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5053-08-7 | 2-OXAZOLIDINONE-5-SPIRO-4'-[N-(2-PHENYLETHYL)PIPERIDINE] HYDROCHLORIDE
CAS No: 5053-08-7 Catalog No: AG00DEIW MDL No:MFCD00133315
Product Description
Catalog Number:
AG00DEIW
Chemical Name:
2-OXAZOLIDINONE-5-SPIRO-4'-[N-(2-PHENYLETHYL)PIPERIDINE] HYDROCHLORIDE
CAS Number:
5053-08-7
Molecular Formula:
C15H21ClN2O2
Molecular Weight:
296.7924
MDL Number:
MFCD00133315
IUPAC Name:
8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one;hydrochloride
InChI:
InChI=1S/C15H20N2O2.ClH/c18-14-16-12-15(19-14)7-10-17(11-8-15)9-6-13-4-2-1-3-5-13;/h1-5H,6-12H2,(H,16,18);1H
InChI Key:
FIKFLLIUPUVONI-UHFFFAOYSA-N
SMILES:
O=C1NCC2(O1)CCN(CC2)CCc1ccccc1.Cl
EC Number:
225-752-9
UNII:
832NBX878V
NSC Number:
757825
Properties
Complexity:
318
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
296.129g/mol
Formal Charge:
0
Heavy Atom Count:
20
Hydrogen Bond Acceptor Count:
3
Hydrogen Bond Donor Count:
2
Isotope Atom Count:
0
Molecular Weight:
296.795g/mol
Monoisotopic Mass:
296.129g/mol
Rotatable Bond Count:
3
Topological Polar Surface Area:
41.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
| Title | Journal |
|---|---|
| Large-volume injection of sample diluents not miscible with the mobile phase as an alternative approach in sample preparation for bioanalysis: an application for fenspiride bioequivalence. | Bioanalysis 20110901 |
| [The use of eurespal for the treatment of chronic laryngitis]. | Vestnik otorinolaringologii 20110101 |
| [The estimation of clinical efficacy of eurespal in the postoperative period following surgical intervention on paranasal sinuses]. | Vestnik otorinolaringologii 20110101 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| [Experience in using erespal in the treatment of acute respiratory diseases in children in outpatient practice]. | Vestnik otorinolaringologii 20100101 |
| [Pathogenetic correction of postoperative inflammation in modern rhinosurgery]. | Vestnik otorinolaringologii 20100101 |
| [Efficiency of combination therapy for acute otitis media]. | Vestnik otorinolaringologii 20100101 |
| Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. | Nature chemical biology 20091001 |
| [Experience with fenspiride in a rhinosurgeon's practice]. | Vestnik otorinolaringologii 20090101 |
| [Pathogenetic therapy for inflammatory diseases of the middle ear]. | Vestnik otorinolaringologii 20090101 |
| [Clinicofunctional condition and quality of life in patients with chronic obstructive pulmonary disease before and after outpatient treatment with fenspiride]. | Terapevticheskii arkhiv 20080101 |
| [Hearing rehabilitation in patients with acute otitis media treated with fenspiride]. | Vestnik otorinolaringologii 20080101 |
| [The effectiveness of fenspiride in the treatment of patients with chronic obstructive pulmonary disease]. | Klinicheskaia meditsina 20070101 |
| [New pharmaceuticals in treatment of chronic dust bronchitis]. | Klinicheskaia meditsina 20070101 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| [Erespal in combined therapy of acute rhinosinusitis]. | Vestnik otorinolaringologii 20060101 |
| Comparison of fenspiride with beclomethasone as adjunctive anti-inflammatory treatment in patients with chronic obstructive pulmonary disease. | Clinical drug investigation 20060101 |
| [Anti-inflammatory therapy of paranasal sinuses diseases]. | Vestnik otorinolaringologii 20060101 |
| [The effect of fenspiride on the number of exacerbations and the time of first exacerbation in patients with chronic bronchitis]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20050801 |
| [Fenspiride in patients with acute bronchitis]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20050701 |
| [Usefulness of fenspiride in the treatment of acute otitis media in children]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20050601 |
| [Effectiveness and tolerance of fenspiride treatment in chronic sinusitis. Results of the Polish multicenter study]. | Otolaryngologia polska = The Polish otolaryngology 20050101 |
| [Potential of antiinflammatory therapy in patients with chronic obstructive lung disease]. | Klinicheskaia meditsina 20050101 |
| [Acute intoxication with fenspiride]. | Przeglad lekarski 20040101 |
| [Erespal effectiveness in exudative otitis media]. | Vestnik otorinolaringologii 20030101 |
| [Fenspiride-a new alternative on the therapy of obstructive lung disease]. | Pneumologia (Bucharest, Romania) 20030101 |
| [Bronchial inflammation during chronic bronchitis, importance of fenspiride]. | Presse medicale (Paris, France : 1983) 20020901 |
| [ENT inflammation and importance of fenspiride]. | Presse medicale (Paris, France : 1983) 20020901 |
| Detection of fenspiride and identification of in vivo metabolites in horse body fluids by capillary gas chromatography-mass spectrometry: administration, biotransformation and urinary excretion after a single oral dose. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020205 |
| [Experience in treating patients with chronic obstructive bronchitis with fenspirid]. | Terapevticheskii arkhiv 20020101 |
| [Effectiveness of fenspiride in patients with chronic obstructive bronchitis]. | Klinicheskaia meditsina 20010101 |
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