research 20080101 |
| Thioctic acid and acetyl-L-carnitine in the treatment of sciatic pain caused by a herniated disc: a randomized, double-blind, comparative study. | Clinical drug investigation 20080101 |
| Multiple dosing strategies with acetyl L-carnitine (ALCAR) fail to alter age-related hearing loss in the Fischer 344/NHsd rat. | Journal of negative results in biomedicine 20080101 |
| L-carnitine and its derivatives: exciting experimental and clinical data are accumulating in the treatment of ocular disorders. | Drugs in R&D 20080101 |
| The aging eye and the role of L-carnitine and its derivatives. | Drugs in R&D 20080101 |
| [Metabolic therapy for early treatment of age-related macular degeneration]. | Orvosi hetilap 20071202 |
| Metabolomics identifies perturbations in human disorders of propionate metabolism. | Clinical chemistry 20071201 |
| Natural antioxidants in Alzheimer's disease. | Expert opinion on investigational drugs 20071201 |
| Putting evidence into practice: evidence-based interventions for chemotherapy-induced peripheral neuropathy. | Clinical journal of oncology nursing 20071201 |
| Valproate and acetyl-L-carnitine prevent methamphetamine-induced behavioral sensitization in mice. | Annals of the New York Academy of Sciences 20071201 |
| Acetyl-L-carnitine (ALC) in attention-deficit/hyperactivity disorder: a multi-site, placebo-controlled pilot trial. | Journal of child and adolescent psychopharmacology 20071201 |
| Acetyl-L-carnitine and alpha-lipoic acid supplementation of aged beagle dogs improves learning in two landmark discrimination tests. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20071101 |
| Protective effect of intravenous levocarnitine on subsequent-month hospitalization among prevalent hemodialysis patients, 1998 to 2003. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20071101 |
| Transport of carnitine and acetylcarnitine by carnitine/organic cation transporter (OCTN) 2 and OCTN3 into epididymal spermatozoa. | Reproduction (Cambridge, England) 20071101 |
| Acetyl-L-carnitine prevents selenite-induced cataractogenesis in an experimental animal model. | Current eye research 20071101 |
| Elevated free fatty acids attenuate the insulin-induced suppression of PDK4 gene expression in human skeletal muscle: potential role of intramuscular long-chain acyl-coenzyme A. | The Journal of clinical endocrinology and metabolism 20071001 |
| Investigations of the effects of gender, diurnal variation, and age in human urinary metabolomic profiles. | Analytical chemistry 20070915 |
| Acetyl-L-carnitine ameliorates hypobaric hypoxic impairment and spatial memory deficits in rats. | European journal of pharmacology 20070910 |
| Protective effect of acetyl-L-carnitine on the apoptotic pathway of peripheral neuropathy. | The European journal of neuroscience 20070801 |
| Urinary excretion of L-carnitine and its short-chain acetyl-L-carnitine in patients undergoing carboplatin treatment. | Cancer chemotherapy and pharmacology 20070601 |
| New insights concerning the role of carnitine in the regulation of fuel metabolism in skeletal muscle. | The Journal of physiology 20070601 |
| [Molecular/neural mechanisms of fatigue]. | Nihon rinsho. Japanese journal of clinical medicine 20070601 |
| Is the human masticatory system devoid of recurrent inhibition? | Experimental brain research 20070501 |
| A double-blind, parallel-group, placebo-controlled, multicentre study of acetyl L-carnitine in the symptomatic treatment of antiretroviral toxic neuropathy in patients with HIV-1 infection. | HIV medicine 20070501 |
| Pharmacological rescue of noise induced hearing loss using N-acetylcysteine and acetyl-L-carnitine. | Hearing research 20070401 |
| Recurrence quantification analysis of surface EMG detects changes in motor unit synchronization induced by recurrent inhibition. | Experimental brain research 20070401 |
| Effect of combined treatment with alpha-Lipoic acid and acetyl-L-carnitine on vascular function and blood pressure in patients with coronary artery disease. | Journal of clinical hypertension (Greenwich, Conn.) 20070401 |
| More light please. | Journal of clinical hypertension (Greenwich, Conn.) 20070401 |
| Neuroprotective effects of acetyl-L-carnithine in experimental chronic compression neuropathy. A prospective, randomized and placebo-control trials. | Turkish neurosurgery 20070401 |
| Involvement of PI3K/PKG/ERK1/2 signaling pathways in cortical neurons to trigger protection by cotreatment of acetyl-L-carnitine and alpha-lipoic acid against HNE-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease. | Free radical biology & medicine 20070201 |
| [Molecular/neural mechanisms of fatigue and the way to overcome fatigue]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20070201 |
| Delayed acetyl-L-carnitine administration and its effect on sensory neuronal rescue after peripheral nerve injury. | Journal of plastic, reconstructive & aesthetic surgery : JPRAS 20070101 |
| Effect of L-carnitine and/or L-acetyl-carnitine in nutrition treatment for male infertility: a systematic review. | Asia Pacific journal of clinical nutrition 20070101 |
| Double-blind, multicenter trial comparing acetyl l-carnitine with placebo in the treatment of fibromyalgia patients. | Clinical and experimental rheumatology 20070101 |
| Overview on pathophysiology and newer approaches to treatment of peripheral neuropathies. | CNS drugs 20070101 |
| Acetyl-L-carnitine in diabetic polyneuropathy: experimental and clinical data. | CNS drugs 20070101 |
| Acetyl-L-carnitine in HIV-associated antiretroviral toxic neuropathy. | CNS drugs 20070101 |
| Acetyl-L-carnitine in neuropathic pain: experimental data. | CNS drugs 20070101 |
| Acetyl-L-carnitine for the treatment of chemotherapy-induced peripheral neuropathy: a short review. | CNS drugs 20070101 |
| Effects of dietary supplementation with N-acetyl cysteine, acetyl-L-carnitine and S-adenosyl methionine on cognitive performance and aggression in normal mice and mice expressing human ApoE4. | Neuromolecular medicine 20070101 |
| Protective effect of acetyl-L-carnitine against oxidative stress induced by antiretroviral drugs. | FEBS letters 20061211 |
| Prevention of selenite-induced cataractogenesis by acetyl-L-carnitine: an experimental study. | Experimental eye research 20061201 |
| Effects of L-acetylcarnitine on cirrhotic patients with hepatic coma: randomized double-blind, placebo-controlled trial. | Digestive diseases and sciences 20061201 |
| Acetyl-L-carnitine affects nonassociative learning processes in the leech Hirudo medicinalis. | Neuroscience 20061103 |
| The association of acetyl-l-carnitine and nicotinamide remits the experimental diabetes in mice by multiple low-dose streptozotocin. | Pancreas 20061101 |
| Muscle metabolites: functional MR spectroscopy during exercise imposed by tetanic electrical nerve stimulation. | Radiology 20061001 |
| Susceptibility of human metabolic phenotypes to dietary modulation. | Journal of proteome research 20061001 |
| Systemic lupus erythematosus after mesotherapy with acetyl-L-carnitine. | Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20061001 |
| Protective role of carnitine ester against radiation-induced oxidative stress in rats. | Pharmacological research 20060901 |
| Compensatory responses to pyruvate carboxylase suppression in islet beta-cells. Preservation of glucose-stimulated insulin secretion. | The Journal of biological chemistry 20060804 |
| Acetyl-L-carnitine-induced up-regulation of heat shock proteins protects cortical neurons against amyloid-beta peptide 1-42-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease. | Journal of neuroscience research 20060801 |
| Involvement of recognition and interaction of carnitine transporter in the decrease of L-carnitine concentration induced by pivalic acid and valproic acid. | Pharmaceutical research 20060801 |
| Cloning and functional characterization of a novel up-regulator, cartregulin, of carnitine transporter, OCTN2. | Archives of biochemistry and biophysics 20060801 |
| Carnitine esters prevent oxidative stress damage and energy depletion following transient forebrain ischaemia in the rat hippocampus. | Clinical and experimental pharmacology & physiology 20060801 |
| SANDO: two novel mutations in POLG1 gene. | Neuromuscular disorders : NMD 20060801 |
| Motor unit synchronous firing as revealed by determinism of surface myoelectric signal. | Journal of neuroscience methods 20060715 |
| Monitoring of ketogenic diet for carnitine metabolites by subcutaneous microdialysis. | Pediatric research 20060701 |
| Reversal of mitochondrial defects before ischemia protects the aged heart. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060701 |
| Acetyl-L-carnitine protects striatal neurons against in vitro ischemia: the role of endogenous acetylcholine. | Neuropharmacology 20060601 |
| Acetyl-L-carnitine up-regulates expression of voltage-dependent anion channel in the rat brain. | Neurochemistry international 20060601 |
| Levocarnitine administration in multiple sclerosis patients with immunosuppressive therapy-induced fatigue. | Multiple sclerosis (Houndmills, Basingstoke, England) 20060601 |
| A double-blind, randomised, controlled clinical trial of acetyl-L-carnitine vs. amisulpride in the treatment of dysthymia. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20060501 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Acetyl-L-carnitine prevents and reduces paclitaxel-induced painful peripheral neuropathy. | Neuroscience letters 20060424 |
| Male idiopathic oligoasthenoteratozoospermia. | Asian journal of andrology 20060301 |
| Acetyl-l-carnitine in the treatment of painful antiretroviral toxic neuropathy in human immunodeficiency virus patients: an open label study. | Journal of the peripheral nervous system : JPNS 20060301 |
| Effects of terguride, ropinirole, and acetyl-L-carnitine on methamphetamine withdrawal in the rat. | Pharmacology, biochemistry, and behavior 20060301 |
| Acetylcarnitine and cellular stress response: roles in nutritional redox homeostasis and regulation of longevity genes. | The Journal of nutritional biochemistry 20060201 |
| Behavioral and electrophysiological changes induced by acetyl-L-carnitine in aged freely-moving rats. | Archives italiennes de biologie 20060201 |
| Morphoquantitative aspects of NADH-diaphorase myenteric neurons in the ileum of diabetic rats treated with acetyl-L-carnitine. | Anatomia, histologia, embryologia 20060201 |
| Accumulation of acetyl groups following cycling: a 1H-MR spectroscopy study. | International journal of sports medicine 20060201 |
| Debate forum: levocarnitine therapy is rational and justified in selected dialysis patients. | Blood purification 20060101 |
| Effects of a single, short intravenous dose of acetyl-L-carnitine on pattern-reversal visual-evoked potentials in cirrhotic patients with hepatic encephalopathy. | Clinical and experimental pharmacology & physiology 20060101 |
| The effect of acetyl-L-carnitine administration on persons with Down syndrome. | Research in developmental disabilities 20060101 |
| Proteomics analyses of specific protein oxidation and protein expression in aged rat brain and its modulation by L-acetylcarnitine: insights into the mechanisms of action of this proposed therapeutic agent for CNS disorders associated with oxidative stress. | Antioxidants & redox signaling 20060101 |
| Redox modulation of heat shock protein expression by acetylcarnitine in aging brain: relationship to antioxidant status and mitochondrial function. | Antioxidants & redox signaling 20060101 |
| Transcriptional regulation of metabotropic glutamate receptor 2/3 expression by the NF-kappaB pathway in primary dorsal root ganglia neurons: a possible mechanism for the analgesic effect of L-acetylcarnitine. | Molecular pain 20060101 |
| Acetyl-L-carnitine feeding to unloaded rats triggers in soleus muscle the coordinated expression of genes involved in mitochondrial biogenesis. | Biochimica et biophysica acta 20060101 |
| Carnitine/organic cation transporter OCTN2-mediated transport of carnitine in primary-cultured epididymal epithelial cells. | Reproduction (Cambridge, England) 20051201 |
| Folate, vitamin E, and acetyl-L-carnitine provide synergistic protection against oxidative stress resulting from exposure of human neuroblastoma cells to amyloid-beta. | Brain research 20051109 |
| Acetyl-L-carnitine plus propionyl-L-carnitine improve efficacy of sildenafil in treatment of erectile dysfunction after bilateral nerve-sparing radical retropubic prostatectomy. | Urology 20051101 |
| The European Association of Addiction Therapy - Inaugural Conference. | IDrugs : the investigational drugs journal 20051001 |
| [A controlled randomized trial of the use of combined L-carnitine and acetyl-L-carnitine treatment in men with oligoasthenozoospermia]. | Zhonghua nan ke xue = National journal of andrology 20051001 |
| Placebo-controlled double-blind randomized trial on the use of L-carnitine, L-acetylcarnitine, or combined L-carnitine and L-acetylcarnitine in men with idiopathic asthenozoospermia. | Fertility and sterility 20050901 |
| Enantiomeric purity determination of acetyl-L-carnitine by NMR with chiral lanthanide shift reagents. | Journal of pharmaceutical and biomedical analysis 20050810 |
| Symptomatic and neurophysiological responses of paclitaxel- or cisplatin-induced neuropathy to oral acetyl-L-carnitine. | European journal of cancer (Oxford, England : 1990) 20050801 |
| Mechanisms of ischemic neuroprotection by acetyl-L-carnitine. | Annals of the New York Academy of Sciences 20050801 |
| Probing peroxisomal beta-oxidation and the labelling of acetyl-CoA proxies with [1-(13C)]octanoate and [3-(13C)]octanoate in the perfused rat liver. | The Biochemical journal 20050715 |
| Arabidopsis peroxisomal citrate synthase is required for fatty acid respiration and seed germination. | The Plant cell 20050701 |
| Morphometric and quantitative evaluation of the NADH-diaphorase positive myenteric neurons of the jejunum of streptozotocin-diabetic rats supplemented with acetyl-L-carnitine. | Anatomia, histologia, embryologia 20050601 |
| Reduction of apoptosis through the mitochondrial pathway by the administration of acetyl-L-carnitine to mouse fibroblasts in culture. | Experimental cell research 20050515 |
| Differential carnitine/acylcarnitine translocase expression defines distinct metabolic signatures in skeletal muscle cells. | Journal of cellular physiology 20050501 |
| Differential epigenetic modifications in the FMR1 gene of the fragile X syndrome after reactivating pharmacological treatments. | European journal of human genetics : EJHG 20050501 |
| Delayed therapy of experimental global cerebral ischemia with acetyl-L-carnitine in dogs. | Neuroscience letters 20050418 |
| Morphoquantitative aspects of nitrergic myoenteric neurons from the stomach of diabetic rats supplemented with acetyl-L-carnitine. | Anatomia, histologia, embryologia 20050401 |
| Peroxisomal and mitochondrial oxidation of fatty acids in the heart, assessed from the 13C labeling of malonyl-CoA and the acetyl moiety of citrate. | The Journal of biological chemistry 20050311 |
| Effect of intraperitoneal acetyl-L-carnitine (ALCAR) on anxiety-like behaviours in rats. | The international journal of neuropsychopharmacology 20050301 |
| Strategy for the isolation, derivatization, chromatographic separation, and detection of carnitine and acylcarnitines. | Analytical chemistry 20050301 |
| Prevention of impulse noise-induced hearing loss with antioxidants. | Acta oto-laryngologica 20050301 |
| Acetylcarnitine induces heme oxygenase in rat astrocytes and protects against oxidative stress: involvement of the transcription factor Nrf2. | Journal of neuroscience research 20050215 |
| Acetyl-CoA provision and the acetyl group deficit at the onset of contraction in ischemic canine skeletal muscle. | American journal of physiology. Endocrinology and metabolism 20050201 |
| Malonyl-CoA and carnitine in regulation of fat oxidation in human skeletal muscle during exercise. | American journal of physiology. Endocrinology and metabolism 20050101 |
| Nerve growth factor and acetyl-L-carnitine evoked shifts in acetyl-CoA and cholinergic SN56 cell vulnerability to neurotoxic inputs. | Journal of neuroscience research 20050101 |
| Acetyl-L-carnitine improves pain, nerve regeneration, and vibratory perception in patients with chronic diabetic neuropathy: an analysis of two randomized placebo-controlled trials. | Diabetes care 20050101 |
| Correlation between seminal carnitine and functional spermatozoal characteristics in men with semen dysfunction of various origins. | Drugs in R&D 20050101 |
| Free and total carnitine concentrations in pig plasma after oral ingestion of various L-carnitine compounds. | International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20050101 |
| Chemotherapy-induced allodinia: neuroprotective effect of acetyl-L-carnitine. | In vivo (Athens, Greece) 20050101 |
| Improvement of visual functions and fundus alterations in early age-related macular degeneration treated with a combination of acetyl-L-carnitine, n-3 fatty acids, and coenzyme Q10. | Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20050101 |
| A pilot study on the effect of acetyl-L-carnitine in paclitaxel- and cisplatin-induced peripheral neuropathy. | Tumori 20050101 |
| Evaluation of carnitine, acetylcarnitine and isovalerylcarnitine on immune function and apoptosis. | Drugs under experimental and clinical research 20050101 |
| Acetyl-L-Carnitine prevents and reverts experimental chronic neurotoxicity induced by oxaliplatin, without altering its antitumor properties. | Anticancer research 20050101 |
| HIV-associated antiretroviral toxic neuropathy (ATN): a review of recent advances in pathophysiology and treatment. | Antiviral therapy 20050101 |
| Effects of acetyl-L-carnitine on cardiac dysautonomia in Rett syndrome: prevention of sudden death? | Pediatric cardiology 20050101 |
| A review of antioxidants and Alzheimer's disease. | Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20050101 |
| Long-term effect of acetyl-L-carnitine for antiretroviral toxic neuropathy. | HIV clinical trials 20050101 |
| [Vitamine-like substances L-carnitine and acetyl-L-carnitine: from biochemical studies to medicine]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20050101 |
| Identification of differentially expressed genes induced in the rat brain by acetyl-L-carnitine as evidenced by suppression subtractive hybridisation. | Brain research. Molecular brain research 20041206 |
| Effects of 7 wk of endurance training on human skeletal muscle metabolism during submaximal exercise. | Journal of applied physiology (Bethesda, Md. : 1985) 20041201 |
| Acetyl-L-carnitine reduces impulsive behaviour in adolescent rats. | Psychopharmacology 20041101 |
| Kinetics, pharmacokinetics, and regulation of L-carnitine and acetyl-L-carnitine metabolism. | Annals of the New York Academy of Sciences 20041101 |
| Delaying the mitochondrial decay of aging with acetylcarnitine. | Annals of the New York Academy of Sciences 20041101 |
| Comparison of the effects of L-carnitine and acetyl-L-carnitine on carnitine levels, ambulatory activity, and oxidative stress biomarkers in the brain of old rats. | Annals of the New York Academy of Sciences 20041101 |
| Acetyl-L-carnitine for the treatment of HIV lipoatrophy. | Annals of the New York Academy of Sciences 20041101 |
| Impact of hemodialysis on endogenous plasma and muscle carnitine levels in patients with end-stage renal disease. | Kidney international 20041001 |
| Role of mitochondrial dysfunction in neurotoxicity of MPP+: partial protection of PC12 cells by acetyl-L-carnitine. | Annals of the New York Academy of Sciences 20041001 |
| Natural antioxidants and neurodegenerative diseases. | Frontiers in bioscience : a journal and virtual library 20040901 |
| Acetyl-L-carnitine requires phospholipase C-IP3 pathway activation to induce antinociception. | Neuropharmacology 20040801 |
| Effect of L-carnitine administration on the seminal characteristics of oligoasthenospermic stallions. | Theriogenology 20040801 |
| Acetyl-L-carnitine prevents total body hydroxyl free radical and uric acid production induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the rat. | Life sciences 20040723 |
| Acetyl-l-carnitine: a pathogenesis based treatment for HIV-associated antiretroviral toxic neuropathy. | AIDS (London, England) 20040723 |
| Propofol infusion in children: when does an anesthetic tool become an intensive care liability? | Paediatric anaesthesia 20040601 |
| A placebo-controlled double-blind randomized trial of the use of combined l-carnitine and l-acetyl-carnitine treatment in men with asthenozoospermia. | Fertility and sterility 20040601 |
| Delaying the mitochondrial decay of aging. | Annals of the New York Academy of Sciences 20040601 |
| Acetyl-L-carnitine dietary supplementation to old rats increases mitochondrial transcription factor A content in rat hindlimb skeletal muscles. | Annals of the New York Academy of Sciences 20040601 |
| HPLC determination and pharmacokinetics of endogenous acetyl-L-carnitine (ALC) in human volunteers orally administered a single dose of ALC. | Archives of pharmacal research 20040601 |
| Response to therapy in carnitine/acylcarnitine translocase (CACT) deficiency due to a novel missense mutation. | American journal of medical genetics. Part A 20040415 |
| Acetyl-L-carnitine supplementation restores decreased tissue carnitine levels and impaired lipid metabolism in aged rats. | Journal of lipid research 20040401 |
| Effects of carnitines on rat sertoli cell protein metabolism. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20040401 |
| Carnitines and male infertility. | Reproductive biomedicine online 20040401 |
| Comparison of the effects of acetyl L-carnitine and amantadine for the treatment of fatigue in multiple sclerosis: results of a pilot, randomised, double-blind, crossover trial. | Journal of the neurological sciences 20040315 |
| Repeated acetyl-l-carnitine administration increases phospho-Thr34 DARPP-32 levels and antagonizes cocaine-induced increase in Cdk5 and phospho-Thr75 DARPP-32 levels in rat striatum. | The European journal of neuroscience 20040301 |
| Complications & side effects. Supplements and CD4+ counts: study finds surprising results. | TreatmentUpdate 20040301 |
| Glutamate-induced over-expression of GAD is down-regulated by acetyl-L-carnitine in rat islet cells. | Endocrine research 20040201 |
| Exploratory open label, randomized study of acetyl- and propionylcarnitine in chronic fatigue syndrome. | Psychosomatic medicine 20040101 |
| Brain cholinesterases: III. Future perspectives of AD research and clinical practice. | Medical hypotheses 20040101 |
| Cinnoxicam and L-carnitine/acetyl-L-carnitine treatment for idiopathic and varicocele-associated oligoasthenospermia. | Journal of andrology 20040101 |
| Acetyl-L-carnitine induces a sustained potentiation of the afterhyperpolarization. | Neuroscience 20040101 |
| Metabotropic receptors as targets for drugs of potential use in the treatment of neuropathic pain. | Journal of endocrinological investigation 20040101 |
| Primary sensory neuronal rescue with systemic acetyl-L-carnitine following peripheral axotomy. A dose-response analysis. | British journal of plastic surgery 20031201 |
| Effects of L-carnitine and its derivatives on postischemic cardiac function, ventricular fibrillation and necrotic and apoptotic cardiomyocyte death in isolated rat hearts. | Molecular and cellular biochemistry 20031201 |
| Effect of acetyl-L-carnitine on VIP-ergic neurons in the jejunum submucous plexus of diabetic rats. | Arquivos de neuro-psiquiatria 20031201 |
| Paclitaxel and Cisplatin-induced neurotoxicity: a protective role of acetyl-L-carnitine. | Clinical cancer research : an official journal of the American Association for Cancer Research 20031115 |
| Acetyl-L-carnitine permeability across the blood-brain barrier and involvement of carnitine transporter OCTN2. | Biopharmaceutics & drug disposition 20031101 |
| Protective role of carnitine esters against alcohol-induced gastric lesions in rats. | Pharmacological research 20030901 |
| Disruption of thiol homeostasis and nitrosative stress in the cerebrospinal fluid of patients with active multiple sclerosis: evidence for a protective role of acetylcarnitine. | Neurochemical research 20030901 |
| Effect of PPF and ALCAR on the induction of NGF- and p75-mRNA and on APP processing in Tg2576 brain. | Neurochemistry international 20030801 |
| Biosensors for the determination of ortho-acetyl-L-carnitine. Their utilization as detectors in a sequential injection analysis system. | Preparative biochemistry & biotechnology 20030801 |
| Acetyl-L-carnitine cytoprotection against 1-methyl-4-phenylpyridinium toxicity in neuroblastoma cells. | Biochemical pharmacology 20030715 |
| Role of acetyl-L-carnitine in the brain: revealed by Bioradiography. | Biochemical and biophysical research communications 20030711 |
| Deficiency in short-chain fatty acid beta-oxidation affects theta oscillations during sleep. | Nature genetics 20030701 |
| Modulation of methylation in the FMR1 promoter region after long term treatment with L-carnitine and acetyl-L-carnitine. | Journal of medical genetics 20030601 |
| [Neural and molecular mechanisms of fatigue and recovery from fatigue]. | Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20030601 |
| Effects of acetyl-L-carnitine and myo-inositol on high-energy phosphate and membrane phospholipid metabolism in zebra fish: a 31P-NMR-spectroscopy study. | Neurochemical research 20030501 |
| Pharmacologically induced enhancement of recurrent inhibition in humans: effects on motoneurone discharge patterns. | The Journal of physiology 20030415 |
| Effects of long-term acetyl-L-carnitine administration in rats--II: Protection against the disrupting effect of stress on the acquisition of appetitive behavior. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030401 |
| The lowdown on Ginkgo biloba. | Scientific American 20030401 |
| Meta-analysis of double blind randomized controlled clinical trials of acetyl-L-carnitine versus placebo in the treatment of mild cognitive impairment and mild Alzheimer's disease. | International clinical psychopharmacology 20030301 |
| Bioenergetic approaches for neuroprotection in Parkinson's disease. | Annals of neurology 20030101 |
| Acetyl-L-carnitine for dementia. | The Cochrane database of systematic reviews 20030101 |
| Effects of acetyl-L-carnitine in Alzheimer's disease patients unresponsive to acetylcholinesterase inhibitors. | Current medical research and opinion 20030101 |
| Mitotropic compounds for the treatment of age-related macular degeneration. The metabolic approach and a pilot study. | Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20030101 |
| 'Brain-specific' nutrients: a memory cure? | Nutrition (Burbank, Los Angeles County, Calif.) 20030101 |
| Effects of chronic acetyl-L-carnitine treatment on brain lipid hydroperoxide level and passive avoidance learning in senescence-accelerated mice. | Neuroscience letters 20021216 |
| Pharmacological enhancement of peripheral nerve regeneration in the rat by systemic acetyl-L-carnitine treatment. | Neuroscience letters 20021216 |
| Reversal of biochemical and behavioral parameters of brain aging by melatonin and acetyl L-carnitine. | Brain research 20021213 |
| Effect of active warm-up on metabolism prior to and during intense dynamic exercise. | Medicine and science in sports and exercise 20021201 |
| Acetyl-l-carnitine induces muscarinic antinocieption in mice and rats. | Neuropharmacology 20021201 |
| The temporal relationship between glycogen phosphorylase and activation of the pyruvate dehydrogenase complex during adrenaline infusion in resting canine skeletal muscle. | The Journal of physiology 20021115 |
| Carbohydrate ingestion reduces skeletal muscle acetylcarnitine availability but has no effect on substrate phosphorylation at the onset of exercise in man. | The Journal of physiology 20021101 |
| Brain regions involved in fatigue sensation: reduced acetylcarnitine uptake into the brain. | NeuroImage 20021101 |
| Effects of acetyl-L-carnitine on regional cerebral glucose metabolism in awake rats. | Brain research 20021004 |
| Acetyl-L-carnitine shows neuroprotective and neurotrophic activity in primary culture of rat embryo motoneurons. | Neuroscience letters 20020906 |
| Effects of long-term acetyl-L-carnitine administration in rats: I. increased dopamine output in mesocorticolimbic areas and protection toward acute stress exposure. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20020901 |
| Candidate's thesis: enhancing intrinsic cochlear stress defenses to reduce noise-induced hearing loss. | The Laryngoscope 20020901 |
| Dissection of metabolic, vascular, and nerve conduction interrelationships in experimental diabetic neuropathy by cyclooxygenase inhibition and acetyl-L-carnitine administration. | Diabetes 20020801 |
| Analysis of mitochondrial fatty acid oxidation intermediates by tandem mass spectrometry from intact mitochondria prepared from homogenates of cultured fibroblasts, skeletal muscle cells, and fresh muscle. | Pediatric research 20020701 |
| Systemic acetyl-L-carnitine eliminates sensory neuronal loss after peripheral axotomy: a new clinical approach in the management of peripheral nerve trauma. | Experimental brain research 20020701 |
| Bicarbonate-induced alkalosis augments cellular acetyl group availability and isometric force during the rest-to-work transition in canine skeletal muscle. | Experimental physiology 20020701 |
| Potential role of levocarnitine supplementation for the treatment of chemotherapy-induced fatigue in non-anaemic cancer patients. | British journal of cancer 20020617 |
| Intramuscular triacylglycerol, glycogen and acetyl group metabolism during 4 h of moderate exercise in man. | The Journal of physiology 20020615 |
| Autonomic neuropathy in streptozotocin diabetic rats: effect of acetyl-L-carnitine. | Diabetes research and clinical practice 20020601 |
| Acetyl-L-carnitine protects against amyloid-beta neurotoxicity: roles of oxidative buffering and ATP levels. | Neurochemical research 20020601 |
| L-Acetylcarnitine induces analgesia by selectively up-regulating mGlu2 metabotropic glutamate receptors. | Molecular pharmacology 20020501 |
| Delaying brain mitochondrial decay and aging with mitochondrial antioxidants and metabolites. | Annals of the New York Academy of Sciences 20020401 |
| Mitochondrial decay in the aging rat heart: evidence for improvement by dietary supplementation with acetyl-L-carnitine and/or lipoic acid. | Annals of the New York Academy of Sciences 20020401 |
| [Assay of carnitine in plasma and urine of healthy adults]. | Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20020401 |
| Tandem mass spectrometric assay for the determination of carnitine palmitoyltransferase II activity in muscle tissue. | Analytical biochemistry 20020315 |
| 31P-MRS study of acetyl-L-carnitine treatment in geriatric depression: preliminary results. | Bipolar disorders 20020201 |
| Activation of AMP kinase enhances sensitivity of muscle glucose transport to insulin. | American journal of physiology. Endocrinology and metabolism 20020101 |
| Oxygen uptake on-kinetics in dog gastrocnemius in situ following activation of pyruvate dehydrogenase by dichloroacetate. | The Journal of physiology 20020101 |
| Acetyl-L-carnitine (levacecarnine) in the treatment of diabetic neuropathy. A long-term, randomised, double-blind, placebo-controlled study. | Drugs in R&D 20020101 |
| Long-term ethanol administration enhances age-dependent modulation of redox state in brain and peripheral organs of rat: protection by acetyl carnitine. | International journal of tissue reactions 20020101 |
| Long-term ethanol administration enhances age-dependent modulation of redox state in different brain regions in the rat: protection by acetyl carnitine. | International journal of tissue reactions 20020101 |
| Effects of acetate infusion and hyperoxia on muscle substrate phosphorylation after onset of moderate exercise. | American journal of physiology. Endocrinology and metabolism 20011201 |
| Functional relevance of carnitine transporter OCTN2 to brain distribution of L-carnitine and acetyl-L-carnitine across the blood-brain barrier. | Journal of neurochemistry 20011201 |
| Valproic acid triggers acute rhabdomyolysis in a patient with carnitine palmitoyltransferase type II deficiency. | Neuromuscular disorders : NMD 20011101 |
| Effects of treatment with carnitines in infertile patients with prostato-vesiculo-epididymitis. | Human reproduction (Oxford, England) 20011101 |
| Enhancement of learning capacity and cholinergic synaptic function by carnitine in aging rats. | Journal of neuroscience research 20011015 |
| The effects of increasing exercise intensity on muscle fuel utilisation in humans. | The Journal of physiology 20011001 |
| Lethal neonatal presentation of carnitine palmitoyltransferase I deficiency. | Journal of inherited metabolic disease 20011001 |
| [L-acetylcarnitine treatment on fragile X patients hyperactive behaviour]. | Revista de neurologia 20011001 |
| Carnitine protects the molecular chaperone activity of lens alpha-crystallin and decreases the post-translational protein modifications induced by oxidative stress. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010701 |
| Acetyl-L-carnitine vs tamoxifen in the oral therapy of Peyronie's disease: a preliminary report. | BJU international 20010701 |
| The action of acetyl-L-carnitine on the neurotoxicity evoked by amyloid fragments and peroxide on primary rat cortical neurones. | Annals of the New York Academy of Sciences 20010601 |
| A polymeric microfluidic chip for CE/MS determination of small molecules. | Analytical chemistry 20010501 |
| A new technique to elevate night time growth hormone release and a potential growth hormone feedback control loop. | Medical hypotheses 20010501 |
| Chip-based quantitative capillary electrophoresis/mass spectrometry determination of drugs in human plasma. | Analytical chemistry 20010401 |
| Acetyl-L-carnitine enhances Na(+), K(+)-ATPase glutathione-S-transferase and multiple unit activity and reduces lipid peroxidation and lipofuscin concentration in aged rat brain regions. | Neuroscience letters 20010323 |
| Enzymatic determination of acetylcarnitine for diagnostic applications. | Journal of pharmaceutical and biomedical analysis 20010301 |
| Acetyl-L-carnitine treatment stimulates oxygen consumption and biosynthetic function in perfused liver of young and old rats. | Cellular and molecular life sciences : CMLS 20010301 |
| Hepatic mitochondrial proteins in congenitally hyperammonemic spf mice: effect of acetyl-L-carnitine. | Bioscience, biotechnology, and biochemistry 20010301 |
| A 1-year controlled trial of acetyl-L-carnitine in early-onset AD. | Neurology 20010213 |
| Effects of acetyl-L-carnitine on the formation of fatty acid ethyl esters in brain and peripheral organs after short-term ethanol administration in rat. | Neurochemical research 20010201 |
| Acetyl-L-carnitine infusion increases glucose disposal in type 2 diabetic patients. | Metabolism: clinical and experimental 20000601 |
| beta-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter. | The Journal of biological chemistry 20000121 |
| Acetyl-carnitine deficiency in AIDS patients with neurotoxicity on treatment with antiretroviral nucleoside analogues. | AIDS (London, England) 19970201 |
| L-acetylcarnitine treatment of mental decline in the elderly. | Drugs under experimental and clinical research 19940101 |
| [Effect of DL-carnitine and gamma-butyrobetaine hydroxylase inhibitor 3-(2,2,2-trimethylhydrazinium) propionate on isoproterenol-induced changes in the metabolism of the rat myocardium]. | Voprosy meditsinskoi khimii 19880101 |
| Effect of clofibrate treatment on acylcarnitine oxidation in isolated rat liver mitochondria. | Medical biology 19790201 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.