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Home > Nitro Compounds > 504-88-1
CAS No: 504-88-1 Catalog No: AG003JTU MDL No:MFCD00007406
Title | Journal |
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Topiramate mitigates 3-nitropropionic acid-induced striatal neurotoxicity via modulation of AMPA receptors. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20180801 |
Selection of antioxidants against ovarian oxidative stress in mouse model. | Journal of biochemical and molecular toxicology 20171201 |
Ceftriaxone- and N-acetylcysteine-induced brain tolerance to ischemia: Influence on glutamate levels in focal cerebral ischemia. | PloS one 20170101 |
A novel therapeutic application of solid lipid nanoparticles encapsulated thymoquinone (TQ-SLNs) on 3-nitroproponic acid induced Huntington's disease-like symptoms in wistar rats. | Chemico-biological interactions 20160825 |
Failure of Neuroprotection Despite Microglial Suppression by Delayed-Start Myeloperoxidase Inhibition in a Model of Advanced Multiple System Atrophy: Clinical Implications. | Neurotoxicity research 20150101 |
Potential of protease inhibitor in 3-nitropropionic acid induced Huntington's disease like symptoms: mitochondrial dysfunction and neurodegeneration. | Neurotoxicology 20141201 |
Inhibition of Candida albicans isocitrate lyase activity by cadiolides and synoilides from the ascidian Synoicum sp. | Bioorganic & medicinal chemistry letters 20130715 |
Mitochondrial inhibitor models of Huntington's disease and Parkinson's disease induce zinc accumulation and are attenuated by inhibition of zinc neurotoxicity in vitro or in vivo. | Neuro-degenerative diseases 20130101 |
Naringin modulates oxidative stress and inflammation in 3-nitropropionic acid-induced neurodegeneration through the activation of nuclear factor-erythroid 2-related factor-2 signalling pathway. | Neuroscience 20121227 |
The NMDA receptor subunit GluN3A protects against 3-nitroproprionic-induced striatal lesions via inhibition of calpain activation. | Neurobiology of disease 20121201 |
Antibiotic susceptibility profile of Mycobacterium avium subspecies hominissuis is altered in low-iron conditions. | The Journal of antimicrobial chemotherapy 20121201 |
Catechins protect neurons against mitochondrial toxins and HIV proteins via activation of the BDNF pathway. | Journal of neurovirology 20121201 |
Potential neuroprotective effects of hesperidin on 3-nitropropionic acid-induced neurotoxicity in rats. | Neurotoxicology 20121001 |
Synthesis and in vitro antimycobacterial activity of 2-methoxybenzanilides and their thioxo analogues. | European journal of medicinal chemistry 20121001 |
Synthesis and in vitro antimycobacterial and isocitrate lyase inhibition properties of novel 2-methoxy-2'-hydroxybenzanilides, their thioxo analogues and benzoxazoles. | European journal of medicinal chemistry 20121001 |
3-Nitropropionic acid modifies neurotrophin mRNA expression in the mouse striatum: 18S-rRNA is a reliable control gene for studies of the striatum. | Neuroscience bulletin 20121001 |
Expression pattern of ataxia telangiectasia mutated (ATM), p53, Akt, and glycogen synthase kinase-3β in the striatum of rats treated with 3-nitropropionic acid. | Journal of neuroscience research 20120901 |
Activating mitochondrial regulator PGC-1α expression by astrocytic NGF is a therapeutic strategy for Huntington's disease. | Neuropharmacology 20120901 |
Salicylanilide derivatives block Mycobacterium tuberculosis through inhibition of isocitrate lyase and methionine aminopeptidase. | Tuberculosis (Edinburgh, Scotland) 20120901 |
Neuromodulatory propensity of Bacopa monnieri leaf extract against 3-nitropropionic acid-induced oxidative stress: in vitro and in vivo evidences. | Neurotoxicity research 20120801 |
Involvement of the up-regulated FoxO1 expression in follicular granulosa cell apoptosis induced by oxidative stress. | The Journal of biological chemistry 20120727 |
Brief mitochondrial inhibition causes lasting changes in motor behavior and corticostriatal synaptic physiology in the Fischer 344 rat. | Neuroscience 20120726 |
Ionizing radiation induces mitochondrial reactive oxygen species production accompanied by upregulation of mitochondrial electron transport chain function and mitochondrial content under control of the cell cycle checkpoint. | Free radical biology & medicine 20120715 |
Protection by glia-conditioned medium in a cell model of Huntington disease. | PLoS currents 20120702 |
Optimal dosages of fluoxetine in the treatment of hypoxic brain injury induced by 3-nitropropionic acid: implications for the adjunctive treatment of patients after acute ischemic stroke. | CNS neuroscience & therapeutics 20120701 |
Beta-carboline alkaloids derived from the ascidian Synoicum sp. | Bioorganic & medicinal chemistry 20120701 |
Transport augmentation through the blood-inner ear barriers of guinea pigs treated with 3-nitropropionic acid and patients with acute hearing loss, visualized with 3.0 T MRI: figure labeling clarification. | Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20120701 |
Dithiol-based compounds maintain expression of antioxidant protein peroxiredoxin 1 that counteracts toxicity of mutant huntingtin. | The Journal of biological chemistry 20120629 |
The dopaminergic stabilizer, (-)-OSU6162, rescues striatal neurons with normal and expanded polyglutamine chains in huntingtin protein from exposure to free radicals and mitochondrial toxins. | Brain research 20120612 |
Lack of Jun-N-terminal kinase 3 (JNK3) does not protect against neurodegeneration induced by 3-nitropropionic acid. | Neuropathology and applied neurobiology 20120601 |
Genomic insights to SAR86, an abundant and uncultivated marine bacterial lineage. | The ISME journal 20120601 |
Effect of pesticides on the aggregation of mutant huntingtin protein. | Molecular neurobiology 20120601 |
Collapsin response mediator protein-2 phosphorylation promotes the reversible retraction of oligodendrocyte processes in response to non-lethal oxidative stress. | Journal of neurochemistry 20120601 |
Neuroprotective effects of extremely low-frequency electromagnetic fields on a Huntington's disease rat model: effects on neurotrophic factors and neuronal density. | Neuroscience 20120503 |
Selective mGluR1 antagonist EMQMCM inhibits the kainate-induced excitotoxicity in primary neuronal cultures and in the rat hippocampus. | Neurotoxicity research 20120501 |
Myeloperoxidase inhibition ameliorates multiple system atrophy-like degeneration in a transgenic mouse model. | Neurotoxicity research 20120501 |
Induction of thioredoxin-interacting protein is mediated by oxidative stress, calcium, and glucose after brain injury in mice. | Neurobiology of disease 20120501 |
pH as a biomarker of neurodegeneration in Huntington's disease: a translational rodent-human MRS study. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120501 |
c-Jun-dependent sulfiredoxin induction mediates BDNF protection against mitochondrial inhibition in rat cortical neurons. | Neurobiology of disease 20120501 |
A novel activity for fungal nitronate monooxygenase: detoxification of the metabolic inhibitor propionate-3-nitronate. | Archives of biochemistry and biophysics 20120501 |
Pretreatment with Bacopa monnieri extract offsets 3-nitropropionic acid induced mitochondrial oxidative stress and dysfunctions in the striatum of prepubertal mouse brain. | Canadian journal of physiology and pharmacology 20120501 |
Probucol modulates oxidative stress and excitotoxicity in Huntington's disease models in vitro. | Brain research bulletin 20120310 |
γ-Glutamylcysteine detoxifies reactive oxygen species by acting as glutathione peroxidase-1 cofactor. | Nature communications 20120306 |
Modeling mitochondrial dysfunctions in the brain: from mice to men. | Journal of inherited metabolic disease 20120301 |
Isoform-specific toxicity of Mecp2 in postmitotic neurons: suppression of neurotoxicity by FoxG1. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20120222 |
Compromised mitochondrial complex II in models of Machado-Joseph disease. | Biochimica et biophysica acta 20120201 |
Oral solubilized ursodeoxycholic acid therapy in amyotrophic lateral sclerosis: a randomized cross-over trial. | Journal of Korean medical science 20120201 |
Glycogen accumulation in cardiomyocytes and cardiotoxic effects after 3NPA treatment. | Bosnian journal of basic medical sciences 20120201 |
Real-time molecular imaging of tricarboxylic acid cycle metabolism in vivo by hyperpolarized 1-(13)C diethyl succinate. | Journal of the American Chemical Society 20120118 |
Possible GABAergic mechanism in the neuroprotective effect of gabapentin and lamotrigine against 3-nitropropionic acid induced neurotoxicity. | European journal of pharmacology 20120115 |
Bioactive lipids from the sponge Spirastrella abata. | Bioorganic & medicinal chemistry letters 20120115 |
Downregulation of miR-199a may play a role in 3-nitropropionic acid induced ischemic tolerance in rat brain. | Brain research 20120106 |
Early alterations of brain cellular energy homeostasis in Huntington disease models. | The Journal of biological chemistry 20120106 |
Peroxisome proliferator-activated receptor-α activation attenuates 3-nitropropionic acid induced behavioral and biochemical alterations in rats: possible neuroprotective mechanisms. | European journal of pharmacology 20120105 |
Phytochemical characteristics, free radical scavenging activities, and neuroprotection of five medicinal plant extracts. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
Effect of activation of canonical Wnt signaling by the Wnt-3a protein on the susceptibility of PC12 cells to oxidative and apoptotic insults. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20120101 |
Nucleic Acid-Based Therapy Approaches for Huntington's Disease. | Neurology research international 20120101 |
N-Acetylcysteine reverses mitochondrial dysfunctions and behavioral abnormalities in 3-nitropropionic acid-induced Huntington's disease. | Neuro-degenerative diseases 20120101 |
Bmi1 is down-regulated in the aging brain and displays antioxidant and protective activities in neurons. | PloS one 20120101 |
Quinolinic Acid, an endogenous molecule combining excitotoxicity, oxidative stress and other toxic mechanisms. | International journal of tryptophan research : IJTR 20120101 |
Uncoupling protein-4 (UCP4) increases ATP supply by interacting with mitochondrial Complex II in neuroblastoma cells. | PloS one 20120101 |
α-Mangostin induces apoptosis and suppresses differentiation of 3T3-L1 cells via inhibiting fatty acid synthase. | PloS one 20120101 |
N-acetylcysteine protects against apoptosis through modulation of group I metabotropic glutamate receptor activity. | PloS one 20120101 |
Blood-brain barrier abnormalities caused by HIV-1 gp120: mechanistic and therapeutic implications. | TheScientificWorldJournal 20120101 |
Disruption of the serotonergic system after neonatal hypoxia-ischemia in a rodent model. | Neurology research international 20120101 |
PPARγ and Oxidative Stress: Con(β) Catenating NRF2 and FOXO. | PPAR research 20120101 |
Beneficial effect of (-)schisandrin B against 3-nitropropionic acid-induced cell death in PC12 cells. | BioFactors (Oxford, England) 20120101 |
The ketogenic diet as a treatment paradigm for diverse neurological disorders. | Frontiers in pharmacology 20120101 |
Restoration of the striatal circuitry: from developmental aspects toward clinical applications. | Frontiers in cellular neuroscience 20120101 |
Mitochondria: redox metabolism and dysfunction. | Biochemistry research international 20120101 |
Influence of nanomaterials on stem cell differentiation: designing an appropriate nanobiointerface. | International journal of nanomedicine 20120101 |
Centella asiatica (L.) Urban: From Traditional Medicine to Modern Medicine with Neuroprotective Potential. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
Schisandrin B as a hormetic agent for preventing age-related neurodegenerative diseases. | Oxidative medicine and cellular longevity 20120101 |
The antioxidant mechanisms underlying the aged garlic extract- and S-allylcysteine-induced protection. | Oxidative medicine and cellular longevity 20120101 |
Genetic ablation of Nrf2/antioxidant response pathway in Alexander disease mice reduces hippocampal gliosis but does not impact survival. | PloS one 20120101 |
Reversal of reserpine-induced orofacial dyskinesia and catalepsy by Nardostachys jatamansi. | Indian journal of pharmacology 20120101 |
DYT1 knock-in mice are not sensitized against mitochondrial complex-II inhibition. | PloS one 20120101 |
Functional genomic screen and network analysis reveal novel modifiers of tauopathy dissociated from tau phosphorylation. | Human molecular genetics 20111215 |
Neuronal apoptosis in the striatum of rats treated with 3-nitropropionic acid is not triggered by cell-cycle re-entry. | Neurotoxicology 20111201 |
Melatonin improves 3-nitropropionic acid induced behavioral alterations and neurotrophic factors levels. | Progress in neuro-psychopharmacology & biological psychiatry 20111201 |
Neuroprotective effect of naringin, a dietary flavonoid against 3-nitropropionic acid-induced neuronal apoptosis. | Neurochemistry international 20111201 |
Synthesis and antimicrobial activity of brominated resorcinol dimers. | Bioorganic & medicinal chemistry letters 20111201 |
The effect of Ginkgo biloba extract on 3-nitropropionic acid-induced neurotoxicity in rats. | Neurochemistry international 20111101 |
Functional changes in postsynaptic adenosine A(2A) receptors during early stages of a rat model of Huntington disease. | Experimental neurology 20111101 |
Postnatal development of tyrosine hydroxylase mRNA-expressing neurons in mouse neostriatum. | The European journal of neuroscience 20111101 |
Late-phase recovery in the cochlear lateral wall following severe degeneration by acute energy failure. | Brain research 20111024 |
Novel protective mechanisms of antidepressants against 3-nitropropionic acid induced Huntington's-like symptoms: a comparative study. | Journal of psychopharmacology (Oxford, England) 20111001 |
FK506 ameliorates cell death features in Huntington's disease striatal cell models. | Neurochemistry international 20111001 |
Is neurodegenerative disease a long-latency response to early-life genotoxin exposure? | International journal of environmental research and public health 20111001 |
Synthesis of various 3-nitropropionamides as Mycobacterium tuberculosis isocitrate lyase inhibitor. | Bioorganic & medicinal chemistry letters 20110915 |
Engrailed protects mouse midbrain dopaminergic neurons against mitochondrial complex I insults. | Nature neuroscience 20110904 |
Role of LOX/COX pathways in 3-nitropropionic acid-induced Huntington's disease-like symptoms in rats: protective effect of licofelone. | British journal of pharmacology 20110901 |
Neuroprotective effects of phytocannabinoid-based medicines in experimental models of Huntington's disease. | Journal of neuroscience research 20110901 |
Modeling synergistic drug inhibition of Mycobacterium tuberculosis growth in murine macrophages. | Molecular bioSystems 20110901 |
Sesterterpenes from the tropical sponge Coscinoderma sp. | Journal of natural products 20110826 |
Both stereoselective (R)- and (S)-1-Methyl-1,2,3,4-tetrahydroisoquinoline enantiomers protect striatal terminals against rotenone-induced suppression of dopamine release. | Neurotoxicity research 20110801 |
Role of matrix metalloproteinase-9 (MMP-9) in striatal blood-brain barrier disruption in a 3-nitropropionic acid model of Huntington's disease. | Neuropathology and applied neurobiology 20110801 |
Protective effect of melatonin on 3-NP induced striatal interneuron injury in rats. | Neurochemistry international 20110801 |
Metabolic agents that enhance ATP can improve cognitive functioning: a review of the evidence for glucose, oxygen, pyruvate, creatine, and L-carnitine. | Nutrients 20110801 |
Hypoxia-inducible factor directs POMC gene to mediate hypothalamic glucose sensing and energy balance regulation. | PLoS biology 20110701 |
Mitogen- and stress-activated protein kinase 1-induced neuroprotection in Huntington's disease: role on chromatin remodeling at the PGC-1-alpha promoter. | Human molecular genetics 20110615 |
Recent advances in the genetics of SDH-related paraganglioma and pheochromocytoma. | Familial cancer 20110601 |
Evaluation of the physical and in vitro protective activity of three synthetic peptides derived from the pro- and mature GDNF sequence. | Neuropeptides 20110601 |
The Interface between Cytoskeletal Aberrations and Mitochondrial Dysfunction in Alzheimer's Disease and Related Disorders. | Experimental neurobiology 20110601 |
Protective effect of pioglitazone, a PPARγ ligand, in a 3 nitropropionic acid model of Huntington's disease. | Brain research bulletin 20110530 |
Preferential interneuron survival in the transition zone of 3-NP-induced striatal injury in rats. | Journal of neuroscience research 20110501 |
The herbal preparation Padma® 28 protects against neurotoxicity in PC12 cells. | Phytotherapy research : PTR 20110501 |
Neuroprotective effects of creatine. | Amino acids 20110501 |
NR2B subunit blockade does not affect motor symptoms induced by 3-nitropropionic acid. | Neurological research 20110501 |
Olive oil reduces oxidative damage in a 3-nitropropionic acid-induced Huntington's disease-like rat model. | Nutritional neuroscience 20110501 |
Scalarane sesterterpenes from the sponge Hyatella sp. | Journal of natural products 20110425 |
Acute and long-term response of dopamine nigrostriatal synapses to a single, low-dose episode of 3-nitropropionic acid-mediated chemical hypoxia. | Synapse (New York, N.Y.) 20110401 |
Low doses of 3-nitropropionic acid in vivo induce damage in mouse skeletal muscle. | Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20110401 |
Metabolic profiling of 3-nitropropionic acid early-stage Huntington's disease rat model using gas chromatography time-of-flight mass spectrometry. | Journal of proteome research 20110401 |
Sargachromanols as inhibitors of Na+/K+ ATPase and isocitrate lyase. | Bioorganic & medicinal chemistry letters 20110401 |
Evolution meets disease: penetrance and functional epistasis of mitochondrial tRNA mutations. | PLoS genetics 20110401 |
Mesenchymal stem cell transplantation and DMEM administration in a 3NP rat model of Huntington's disease: morphological and behavioral outcomes. | Behavioural brain research 20110301 |
Acetyl-L-Carnitine Modulates TP53 and IL10 Gene Expression Induced by 3-NPA Evoked Toxicity in PC12 Cells. | Current neuropharmacology 20110301 |
Bacopa monnieri modulates endogenous cytoplasmic and mitochondrial oxidative markers in prepubertal mice brain. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20110215 |
Erythropoietin is neuroprotective in a transgenic mouse model of multiple system atrophy. | Movement disorders : official journal of the Movement Disorder Society 20110215 |
Transport augmentation through the blood-inner ear barriers of guinea pigs treated with 3-nitropropionic acid and patients with acute hearing loss, visualized with 3.0 T MRI. | Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20110201 |
Frataxin participates to the hypoxia-induced response in tumors. | Cell death & disease 20110201 |
Geometric restraint drives on- and off-pathway catalysis by the Escherichia coli menaquinol:fumarate reductase. | The Journal of biological chemistry 20110128 |
Chemical preconditioning-induced reactive astrocytosis contributes to the reduction of post-ischemic edema through aquaporin-4 downregulation. | Experimental neurology 20110101 |
Flexible metabolism in Metarhizium anisopliae and Beauveria bassiana: role of the glyoxylate cycle during insect pathogenesis. | Microbiology (Reading, England) 20110101 |
Biochemical and biophysical characterization of succinate: quinone reductase from Thermus thermophilus. | Biochimica et biophysica acta 20110101 |
Altered microRNA regulation in Huntington's disease models. | Experimental neurology 20110101 |
Neuroprotective effect of human mesenchymal stem cells in an animal model of double toxin-induced multiple system atrophy parkinsonism. | Cell transplantation 20110101 |
Novel isatinyl thiosemicarbazones derivatives as potential molecule to combat HIV-TB co-infection. | European journal of medicinal chemistry 20110101 |
Differential patterns of histone acetylation in inflammatory bowel diseases. | Journal of inflammation (London, England) 20110101 |
Resistance to MPTP-neurotoxicity in α-synuclein knockout mice is complemented by human α-synuclein and associated with increased β-synuclein and Akt activation. | PloS one 20110101 |
Isolation and characterization of a Mn(II)-oxidizing Bacillus strain from the demosponge Suberites domuncula. | Marine drugs 20110101 |
The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease. | International journal of molecular sciences 20110101 |
The Nrf2/ARE Pathway: A Promising Target to Counteract Mitochondrial Dysfunction in Parkinson's Disease. | Parkinson's disease 20110101 |
Altered dopamine and serotonin metabolism in motorically asymptomatic R6/2 mice. | PloS one 20110101 |
Mitochondrial dysfunction, metabolic deficits, and increased oxidative stress in Huntington's disease. | Chang Gung medical journal 20110101 |
Forebrain striatal-specific expression of mutant huntingtin protein in vivo induces cell-autonomous age-dependent alterations in sensitivity to excitotoxicity and mitochondrial function. | ASN neuro 20110101 |
The antioxidative effect of electro-acupuncture in a mouse model of Parkinson's disease. | PloS one 20110101 |
Antifungal activity of redox-active benzaldehydes that target cellular antioxidation. | Annals of clinical microbiology and antimicrobials 20110101 |
Melatonin in mitochondrial dysfunction and related disorders. | International journal of Alzheimer's disease 20110101 |
Impairment of adult hippocampal neural progenitor proliferation by methamphetamine: role for nitrotyrosination. | Molecular brain 20110101 |
A new drug design targeting the adenosinergic system for Huntington's disease. | PloS one 20110101 |
Nitric oxide modulation in protective role of antidepressants against chronic fatigue syndrome in mice. | Indian journal of pharmacology 20110101 |
Altered Balance of Activity in the Striatal Direct and Indirect Pathways in Mouse Models of Huntington's Disease. | Frontiers in systems neuroscience 20110101 |
On the antioxidant properties of kynurenic acid: free radical scavenging activity and inhibition of oxidative stress. | Neurotoxicology and teratology 20110101 |
Transforming Growth Factor-Beta Signaling in the Neural Stem Cell Niche: A Therapeutic Target for Huntington's Disease. | Neurology research international 20110101 |
Peroxisome proliferator activator receptor gamma coactivator-1alpha (PGC-1α) improves motor performance and survival in a mouse model of amyotrophic lateral sclerosis. | Molecular neurodegeneration 20110101 |
Decreased striatal RGS2 expression is neuroprotective in Huntington's disease (HD) and exemplifies a compensatory aspect of HD-induced gene regulation. | PloS one 20110101 |
Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy. | BMC cancer 20110101 |
A combination of compositional index and genetic algorithm for predicting transmembrane helical segments. | PloS one 20110101 |
C-Jun N-terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress. | Molecular neurodegeneration 20110101 |
Asiatic acid inhibits pro-angiogenic effects of VEGF and human gliomas in endothelial cell culture models. | PloS one 20110101 |
GSK-3 as a Target for Lithium-Induced Neuroprotection Against Excitotoxicity in Neuronal Cultures and Animal Models of Ischemic Stroke. | Frontiers in molecular neuroscience 20110101 |
Motor deficits and decreased striatal dopamine receptor 2 binding activity in the striatum-specific Dyt1 conditional knockout mice. | PloS one 20110101 |
D-β-hydroxybutyrate is protective in mouse models of Huntington's disease. | PloS one 20110101 |
Tauroursodeoxycholic acid (TUDCA) protects photoreceptors from cell death after experimental retinal detachment. | PloS one 20110101 |
The role of manganese superoxide dismutase in inflammation defense. | Enzyme research 20110101 |
Metabolic pathway and distribution of superparamagnetic iron oxide nanoparticles: in vivo study. | International journal of nanomedicine 20110101 |
Iron insufficiency compromises motor neurons and their mitochondrial function in Irp2-null mice. | PloS one 20110101 |
Huntington's Disease and Striatal Signaling. | Frontiers in neuroanatomy 20110101 |
Anti-neuroinflammatory effects of the extract of Achillea fragrantissima. | BMC complementary and alternative medicine 20110101 |
Manganese superoxide dismutase: guardian of the powerhouse. | International journal of molecular sciences 20110101 |
Both pre- and postsynaptic activity of Nsf prevents degeneration of hair-cell synapses. | PloS one 20110101 |
The promise of neuroprotective agents in Parkinson's disease. | Frontiers in neurology 20110101 |
Effect of polyphenols on oxidative stress and mitochondrial dysfunction in neuronal death and brain edema in cerebral ischemia. | International journal of molecular sciences 20110101 |
Oxidative stress in neurodegenerative diseases: mechanisms and therapeutic perspectives. | Oxidative medicine and cellular longevity 20110101 |
System-level strategies for studying the metabolism of Mycobacterium tuberculosis. | Molecular bioSystems 20101208 |
Calcium signalling-dependent mitochondrial dysfunction and bioenergetics regulation in respiratory chain Complex II deficiency. | Cell death and differentiation 20101201 |
Metabolic activity of the subthalamic nucleus in a primate model of L-dopa-unresponsive parkinsonism. | Neurological research 20101201 |
Pyruvate carboxylation in different model systems studied by (13)C MRS. | Neurochemical research 20101201 |
Protective effects of TRH and its analogues against various cytotoxic agents in retinoic acid (RA)-differentiated human neuroblastoma SH-SY5Y cells. | Neuropeptides 20101201 |
Synthetic analogs of indole-containing natural products as inhibitors of sortase A and isocitrate lyase. | Bioorganic & medicinal chemistry letters 20101201 |
Mitochondrial fission and cristae disruption increase the response of cell models of Huntington's disease to apoptotic stimuli. | EMBO molecular medicine 20101201 |
Mechanisms and prospects of ischemic tolerance induced by cerebral preconditioning. | International neurourology journal 20101201 |
Mutant huntingtin alters cell fate in response to microtubule depolymerization via the GEF-H1-RhoA-ERK pathway. | The Journal of biological chemistry 20101126 |
Bromophenols as Candida albicans isocitrate lyase inhibitors. | Bioorganic & medicinal chemistry letters 20101115 |
Lycopene prevents 3-nitropropionic acid-induced mitochondrial oxidative stress and dysfunctions in nervous system. | Neurochemistry international 20101101 |
Possible nitric oxide modulation in protective effect of FK-506 against 3-nitropropionic acid-induced behavioral, oxidative, neurochemical, and mitochondrial alterations in rat brain. | Drug and chemical toxicology 20101001 |
Erythropoietin and sonic hedgehog mediate the neuroprotective effects of brain-derived neurotrophic factor against mitochondrial inhibition. | Neurobiology of disease 20101001 |
Brain region specificity of 3-nitropropionic acid-induced vulnerability of neurons involves cytochrome c oxidase. | Neurochemistry international 20101001 |
Kainic acid and 3-Nitropropionic acid induced expression of laminin in vascular elements of the rat brain. | Brain research 20100917 |
Androgens selectively protect against apoptosis in hippocampal neurones. | Journal of neuroendocrinology 20100901 |
Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease. | EMBO molecular medicine 20100901 |
The ASK1-Signalosome regulates p38 MAPK activity in response to levels of endogenous oxidative stress in the Klotho mouse models of aging. | Aging 20100901 |
The role of mitochondria in brain aging and the effects of melatonin. | Current neuropharmacology 20100901 |
Assessment of 3-nitropropionic acid-evoked peripheral neuropathy in rats: neuroprotective effects of acetyl-l-carnitine and resveratrol. | Neuroscience letters 20100816 |
Regulation of GSK-3beta by calpain in the 3-nitropropionic acid model. | Hippocampus 20100801 |
Complex I: inhibitors, inhibition and neurodegeneration. | Experimental neurology 20100801 |
Delayed pre-conditioning by 3-nitropropionic acid prevents 3,4-methylenedioxymetamphetamine-induced 5-HT deficits. | Journal of neurochemistry 20100801 |
5-Nitro-2-furoic acid hydrazones: design, synthesis and in vitro antimycobacterial evaluation against log and starved phase cultures. | Bioorganic & medicinal chemistry letters 20100801 |
Nutrient withdrawal rescues growth factor-deprived cells from mTOR-dependent damage. | Aging 20100801 |
Protective effect of sesamol against 3-nitropropionic acid-induced cognitive dysfunction and altered glutathione redox balance in rats. | Basic & clinical pharmacology & toxicology 20100701 |
Identification of novel 1,4-benzoxazine compounds that are protective in tissue culture and in vivo models of neurodegeneration. | Journal of neuroscience research 20100701 |
Ketones prevent synaptic dysfunction induced by mitochondrial respiratory complex inhibitors. | Journal of neurochemistry 20100701 |
Cystamine protects from 3-nitropropionic acid lesioning via induction of nf-e2 related factor 2 mediated transcription. | Experimental neurology 20100701 |
Mechanisms underlying striatal vulnerability to 3-nitropropionic acid. | Journal of neurochemistry 20100701 |
Brain region-specific vulnerability of astrocytes in response to 3-nitropropionic acid is mediated by cytochrome c oxidase isoform expression. | Cell and tissue research 20100701 |
Neuroprotective mechanisms of brain-derived neurotrophic factor against 3-nitropropionic acid toxicity: therapeutic implications for Huntington's disease. | Annals of the New York Academy of Sciences 20100701 |
Lithium reduces apoptosis and autophagy after neonatal hypoxia-ischemia. | Cell death & disease 20100701 |
Prophylaxis with Centella asiatica confers protection to prepubertal mice against 3-nitropropionic-acid-induced oxidative stress in brain. | Phytotherapy research : PTR 20100601 |
FoxO1 is involved in the antineoplastic effect of calorie restriction. | Aging cell 20100601 |
Geranylgeranylacetone ameliorates acute cochlear damage caused by 3-nitropropionic acid. | Neurotoxicology 20100601 |
Mitochondrial matters of the brain: the role in Huntington's disease. | Journal of bioenergetics and biomembranes 20100601 |
Dysregulation of CREB activation and histone acetylation in 3-nitropropionic acid-treated cortical neurons: prevention by BDNF and NGF. | Neurotoxicity research 20100501 |
Balance dysfunction resulting from acute inner ear energy failure is caused primarily by vestibular hair cell damage. | Journal of neuroscience research 20100501 |
Sildenafil protects against 3-nitropropionic acid neurotoxicity through the modulation of calpain, CREB, and BDNF. | Neurobiology of disease 20100501 |
Nitric oxide mechanism in the protective effect of antidepressants against 3-nitropropionic acid-induced cognitive deficit, glutathione and mitochondrial alterations in animal model of Huntington's disease. | Behavioural pharmacology 20100501 |
Alpha-synuclein deficient mice are resistant to toxin-induced multiple system atrophy. | Neuroreport 20100421 |
Opening of the mitoKATP channel and decoupling of mitochondrial complex II and III contribute to the suppression of myocardial reperfusion hyperoxygenation. | Molecular and cellular biochemistry 20100401 |
Mitochondrial-dependent apoptosis in Huntington's disease human cybrids. | Experimental neurology 20100401 |
Hypoxia sensing in the fetal chicken femoral artery is mediated by the mitochondrial electron transport chain. | American journal of physiology. Regulatory, integrative and comparative physiology 20100401 |
Mitochondrial quality control and neurological disease: an emerging connection. | Expert reviews in molecular medicine 20100401 |
HIF prolyl hydroxylase inhibitors prevent neuronal death induced by mitochondrial toxins: therapeutic implications for Huntington's disease and Alzheimer's disease. | Antioxidants & redox signaling 20100215 |
3-nitropropionic acid-induced mitochondrial permeability transition: comparative study of mitochondria from different tissues and brain regions. | Journal of neuroscience research 20100215 |
3-Nitropropionic acid as a tool to study the mechanisms involved in Huntington's disease: past, present and future. | Molecules (Basel, Switzerland) 20100210 |
Systemic administration of 3-nitropropionic acid points out a different role for active caspase-3 in neurons and astrocytes. | Neurochemistry international 20100201 |
Enhanced expression of C/EBP homologous protein (CHOP) precedes degeneration of fibrocytes in the lateral wall after acute cochlear mitochondrial dysfunction induced by 3-nitropropionic acid. | Neurochemistry international 20100201 |
Protective effect of hesperidin and naringin against 3-nitropropionic acid induced Huntington's like symptoms in rats: possible role of nitric oxide. | Behavioural brain research 20100105 |
Trolox ameliorates 3-nitropropionic acid-induced neurotoxicity in rats. | Neurotoxicology and teratology 20100101 |
Protective effect of tert-butylhydroquinone on the quinolinic-acid-induced toxicity in rat striatal slices: role of the Nrf2-antioxidant response element pathway. | Neuro-Signals 20100101 |
Discriminative behavioral assessment unveils remarkable reactive astrocytosis and early molecular correlates in basal ganglia of 3-nitropropionic acid subchronic treated rats. | Neurochemistry international 20100101 |
Promethazine protects against 3-nitropropionic acid-induced neurotoxicity. | Neurochemistry international 20100101 |
Pyrroloquinoline quinone stimulates mitochondrial biogenesis through cAMP response element-binding protein phosphorylation and increased PGC-1alpha expression. | The Journal of biological chemistry 20100101 |
Antioxidant strategy to rescue synaptosomes from oxidative damage and energy failure in neurotoxic models in rats: protective role of S-allylcysteine. | Journal of neural transmission (Vienna, Austria : 1996) 20100101 |
Electrophysiological actions of zonisamide on striatal neurons: Selective neuroprotection against complex I mitochondrial dysfunction. | Experimental neurology 20100101 |
Apolipoprotein E genotype and hepatitis C, HIV and herpes simplex disease risk: a literature review. | Lipids in health and disease 20100101 |
Reduction of beta-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease. | Journal of neuroinflammation 20100101 |
Preconditioning-induced ischemic tolerance: a window into endogenous gearing for cerebroprotection. | Experimental & translational stroke medicine 20100101 |
Time-course correlation of early toxic events in three models of striatal damage: modulation by proteases inhibition. | Neurochemistry international 20100101 |
Comprehensive behavioral testing in the R6/2 mouse model of Huntington's disease shows no benefit from CoQ10 or minocycline. | PloS one 20100101 |
Genetic mouse models of Huntington's disease: focus on electrophysiological mechanisms. | ASN neuro 20100101 |
The bright and the dark sides of DNA repair in stem cells. | Journal of biomedicine & biotechnology 20100101 |
Uncoupling oxidative/energy metabolism with low sub chronic doses of 3-nitropropionic acid or iodoacetate in vivo produces striatal cell damage. | International journal of biological sciences 20100101 |
Cyclosporine A attenuates 3-nitropropionic acid-induced Huntington-like symptoms in rats: possible nitric oxide mechanism. | International journal of toxicology 20100101 |
Alterations in striatal synaptic transmission are consistent across genetic mouse models of Huntington's disease. | ASN neuro 20100101 |
Oxidative stress induced in rat brain by a combination of 3-nitropropionic acid and global ischemia. | International journal of clinical and experimental medicine 20100101 |
Effects of mitochondrial dysfunction on the immunological properties of microglia. | Journal of neuroinflammation 20100101 |
Mitochondrial preconditioning: a potential neuroprotective strategy. | Frontiers in aging neuroscience 20100101 |
PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration. | Cell communication and signaling : CCS 20100101 |
Tryptophan, Neurodegeneration and HIV-Associated Neurocognitive Disorder. | International journal of tryptophan research : IJTR 20100101 |
An investigation of the neuroprotective effects of Curcumin in a model of Homocysteine - induced oxidative stress in the rat's brain. | Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20100101 |
Delayed onset of the diurnal melatonin rise in patients with Huntington's disease. | Journal of neurology 20091201 |
Down-regulation of Bcl-2 enhances autophagy activation and cell death induced by mitochondrial dysfunction in rat striatum. | Journal of neuroscience research 20091201 |
Protective effects of epigallocatechin gallate following 3-nitropropionic acid-induced brain damage: possible nitric oxide mechanisms. | Psychopharmacology 20091201 |
Altered open field behavior in rats induced by acute administration of 3-nitropropionic acid: possible glutamatergic and dopaminergic involvement. | Acta biologica Hungarica 20091201 |
Cyclopiazonic acid biosynthesis of Aspergillus flavus and Aspergillus oryzae. | Toxins 20091201 |
Lycopene modulates nitric oxide pathways against 3-nitropropionic acid-induced neurotoxicity. | Life sciences 20091104 |
Cytochrome c oxidase isoform IV-2 is involved in 3-nitropropionic acid-induced toxicity in striatal astrocytes. | Glia 20091101 |
Striatal dopamine level contributes to hydroxyl radical generation and subsequent neurodegeneration in the striatum in 3-nitropropionic acid-induced Huntington's disease in rats. | Neurochemistry international 20091101 |
CREB is a key regulator of striatal vulnerability in chemical and genetic models of Huntington's disease. | Neurobiology of disease 20091101 |
Mice deficient in dihydrolipoyl succinyl transferase show increased vulnerability to mitochondrial toxins. | Neurobiology of disease 20091101 |
An anaerobic-type alpha-ketoglutarate ferredoxin oxidoreductase completes the oxidative tricarboxylic acid cycle of Mycobacterium tuberculosis. | PLoS pathogens 20091101 |
Induction of heat shock protein 70 reduces the alteration of striatal electrical activity caused by mitochondrial impairment. | Neuroscience 20091020 |
Preconditioning with 4-aminopyridine protects cerebellar granule neurons against excitotoxicity. | Brain research 20091019 |
Mitochondrial dynamics--fusion, fission, movement, and mitophagy--in neurodegenerative diseases. | Human molecular genetics 20091015 |
Effect of lycopene and epigallocatechin-3-gallate against 3-nitropropionic acid induced cognitive dysfunction and glutathione depletion in rat: a novel nitric oxide mechanism. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20091001 |
Excitotoxic motoneuron degeneration induced by glutamate receptor agonists and mitochondrial toxins in organotypic cultures of chick embryo spinal cord. | The Journal of comparative neurology 20091001 |
Kaempferol protects against rat striatal degeneration induced by 3-nitropropionic acid. | Journal of neurochemistry 20091001 |
Diminished hippocalcin expression in Huntington's disease brain does not account for increased striatal neuron vulnerability as assessed in primary neurons. | Journal of neurochemistry 20091001 |
ROS scavenging capacity and neuroprotective effect of alpha-mangostin against 3-nitropropionic acid in cerebellar granule neurons. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20090901 |
Mitochondrial inhibitor 3-nitroproprionic acid enhances oxidative modification of alpha-synuclein in a transgenic mouse model of multiple system atrophy. | Journal of neuroscience research 20090901 |
BDNF regulates BIM expression levels in 3-nitropropionic acid-treated cortical neurons. | Neurobiology of disease 20090901 |
Involvement of nitric oxide in 3-nitropropionic acid-induced depression of spinal reflexes in neonatal rat spinal cord in vitro. | European journal of pharmacology 20090901 |
Anaerobic central metabolic pathways active during polyhydroxyalkanoate production in uncultured cluster 1 Defluviicoccus enriched in activated sludge communities. | FEMS microbiology letters 20090901 |
Induction of membrane permeability in Escherichia coli mediated by lysis protein of the ColE7 operon. | FEMS microbiology letters 20090901 |
Protective role of sertraline against 3-nitropropionic acid-induced cognitive dysfunction and redox ratio in striatum, cortex and hippocampus of rat brain. | Indian journal of experimental biology 20090901 |
Neuroprotective effect of carvedilol and melatonin on 3-nitropropionic acid-induced neurotoxicity in neuroblastoma. | Journal of physiology and biochemistry 20090901 |
Dermal fibroblasts from long-lived Ames dwarf mice maintain their in vivo resistance to mitochondrial generated reactive oxygen species (ROS). | Aging 20090901 |
Adenosine, ketogenic diet and epilepsy: the emerging therapeutic relationship between metabolism and brain activity. | Current neuropharmacology 20090901 |
In vitro antioxidant activity of Valeriana officinalis against different neurotoxic agents. | Neurochemical research 20090801 |
Protective effect of rivastigmine against 3-nitropropionic acid-induced Huntington's disease like symptoms: possible behavioural, biochemical and cellular alterations. | European journal of pharmacology 20090801 |
Early nerve ending rescue from oxidative damage and energy failure by L: -carnitine as post-treatment in two neurotoxic models in rat: recovery of antioxidant and reductive capacities. | Experimental brain research 20090801 |
Sonic hedgehog mediates BDNF-induced neuroprotection against mitochondrial inhibitor 3-nitropropionic acid. | Biochemical and biophysical research communications 20090717 |
In vivo dopamine release and uptake impairments in rats treated with 3-nitropropionic acid. | Neuroscience 20090707 |
Metabonomic characterization of the 3-nitropropionic acid rat model of Huntington's disease. | Neurochemical research 20090701 |
Protective effects of brain-derived neurotrophic factor against neurotoxicity of 3-nitropropionic acid in rat cortical neurons. | Neurotoxicology 20090701 |
The brain uncoupling protein UCP4 attenuates mitochondrial toxin-induced cell death: role of extracellular signal-regulated kinases in bioenergetics adaptation and cell survival. | Neurotoxicity research 20090701 |
Heme oxygenase-1 induction prevents neuronal damage triggered during mitochondrial inhibition: role of CO and bilirubin. | The international journal of biochemistry & cell biology 20090601 |
A mouse model for degeneration of the spiral ligament. | Journal of the Association for Research in Otolaryngology : JARO 20090601 |
Complex II inhibition by 3-NP causes mitochondrial fragmentation and neuronal cell death via an NMDA- and ROS-dependent pathway. | Cell death and differentiation 20090601 |
Whole body hyperthermia reduces oxidative stress in the striatum of rats in an animal model of mitochondrial toxicity with 3-nitropropionic acid. | International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 20090601 |
Combination therapy with coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson's and Huntington's diseases. | Journal of neurochemistry 20090601 |
Site-directed mutagenesis, kinetic and inhibition studies of aspartate ammonia lyase from Bacillus sp. YM55-1. | The FEBS journal 20090601 |
Possible neuroprotective effect of Withania somnifera root extract against 3-nitropropionic acid-induced behavioral, biochemical, and mitochondrial dysfunction in an animal model of Huntington's disease. | Journal of medicinal food 20090601 |
Targeting oxidative/nitrergic stress ameliorates motor impairment, and attenuates synaptic mitochondrial dysfunction and lipid peroxidation in two models of Huntington's disease. | Behavioural brain research 20090516 |
Antioxidant effects of different extracts from Melissa officinalis, Matricaria recutita and Cymbopogon citratus. | Neurochemical research 20090501 |
Effects of nitrocompounds on uric acid-utilizing microorganisms, nitrogen retention, and microbial community in laying hen manure. | Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20090501 |
GABAergic striatal neurons exhibit caspase-independent, mitochondrially mediated programmed cell death. | Journal of neurochemistry 20090501 |
Mitochondria and energetic depression in cell pathophysiology. | International journal of molecular sciences 20090501 |
No spatial memory deficit exists in Kunming mice that recently recovered from motor defects following 3-nitropropionic acid intoxication. | Neuroscience bulletin 20090401 |
Dual mechanism of brain injury and novel treatment strategy in maple syrup urine disease. | Brain : a journal of neurology 20090401 |
p53 mediates mitochondria dysfunction-triggered autophagy activation and cell death in rat striatum. | Autophagy 20090401 |
[Model of Huntington's disease induced with 3-nitropropionic acid]. | Revista de neurologia 20090401 |
Neuroprotective effect of cyclosporine and FK506 against 3-nitropropionic acid induced cognitive dysfunction and glutathione redox in rat: possible role of nitric oxide. | Neuroscience research 20090401 |
N-methyl-D-aspartate receptor antagonists have variable affect in 3-nitropropionic acid toxicity. | Neurochemical research 20090301 |
Targeting the progression of Parkinson's disease. | Current neuropharmacology 20090301 |
5-Hydroxyindole-type alkaloids, as Candida albicans isocitrate lyase inhibitors, from the tropical sponge Hyrtios sp. | Bioorganic & medicinal chemistry letters 20090215 |
Evidence of calpain/cdk5 pathway inhibition by lithium in 3-nitropropionic acid toxicity in vivo and in vitro. | Neuropharmacology 20090201 |
Exendin-4 improves glycemic control, ameliorates brain and pancreatic pathologies, and extends survival in a mouse model of Huntington's disease. | Diabetes 20090201 |
Impaired mitochondria-dependent vasodilation in cerebral arteries of Zucker obese rats with insulin resistance. | American journal of physiology. Regulatory, integrative and comparative physiology 20090201 |
Possible role of sertraline against 3-nitropropionic acid induced behavioral, oxidative stress and mitochondrial dysfunctions in rat brain. | Progress in neuro-psychopharmacology & biological psychiatry 20090201 |
The natural xanthone alpha-mangostin reduces oxidative damage in rat brain tissue. | Nutritional neuroscience 20090201 |
Mitochondrial dysfunction disrupts trafficking of Kir4.1 in spiral ganglion satellite cells. | Journal of neuroscience research 20090101 |
Old mice present increased levels of succinate dehydrogenase activity and lower vulnerability to dyskinetic effects of 3-nitropropionic acid. | Pharmacology, biochemistry, and behavior 20090101 |
Mitochondrial DNA damage is a hallmark of chemically induced and the R6/2 transgenic model of Huntington's disease. | DNA repair 20090101 |
Nrf2 is critical in defense against high glucose-induced oxidative damage in cardiomyocytes. | Journal of molecular and cellular cardiology 20090101 |
Blood-brain barrier disruption in the striatum of rats treated with 3-nitropropionic acid. | Neurotoxicology 20090101 |
Normal aging modulates the neurotoxicity of mutant huntingtin. | PloS one 20090101 |
Both systemic and local application of granulocyte-colony stimulating factor (G-CSF) is neuroprotective after retinal ganglion cell axotomy. | BMC neuroscience 20090101 |
Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription. | PloS one 20090101 |
IKKalpha and IKKbeta regulation of DNA damage-induced cleavage of huntingtin. | PloS one 20090101 |
Conformational targeting of fibrillar polyglutamine proteins in live cells escalates aggregation and cytotoxicity. | PloS one 20090101 |
Sesamol attenuate 3-nitropropionic acid-induced Huntington-like behavioral, biochemical, and cellular alterations in rats. | Journal of Asian natural products research 20090101 |
A systems biology framework for modeling metabolic enzyme inhibition of Mycobacterium tuberculosis. | BMC systems biology 20090101 |
Genetic and pharmacological inhibition of calcineurin corrects the BDNF transport defect in Huntington's disease. | Molecular brain 20090101 |
Does neuroinflammation fan the flame in neurodegenerative diseases? | Molecular neurodegeneration 20090101 |
Coenzyme Q10 effects in neurodegenerative disease. | Neuropsychiatric disease and treatment 20090101 |
Dopamine D2 receptor stimulation potentiates PolyQ-Huntingtin-induced mouse striatal neuron dysfunctions via Rho/ROCK-II activation. | PloS one 20090101 |
Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis. | Neuron 20081226 |
Galantamine reduces striatal degeneration in 3-nitropropionic acid model of Huntington's disease. | Neuroscience letters 20081219 |
3-Nitropropionic acid-induced depression of spinal reflexes involves mechanisms different from ischemia-induced depression. | Brain research bulletin 20081216 |
Nordihydroguaiaretic acid activates the antioxidant pathway Nrf2/HO-1 and protects cerebellar granule neurons against oxidative stress. | Neuroscience letters 20081212 |
3-Nitropropionic acid-induced depression of spinal reflexes does not involve 5-hydroxytryptaminergic system in contrast to ischemia-induced depression in neonatal rat spinal cord in vitro. | Neuroscience letters 20081203 |
Bcl-2 upregulation after 3-nitropropionic acid preconditioning in warm rat liver ischemia. | Shock (Augusta, Ga.) 20081201 |
Effects of select nitrocompounds on in vitro ruminal fermentation during conditions of limiting or excess added reductant. | Bioresource technology 20081201 |
Mechanism of 3-nitropropionic acid-induced membrane permeability transition of isolated mitochondria and its suppression by L-carnitine. | Cell biochemistry and function 20081201 |
Modulation of alpha-synuclein expression in transgenic animals for modelling synucleinopathies--is the juice worth the squeeze? | Neurotoxicity research 20081201 |
3-Nitropropionic acid depresses spinal reflexes involving GABAergic and glycinergic transmission in neonatal rat spinal cord in vitro. | Life sciences 20081121 |
Effect of Centella asiatica leaf powder on oxidative markers in brain regions of prepubertal mice in vivo and its in vitro efficacy to ameliorate 3-NPA-induced oxidative stress in mitochondria. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20081101 |
Cell cycle activation in striatal neurons from Huntington's disease patients and rats treated with 3-nitropropionic acid. | International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20081101 |
Neurotoxicological effects of 3-nitropropionic acid on the neonatal rat. | Neurotoxicology 20081101 |
Prophylactic neuroprotective property of Centella asiatica against 3-nitropropionic acid induced oxidative stress and mitochondrial dysfunctions in brain regions of prepubertal mice. | Neurotoxicology 20081101 |
Scalarane sesterterpenes from the sponge Smenospongia sp. | Journal of natural products 20081101 |
A role for oxidized DNA precursors in Huntington's disease-like striatal neurodegeneration. | PLoS genetics 20081101 |
A pharmacological MRI assessment of dizocilpine (MK-801) in the 3-nitroproprionic acid-lesioned rat. | Neuroscience letters 20081017 |
Inhibition of Candida albicans isocitrate lyase activity by sesterterpene sulfates from the tropical sponge Dysidea sp. | Bioorganic & medicinal chemistry letters 20081015 |
Increased glucose metabolism and ATP level in brain tissue of Huntington's disease transgenic mice. | The FEBS journal 20081001 |
The mechanism of the late preconditioning effect of 3-nitropropionic acid. | Archives of pharmacal research 20081001 |
Lipid peroxidation, mitochondrial dysfunction and neurochemical and behavioural deficits in different neurotoxic models: protective role of S-allylcysteine. | Free radical research 20081001 |
Brain adaptation to stressful stimuli: a new perspective on potential therapeutic approaches based on BDNF and NMDA receptors. | CNS & neurological disorders drug targets 20081001 |
Miscellaneous. | Indian journal of pharmacology 20081001 |
Decreased striatal dopamine release underlies increased expression of long-term synaptic potentiation at corticostriatal synapses 24 h after 3-nitropropionic-acid-induced chemical hypoxia. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20080917 |
Melatonin combats molecular terrorism at the mitochondrial level. | Interdisciplinary toxicology 20080901 |
Preconditioning with NMDA protects against toxicity of 3-nitropropionic acid or glutamate in cultured cerebellar granule neurons. | Neuroscience letters 20080808 |
Depressive-like behavior in mice recently recovered from motor disorders after 3-nitropropionic acid intoxication. | Neuroscience bulletin 20080801 |
Current approaches to the treatment of Parkinson's disease. | Neuropsychiatric disease and treatment 20080801 |
Modulation of SIRT1 expression in different neurodegenerative models and human pathologies. | Neuroscience 20080717 |
Resistance to kynurenic acid of the NMDA receptor-dependent toxicity of 3-nitropropionic acid and cyanide in cerebellar granule neurons. | Brain research 20080618 |
Responses of differentiated MC3T3-E1 osteoblast-like cells to reactive oxygen species. | European journal of pharmacology 20080610 |
Chemical hypoxia facilitates alternative splicing of EAAT2 in presymptomatic APP23 transgenic mice. | Neurochemical research 20080601 |
Neuroprotection of lamotrigine on hypoxic-ischemic brain damage in neonatal rats: Relations to administration time and doses. | Biologics : targets & therapy 20080601 |
Altered striatal vulnerability to 3-nitropropionic acid in rats due to sex hormone levels during late phase of brain development. | Neuroscience letters 20080516 |
Dopamine determines the vulnerability of striatal neurons to the N-terminal fragment of mutant huntingtin through the regulation of mitochondrial complex II. | Human molecular genetics 20080515 |
Excitotoxic damage, disrupted energy metabolism, and oxidative stress in the rat brain: antioxidant and neuroprotective effects of L-carnitine. | Journal of neurochemistry 20080501 |
Sensory motor mismatch within the supplementary motor area in the dystonic monkey. | Neurobiology of disease 20080501 |
Chemical preconditioning effect of 3-nitropropionic acid in anesthetized rat heart. | Life sciences 20080423 |
NF-kB/NOS cross-talk induced by mitochondrial complex II inhibition: implications for Huntington's disease. | Neuroscience letters 20080404 |
Rasagiline is neuroprotective in a transgenic model of multiple system atrophy. | Experimental neurology 20080401 |
Tiagabine, a GABA uptake inhibitor, attenuates 3-nitropropionic acid-induced alterations in various behavioral and biochemical parameters in rats. | Progress in neuro-psychopharmacology & biological psychiatry 20080401 |
Developmental exposure to polychlorinated biphenyls influences stroke outcome in adult rats. | Environmental health perspectives 20080401 |
Effect of 17beta-estradiol on olfactory bulbectomy-induced oxidative stress and behavioral changes in rats. | Neuropsychiatric disease and treatment 20080401 |
Application of multipotent mesenchymal stromal cells from human adipose tissue for compensation of neurological deficiency induced by 3-nitropropionic Acid in rats. | Bulletin of experimental biology and medicine 20080401 |
Differential involvement of cell cycle reactivation between striatal and cortical neurons in cell death induced by 3-nitropropionic acid. | The Journal of biological chemistry 20080307 |
Atorvastatin attenuates mitochondrial toxin-induced striatal degeneration, with decreasing iNOS/c-Jun levels and activating ERK/Akt pathways. | Journal of neurochemistry 20080301 |
Selective PDE inhibitors rolipram and sildenafil improve object retrieval performance in adult cynomolgus macaques. | Psychopharmacology 20080301 |
Endogenous dopamine enhances the neurotoxicity of 3-nitropropionic acid in the striatum through the increase of mitochondrial respiratory inhibition and free radicals production. | Neurotoxicology 20080301 |
Cytoplasmic calcium mediates oxidative damage in an excitotoxic /energetic deficit synergic model in rats. | The European journal of neuroscience 20080301 |
Preconditioning paradigms and pathways in the brain. | Cleveland Clinic journal of medicine 20080301 |
Regional susceptibility to domoic acid in primary astrocyte cells cultured from the brain stem and hippocampus. | Marine drugs 20080301 |
Protective effect of minocycline, a semi-synthetic second-generation tetracycline against 3-nitropropionic acid (3-NP)-induced neurotoxicity. | Toxicology 20080227 |
Granulocyte-colony stimulating factor attenuates striatal degeneration with activating survival pathways in 3-nitropropionic acid model of Huntington's disease. | Brain research 20080215 |
The impact of mitochondrial energetic dysfunction on apoptosis in outer hair cells of the cochlea following exposure to intense noise. | Hearing research 20080201 |
Induction of apoptosis signal-regulating kinase 1 and oxidative stress mediate age-dependent vulnerability to 3-nitropropionic acid in the mouse striatum. | Neuroscience letters 20080110 |
Caspase inhibitor facilitates recovery of hearing by protecting the cochlear lateral wall from acute cochlear mitochondrial dysfunction. | Journal of neuroscience research 20080101 |
Mitochondrial NAD+-linked State 3 respiration and complex-I activity are compromised in the cerebral cortex of 3-nitropropionic acid-induced rat model of Huntington's disease. | Journal of neurochemistry 20080101 |
Neural stem/progenitor cells initiate the formation of cellular networks that provide neuroprotection by growth factor-modulated antioxidant expression. | Stem cells (Dayton, Ohio) 20080101 |
Neuroinflammation mediated by IL-1beta increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease. | Journal of neuroinflammation 20080101 |
Mitochondrial membrane potential in human neutrophils is maintained by complex III activity in the absence of supercomplex organisation. | PloS one 20080101 |
Proteomic modeling for HIV-1 infected microglia-astrocyte crosstalk. | PloS one 20080101 |
Ototoxic interaction of kanamycin and 3-nitropropionic acid. | Acta oto-laryngologica 20080101 |
PhoP: a missing piece in the intricate puzzle of Mycobacterium tuberculosis virulence. | PloS one 20080101 |
Protective efficiacy of taurine against pulmonary edema progression: experimental study. | Journal of cardiothoracic surgery 20080101 |
Prolonged pretreatment with carvedilol prevents 3-nitropropionic acid-induced behavioral alterations and oxidative stress in rats. | Pharmacological reports : PR 20080101 |
Reaction of chromium(III) with 3,4-dihydroxybenzoic acid: kinetics and mechanism in weak acidic aqueous solutions. | Bioinorganic chemistry and applications 20080101 |
Inflammatory and neurochemical changes associated with 3-nitropropionic Acid neurotoxicity. | Toxicology mechanisms and methods 20080101 |
Citicoline is not protective in experimental models of Huntington's disease. | Neurobiology of aging 20071201 |
Catecholamine exocytosis is diminished in R6/2 Huntington's disease model mice. | Journal of neurochemistry 20071201 |
Neurotoxic effects of repetitive inhibition of oxidative phosphorylation in young adults surfacing with deficits of spatial learning in old age. | The journals of gerontology. Series A, Biological sciences and medical sciences 20071201 |
Cannabinoids in health and disease. | Dialogues in clinical neuroscience 20071201 |
IGF-1 exacerbates the neurotoxicity of the mitochondrial inhibitor 3NP in rats. | Neuroscience letters 20071002 |
Memantine reduces neuronal dysfunctions triggered by in vitro ischemia and 3-nitropropionic acid. | Experimental neurology 20071001 |
Commonly used tropical medicinal plants exhibit distinct in vitro antioxidant activities against hepatotoxins in rat liver. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20070801 |
Mitochondrial respiratory inhibition and oxidative stress elevate beta-secretase (BACE1) proteins and activity in vivo in the rat retina. | Experimental brain research 20070801 |
The role of mitochondria in protection of the heart by preconditioning. | Biochimica et biophysica acta 20070801 |
Cannabidiol reduced the striatal atrophy caused 3-nitropropionic acid in vivo by mechanisms independent of the activation of cannabinoid, vanilloid TRPV1 and adenosine A2A receptors. | The European journal of neuroscience 20070801 |
Co-localization and functional cross-talk between A1 and P2Y1 purine receptors in rat hippocampus. | The European journal of neuroscience 20070801 |
Unbiased gene expression analysis implicates the huntingtin polyglutamine tract in extra-mitochondrial energy metabolism. | PLoS genetics 20070801 |
Changes in opioid receptor proteins during mitochondrial impairment in differentiated SK-N-SH cells. | Neuroscience letters 20070718 |
Annonacin, a natural mitochondrial complex I inhibitor, causes tau pathology in cultured neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20070718 |
Creatine treatment promotes differentiation of GABA-ergic neuronal precursors in cultured fetal rat spinal cord. | Journal of neuroscience research 20070701 |
Mesenchymal stem cell transplantation accelerates hearing recovery through the repair of injured cochlear fibrocytes. | The American journal of pathology 20070701 |
3-Nitropropionic acid activates calpain/cdk5 pathway in rat striatum. | Neuroscience letters 20070621 |
Exacerbation of excitotoxic neuronal death induced during mitochondrial inhibition in vivo: relation to energy imbalance or ATP depletion? | Neuroscience 20070608 |
Ubiquitin-proteasome system alterations in a striatal cell model of Huntington's disease. | Journal of neuroscience research 20070601 |
Manganese targets m-aconitase and activates iron regulatory protein 2 in AF5 GABAergic cells. | Journal of neuroscience research 20070601 |
Cyclooxygenase inhibition attenuates 3-nitropropionic acid-induced neurotoxicity in rats: possible antioxidant mechanisms. | Fundamental & clinical pharmacology 20070601 |
Mutant SOD1G93A in bone marrow-derived cells exacerbates 3-nitropropionic acid induced striatal damage in mice. | Neuroscience letters 20070517 |
Neurturin gene therapy improves motor function and prevents death of striatal neurons in a 3-nitropropionic acid rat model of Huntington's disease. | Neurobiology of disease 20070501 |
Effect of testosterone on oxidative stress and cell damage induced by 3-nitropropionic acid in striatum of ovariectomized rats. | Life sciences 20070306 |
Gender- and region-specific expression of insulin receptor protein in mouse brain: effect of mild inhibition of oxidative phosphorylation. | Journal of neural transmission (Vienna, Austria : 1996) 20070301 |
Cerebellar granule neurons are more vulnerable to transient transport-mediated glutamate release than to glutamate uptake blockade. correlation with excitatory amino acids levels. | Neurochemical research 20070301 |
Effects of 3-nitropropionic acid administration on memory and hippocampal lipid peroxidation in sleep-deprived mice. | Progress in neuro-psychopharmacology & biological psychiatry 20070130 |
Pharmacological MRI of stem cell transplants in the 3-nitropropionic acid-damaged striatum. | Neuroscience 20070105 |
Transglutaminase 2 ablation leads to defective function of mitochondrial respiratory complex I affecting neuronal vulnerability in experimental models of extrapyramidal disorders. | Journal of neurochemistry 20070101 |
Mitochondrial toxins and neurodegenerative diseases. | Frontiers in bioscience : a journal and virtual library 20070101 |
Integrative hypothesis for Huntington's disease: a brief review of experimental evidence. | Physiological research 20070101 |
Evidence of ROS generation by mitochondria in cells with impaired electron transport chain and mitochondrial DNA damage. | Mitochondrion 20070101 |
Proteasome activator enhances survival of Huntington's disease neuronal model cells. | PloS one 20070101 |
Possible neuroprotective mechanisms of curcumin in attenuating 3-nitropropionic acid-induced neurotoxicity. | Methods and findings in experimental and clinical pharmacology 20070101 |
Sequence variation in human succinate dehydrogenase genes: evidence for long-term balancing selection on SDHA. | BMC biology 20070101 |
Corticolimbic expression of TRPC4 and TRPC5 channels in the rodent brain. | PloS one 20070101 |
Hyperglycemia enhances the inhibitory effect of mitochondrial toxins and D,L-homocysteine on the brain production of kynurenic acid. | Pharmacological reports : PR 20070101 |
Early energy deficit in Huntington disease: identification of a plasma biomarker traceable during disease progression. | PloS one 20070101 |
Identification of gene targets against dormant phase Mycobacterium tuberculosis infections. | BMC infectious diseases 20070101 |
The responses of HT22 cells to the blockade of mitochondrial complexes and potential protective effect of selenium supplementation. | International journal of biological sciences 20070101 |
Animal models of Huntington's disease. | ILAR journal 20070101 |
The functional genome of CA1 and CA3 neurons under native conditions and in response to ischemia. | BMC genomics 20070101 |
Developmental stage of oligodendrocytes determines their response to activated microglia in vitro. | Journal of neuroinflammation 20070101 |
Polyphasic taxonomy of Aspergillus section Candidi based on molecular, morphological and physiological data. | Studies in mycology 20070101 |
MEK inhibition exacerbates ischemic calcium imbalance and neuronal cell death in rat cortical cultures. | European journal of pharmacology 20061228 |
Co-regulation of dopamine D1 receptor and uncoupling protein-2 expression in 3-nitropropionic acid-induced neurotoxicity: neuroprotective role of L-carnitine. | Neuroscience letters 20061213 |
Deficits of glutamate transmission in the striatum of toxic and genetic models of Huntington's disease. | Neuroscience letters 20061213 |
NR2B-containing NMDA receptors promote the neurotoxic effects of 3-nitropropionic acid but not of rotenone in the striatum. | Experimental neurology 20061201 |
Acute administration of 3-nitropropionic acid, a reactive oxygen species generator, boosts ethanol-induced locomotor stimulation. New support for the role of brain catalase in the behavioural effects of ethanol. | Neuropharmacology 20061201 |
Oral uridine pro-drug PN401 is neuroprotective in the R6/2 and N171-82Q mouse models of Huntington's disease. | Neurobiology of disease 20061201 |
Memantine reduces striatal cell death with decreasing calpain level in 3-nitropropionic model of Huntington's disease. | Brain research 20061106 |
D-beta-hydroxybutyrate protects dopaminergic SH-SY5Y cells in a rotenone model of Parkinson's disease. | Journal of neuroscience research 20061101 |
Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration. | Cell metabolism 20061101 |
Adenosine A2A receptors in bone marrow-derived cells but not in forebrain neurons are important contributors to 3-nitropropionic acid-induced striatal damage as revealed by cell-type-selective inactivation. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20061101 |
Infant mice with glutaric acidaemia type I have increased vulnerability to 3-nitropropionic acid toxicity. | Journal of inherited metabolic disease 20061001 |
Localization of superoxide anion production to mitochondrial electron transport chain in 3-NPA-treated cells. | Mitochondrion 20061001 |
Involvement of nitric oxide in 3-nitropropionic acid-induced striatal toxicity in rats. | Brain research 20060907 |
Increased 'vigilance' of antioxidant mechanisms in neural stem cells potentiates their capability to resist oxidative stress. | Stem cells (Dayton, Ohio) 20060901 |
S-Allylcysteine prevents the rat from 3-nitropropionic acid-induced hyperactivity, early markers of oxidative stress and mitochondrial dysfunction. | Neuroscience research 20060901 |
Effect of transcranial magnetic stimulation on oxidative stress induced by 3-nitropropionic acid in cortical synaptosomes. | Neuroscience research 20060901 |
Effect of resveratrol on 3-nitropropionic acid-induced biochemical and behavioural changes: possible neuroprotective mechanisms. | Behavioural pharmacology 20060901 |
Differential effects of impaired mitochondrial energy production on the function of mu and delta opioid receptors in neuronal SK-N-SH cells. | Neuroscience letters 20060814 |
Effects of L-carnitine pretreatment in methamphetamine and 3-nitropropionic acid-induced neurotoxicity. | Annals of the New York Academy of Sciences 20060801 |
The stamp of ancestry: roots of behavioral and neuronal impairment in adulthood. | Experimental neurology 20060701 |
Analysis of the regulation, expression, and localisation of the isocitrate lyase from Aspergillus fumigatus, a potential target for antifungal drug development. | Fungal genetics and biology : FG & B 20060701 |
Mitochondrial inhibition prior to oxygen-withdrawal facilitates the occurrence of hypoxia-induced spreading depression in rat hippocampal slices. | Journal of neurophysiology 20060701 |
Ischemic tolerance in chemical preconditioning: possible role of astrocytic glutamine synthetase buffering glutamate-mediated neurotoxicity. | Journal of neuroscience research 20060701 |
Therapeutic activity of C5a receptor antagonists in a rat model of neurodegeneration. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060701 |
Sp1 is up-regulated in cellular and transgenic models of Huntington disease, and its reduction is neuroprotective. | The Journal of biological chemistry 20060616 |
Longevity in mice: is stress resistance a common factor? | Age (Dordrecht, Netherlands) 20060601 |
Caspase-dependent and -independent cell death induced by 3-nitropropionic acid in rat cortical neurons. | Journal of cellular biochemistry 20060501 |
The role of peroxynitrite in chemical preconditioning with 3-nitropropionic acid in rat hearts. | Cardiovascular research 20060501 |
Transcranial magnetic stimulation attenuates cell loss and oxidative damage in the striatum induced in the 3-nitropropionic model of Huntington's disease. | Journal of neurochemistry 20060501 |
Brain mitochondrial defects amplify intracellular [Ca2+] rise and neurodegeneration but not Ca2+ entry during NMDA receptor activation. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060501 |
Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
Neuroprotective properties of memantine in different in vitro and in vivo models of excitotoxicity. | The European journal of neuroscience 20060501 |
Plastic and behavioral abnormalities in experimental Huntington's disease: a crucial role for cholinergic interneurons. | Neurobiology of disease 20060401 |
17 beta-Estradiol may affect vulnerability of striatum in a 3-nitropropionic acid-induced experimental model of Huntington's disease in ovariectomized rats. | Neurochemistry international 20060401 |
Endotoxin preconditioning protects neurones from in vitro ischemia: role of endogenous IL-1beta and TNF-alpha. | Journal of neuroimmunology 20060401 |
Cystamine and cysteamine prevent 3-NP-induced mitochondrial depolarization of Huntington's disease knock-in striatal cells. | The European journal of neuroscience 20060401 |
[The research of the pathogen responsible for Pleurocybella porrigens related encephalopathy: investigation of 3-nitropropionic acid hypothesis]. | No to shinkei = Brain and nerve 20060401 |
Lactate dehydrogenase activity is inhibited by methylmalonate in vitro. | Neurochemical research 20060401 |
3-nitropropionic acid is a suicide inhibitor of mitochondrial respiration that, upon oxidation by complex II, forms a covalent adduct with a catalytic base arginine in the active site of the enzyme. | The Journal of biological chemistry 20060303 |
Mice lacking alpha-synuclein are resistant to mitochondrial toxins. | Neurobiology of disease 20060301 |
Metabolic insights into the hepatoprotective role of N-acetylcysteine in mouse liver. | Hepatology (Baltimore, Md.) 20060301 |
Neuronal and astrocytic shuttle mechanisms for cytosolic-mitochondrial transfer of reducing equivalents: current evidence and pharmacological tools. | Biochemical pharmacology 20060214 |
Mechanisms of hypoxic tolerance in presymptomatic APP23 transgenic mice. | Mechanisms of ageing and development 20060201 |
[Aristolochic acid nephropathy and acute encephalopathy related to Pleurocybella porrigens (Sugihiratake)]. | Nihon rinsho. Japanese journal of clinical medicine 20060201 |
Protective effect of S-allylcysteine on 3-nitropropionic acid-induced lipid peroxidation and mitochondrial dysfunction in rat brain synaptosomes. | Brain research bulletin 20060130 |
Alterations in the cortical and peripheral somatosensory evoked activity of rats treated with 3-nitropropionic acid. | Toxicology letters 20060125 |
UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the progression of different motor-related disorders. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20060101 |
Effect of coenzyme Q10 and vitamin E on brain energy metabolism in the animal model of Huntington's disease. | Neurochemistry international 20060101 |
Growth inhibition by nitrocompounds of selected uric acid-utilizing microorganisms isolated from poultry manure. | Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20060101 |
The carcinogenic potential of tacrolimus ointment beyond immune suppression: a hypothesis creating case report. | BMC cancer 20060101 |
Preservation of striatal tissue and behavioral function after neural stem cell transplantation in a rat model of Huntington's disease. | Neuroscience 20060101 |
[Hairy root induction and plant regeneration of crownvetch (Coronilla varia L.) transformed by Agrobacterium rhizogenes]. | Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20060101 |
Delayed postconditionig initiates additive mechanism necessary for survival of selectively vulnerable neurons after transient ischemia in rat brain. | Cellular and molecular neurobiology 20060101 |
Melatonin in Alzheimer's disease and other neurodegenerative disorders. | Behavioral and brain functions : BBF 20060101 |
The changes in endogenous antioxidant enzyme activity after postconditioning. | Cellular and molecular neurobiology 20060101 |
Hypoxic vasoconstriction of partial muscular intra-acinar pulmonary arteries in murine precision cut lung slices. | Respiratory research 20060101 |
Kinetic modeling of tricarboxylic acid cycle and glyoxylate bypass in Mycobacterium tuberculosis, and its application to assessment of drug targets. | Theoretical biology & medical modelling 20060101 |
3-Nitropropionic acid toxicity in hippocampus: protection through N-methyl-D-aspartate receptor antagonism. | Hippocampus 20060101 |
Involvement of calpain activation in neurodegenerative processes. | CNS drug reviews 20060101 |
Genetic analysis of the GRIK2 modifier effect in Huntington's disease. | BMC neuroscience 20060101 |
Mitochondrial oxidative damage in aging and Alzheimer's disease: implications for mitochondrially targeted antioxidant therapeutics. | Journal of biomedicine & biotechnology 20060101 |
Estrogen protects neuronal cells from amyloid beta-induced apoptosis via regulation of mitochondrial proteins and function. | BMC neuroscience 20060101 |
Cerebral ischemic tolerance induced by 3-nitropropionic acid is associated with increased expression of erythropoietin in rats. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20060101 |
The acute effects of 3-nitropropionic acid on the behavior and spontaneous cortical electrical activity of rats. | Acta neurobiologiae experimentalis 20060101 |
Wild-type huntingtin ameliorates striatal neuronal atrophy but does not prevent other abnormalities in the YAC128 mouse model of Huntington disease. | BMC neuroscience 20060101 |
Inhibition of mitochondrial complex II affects dopamine metabolism and decreases its uptake into striatal synaptosomes. | Folia neuropathologica 20060101 |
Mitochondrial toxins in Basal Ganglia disorders: from animal models to therapeutic strategies. | Current neuropharmacology 20060101 |
Mitochondrial cyclic AMP response element-binding protein (CREB) mediates mitochondrial gene expression and neuronal survival. | The Journal of biological chemistry 20051209 |
3-Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease. | Journal of neurochemistry 20051201 |
Effects of 3-nitropropionic acid in rats: general toxicity and functional neurotoxicity. | Arhiv za higijenu rada i toksikologiju 20051201 |
Neuroprotective effect of taurine in 3-nitropropionic acid-induced experimental animal model of Huntington's disease phenotype. | Pharmacology, biochemistry, and behavior 20051101 |
Evidence for a role of second pathophysiological stress in prevention of delayed neuronal death in the hippocampal CA1 region. | Neurochemical research 20051101 |
Effects of mitochondrial toxins on the brain amino acid concentrations. | Neurochemical research 20051101 |
Behavioral alterations in Lewis rats following two-day continuous 3-nitropropionic acid administration. | Neurotoxicity research 20051101 |
Differential effects of sublethal ischemia and chemical preconditioning with 3-nitropropionic acid on protein expression in gerbil hippocampus. | Life sciences 20051021 |
The histaminergic signaling system exerts a neuroprotective role against neurodegenerative-induced processes in the hamster. | The Journal of pharmacology and experimental therapeutics 20051001 |
Neuroprotective effect of zVAD against the neurotoxin 3-nitropropionic acid involves inhibition of calpain. | Neuropharmacology 20051001 |
Effects of creatine treatment on survival and differentiation of GABA-ergic neurons in cultured striatal tissue. | Journal of neurochemistry 20051001 |
[Animal models of parkinsonism]. | Revue neurologique 20051001 |
Neuroprotective effect of nicotine against 3-nitropropionic acid (3-NP)-induced experimental Huntington's disease in rats. | Brain research bulletin 20050930 |
A potential role for beta- and gamma-crystallins in the vascular remodeling of the eye. | Developmental dynamics : an official publication of the American Association of Anatomists 20050901 |
Depressant effect of mitochondrial respiratory complex inhibitors on proteasome inhibitor-induced mitochondrial dysfunction and cell death in PC12 cells. | Neurochemical research 20050901 |
Mitochondrial regulation of insulin production in rat pancreatic islets. | Diabetologia 20050801 |
Celastrol protects against MPTP- and 3-nitropropionic acid-induced neurotoxicity. | Journal of neurochemistry 20050801 |
Identification of rat hippocampal mRNAs altered by the mitochondrial toxicant, 3-NPA. | Annals of the New York Academy of Sciences 20050801 |
L-carnitine and neuroprotection in the animal model of mitochondrial dysfunction. | Annals of the New York Academy of Sciences 20050801 |
Effects of metabolic modifiers such as carnitines, coenzyme Q10, and PUFAs against different forms of neurotoxic insults: metabolic inhibitors, MPTP, and methamphetamine. | Annals of the New York Academy of Sciences 20050801 |
Effects of ATP-sensitive potassium channel activators diazoxide and BMS-191095 on membrane potential and reactive oxygen species production in isolated piglet mitochondria. | Brain research bulletin 20050730 |
The critical threshold of 3-nitropropionic acid-induced ischemic tolerance in the rat. | Brain research 20050719 |
Arvanil, a hybrid endocannabinoid and vanilloid compound, behaves as an antihyperkinetic agent in a rat model of Huntington's disease. | Brain research 20050719 |
Crystal structure of mitochondrial respiratory membrane protein complex II. | Cell 20050701 |
Inducible neuronal expression of transgenic TGF-beta1 in vivo: dissection of short-term and long-term effects. | The European journal of neuroscience 20050701 |
3-Nitropropionic acid (3-NPA), a potent antimycobacterial agent from endophytic fungi: is 3-NPA in some plants produced by endophytes? | Journal of natural products 20050701 |
The differential JunB responses to inhibition of succinate dehydrogenase in rat hippocampus and liver. | Neuroscience letters 20050624 |
Altered distribution of striatal activity-dependent synaptic plasticity in the 3-nitropropionic acid model of Huntington's disease. | Brain research 20050621 |
Induction of the Nrf2-driven antioxidant response confers neuroprotection during mitochondrial stress in vivo. | The Journal of biological chemistry 20050617 |
Melatonin protects against neuronal damage induced by 3-nitropropionic acid in rat striatum. | Brain research 20050607 |
Treatment with dehydroepiandrosterone prevents oxidative stress induced by 3-nitropropionic acid in synaptosomes. | Pharmacology 20050601 |
Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence. | Nature medicine 20050601 |
Neuroprotection by adenosine in the brain: From A(1) receptor activation to A (2A) receptor blockade. | Purinergic signalling 20050601 |
The nature of the stimulus and of the fumarate binding site of the fumarate sensor DcuS of Escherichia coli. | The Journal of biological chemistry 20050527 |
Effects of riluzole on combined MPTP + 3-nitropropionic acid-induced mild to moderate striatonigral degeneration in mice. | Journal of neural transmission (Vienna, Austria : 1996) 20050501 |
Induction of hypoxia inducible factor-1 attenuates metabolic insults induced by 3-nitropropionic acid in rat C6 glioma cells. | Journal of neurochemistry 20050501 |
Protective effects of ginseng components in a rodent model of neurodegeneration. | Annals of neurology 20050501 |
Grafted neural stem cells shield the host environment from oxidative stress. | Annals of the New York Academy of Sciences 20050501 |
Functional neurotoxic effects in rats elicited by 3-nitropropionic acid in acute and subacute administration. | Environmental toxicology and pharmacology 20050501 |
Susceptibility to excitotoxic and metabolic striatal neurodegeneration in the mouse is genotype dependent. | Brain research 20050408 |
Regional selectivity of amyloid mRNA expression and neurotrophins on repetitive inhibition of oxidative phosphorylation. | Journal of neural transmission (Vienna, Austria : 1996) 20050401 |
Protective effects of ginseng saponins on 3-nitropropionic acid-induced striatal degeneration in rats. | Neuropharmacology 20050401 |
Toxicity and metabolism of the conjugates of 3-nitropropanol and 3-nitropropionic acid in forages poisonous to livestock. | Journal of agricultural and food chemistry 20050323 |
Oxidative stress in transgenic mice with oligodendroglial alpha-synuclein overexpression replicates the characteristic neuropathology of multiple system atrophy. | The American journal of pathology 20050301 |
Fluoro-Jade C results in ultra high resolution and contrast labeling of degenerating neurons. | Brain research 20050221 |
3-nitropropionic acid-induced hydrogen peroxide, mitochondrial DNA damage, and cell death are attenuated by Bcl-2 overexpression in PC12 cells. | Brain research. Molecular brain research 20050218 |
Proteomic analysis of oxidatively modified proteins induced by the mitochondrial toxin 3-nitropropionic acid in human astrocytes expressing the HIV protein tat. | Brain research. Molecular brain research 20050218 |
Minocycline in phenotypic models of Huntington's disease. | Neurobiology of disease 20050201 |
Acute effects of pulsed microwaves and 3-nitropropionic acid on neuronal ultrastructure in the rat caudate-putamen. | Bioelectromagnetics 20050201 |
Paradoxical increase in 3-nitropropionic acid neurotoxicity by alpha-phenyl-tert-butyl-nitrone, a spin-trapping agent. | Chang Gung medical journal 20050201 |
Scope and limitations of the nitro-Mannich reaction for the stereoselective synthesis of 1,2-diamines. | The Journal of organic chemistry 20050121 |
3-nitropropionic acid model of metabolic stress: assessment by magnetic resonance imaging. | Methods in molecular medicine 20050101 |
Adenosine A1 receptors and the anticonvulsant potential of drugs effective in the model of 3-nitropropionic acid-induced seizures in mice. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20050101 |
A novel azulenyl nitrone antioxidant protects against MPTP and 3-nitropropionic acid neurotoxicities. | Experimental neurology 20050101 |
Neurotrophic factor expression after focal brain ischemia preceded by different preconditioning strategies. | Cerebrovascular diseases (Basel, Switzerland) 20050101 |
Permanent threshold shift caused by acute cochlear mitochondrial dysfunction is primarily mediated by degeneration of the lateral wall of the cochlea. | Audiology & neuro-otology 20050101 |
Gait dynamics in mouse models of Parkinson's disease and Huntington's disease. | Journal of neuroengineering and rehabilitation 20050101 |
Overexpression of Bcl-xl protects septal neurons from prolonged hypoglycemia and from acute ischemia-like stress. | Neuroscience 20050101 |
Chemical preconditioning by 3-nitropropionic acid reduces ischemia-reperfusion injury in rat heart. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20050101 |
FK506 prevents mitochondrial-dependent apoptotic cell death induced by 3-nitropropionic acid in rat primary cortical cultures. | Neurobiology of disease 20041201 |
Nicotinic receptor modulation for neuroprotection and enhancement of functional recovery following brain injury or disease. | Annals of the New York Academy of Sciences 20041201 |
Effect of nicotine on 3-nitropropionic acid-induced oxidative stress in synaptosomes. | European journal of pharmacology 20041119 |
The mitochondrial toxin, 3-nitropropionic acid, induces extracellular Zn2+ accumulation in rat hippocampus slices. | Neuroscience letters 20041111 |
A novel systemically active caspase inhibitor attenuates the toxicities of MPTP, malonate, and 3NP in vivo. | Neurobiology of disease 20041101 |
Protective effect of melatonin on 3-nitropropionic acid-induced oxidative stress in synaptosomes in an animal model of Huntington's disease. | Journal of pineal research 20041101 |
Potential involvement of cannabinoid receptors in 3-nitropropionic acid toxicity in vivo. | Neuroreport 20041025 |
Creatine protects against 3-nitropropionic acid-induced cell death in murine corticostriatal slice cultures. | Brain research 20041022 |
Menadione reduces rotenone-induced cell death in cerebellar granule neurons. | Neuroreport 20041005 |
Influence of chemical and ischemic preconditioning on cytokine expression after focal brain ischemia. | Journal of neuroscience research 20041001 |
Increased Alix (apoptosis-linked gene-2 interacting protein X) immunoreactivity in the degenerating striatum of rats chronically treated by 3-nitropropionic acid. | Neuroscience letters 20040930 |
Neuroprotective effect of L-carnitine in the 3-nitropropionic acid (3-NPA)-evoked neurotoxicity in rats. | Neuroscience letters 20040902 |
Mitochondrial permeability transition in neuronal damage promoted by Ca2+ and respiratory chain complex II inhibition. | Journal of neurochemistry 20040901 |
Antioxidant effects of taurine, vitamin C, and vitamin E on oxidative damage in hippocampus caused by the administration of 3-nitropropionic acid in rats. | The International journal of neuroscience 20040901 |
Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane inhibit mitochondrial swelling, oxidative cell death, and reperfusion injury. | The Journal of biological chemistry 20040813 |
The c-Raf inhibitor GW5074 provides neuroprotection in vitro and in an animal model of neurodegeneration through a MEK-ERK and Akt-independent mechanism. | Journal of neurochemistry 20040801 |
Strain dependence of receptor regulation on chemical preconditioning in mice hippocampus. | Neuroscience letters 20040729 |
A novel animal model of acute cochlear mitochondrial dysfunction. | Neuroreport 20040719 |
Nitrification by plants that also fix nitrogen. | Nature 20040701 |
Altered oxidative stress response of the long-lived Snell dwarf mouse. | Biochemical and biophysical research communications 20040611 |
3-Nitropropionic acid-induced neurotoxicity--assessed by ultra high resolution positron emission tomography with comparison to magnetic resonance spectroscopy. | Journal of neurochemistry 20040601 |
Proactive transplantation of human neural stem cells prevents degeneration of striatal neurons in a rat model of Huntington disease. | Neurobiology of disease 20040601 |
Deleterious effects of minocycline in animal models of Parkinson's disease and Huntington's disease. | The European journal of neuroscience 20040601 |
Protective effects of S-nitrosoglutathione against neurotoxicity of 3-nitropropionic acid in rat. | Neuroscience letters 20040527 |
Induction of corticostriatal LTP by 3-nitropropionic acid requires the activation of mGluR1/PKC pathway. | Neuropharmacology 20040501 |
Striatal cells from mutant huntingtin knock-in mice are selectively vulnerable to mitochondrial complex II inhibitor-induced cell death through a non-apoptotic pathway. | Human molecular genetics 20040401 |
Production of toxic metabolites in Aspergillus niger, Aspergillus oryzae, and Trichoderma reesei: justification of mycotoxin testing in food grade enzyme preparations derived from the three fungi. | Regulatory toxicology and pharmacology : RTP 20040401 |
Experimental basis for the putative role of GluR6/kainate glutamate receptor subunit in Huntington's disease natural history. | Neurobiology of disease 20040401 |
Effect of glucocorticoids on 3-nitropropionic acid-induced oxidative stress in synaptosomes. | European journal of pharmacology 20040319 |
Inhibition of mitochondrial complex II alters striatal expression of genes involved in glutamatergic and dopaminergic signaling: possible implications for Huntington's disease. | Neurobiology of disease 20040301 |
Mice deficient in dihydrolipoamide dehydrogenase show increased vulnerability to MPTP, malonate and 3-nitropropionic acid neurotoxicity. | Journal of neurochemistry 20040301 |
Mitochondrial calcium, oxidative stress and apoptosis in a neurodegenerative disease model induced by 3-nitropropionic acid. | Journal of neurochemistry 20040301 |
Genetic and pharmacological inactivation of the adenosine A2A receptor attenuates 3-nitropropionic acid-induced striatal damage. | Journal of neurochemistry 20040201 |
Death of cortical and striatal neurons induced by mitochondrial defect involves differential molecular mechanisms. | Neurobiology of disease 20040201 |
Magnetic resonance imaging and spectroscopy in assessing 3-nitropropionic acid-induced brain lesions: an animal model of Huntington's disease. | Progress in neurobiology 20040201 |
Chronic intoxication with 3-nitropropionic acid in rats induces the loss of striatal dopamine terminals without affecting nigral cell viability. | Neuroscience letters 20040116 |
MPTP potentiates 3-nitropropionic acid-induced striatal damage in mice: reference to striatonigral degeneration. | Experimental neurology 20040101 |
Neuronal vulnerability following inhibition of mitochondrial complex II: a possible ionic mechanism for Huntington's disease. | Molecular and cellular neurosciences 20040101 |
Sertoli cell grafts for Huntington's disease. An opinion. | Neurotoxicity research 20040101 |
Chronic memantine does not block 3-nitropropionic acid-delayed ischaemic tolerance in rat hippocampal slices ex vivo. | Neurotoxicity research 20040101 |
Involvement of apoptosis in 3-nitropropionic acid-induced ischemic tolerance to transient focal cerebral ischemia in rats. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20040101 |
Differential depression of spinal synaptic transmission in vitro by different hypoxic insults. | Indian journal of experimental biology 20040101 |
Pharmacological preconditioning in global cerebral ischemia. | Acta neurochirurgica. Supplement 20040101 |
Hypoxic increase in nitric oxide generation of rat sensory neurons requires activation of mitochondrial complex II and voltage-gated calcium channels. | Neuroscience 20040101 |
Inhibition of caspase-3 activation and apoptosis is involved in 3-nitropropionic acid-induced ischemic tolerance to transient focal cerebral ischemia in rats. | Journal of molecular neuroscience : MN 20040101 |
Neurotoxins and neurotoxic species implicated in neurodegeneration. | Neurotoxicity research 20040101 |
Oral uridine pro-drug PN401 decreases neurodegeneration, behavioral impairment, weight loss and mortality in the 3-nitropropionic acid mitochondrial toxin model of Huntington's disease. | Brain research 20031219 |
Glutamate uptake inhibitor L-trans-pyrrolidine 2,4-dicarboxylate becomes neurotoxic in the presence of subthreshold concentrations of mitochondrial toxin 3-nitropropionate: involvement of mitochondrial reducing activity and ATP production. | Journal of neuroscience research 20031215 |
Effects of mitochondrial inhibitors and uncouplers on hypoxic vasoconstriction in rabbit lungs. | American journal of respiratory cell and molecular biology 20031201 |
Bcl-2 prevents loss of cell viability and caspase activation induced by 3-nitropropionic acid in GT1-7 cells. | Annals of the New York Academy of Sciences 20031201 |
Diazoxide induces delayed pre-conditioning in cultured rat cortical neurons. | Journal of neurochemistry 20031101 |
In vivo calpain/caspase cross-talk during 3-nitropropionic acid-induced striatal degeneration: implication of a calpain-mediated cleavage of active caspase-3. | The Journal of biological chemistry 20031031 |
3-Nitropropionic acid increases frataxin expression in human lymphoblasts and in transgenic rat PC12 cells. | Neuroscience letters 20031030 |
Histone deacetylase inhibition by sodium butyrate chemotherapy ameliorates the neurodegenerative phenotype in Huntington's disease mice. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20031015 |
Neuroprotection and neuronal dysfunction upon repetitive inhibition of oxidative phosphorylation. | Experimental neurology 20031001 |
Neurodegeneration in striatum induced by the mitochondrial toxin 3-nitropropionic acid: role of matrix metalloproteinase-9 in early blood-brain barrier disruption? | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030924 |
Chemical preconditioning prevents paradoxical increase in glutamate release during ischemia by activating ATP-dependent potassium channels in gerbil hippocampus. | Experimental neurology 20030901 |
Type I glutaric aciduria, part 2: a model of acute striatal necrosis. | American journal of medical genetics. Part C, Seminars in medical genetics 20030815 |
Neuropathological and behavioral changes induced by various treatment paradigms with MPTP and 3-nitropropionic acid in mice: towards a model of striatonigral degeneration (multiple system atrophy). | Acta neuropathologica 20030801 |
Differential responsiveness of rat striatal nerve endings to the mitochondrial toxin 3-nitropropionic acid: implications for Huntington's disease. | The European journal of neuroscience 20030801 |
Influence of cytosolic and mitochondrial Ca2+, ATP, mitochondrial membrane potential, and calpain activity on the mechanism of neuron death induced by 3-nitropropionic acid. | Neurochemistry international 20030701 |
Alpha-synuclein protects naive but not dbcAMP-treated dopaminergic cell types from 1-methyl-4-phenylpyridinium toxicity. | Journal of neurochemistry 20030701 |
GFAP knockout mice have increased levels of GDNF that protect striatal neurons from metabolic and excitotoxic insults. | The Journal of comparative neurology 20030630 |
Calpain is a major cell death effector in selective striatal degeneration induced in vivo by 3-nitropropionate: implications for Huntington's disease. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030615 |
A dual role of adenosine A2A receptors in 3-nitropropionic acid-induced striatal lesions: implications for the neuroprotective potential of A2A antagonists. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030615 |
The effect on motor cortical neuronal development of focal lesions to the sub-cortical white matter in the neonatal rat: a model for periventricular leukomalacia. | International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20030601 |
Structural and functional neuroprotection in a rat model of Huntington's disease by viral gene transfer of GDNF. | Experimental neurology 20030601 |
1,3-Dinitrobenzene inhibits mitochondrial complex II in rat and mouse brainstem and cortical astrocytes. | Neurotoxicology 20030601 |
Age-associated changes in SAPK/JNK and p38 MAPK signaling in response to the generation of ROS by 3-nitropropionic acid. | Mechanisms of ageing and development 20030601 |
Calpain facilitates the neuron death induced by 3-nitropropionic acid and contributes to the necrotic morphology. | Journal of neuropathology and experimental neurology 20030601 |
Essential role of complex II of the respiratory chain in hypoxia-induced ROS generation in the pulmonary vasculature. | American journal of physiology. Lung cellular and molecular physiology 20030501 |
Sp1 and Sp3 are oxidative stress-inducible, antideath transcription factors in cortical neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030501 |
Possible mechanism for the neuroprotective effects of L-carnitine on methamphetamine-evoked neurotoxicity. | Annals of the New York Academy of Sciences 20030501 |
Neuroprotective effects of L-carnitine in induced mitochondrial dysfunction. | Annals of the New York Academy of Sciences 20030501 |
3-nitropropionic acid inhibition of succinate dehydrogenase (complex II) activity in cultured Chinese hamster ovary cells: antagonism by L-carnitine. | Annals of the New York Academy of Sciences 20030501 |
Opening of mitochondrial ATP-sensitive potassium channels is a trigger of 3-nitropropionic acid-induced tolerance to transient focal cerebral ischemia in rats. | Stroke 20030401 |
Quantitative on-line monitoring of hippocampus glucose and lactate metabolism in organotypic cultures using biosensor technology. | Journal of neurochemistry 20030401 |
Neuroprotective effects of (+/-)-huprine Y on in vitro and in vivo models of excitoxicity damage. | Experimental neurology 20030401 |
Knockout of p75NTR does not alter the viability of striatal neurons following a metabolic or excitotoxic injury. | Journal of molecular neuroscience : MN 20030401 |
Differential regulation of 5' splice variants of the glutamate transporter EAAT2 in an in vivo model of chemical hypoxia induced by 3-nitropropionic acid. | Journal of neuroscience research 20030315 |
Specific progressive cAMP reduction implicates energy deficit in presymptomatic Huntington's disease knock-in mice. | Human molecular genetics 20030301 |
Compounds acting at the endocannabinoid and/or endovanilloid systems reduce hyperkinesia in a rat model of Huntington's disease. | Journal of neurochemistry 20030301 |
Microglial activation and cell death induced by the mitochondrial toxin 3-nitropropionic acid: in vitro and in vivo studies. | Neurobiology of disease 20030301 |
Mitochondrial complex inhibitors preferentially damage substantia nigra dopamine neurons in rat brain slices. | Experimental neurology 20030101 |
Polycyclic phenols, estrogens and neuroprotection: a proposed mitochondrial mechanism. | Experimental gerontology 20030101 |
Homocysteine-induced brain lipid peroxidation: effects of NMDA receptor blockade, antioxidant treatment, and nitric oxide synthase inhibition. | Neurotoxicity research 20030101 |
FK506 attenuates 1-methyl-4-phenylpyridinium- and 3-nitropropionic acid-evoked inhibition of kynurenic acid synthesis in rat cortical slices. | Acta neurobiologiae experimentalis 20030101 |
Mitochondrial complex II is essential for hypoxia-induced ROS generation and vasoconstriction in the pulmonary vasculature. | Advances in experimental medicine and biology 20030101 |
Mitochondrial complex I inhibition produces selective damage to hippocampal subfield CA1 in organotypic slice cultures. | Neurotoxicity research 20030101 |
Effects of Sertoli cell transplants in a 3-nitropropionic acid model of early Huntington's disease: a preliminary study. | Neurotoxicity research 20030101 |
Dystonia is predictive of subsequent altered dopaminergic responsiveness in a chronic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine+3-nitropropionic acid model of striatonigral degeneration in monkeys. | Neuroscience letters 20021219 |
Estrogen blocks 3-nitropropionic acid-induced Ca2+i increase and cell damage in cultured rat cerebral endothelial cells. | Brain research 20021122 |
Calcium-dependent cleavage of endogenous wild-type huntingtin in primary cortical neurons. | The Journal of biological chemistry 20021018 |
The adenosine A1 receptor agonist adenosine amine congener exerts a neuroprotective effect against the development of striatal lesions and motor impairments in the 3-nitropropionic acid model of neurotoxicity. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20021015 |
1-Methyl-4-phenylpyridinium and 3-nitropropionic acid diminish cortical synthesis of kynurenic acid via interference with kynurenine aminotransferases in rats. | Neuroscience letters 20020913 |
Analysis of mitochondrial free radical generation in animal models of neuronal disease. | Free radical biology & medicine 20020901 |
The effect of aging on p38 signaling pathway activity in the mouse liver and in response to ROS generated by 3-nitropropionic acid. | Mechanisms of ageing and development 20020901 |
Effect of 3-nitropropionic acid on kynurenine aminotransferase in the rat brain. | Experimental neurology 20020901 |
3-Nitropropionic acid induces cell death and mitochondrial dysfunction in rat corticostriatal slice cultures. | Neuroscience letters 20020823 |
Neuroprotection by hypoxic preconditioning requires sequential activation of vascular endothelial growth factor receptor and Akt. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020801 |
Striatal and cortical neurochemical changes induced by chronic metabolic compromise in the 3-nitropropionic model of Huntington's disease. | Neurobiology of disease 20020801 |
Decreased TCA cycle rate in the rat brain after acute 3-NP treatment measured by in vivo 1H-[13C] NMR spectroscopy. | Journal of neurochemistry 20020801 |
Reduction of Alamar Blue, a novel redox indicator, is dependent on both the glycolytic and oxidative metabolism of glucose in rat cultured neurons. | Neuroscience letters 20020705 |
The differential vulnerability of striatal projection neurons in 3-nitropropionic acid-treated rats does not match that typical of adult-onset Huntington's disease. | Experimental neurology 20020701 |
beta-Amyloid neurotoxicity is exacerbated during glycolysis inhibition and mitochondrial impairment in the rat hippocampus in vivo and in isolated nerve terminals: implications for Alzheimer's disease. | Experimental neurology 20020701 |
3-Nitropropionic acid neurotoxicity in hippocampal slice cultures: developmental and regional vulnerability and dependency on glucose. | Experimental neurology 20020701 |
Mice overexpressing 70-kDa heat shock protein show increased resistance to malonate and 3-nitropropionic acid. | Experimental neurology 20020701 |
Involvement of superoxide in excitotoxicity and DNA fragmentation in striatal vulnerability in mice after treatment with the mitochondrial toxin, 3-nitropropionic acid. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020701 |
Corticostriatopallidal neuroprotection by adenovirus-mediated ciliary neurotrophic factor gene transfer in a rat model of progressive striatal degeneration. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020601 |
Dopamine transporter knock-out mice are hypersensitive to 3-nitropropionic acid-induced striatal damage. | The European journal of neuroscience 20020601 |
A method to assay glyoxylate cycle inhibitors for antifungals. | The Journal of antibiotics 20020601 |
3-nitropropionic acid-induced changes in bilayer fluidity in synaptosomal membranes: implications for Huntington's disease. | Neurochemical research 20020601 |
Chemical preconditioning with 3-nitropropionic acid: lack of induction of neuronal tolerance in gerbil hippocampus subjected to transient forebrain ischemia. | Brain research bulletin 20020501 |
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
Mitochondrial toxin inhibition of [(3)H]dopamine uptake into rat striatal synaptosomes. | Biochemical pharmacology 20020415 |
Alleviation of motor hyperactivity and neurochemical deficits by endocannabinoid uptake inhibition in a rat model of Huntington's disease. | Synapse (New York, N.Y.) 20020401 |
Gender-dependent hypoxic tolerance mediated via gender-specific mechanisms. | Journal of neuroscience research 20020401 |
[Huntington disease]. | Nihon rinsho. Japanese journal of clinical medicine 20020401 |
Coenzyme Q10 as a possible treatment for neurodegenerative diseases. | Free radical research 20020401 |
Evaluation of 3-nitrotyrosine as a marker for 3-nitropropionic acid-induced oxidative stress in Lewis and Wistar rats and strain-specific whole brain spheroid cultures. | Brain research 20020322 |
Excitotoxic and metabolic damage to the rodent striatum: role of the P75 neurotrophin receptor and glial progenitors. | The Journal of comparative neurology 20020318 |
The mitochondrial toxin 3-nitropropionic acid induces striatal neurodegeneration via a c-Jun N-terminal kinase/c-Jun module. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020315 |
Modulation of apoptotic regulatory proteins and early activation of cytochrome C following systemic 3-nitropropionic acid administration. | Brain research bulletin 20020315 |
ATP-dependent potassium channel mediates neuroprotection by chemical preconditioning with 3-nitropropionic acid in gerbil hippocampus. | Neuroscience letters 20020301 |
Hypoxic tolerance induction in rat brain slices following 3-nitropropionic acid pretreatment as revealed by dynamic changes in glucose metabolism. | Neuroscience letters 20020215 |
Immediate-early gene response to methamphetamine, haloperidol, and quinolinic acid is not impaired in Huntington's disease transgenic mice. | Journal of neuroscience research 20020201 |
The mitochondrial toxin 3-nitropropionic acid aggravates reserpine-induced oral dyskinesia in rats. | Progress in neuro-psychopharmacology & biological psychiatry 20020201 |
Partial ablations of the flocculus and ventral paraflocculus in monkeys cause linked deficits in smooth pursuit eye movements and adaptive modification of the VOR. | Journal of neurophysiology 20020201 |
Evaluation of neuronal cell death by laser scanning cytometry. | Brain research. Brain research protocols 20020201 |
A simple method to measure stride length as an index of nigrostriatal dysfunction in mice. | Journal of neuroscience methods 20020130 |
Behavioral and morphological comparison of two nonhuman primate models of Huntington's disease. | Neurosurgery 20020101 |
The mechanisms of neuronal death produced by mitochondrial toxin 3-nitropropionic acid: the roles of N-methyl-D-aspartate glutamate receptors and mitochondrial calcium overload. | Neuroscience 20020101 |
Acute and chronic alterations in calcium homeostasis in 3-nitropropionic acid-treated human NT2-N neurons. | Neuroscience 20020101 |
Impaired hypoxic tolerance and altered protein binding of NADH in presymptomatic APP23 transgenic mice. | Neuroscience 20020101 |
Subacute systemic 3-nitropropionic acid intoxication induces a distinct motor disorder in adult C57Bl/6 mice: behavioural and histopathological characterisation. | Neuroscience 20020101 |
Increased neuronal hypoxic tolerance induced by repetitive chemical hypoxia. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20020101 |
Neuroprotective role of L-carnitine in the 3-nitropropionic acid induced neurotoxicity. | Toxicology letters 20011215 |
Elucidation of the quantitative significance of pyruvate carboxylation in cultured cerebellar neurons and astrocytes. | Journal of neuroscience research 20011201 |
Excretion of miserotoxin and detoxification of the aglycone by grasshoppers (Orthoptera: Acrididae). | Phytochemistry 20011101 |
Perseverative behavior underlying attentional set-shifting deficits in rats chronically treated with the neurotoxin 3-nitropropionic acid. | Experimental neurology 20011101 |
Inhibition of glutamate uptake into synaptic vesicles from rat brain by 3-nitropropionic acid in vitro. | Experimental neurology 20011101 |
Concentrations of different sterols in the striatum and serum of 3-nitropropionic acid-treated Wistar and Lewis rats. | Neurochemical research 20011101 |
A bile acid protects against motor and cognitive deficits and reduces striatal degeneration in the 3-nitropropionic acid model of Huntington's disease. | Experimental neurology 20011001 |
Mitochondrial toxin 3-nitropropionic acid induces cardiac and neurotoxicity differentially in mice. | The American journal of pathology 20011001 |
Fluoro-Jade and silver methods: application to the neuropathology of scrapie, a transmissible spongiform encephalopathy. | Brain research. Brain research protocols 20011001 |
Phospholipid fatty acids and neurotoxicity in human neuroblastoma SH-SY5Y cells. | Neuroscience letters 20010831 |
In vivo hydroxyl radical formation after quinolinic acid infusion into rat corpus striatum. | Neuroreport 20010828 |
Taurine increases rat survival and reduces striatal damage caused by 3-nitropropionic acid. | The International journal of neuroscience 20010801 |
Changes in endocannabinoid transmission in the basal ganglia in a rat model of Huntington's disease. | Neuroreport 20010720 |
Inhibition of mitochondrial complex II induces a long-term potentiation of NMDA-mediated synaptic excitation in the striatum requiring endogenous dopamine. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20010715 |
Topological analysis of striatal lesions induced by 3-nitropropionic acid in the Lewis rat. | Neuroreport 20010613 |
Protective effect of adenosine receptor agonists in a new model of epilepsy--seizures evoked by mitochondrial toxin, 3-nitropropionic acid, in mice. | Neuroscience letters 20010608 |
Effect of L-carnitine pretreatment on 3-nitropropionic acid-induced inhibition of rat brain succinate dehydrogenase activity. | Annals of the New York Academy of Sciences 20010601 |
Biomarkers of 3-nitropropionic acid (3-NPA)-induced mitochondrial dysfunction as indicators of neuroprotection. | Annals of the New York Academy of Sciences 20010601 |
Strategies for neuroprotection against L-trans-2,4-pyrrolidine dicarboxylate-induced neuronal damage during energy impairment in vitro. | Journal of neuroscience research 20010515 |
Manganese toxicity is associated with mitochondrial dysfunction and DNA fragmentation in rat primary striatal neurons. | Brain research bulletin 20010515 |
Chemical preconditioning with 3-nitropropionic acid in hearts: role of mitochondrial K(ATP) channel. | American journal of physiology. Heart and circulatory physiology 20010501 |
Estradiol protects against ATP depletion, mitochondrial membrane potential decline and the generation of reactive oxygen species induced by 3-nitroproprionic acid in SK-N-SH human neuroblastoma cells. | Journal of neurochemistry 20010501 |
Transgenic ALS mice show increased vulnerability to the mitochondrial toxins MPTP and 3-nitropropionic acid. | Experimental neurology 20010401 |
N-Acetylaspartate, a marker of both cellular dysfunction and neuronal loss: its relevance to studies of acute brain injury. | Journal of neurochemistry 20010401 |
Glucose deprivation and chemical hypoxia: neuroprotection by P2 receptor antagonists. | Neurochemistry international 20010301 |
[Neuroprotective effect of a neurotoxin, 3-nitropropionic acid, against hypoxic damage to the gerbil hippocampus: neuroprotection after the onset of hypoxic depolarization]. | No to shinkei = Brain and nerve 20010301 |
Contamination of food with mycotoxins and human health. | Arhiv za higijenu rada i toksikologiju 20010301 |
White matter damage following systemic injection of the mitochondrial inhibitor 3-nitropropionic acid in rat. | Brain research 20010223 |
Chemical preconditioning in mice is not mediated by upregulation of nitric oxide synthase isoforms. | Neuroscience letters 20010216 |
'Chemical preconditioning' by 3-nitropropionate reduces ischemia-reperfusion injury in cardiac-arrested rat lungs. | Transplantation 20010215 |
Orphenadrine prevents 3-nitropropionic acid-induced neurotoxicity in vitro and in vivo. | British journal of pharmacology 20010201 |
Oxidative stress and neuronal DNA fragmentation mediate age-dependent vulnerability to the mitochondrial toxin, 3-nitropropionic acid, in the mouse striatum. | Neurobiology of disease 20010201 |
The mitochondrial toxin 3-nitropropionic acid induces differential expression patterns of apoptosis-related markers in rat striatum. | Neuropathology and applied neurobiology 20010201 |
Expression of brain-derived neurotrophic factor in cortical neurons is regulated by striatal target area. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20010101 |
Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP. | Experimental neurology 20010101 |
On the mechanisms of neuroprotection by creatine and phosphocreatine. | Journal of neurochemistry 20010101 |
No functional effects of embryonic neuronal grafts on motor deficits in a 3-nitropropionic acid rat model of advanced striatonigral degeneration (multiple system atrophy). | Neuroscience 20010101 |
Behavioural correlates of striatal glial fibrillary acidic protein in the 3-nitropropionic acid rat model: disturbed walking pattern and spatial orientation. | Neuroscience 20010101 |
Neurotoxicity of glutamate uptake inhibition in vivo: correlation with succinate dehydrogenase activity and prevention by energy substrates. | Neuroscience 20010101 |
Neuronal ectopic expression of tyrosine hydroxylase in the mouse striatum by combined administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 3-nitropropionic acid. | Neuroscience 20010101 |
Neurotoxicology of the brain barrier system: new implications. | Journal of toxicology. Clinical toxicology 20010101 |
Effect of adenosine receptor agonists on neurodegenerative and convulsive activity of mitochondrial toxin, 3-nitropropionic acid. | Polish journal of pharmacology 20010101 |
Brain tolerance and preconditioning. | Polish journal of pharmacology 20010101 |
Tauroursodeoxycholic acid partially prevents apoptosis induced by 3-nitropropionic acid: evidence for a mitochondrial pathway independent of the permeability transition. | Journal of neurochemistry 20001201 |
Neuroprotective role for the p50 subunit of NF-kappaB in an experimental model of Huntington's disease. | Journal of molecular neuroscience : MN 20000801 |
Efficacy of 101 antimicrobials and other agents on the development of Cryptosporidium parvum in vitro. | Annals of tropical medicine and parasitology 19961201 |
[Studies on the potentiation of the antibiotics contained in Prednobiotad]. | DTW. Deutsche tierarztliche Wochenschrift 19760105 |
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