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CAS No: 50-44-2 Catalog No: AG0038PH MDL No:MFCD18074515
Title | Journal |
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Thiopurine-induced toxicity is associated with dysfunction variant of the human molybdenum cofactor sulfurase gene (xanthinuria type II). | Toxicology and applied pharmacology 20180620 |
Why are most phospholipidosis inducers also hERG blockers? | Archives of toxicology 20171201 |
Risk factors for thiopurine-induced myelosuppression and infections in inflammatory bowel disease patients with a normal TPMT genotype. | Alimentary pharmacology & therapeutics 20171101 |
Evaluating the Role of Multidrug Resistance Protein 3 (MDR3) Inhibition in Predicting Drug-Induced Liver Injury Using 125 Pharmaceuticals. | Chemical research in toxicology 20170515 |
Nurr1 and PPARγ protect PC12 cells against MPP(+) toxicity: involvement of selective genes, anti-inflammatory, ROS generation, and antimitochondrial impairment. | Molecular and cellular biochemistry 20160901 |
HLA-DQA1-HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants. | Nature genetics 20141001 |
A common missense variant in NUDT15 confers susceptibility to thiopurine-induced leukopenia. | Nature genetics 20140901 |
Genetic polymorphisms in candidate genes predict increased toxicity with methotrexate therapy in Lebanese children with acute lymphoblastic leukemia. | Pharmacogenetics and genomics 20140801 |
Identification of potent Yes1 kinase inhibitors using a library screening approach. | Bioorganic & medicinal chemistry letters 20130801 |
Microarray analysis of 6-mercaptopurine-induced-toxicity-related genes and microRNAs in the rat placenta. | The Journal of toxicological sciences 20130201 |
Fabrication of biodegradable micelles with reduction-triggered release of 6-mercaptopurine profile based on disulfide-linked graft copolymer conjugate. | Colloids and surfaces. B, Biointerfaces 20121201 |
Antibiotic susceptibility profile of Mycobacterium avium subspecies hominissuis is altered in low-iron conditions. | The Journal of antimicrobial chemotherapy 20121201 |
S-allyl derivatives of 6-mercaptopurine are highly potent drugs against human B-CLL through synergism between 6-mercaptopurine and allicin. | Leukemia research 20121201 |
The investigation of the binding of 6-mercaptopurine to site I on human serum albumin. | The protein journal 20121201 |
6-[(1-naphthylmethyl)sulfanyl]-9H-purine induces G2/M phase arrest and apoptosis in human hepatocellular carcinoma HepG2 cells. | European journal of pharmacology 20121115 |
Asparaginase-associated myelosuppression and effects on dosing of other chemotherapeutic agents in childhood acute lymphoblastic leukemia. | Pediatric blood & cancer 20121101 |
Pregnancy outcome after paternal exposure to azathioprine/6-mercaptopurine. | Reproductive toxicology (Elmsford, N.Y.) 20121101 |
PACSIN2 polymorphism influences TPMT activity and mercaptopurine-related gastrointestinal toxicity. | Human molecular genetics 20121101 |
Preparation, characterization and in vitro release study of a glutathione-dependent polymeric prodrug Cis-3-(9H-purin-6-ylthio)-acrylic acid-graft-carboxymethyl chitosan. | International journal of pharmaceutics 20121015 |
A step toward more accurate dosing for mercaptopurine in childhood acute lymphoblastic leukemia. | Journal of clinical pharmacology 20121001 |
Long-term MRI-guided combined anti-TNF-α and thiopurine therapy for Crohn's perianal fistulas. | Inflammatory bowel diseases 20121001 |
Increased small intestinal permeability in ulcerative colitis: rather genetic than environmental and a risk factor for extensive disease? | Inflammatory bowel diseases 20121001 |
Optimising outcome on thiopurines in inflammatory bowel disease by co-prescription of allopurinol. | Journal of Crohn's & colitis 20121001 |
Current relevance of pharmacogenetics in immunomodulation treatment for Crohn's disease. | Journal of gastroenterology and hepatology 20121001 |
Treatment of young patients with Philadelphia chromosome-positive acute lymphoblastic leukaemia using increased dose of imatinib and deintensified chemotherapy before allogeneic stem cell transplantation. | British journal of haematology 20121001 |
Purine anti-metabolite attenuates nuclear factor κB and related pro-inflammatory cytokines in experimental vasospasm. | Acta neurochirurgica 20121001 |
Determination of thiols by capillary micellar electrokinetic chromatography with laser induced fluorescence detection using 1,3,5,7-tetramethyl-8-phenyl-(4-iodoacetamido) difluoroboradiaza-s-indacene as labeling reagent. | Journal of separation science 20121001 |
Establishment of thiopurine S-methyltransferase gene knockdown in jurkat T-lymphocytes: an in vitro model of TPMT polymorphism. | Therapeutic drug monitoring 20121001 |
Propionyl-L-carnitine hydrochloride for treatment of mild to moderate colonic inflammatory bowel diseases. | World journal of gastroenterology 20120928 |
Oxidation-mediated DNA cross-linking contributes to the toxicity of 6-thioguanine in human cells. | Cancer research 20120915 |
Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis. | The Cochrane database of systematic reviews 20120912 |
Prevention and synergistic control of Ph(+) ALL by a DNA vaccine and 6-mercaptopurine. | Vaccine 20120907 |
Comparative cost-effectiveness of strategies to prevent postoperative clinical recurrence of Crohn's disease. | Inflammatory bowel diseases 20120901 |
Incidence of and impact of medications on colectomy in newly diagnosed ulcerative colitis in the era of biologics. | Inflammatory bowel diseases 20120901 |
Nine years interval between first and second bone marrow transplantations and subsequent long-term survival--a case of acute myeloid leukemia with MLL-AF6 fusion gene. | Annals of hematology 20120901 |
Pharmacogenetic determinants of mercaptopurine disposition in children with acute lymphoblastic leukemia. | European journal of clinical pharmacology 20120901 |
Secondary Epstein-Barr virus associated lymphoproliferative disorder developing in a patient with angioimmunoblastic T cell lymphoma on vorinostat. | American journal of hematology 20120901 |
Split-dose administration of thiopurine drugs: a novel and effective strategy for managing preferential 6-MMP metabolism. | Alimentary pharmacology & therapeutics 20120901 |
Immunosuppression in patients with Crohn's disease and neoplasia: an ongoing clinical dilemma. | Diseases of the colon and rectum 20120901 |
An audit of influenza vaccination status in adults with inflammatory bowel disease. | Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20120901 |
All-trans-retinoic acid, idarubicin, and IV arsenic trioxide as initial therapy in acute promyelocytic leukemia (APML4). | Blood 20120823 |
Nutritional therapy versus 6-mercaptopurine as maintenance therapy in patients with Crohn's disease. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20120801 |
Risk of melanoma and nonmelanoma skin cancer among patients with inflammatory bowel disease. | Gastroenterology 20120801 |
The potential influence of 5-aminosalicylic acid on the induction of myelotoxicity during thiopurine therapy in inflammatory bowel disease patients. | European journal of gastroenterology & hepatology 20120801 |
Withaferin A-related steroids from Withania aristata exhibit potent antiproliferative activity by inducing apoptosis in human tumor cells. | European journal of medicinal chemistry 20120801 |
Pharmacogenomic applications in oncology. | Journal of pharmacy practice 20120801 |
[Thiopurine S-methyltransferase gene sequence analysis of ALL children severely intolerant to 6-mercaptopurine]. | Zhongguo shi yan xue ye xue za zhi 20120801 |
Label-free, non-derivatization CRET detection platform for 6-mercaptopurine based on the distance-dependent optical properties of gold nanoparticles. | Chemistry (Weinheim an der Bergstrasse, Germany) 20120702 |
Prediction of outcome by early bone marrow response in childhood acute lymphoblastic leukemia treated in the ALL-BFM 95 trial: differential effects in precursor B-cell and T-cell leukemia. | Haematologica 20120701 |
Genotyping should be considered the primary choice for pre-treatment evaluation of thiopurine methyltransferase function. | Journal of Crohn's & colitis 20120701 |
Prevention of postoperative recurrence of Crohn's disease. | Journal of Crohn's & colitis 20120701 |
Therapeutic drug monitoring of thiopurine metabolites in adult thiopurine tolerant IBD patients on maintenance therapy. | Journal of Crohn's & colitis 20120701 |
Combination therapy with arsenic trioxide, all-trans retinoic acid, and chemotherapy in acute promyelocytic leukemia patients with various relapse risks. | Leukemia research 20120701 |
Intracellular disposition of methotrexate in acute lymphoblastic leukemia in children. | Current drug metabolism 20120701 |
Identifying youth nonadherence in clinical settings: data-based recommendations for children and adolescents with inflammatory bowel disease. | Inflammatory bowel diseases 20120701 |
Letter: TPMT - not all that glitters is gold. | Alimentary pharmacology & therapeutics 20120701 |
Genetic variants of thiopurine and folate metabolic pathways determine 6-MP-mediated hematological toxicity in childhood ALL. | Pharmacogenomics 20120701 |
Nonadherence to oral mercaptopurine and risk of relapse in Hispanic and non-Hispanic white children with acute lymphoblastic leukemia: a report from the children's oncology group. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120610 |
Haematopoietic SCT in severe autoimmune diseases: updated guidelines of the European Group for Blood and Marrow Transplantation. | Bone marrow transplantation 20120601 |
Cryptosporidium gastroenteritis in Egyptian children with acute lymphoblastic leukemia: magnitude of the problem. | Infection 20120601 |
Thiopurine treatment in inflammatory bowel disease: response predictors, safety, and withdrawal in follow-up. | Journal of Crohn's & colitis 20120601 |
Optimizing immunomodulators and anti-TNF agents in the therapy of Crohn disease. | Gastroenterology clinics of North America 20120601 |
Infliximab exerts no direct hepatotoxic effect on HepG2 cells in vitro. | Digestive diseases and sciences 20120601 |
Langerhans cell histiocytosis presenting as a multi-system disorder in an infant. | International journal of dermatology 20120601 |
Intermittent granulocyte and monocyte apheresis versus mercaptopurine for maintaining remission of ulcerative colitis: a pilot study. | Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20120601 |
A histopathologic pattern of centrilobular hepatocyte injury suggests 6-mercaptopurine-induced hepatotoxicity in patients with inflammatory bowel disease. | Archives of pathology & laboratory medicine 20120601 |
Ulcerative colitis. | BMJ (Clinical research ed.) 20120510 |
Comparison of clinical characteristics and management of inflammatory bowel disease in Hong Kong versus Melbourne. | Journal of gastroenterology and hepatology 20120501 |
Influence of age, sex, and haplotypes of thiopurine methyltransferase (TPMT) gene on 6- mercaptopurine toxicity in children with acute lymphoblastic leukemia. | European journal of clinical pharmacology 20120501 |
Factors associated with nonadherence to thiopurines in adolescent and adult patients with inflammatory bowel disease. | Journal of pediatric gastroenterology and nutrition 20120501 |
The activity of the inosine triphosphate pyrophosphatase affects toxicity of 6-mercaptopurine during maintenance therapy for acute lymphoblastic leukemia in Japanese children. | Leukemia research 20120501 |
Progressive primary sclerosing cholangitis requiring liver transplantation is associated with reduced need for colectomy in patients with ulcerative colitis. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20120501 |
Initiating azathioprine for Crohn's disease. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20120501 |
Confocal Raman microspectroscopic study of folate receptor-targeted delivery of 6-mercaptopurine-embedded gold nanoparticles in a single cell. | Journal of biomedical materials research. Part A 20120501 |
Central nervous system lesions due to juvenile myelomonocytic leukemia progressed in a boy undergoing first line chemotherapy. | International journal of hematology 20120501 |
High TPMT enzyme activity does not explain drug resistance due to preferential 6-methylmercaptopurine production in patients on thiopurine treatment. | Alimentary pharmacology & therapeutics 20120501 |
Azathioprine in the treatment of autoimmune blistering diseases. | Immunology and allergy clinics of North America 20120501 |
[Treatment of inflammatory bowel disease in intensive care medicine]. | Deutsche medizinische Wochenschrift (1946) 20120501 |
A child with pulmonary and liver Langerhans'-cell histiocytosis. | Chinese medical journal 20120501 |
[The effect of early immunosuppressive therapy on the rate of resections performed in patients with Chron's disease, in Veszprém county, Hungary, a population-based cohort study]. | Orvosi hetilap 20120408 |
Tracking multiplex drugs and their dynamics in living cells using the label-free surface-enhanced Raman scattering technique. | Molecular pharmaceutics 20120402 |
Multivariate models to detect genomic signatures for a class of drugs: application to thiopurines pharmacogenomics. | The pharmacogenomics journal 20120401 |
Polymorphism of ITPA 94C>A and risk of adverse effects among patients with acute lymphoblastic leukaemia treated with 6-mercaptopurine. | Journal of clinical pharmacy and therapeutics 20120401 |
Unexpected pancytopenia following treatment of acute lymphoblastic leukemia. | American journal of hematology 20120401 |
Autoimmune cholecystitis. | Journal of pediatric gastroenterology and nutrition 20120401 |
Epistatic interactions between thiopurine methyltransferase (TPMT) and inosine triphosphate pyrophosphatase (ITPA) variations determine 6-mercaptopurine toxicity in Indian children with acute lymphoblastic leukemia. | European journal of clinical pharmacology 20120401 |
NOD2 polymorphism predicts response to treatment in Crohn's disease--first steps to a personalized therapy. | Digestive diseases and sciences 20120401 |
How informative is a negative finding in a small pharmacogenetic study? | The pharmacogenomics journal 20120401 |
Has there been a change in the natural history of Crohn's disease? Surgical rates and medical management in a population-based inception cohort from Western Hungary between 1977-2009. | The American journal of gastroenterology 20120401 |
Mutational analysis of human glutathione transferase A2-2 identifies structural elements supporting high activity with the prodrug azathioprine. | Protein engineering, design & selection : PEDS 20120401 |
Endoscopic ultrasound for perianal Crohn's disease: disease and fistula characteristics, and impact on therapy. | Journal of Crohn's & colitis 20120401 |
Validation of a genotyping method for analysis of TPMT polymorphisms. | Clinical therapeutics 20120401 |
Effect of an anti-thyroid drug, 2,8-Dimercapto-6-hydroxy purine on reproduction in male rats. | Pakistan journal of pharmaceutical sciences 20120401 |
Langerhans cell histiocytosis with perianal localization. | Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia 20120401 |
Epigallocatechin-3-gallate Inhibits LPS-Induced NF-κB and MAPK Signaling Pathways in Bone Marrow-Derived Macrophages. | Gut and liver 20120401 |
Real-time monitoring of glutathione-triggered thiopurine anticancer drug release in live cells investigated by surface-enhanced Raman scattering. | Analytical chemistry 20120306 |
Mercaptopurine-induced hypersensitivity febrile reaction in patient with acute promyelocytic leukemia. | Leukemia & lymphoma 20120301 |
Managing chronic disease in Ireland: hospital admission rates and clinical outcomes in a large ulcerative colitis population. | Irish journal of medical science 20120301 |
Evaluation of drugs with specific organ toxicities in organ-specific cell lines. | Toxicological sciences : an official journal of the Society of Toxicology 20120301 |
Review article: a decision-making algorithm for the management of pregnancy in the inflammatory bowel disease patient. | Alimentary pharmacology & therapeutics 20120301 |
CDA deficiency as a possible culprit for life-threatening toxicities after cytarabine plus 6-mercaptopurine therapy: pharmacogenetic investigations. | Pharmacogenomics 20120301 |
Aberrant cyclization affords a C-6 modified cyclic adenosine 5'-diphosphoribose analogue with biological activity in Jurkat T cells. | Journal of medicinal chemistry 20120223 |
Simultaneous quantification of eleven thiopurine nucleotides by liquid chromatography-tandem mass spectrometry. | Analytical chemistry 20120207 |
Normal response to vaccines in inflammatory bowel disease patients treated with thiopurines. | Inflammatory bowel diseases 20120201 |
Thiopurines prevent advanced colorectal neoplasia in patients with inflammatory bowel disease. | Gut 20120201 |
Use of thiopurines in the treatment of inflammatory bowel disease is associated with an increased risk of non-melanoma skin cancer in an at-risk population: a cohort study. | Journal of gastroenterology and hepatology 20120201 |
Results of the APML3 trial incorporating all-trans-retinoic acid and idarubicin in both induction and consolidation as initial therapy for patients with acute promyelocytic leukemia. | Haematologica 20120201 |
Overexpression of P-glycoprotein induces acquired resistance to imatinib in chronic myelogenous leukemia cells. | Chinese journal of cancer 20120201 |
Why thiopurine metabolites are relevant. | Alimentary pharmacology & therapeutics 20120201 |
6-Mercaptopurine transport in human lymphocytes: correlation with drug-induced cytotoxicity. | Journal of digestive diseases 20120201 |
Risk of non-melanoma skin cancer with thiopurine use in inflammatory bowel disease. | Journal of gastroenterology and hepatology 20120201 |
Hepatotoxicity associated with 6-methyl mercaptopurine formation during azathioprine and 6-mercaptopurine therapy does not occur on the short-term during 6-thioguanine therapy in IBD treatment. | Journal of Crohn's & colitis 20120201 |
A randomized comparison of modified intermediate-dose Ara-C versus high-dose ara-c in post-remission therapy for acute myeloid leukemia. | Anticancer research 20120201 |
6-mercaptopurine influences TPMT gene transcription in a TPMT gene promoter variable number of tandem repeats-dependent manner. | Pharmacogenomics 20120201 |
[Two cases of thiopurine-induced acute pancreatitis in inflammatory bowel disease]. | Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20120201 |
[Guidelines for the management of Crohn's disease]. | The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20120201 |
Co-existence of Crohn's disease, sarcoidosis and malignant lymphomas. | JRSM short reports 20120201 |
Role of base-excision repair in the treatment of childhood acute lymphoblastic leukaemia with 6-mercaptopurine and high doses of methotrexate. | Mutation research 20120124 |
Liquid chromatography-tandem mass spectrometry quantification of 6-thioguanine in DNA using endogenous guanine as internal standard. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120115 |
Pneumocystis jiroveci pneumonia prophylaxis during maintenance therapy influences methotrexate/6-mercaptopurine dosing but not event-free survival for childhood acute lymphoblastic leukemia. | European journal of haematology 20120101 |
UVA photosensitization of thiopurines and skin cancer in organ transplant recipients. | Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20120101 |
Inherited prothrombotic risk factors in Turkish children with acute lymphoblastic leukemia: significance of concomitant genetic mutation. | Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20120101 |
Evaluation of a group-based behavioral intervention to promote adherence in adolescents with inflammatory bowel disease. | European journal of gastroenterology & hepatology 20120101 |
Review article: the benefits of pharmacogenetics for improving thiopurine therapy in inflammatory bowel disease. | Alimentary pharmacology & therapeutics 20120101 |
Outcome predictors for thiopurine maintenance therapy in patients with Crohn's disease. | Digestive diseases and sciences 20120101 |
General insufficiency of the classical CDC-based crossmatch to detect donor-specific anti-HLA antibodies leading to invalid results under recipients' medical treatment or underlying diseases. | Histology and histopathology 20120101 |
Two brothers with skewed thiopurine metabolism in ulcerative colitis treated successfully with allopurinol and mercaptopurine dose reduction. | Digestive diseases and sciences 20120101 |
Intrauterine exposure to thiopurines. | Reproductive toxicology (Elmsford, N.Y.) 20120101 |
Eosinophilic esophagitis for the otolaryngologist. | International journal of otolaryngology 20120101 |
Impact of complex NOTCH1 mutations on survival in paediatric T-cell leukaemia. | BMC cancer 20120101 |
Vitamins A & D inhibit the growth of mycobacteria in radiometric culture. | PloS one 20120101 |
Erythrocyte inosine triphosphatase activity is decreased in HIV-seropositive individuals. | PloS one 20120101 |
Towards curative therapy in burkitt lymphoma: the role of early african studies in demonstrating the value of combination therapy and CNS prophylaxis. | Advances in hematology 20120101 |
Polo Like Kinase 2 Tumour Suppressor and cancer biomarker: new perspectives on drug sensitivity/resistance in ovarian cancer. | Oncotarget 20120101 |
[A case of primary colon amyloidosis presenting as hematochezia]. | The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20120101 |
Trends in qualifying biomarkers in drug safety. Consensus of the 2011 meeting of the spanish society of clinical pharmacology. | Frontiers in pharmacology 20120101 |
Infection from an exfoliating primary tooth in a child with severe neutropenia: a case report. | Pediatric dentistry 20120101 |
Neuromyelitis optica: an antibody-mediated disorder of the central nervous system. | Neurology research international 20120101 |
Hyperbaric oxygen treatment for inflammatory bowel disease: a systematic review and analysis. | Medical gas research 20120101 |
Population analysis of pharmacogenetic polymorphisms related to acute lymphoblastic leukemia drug treatment. | Disease markers 20120101 |
[Lenalidomide induced therapeutic response in a patient with aggressive multi-system Langerhans cell histiocytosis resistant to 2-chloro-deoxyadenosine and early relapsing after high-dose BEAM chemotherapy with autologous peripheral blood stem cell transplantation]. | Vnitrni lekarstvi 20120101 |
Combination therapy with adalimumab plus intensive granulocyte and monocyte adsorptive apheresis induced clinical remission in a Crohn's disease patient with the loss of response to scheduled adalimumab maintenance therapy: a case report. | Internal medicine (Tokyo, Japan) 20120101 |
Developmental changes of aldehyde oxidase activity and protein expression in human liver cytosol. | Drug metabolism and pharmacokinetics 20120101 |
Multisystem Langerhans cell histiocytosis in adult. | Indian journal of dermatology 20120101 |
Liver disorders in inflammatory bowel disease. | Gastroenterology research and practice 20120101 |
Cryopreservation of ovarian tissue in pediatric patients. | Obstetrics and gynecology international 20120101 |
Treatment of autoimmune pancreatitis with the anecdotes of the first report. | International journal of rheumatology 20120101 |
A Case of Atypical Delayed and Prolonged Hematologic Toxicity With Azacitidine in Chronic Myelomonocytic Leukemia (CMML) and Review of Literature. | Mediterranean journal of hematology and infectious diseases 20120101 |
Linking proteins to signaling pathways for experiment design and evaluation. | PloS one 20120101 |
Right-wing politicians prefer the emotional left. | PloS one 20120101 |
Characterization of 6-mercaptopurine binding site on human alpha1-acid glycoprotein (orosomucoid) using molecular docking. | Acta poloniae pharmaceutica 20120101 |
Targeted delivery of nanomedicines. | ISRN pharmacology 20120101 |
Thiopurine S-methyltransferase phenotype-genotype correlation in children with acute lymphoblastic leukemia. | Acta poloniae pharmaceutica 20120101 |
Study of drug metabolism by xanthine oxidase. | International journal of molecular sciences 20120101 |
Unilateral hemiparesis with thoracic epidural in an adolescent. | Case reports in anesthesiology 20120101 |
Therapeutic effect of captopril, pentoxifylline, and cordyceps sinensis in pre-hepatic portal hypertensive rats. | Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20120101 |
A case of relapsing-remitting neuroborreliosis? Challenges in the differential diagnosis of recurrent myelitis. | Case reports in neurology 20120101 |
Acute eosinophilic ascites in a middle-aged man. | Case reports in gastrointestinal medicine 20120101 |
Diffuse large B-cell lymphoma in an adolescent female presenting with Epstein-Barr virus-driven hemophagocytic lymphohistiocytosis: a case report. | Journal of medical case reports 20120101 |
Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism. | PloS one 20120101 |
Protein-losing enteropathy in ulcerative colitis. | Case reports in gastroenterology 20120101 |
6-Mercaptopurine-induced histopathological changes and xanthine oxidase expression in rat placenta. | The Journal of toxicological sciences 20120101 |
A validated HPLC method for the monitoring of thiopurine metabolites in whole blood in paediatric patients with inflammatory bowel disease. | International journal of immunopathology and pharmacology 20120101 |
All-Trans Retinoic Acid-Induced Pseudotumor Cerebri during Induction Therapy for Acute Promyelocytic Leukemia: A Case Report and Literature Review. | Case reports in oncological medicine 20120101 |
Analyzing gene expression profile in K562 cells exposed to sodium valproate using microarray combined with the connectivity map database. | Journal of biomedicine & biotechnology 20120101 |
Collagenous colitis and spondylarthropathy. | Case reports in medicine 20120101 |
Toxicity of azathioprine: why and when? analysis of the prevalence of polymorphism in Joinville, SC, Brazil. | Arquivos de gastroenterologia 20120101 |
Pharmacogenetic analysis of pediatric patients with acute lymphoblastic leukemia: a possible association between survival rate and ITPA polymorphism. | PloS one 20120101 |
First-line therapies in inflammatory bowel disease. | Digestion 20120101 |
Therapy of steroid-resistant inflammatory bowel disease. | Digestion 20120101 |
A systematic review and meta-analysis of the effects of infliximab on the rate of colectomy and post-operative complications in patients with inflammatory bowel disease. | Archives of medical science : AMS 20111231 |
Pharmacogenetics, cost of genotyping, and guidelines for individualizing therapy with mercaptopurine in pediatric acute lymphoblastic leukemia. | Pediatric blood & cancer 20111215 |
Diagnosis and management of Crohn's disease. | American family physician 20111215 |
[FAQs in chronic inflammatory bowel diseases. This way your patient stays in remission]. | MMW Fortschritte der Medizin 20111208 |
Use of thiopurine testing in the management of inflammatory bowel diseases in clinical practice: a worldwide survey of experts. | Inflammatory bowel diseases 20111201 |
Acute respiratory failure in 3 children with juvenile myelomonocytic leukemia. | Journal of pediatric hematology/oncology 20111201 |
Early use of immunosuppressives or TNF antagonists for the treatment of Crohn's disease: time for a change. | Gut 20111201 |
Role of thiopurine and anti-TNF therapy in lymphoma in inflammatory bowel disease. | The American journal of gastroenterology 20111201 |
Mucosal healing for predicting clinical outcome in patients with ulcerative colitis using thiopurines in monotherapy. | European journal of internal medicine 20111201 |
Allopurinol enhances the activity of hypoxanthine-guanine phosphoribosyltransferase in inflammatory bowel disease patients during low-dose thiopurine therapy: preliminary data of an ongoing series. | Nucleosides, nucleotides & nucleic acids 20111201 |
Birth outcome in women with ulcerative colitis and Crohn's disease, and pharmacoepidemiological aspects of anti-inflammatory drug therapy. | Danish medical bulletin 20111201 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
6-Fluoro-2-(4-meth-oxy-phen-yl)imidazo[2,1-b][1,3]benzothia-zole. | Acta crystallographica. Section E, Structure reports online 20111201 |
Treatment of myasthenia gravis based on its immunopathogenesis. | Journal of clinical neurology (Seoul, Korea) 20111201 |
Synthesis of pro-prodrugs L-lysine based for 5-aminosalicylic acid and 6-mercaptopurine colon specific release. | International journal of pharmaceutics 20111128 |
Surgical resection in Crohn's disease: is immunosuppressive medication associated with higher postoperative infection rates? | Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20111101 |
Thiopurine methyltransferase polymorphisms and mercaptopurine tolerance in Turkish children with acute lymphoblastic leukemia. | Cancer chemotherapy and pharmacology 20111101 |
Randomised placebo-controlled trial of rituximab (anti-CD20) in active ulcerative colitis. | Gut 20111101 |
Association of Crohn's disease, thiopurines, and primary epstein-barr virus infection with hemophagocytic lymphohistiocytosis. | The Journal of pediatrics 20111101 |
Rheumatoid arthritis and pregnancy: evolution of disease activity and pathophysiological considerations for drug use. | Rheumatology (Oxford, England) 20111101 |
The transfer of 6-mercaptopurine in the dually perfused human placenta. | Reproductive toxicology (Elmsford, N.Y.) 20111101 |
Evaluating the use of metabolite measurement in children receiving treatment with a thiopurine. | Alimentary pharmacology & therapeutics 20111101 |
Hepatosplenic T-cell lymphoma in patients receiving TNF-α inhibitor therapy: expanding the groups at risk. | European journal of gastroenterology & hepatology 20111101 |
Thiopurine metabolites and TPMT activity measurement in inflammatory bowel disease. | Alimentary pharmacology & therapeutics 20111101 |
6-Mercaptopurine: an effective drug in the management of advanced cutaneous T-cell lymphoma. | Cutis 20111101 |
Optimizing 6-mercaptopurine and azathioprine therapy in the management of inflammatory bowel disease. | World journal of gastroenterology 20111007 |
Thiopurine S-methyltransferase (TPMT) polymorphisms in children with acute lymphoblastic leukemia, and the need for reduction or cessation of 6-mercaptopurine doses during maintenance therapy: the Polish multicenter analysis. | Pediatric blood & cancer 20111001 |
Augmented therapy improves outcome for pediatric high risk acute lymphocytic leukemia: results of Children's Oncology Group trial P9906. | Pediatric blood & cancer 20111001 |
Individually tailored treatment of medication nonadherence. | Journal of pediatric gastroenterology and nutrition 20111001 |
A cross-sectional investigation of chronic exposure to microcystin in relationship to childhood liver damage in the Three Gorges Reservoir Region, China. | Environmental health perspectives 20111001 |
Update on the management of ulcerative colitis. | Current gastroenterology reports 20111001 |
Mesenchymal stromal cell function is not affected by drugs used in the treatment of inflammatory bowel disease. | Cytotherapy 20111001 |
Individualized toxicity-titrated 6-mercaptopurine increments during high-dose methotrexate consolidation treatment of lower risk childhood acute lymphoblastic leukaemia. A Nordic Society of Paediatric Haematology and Oncology (NOPHO) pilot study. | British journal of haematology 20111001 |
Thiopurine metabolite measurement - not for everyone. | Alimentary pharmacology & therapeutics 20111001 |
Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cells. | Nature medicine 20111001 |
Diagnosis and treatment of fistulising Crohn's disease. | Danish medical bulletin 20111001 |
Splenic littoral cell hemangioendothelioma in a patient with Crohn's disease previously treated with immunomodulators and anti-TNF agents: a rare tumor linked to deep immunosuppression. | The American journal of gastroenterology 20111001 |
Nucleobase transport by human equilibrative nucleoside transporter 1 (hENT1). | The Journal of biological chemistry 20110916 |
Thiopurine immunomodulators in ulcerative colitis: moving forward with current evidence. | Current drug targets 20110901 |
6-Mercaptopurine transport by equilibrative nucleoside transporters in conditionally immortalized rat syncytiotrophoblast cell lines TR-TBTs. | Journal of pharmaceutical sciences 20110901 |
Thiopurine methyl-transferase activity and azathioprine metabolite concentrations do not predict clinical outcome in thiopurine-treated inflammatory bowel disease patients. | Alimentary pharmacology & therapeutics 20110901 |
3-Aryl-2-[1H-benzotriazol-1-yl]acrylonitriles: a novel class of potent tubulin inhibitors. | European journal of medicinal chemistry 20110901 |
Risk of malignant lymphoma in patients with inflammatory bowel diseases: a Dutch nationwide study. | Inflammatory bowel diseases 20110901 |
Autoimmune neuromuscular disorders. | Current neuropharmacology 20110901 |
Neuropsychiatric systemic lupus erythematosus. | Current neuropharmacology 20110901 |
Toxicities of immunosuppressive treatment of autoimmune neurologic diseases. | Current neuropharmacology 20110901 |
Food-borne bacteremic illnesses in febrile neutropenic children. | Hematology reports 20110831 |
[Stratification therapy in patients with acute promyelocytic leukemia after a complete remission by all-trans retinoic acid]. | Zhonghua yi xue za zhi 20110830 |
ABCC multidrug transporters in childhood neuroblastoma: clinical and biological effects independent of cytotoxic drug efflux. | Journal of the National Cancer Institute 20110817 |
Efficient DNA interstrand crosslinking by 6-thioguanine and UVA radiation. | DNA repair 20110815 |
Minimally invasive surface-enhanced Raman scattering detection with depth profiles based on a surface-enhanced Raman scattering-active acupuncture needle. | Analytical chemistry 20110815 |
Common misconceptions about 5-aminosalicylates and thiopurines in inflammatory bowel disease. | World journal of gastroenterology 20110814 |
A cost effectiveness analysis of thiopurine methyltransferase testing for guiding 6-mercaptopurine dosing in children with acute lymphoblastic leukemia. | Pediatric blood & cancer 20110801 |
Varicella zoster meningoradiculitis in Crohn's disease treated with 6-mercaptopurine. | Inflammatory bowel diseases 20110801 |
Steroid dependency and pediatric inflammatory bowel disease in the era of immunomodulators--a population-based study. | Inflammatory bowel diseases 20110801 |
Reversible bone marrow necrosis after all-trans retinoic acid induction therapy for acute promyelocytic leukaemia. | Pathology 20110801 |
6-Mercaptopurine complexes with silver and gold ions: anti-tuberculosis and anti-cancer activities. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20110801 |
The pattern of gene expression and gene dose profiles of 6-Mercaptopurine- and 6-Thioguanine-resistant human leukemia cells. | Biochemical and biophysical research communications 20110722 |
Current treatment of ulcerative colitis. | World journal of gastroenterology 20110721 |
A microchip electrophoresis strategy with online labeling and chemiluminescence detection for simultaneous quantification of thiol drugs. | Journal of pharmaceutical and biomedical analysis 20110715 |
Escalating intravenous methotrexate improves event-free survival in children with standard-risk acute lymphoblastic leukemia: a report from the Children's Oncology Group. | Blood 20110714 |
Tacrolimus therapy as an alternative to thiopurines for maintaining remission in patients with refractory ulcerative colitis. | Journal of clinical gastroenterology 20110701 |
Detection of thiopurine methyltransferase activity in lysed red blood cells by means of lab-on-a-chip surface enhanced Raman spectroscopy (LOC-SERS). | Analytical and bioanalytical chemistry 20110701 |
Pre-analytic and analytic sources of variations in thiopurine methyltransferase activity measurement in patients prescribed thiopurine-based drugs: A systematic review. | Clinical biochemistry 20110701 |
Relapse rate following azathioprine withdrawal in maintaining remission for Crohn's disease: a meta-analysis. | Digestive diseases and sciences 20110701 |
'Tac'kling a difficult problem: using tacrolimus to maintain remission in ulcerative colitis. | Journal of clinical gastroenterology 20110701 |
Inflammatory bowel disease therapy: current state-of-the-art. | Current opinion in gastroenterology 20110701 |
Strength capacity in young patients who are receiving maintenance therapy for acute lymphoblastic leukemia: a case-control study. | Clinics (Sao Paulo, Brazil) 20110701 |
Insight into the 6-thiopurine-mediated termination of the invasive motility of tumor cells derived from inflammatory breast cancer. | Biochemistry 20110628 |
Quantum mechanical/molecular mechanical molecular dynamics and free energy simulations of the thiopurine S-methyltransferase reaction with 6-mercaptopurine. | The journal of physical chemistry. B 20110623 |
Nonmyeloablative, HLA-haploidentical bone marrow transplantation with high dose, post-transplantation cyclophosphamide. | Pediatric reports 20110622 |
Assessment of thiopurine S-methyltransferase activity in patients prescribed thiopurines: a systematic review. | Annals of internal medicine 20110621 |
Successful treatment of relapsed and refractory extramedullary acute promyelocytic leukemia with tamibarotene. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110620 |
Clinical usefulness of therapeutic drug monitoring of thiopurines in patients with inadequately controlled inflammatory bowel disease. | Inflammatory bowel diseases 20110601 |
Optimizing thiopurine therapy in inflammatory bowel disease. | Inflammatory bowel diseases 20110601 |
Thiopurine derivatives containing triazole and steroid: synthesis, antimalarial and antileishmanial activities. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20110601 |
Eruptive benign melanocytic naevi during immunosuppressive therapy in a Crohn's disease patient. | Inflammatory bowel diseases 20110601 |
Biotransformation of 6-thioguanine in inflammatory bowel disease patients: a comparison of oral and intravenous administration of 6-thioguanine. | British journal of pharmacology 20110601 |
Clinical course of Crohn's disease following treatment of lymphoma. | Inflammatory bowel diseases 20110601 |
Meta-analysis of randomised trials comparing thiopurines in childhood acute lymphoblastic leukaemia. | Leukemia 20110601 |
Severe muscular weakness as an isolated symptom of azathioprine hypersensitivity. | Inflammatory bowel diseases 20110601 |
Effects of methylenetetrahydrofolate reductase gene polymorphisms on toxicities during consolidation therapy in pediatric acute lymphoblastic leukemia in a Chinese population. | Leukemia & lymphoma 20110601 |
Female patients suffering from inflammatory bowel diseases are treated less frequently with immunosuppressive medication and have a higher disease activity: a subgroup analysis of a large multi-centre, prospective, internet-based study. | Journal of Crohn's & colitis 20110601 |
The effects of azathioprine on birth outcomes in women with inflammatory bowel disease (IBD). | Journal of Crohn's & colitis 20110601 |
The 6-MP versus placebo clinical trial in acute leukemia. | Clinical trials (London, England) 20110601 |
Toxicological pathology in the rat placenta. | Journal of toxicologic pathology 20110601 |
Thiopurine methyltransferase (TPMT) genotyping to predict myelosuppression risk. | PLoS currents 20110515 |
AIDA 0493 protocol for newly diagnosed acute promyelocytic leukemia: very long-term results and role of maintenance. | Blood 20110505 |
Outcome following thiopurine use in children with ulcerative colitis: a prospective multicenter registry study. | The American journal of gastroenterology 20110501 |
Risk of nonmelanoma skin cancer in patients with inflammatory bowel disease who use thiopurines is not increased. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20110501 |
Conventional medical management of inflammatory bowel disease. | Gastroenterology 20110501 |
Identification of BRAF mutations in eruptive melanocytic nevi: new insights into melanomagenesis? | Expert review of anticancer therapy 20110501 |
Azathioprine and mercaptopurine: lymphoma. | Prescrire international 20110501 |
Bayesian analysis for monotone hazard ratio. | Lifetime data analysis 20110401 |
Difficulties and possibilities with thiopurine therapy in inflammatory bowel disease--proceedings of the first Thiopurine Task Force meeting. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20110401 |
Treatment of autoimmune hepatitis: a review of current and evolving therapies. | Journal of gastroenterology and hepatology 20110401 |
6-Mercaptopurine reverses experimental vasospasm and alleviates the production of endothelins in NO-independent mechanism-a laboratory study. | Acta neurochirurgica 20110401 |
Practice patterns in the use of anti-tumor necrosis factor alpha agents in the management of Crohn's disease: a US national practice survey comparing experts and non-experts. | Digestive diseases and sciences 20110401 |
[Plasmacytoid dendritic cell tumor]. | Actas dermo-sifiliograficas 20110401 |
Long-term efficacy and safety of cyclosporine as a rescue therapy in acute, steroid-refractory severe ulcerative colitis: switching to infliximab is more effective than treating with concomitant immunomodulators. | Journal of clinical gastroenterology 20110401 |
Long-term results of AIEOP-8805 protocol for acute B-cell lymphoblastic leukemia of childhood. | Pediatric blood & cancer 20110401 |
Determinants of mercaptopurine toxicity in paediatric acute lymphoblastic leukemia maintenance therapy. | British journal of clinical pharmacology 20110401 |
Efficacy of immunosuppressive therapy for inflammatory bowel disease: a systematic review and meta-analysis. | The American journal of gastroenterology 20110401 |
Pyoderma gangrenosum in inflammatory bowel disease: the experience at Mater Health Services' Adult Hospital 1998-2009. | Journal of Crohn's & colitis 20110401 |
Antibacterial activity and phytochemical study of six medicinal plants used in Benin. | Pakistan journal of biological sciences : PJBS 20110401 |
Excited-state dynamics in 6-thioguanosine from the femtosecond to microsecond time scale. | The journal of physical chemistry. B 20110331 |
Treatment of acute promyelocytic leukaemia in the Jehovah's Witness population. | Annals of hematology 20110301 |
The role of standard-dose cytarabine in children with acute promyelocytic leukemia: a single-center experience. | Journal of pediatric hematology/oncology 20110301 |
6-Thioguanine reactivates epigenetically silenced genes in acute lymphoblastic leukemia cells by facilitating proteasome-mediated degradation of DNMT1. | Cancer research 20110301 |
Preoperative infliximab is not associated with an increased risk of short-term postoperative complications after restorative proctocolectomy and ileal pouch-anal anastomosis. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20110301 |
Clinical Pharmacogenetics Implementation Consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing. | Clinical pharmacology and therapeutics 20110301 |
Increased sensitivity to thiopurines in methylthioadenosine phosphorylase-deleted cancers. | Molecular cancer therapeutics 20110301 |
Severe hypoglycemic seizures in a child receiving 6-mercaptopurine. | Journal of pediatric hematology/oncology 20110301 |
Insulin infusion to treat severe hypertriglyceridemia associated with pegaspargase therapy: a case report. | Journal of pediatric hematology/oncology 20110301 |
Treatment outcome of all-trans retinoic acid/anthracycline combination chemotherapy and the prognostic impact of FLT3/ITD mutation in acute promyelocytic leukemia patients. | The Korean journal of hematology 20110301 |
Promyelocytic sarcoma of the sternum: a case report and review of the literature. | The Korean journal of hematology 20110301 |
Recent advances in the diagnosis and management of childhood acute promyelocytic leukemia. | Korean journal of pediatrics 20110301 |
Cyclosporine is safe and effective in patients with severe ulcerative colitis. | Journal of clinical gastroenterology 20110201 |
Prevention and treatment of postoperative Crohn's disease recurrence: an update for a new decade. | Current gastroenterology reports 20110201 |
Patient profiling for treatment toxicity: potential use of clinical and genomic factors. | Current oncology reports 20110201 |
Pregnancy outcome in patients with inflammatory bowel disease treated with thiopurines: cohort from the CESAME Study. | Gut 20110201 |
Effects of chronic immunosuppression on long-term oncologic outcomes for colorectal cancer patients undergoing surgery. | Annals of surgery 20110201 |
Assessment of non-cirrhotic portal hypertension associated with thiopurine therapy in inflammatory bowel disease. | Journal of Crohn's & colitis 20110201 |
Immunosuppressive therapy in children. | Journal of the Indian Medical Association 20110201 |
Pemphigus autoimmunity: hypotheses and realities. | Autoimmunity 20110201 |
Oral 5-aminosalicylic acid for maintenance of surgically-induced remission in Crohn's disease. | The Cochrane database of systematic reviews 20110119 |
Erythroblastic islands. | Blood 20110106 |
The relationship between fetal growth restriction and small placenta in 6-mercaptopurine exposed rat. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20110101 |
Cutaneous lymphoproliferative disorder complicating infectious mononucleosis in an immunosuppressed patient. | Pediatric dermatology 20110101 |
Cytogenetic instability in childhood acute lymphoblastic leukemia survivors. | Journal of biomedicine & biotechnology 20110101 |
Drug efflux transporter multidrug resistance-associated protein 5 affects sensitivity of pancreatic cancer cell lines to the nucleoside anticancer drug 5-fluorouracil. | Drug metabolism and disposition: the biological fate of chemicals 20110101 |
Methotrexate-induced subacute neurotoxicity in a child with acute lymphoblastic leukemia carrying genetic polymorphisms related to folate homeostasis. | American journal of hematology 20110101 |
Infliximab and/or azathioprine in the treatment of Crohn's disease-like complications after IPAA. | Diseases of the colon and rectum 20110101 |
Allopurinol might improve response to azathioprine and 6-mercaptopurine by correcting an unfavorable metabolite ratio. | Journal of gastroenterology and hepatology 20110101 |
Crohn's disease: a surgeon's perspective. | Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20110101 |
Ex vivo activity of cardiac glycosides in acute leukaemia. | PloS one 20110101 |
Azathioprine metabolite measurements are not useful in following treatment of autoimmune hepatitis in Alaska Native and other non-Caucasian people. | Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20110101 |
Managing pregnancy in inflammatory rheumatological diseases. | Arthritis research & therapy 20110101 |
Cdc45 limits replicon usage from a low density of preRCs in mammalian cells. | PloS one 20110101 |
Sex differences in drug disposition. | Journal of biomedicine & biotechnology 20110101 |
Adalimumab - an effective and promising treatment for patients with fistulizing Crohn's disease: a case series. | Journal of medical case reports 20110101 |
[Influence of exogeneous proteins on mutagenic process]. | TSitologiia i genetika 20110101 |
Presence of intestinal Mycobacterium avium subspecies paratuberculosis (MAP) DNA is not associated with altered MMP expression in ulcerative colitis. | BMC gastroenterology 20110101 |
Infliximab induces clonal expansion of γδ-T cells in Crohn's disease: a predictor of lymphoma risk? | PloS one 20110101 |
Successful treatment of adult onset Langerhans cell histiocytosis with multi-drug combination therapy. | Internal medicine (Tokyo, Japan) 20110101 |
Clinical relevance of thiopurine S-methyltransferase gene polymorphisms. | Neoplasma 20110101 |
Medication safety of five oral chemotherapies: a proactive risk assessment. | Journal of oncology practice 20110101 |
Safety and efficacy of the immunosuppressive agent 6-tioguanine in murine model of acute and chronic colitis. | BMC gastroenterology 20110101 |
A complicated case of tacrolimus-induced rapid remission after cesarean section in the early third trimester for refractory severe ulcerative colitis flaring in the initial period of gestation. | Case reports in gastroenterology 20110101 |
Current and emerging drugs for the treatment of inflammatory bowel disease. | Drug design, development and therapy 20110101 |
Spontaneous remission of Crohn's disease following a febrile infection: case report and literature review. | BMC gastroenterology 20110101 |
Glucose-6-phosphatase deficiency. | Orphanet journal of rare diseases 20110101 |
25-hydroxyvitamin D concentration is inversely associated with serum MMP-9 in a cross-sectional study of African American ESRD patients. | BMC nephrology 20110101 |
Disruption of learning processes by chemotherapeutic agents in childhood survivors of acute lymphoblastic leukemia and preclinical models. | Journal of Cancer 20110101 |
A sleeping phantom leg awakened following hemicolectomy, thrombosis, and chemotherapy: a case report. | Journal of medical case reports 20110101 |
Adverse events of thiopurine immunomodulators in patients with inflammatory bowel disease. | Gastroenterologia y hepatologia 20110101 |
An unusual cutaneous manifestation of Crohn's disease. | Skinmed 20110101 |
Predicting selective drug targets in cancer through metabolic networks. | Molecular systems biology 20110101 |
Infliximab therapy for moderately severe Crohn's disease and ulcerative colitis: a retrospective comparison over 6 years. | Clinical and experimental gastroenterology 20110101 |
Amebic encephalitis. | Surgical neurology international 20110101 |
Epidemiology of therapy-related myeloid neoplasms after treatment for pediatric acute lymphoblastic leukemia in the nordic countries. | Mediterranean journal of hematology and infectious diseases 20110101 |
Outcome of combination antiviral therapy in chronic hepatitis C virus infection during therapy of acute lymphoblastic leukemia. | Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20110101 |
Current and future role of biomarkers in Crohn's disease risk assessment and treatment. | Clinical and experimental gastroenterology 20110101 |
A case of Crohn's disease with improvement after azathioprine-induced pancytopenia. | Case reports in gastroenterology 20110101 |
Clinical therapeutics in pregnancy. | Journal of biomedicine & biotechnology 20110101 |
Rhodococcus equi venous catheter infection: a case report and review of the literature. | Journal of medical case reports 20110101 |
Current and emerging treatments for the management of myasthenia gravis. | Therapeutics and clinical risk management 20110101 |
Acute pancreatitis with saw palmetto use: a case report. | Journal of medical case reports 20110101 |
Mesenchymal stem cells: from experiment to clinic. | Fibrogenesis & tissue repair 20110101 |
Challenges in implementing individualized medicine illustrated by antimetabolite therapy of childhood acute lymphoblastic leukemia. | Clinical proteomics 20110101 |
Drug metabolizing enzyme activities versus genetic variances for drug of clinical pharmacogenomic relevance. | Clinical proteomics 20110101 |
A Burkitt's Lymphoma Case Mimicking Crohn's Disease: A Case Report. | Case reports in medicine 20110101 |
Clostridium difficile Infection and Inflammatory Bowel Disease: A Review. | Gastroenterology research and practice 20110101 |
Vitiligo during Treatment of Crohn's Disease with Adalimumab: Adverse Effect or Co-Occurrence? | Case reports in dermatology 20110101 |
Iridoid glycosides fraction of Folium syringae leaves modulates NF-κB signal pathway and intestinal epithelial cells apoptosis in experimental colitis. | PloS one 20110101 |
Eosinophilic enteritis confined to an ileostomy site. | Case reports in gastroenterology 20110101 |
Oral voclosporin: novel calcineurin inhibitor for treatment of noninfectious uveitis. | Clinical ophthalmology (Auckland, N.Z.) 20110101 |
Hypersensitivity reactions to anticancer agents: data mining of the public version of the FDA adverse event reporting system, AERS. | Journal of experimental & clinical cancer research : CR 20110101 |
Diabetes insipidus associated with a thickened pituitary stalk in a case of Langerhans Cell Histiocytosis. | Journal of pediatric neurosciences 20110101 |
Immunomodulators and immunosuppressants for Japanese patients with ulcerative colitis. | ISRN gastroenterology 20110101 |
Role of mucosal inflammation in eosinophilic esophagitis: review of the literature. | ISRN gastroenterology 20110101 |
Drug sensitivity patterns of HHV8 carrying body cavity lymphoma cell lines. | BMC cancer 20110101 |
Infliximab to treat Crohn's disease: an update. | Clinical and experimental gastroenterology 20110101 |
The use, safety, and effectiveness of herpes zoster vaccination in individuals with inflammatory and autoimmune diseases: a longitudinal observational study. | Arthritis research & therapy 20110101 |
A thiopurine drug inhibits West Nile virus production in cell culture, but not in mice. | PloS one 20110101 |
Ulcerative colitis in infancy. | Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20110101 |
Novel formulation of a methotrexate derivative with a lipid nanoemulsion. | International journal of nanomedicine 20110101 |
Treatment of Acute Promyelocytic Leukemia with AIDA Based Regimen. Update of a Tunisian Single Center Study. | Mediterranean journal of hematology and infectious diseases 20110101 |
'Il corpo ritrovato': dermocosmetological skin care project for the oncologic patient. | ISRN oncology 20110101 |
The reasons for discontinuation of infliximab treatment in patients with Crohn's disease: a review of practice at NHS teaching hospital. | ISRN gastroenterology 20110101 |
Mechanisms of neurotoxicity induced in the developing brain of mice and rats by DNA-damaging chemicals. | The Journal of toxicological sciences 20110101 |
Azathioprine induced cholestatic hepatitis. | Indian journal of pharmacology 20110101 |
Biologics in paediatric Crohn's disease. | Gastroenterology research and practice 20110101 |
Type 1 autoimmune pancreatitis. | Orphanet journal of rare diseases 20110101 |
Characterization of Abcc4 gene amplification in stepwise-selected mouse J774 macrophages resistant to the topoisomerase II inhibitor ciprofloxacin. | PloS one 20110101 |
Thiopurine methyltransferase predicts the extent of cytotoxicty and DNA damage in astroglial cells after thioguanine exposure. | PloS one 20110101 |
Peripheral Blood CD64 Levels Decrease in Crohn's Disease following Granulocyte and Monocyte Adsorptive Apheresis. | Case reports in gastroenterology 20110101 |
Clinical features and treatment outcome of acute promyelocytic leukemia patients treated at cairo national cancer institute in egypt. | Mediterranean journal of hematology and infectious diseases 20110101 |
Emerging role of rasburicase in the management of increased plasma uric acid levels in patients with hematologic malignancies. | Journal of blood medicine 20110101 |
Nevogenesis: a benign metastatic process? | ISRN dermatology 20110101 |
Measures of rheumatoid arthritis disease activity in Australian clinical practice. | ISRN rheumatology 20110101 |
Catheter-Related Acremonium kiliense Fungemia in a Patient with Ulcerative Colitis under Treatment with Infliximab. | Case reports in infectious diseases 20110101 |
Gold nanoparticles in biology and medicine: recent advances and prospects. | Acta naturae 20110101 |
Compliance with a protocol for acute lymphoblastic leukemia in childhood. | Revista brasileira de hematologia e hemoterapia 20110101 |
Effect of mitoxantrone on outcome of children with first relapse of acute lymphoblastic leukaemia (ALL R3): an open-label randomised trial. | Lancet (London, England) 20101211 |
Frequency of TPMT alleles in Indian patients with acute lymphatic leukemia and effect on the dose of 6-mercaptopurine. | Medical oncology (Northwood, London, England) 20101201 |
Heritable and non-genetic factors as variables of pharmacologic phenotypes in lymphoblastoid cell lines. | The pharmacogenomics journal 20101201 |
Combination biological and surgical therapy in an adolescent presenting with highly destructive perianal Crohn disease. | Journal of pediatric gastroenterology and nutrition 20101201 |
A single-center experience with methotrexate after thiopurine therapy in pediatric Crohn disease. | Journal of pediatric gastroenterology and nutrition 20101201 |
A predictive ligand-based Bayesian model for human drug-induced liver injury. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
Ecto-5'-nucleotidase and thiopurine cellular circulation: association with cytotoxicity. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
Preparing the patient for immunosuppressive therapy. | Current gastroenterology reports 20101201 |
Thiopurines in Crohn's disease, is there something new? | Expert opinion on drug metabolism & toxicology 20101201 |
Infliximab, azathioprine or combination therapy in the treatment of active Crohn's disease. | Expert review of gastroenterology & hepatology 20101201 |
Steady-state of azathioprine during initiation treatment of pediatric inflammatory bowel disease. | Journal of Crohn's & colitis 20101201 |
Modeling mechanisms of in vivo variability in methotrexate accumulation and folate pathway inhibition in acute lymphoblastic leukemia cells. | PLoS computational biology 20101201 |
Outcome of childhood acute promyelocytic leukemia treated using a modified AIDA protocol. | The Korean journal of hematology 20101201 |
Cancer pharmacogenomics and pharmacoepidemiology: setting a research agenda to accelerate translation. | Journal of the National Cancer Institute 20101117 |
Thiol with an unusual adsorption-desorption behavior: 6-mercaptopurine on Au(111). | Langmuir : the ACS journal of surfaces and colloids 20101116 |
Arsenic trioxide improves event-free and overall survival for adults with acute promyelocytic leukemia: North American Leukemia Intergroup Study C9710. | Blood 20101111 |
Azathioprine-induced hypersensitivity hepatitis: tolerance to 6-mercaptopurine. | Inflammatory bowel diseases 20101101 |
The inflammatory bowel diseases and ambient air pollution: a novel association. | The American journal of gastroenterology 20101101 |
Acute pancreatitis in type 2 diabetes treated with exenatide or sitagliptin: a retrospective observational pharmacy claims analysis. | Diabetes care 20101101 |
Activating BRAF mutations in eruptive melanocytic naevi. | The British journal of dermatology 20101101 |
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
Childhood acute lymphoblastic leukemia in Turkey: factors influencing treatment and outcome: a single center experience. | Journal of pediatric hematology/oncology 20101101 |
Allopurinol-thiopurine combination therapy in inflammatory bowel disease: are there genetic clues to this puzzle? | Pharmacogenomics 20101101 |
Hepatosplenic T-cell lymphoma and inflammatory bowel disease. | Journal of Crohn's & colitis 20101101 |
A prospective evaluation of the impact of allopurinol in pediatric and adult IBD patients with preferential metabolism of 6-mercaptopurine to 6-methylmercaptopurine. | Journal of Crohn's & colitis 20101101 |
Adherence of gastroenterologists to European Crohn's and Colitis Organisation consensus on ulcerative colitis: a real-life survey in Spain. | Journal of Crohn's & colitis 20101101 |
Long-term efficacy of adalimumab in paediatric Crohn's disease patients naïve to other anti-TNF therapies. | Journal of Crohn's & colitis 20101101 |
Usefulness of the measurement of azathioprine metabolites in the assessment of non-adherence. | Journal of Crohn's & colitis 20101101 |
[A successful case of tanshinone II A treatment for relapsed acute promyelocytic leukemia after maintainance therapy of all-trans retinoic acid and arsenic trioxide]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20101101 |
Brief report: Barriers to treatment adherence in pediatric inflammatory bowel disease. | Journal of pediatric psychology 20101001 |
Merkel cell carcinoma metastatic to the thyroid gland: Aspiration findings and differential diagnosis. | Diagnostic cytopathology 20101001 |
The multidrug-resistance protein 4 polymorphism is a new factor accounting for thiopurine sensitivity in Japanese patients with inflammatory bowel disease. | Journal of gastroenterology 20101001 |
Treatment of relapsing mild-to-moderate ulcerative colitis with the probiotic VSL#3 as adjunctive to a standard pharmaceutical treatment: a double-blind, randomized, placebo-controlled study. | The American journal of gastroenterology 20101001 |
Genetic analysis of thiopurine methyltransferase polymorphism in the Jordanian population. | European journal of clinical pharmacology 20101001 |
Allopurinol salvage therapy in pediatric overlap autoimmune hepatitis-primary sclerosing cholangitis with 6-MMP toxicity. | Journal of pediatric gastroenterology and nutrition 20101001 |
Vaccinations in patients with immune-mediated inflammatory diseases. | Rheumatology (Oxford, England) 20101001 |
Renal cell carcinoma and acute promyelocytic leukemia: a nonrandom association? | American journal of hematology 20101001 |
Combination of the histone deacetylase inhibitor valproic acid with oral hydroxyurea or 6-mercaptopurin can be safe and effective in patients with advanced acute myeloid leukaemia--a report of five cases. | Hematology (Amsterdam, Netherlands) 20101001 |
Monitoring 6-thioguanine nucleotide concentrations in Japanese children and adolescents with inflammatory bowel disease. | Journal of gastroenterology and hepatology 20101001 |
Hepatosplenic T-cell lymphoma in inflammatory bowel disease: a possible thiopurine-induced chromosomal abnormality. | The American journal of gastroenterology 20101001 |
Thiopurine therapy in inflammatory bowel disease. | Expert review of gastroenterology & hepatology 20101001 |
Combination of thiopurines and allopurinol: adverse events and clinical benefit in IBD. | Journal of Crohn's & colitis 20101001 |
Tolerability and usefulness of mercaptopurine in azathioprine-intolerant Japanese patients with ulcerative colitis. | Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 20101001 |
An unusual case of capecitabine hyperpigmentation: Is hyperpigmentation a part of hand-foot syndrome or a separate entity? | Indian journal of pharmacology 20101001 |
Regulation of Nur77 protein turnover through acetylation and deacetylation induced by p300 and HDAC1. | Biochemical pharmacology 20100915 |
Substrate orientation and catalytic specificity in the action of xanthine oxidase: the sequential hydroxylation of hypoxanthine to uric acid. | The Journal of biological chemistry 20100903 |
Bone marrow suppression in the setting of normal thiopurine methyltransferase phenotype testing. | Clinical pediatrics 20100901 |
Thiopurine pathway. | Pharmacogenetics and genomics 20100901 |
The impact of high-dose methotrexate on intracellular 6-mercaptopurine disposition during interval therapy of childhood acute lymphoblastic leukemia. | Cancer chemotherapy and pharmacology 20100901 |
Treatment-associated acute myeloid leukemia in a patient with Crohn's disease on 6-mercaptopurine. | Inflammatory bowel diseases 20100901 |
Thiopurine therapy in inflammatory bowel disease patients: analyses of two 8-year intercept cohorts. | Inflammatory bowel diseases 20100901 |
Natural history of Crohn's disease in a population-based cohort from Cardiff (1986-2003): a study of changes in medical treatment and surgical resection rates. | Gut 20100901 |
Outcomes of pregnancies fathered by inflammatory bowel disease patients exposed to thiopurines. | The American journal of gastroenterology 20100901 |
[Remission of ulcerative colitis after appendectomy: a case report]. | The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20100901 |
Cologastric fistula with a foreign body in a patient with Crohn's disease. | The Yale journal of biology and medicine 20100901 |
Acquired factor VIII deficiency after consuming the dried gallbladder of a cobra, Naja naja. | The Korean journal of hematology 20100901 |
Optimizing therapy with 6-mercaptopurine and azathioprine: to measure or not to measure? | Therapeutic advances in gastroenterology 20100901 |
Change in the treatment strategy for pediatric Crohn's disease. | Korean journal of pediatrics 20100901 |
CNS relapse in acute promyeloctyic leukemia. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100820 |
DNA incorporation of 6-thioguanine nucleotides during maintenance therapy of childhood acute lymphoblastic leukaemia and non-Hodgkin lymphoma. | Cancer chemotherapy and pharmacology 20100801 |
Thiopurine maintenance therapy for ulcerative colitis: the clinical significance of monitoring 6-thioguanine nucleotide. | Inflammatory bowel diseases 20100801 |
Thiopurine S-methyltransferase gene polymorphism and 6-mercaptopurine dose intensity in Indian children with acute lymphoblastic leukemia. | Leukemia research 20100801 |
Immunosuppressive effects via human intestinal dendritic cells of probiotic bacteria and steroids in the treatment of acute ulcerative colitis. | Inflammatory bowel diseases 20100801 |
Pyridoxine treatment of vincristine-induced cranial polyneuropathy in an adult patient with acute lymphocytic leukemia: Case report and review of the literature. | Leukemia research 20100801 |
Nuclear receptor Nur77 suppresses inflammatory response dependent on COX-2 in macrophages induced by oxLDL. | Journal of molecular and cellular cardiology 20100801 |
6-mercaptopurine inhibits atherosclerosis in apolipoprotein e*3-leiden transgenic mice through atheroprotective actions on monocytes and macrophages. | Arteriosclerosis, thrombosis, and vascular biology 20100801 |
6-Mercaptopurine exerts an immunomodulatory and neuroprotective effect on permanent focal cerebral occlusion in rats. | Acta neurochirurgica 20100801 |
Monitoring of azathioprine metabolites in pediatric patients with autoimmune hepatitis. | Therapeutic drug monitoring 20100801 |
Immunosuppressive treatments in Crohn's disease induce myelodysplasia and leukaemia. | American journal of hematology 20100801 |
Randomized trial to compare LSA2L2-type maintenance therapy to daily 6-mercaptopurine and weekly methotrexate with vincristine and dexamethasone pulse for children with acute lymphoblastic leukemia. | Pediatric blood & cancer 20100801 |
Langerhans cell histiocytosis in a child with non-Hodgkin lymphoma. | Journal of pediatric hematology/oncology 20100801 |
6-Mercaptopurine, monocytes, and atherosclerosis. | Arteriosclerosis, thrombosis, and vascular biology 20100801 |
Complete paraplegia after nelarabine treatment in a T-cell acute lymphoblastic leukemia adult patient. | American journal of hematology 20100801 |
IBD: Switching metabolism-can two drugs be better than one? | Nature reviews. Gastroenterology & hepatology 20100801 |
The genetics of inflammatory bowel disease: diagnostic and therapeutic implications. | World journal of pediatrics : WJP 20100801 |
Differences among allelic variants of human glutathione transferase A2-2 in the activation of azathioprine. | Chemico-biological interactions 20100730 |
Thiopurine S-methyltransferase polymorphisms and thiopurine toxicity in treatment of inflammatory bowel disease. | World journal of gastroenterology 20100707 |
Review article: malignancy on thiopurine treatment with special reference to inflammatory bowel disease. | Alimentary pharmacology & therapeutics 20100701 |
A 30-month-old child with acute renal failure due to primary renal cytotoxic T-cell lymphoma. | The American journal of surgical pathology 20100701 |
LC-MS/MS coupled with stable isotope dilution method for the quantification of 6-thioguanine and S(6)-methylthioguanine in genomic DNA of human cancer cells treated with 6-thioguanine. | Analytical chemistry 20100701 |
Crystallographic and docking studies of purine nucleoside phosphorylase from Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry 20100701 |
Influence of 5-aminosalicylic acid on 6-thioguanosine phosphate metabolite levels: a prospective study in patients under steady thiopurine therapy. | British journal of pharmacology 20100701 |
Postoperative Crohn's disease: how can we prevent it? | Expert review of clinical immunology 20100701 |
Use of immunomodulators and biologic therapies in children with inflammatory bowel disease. | Expert review of clinical immunology 20100701 |
[A case of hemophagocytic syndrome in an ulcerative colitis patient]. | The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20100701 |
Photodynamic therapy for multi-resistant cutaneous Langerhans cell histiocytosis. | Rare tumors 20100630 |
Azathioprine or 6-mercaptopurine for induction of remission in Crohn's disease. | The Cochrane database of systematic reviews 20100616 |
Using adaptive model predictive control to customize maintenance therapy chemotherapeutic dosing for childhood acute lymphoblastic leukemia. | Journal of theoretical biology 20100607 |
Response to medical treatment in patients with Crohn's disease: the role of NOD2/CRAD15, disease phenotype, and age of diagnosis. | Digestive diseases and sciences 20100601 |
Health-related quality of life of youth with inflammatory bowel disease: a comparison with published data using the PedsQL 4.0 generic core scales. | Inflammatory bowel diseases 20100601 |
Azathioprine or mercaptopurine-induced acute pancreatitis is not a disease-specific phenomenon. | Alimentary pharmacology & therapeutics 20100601 |
Limited stability of thiopurine metabolites in blood samples: relevant in research and clinical practise. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100601 |
Central nervous system complications during treatment of acute lymphoblastic leukemia in a single pediatric institution. | Leukemia & lymphoma 20100601 |
Novel strategies in the thiopurine treatment of inflammatory bowel disease. | Nucleosides, nucleotides & nucleic acids 20100601 |
How should thiopurine treatment be monitored?--methodological aspects. | Nucleosides, nucleotides & nucleic acids 20100601 |
Seronegative polyarthritis as severe systemic disease. | The Netherlands journal of medicine 20100601 |
Subcutaneous panniculitis-like T-cell lymphoma in a 19 month-old boy: a case report. | Collegium antropologicum 20100601 |
Localization of the magnetic equivalent of the ERN and induced oscillatory brain activity. | NeuroImage 20100515 |
Impact of concomitant immunomodulator use on long-term outcomes in patients receiving scheduled maintenance infliximab. | Digestive diseases and sciences 20100501 |
Safety of immunomodulators and biologics for the treatment of inflammatory bowel disease during pregnancy and breast-feeding. | Inflammatory bowel diseases 20100501 |
The impact of thiopurines on the risk of surgical recurrence in patients with Crohn's disease after first intestinal surgery. | The American journal of gastroenterology 20100501 |
Reaction mechanisms of allicin and allyl-mixed disulfides with proteins and small thiol molecules. | European journal of medicinal chemistry 20100501 |
Prediction of 6-thioguanine nucleotides levels in Japanese patients with inflammatory bowel diseases during long-term thiopurine administration. | Scandinavian journal of gastroenterology 20100501 |
6-Mercaptopurine attenuates adhesive molecules in experimental vasospasm. | Acta neurochirurgica 20100501 |
Desensitization of patients with allergic reactions to immunosuppressives in the treatment of inflammatory bowel disease. | Expert opinion on drug safety 20100501 |
Prospective study of hemostatic alterations in children with acute lymphoblastic leukemia. | American journal of hematology 20100501 |
Neurological complications during treatment of childhood cancer: mind Wernicke encephalopathy. | Pediatric hematology and oncology 20100501 |
trans-Tetra-aqua-bis{(E)-2-cyano-1-[(ethoxy-carbon-yl)methyl-sulfan-yl]-2-(1-naphthyl-amino-carbon-yl)ethene-1-thiol-ato}calcium(II) diethyl ether disolvate. | Acta crystallographica. Section E, Structure reports online 20100501 |
Benefits of the intermittent use of 6-mercaptopurine and methotrexate in maintenance treatment for low-risk acute lymphoblastic leukemia in children: randomized trial from the Brazilian Childhood Cooperative Group--protocol ALL-99. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100410 |
Dynamic regulation of a metabolic multi-enzyme complex by protein kinase CK2. | The Journal of biological chemistry 20100409 |
Oral 6-mercaptopurine versus oral 6-thioguanine and veno-occlusive disease in children with standard-risk acute lymphoblastic leukemia: report of the Children's Oncology Group CCG-1952 clinical trial. | Blood 20100408 |
Design and in vitro evaluation of branched peptide conjugates: turning nonspecific cytotoxic drugs into tumor-selective agents. | ChemMedChem 20100406 |
Recent advances in the management of distal ulcerative colitis. | World journal of gastrointestinal pharmacology and therapeutics 20100406 |
Contemporary challenges in mastocytosis. | Clinical reviews in allergy & immunology 20100401 |
Central nervous system involvement at the time of presentation in acute promyelocytic leukemia. | Pediatric blood & cancer 20100401 |
Prospective bone ultrasound patterns during childhood acute lymphoblastic leukemia treatment. | Bone 20100401 |
Ongoing remission after intensive ALL-type chemotherapy in pediatric intestinal T-cell lymphoma. | Pediatric blood & cancer 20100401 |
Supervising the supervisors--procedural training and supervision in internal medicine residency. | Journal of general internal medicine 20100401 |
Pancreatitis in inflammatory bowel diseases. | Journal of clinical gastroenterology 20100401 |
Cytomegalovirus infection in patients with active inflammatory bowel disease. | Digestive diseases and sciences 20100401 |
The degree of myelosuppression during maintenance therapy of adolescents with B-lineage intermediate risk acute lymphoblastic leukemia predicts risk of relapse. | Leukemia 20100401 |
Hepatosplenic T-cell lymphoma in a young man with Crohn's disease: case report and literature review. | Clinical lymphoma, myeloma & leukemia 20100401 |
Disseminated coccidioidomycosis in a patient managed with adalimumab for Crohn's disease. | Nature reviews. Gastroenterology & hepatology 20100401 |
[Tolerability of 6-mercaptopurine in children with acute lymphoblastic leukemia]. | Zhonghua er ke za zhi = Chinese journal of pediatrics 20100401 |
Very long-term outcome of acute promyelocytic leukemia after treatment with all-trans retinoic acid and chemotherapy: the European APL Group experience. | Blood 20100304 |
Preoperative infliximab treatment in patients with ulcerative and indeterminate colitis does not increase rate of conversion to emergent and multistep abdominal surgery. | International journal of colorectal disease 20100301 |
Azathioprine, mucosal healing in ulcerative colitis, and the chemoprevention of colitic cancer: a clinical-practice-based forecast. | Inflammation & allergy drug targets 20100301 |
Low-dose azathioprine or mercaptopurine in combination with allopurinol can bypass many adverse drug reactions in patients with inflammatory bowel disease. | Alimentary pharmacology & therapeutics 20100301 |
Anticancer agents against malaria: time to revisit? | Trends in parasitology 20100301 |
Outpatient care for inflammatory bowel disease at a primary referral hospital in Turin. | Minerva gastroenterologica e dietologica 20100301 |
Significance of myeloid antigen expression in precursor T lymphoblastic lymphoma. | Chinese journal of cancer 20100301 |
Human lymphoblastoid cell line panels: novel tools for assessing shared drug pathways. | Pharmacogenomics 20100301 |
Juvenile myelomonocytic leukemia with PTPN11 mutation in a 23-month-old girl. | Collegium antropologicum 20100301 |
N,N'-Bis(2-chloroethyl)-N-nitrosourea (BCNU)-induced Apoptosis of Neural Progenitor Cells in the Developing Fetal Rat Brain. | Journal of toxicologic pathology 20100301 |
13C chemical shift tensors in hypoxanthine and 6-mercaptopurine: effects of substitution, tautomerism, and intermolecular interactions. | The journal of physical chemistry. A 20100204 |
Toxic non-resorptive internal hydrocephalus as a result of haemorrhagic ventriculitis during induction chemotherapy of Bcr-Abl positive acute lymphoblastic leukaemia. | Annals of hematology 20100201 |
Algorithms outperform metabolite tests in predicting response of patients with inflammatory bowel disease to thiopurines. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20100201 |
Central variant of posterior reversible encephalopathy syndrome in systemic lupus erythematosus: new associations? | Lupus 20100201 |
Correlation of genotypes for thiopurine methyltransferase and inosine triphosphate pyrophosphatase with long-term clinical outcomes in Korean patients with inflammatory bowel diseases during treatment with thiopurine drugs. | Journal of human genetics 20100201 |
Long-term results of NOPHO ALL-92 and ALL-2000 studies of childhood acute lymphoblastic leukemia. | Leukemia 20100201 |
Long-term results of the pediatric oncology group studies for childhood acute lymphoblastic leukemia 1984-2001: a report from the children's oncology group. | Leukemia 20100201 |
'I am older, not elderly,' said the patient with acute myeloid leukemia. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100201 |
Building a tiered approach to in vitro predictive toxicity screening: a focus on assays with in vivo relevance. | Combinatorial chemistry & high throughput screening 20100201 |
Incretin-based therapies for the treatment of type 2 diabetes: evaluation of the risks and benefits. | Diabetes care 20100201 |
Are patients with intermediate TPMT activity at increased risk of myelosuppression when taking thiopurine medications? | Pharmacogenomics 20100201 |
Oedema and Crohn's disease. | The Netherlands journal of medicine 20100201 |
Thiopurine S-methyltransferase genotype and the use of thiopurines in paediatric inflammatory bowel disease Greek patients. | Journal of clinical pharmacy and therapeutics 20100201 |
Clinical case of acute myeloblastic leukemia with t(8;21)(q22;q22) in a patient with Klinefelter's syndrome. | Hematology reports 20100126 |
Modulating dendritic cells (DC) from immunogenic to tolerogenic responses: a novel mechanism of AZA/6-MP. | Journal of neuroimmunology 20100125 |
Mercaptopurine rescue after azathioprine-induced liver injury in inflammatory bowel disease. | Alimentary pharmacology & therapeutics 20100101 |
Flow injection chemiluminescence determination of 6-mercaptopurine based on a new system of potassium permanganate-thioacetamide-sodium hexametaphosphate. | Luminescence : the journal of biological and chemical luminescence 20100101 |
MTHFR and TYMS genotypes influence TPMT activity and its differential modulation in males and females. | Clinical biochemistry 20100101 |
Pro-inflammatory and pro-coagulant properties of 6-thioguanine and 6-mercaptopurine: implications for their potential role in the development of sinusoidal obstruction syndrome. | Leukemia & lymphoma 20100101 |
Characterisation and utility of thiopurine methyltransferase and thiopurine metabolite measurements in autoimmune hepatitis. | Journal of hepatology 20100101 |
Methylene tetrahydrofolate reductase gene polymorphism in Egyptian children with acute lymphoblastic leukemia. | Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20100101 |
Cutaneous xanthogranulomas, hepatosplenomegaly, anemia, and thrombocytopenia as presenting signs of juvenile myelomonocytic leukemia. | American journal of clinical dermatology 20100101 |
Genetic polymorphism of inosine-triphosphate-pyrophosphatase influences mercaptopurine metabolism and toxicity during treatment of acute lymphoblastic leukemia individualized for thiopurine-S-methyl-transferase status. | Expert opinion on drug safety 20100101 |
Mercaptopurine-induced fever: hypersensitivity reaction in a patient with acute lymphoblastic leukemia. | Pharmacotherapy 20100101 |
Idarubicin plus behenoyl cytarabine and 6-thioguanine compares favorably with idarubicin plus cytarabine-based regimen for children with previously untreated acute myeloid leukemia: 10-year retrospective, multicenter study in Korea. | Journal of Korean medical science 20100101 |
Recurrence and impact of postoperative prophylaxis in laparoscopically treated primary ileocolic Crohn disease. | Archives of surgery (Chicago, Ill. : 1960) 20100101 |
Clinical profile, treatment, and visual outcome of ampiginous choroiditis. | Ocular immunology and inflammation 20100101 |
[Immunosuppressive therapy update 2010 for ANCA-associated glomerulonephritis and intractable nephrotic syndrome]. | Nihon Jinzo Gakkai shi 20100101 |
Management of hyperuricemia in gout: focus on febuxostat. | Clinical interventions in aging 20100101 |
The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease. | PloS one 20100101 |
The effects of thiopurine therapy on health-related quality of life in Inflammatory Bowel Disease patients. | BMC gastroenterology 20100101 |
Pharmacogenetics of thiopurines in inflammatory bowel disease. | Current pharmaceutical design 20100101 |
Influences of thiopurine methyltransferase genotype and activity on thiopurine-induced leukopenia in Korean patients with inflammatory bowel disease: a retrospective cohort study. | Journal of clinical gastroenterology 20100101 |
An ab initio and AIM investigation into the hydration of 2-thioxanthine. | Chemistry Central journal 20100101 |
Biology-driven cancer drug development: back to the future. | BMC biology 20100101 |
Rapid selection and proliferation of CD133+ cells from cancer cell lines: chemotherapeutic implications. | PloS one 20100101 |
Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset. | PloS one 20100101 |
The thioamides methimazole and thiourea inhibit growth of M. avium Subspecies paratuberculosis in culture. | PloS one 20100101 |
Photo-oxidation of 6-thioguanine by UVA: the formation of addition products with low molecular weight thiol compounds. | Photochemistry and photobiology 20100101 |
Experimental human cell and tissue models of pemphigus. | Dermatology research and practice 20100101 |
Long-term follow-up with Granulocyte and Monocyte Apheresis re-treatment in patients with chronically active inflammatory bowel disease. | BMC gastroenterology 20100101 |
[Therapeutic drug monitoring of 6-thioguanine nucleotides in paediatric acute lymphoblastic leukaemia: interest and limits]. | Therapie 20100101 |
Guilt by association - what is the true risk of malignancy in children treated with etanercept for JIA? | Pediatric rheumatology online journal 20100101 |
Langerhans cell histiocytosis of the petrous bone with sudden sensorineural hearing loss. Case report. | Neurologia medico-chirurgica 20100101 |
Miss to the right: the effect of attentional asymmetries on goal-kicking. | PloS one 20100101 |
Concurrent sternal and pulmonary foci of Langerhans cell histiocytosis. | Annals of thoracic medicine 20100101 |
[Acute lymphoblastic leukaemia in children and adolescents: chance of cure now higher than 80%]. | Nederlands tijdschrift voor geneeskunde 20100101 |
FragViz: visualization of fragmented networks. | BMC bioinformatics 20100101 |
State-of-the-art: Immunosuppression and biologic therapy. | Digestive diseases (Basel, Switzerland) 20100101 |
How rapidly should remission be achieved? | Digestive diseases (Basel, Switzerland) 20100101 |
Fistula treatment: The unresolved challenge. | Digestive diseases (Basel, Switzerland) 20100101 |
Predicting enzyme targets for cancer drugs by profiling human metabolic reactions in NCI-60 cell lines. | BMC bioinformatics 20100101 |
Elevated Levels of DNA Strand Breaks Induced by a Base Analog in the Human Cell Line with the P32T ITPA Variant. | Journal of nucleic acids 20100101 |
Hydronephrosis Resulting from Bilateral Ureteral Stenosis: A Late Complication of Polyoma BK Virus Cystitis? | Journal of transplantation 20100101 |
Dent's disease. | Orphanet journal of rare diseases 20100101 |
Esophageal Crohn's disease treated 'topically' with swallowed aerosolized budesonide. | Case reports in medicine 20100101 |
Genetic variations in human glutathione transferase enzymes: significance for pharmacology and toxicology. | Human genomics and proteomics : HGP 20100101 |
[Guideline 'Diagnosis and treatment of inflammatory bowel disease in children']. | Nederlands tijdschrift voor geneeskunde 20100101 |
Drug interaction and pharmacist. | Journal of young pharmacists : JYP 20100101 |
Use of methotrexate in patients with inflammatory bowel diseases. | Clinical and experimental rheumatology 20100101 |
Usefulness of thiopurine methyltransferase and thiopurine metabolite analysis in clinical practice in patients with inflammatory bowel diseases. | Acta gastro-enterologica Belgica 20100101 |
Vaccination and infection prevention in inflammatory bowel disease. | F1000 medicine reports 20100101 |
Immunomodulators for all patients with inflammatory bowel disease? | Therapeutic advances in gastroenterology 20100101 |
Monitoring treatment response of childhood acute lymphocytic leukemia with certain molecular and biochemical markers. | Journal of biochemical and molecular toxicology 20100101 |
Langerhan's cell histiocytosis: A single institutional experience. | Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology 20100101 |
Personalized medicine: FAQs. | Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology 20100101 |
Early Detection of t(8;21) Chromosomal Translocations During Treatment of PML-RARA Positive Acute Promyelocytic Leukemia: A Case Study. | Clinical Medicine Insights. Oncology 20100101 |
Successful long-term use of infliximab in refractory pouchitis in an adolescent. | Gastroenterology research and practice 20100101 |
[A case of the association of acute lymphoblastic lymphoma with active tuberculosis in the child: a Malian case]. | Le Mali medical 20100101 |
Stem cell therapeutics: potential in the treatment of inflammatory bowel disease. | Clinical and experimental gastroenterology 20100101 |
Infliximab therapy in pediatric Crohn's disease: a review. | Clinical and experimental gastroenterology 20100101 |
Advances in the management of gout: critical appraisal of febuxostat in the control of hyperuricemia. | International journal of nephrology and renovascular disease 20100101 |
New and improved strategies for the treatment of gout. | International journal of nephrology and renovascular disease 20100101 |
Intracranial Rosai Dorfman Disease: report of three cases and literature review. | Asian journal of neurosurgery 20100101 |
Design and development of hydrogel nanoparticles for mercaptopurine. | Journal of advanced pharmaceutical technology & research 20100101 |
Nanotechnology for early cancer detection. | Sensors (Basel, Switzerland) 20100101 |
Impact of anti-cancer drugs and other determinants on serum protein binding of morphine 6-glucuronide. | Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20100101 |
Microprocessor in controlled transdermal drug delivery of anti-cancer drugs. | Journal of materials science. Materials in medicine 20091201 |
Peripheral neuropathy with infliximab therapy in inflammatory bowel disease. | Inflammatory bowel diseases 20091201 |
A phase II study of Campath-1H in children with relapsed or refractory acute lymphoblastic leukemia: a Children's Oncology Group report. | Pediatric blood & cancer 20091201 |
Captopril and 6-mercaptopurine: whose SH possesses higher antioxidant ability? | European journal of medicinal chemistry 20091201 |
Population pharmacokinetic analysis of infliximab in patients with ulcerative colitis. | European journal of clinical pharmacology 20091201 |
Immunomodulator agent-related lymphoproliferative disorders. | Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20091201 |
Immunomodulation does not alter histology in resected Crohn's disease. | Techniques in coloproctology 20091201 |
[Individual and strain differences of aldehyde oxidase in the rat]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20091201 |
Secondary osteosarcoma arising after treatment for childhood hematologic malignancies. | Upsala journal of medical sciences 20091201 |
[Significant changes of pharmacotherapy in gastroenterological rehabilitation of Crohn's disease]. | Die Rehabilitation 20091201 |
Partition coefficients of some purine derivatives and its application to pharmacokinetics. | Die Pharmazie 20091201 |
Azathioprine induced pneumonitis in a patient with ulcerative colitis. | Journal of Crohn's & colitis 20091201 |
6-Benzyl-sulfanyl-9H-purine. | Acta crystallographica. Section E, Structure reports online 20091201 |
Outcome and haemato-toxicity of two chemotherapy regimens for childhood non-Hodgkin's lymphoma in a Kenyan hospital. | East African medical journal 20091201 |
Additional chromosomal abnormalities and their prognostic significance in adult Philadelphia-positive acute lymphoblastic leukemia: with or without imatinib in chemotherapy. | Annals of hematology 20091101 |
2-Arylbenzimidazoles as antiviral and antiproliferative agents--Part 2. | Medicinal chemistry (Shariqah (United Arab Emirates)) 20091101 |
Timing of myelosuppression during thiopurine therapy for inflammatory bowel disease: implications for monitoring recommendations. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20091101 |
The development of an objective methodology to measure medication adherence to oral thiopurines in paediatric patients with acute lymphoblastic leukaemia--an exploratory study. | European journal of clinical pharmacology 20091101 |
Effects of interactions of antibacterial drugs with each other and with 6-mercaptopurine on in vitro growth of Mycobacterium avium subspecies paratuberculosis. | The Journal of antimicrobial chemotherapy 20091101 |
Therapy of inflammatory bowel diseases in pregnancy and lactation. | Expert opinion on drug safety 20091101 |
Random serum methotrexate determinations for assessing compliance with maintenance therapy for childhood acute lymphoblastic leukemia. | Leukemia & lymphoma 20091101 |
Patent watch. Drug metabolite claims are patentable. | Nature reviews. Drug discovery 20091101 |
Orange juice and hesperetin supplementation to hyperuricemic rats alter oxidative stress markers and xanthine oxidoreductase activity. | Journal of clinical biochemistry and nutrition 20091101 |
The cytotoxic effects of gemtuzumab ozogamicin (mylotarg) in combination with conventional antileukemic agents by isobologram analysis in vitro. | Anticancer research 20091101 |
On therapeutic drug monitoring of thiopurines in inflammatory bowel disease; pharmacology, pharmacogenomics, drug intolerance and clinical relevance. | Current drug metabolism 20091101 |
Prospective study of the effects of concomitant medications on thiopurine metabolism in inflammatory bowel disease. | Alimentary pharmacology & therapeutics 20091015 |
Azathioprine or 6-mercaptopurine for induction of remission in Crohn's disease. | The Cochrane database of systematic reviews 20091007 |
Severe refractory orofacial Crohn's disease: report of a case. | Digestive diseases and sciences 20091001 |
The race and dose of chemotherapy should be considered for optimizing maintenance therapy for acute promyelocytic leukemia. | Leukemia research 20091001 |
Adverse events associated with common therapy regimens for moderate-to-severe Crohn's disease. | The American journal of gastroenterology 20091001 |
Glyceraldehyde 3-phosphate dehydrogenase depletion induces cell cycle arrest and resistance to antimetabolites in human carcinoma cell lines. | The Journal of pharmacology and experimental therapeutics 20091001 |
Changes in matrix metalloproteinase (MMP) and tissue inhibitors of metalloproteinases (TIMP) expression profile in Crohn's disease after immunosuppressive treatment correlate with histological score and calprotectin values. | International journal of colorectal disease 20091001 |
Dose-response relationships of rat fetal skeleton variations: Relevance for risk assessment. | Environmental research 20091001 |
The effect of active hexose correlated compound in modulating cytosine arabinoside-induced hair loss, and 6-mercaptopurine- and methotrexate-induced liver injury in rodents. | Cancer epidemiology 20091001 |
Dexamethasone-based therapy for childhood acute lymphoblastic leukaemia: results of the prospective Dutch Childhood Oncology Group (DCOG) protocol ALL-9 (1997-2004). | The Lancet. Oncology 20091001 |
Inflammatory bowel diseases and management considerations: fertility and pregnancy. | Current gastroenterology reports 20091001 |
New and emerging therapies for inflammatory bowel diseases. | Journal of gastroenterology and hepatology 20091001 |
Efficacy of methotrexate in Crohn's disease and ulcerative colitis patients unresponsive or intolerant to azathioprine /mercaptopurine. | Alimentary pharmacology & therapeutics 20090915 |
Emerging treatments for complex perianal fistula in Crohn's disease. | World journal of gastroenterology 20090914 |
Autoimmune pancreatitis with multiorgan involvement. A case of pericardial involvement. | JOP : Journal of the pancreas 20090904 |
Autologous hematopoietic stem cell transplantation in adult acute lymphoblastic leukemia: still not out of fashion. | Annals of hematology 20090901 |
Inflammatory bowel disease in the setting of autoimmune pancreatitis. | Inflammatory bowel diseases 20090901 |
On the effect of thalidomide on Mycobacterium avium subspecies paratuberculosis in culture. | International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20090901 |
The role of transporters in the pharmacokinetics of orally administered drugs. | Pharmaceutical research 20090901 |
Anaplastic large cell lymphoma of the ovary in a pediatric patient. | Journal of pediatric hematology/oncology 20090901 |
Mutagenicity and potential carcinogenicity of thiopurine treatment in patients with inflammatory bowel disease. | Cancer research 20090901 |
Long term efficacy and safety of allopurinol and azathioprine or 6-mercaptopurine in patients with inflammatory bowel disease. | Journal of Crohn's & colitis 20090901 |
Thiopurines, a previously unrecognised cause for fatigue in patients with inflammatory bowel disease. | Journal of Crohn's & colitis 20090901 |
CNS relapse in a low risk acute promyelocytic leukemia patient treated with ATRA-based regimen: is there a role for prophylactic CNS therapy in acute promyelocytic leukemia? | Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion 20090901 |
Synthesis of designed conductive one-dimensional coordination polymers of Ni(II) with 6-mercaptopurine and 6-thioguanine. | Inorganic chemistry 20090817 |
Polymorphisms in multidrug resistance-associated protein gene 4 is associated with outcome in childhood acute lymphoblastic leukemia. | Blood 20090813 |
Thiopurine methyltransferase genetics is not a major risk factor for secondary malignant neoplasms after treatment of childhood acute lymphoblastic leukemia on Berlin-Frankfurt-Münster protocols. | Blood 20090813 |
Incidence of stress fractures of the femoral shaft in women treated with bisphosphonate. | Acta orthopaedica 20090807 |
Infliximab and other immunomodulating drugs in patients with inflammatory bowel disease and the risk of serious bacterial infections. | Alimentary pharmacology & therapeutics 20090801 |
The impact of risk stratification by early bone-marrow response in childhood lymphoblastic leukaemia: results from the United Kingdom Medical Research Council trial ALL97 and ALL97/99. | British journal of haematology 20090801 |
Azathioprine and 6-mercaptopurine for the prevention of postoperative recurrence in Crohn's disease: a meta-analysis. | The American journal of gastroenterology 20090801 |
Phenylethanoid glycosides from Lantana fucata with in vitro anti-inflammatory activity. | Journal of natural products 20090801 |
Overexpression of X-linked inhibitor of apoptosis protein (XIAP) is an independent unfavorable prognostic factor in childhood de novo acute myeloid leukemia. | Journal of Korean medical science 20090801 |
Use of azathioprine and 6MP in postoperative Crohn's: changing natural history or just along for the ride? | The American journal of gastroenterology 20090801 |
Individualization of thiopurine therapy: thiopurine S-methyltransferase and beyond. | Pharmacogenomics 20090801 |
Semisynthesis and biological evaluation of abietane-type diterpenes. Revision of the structure of rosmaquinone. | Journal of natural products 20090801 |
Hydrogen bonding and stacking pi-pi interactions in solid 6-thioguanine and 6-mercaptopurine (antileukemia and antineoplastic drugs) studied by NMR-NQR double resonance spectroscopy and density functional theory. | The journal of physical chemistry. A 20090730 |
Meta-analysis: the efficacy of azathioprine and mercaptopurine in ulcerative colitis. | Alimentary pharmacology & therapeutics 20090701 |
Capillary electrophoresis determination of thiopurine methyl transferase activity in erythrocytes. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090701 |
Thiopurine methyltransferase and thiopurine metabolite testing in patients with inflammatory bowel disease who are taking thiopurine drugs. | Pharmacogenomics 20090701 |
[Prophylaxis and treatment of modified BFM-90 regimen for lymphoblastic lymphoma in children and adolescents accompanied with infection]. | Ai zheng = Aizheng = Chinese journal of cancer 20090701 |
Reactivation of bovine tuberculosis in patient treated with infliximab, Switzerland. | Emerging infectious diseases 20090701 |
TPMT*26 (208F-->L), a novel mutation detected in a Chinese. | British journal of clinical pharmacology 20090701 |
T cell lymphoproliferative disorders associated with anti-tumor necrosis factor alpha antibody therapy for ulcerative colitis: literature summary. | Journal of hematopathology 20090701 |
Sensitization of ABCG2-overexpressing cells to conventional chemotherapeutic agent by sunitinib was associated with inhibiting the function of ABCG2. | Cancer letters 20090628 |
Treating childhood acute lymphoblastic leukemia without cranial irradiation. | The New England journal of medicine 20090625 |
Prognostic significance of CD20 expression in adults with de novo precursor B-lineage acute lymphoblastic leukemia. | Blood 20090618 |
S-adenosylmethionine regulates thiopurine methyltransferase activity and decreases 6-mercaptopurine cytotoxicity in MOLT lymphoblasts. | Biochemical pharmacology 20090615 |
Methotrexate/6-mercaptopurine maintenance therapy influences the risk of a second malignant neoplasm after childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study. | Blood 20090611 |
On the malignant potential of thiopurine therapy. | Blood 20090611 |
Therapeutic strategies for the management of ulcerative colitis. | Inflammatory bowel diseases 20090601 |
Effective treatment of advanced-stage childhood lymphoblastic lymphoma without prophylactic cranial irradiation: results of St Jude NHL13 study. | Leukemia 20090601 |
Monitoring of thiopurine metabolites in patients with inflammatory bowel disease-what is actually measured? | Therapeutic drug monitoring 20090601 |
Fatal disseminated cytomegalovirus infection associated with infliximab and 6-mercaptopurine therapy in a child with Crohn disease. | The Pediatric infectious disease journal 20090601 |
Current and future treatments of autoimmune hepatitis. | Expert review of gastroenterology & hepatology 20090601 |
Acquired acute myelogenous leukemia after therapy for acute promyelocytic leukemia with t(15;17): a case report and review of the literature. | Puerto Rico health sciences journal 20090601 |
Serendipity-methotrexate and 6-mercaptopurine for continuation therapy for patients with acute lymphoblastic leukemia: the leukemic stem cell and beyond? | Journal of pediatric hematology/oncology 20090601 |
Oral methotrexate/6-mercaptopurine may be superior to a multidrug LSA2L2 Maintenance therapy for higher risk childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study. | Journal of pediatric hematology/oncology 20090601 |
Management of eosinophilic granuloma occurring in the appendicular skeleton in children. | Clinics in orthopedic surgery 20090601 |
Safe 6-thioguanine therapy of a TPMT deficient Crohn's disease patient by using therapeutic drug monitoring. | Journal of Crohn's & colitis 20090601 |
Influenza vaccinations: should they really be encouraged for IBD patients being treated with immunosuppressives? | Inflammatory bowel diseases 20090501 |
Heterozygosity at the TPMT gene locus, augmented by mutated MTHFR gene, predisposes to 6-MP related toxicities in childhood ALL patients. | Leukemia 20090501 |
Simultaneous analysis of plasma thiols by high-performance liquid chromatography with fluorescence detection using a new probe, 1,3,5,7-tetramethyl-8-phenyl-(4-iodoacetamido)difluoroboradiaza-s-indacene. | Journal of chromatography. A 20090501 |
Methotrexate treatment in pediatric Crohn disease patients intolerant or resistant to purine analogues. | Journal of pediatric gastroenterology and nutrition 20090501 |
Febuxostat: a new treatment for hyperuricaemia in gout. | Rheumatology (Oxford, England) 20090501 |
The presentation of 6-mercaptopurine overdose in ED. | The American journal of emergency medicine 20090501 |
Chemotherapy induced esophageal stricture. | Pediatric blood & cancer 20090401 |
Roles of inner blood-retinal barrier organic anion transporter 3 in the vitreous/retina-to-blood efflux transport of p-aminohippuric acid, benzylpenicillin, and 6-mercaptopurine. | The Journal of pharmacology and experimental therapeutics 20090401 |
Application of new resin gels for measuring mercury by diffusive gradients in a thin-films technique. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20090401 |
Inflammatory bowel disease potpourri: a vignette-based discussion. | Medicine and health, Rhode Island 20090401 |
Reproductive issues in inflammatory bowel disease. | Medicine and health, Rhode Island 20090401 |
Hepatosplenic T-cell lymphoma following infliximab therapy for Crohn's disease. | The Medical journal of Australia 20090316 |
Mercaptopurine treatment should be considered in azathioprine intolerant patients with inflammatory bowel disease. | Alimentary pharmacology & therapeutics 20090315 |
6-Thioguanine therapy in Crohn's disease--observational data in Swedish patients. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20090301 |
Early preservation of effector functions followed by eventual T cell memory depletion: a model for the delayed onset of the effect of thiopurines. | Gut 20090301 |
Thiopurine methyltransferase activity is related to the risk of relapse of childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study. | Leukemia 20090301 |
Efficacy of infliximab in pediatric Crohn's disease: a randomized multicenter open-label trial comparing scheduled to on demand maintenance therapy. | Inflammatory bowel diseases 20090301 |
Distribution of TPMT risk alleles for thiopurine [correction of thioupurine] toxicity in the Israeli population. | European journal of clinical pharmacology 20090301 |
Systematic review: does concurrent therapy with 5-ASA and immunomodulators in inflammatory bowel disease improve outcomes? | Alimentary pharmacology & therapeutics 20090301 |
Time-course changes in neural cell apoptosis in the rat fetal brain from dams treated with 6-mercaptopurine (6-MP). | Histology and histopathology 20090301 |
[Pharmacological and pharmacogenetic study of two immunomodulators: azathioprine and 6-mercaptopurine. Strategies for preventing complications]. | Gastroenterologie clinique et biologique 20090301 |
Where are all the Mycobacterium avium subspecies paratuberculosis in patients with Crohn's disease? | PLoS pathogens 20090301 |
Medical therapy of IBD in 2009. | Medicine and health, Rhode Island 20090301 |
3-Alkylpyridinium alkaloids from the Pacific sponge Haliclona sp. | Journal of natural products 20090227 |
Development and validation of an HPLC method for the rapid and simultaneous determination of 6-mercaptopurine and four of its metabolites in plasma and red blood cells. | Journal of pharmaceutical and biomedical analysis 20090220 |
Pharmacogenetics--tailoring treatment for the outliers. | The New England journal of medicine 20090219 |
Novel derivatives of 6-mercaptopurine: synthesis, characterization and antiproliferative activities of S-allylthio-mercaptopurines. | European journal of medicinal chemistry 20090201 |
Genetic polymorphism of inosine triphosphate pyrophosphatase is a determinant of mercaptopurine metabolism and toxicity during treatment for acute lymphoblastic leukemia. | Clinical pharmacology and therapeutics 20090201 |
Co-prescribing azathiopurine or 6-mercaptopurine and 5-aminosalicylate compounds in ulcerative colitis. | Inflammatory bowel diseases 20090201 |
6-mercaptopurine as an alternative to azathioprine in azathioprine-induced hepatoxicity. | Inflammatory bowel diseases 20090201 |
The increasing complexity of mercaptopurine pharmacogenomics. | Clinical pharmacology and therapeutics 20090201 |
[Optimising azathioprine treatment: determination of thiopurine methyltransferase activity and thiopurine metabolites]. | Anales de pediatria (Barcelona, Spain : 2003) 20090201 |
Normal thiopurine methyltransferase phenotype testing in a Crohn disease patient with azathioprine induced myelosuppression. | Internal medicine journal 20090201 |
A new method for CE-EC determination of mercaptopurine (MP) in a PMMA biochip with on-chip gold nano-electrode ensemble (GNEE) working and decouple electrodes. | Journal of nanoscience and nanotechnology 20090201 |
[Thiopurine S-methyltransferase gene polymorphism in Chilean blood donors]. | Revista medica de Chile 20090201 |
[Treatment of Crohn's disease]. | Praxis 20090121 |
Azathioprine or 6-mercaptopurine for maintenance of remission in Crohn's disease. | The Cochrane database of systematic reviews 20090121 |
Response to mercaptopurine for refractory autoimmune cytopenias in children. | Pediatric blood & cancer 20090101 |
Foot-drop: an unusual complaint in Henoch-Schönlein purpura. | Pediatric nephrology (Berlin, Germany) 20090101 |
6-Mercaptopurine: teaching an old drug new tricks. | Pediatric blood & cancer 20090101 |
Langerhans cell histiocytosis in children. | Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses 20090101 |
6-Mercaptopurine (6-MP) induces cell cycle arrest and apoptosis of neural progenitor cells in the developing fetal rat brain. | Neurotoxicology and teratology 20090101 |
Targeting of cancer energy metabolism. | Molecular nutrition & food research 20090101 |
Poor treatment compliance in children with down syndrome and acute lymphoblastic leukemia. | Journal of pediatric hematology/oncology 20090101 |
Pharmacogenetics and pharmacogenomics of anticancer agents. | CA: a cancer journal for clinicians 20090101 |
Current strategies for the treatment of ulcerative colitis. | Recent patents on inflammation & allergy drug discovery 20090101 |
Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration. | Arthritis research & therapy 20090101 |
Thiopurine S-methyltransferase and inosine triphosphate pyrophosphohydrolase genes in Japanese patients with inflammatory bowel disease in whom adverse drug reactions were induced by azathioprine/6-mercaptopurine treatment. | Journal of gastroenterology 20090101 |
ALK-positive diffuse large B-cell lymphoma: report of four cases and review of the literature. | Journal of hematology & oncology 20090101 |
Thiopurine methyltransferase gene polymorphisms in Chinese patients with inflammatory bowel disease. | Digestion 20090101 |
6-mercaptopurine (6-MP) induces p53-mediated apoptosis of neural progenitor cells in the developing fetal rodent brain. | Neurotoxicology and teratology 20090101 |
Interferon beta-1a for the maintenance of remission in patients with Crohn's disease: results of a phase II dose-finding study. | BMC gastroenterology 20090101 |
Monensin causes dose dependent inhibition of Mycobacterium avium subspecies paratuberculosis in radiometric culture. | Gut pathogens 20090101 |
Hypersensitivity reactions to antineoplastic agents: an overview. | Anti-cancer drugs 20090101 |
Thiopurine analogue inhibitors of severe acute respiratory syndrome-coronavirus papain-like protease, a deubiquitinating and deISGylating enzyme. | Antiviral chemistry & chemotherapy 20090101 |
Leukopenia due to parvovirus B19 in a Crohn's disease patient using azathioprine. | Digestion 20090101 |
Severe myelosuppression following alopecia shortly after the initiation of 6-mercaptopurine in a patient with Crohn's disease. | Internal medicine (Tokyo, Japan) 20090101 |
Azathioprine favourably influences the course of malaria. | Malaria journal 20090101 |
Selective killing of tumors deficient in methylthioadenosine phosphorylase: a novel strategy. | PloS one 20090101 |
Gold nanoparticles induce cytotoxicity in the alveolar type-II cell lines A549 and NCIH441. | Particle and fibre toxicology 20090101 |
Allele frequency of thiopurine methyltransferase and inosine triphosphate pyrophosphatase gene polymorphisms in Korean patients with inflammatory bowel diseases. | Hepato-gastroenterology 20090101 |
Mycobacterium avium subspecies paratuberculosis, Crohn's disease and the Doomsday scenario. | Gut pathogens 20090101 |
Epstein-Barr Virus (EBV) Prevalence and the Risk of Reactivation in Patients with Inflammatory Arthritis Using Anti-TNF Agents and in those who are Biologic Naive. | The open rheumatology journal 20090101 |
Gout. Novel therapies for treatment of gout and hyperuricemia. | Arthritis research & therapy 20090101 |
Management strategies for pulmonary sarcoidosis. | Therapeutics and clinical risk management 20090101 |
Biologic targeting in the treatment of inflammatory bowel diseases. | Biologics : targets & therapy 20090101 |
Genome-wide analysis of small RNA and novel MicroRNA discovery in human acute lymphoblastic leukemia based on extensive sequencing approach. | PloS one 20090101 |
[P-glycoprotein functional activity in peripheral blood lymphocytes in ulcerative colitis]. | Medicina 20090101 |
Mild to moderate Crohn's disease: still room for step-up therapies? | Digestive diseases (Basel, Switzerland) 20090101 |
Drug monitoring in inflammatory bowel disease: helpful or dispensable? | Digestive diseases (Basel, Switzerland) 20090101 |
Drugs associated with more suicidal ideations are also associated with more suicide attempts. | PloS one 20090101 |
Detailed analysis of X chromosome inactivation in a 49,XXXXX pentasomy. | Molecular cytogenetics 20090101 |
Medical management of ulcerative colitis. | Digestive diseases (Basel, Switzerland) 20090101 |
The future of inflammatory bowel disease care. | Reviews in gastroenterological disorders 20090101 |
Current trends in the management of ocular symptoms in Adamantiades-Behçet's disease. | Clinical ophthalmology (Auckland, N.Z.) 20090101 |
Simultaneous occurrence of hyperthyroidism and fistulizing Crohn's disease complicated with intra-abdominal fistulas and abscess: a case report and review of the literature. | Cases journal 20090101 |
Recurrent orbital myositis with radiological feature mimicking thyroid eye disease in a patient with Crohn's disease. | Orbit (Amsterdam, Netherlands) 20090101 |
Patient considerations in the management of ulcerative colitis: role of once-daily MMX mesalamine. | Patient preference and adherence 20090101 |
The efficacy of low dose azathioprine/6-mercaptopurine in patients with inflammatory bowel disease. | Hepato-gastroenterology 20090101 |
Vitamin e and N-acetylcysteine as antioxidant adjuvant therapy in children with acute lymphoblastic leukemia. | Advances in hematology 20090101 |
A systematic review of the reporting of Data Monitoring Committees' roles, interim analysis and early termination in pediatric clinical trials. | BMC pediatrics 20090101 |
An evidence-based review of natalizumab therapy in the management of Crohn's disease. | Therapeutics and clinical risk management 20090101 |
TPMT and DPD polymorphisms: Efficient screening method for Indian patients considering taking Thiopurine and 5-FU drugs. | Disease markers 20090101 |
Genetic variations in the HGPRT, ITPA, IMPDH1, IMPDH2, and GMPS genes in Japanese individuals. | Drug metabolism and pharmacokinetics 20090101 |
Mizoribine: a new approach in the treatment of renal disease. | Clinical & developmental immunology 20090101 |
Development of fludarabine formulations in the treatment of chronic lymphocytic leukemia. | Drug design, development and therapy 20090101 |
Changing therapy from Glivecto a 'copy' imatinib results in a worsening of chronic myeloid leukemia disease status: two case reports. | Cases journal 20090101 |
Hand-foot syndrome due to capecitabine. | Indian journal of dermatology 20090101 |
Molecular dynamics simulation of a human thiopurine S-methyltransferase complexed with 6-mercaptopurine model. | Bioinformation 20090101 |
The rise of an opportunistic infection called 'Invasive Zygomycosis'. | Journal of global infectious diseases 20090101 |
Clinician adoption of genetic testing for drug metabolizing enzymes: is patient safety the low-hanging fruit of personalized medicine? | AMIA ... Annual Symposium proceedings. AMIA Symposium 20090101 |
[Phytocorrection of structural changes in the gastrointestinal tract caused by 6-mercaptopurine]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20090101 |
Polyelectrolyte Complexes: A Review of their Applicability in Drug Delivery Technology. | Indian journal of pharmaceutical sciences 20090101 |
Does infliximab increase complications after surgery for inflammatory bowel disease? | F1000 medicine reports 20090101 |
Extraction of Conditional Probabilities of the Relationships Between Drugs, Diseases, and Genes from PubMed Guided by Relationships in PharmGKB. | Summit on translational bioinformatics 20090101 |
Cause for controversy? Infliximab in the treatment of ulcerative colitis: an update. | Clinical and experimental gastroenterology 20090101 |
Pharmacogenetics: implementing personalized medicine. | Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases 20090101 |
Initial clinical experience with allopurinol-thiopurine combination therapy in pediatric inflammatory bowel disease. | Inflammatory bowel diseases 20081201 |
Minimal residual disease is an important predictive factor of outcome in children with relapsed 'high-risk' acute lymphoblastic leukemia. | Leukemia 20081201 |
Cost-effectiveness of 5-aminosalicylic acid therapy for maintenance of remission in ulcerative colitis. | The American journal of gastroenterology 20081201 |
Population pharmacokinetic and pharmacogenetic analysis of 6-mercaptopurine in paediatric patients with acute lymphoblastic leukaemia. | British journal of clinical pharmacology 20081201 |
Severe hepatotoxicity with high 6-methylmercaptopurine nucleotide concentrations after thiopurine dose escalation due to low 6-thioguanine nucleotides. | European journal of gastroenterology & hepatology 20081201 |
Optimizing conventional therapy for inflammatory bowel disease. | Current gastroenterology reports 20081201 |
Thiopurine S-methyltransferase (TPMT) gene polymorphism in Brazilian children with acute lymphoblastic leukemia: association with clinical and laboratory data. | Therapeutic drug monitoring 20081201 |
Analysis of germline GLI1 variation implicates hedgehog signalling in the regulation of intestinal inflammatory pathways. | PLoS medicine 20081201 |
[Efficacy of premedication with intravenous corticosteroids and antihistaminics in preventing infusion reactions to infliximab]. | Gastroenterologia y hepatologia 20081201 |
[Inflammatory bowel disease. If a patient with Crohn's disease remains in remission for 4 years with azathioprine (or mercaptopurine), should the drug be withdrawn?]. | Gastroenterologia y hepatologia 20081201 |
Adalimumab for the treatment of Crohn's disease. | Biologics : targets & therapy 20081201 |
Lower doses of 6-mercaptopurine/azathioprine bring enough clinical efficacy and therapeutic concentration of erythrocyte 6-mercaptopurine metabolite in Japanese IBD patients. | Journal of Crohn's & colitis 20081201 |
Azathioprine treatment during lactation. | Alimentary pharmacology & therapeutics 20081115 |
Genome-wide copy number profiling reveals molecular evolution from diagnosis to relapse in childhood acute lymphoblastic leukemia. | Blood 20081115 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. | Journal of medicinal chemistry 20081113 |
A lecithinized superoxide dismutase (PC-SOD) improves ulcerative colitis. | Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20081101 |
Influence of methylene tetrahydrofolate reductase polymorphisms and coadministration of antimetabolites on toxicity after high dose methotrexate. | European journal of haematology 20081101 |
Oral mucositis in acute lymphoblastic leukaemia: analysis of 169 paediatric patients. | Oral diseases 20081101 |
Maintenance therapy with dose-adjusted 6-mercaptopurine in idiopathic pulmonary hemosiderosis. | Pediatric pulmonology 20081101 |
Pharmacodynamic parameters of immunosuppressive drugs are not correlated with age, duration of dialysis, percentage of lymphocytes or lymphocyte stimulation index in renal transplant recipients. | Biological & pharmaceutical bulletin 20081101 |
2-Arylbenzimidazoles as antiviral and antiproliferative agents. Part 1. | Medicinal chemistry (Shariqah (United Arab Emirates)) 20081101 |
Genetic analysis of human traits in vitro: drug response and gene expression in lymphoblastoid cell lines. | PLoS genetics 20081101 |
PTCH mutations in basal cell carcinomas from azathioprine-treated organ transplant recipients. | British journal of cancer 20081021 |
The effect of thiopurine drugs on DNA methylation in relation to TPMT expression. | Biochemical pharmacology 20081015 |
Results of the hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone regimen in elderly patients with acute lymphocytic leukemia. | Cancer 20081015 |
Pharmacogenomic studies of the anticancer and immunosuppressive thiopurines mercaptopurine and azathioprine. | British journal of clinical pharmacology 20081001 |
Laboratory evaluation of inflammatory bowel disease. | Current opinion in pediatrics 20081001 |
What are the rules when treatment with 6-MP/AZA is started? | Inflammatory bowel diseases 20081001 |
Is it always therapeutically important to distinguish between Crohn's disease and ulcerative colitis? | Inflammatory bowel diseases 20081001 |
Neo-clinicians, clinical trials, and the reorganization of medical research in Paris hospitals after the Second World War: the trajectory of Jean Bernard. | Medical history 20081001 |
Treatment of Crohn's disease with colony-stimulating factors: An overview. | Therapeutics and clinical risk management 20081001 |
Complete regression of cirrhosis after immunosuppressive treatment in autoimmune hepatitis. | Pediatrics international : official journal of the Japan Pediatric Society 20081001 |
Miscellaneous. | Indian journal of pharmacology 20081001 |
Crohnology: a tale of time and times and inflammatory bowel diseases. | World journal of gastroenterology 20080928 |
Are we giving azathioprine too late? The case for early immunomodulation in inflammatory bowel disease. | World journal of gastroenterology 20080928 |
Review article: treatment algorithms to maximize remission and minimize corticosteroid dependence in patients with inflammatory bowel disease. | Alimentary pharmacology & therapeutics 20080915 |
Influence of xanthine oxidase on thiopurine metabolism in Crohn's disease. | Alimentary pharmacology & therapeutics 20080915 |
Long-term outcome of using allopurinol co-therapy as a strategy for overcoming thiopurine hepatotoxicity in treating inflammatory bowel disease. | Alimentary pharmacology & therapeutics 20080915 |
Medication adherence and quality of life in pediatric inflammatory bowel disease. | Journal of pediatric psychology 20080901 |
Efficacy of infliximab for induction and maintenance of remission in intestinal Behçet's disease. | Inflammatory bowel diseases 20080901 |
Predictive factors associated with immunosuppressive agent use in ulcerative colitis: a case-control study. | Alimentary pharmacology & therapeutics 20080901 |
Monitoring 6-thioguanine nucleotide concentrations in Japanese patients with inflammatory bowel disease. | Journal of gastroenterology and hepatology 20080901 |
Thiopurine hepatotoxicity in inflammatory bowel disease: the role for adding allopurinol. | Expert opinion on drug safety 20080901 |
Contribution of the drug transporter ABCG2 (breast cancer resistance protein) to resistance against anticancer nucleosides. | Molecular cancer therapeutics 20080901 |
[Benefits and risks of immunosuppression in chronic inflammatory bowel diseases]. | Deutsche medizinische Wochenschrift (1946) 20080901 |
Azathioprine: when less is more. | Journal of gastroenterology and hepatology 20080901 |
Gene polymorphisms and pharmacogenetics in rheumatoid arthritis. | Current genomics 20080901 |
Colon-targeted delivery of live bacterial cell biotherapeutics including microencapsulated live bacterial cells. | Biologics : targets & therapy 20080901 |
Infliximab in ulcerative colitis. | Biologics : targets & therapy 20080901 |
Mutagenic and cytotoxic properties of 6-thioguanine, S6-methylthioguanine, and guanine-S6-sulfonic acid. | The Journal of biological chemistry 20080829 |
The study of oxidization fluorescence sensor with molecular imprinting polymer and its application for 6-mercaptopurine (6-MP) determination. | Talanta 20080815 |
On the rate and extent of drug delivery to the brain. | Pharmaceutical research 20080801 |
Clinical pharmacology and pharmacogenetics of thiopurines. | European journal of clinical pharmacology 20080801 |
Pure motor lumbosacral radiculopathy after intrathecal chemotherapy. | European journal of neurology 20080801 |
A video game improves behavioral outcomes in adolescents and young adults with cancer: a randomized trial. | Pediatrics 20080801 |
Palmar-plantar erythrodysesthesia caused by mercaptopurine and mesalamine. | Archives of dermatology 20080801 |
Immune reconstitution during maintenance therapy in children with acute lymphoblastic leukemia, relation to co-existing infection. | Hematology (Amsterdam, Netherlands) 20080801 |
Efficacy of 6-mercaptopurine treatment after azathioprine hypersensitivity in inflammatory bowel disease. | World journal of gastroenterology 20080721 |
Renal cell carcinoma in a patient with cystinosis and inflammatory bowel disease: a case report. | Pediatric nephrology (Berlin, Germany) 20080701 |
Decrease in factor V activity: a new adverse effect of purine analogs in inflammatory bowel diseases? | Inflammatory bowel diseases 20080701 |
Effect of early immunomodulator use in moderate to severe pediatric Crohn disease. | Inflammatory bowel diseases 20080701 |
The role of maintenance chemotherapy after autotransplantation for acute lymphoblastic leukemia in first remission: single-center experience of 100 patients. | Bone marrow transplantation 20080701 |
Azathioprine-induced warfarin resistance. | The Annals of pharmacotherapy 20080701 |
Thiopurine-induced myelotoxicity in patients with inflammatory bowel disease: a review. | The American journal of gastroenterology 20080701 |
Transporter-mediated protection against thiopurine-induced hematopoietic toxicity. | Cancer research 20080701 |
Effects and treatment of inflammatory bowel disease during pregnancy. | Canadian family physician Medecin de famille canadien 20080701 |
Severe neurotoxicities in a case of Charcot-Marie-Tooth disease type 2 caused by vincristine for acute lymphoblastic leukemia. | Journal of pediatric hematology/oncology 20080701 |
Use of allopurinol to optimize thiopurine immunomodulator efficacy in inflammatory bowel disease. | Gastroenterology & hepatology 20080701 |
Down-regulation of Na+/H+ exchanger regulatory factor 1 increases expression and function of multidrug resistance protein 4. | Cancer research 20080615 |
Structural basis of substrate recognition in thiopurine s-methyltransferase. | Biochemistry 20080610 |
Exposing the weaknesses: a systematic review of azathioprine efficacy in ulcerative colitis. | Digestive diseases and sciences 20080601 |
Increased dosing requirements for 6-mercaptopurine and azathioprine in inflammatory bowel disease patients six years and younger. | Inflammatory bowel diseases 20080601 |
Use of methotrexate in refractory Crohn's disease: the Edinburgh experience. | Inflammatory bowel diseases 20080601 |
Thiopurine methyltransferase activity combined with 6-thioguanine metabolite levels predicts clinical response to thiopurines in patients with inflammatory bowel disease. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20080601 |
A purine-selective nucleobase/nucleoside transporter in PK15NTD cells. | American journal of physiology. Regulatory, integrative and comparative physiology 20080601 |
Withdrawal of immunosuppression in Crohn's disease treated with scheduled infliximab maintenance: a randomized trial. | Gastroenterology 20080601 |
Antiproliferative oleanane saponins from Meryta denhamii. | Journal of natural products 20080601 |
Modulatory effects of 6-carboxymethylthiopurine on activated murine macrophages. | Chemical biology & drug design 20080601 |
Thiopurine dose in intermediate and normal metabolizers of thiopurine methyltransferase may differ three-fold. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20080601 |
Fatal myelotoxicity after azathioprine treatment. | Nucleosides, nucleotides & nucleic acids 20080601 |
Effect of 6-mercaptopurine on rat placenta. | The Journal of veterinary medical science 20080601 |
Natalizumab in the treatment of Crohn's disease. | Biologics : targets & therapy 20080601 |
Cytotoxic activities of nucleoside and nucleobase analog drugs in malignant mesothelioma: characterization of a novel nucleobase transport activity. | Biochemical pharmacology 20080515 |
A novel gene delivery system for stable transfection of thiopurine-S-methyltransferase gene in versatile cell types. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080501 |
Up-regulation of MRP4 and down-regulation of influx transporters in human leukemic cells with acquired resistance to 6-mercaptopurine. | Leukemia research 20080501 |
6-mercaptopurine and 9-(2-phosphonyl-methoxyethyl) adenine (PMEA) transport altered by two missense mutations in the drug transporter gene ABCC4. | Human mutation 20080501 |
Infliximab-induced disseminated histoplasmosis in a patient with Crohn's disease. | Nature clinical practice. Gastroenterology & hepatology 20080501 |
[Effectiveness of maintenance azathioprine therapy without oral cyclosporine after severe attacks of ulcerative colitis refractory to endovenous steroids]. | Gastroenterologia y hepatologia 20080501 |
Influence of MTHFR and RFC1 polymorphisms on toxicities during maintenance chemotherapy for childhood acute lymphoblastic leukemia or lymphoma. | Journal of pediatric hematology/oncology 20080501 |
[Immunomodulator therapy for maintenance of remission in Crohn's disease]. | Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20080501 |
Successful treatment of adult multisystemic Langerhans cell histiocytosis with psoralen-UV-A, prednisolone, mercaptopurine, and vinblastine. | Archives of dermatology 20080501 |
[The frequency and the course of the adverse effects of azathioprine/6-mercaptopurine treatment in patients with inflammatory bowel disease]. | The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20080501 |
[The frequency and the course of the adverse effects of azathioprine/6-mercaptopurine treatment in patients with inflammatory bowel disease]. | The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20080501 |
[Chemiluminescence determination of 6-mercaptopurine in the luminol-potassium ferricyanide system]. | Guang pu xue yu guang pu fen xi = Guang pu 20080501 |
Glutathione transferase activity with a novel substrate mimics the activation of the prodrug azathioprine. | Analytical biochemistry 20080415 |
Thiopurine analogues inhibit papain-like protease of severe acute respiratory syndrome coronavirus. | Biochemical pharmacology 20080415 |
[Epstein-Barr virus-associated large B-cell lymphoma in a patient with colitis ulcerosa treated with azathioprine]. | Ugeskrift for laeger 20080407 |
How are Azathioprine and 6-mercaptopurine dosed by gastroenterologists? Results of a survey of clinical practice. | Inflammatory bowel diseases 20080401 |
IgA nephropathy associated with leukemia and lymphoma: report of two cases. | Clinical and experimental nephrology 20080401 |
Differential toxic effects of azathioprine, 6-mercaptopurine and 6-thioguanine on human hepatocytes. | Toxicology in vitro : an international journal published in association with BIBRA 20080401 |
A case of adult Langerhans cell histiocytosis showing successfully regenerated osseous tissue of the skull after chemotherapy. | International journal of hematology 20080401 |
Effect of frequently used chemotherapeutic drugs on cytotoxic activity of human cytotoxic T-lymphocytes. | Journal of immunotherapy (Hagerstown, Md. : 1997) 20080401 |
In vivo immunomodulatory, cumulative skin irritation, sensitization and effect of d-limonene on permeation of 6-mercaptopurine through transdermal drug delivery. | Biological & pharmaceutical bulletin 20080401 |
In vivo response to methotrexate forecasts outcome of acute lymphoblastic leukemia and has a distinct gene expression profile. | PLoS medicine 20080401 |
Acute diarrhea during azathioprine treatment of type I autoimmune hepatitis. | Minerva medica 20080401 |
Outcomes of a modified CALGB 19802 regimen in adult acute lymphoblastic leukemia. | Journal of Korean medical science 20080401 |
Treating refractory leukemias in childhood, role of clofarabine. | Therapeutics and clinical risk management 20080401 |
Parotid acinar cell carcinoma in a long-term survivor of childhood acute lymphoblastic leukemia. | Pediatric blood & cancer 20080301 |
Thyroid involvement with Langerhans cell histiocytosis in a 3-year-old male. | Pediatric blood & cancer 20080301 |
EBV+ lymphoproliferative disease following prolonged chemotherapy for refractory LCH. | Pediatric blood & cancer 20080301 |
Fatal adenovirus hepatitis during maintenance therapy for childhood acute lymphoblastic leukemia. | Pediatric blood & cancer 20080301 |
Triple intrathecal therapy without cranial irradiation for central nervous system preventive therapy in childhood acute lymphoblastic leukemia. | Pediatric blood & cancer 20080301 |
Squamous dysplasia of the rectum in a patient with ulcerative colitis treated with 6-mercaptopurine. | Digestive diseases and sciences 20080301 |
Improved outcome in multisystem Langerhans cell histiocytosis is associated with therapy intensification. | Blood 20080301 |
Effect of buffer and antioxidant on stability of a mercaptopurine suspension. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080301 |
Ethnic variation of thiopurine S-methyltransferase activity: a large, prospective population study. | Pharmacogenomics 20080301 |
Rituximab therapy for refractory biliary strictures in immunoglobulin G4-associated cholangitis. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20080301 |
The impact of medical therapy for inflammatory bowel disease on pregnancy outcome. | The American journal of gastroenterology 20080301 |
Tubulointerstitial nephritis: an extraintestinal manifestation of Crohn disease in children. | Journal of pediatric gastroenterology and nutrition 20080301 |
Pitfalls, prevention, and treatment of hyperuricemia during tumor lysis syndrome in the era of rasburicase (recombinant urate oxidase). | Biologics : targets & therapy 20080301 |
The Role of heat shock protein 27 in extravillous trophoblast differentiation. | Journal of cellular biochemistry 20080215 |
Treatment of neurodegenerative CNS disease in Langerhans cell histiocytosis with a combination of intravenous immunoglobulin and chemotherapy. | Pediatric blood & cancer 20080201 |
Tolerability and safety of mercaptopurine in azathioprine-intolerant patients with inflammatory bowel disease. | Alimentary pharmacology & therapeutics 20080201 |
Absence of nodular regenerative hyperplasia after low-dose 6-thioguanine maintenance therapy in inflammatory bowel disease patients. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20080201 |
Structural determinants of glutathione transferases with azathioprine activity identified by DNA shuffling of alpha class members. | Journal of molecular biology 20080201 |
Synthesis and cytotoxic activity of imidazo[1,2-a]-1,3,5-triazine analogues of 6-mercaptopurine. | Archiv der Pharmazie 20080201 |
Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment. | European journal of clinical pharmacology 20080201 |
Use of allopurinol with low-dose 6-mercaptopurine in inflammatory bowel disease to achieve optimal active metabolite levels: a review of four cases and the literature. | Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20080201 |
Isolated central nervous system relapse in childhood acute promyelocytic leukemia. | Journal of pediatric hematology/oncology 20080201 |
Start low, go slow, but don't go this way yet. | Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20080201 |
Azathioprine in inflammatory bowel disease: improved molecular insights and resulting clinical implications. | Expert review of gastroenterology & hepatology 20080201 |
Treatment of inflammatory bowel disease: a review of medical therapy. | World journal of gastroenterology 20080121 |
Gold nanoparticles enhance the anti-leukemia action of a 6-mercaptopurine chemotherapeutic agent. | Langmuir : the ACS journal of surfaces and colloids 20080115 |
Long-term results of the AIEOP-ALL-95 Trial for Childhood Acute Lymphoblastic Leukemia: insight on the prognostic value of DNA index in the framework of Berlin-Frankfurt-Muenster based chemotherapy. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080110 |
IMPDH activity in thiopurine-treated patients with inflammatory bowel disease - relation to TPMT activity and metabolite concentrations. | British journal of clinical pharmacology 20080101 |
Azathioprine-associated acute myeloid leukemia in a patient with Crohn's disease and thiopurine S-methyltransferase deficiency. | American journal of hematology 20080101 |
High mobility group protein B1 is an activator of apoptotic response to antimetabolite drugs. | Molecular pharmacology 20080101 |
Health care and cost of medication for inflammatory bowel disease in the Rhein-Main region, Germany: a multicenter, prospective, internet-based study. | Inflammatory bowel diseases 20080101 |
Disparities in the use of immunomodulators and biologics for the treatment of inflammatory bowel disease: a retrospective cohort study. | Inflammatory bowel diseases 20080101 |
Thiopurines in current medical practice: molecular mechanisms and contributions to therapy-related cancer. | Nature reviews. Cancer 20080101 |
Stability of thiopurine metabolites: a potential analytical bias. | Clinical chemistry 20080101 |
Ondansetron-associated hypokalemia in a 2-year-old with pre-B-cell ALL. | Journal of pediatric hematology/oncology 20080101 |
Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells. | Molecular cancer 20080101 |
Protocol for the combined immunosuppression & radiotherapy in thyroid eye disease (CIRTED) trial: a multi-centre, double-masked, factorial randomised controlled trial. | Trials 20080101 |
Wound healing in patients with cancer. | Eplasty 20080101 |
Pulmonary manifestations in a pediatric patient with ulcerative colitis: a case report. | Journal of medical case reports 20080101 |
Pharmacogenomics of drug-metabolizing enzymes and drug transporters in chemotherapy. | Methods in molecular biology (Clifton, N.J.) 20080101 |
Pharmacogenomics in gastrointestinal disorders. | Methods in molecular biology (Clifton, N.J.) 20080101 |
Histopathology of liver biopsies from a thiopurine-naïve inflammatory bowel disease cohort: prevalence of nodular regenerative hyperplasia. | Scandinavian journal of gastroenterology 20080101 |
Proteomic changes in rat hippocampus and adrenals following short-term sleep deprivation. | Proteome science 20080101 |
The binding of the sulfur and oxygen purine derivatives with bovine serum albumin. | Acta poloniae pharmaceutica 20080101 |
The usefulness of growth hormone treatment for psychological status in young adult survivors of childhood leukaemia: an open-label study. | BMC pediatrics 20080101 |
On the action of cyclosporine A, rapamycin and tacrolimus on M. avium including subspecies paratuberculosis. | PloS one 20080101 |
Efficacy and safety of azathioprine and 6-mercaptopurine in Japanese pediatric patients with ulcerative colitis: a survey of the Japanese Society for Pediatric Inflammatory Bowel Disease. | Digestion 20080101 |
Reactivation of hepatitis B in a patient with Crohn's disease treated using infliximab. | Journal of gastroenterology 20080101 |
Improved outcome for children with acute lymphoblastic leukemia after risk-adjusted intensive therapy: a single-institution experience. | Annals of Saudi medicine 20080101 |
On the prevalence of M. avium subspecies paratuberculosis DNA in the blood of healthy individuals and patients with inflammatory bowel disease. | PloS one 20080101 |
Membranous glomerulopathy associated with rheumatoid arthritis may respond to rituximab. | Scandinavian journal of rheumatology 20080101 |
Sinusoidal obstruction syndrome (veno-occlusive disease) in a patient receiving bevacizumab for metastatic colorectal cancer: a case report. | Journal of medical case reports 20080101 |
Prognostic impact of combined fludarabine, treosulfan and mitoxantrone resistance profile in childhood acute myeloid leukemia. | Anticancer research 20080101 |
Cell killing and resistance in pre-operative breast cancer chemotherapy. | BMC cancer 20080101 |
Laparoscopic ileocolic resection versus infliximab treatment of distal ileitis in Crohn's disease: a randomized multicenter trial (LIR!C-trial). | BMC surgery 20080101 |
[6-mercaptopurine-related hand-foot syndrome in a four-year-old child]. | Annales de dermatologie et de venereologie 20080101 |
Myeloid dendritic cells display downregulation of C-type lectin receptors and aberrant lectin uptake in systemic lupus erythematosus. | Arthritis research & therapy 20080101 |
Combining gene expression, demographic and clinical data in modeling disease: a case study of bipolar disorder and schizophrenia. | BMC genomics 20080101 |
Effect of dexamethasone on quality of life in children with acute lymphoblastic leukaemia: a prospective observational study. | Health and quality of life outcomes 20080101 |
Undue reliance on I(2) in assessing heterogeneity may mislead. | BMC medical research methodology 20080101 |
Treatment of acute lymphoblastic leukemia in children and adolescents: peaks and pitfalls. | Hematology. American Society of Hematology. Education Program 20080101 |
[Adolescents with de novo acute lymphoblastic leukemia: efficacy and safety of a pediatric vs adult treatment protocol]. | Gaceta medica de Mexico 20080101 |
Eosinophilic oesophagitis: clinical manifestations and treatment options. The role of the allergologist. | Allergologia et immunopathologia 20080101 |
[Importance of genotyping of thiopurine S-methyltransferase in children with acute lymphoblastic leukaemia during maintenance therapy]. | Srpski arhiv za celokupno lekarstvo 20080101 |
Effects of 5-fluorouracil on human mitogen-activated peripheral blood lymphocytes from healthy individuals. | Anticancer research 20080101 |
Sensitive mercury speciation by reversed-phase column high-performance liquid chromatography with UV-visible detection after solid-phase extraction using 6-mercaptopurine and dithizone. | Journal of AOAC International 20080101 |
New and emerging trends in the treatment of atopic dermatitis. | Patient preference and adherence 20080101 |
Hand-foot syndrome due to capecitabine. | Indian journal of dermatology 20080101 |
Adverse Drug Reactions (ADR) in the inPatients of Medicine Department of a Rural Tertiary Care Teaching Hospital and Influence of Pharmacovigilance in Reporting ADR. | Indian journal of pharmacology 20080101 |
Outcome after relapse among children with standard-risk acute lymphoblastic leukemia: Children's Oncology Group study CCG-1952. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071220 |
Raman spectroscopy of natural accumulated paraffins from rocks: evenkite, ozokerite and hatchetine. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20071215 |
[Azathioprine and 6-mercaptopurine for maintenance treatment in ulcerative colitis. A survey of a Cochrane review]. | Ugeskrift for laeger 20071210 |
The importance of disease associations and concomitant therapy for the long-term management of psoriasis patients. | Archives of dermatological research 20071201 |
Two cases of isolated symptomatic myocarditis induced by all-trans retinoic acid (ATRA). | Annals of hematology 20071201 |
A simple method for the preparation of PEG-6-mercaptopurine for oral administration. | Bioorganic & medicinal chemistry letters 20071201 |
Effect of chronic azathioprine treatment on germ-line transmission of Hprt mutation in mice. | Environmental and molecular mutagenesis 20071201 |
Should TPMT genotype and activity be used to monitor 6-mercaptopurine treatment in children with acute lymphoblastic leukaemia? | Journal of clinical pharmacy and therapeutics 20071201 |
Methotrexate following unsuccessful thiopurine therapy in pediatric Crohn's disease. | The American journal of gastroenterology 20071201 |
The role of xanthine oxidase in thiopurine metabolism: a case report. | Therapeutic drug monitoring 20071201 |
Drug Insight: pharmacology and toxicity of thiopurine therapy in patients with IBD. | Nature clinical practice. Gastroenterology & hepatology 20071201 |
Interaction between mercaptopurine and milk. | Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20071201 |
Successful treatment of steroid refractory active ulcerative colitis with natural interferon-beta--an open long-term trial. | Zeitschrift fur Gastroenterologie 20071201 |
Optimizing drug therapy in inflammatory bowel disease. | Current gastroenterology reports 20071201 |
Dexamethasone in the maintenance phase of acute lymphoblastic leukaemia treatment: is the risk of lethal infections too high? | European journal of cancer (Oxford, England : 1990) 20071101 |
Hepatotoxicity of 6-mercaptopurine (6-MP) and Azathioprine (AZA) in adult IBD patients. | The American journal of gastroenterology 20071101 |
[Optimization of immunomodulatory treatment with azathioprine or 6-mercaptopurine in inflammatory bowel disease]. | Gastroenterologia y hepatologia 20071101 |
Ulcerative colitis: diagnosis and treatment. | American family physician 20071101 |
[Current status of treatment of inflammatory bowel disease]. | Cirugia espanola 20071101 |
[Pharmacogenomics of acute lymphoblastic leukemia]. | Medecine sciences : M/S 20071101 |
[A short duration treatment with intensive consolidation therapy for patients with acute myelogenous leukemia--13 year experience in a single institute]. | Gan to kagaku ryoho. Cancer & chemotherapy 20071101 |
[Prediction of adverse drug reactions based on genomic information]. | Nihon rinsho. Japanese journal of clinical medicine 20071028 |
[Ulcerative colitis]. | Nihon rinsho. Japanese journal of clinical medicine 20071028 |
Influence of the solution pH in the 6-mercaptopurine self-assembled monolayer (6MP-SAM) on a Au(111) single-crystal electrode. | Langmuir : the ACS journal of surfaces and colloids 20071023 |
Chemoprophylaxis of colorectal cancer in inflammatory bowel disease: current concepts. | Inflammatory bowel diseases 20071001 |
The low frequency of defective TPMT alleles in Turkish population: a study on pediatric patients with acute lymphoblastic leukemia. | American journal of hematology 20071001 |
Corticosteroid-dependent eosinophilic oesophagitis: azathioprine and 6-mercaptopurine can induce and maintain long-term remission. | European journal of gastroenterology & hepatology 20071001 |
Medical management of mild to moderate Crohn's disease: evidence-based treatment algorithms for induction and maintenance of remission. | Alimentary pharmacology & therapeutics 20071001 |
[Common errors in the management of outpatients with inflammatory bowel disease]. | Gastroenterologia y hepatologia 20071001 |
A critical analysis of barriers to the clinical implementation of pharmacogenomics. | Therapeutics and clinical risk management 20071001 |
Substitution of oral and intravenous thioguanine for mercaptopurine in a treatment regimen for children with standard risk acute lymphoblastic leukemia: a collaborative Children's Oncology Group/National Cancer Institute pilot trial (CCG-1942). | Pediatric blood & cancer 20070901 |
Mucormycosis presenting as recurrent gastric perforation in a patient with Crohn's disease on glucocorticoid, 6-mercaptopurine, and infliximab therapy. | Digestive diseases and sciences 20070901 |
Liver injury in inflammatory bowel disease: long-term follow-up study of 786 patients. | Inflammatory bowel diseases 20070901 |
Induction of acute lymphocytic leukemia differentiation by maintenance therapy. | Leukemia 20070901 |
Adverse reaction caused by excipients in mercaptopurine tablets. | The Annals of pharmacotherapy 20070901 |
Phase II study of chemotherapy and stem cell transplantation for adult acute lymphoblastic leukemia or lymphoblastic lymphoma: Japan Clinical Oncology Group Study 9004. | Cancer science 20070901 |
Sequential evaluation of thiopurine methyltransferase, inosine triphosphate pyrophosphatase, and HPRT1 genes polymorphisms to explain thiopurines' toxicity and efficacy. | Alimentary pharmacology & therapeutics 20070901 |
Oral tacrolimus for steroid-dependent and steroid-resistant ulcerative colitis in children. | Journal of pediatric gastroenterology and nutrition 20070901 |
Effect of long-term low-dose prednisone on height velocity and disease activity in pediatric and adolescent patients with Crohn disease. | Journal of pediatric gastroenterology and nutrition 20070901 |
Pharmacogenetic significance of inosine triphosphatase. | Pharmacogenomics 20070901 |
Relevance of pharmacogenetic aspects of mercaptopurine metabolism in the treatment of interstitial lung disease. | Current opinion in pulmonary medicine 20070901 |
Translation of pharmacogenetic knowledge into cancer therapeutics. | Clinical advances in hematology & oncology : H&O 20070901 |
The management of hemophilia in elderly patients. | Clinical interventions in aging 20070901 |
Antimetabolite therapy for lesser-risk B-lineage acute lymphoblastic leukemia of childhood: a report from Children's Oncology Group Study P9201. | Blood 20070815 |
Importance of a hypervariable active-site residue in human Mu class glutathione transferases catalyzing the bioactivation of chemotherapeutic thiopurine prodrugs. | Biochimica et biophysica acta 20070801 |
The efficiency of a PAMAM dendrimer toward the encapsulation of the antileukemic drug 6-mercaptopurine. | Anti-cancer drugs 20070801 |
Should we test TPMT enzyme levels before starting azathioprine? | Hematology (Amsterdam, Netherlands) 20070801 |
A triangulation study of the clinician and patient experiences of the use of the immunosuppressant drugs azathioprine and 6-mercaptopurine for the management of inflammatory bowel disease. | Journal of clinical nursing 20070801 |
Severe pulmonary toxicity after azathioprine/6-mercaptopurine initiation for the treatment of inflammatory bowel disease. | Journal of clinical gastroenterology 20070801 |
Pharmacogenomics in drug-metabolizing enzymes catalyzing anticancer drugs for personalized cancer chemotherapy. | Current drug metabolism 20070801 |
Translating pharmacogenomics: challenges on the road to the clinic. | PLoS medicine 20070801 |
In vitro study of 6-mercaptopurine oxidation catalysed by aldehyde oxidase and xanthine oxidase. | Drug metabolism and pharmacokinetics 20070801 |
The nucleoside and nucleotide mixture (OG-VI) rescues intestinal-like epithelial cells from the cytotoxicity of chemotherapeutic agents. | The journal of medical investigation : JMI 20070801 |
Solid-phase extraction and spectrophotometric determination of mercury with 6-mercaptopurine in environmental samples. | Annali di chimica 20070801 |
Adherence to thiopurine treatment in out-patients with Crohn's disease. | Alimentary pharmacology & therapeutics 20070715 |
Development of ulcerative colitis in a patient with multiple sclerosis following treatment with interferon beta 1a. | World journal of gastroenterology 20070714 |
Thiopurine-induced liver injury in patients with inflammatory bowel disease: a systematic review. | The American journal of gastroenterology 20070701 |
Therapeutic drug use in women with Crohn's disease and birth outcomes: a Danish nationwide cohort study. | The American journal of gastroenterology 20070701 |
6-thioguanine nucleotide-adapted azathioprine therapy does not lead to higher remission rates than standard therapy in chronic active crohn disease: results from a randomized, controlled, open trial. | Clinical chemistry 20070701 |
The rate of hepatitis B and C virus infections and the importance of HBV vaccination in children with acute lymphoblastic leukemia. | Hepatology research : the official journal of the Japan Society of Hepatology 20070701 |
Immune response to influenza vaccine in pediatric patients with inflammatory bowel disease. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20070701 |
Medical therapy and birth outcomes in women with Crohn's disease: what should we tell our patients? | The American journal of gastroenterology 20070701 |
Disseminated intravascular coagulation in acute leukemia at presentation and during induction therapy. | Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20070701 |
Leupeptin inhibits ventilator-induced diaphragm dysfunction in rats. | American journal of respiratory and critical care medicine 20070601 |
Pneumocystis jiroveci (carinii) pneumonia after infliximab therapy: a review of 84 cases. | Digestive diseases and sciences 20070601 |
Human glutathione transferases catalyzing the bioactivation of anticancer thiopurine prodrugs. | Biochemical pharmacology 20070601 |
Management of steroid-dependent ulcerative colitis: immunomodulatory agents, biologics, or surgery? | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20070601 |
Microscopic colitis. | Current treatment options in gastroenterology 20070601 |
[Current status of inflammatory bowel disease treatment]. | Revista clinica espanola 20070601 |
Erythema nodosum-like eruption as a manifestation of azathioprine hypersensitivity in patients with inflammatory bowel disease. | Archives of dermatology 20070601 |
Evaluation of renal function in Turkish children receiving BFM-95 therapy for acute lymphoblastic leukemia. | Pediatric hematology and oncology 20070601 |
Hand-foot syndrome with scleroderma-like change induced by the oral capecitabine: a case report. | The Korean journal of internal medicine 20070601 |
[Treatment of chronic inflammatory bowel diseases]. | Bulletin de l'Academie nationale de medecine 20070601 |
6-Mercaptopurine, an activator of Nur77, enhances transcriptional activity of HIF-1alpha resulting in new vessel formation. | Oncogene 20070531 |
What can we learn from geographical comparisons of childhood cancer survival? | British journal of cancer 20070521 |
Differential effects of targeted disruption of thiopurine methyltransferase on mercaptopurine and thioguanine pharmacodynamics. | Cancer research 20070515 |
Reinduction of relapsed acute promyelocytic leukemia with ATRA and low dose antimetabolite-based chemotherapy. | Pediatric blood & cancer 20070501 |
Studies of interactions among cobalt(III) polypyridyl complexes, 6-mercaptopurine and DNA. | Bioelectrochemistry (Amsterdam, Netherlands) 20070501 |
Application of HPLC to study the kinetics of a branched bi-enzyme system consisting of hypoxanthine-guanine phosphoribosyltransferase and xanthine oxidase--an important biochemical system to evaluate the efficiency of the anticancer drug 6-mercaptopurine in ALL cell line. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070501 |
Thiopurine methyltransferase activity in Spain: a study of 14,545 patients. | Digestive diseases and sciences 20070501 |
Assessment of thiopurine methyltransferase enzyme activity is superior to genotype in predicting myelosuppression following azathioprine therapy in patients with inflammatory bowel disease. | Alimentary pharmacology & therapeutics 20070501 |
Management of inflammatory bowel disease in adults. | Journal of digestive diseases 20070501 |
Thiopurine metabolite monitoring in paediatric inflammatory bowel disease. | Alimentary pharmacology & therapeutics 20070415 |
Synthesis and biological evaluation of some 6-substituted purines. | European journal of medicinal chemistry 20070401 |
Relationship between 6-mercaptopurine dose and 6-thioguanine nucleotide levels in patients with inflammatory bowel disease. | Inflammatory bowel diseases 20070401 |
Azathioprine and breastfeeding: is it safe? | BJOG : an international journal of obstetrics and gynaecology 20070401 |
Comment: Breast-feeding during maternal use of azathioprine. | The Annals of pharmacotherapy 20070401 |
Risk of fecal diversion in complicated perianal Crohn's disease. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20070401 |
Impact of FLT3 internal tandem duplications on Indian acute promyelocytic leukemia patients: prognostic implications. | Hematology (Amsterdam, Netherlands) 20070401 |
Anticancer nucleobase analogues 6-mercaptopurine and 6-thioguanine are novel substrates for equilibrative nucleoside transporter 2. | International journal of pharmaceutics 20070321 |
T-cell acute lymphoblastic leukemia relapsing as acute myelogenous leukemia. | Pediatric blood & cancer 20070301 |
Autologous transplantation of CD133 selected hematopoietic progenitor cells for treatment of relapsed acute lymphoblastic leukemia. | Pediatric blood & cancer 20070301 |
Adolescents with acute lymphoblastic leukaemia: outcome on UK national paediatric (ALL97) and adult (UKALLXII/E2993) trials. | Pediatric blood & cancer 20070301 |
Improved outcome in childhood acute myeloid leukemia in Singapore with the MRC AML 10 protocol. | Pediatric blood & cancer 20070301 |
Should ileoanal pouch surgery be staged for patients with mucosal ulcerative colitis on immunosuppressives? | International journal of colorectal disease 20070301 |
Novel DNA lesions generated by the interaction between therapeutic thiopurines and UVA light. | DNA repair 20070301 |
Synthesis and antiproliferative properties of N3/8-disubstituted 3,8-diazabicyclo[3.2.1]octane analogues of 3,8-bis[2-(3,4,5-trimethoxyphenyl)pyridin-4-yl]methyl-piperazine. | European journal of medicinal chemistry 20070301 |
[Combination therapy with low-dose cyclosporin A, azathiopurine, and prednisolone for a child with refractory chronic idiopathic thrombocytopenic purpura]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20070301 |
6-mercaptopurine (6-MP) entrapped stealth liposomes for improvement of leukemic treatment without hepatotoxicity and nephrotoxicity. | Cancer investigation 20070301 |
Almost normal cognitive function in patients during therapy for childhood acute lymphoblastic leukemia without cranial irradiation according to ALL-BFM 95 and COALL 06-97 protocols: results of an Austrian-German multicenter longitudinal study and implications for follow-up. | Pediatric hematology and oncology 20070301 |
Targeting nanomedicines in the treatment of Crohn's disease: focus on certolizumab pegol (CDP870). | International journal of nanomedicine 20070301 |
Isolated pulmonary Langerhans cell histiocytosis presenting with recurrent pneumothorax. | Pediatric blood & cancer 20070201 |
Cytotoxic effects of histone deacetylase inhibitor FK228 (depsipeptide, formally named FR901228) in combination with conventional anti-leukemia/lymphoma agents against human leukemia/lymphoma cell lines. | Investigational new drugs 20070201 |
Pancytopenia due to high 6-methylmercaptopurine levels in a 6-mercaptopurine treated patient with Crohn's disease. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20070201 |
Efficient screening method of the thiopurine methyltransferase polymorphisms for patients considering taking thiopurine drugs in a Chinese Han population in Henan Province (central China). | Clinica chimica acta; international journal of clinical chemistry 20070201 |
Results of the PETHEMA ALL-96 trial in elderly patients with Philadelphia chromosome-negative acute lymphoblastic leukemia. | European journal of haematology 20070201 |
Medium-term results of oral tacrolimus treatment in refractory inflammatory bowel disease. | Inflammatory bowel diseases 20070201 |
Pharmacogenomics in cancer treatment defining genetic bases for inter-individual differences in responses to chemotherapy. | Current opinion in pediatrics 20070201 |
Nonadherence with thiopurine immunomodulator and mesalamine medications in children with Crohn disease. | Journal of pediatric gastroenterology and nutrition 20070201 |
A nudge in the right direction: shaping the metabolic fate of thiopurines for therapeutic gain. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20070201 |
Effect of allopurinol on clinical outcomes in inflammatory bowel disease nonresponders to azathioprine or 6-mercaptopurine. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20070201 |
Crohn's disease of the esophagus. | Current treatment options in gastroenterology 20070201 |
Monitoring of thiopurine methyltransferase activity in postsurgical patients with Crohn's disease during 1 year of treatment with azathioprine or mesalazine. | Therapeutic drug monitoring 20070201 |
Analysis of ITPA phenotype-genotype correlation in the Bulgarian population revealed a novel gene variant in exon 6. | Therapeutic drug monitoring 20070201 |
Nature and position of functional group on thiopurine substrates influence activity of xanthine oxidase--enzymatic reaction pathways of 6-mercaptopurine and 2-mercaptopurine are different. | Biochemistry. Biokhimiia 20070201 |
Activation of nuclear receptor Nur77 by 6-mercaptopurine protects against neointima formation. | Circulation 20070130 |
Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis. | The Cochrane database of systematic reviews 20070124 |
Prognostic role of the reduced folate carrier, the major membrane transporter for methotrexate, in childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070115 |
Pulses of vincristine and dexamethasone in addition to intensive chemotherapy for children with intermediate-risk acute lymphoblastic leukaemia: a multicentre randomised trial. | Lancet (London, England) 20070113 |
Targeting the cerebrovascular large neutral amino acid transporter (LAT1) isoform using a novel disulfide-based brain drug delivery system. | Drug delivery 20070101 |
Radiation-induced meningioma following prophylactic radiotherapy for acute lymphoblastic leukemia in childhood. | Pediatric neurosurgery 20070101 |
Meta-analysis of risk of malignancy with immunosuppressive drugs in inflammatory bowel disease. | The Annals of pharmacotherapy 20070101 |
Glutathione-S-transferase genotypes and the adverse effects of azathioprine in young patients with inflammatory bowel disease. | Inflammatory bowel diseases 20070101 |
Pouch outcomes among children with ulcerative colitis treated with calcineurin inhibitors before ileal pouch anal anastomosis surgery. | Journal of pediatric surgery 20070101 |
Birth outcome in women treated with azathioprine or mercaptopurine during pregnancy: A Danish nationwide cohort study. | Alimentary pharmacology & therapeutics 20070101 |
[Case of severe ulcerative colitis successfully treated with intravenous cyclosporine without high dose corticosteroid]. | Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20070101 |
Steroid treatment for severe acute cryptogenic hepatitis. | Zeitschrift fur Gastroenterologie 20070101 |
On the action of methotrexate and 6-mercaptopurine on M. avium subspecies paratuberculosis. | PloS one 20070101 |
Individualized drug therapy. | Current opinion in drug discovery & development 20070101 |
Inflammatory bowel disease: past, present, and future. | Journal of gastroenterology 20070101 |
Thiopurine treatment in inflammatory bowel disease: clinical pharmacology and implication of pharmacogenetically guided dosing. | Clinical pharmacokinetics 20070101 |
Gastroparesis in patients with inactive Crohn's disease: a case series. | BMC gastroenterology 20070101 |
Rasburicase represents a new tool for hyperuricemia in tumor lysis syndrome and in gout. | International journal of medical sciences 20070101 |
Impact of pharmacogenomics on clinical practice in oncology. | Molecular diagnosis & therapy 20070101 |
Genetic tests for predicting the toxicity and efficacy of anticancer chemotherapy. | Neoplasma 20070101 |
Eruptive post-chemotherapy in situ melanomas and dysplastic nevi. | Pediatric dermatology 20070101 |
Adolescent adherence to oral therapy for leukemia: a focus group study. | Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses 20070101 |
[Influence of antitumor preparations on the concentration of free radicals in cells of Fusarium bulbigenum var. blasticola fungus during primary and tumour-like secondary growth]. | Biofizika 20070101 |
Resolution of disseminated fusariosis in a child with acute leukemia treated with combined antifungal therapy: a case report. | BMC infectious diseases 20070101 |
Preferential inhibition of xanthine oxidase by 2-amino-6-hydroxy-8-mercaptopurine and 2-amino-6-purine thiol. | BMC biochemistry 20070101 |
Daunorubicin-induced cell kill with 1-hour versus 24-hour infusions: a randomized comparison in children with newly diagnosed acute lymphoblastic leukemia. | Klinische Padiatrie 20070101 |
The patient with persistent perianal fistulae. | Best practice & research. Clinical gastroenterology 20070101 |
On the action of 5-amino-salicylic acid and sulfapyridine on M. avium including subspecies paratuberculosis. | PloS one 20070101 |
[Modified BFM-90 regimen greatly improves treatment outcomes of chinese childhood and adolescent lymphoblastic lymphoma]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20070101 |
Fludarabine, treosulfan and etoposide sensitivity and the outcome of hematopoietic stem cell transplantation in childhood acute myeloid leukemia. | Anticancer research 20070101 |
[Comparison of the present and previously used protocol of risk stratification in children with acute lymphoblastic leukemia]. | Medycyna wieku rozwojowego 20070101 |
Long-term graft function after allogeneic islet transplantation. | Cell transplantation 20070101 |
Infliximab therapy in children and adolescents with inflammatory bowel disease. | Drugs 20070101 |
Thiopurine treatment in inflammatory bowel disease. | Clinical pharmacokinetics 20070101 |
[The results of a multicenter trial of acute lymphoblastic leukemia treatment on ALL-MB 91/ALL-BFM 90m in children: analysis of efficacy and toxicity]. | Terapevticheskii arkhiv 20070101 |
Crystal structure of Leishmania tarentolae hypoxanthine-guanine phosphoribosyltransferase. | BMC structural biology 20070101 |
[Combination of purine analogues and aminosalicylates in patients with inflammatory bowel disease: why and how?]. | Gastroenterologie clinique et biologique 20070101 |
[Clinical manifestation of hepatotoxic effect of cytostatic chemicals]. | Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20070101 |
Azathioprine: a guide for the management of dermatology patients. | Dermatologic therapy 20070101 |
Myasthenia gravis. | Orphanet journal of rare diseases 20070101 |
Morphine in children with cancer: impact of age, chemotherapy and other factors on protein binding. | Journal of pain & palliative care pharmacotherapy 20070101 |
Acute lymphoblastic leukemia in a patient with chronic cyanoacrylate exposure. | Acta haematologica 20070101 |
Azathioprine in dermatology. | Acta dermatovenerologica Croatica : ADC 20070101 |
Maintenance of medically induced remission of Crohn's disease. | Digestion 20070101 |
Maintenance of surgically induced remission of Crohn's disease. | Digestion 20070101 |
Extraintestinal manifestations of Crohn's disease. | Digestion 20070101 |
Pregnancy and breastfeeding in patients with Crohn's disease. | Digestion 20070101 |
Drug safety in Crohn's disease therapy. | Digestion 20070101 |
Survival analysis. | Methods in molecular biology (Clifton, N.J.) 20070101 |
Infliximab: the evidence for its place in therapy in ulcerative colitis. | Core evidence 20070101 |
Certolizumab pegol: an evidence-based review of its place in the treatment of Crohn's disease. | Core evidence 20070101 |
Refractory ulcerative colitis treatment. | Gastroenterology & hepatology 20070101 |
Body mass index does not influence pharmacokinetics or outcome of treatment in children with acute lymphoblastic leukemia. | Blood 20061215 |
Lead compounds for antimalarial chemotherapy: purine base analogs discriminate between human and P. falciparum 6-oxopurine phosphoribosyltransferases. | Journal of medicinal chemistry 20061214 |
Authenticity and drug resistance in a panel of acute lymphoblastic leukaemia cell lines. | British journal of cancer 20061204 |
In vivo comparison of various polymeric and low molecular mass inhibitors of intestinal P-glycoprotein. | Biomaterials 20061201 |
Avascular necrosis--an antineoplastic-treatment-related toxicity: the experiences of two institutions. | Pediatric hematology and oncology 20061201 |
Insights in immunomodulatory therapies for ulcerative colitis and Crohn's disease. | Current gastroenterology reports 20061201 |
Adding pharmacogenetics information to drug labels: lessons learned. | Pharmacogenetics and genomics 20061201 |
Infliximab in ulcerative colitis. | Gastroenterology clinics of North America 20061201 |
Breast-feeding during maternal use of azathioprine. | The Annals of pharmacotherapy 20061201 |
Analysis of thiopurine S-methyltransferase polymorphism in the population of Serbia and Montenegro and mercaptopurine therapy tolerance in childhood acute lymphoblastic leukemia. | Therapeutic drug monitoring 20061201 |
Childhood CD4+/CD56+ hematodermic neoplasm: case report and review of the literature. | Haematologica 20061201 |
Favourable outcome in an APL patient with PLZF/RARalpha fusion gene: quantitative real-time RT-PCR confirms molecular response. | Haematologica 20061201 |
Review article: Medical therapy for fistulizing Crohn's disease. | Alimentary pharmacology & therapeutics 20061101 |
[Monitoring of thiopurine methyltransferase and thiopurine metabolites to optimize azathioprine therapy in inflammatory bowel disease]. | Gastroenterologia y hepatologia 20061101 |
[Risk of postoperative infection in patients with inflammatory bowel disease]. | The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20061101 |
Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) treated with 2-chlorodeoxyadenosine. | Pediatric blood & cancer 20061015 |
Thioguanine versus mercaptopurine in childhood ALL. | Lancet (London, England) 20061014 |
Toxicity and efficacy of 6-thioguanine versus 6-mercaptopurine in childhood lymphoblastic leukaemia: a randomised trial. | Lancet (London, England) 20061014 |
Pharmacogenetics during standardised initiation of thiopurine treatment in inflammatory bowel disease. | Gut 20061001 |
Utility of thiopurine methyltransferase genotyping and phenotyping, and measurement of azathioprine metabolites in the management of patients with autoimmune hepatitis. | Journal of hepatology 20061001 |
Decreased activity of clotting factor V during ALL consolidation treatment with mercaptopurine in a child. | The Annals of pharmacotherapy 20061001 |
Review article: can post-operative recurrence in Crohn's disease be prevented? | Alimentary pharmacology & therapeutics 20061001 |
Review article: the effect of aminosalicylates and immunomodulation on cancer risk in inflammatory bowel disease. | Alimentary pharmacology & therapeutics 20061001 |
Azathioprine as a postoperative prophylaxis reduces symptoms in aggressive Crohn's disease. | Scandinavian journal of gastroenterology 20061001 |
Exposure to thiopurine drugs through breast milk is low based on metabolite concentrations in mother-infant pairs. | British journal of clinical pharmacology 20061001 |
Leukocytapheresis in patients with moderate-severe steroid-dependant ulcerative colitis: clinical response without endoscopic response. | Inflammatory bowel diseases 20061001 |
The thiopurine methyltransferase genetic polymorphism is associated with thioguanine-related veno-occlusive disease of the liver in children with acute lymphoblastic leukemia. | Clinical pharmacology and therapeutics 20061001 |
Treatment of acute myeloid leukemia patients aged more than 75 years: results of the E-AML-01 trial of the Japanese Elderly Leukemia and Lymphoma Study Group (JELLSG). | Leukemia & lymphoma 20061001 |
[Postoperative recurrence in Crohn's disease. Risk factors and methods of prevention]. | La Tunisie medicale 20061001 |
[The clinical features of B cell lymphoblastic lymphoma and outcomes after BFM-90 regimen therapy]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20061001 |
Molecular mechanisms underlying the enhanced sensitivity of thiopurine-resistant T-lymphoblastic cell lines to methyl mercaptopurineriboside. | Biochemical pharmacology 20060928 |
A synthetic route to 9-(polyhydroxyalkyl)purines. | Carbohydrate research 20060925 |
Assembling of dimeric entities of Cd(II) with 6-mercaptopurine to afford one-dimensional coordination polymers: synthesis and scanning probe microscopy characterization. | Inorganic chemistry 20060918 |
Oral outpatient chemotherapy medication errors in children with acute lymphoblastic leukemia. | Cancer 20060915 |
Stabilization of gold nanoparticles by 6-mercaptopurine monolayers. Effects of the solvent properties. | The journal of physical chemistry. B 20060914 |
Symptomatic hypoglycemia: an unusual side effect of oral purine analogues for treatment of ALL. | Pediatric blood & cancer 20060901 |
Reduction in bioavailability of 6-mercaptopurine on simultaneous administration with cow's milk. | Pediatric hematology and oncology 20060901 |
Azathioprine in dermatology: the past, the present, and the future. | Journal of the American Academy of Dermatology 20060901 |
Review article: thiopurines in inflammatory bowel disease. | Alimentary pharmacology & therapeutics 20060901 |
[A case report: Severe bone marrow suppression caused by 6-mercaptopurin in Crohn's disease patient]. | Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20060901 |
Next steps on the thiopurine methyltransferase 6-thioguanine nucleotide pathway. | Journal of pediatric gastroenterology and nutrition 20060901 |
Evolution of thiopurine use in pediatric inflammatory bowel disease in an academic center. | Journal of pediatric gastroenterology and nutrition 20060901 |
[Twenty years of treating childhood acute lymphoblastic leukemia]. | Anales de pediatria (Barcelona, Spain : 2003) 20060901 |
Lack of cross-reactivity between 5-aminosalicylic acid-based drugs: a case report and review of the literature. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060901 |
AIDS-associated Burkitt or Burkitt-like lymphoma: short intensive polychemotherapy is feasible and effective. | Leukemia & lymphoma 20060901 |
Treatment of recurrent Langerhans cell histiocytosis in children with 2-chlorodeoxyadenosine. | Leukemia & lymphoma 20060901 |
Asparaginase (native ASNase or pegylated ASNase) in the treatment of acute lymphoblastic leukemia. | International journal of nanomedicine 20060901 |
Cancer treatment-induced mucositis pain: strategies for assessment and management. | Therapeutics and clinical risk management 20060901 |
Nine-year survival of lymphoblastic lymphoma patients. | Yonsei medical journal 20060831 |
Divergent activities of human glutathione transferases in the bioactivation of azathioprine. | Molecular pharmacology 20060801 |
Incidence of neoplasms in patients who develop sustained leukopenia during or after treatment with 6-mercaptopurine for inflammatory bowel disease. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20060801 |
TPMT, UGT1A1 and DPYD: genotyping to ensure safer cancer therapy? | Trends in pharmacological sciences 20060801 |
Case report: lymphoma arising in an ileal pouch anal anastomosis after immunomodulatory therapy for inflammatory bowel disease. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20060801 |
Genetic variants and the risk of Crohn's disease: what does it mean for future disease management? | Expert opinion on pharmacotherapy 20060801 |
Physical activity during treatment in children with leukemia: a pilot study. | Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 20060801 |
Remission on thiopurinic immunomodulators normalizes quality of life and psychological status in patients with Crohn's disease. | Inflammatory bowel diseases 20060801 |
Severe muscular weakness: an unusual adverse effect of azathioprine therapy. | Journal of clinical gastroenterology 20060801 |
Adverse events leading to modification of therapy in a large cohort of patients with inflammatory bowel disease. | Alimentary pharmacology & therapeutics 20060715 |
Synthesis, hydrolyses and dermal delivery of N-alkyl-N-alkyloxycarbonylaminomethyl (NANAOCAM) derivatives of phenol, imide and thiol containing drugs. | Bioorganic & medicinal chemistry letters 20060701 |
Systematic review of postoperative complications in patients with inflammatory bowel disease treated with immunomodulators. | The British journal of surgery 20060701 |
Postoperative maintenance therapy for inflammatory bowel disease. | Current opinion in gastroenterology 20060701 |
Bis(6-thioxo-1,6-dihydropurinium) tetrachlorozincate(II). | Acta crystallographica. Section C, Crystal structure communications 20060701 |
Pharmacogenetics in inflammatory bowel disease. | World journal of gastroenterology 20060621 |
Inhibition of inducible nitric oxide synthesis by azathioprine in a macrophage cell line. | Life sciences 20060620 |
Erythrocyte concentrations of metabolites or cumulative doses of 6-mercaptopurine and methotrexate do not predict liver changes in children treated for acute lymphoblastic leukemia. | Pediatric blood & cancer 20060601 |
Outcome of treatment in adults with Philadelphia chromosome-positive and/or BCR-ABL--positive acute lymphoblastic leukemia-retrospective analysis of Polish Adult Leukemia Group (PALG). | Annals of hematology 20060601 |
TR3 nuclear orphan receptor prevents cyclic stretch-induced proliferation of venous smooth muscle cells. | The American journal of pathology 20060601 |
Management of refractory ulcerative colitis. | Current treatment options in gastroenterology 20060601 |
Primary endobronchial anaplastic large cell lymphoma in a pediatric patient. | Puerto Rico health sciences journal 20060601 |
Does intravenous 6-mercaptopurine decrease salvage after relapse in childhood acute lymphoblastic leukemia? | Pediatric blood & cancer 20060501 |
Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
The significance of minimal residual disease kinetics in adults with newly diagnosed PML-RARalpha-positive acute promyelocytic leukemia: results of a prospective trial. | Haematologica 20060501 |
[HPLC determination and diversity analysis of thiopurine methyltransferase activity in human and pig]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20060501 |
Involvement of the concentrative nucleoside transporter 3 and equilibrative nucleoside transporter 2 in the resistance of T-lymphoblastic cell lines to thiopurines. | Biochemical and biophysical research communications 20060428 |
Determination of 6-mercaptopurine based on the fluorescence enhancement of Au nanoparticles. | Talanta 20060415 |
Monitoring of inosine monophosphate dehydrogenase activity in mononuclear cells of children with acute lymphoblastic leukemia: enzymological and clinical aspects. | Pediatric blood & cancer 20060401 |
Del(5q) and MLL amplification in homogeneously staining region in acute myeloblastic leukemia: a recurrent cytogenetic association. | Annals of hematology 20060401 |
6-Thioguanine-related hepatotoxicity in patients with inflammatory bowel disease: dose or level dependent? | Journal of hepatology 20060401 |
Risk of lymphoma: inflammatory bowel disease and immunomodulators. | Gut 20060401 |
Role of treatment intensification in infants with acute lymphoblastic leukemia: results of two consecutive AIEOP studies. | Haematologica 20060401 |
Chemoprevention of colorectal neoplasia in ulcerative colitis: the effect of 6-mercaptopurine. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20060401 |
Association of 6-thioguanine nucleotide levels and inflammatory bowel disease activity: a meta-analysis. | Gastroenterology 20060401 |
Infliximab plus azathioprine for steroid-dependent Crohn's disease patients: a randomized placebo-controlled trial. | Gastroenterology 20060401 |
When is too much enough? | Gastroenterology 20060401 |
Infliximab and azathioprine: bridge or parachute? | Gastroenterology 20060401 |
5-aminosalicylate therapy is associated with higher 6-thioguanine levels in adults and children with inflammatory bowel disease in remission on 6-mercaptopurine or azathioprine. | Inflammatory bowel diseases 20060401 |
Pregnane glycosides from Leptadenia pyrotechnica. | Journal of natural products 20060401 |
Inflammatory bowel disease in children: a pediatrician's perspective. | Minerva pediatrica 20060401 |
[Experimental methods in the treatment of Leśniowski-Crohn disease]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20060401 |
Infliximab for ulcerative colitis. | The New England journal of medicine 20060330 |
Orientation of 6-mercaptopurine SAMs at the silver electrode as studied by Raman mapping and in situ SERS. | The journal of physical chemistry. B 20060323 |
Case records of the Massachusetts General Hospital. Case 8-2006. A 71-year-old woman with Crohn's disease and altered mental status. | The New England journal of medicine 20060316 |
Leflunomide prevents alveolar fluid clearance inhibition by respiratory syncytial virus. | American journal of respiratory and critical care medicine 20060315 |
Chromosomal change during 6-mercaptopurine (6-MP) therapy in juvenile myelomonocytic leukemia: the growth of a 6-MP-refractory clone that already exists at onset. | Leukemia 20060301 |
Roles of protein C, protein S, and antithrombin III in acute leukemia. | American journal of hematology 20060301 |
American Gastroenterological Association Institute medical position statement on corticosteroids, immunomodulators, and infliximab in inflammatory bowel disease. | Gastroenterology 20060301 |
American Gastroenterological Association Institute technical review on corticosteroids, immunomodulators, and infliximab in inflammatory bowel disease. | Gastroenterology 20060301 |
Prevalence of methylenetetrahydrofolate reductase polymorphisms in young patients with inflammatory bowel disease. | Digestive diseases and sciences 20060301 |
How low is too low? Use of cluster analysis to define low levels of mercaptopurine metabolites. | Pediatric blood & cancer 20060201 |
Treatment adherence and 6-mercaptopurine metabolites. | Pediatric blood & cancer 20060201 |
Chronic liver disease related to 6-thioguanine in children with acute lymphoblastic leukaemia. | Journal of hepatology 20060201 |
Growth hormone deficiency after chemotherapy for acute lymphoblastic leukemia in children who have not received cranial radiation. | Pediatric blood & cancer 20060201 |
Predictors of immunomodulator use as early therapy in pediatric Crohn's disease. | Journal of clinical gastroenterology 20060201 |
Treatment of severe disseminated juvenile systemic xanthogranuloma with multiple lesions in the central nervous system. | Journal of pediatric hematology/oncology 20060201 |
JPN Guidelines for the management of acute pancreatitis: epidemiology, etiology, natural history, and outcome predictors in acute pancreatitis. | Journal of hepato-biliary-pancreatic surgery 20060201 |
[Wegener's granulomatosis: Pathogenesis, pathophysiology, and therapy]. | Nihon rinsho. Japanese journal of clinical medicine 20060201 |
Mechanistic mathematical modelling of mercaptopurine effects on cell cycle of human acute lymphoblastic leukaemia cells. | British journal of cancer 20060116 |
Thiopurine methyltransferase in acute lymphoblastic leukemia. | Blood 20060115 |
Is thiopurine therapy in ulcerative colitis as effective as in Crohn's disease? | Gut 20060101 |
Cyclosporine for severe ulcerative colitis. | The Annals of pharmacotherapy 20060101 |
Toxicity of infliximab in the course of treatment of Crohn's disease. | Expert opinion on drug safety 20060101 |
Pharmacogenomics and individualized drug therapy. | Annual review of medicine 20060101 |
Pharmacogenomics in inflammatory bowel disease. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20060101 |
A rash imposition from a lifestyle omission: a case report of pellagra. | The Ulster medical journal 20060101 |
Pharmacogenetics, adverse drug reactions and public health. | Community genetics 20060101 |
6-Thioguanine treatment in inflammatory bowel disease: a critical appraisal by a European 6-TG working party. | Digestion 20060101 |
Inflammatory bowel disease: current therapeutic options. | Digestion 20060101 |
Genetic polymorphisms of drug-metabolising enzymes and drug transporters in the chemotherapeutic treatment of cancer. | Clinical pharmacokinetics 20060101 |
The NR4A subgroup: immediate early response genes with pleiotropic physiological roles. | Nuclear receptor signaling 20060101 |
Anti-inflammatory and immunosuppressive drugs and reproduction. | Arthritis research & therapy 20060101 |
Choice of azathioprine or 6-mercaptopurine dose based on thiopurine methyltransferase (TPMT) activity to avoid myelosuppression. A prospective study. | Hepato-gastroenterology 20060101 |
Efficacy and tolerability of gemtuzumab ozogamicin (anti-CD33 monoclonal antibody, CMA-676, Mylotarg) in children with relapsed/refractory myeloid leukemia. | BMC cancer 20060101 |
The early history of chemical immunosuppression: 1900-1965. | Journal of nephrology 20060101 |
Overcoming the force and power of immunity: a history of immunosuppression in kidney transplantation. | Journal of nephrology 20060101 |
[Pharmacogenetics and pharmacogenomics]. | Bulletin de l'Academie nationale de medecine 20060101 |
[Xenobiotic-metabolizing polymorphic enzymes. An opportunity for individualized drug treatment]. | Bulletin de l'Academie nationale de medecine 20060101 |
Successful management of cerebral and pulmonary mucormycosis with liposomal amphotericin B in a 28-year-old woman with acute lymphoblastic leukemia. | Acta bio-medica : Atenei Parmensis 20060101 |
Guidelines for treatment with infliximab for Crohn's disease. | The Netherlands journal of medicine 20060101 |
Antidepressants and inflammatory bowel disease: a systematic review. | Clinical practice and epidemiology in mental health : CP & EMH 20060101 |
[Otoacoustic emissions measurements in children during the chemotherapy because of the acute lymphoblastic leukemia]. | Otolaryngologia polska = The Polish otolaryngology 20060101 |
Langerhans cell histiocytosis on the penis: a case report. | BMC urology 20060101 |
Current therapy of inflammatory bowel disease in children. | Paediatric drugs 20060101 |
No induction of thiopurine methyltransferase during thiopurine treatment in inflammatory bowel disease. | Nucleosides, nucleotides & nucleic acids 20060101 |
Impaired transport as a mechanism of resistance to thiopurines in human T-lymphoblastic leukemia cells. | Nucleosides, nucleotides & nucleic acids 20060101 |
Determination of ITPase activity in erythrocyte lysates obtained for determination of TPMT activity. | Nucleosides, nucleotides & nucleic acids 20060101 |
Acute ascending motoric paraplegia following intrathecal chemotherapy for treatment of acute lymphoblastic leukemia in children: case reports and review of the literature. | Klinische Padiatrie 20060101 |
Cytotoxic drug sensitivity of Epstein-Barr virus transformed lymphoblastoid B-cells. | BMC cancer 20060101 |
Thiopurine S-methyltransferase phenotype-genotype correlation in hemodialyzed patients. | Pharmacological reports : PR 20060101 |
Thiopurines, DNA damage, DNA repair and therapy-related cancer. | British medical bulletin 20060101 |
[Reults of treatment with protocols BFM 90 and BFM 95]. | Medicinski arhiv 20060101 |
[Auditory evoked potentials in patients after acute children's lymphoblastic leukemia treatment]. | Przeglad lekarski 20060101 |
Clinical pharmacogenomics of thiopurine S-methyltransferase. | Current clinical pharmacology 20060101 |
Medical management of Crohn's disease: current therapy and recent advances. | Expert review of clinical immunology 20060101 |
A randomized, postremission comparison of four courses of standard-dose consolidation therapy without maintenance therapy versus three courses of standard-dose consolidation with maintenance therapy in adults with acute myeloid leukemia: the Japan Adult Leukemia Study Group AML 97 Study. | Cancer 20051215 |
TPMT genotype and the use of thiopurines in paediatric inflammatory bowel disease. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20051201 |
The thiopurines: an update. | Investigational new drugs 20051201 |
Observations on the use of allopurinol in combination with azathioprine or mercaptopurine. | Alimentary pharmacology & therapeutics 20051201 |
Managing complicated Crohn's disease in children and adolescents. | Nature clinical practice. Gastroenterology & hepatology 20051201 |
West Nile virus infection in a teenage boy with acute lymphocytic leukemia in remission. | Journal of pediatric hematology/oncology 20051201 |
Simultaneous control of third-degree graft-versus-host disease and prevention of recurrence of juvenile myelomonocytic leukemia (JMML) with 6-mercaptopurine following fulminant JMML relapse early after KIR-mismatched bone marrow transplantation. | Journal of pediatric hematology/oncology 20051201 |
p16 inactivation associated with aggressive clinical course and fatal outcome in TEL/AML1-positive acute lymphoblastic leukemia. | Journal of pediatric hematology/oncology 20051201 |
Role of 5'-nucleotidase in thiopurine metabolism: enzyme kinetic profile and association with thio-GMP levels in patients with acute lymphoblastic leukemia during 6-mercaptopurine treatment. | Clinica chimica acta; international journal of clinical chemistry 20051101 |
Toxicity due to 6-thioquanine. | Pediatric blood & cancer 20051101 |
Effects of azathioprine and its metabolites on repair mechanisms of the intestinal epithelium in vitro. | Regulatory peptides 20051101 |
Liquid chromatography-tandem mass spectrometry analysis of erythrocyte thiopurine nucleotides and effect of thiopurine methyltransferase gene variants on these metabolites in patients receiving azathioprine/6-mercaptopurine therapy. | Clinical chemistry 20051101 |
Thiopurine S-methyltransferase pharmacogenetics: variant allele functional and comparative genomics. | Pharmacogenetics and genomics 20051101 |
Incidence, risk factors and clinical course of thiopurine-induced liver injury in patients with inflammatory bowel disease. | Alimentary pharmacology & therapeutics 20051101 |
Lymphoma after Imuran and 6-MP: a new look. | Journal of pediatric gastroenterology and nutrition 20051101 |
Drug therapy for the treatment of Langerhans cell histiocytosis. | Expert opinion on pharmacotherapy 20051101 |
Membranous glomerulopathy in children given allogeneic hematopoietic stem cell transplantation. | Haematologica 20051101 |
Intracranial plasma cell granuloma: case report and treatment of recurrence with methotrexate and 6-mercaptopurine. | Journal of pediatric hematology/oncology 20051101 |
6-Thioguanine for Crohn's disease during pregnancy: thiopurine metabolite measurements in both mother and child. | Scandinavian journal of gastroenterology 20051101 |
Alert: 6-mercaptopurine may be erroneously dispensed instead of propylthiouracil. | Thyroid : official journal of the American Thyroid Association 20051101 |
Treatment with all-trans retinoic acid and anthracycline monochemotherapy for children with acute promyelocytic leukemia: a multicenter study by the PETHEMA Group. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20051020 |
[Crohn's disease--standards of treatment 2004]. | Praxis 20051012 |
The risk of lymphoma in the treatment of inflammatory bowel disease with immunosuppressive agents. | Critical reviews in oncology/hematology 20051001 |
Low-dose oral methotrexate for maintaining Crohn's disease remission: where we stand. | Journal of clinical gastroenterology 20051001 |
Genetic determinants of cancer drug efficacy and toxicity: practical considerations and perspectives. | Anti-cancer drugs 20051001 |
The impact of age and gender on biology, clinical features and treatment outcome of non-Hodgkin lymphoma in childhood and adolescence. | British journal of haematology 20051001 |
Thiopurine therapies: problems, complexities, and progress with monitoring thioguanine nucleotides. | Therapeutic drug monitoring 20051001 |
The pharmacokinetic effect of discontinuation of mesalazine on mercaptopurine metabolite levels in inflammatory bowel disease patients. | Alimentary pharmacology & therapeutics 20051001 |
A cost-effectiveness analysis of alternative disease management strategies in patients with Crohn's disease treated with azathioprine or 6-mercaptopurine. | The American journal of gastroenterology 20051001 |
Thiopurine methyltransferase and 6-thioguanine nucleotide measurement: early experience of use in clinical practice. | Internal medicine journal 20051001 |
Chemoprevention of colorectal neoplasia in ulcerative colitis: the effect of 6-mercaptopurine. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20051001 |
Excellent response of chemotherapy-resistant B-cell-type chronic lymphocytic leukemia with meningeal involvement to rituximab. | International journal of clinical oncology 20051001 |
A prospective, open-label trial of 6-thioguanine in patients with ulcerative or indeterminate colitis. | Scandinavian journal of gastroenterology 20051001 |
On tolerability and safety of a maintenance treatment with 6-thioguanine in azathioprine or 6-mercaptopurine intolerant IBD patients. | World journal of gastroenterology 20050921 |
[Thiopurine methyltransferase activity in inflammatory bowel disease. A study on 7046 Spanish patients]. | Medicina clinica 20050910 |
[Erythrocyte activity of thiopurine methyltransferase and treatment with thiopurines in inflammatory bowel disease]. | Medicina clinica 20050910 |
Gene expression and thioguanine nucleotide disposition in acute lymphoblastic leukemia after in vivo mercaptopurine treatment. | Blood 20050901 |
Fluorometric investigation of the interaction of bovine serum albumin with surfactants and 6-mercaptopurine. | Journal of photochemistry and photobiology. B, Biology 20050901 |
The yicM (nepI) gene of Escherichia coli encodes a major facilitator superfamily protein involved in efflux of purine ribonucleosides. | FEMS microbiology letters 20050901 |
Drug-induced pancreatitis: an update. | Journal of clinical gastroenterology 20050901 |
Azathioprine pancreatitis in inflammatory bowel disease and successful subsequent treatment with mercaptopurine. | Internal medicine journal 20050901 |
Allopurinol safely and effectively optimizes tioguanine metabolites in inflammatory bowel disease patients not responding to azathioprine and mercaptopurine. | Alimentary pharmacology & therapeutics 20050901 |
On the limitation of 6-tioguaninenucleotide monitoring during tioguanine treatment. | Alimentary pharmacology & therapeutics 20050901 |
Nuclear winter. | Transfusion 20050901 |
A survey of Canadian gastroenterologists about the use of methotrexate in patients with Crohn's disease. | Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20050901 |
Pharmacokinetics of azathioprine following single-dose intravenous and oral administration and effects of azathioprine following chronic oral administration in horses. | American journal of veterinary research 20050901 |
Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles. | British journal of cancer 20050822 |
Adsorption of 6-mercaptopurine and 6-mercaptopurine-ribosideon silver colloid: a pH-dependent surface-enhanced Raman spectroscopy and density functional theory study. II. 6-mercaptopurine-riboside. | Biopolymers 20050815 |
[Epstein-Barr virus-related lymphomas in patients with inflammatory bowel disease]. | Nederlands tijdschrift voor geneeskunde 20050813 |
Suboptimal physician adherence to quality indicators for the management of gout and asymptomatic hyperuricaemia: results from the UK General Practice Research Database (GPRD). | Rheumatology (Oxford, England) 20050801 |
Increased risk of lymphoma among inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurine. | Gut 20050801 |
Use of endoscopic ultrasound to guide combination medical and surgical therapy for patients with Crohn's perianal fistulas. | Inflammatory bowel diseases 20050801 |
The impact of thiopurine s-methyltransferase polymorphism on azathioprine-induced myelotoxicity in renal transplant recipients. | Therapeutic drug monitoring 20050801 |
Azathioprine and 6-mercaptopurine pharmacogenetics and metabolite monitoring in inflammatory bowel disease. | Journal of gastroenterology and hepatology 20050801 |
Successful bone marrow transplantation for life threatening xanthogranuloma disseminatum in neurofibromatosis type-1. | Pediatric transplantation 20050801 |
Liposomal formulations of inflammatory bowel disease drugs: local versus systemic drug delivery in a rat model. | Pharmaceutical research 20050801 |
Development of hepatocellular carcinoma following treatment with 6-mercaptopurine for ulcerative colitis: investigation of chromosomal aberration by comparative genomic hybridization. | International journal of clinical oncology 20050801 |
Interventions for growth failure in childhood Crohn's disease. | The Cochrane database of systematic reviews 20050720 |
Factors affecting recurrence after surgery for Crohn's disease. | World journal of gastroenterology 20050714 |
Interference free and simplyfied liquid chromatography-based determination of thiopurine S-methyltransferase activity in erythrocytes. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050705 |
Intravenous 6-mercaptopurine decreases salvage after relapse in childhood acute lymphoblastic leukemia: a report from the Children's Cancer Group study CCG 1922. | Pediatric blood & cancer 20050701 |
Do minor differences in primary therapy influence rescue-ability after relapse in childhood ALL? | Pediatric blood & cancer 20050701 |
In vitro activity of imatinib in cells from patients with adult acute lymphoblastic leukemia. | Anti-cancer drugs 20050701 |
Thiopurine S-methyltransferase as a target for drug interactions. | European journal of clinical pharmacology 20050701 |
Review article: practical management of inflammatory bowel disease patients taking immunomodulators. | Alimentary pharmacology & therapeutics 20050701 |
Rosai-Dorfman disease: successful long-term results by combination chemotherapy with prednisone, 6-mercaptopurine, methotrexate, and vinblastine: a case report. | International journal of surgical pathology 20050701 |
Modeling of purine derivatives transport across cell membranes based on their partition coefficient determination and quantum chemical calculations. | Journal of medicinal chemistry 20050630 |
Pharmacogenetics of outcome in children with acute lymphoblastic leukemia. | Blood 20050615 |
Immunophenotypic cell lineage and in vitro cellular drug resistance in childhood relapsed acute lymphoblastic leukaemia. | European journal of cancer (Oxford, England : 1990) 20050601 |
Predicting drug response and toxicity based on gene polymorphisms. | Critical reviews in oncology/hematology 20050601 |
Appropriateness of immunosuppressive drugs in inflammatory bowel diseases assessed by RAND method: Italian Group for IBD (IG-IBD) position statement. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20050601 |
Pediatric inflammatory bowel disease: what children can teach adults. | Inflammatory bowel diseases 20050601 |
Are patients with inflammatory bowel disease receiving optimal care? | The American journal of gastroenterology 20050601 |
Determination of mercaptopurine and its four metabolites by large-volume sample stacking with polarity switching in capillary electrophoresis. | Electrophoresis 20050601 |
Azathioprine, 6-mercaptopurine and thiopurine S-methyltransferase. | Journal of gastroenterology and hepatology 20050601 |
TRAP220 is modulated by the antineoplastic agent 6-Mercaptopurine, and mediates the activation of the NR4A subgroup of nuclear receptors. | Journal of molecular endocrinology 20050601 |
Screening of catalytically active microorganisms for the synthesis of 6-modified purine nucleosides. | Biotechnology letters 20050601 |
Pyoderma gangrenosum associated with osteomyelitis in a paediatric patient: a case report. | The West Indian medical journal 20050601 |
[Pharmacogenetics of inflammatory bowel disease]. | Orvosi hetilap 20050522 |
[Individual monitoring of thiopurine and methotrexate treatment]. | Ugeskrift for laeger 20050516 |
[Immunosuppressive agents: Imurel and Purinethol]. | La Revue du praticien 20050515 |
Value of intravenous 6-mercaptopurine during continuation treatment in childhood acute lymphoblastic leukemia and non-Hodgkin's lymphoma: final results of a randomized phase III trial (58881) of the EORTC CLG. | Leukemia 20050501 |
The effect of 6-mercaptopurine on early human placental explants. | Human reproduction (Oxford, England) 20050501 |
Immunosuppressive efficacy of mycophenolate mofetil when compared with azathioprine and mizoribine against peripheral lymphocytes from renal transplant recipients. | Transplant international : official journal of the European Society for Organ Transplantation 20050501 |
Effects of aminosalicylates on thiopurine S-methyltransferase activity: an ex vivo study in patients with inflammatory bowel disease. | Alimentary pharmacology & therapeutics 20050501 |
Preventing postoperative recurrence in Crohn's disease with 6-mercaptopurine and azathioprine: approaching the cutting edge. | Inflammatory bowel diseases 20050501 |
[Immunosuppressants for therapy of patients with ulcerative colitis]. | Nihon rinsho. Japanese journal of clinical medicine 20050501 |
[Guidelines for treatment of ulcerative colitis in children]. | Nihon rinsho. Japanese journal of clinical medicine 20050501 |
Amphotericin B-induced nephrogenic diabetes insipidus in a case of cryptococcemia. | Internal medicine (Tokyo, Japan) 20050501 |
[Azathioprine]. | Nihon rinsho. Japanese journal of clinical medicine 20050501 |
Azathioprine induced nodular regenerative hyperplasia in IBD patients. | Gastroenterologie clinique et biologique 20050501 |
ITPA genotyping test does not improve detection of Crohn's disease patients at risk of azathioprine/6-mercaptopurine induced myelosuppression. | Gut 20050401 |
Promising treatment of autoimmune hepatitis with 6-thioguanine after adverse events on azathioprine. | European journal of gastroenterology & hepatology 20050401 |
Thiopurines in inflammatory bowel disease: pharmacogenetics, therapeutic drug monitoring and clinical recommendations. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20050401 |
6-tioguanine monitoring in steroid-dependent patients with inflammatory bowel diseases receiving azathioprine. | Alimentary pharmacology & therapeutics 20050401 |
Genotyping of thiopurine methyltransferase using pyrosequencing. | Biological & pharmaceutical bulletin 20050401 |
Sudden onset of Multiple nevi after administration of 6-mercaptopurine in an adult with Crohn's disease: a case report. | International journal of dermatology 20050401 |
Identification of genes associated with chemotherapy crossresistance and treatment response in childhood acute lymphoblastic leukemia. | Cancer cell 20050401 |
Effects of 6-mercaptopurine treatment on sperm production and reproductive performance: a study in male mice. | Scandinavian journal of gastroenterology 20050401 |
A simple hybrid variance estimator for the Kaplan-Meier survival function. | Statistics in medicine 20050330 |
Thiopurine methyltransferase (TPMT) genotype and early treatment response to mercaptopurine in childhood acute lymphoblastic leukemia. | JAMA 20050323 |
Portal hypertension develops in a subset of children with standard risk acute lymphoblastic leukemia treated with oral 6-thioguanine during maintenance therapy. | Pediatric blood & cancer 20050301 |
Infliximab efficacy in pediatric ulcerative colitis. | Inflammatory bowel diseases 20050301 |
Can we alter the natural history of Crohn disease in children? | Journal of pediatric gastroenterology and nutrition 20050301 |
Thiopurine methyltransferase in acute lymphoblastic leukaemia: biochemical and molecular biological aspects. | European journal of cancer (Oxford, England : 1990) 20050301 |
Measurement of thiopurine methyl transferase activity guides dose-initiation and prevents toxicity from azathioprine. | The New Zealand medical journal 20050225 |
Raman mapping and in situ SERS spectroelectrochemical studies of 6-mercaptopurine SAMs on the gold electrode. | The journal of physical chemistry. B 20050224 |
[Adolescents with acute lymphatic leukaemia achieve significantly better results when treated following Dutch paediatric oncology protocols than with adult protocols]. | Nederlands tijdschrift voor geneeskunde 20050219 |
Explained randomness in proportional hazards models. | Statistics in medicine 20050215 |
Review article: monitoring of immunomodulators in inflammatory bowel disease. | Alimentary pharmacology & therapeutics 20050215 |
[Inflammatory bowel disease--diagnosis and therapy]. | Praxis 20050202 |
Selective inhibition of inflammatory gene expression in activated T lymphocytes: a mechanism of immune suppression by thiopurines. | The Journal of pharmacology and experimental therapeutics 20050201 |
Mesenteric pulsatility index analysis predicts response to azathioprine in patients with Crohn's disease. | Inflammatory bowel diseases 20050201 |
Use of 6-mercaptopurine/azathioprine as the immunomodulator of choice for moderately active Crohn's disease: pro. | Inflammatory bowel diseases 20050201 |
Use of 6-mercapturine/azathioprine as the immunomodulator of choice for moderately active Crohn's disease: con. | Inflammatory bowel diseases 20050201 |
Use of 6-mercaptopurine/azathioprine as the immunomodulator of choice for moderately active Crohn's disease: balance. | Inflammatory bowel diseases 20050201 |
Hepatosplenic T-cell lymphoma in an adolescent patient after immunomodulator and biologic therapy for Crohn disease. | Journal of pediatric gastroenterology and nutrition 20050201 |
Cognitive changes in children treated for acute lymphoblastic leukemia with chemotherapy only according to the Pediatric Oncology Group 9605 protocol. | Journal of child neurology 20050201 |
Advanced-stage large-cell lymphoma in children and adolescents: results of a randomized trial incorporating intermediate-dose methotrexate and high-dose cytarabine in the maintenance phase of the APO regimen: a Pediatric Oncology Group phase III trial. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050120 |
[Treatment results with ALL-BFM-95 protocol in children with acute lymphoblastic leukemia in Hungary]. | Orvosi hetilap 20050109 |
The ten-year single-center experience with 6-mercaptopurine in the treatment of inflammatory bowel disease. | Journal of clinical gastroenterology 20050101 |
Pharmacology of drugs for hyperuricemia. Mechanisms, kinetics and interactions. | Contributions to nephrology 20050101 |
Azathioprine and 6 Mercaptopurine in postoperative maintenance of Crohn's disease remission: is no evidence of effect an evidence of no effect? | Gastroenterology 20050101 |
6-Mercaptopurine and mesalamine for prevention of relapse after conservative surgery for Crohn's disease. | Gastroenterology 20050101 |
Pharmacokinetics following intraventricular administration of chemotherapy in patients with neoplastic meningitis. | Clinical pharmacokinetics 20050101 |
Long-term oral tacrolimus therapy in refractory to infliximab fistulizing Crohn's disease: a pilot study. | Inflammatory bowel diseases 20050101 |
Extraintestinal manifestations of Crohn's disease. | Digestion 20050101 |
Maintenance of remission in Crohn's disease. | Digestion 20050101 |
Pregnancy and Crohn's disease. | Digestion 20050101 |
Cellular export of drugs and signaling molecules by the ATP-binding cassette transporters MRP4 (ABCC4) and MRP5 (ABCC5). | Drug metabolism reviews 20050101 |
Treatment of acute lymphocytic leukemia using zinc adjuvant with chemotherapy and radiation--a case history and hypothesis. | Medical hypotheses 20050101 |
6-mercaptopurine in patients with inflammatory bowel disease and previous digestive intolerance of azathioprine. | Scandinavian journal of gastroenterology 20050101 |
Comprehensive screening of the thiopurine methyltransferase polymorphisms by denaturing high-performance liquid chromatography. | Genetic testing 20050101 |
[Evaluation of compliance through specific interviews: a prospective study of 73 children with acute lymphoblastic leukemia]. | Jornal de pediatria 20050101 |
ATP-binding cassette (ABC) transporters in normal and pathological lung. | Respiratory research 20050101 |
Long-term outcome of ph-negative acute lymphoblastic leukaemia in adults: a single centre experience. | Acta haematologica 20050101 |
Folate system correlations in DNA microarray data. | BMC cancer 20050101 |
[Treatment of adult Berkitt-like lymphoma]. | Terapevticheskii arkhiv 20050101 |
Effects of 6-mercaptopurine (6-MP) on histomorphometric parameters of the rat bones. | Pharmacological reports : PR 20050101 |
Economic implications of biological therapies for Crohn's disease: review of infliximab. | PharmacoEconomics 20050101 |
Treatment of acute promyelocytic leukemia: a single institution experience. | Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20050101 |
Digital drug discovery. | Genome biology 20050101 |
[Pellagra]. | Sante (Montrouge, France) 20050101 |
Designing drugs. | American heritage of invention & technology 20050101 |
Nitrogen fertilizer recommendations for corn grown on soils amended with oily food waste. | Journal of environmental quality 20050101 |
Prognostic impact of age in children and adolescents with acute lymphoblastic leukemia: data from the trials ALL-BFM 86, 90, and 95. | Klinische Padiatrie 20050101 |
Nurr1 dependent regulation of pro-inflammatory mediators in immortalised synovial fibroblasts. | Journal of inflammation (London, England) 20050101 |
[Treatment results of Langerhans cell histiocytosis with LSH II protocol]. | Casopis lekaru ceskych 20050101 |
Electrochemical determination of 6-mercaptopurine at silver microdisk electrodes. | Annali di chimica 20050101 |
Impact of efalizumab on patient-reported outcomes in high-need psoriasis patients: results of the international, randomized, placebo-controlled Phase III Clinical Experience Acquired with Raptiva (CLEAR) trial [NCT00256139]. | BMC dermatology 20050101 |
6-mercaptopurine and daunorubicin double drug liposomes-preparation, drug-drug interaction and characterization. | Journal of liposome research 20050101 |
Medical therapy for ulcerative colitis: the state of the art and beyond. | Current gastroenterology reports 20041201 |
Advances in medical therapy for Crohn's disease. | Current gastroenterology reports 20041201 |
Childhood leukaemia: a relationship between intracellular 6-mercaptopurine metabolites and neutropenia. 1983. | British journal of clinical pharmacology 20041201 |
[Efficacy of modified BFM-90 regimen on children and adolescents with T cell lymphoblastic lymphoma: a report of 20 cases]. | Ai zheng = Aizheng = Chinese journal of cancer 20041201 |
Azathioprine acts upon rat hepatocyte mitochondria and stress-activated protein kinases leading to necrosis: protective role of N-acetyl-L-cysteine. | The Journal of pharmacology and experimental therapeutics 20041101 |
Acute promyelocytic leukemia and HIV-1 infection: case report and review of the literature. | American journal of hematology 20041101 |
Reviewing the mechanism of action of thiopurine drugs: towards a new paradigm in clinical practice. | Medical science monitor : international medical journal of experimental and clinical research 20041101 |
Use of laboratory testing to guide 6-mercaptopurine/azathioprine therapy. | Gastroenterology 20041101 |
Monitoring of long-term thiopurine therapy among adults with inflammatory bowel disease. | Scandinavian journal of gastroenterology 20041101 |
[Primary study of relationship between serum level of VEGF and non-Hodgkin's lymphoma in children and adolescent patients]. | Ai zheng = Aizheng = Chinese journal of cancer 20041101 |
Efficacy of conventional immunosuppressive drugs in IBD. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20041101 |
Therapeutic drug monitoring of thiopurine drugs in patients with inflammatory bowel disease or autoimmune hepatitis. | European journal of gastroenterology & hepatology 20041101 |
[Chronic inflammatory bowel diseases]. | Deutsche medizinische Wochenschrift (1946) 20041015 |
Establishment and characterisation of a human carcinoma cell line with acquired resistance to Aplidin. | British journal of cancer 20041004 |
Ulcerative colitis: conservative management and long-term effects. | Langenbeck's archives of surgery 20041001 |
Common variable immunodeficiency and the gastrointestinal tract. | Current gastroenterology reports 20041001 |
Review article: the long-term management of ulcerative colitis. | Alimentary pharmacology & therapeutics 20041001 |
Review article: chronic active disease and maintaining remission in Crohn's disease. | Alimentary pharmacology & therapeutics 20041001 |
Review article: treatment of perianal fistulizing Crohn's disease. | Alimentary pharmacology & therapeutics 20041001 |
Sperm, sex, and 6-MP: the perception on conception. | Gastroenterology 20041001 |
[Methotrexate-induced interstitial pneumonitis in a child with acute lymphoblastic leukemia]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20041001 |
The clinical impact of thiopurine methyltransferase polymorphisms on thiopurine treatment. | Nucleosides, nucleotides & nucleic acids 20041001 |
Allele frequency of inosine triphosphate pyrophosphatase gene polymorphisms in a Japanese population. | Nucleosides, nucleotides & nucleic acids 20041001 |
Consequences of binding an S-adenosylmethionine analogue on the structure and dynamics of the thiopurine methyltransferase protein backbone. | Biochemistry 20040928 |
Azathioprine formulation optimizes metabolite profile in inflammatory bowel disease. | Alimentary pharmacology & therapeutics 20040915 |
Inflammatory bowel disease: management issues during pregnancy. | Archives of gynecology and obstetrics 20040901 |
Acute lymphoblastic leukemia with TEL-AML1 fusion has lower expression of genes involved in purine metabolism and lower de novo purine synthesis. | Blood 20040901 |
Diagnosis of 6 mercaptopurine hepatotoxicity post liver transplantation utilizing metabolite assays. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040901 |
Early hepatic nodular hyperplasia and submicroscopic fibrosis associated with 6-thioguanine therapy in inflammatory bowel disease. | The American journal of surgical pathology 20040901 |
Experience with the use of low-dose methotrexate for inflammatory bowel disease. | European journal of gastroenterology & hepatology 20040901 |
Improved HPLC methodology for monitoring thiopurine metabolites in patients on thiopurine therapy. | Clinical biochemistry 20040901 |
The utility of 6-thioguanine metabolite levels in managing patients with inflammatory bowel disease. | The American journal of gastroenterology 20040901 |
Azathioprine, 6-mercaptopurine in inflammatory bowel disease: pharmacology, efficacy, and safety. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20040901 |
Postoperative maintenance of Crohn's disease remission with 6-mercaptopurine, mesalamine, or placebo: a 2-year trial. | Gastroenterology 20040901 |
The efficacy of azathioprine and 6-mercaptopurine for the prevention of postoperative recurrence in patients with Crohn's disease remains uncertain. | Gastroenterology 20040901 |
[Ulcerative colitis. Chronic active course]. | Zeitschrift fur Gastroenterologie 20040901 |
[Ulcerative colitis. Maintenance therapy]. | Zeitschrift fur Gastroenterologie 20040901 |
[Immunosuppressive therapy for inflammatory bowel disease: consensus by the Austrian working group on IBD]. | Zeitschrift fur Gastroenterologie 20040901 |
Could immunosuppressive drugs reduce recurrence rate after second resection for Crohn disease? | Inflammatory bowel diseases 20040901 |
Acute sinusoidal obstruction syndrome after 6-thioguanine therapy for Crohn's disease. | Inflammatory bowel diseases 20040901 |
[Life-threatening adverse effects of pharmacologic antihyperuricemic therapy]. | Therapeutische Umschau. Revue therapeutique 20040901 |
In vitro drug sensitivity and apoptosis induction in newly diagnosed pediatric acute lymphoblastic leukemia: correlation with overall survival. | Pediatric hematology and oncology 20040901 |
Drug therapy for ulcerative colitis. | World journal of gastroenterology 20040815 |
The fidelity of replication of the three-base-pair set adenine/thymine, hypoxanthine/cytosine and 6-thiopurine/5-methyl-2-pyrimidinone with T7 DNA polymerase. | The Biochemical journal 20040801 |
A comparison of red blood cell thiopurine metabolites in children with acute lymphoblastic leukemia who received oral mercaptopurine twice daily or once daily: a Pediatric Oncology Group study (now The Children's Oncology Group). | Pediatric blood & cancer 20040801 |
Clinical significance of azathioprine active metabolite concentrations in inflammatory bowel disease. | Gut 20040801 |
Synthesis and antiproliferative activity of 3-aryl-2-[1H(2H)-benzotriazol-1(2)-yl]acrylonitriles variously substituted: Part 4. | Farmaco (Societa chimica italiana : 1989) 20040801 |
Clinical and laboratory evaluation of compliance in acute lymphoblastic leukaemia. | Archives of disease in childhood 20040801 |
Organic anion transporter 3 is involved in the brain-to-blood efflux transport of thiopurine nucleobase analogs. | Journal of neurochemistry 20040801 |
[A systematic review of the clinical effectiveness of azathioprine in patients with ulcerative colitis]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20040801 |
Thiopurine drug adverse effects in a population of New Zealand patients with inflammatory bowel disease. | Pharmacoepidemiology and drug safety 20040801 |
How effective are the usual treatments for Crohn's disease? | Alimentary pharmacology & therapeutics 20040715 |
Efficacy and safety of thiopurinic immunomodulators (azathioprine and mercaptopurine) in steroid-dependent ulcerative colitis. | Alimentary pharmacology & therapeutics 20040715 |
The benefit of induction chemotherapy in patients age > or = 75 years. | Cancer 20040715 |
Medical approaches and future options in chronic active ulcerative colitis. | International journal of colorectal disease 20040701 |
Some cases demonstrating the clinical usefulness of therapeutic drug monitoring in thiopurine-treated inflammatory bowel disease patients. | European journal of gastroenterology & hepatology 20040701 |
Thiopurine methyltransferase: should it be measured before commencing thiopurine drug therapy? | Annals of clinical biochemistry 20040701 |
Indicators of clinical response to treatment with six-mercaptopurine or azathioprine in patients with inflammatory bowel disease. | Inflammatory bowel diseases 20040701 |
Infliximab therapy in pediatric Crohn's pouchitis. | Inflammatory bowel diseases 20040701 |
[A study on inclusion complexes of cyclodextrin with three anticancer xanthines by fluorescence]. | Guang pu xue yu guang pu fen xi = Guang pu 20040701 |
Using pharmacogenetics to improve drug safety and efficacy. | JAMA 20040616 |
High-dose melphalan and autotransplantation followed by post transplant maintenance chemotherapy for acute lymphoblastic leukemia in first remission. | Bone marrow transplantation 20040601 |
Pharmacokinetics of 6-mercaptopurine in patients with inflammatory bowel disease: implications for therapy. | Therapeutic drug monitoring 20040601 |
Frequency distribution of thiopurine S-methyltransferase activity in red blood cells of a healthy Japanese population. | Therapeutic drug monitoring 20040601 |
General principles of medical therapy of inflammatory bowel disease. | Gastroenterology clinics of North America 20040601 |
Treatment of inflammatory bowel disease with azathioprine and 6-mercaptopurine. | Gastroenterology clinics of North America 20040601 |
Medical management of severe ulcerative colitis. | Gastroenterology clinics of North America 20040601 |
Medical management of postoperative recurrence in Crohn's disease. | Gastroenterology clinics of North America 20040601 |
Medical management of the pregnant patient with inflammatory bowel disease. | Gastroenterology clinics of North America 20040601 |
Discordant erythrocyte sedimentation rate and C-reactive protein in children with inflammatory bowel disease taking azathioprine or 6-mercaptopurine. | Journal of pediatric gastroenterology and nutrition 20040501 |
Renal transport of organic compounds mediated by mouse organic anion transporter 3 (mOat3): further substrate specificity of mOat3. | Drug metabolism and disposition: the biological fate of chemicals 20040501 |
An improved HPLC method for the quantitation of 6-mercaptopurine and its metabolites in red blood cells. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20040501 |
Review article: The medical treatment of Crohn's perianal fistulas. | Alimentary pharmacology & therapeutics 20040501 |
Thiopurine methyltransferase activity influences clinical response to azathioprine in inflammatory bowel disease. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20040501 |
In vivo kinetics of micronuclei induction by bifunctional alkylating antineoplastics. | Mutagenesis 20040501 |
Toxic ingestion of 6-mercaptopurine by young siblings of pediatric oncology patients. | The Journal of pediatrics 20040501 |
Early postoperative complications are not increased in patients with Crohn's disease treated perioperatively with infliximab or immunosuppressive therapy. | The American journal of gastroenterology 20040501 |
Additional discussion on the safety of 6-mercaptopurine for childbearing patients with inflammatory bowel disease: a retrospective cohort study. | Gastroenterology 20040501 |
Pharmacogenetic determinants of outcome in acute lymphoblastic leukaemia. | British journal of haematology 20040501 |
Mycophenolate mofetil for the treatment of autoimmune hepatitis in patients refractory to standard therapy. | Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20040501 |
Comprehensive analysis of risk factors associating with Hepatitis B virus (HBV) reactivation in cancer patients undergoing cytotoxic chemotherapy. | British journal of cancer 20040405 |
Methylated metabolites of 6-mercaptopurine are associated with hepatotoxicity. | Clinical pharmacology and therapeutics 20040401 |
Bone marrow necrosis in a patient with acute promyelocytic leukemia during re-induction therapy with arsenic trioxide. | European journal of haematology 20040401 |
The effect on the fetus of medications used to treat pregnant inflammatory bowel-disease patients. | The American journal of gastroenterology 20040401 |
Pharmacogenetics of thiopurine S-methyltransferase and thiopurine therapy. | Therapeutic drug monitoring 20040401 |
Analytic aspects of monitoring therapy with thiopurine medications. | Therapeutic drug monitoring 20040401 |
The analysis of correlations between drug resistance and clinical/laboratory measures found in a group of children with all treated by ALL-BFM 90 protocol. | Bulletin du cancer 20040401 |
The risk of congenital abnormalities in children fathered by men treated with azathioprine or mercaptopurine before conception. | Alimentary pharmacology & therapeutics 20040315 |
A multiplexed allele-specific polymerase chain reaction assay for the detection of common thiopurine S-methyltransferase (TPMT) mutations. | Clinica chimica acta; international journal of clinical chemistry 20040301 |
Cytotoxicity of the novel glutathione-activated thiopurine prodrugs cis-AVTP [cis-6-(2-acetylvinylthio)purine] and trans-AVTG [trans-6-(2-acetylvinylthio)guanine] results from the National Cancer Institute's anticancer drug screen. | Drug metabolism and disposition: the biological fate of chemicals 20040301 |
Thiopurine S-methyltransferase polymorphisms: efficient screening method for patients considering taking thiopurine drugs. | European journal of clinical pharmacology 20040301 |
Enzyme-catalyzed activation of anticancer prodrugs. | Pharmacological reviews 20040301 |
A search for the optimal duration of treatment with 6-mercaptopurine for ulcerative colitis. | The American journal of gastroenterology 20040301 |
Toxicity of low dose azathioprine and 6-mercaptopurine in rat hepatocytes. Roles of xanthine oxidase and mitochondrial injury. | Journal of hepatology 20040301 |
Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase). | Pharmacogenetics 20040301 |
6-Mercaptopurine is effective in Crohn's disease without concomitant steroids. | Inflammatory bowel diseases 20040301 |
Pulmonary involvement in Crohn's disease report of a case and review of the literature. | Inflammatory bowel diseases 20040301 |
Pharmacogenetics and inflammatory bowel disease: progress and prospects. | Inflammatory bowel diseases 20040301 |
Effect of antimetabolite immunosuppressants on Flaviviridae, including hepatitis C virus. | Transplantation 20040227 |
Antagonist: Early surgical intervention in ulcerative colitis. | Gut 20040201 |
Healthy offspring in parents both receiving thiopurines. | Gastroenterology 20040201 |
Antitumor activity of sugar-modified cytosine nucleosides. | Cancer science 20040201 |
[Observation on treatment of post-remission acute myeloid leukemia patients by lingxiong piaoling powder and longchan cigu decoction]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040201 |
Azathioprine transport through rat skin and its immunosuppressive effect. | Die Pharmazie 20040201 |
Prolonged remission of severe Crohn's disease after fever and leukopenia caused by 6-mercaptopurine. | Digestive diseases and sciences 20040201 |
Pharmacogenomics and IBD: TPMT and thiopurines. | Inflammatory bowel diseases 20040201 |
Ulcerative proctitis. | Clinics in colon and rectal surgery 20040201 |
Cancer pharmacogenetics. | British journal of cancer 20040112 |
Bone marrow stroma damage induced by chemotherapy for acute lymphoblastic leukemia in children. | Pediatric research 20040101 |
Relevance of thiopurine methyltransferase status in rheumatology patients receiving azathioprine. | Rheumatology (Oxford, England) 20040101 |
Thiopurine methyltransferase (TPMT) genotype distribution in azathioprine-tolerant and -intolerant patients with various disorders. The impact of TPMT genotyping in predicting toxicity. | European journal of clinical pharmacology 20040101 |
Current therapy of ulcerative colitis in children. | Expert opinion on pharmacotherapy 20040101 |
Oral treatment of acute myeloid leukaemia with etoposide, thioguanine, and idarubicin (ETI) in elderly patients: a prospective randomised comparison with intravenous cytarabine, idarubicin, and thioguanine in the second and third treatment cycle. | European journal of haematology 20040101 |
Clinical utility of thiopurine S-methyltransferase genotyping. | American journal of pharmacogenomics : genomics-related research in drug development and clinical practice 20040101 |
Two-day induction with thymoglobulin in kidney transplantation: risks and benefits. | Transplantation proceedings 20040101 |
Thiopurine methyltransferase activity in red blood cells of dogs. | Journal of veterinary internal medicine 20040101 |
Maintenance therapy in childhood acute myeloid leukemia. | Annals of hematology 20040101 |
Maintenance of remission in Crohn's disease: current and emerging therapeutic options. | Drugs 20040101 |
Unintentional intravenous infusion of Golytely in a 4-year-old girl. | The Annals of pharmacotherapy 20040101 |
[Genetic polymorphism and treatment of chronic bowel inflammatory diseases: the example of azathioprine]. | Therapie 20040101 |
Acute lymphoblastic leukemia in infants. | The Turkish journal of pediatrics 20040101 |
Human red blood cells: rheological aspects, uptake, and release of cytotoxic drugs. | Critical reviews in clinical laboratory sciences 20040101 |
Metals and metal compounds in cancer treatment. | Anticancer research 20040101 |
All-transretinoic acid and chemotherapy in the treatment of acute promyelocytic leukemia. | Indian journal of cancer 20040101 |
PEG prodrugs of 6-mercaptopurine for parenteral administration using benzyl elimination of thiols. | Oncology research 20040101 |
[Immunotherapy of inflammatory bowel diseases]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20040101 |
Management of ulcerative colitis and Crohn's disease. | Acta clinica Belgica 20040101 |
[Immunosupressants and MICI]. | Gastroenterologie clinique et biologique 20040101 |
[Treatment results in children with standard-risk acute lymphoblastic leukemia. Report of the Polish Pediatric Leukemia/Lymphoma Study Group]. | Przeglad lekarski 20040101 |
[Second neoplasm in a 13-year-old boy complicated by Crohn's disease. Case report]. | Medycyna wieku rozwojowego 20040101 |
Reduction of drug toxicity using dendrimers based on melamine. | Molecular pharmaceutics 20040101 |
[Immunosuppressive therapy of inflammatory diseases of the large intestine]. | Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20040101 |
Optimizing anti-tumor necrosis factor strategies in inflammatory bowel disease. | Current gastroenterology reports 20031201 |
Optimizing immunomodulator therapy for inflammatory bowel disease. | Current gastroenterology reports 20031201 |
Role of macrophages and stellate cells in the pathogenesis of veno-occlusive disease: an electron microscopic case study. | Experimental and molecular pathology 20031201 |
Study of ruthenium(II) complexes with anticancer drugs as ligands. Design of metal-based phototherapeutic agents. | Inorganic chemistry 20031201 |
Evidence-based treatment algorithm for mild to moderate Crohn's disease. | The American journal of gastroenterology 20031201 |
Maintenance therapy for inflammatory bowel disease. | The American journal of gastroenterology 20031201 |
Synthesis of base substituted 2-hydroxy-3-(purin-9-yl)-propanoic acids and 4-(purin-9-yl)-3-butenoic acids. | Nucleosides, nucleotides & nucleic acids 20031201 |
[Relationship between single nucleotide polymorphisms in thiopurine methyltransferase gene and tolerance to thiopurines in acute leukemia]. | Zhonghua er ke za zhi = Chinese journal of pediatrics 20031201 |
Fistula response to methotrexate in Crohn's disease: a case series. | Alimentary pharmacology & therapeutics 20031115 |
Spectroscopy behavior of 6-Mercaptopurine, Azathiopurine, and 8-Azaguanine. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20031101 |
Predictive factors of response of perianal Crohn's disease to azathioprine or 6-mercaptopurine. | Diseases of the colon and rectum 20031101 |
Protein expression of the glucocorticoid receptor in childhood acute lymphoblastic leukemia. | Haematologica 20031101 |
Discussion on the safety of 6-mercaptopurine for childbearing patients with inflammatory bowel disease: a retrospective cohort study. | Gastroenterology 20031101 |
Monitoring of AZA/6-MP treatment in children with IBD is necessary. | Inflammatory bowel diseases 20031101 |
Monitoring of azathioprine/6-mercaptopurine treatment in children with IBD is not necessary. | Inflammatory bowel diseases 20031101 |
6TG: when less is more than you bargained for. | Inflammatory bowel diseases 20031101 |
A novel Escherichia coli strain allows functional analysis of guanylate kinase drug resistance and sensitivity. | Analytical biochemistry 20031101 |
High-performance liquid chromatographic assay of metabolites of thioguanine and mercaptopurine in capillary blood. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031025 |
Tertiary structure of thiopurine methyltransferase from Pseudomonas syringae, a bacterial orthologue of a polymorphic, drug-metabolizing enzyme. | Journal of molecular biology 20031024 |
Preventing toxicity with a gene test. | Science (New York, N.Y.) 20031024 |
Drug methylation in cancer therapy: lessons from the TPMT polymorphism. | Oncogene 20031020 |
Thioguanine offers no advantage over mercaptopurine in maintenance treatment of childhood ALL: results of the randomized trial COALL-92. | Blood 20031015 |
Determination of thiopurine methyltransferase phenotype in isolated human erythrocytes using a new simple nonradioactive HPLC method. | Therapeutic drug monitoring 20031001 |
Veno-occlusive disease in patients receiving thiopurines during maintenance therapy for childhood acute lymphoblastic leukaemia. | British journal of haematology 20031001 |
Childhood T-cell acute lymphoblastic leukemia: the Dana-Farber Cancer Institute acute lymphoblastic leukemia consortium experience. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031001 |
[Juvenile myelomonocytic leukaemia, xanthoma, and neurofibromatosis type 1]. | Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20031001 |
Choice of chemotherapy in induction, consolidation and maintenance in acute promyelocytic leukaemia. | Best practice & research. Clinical haematology 20030901 |
Treatment of older adults with acute promyelocytic leukaemia. | Best practice & research. Clinical haematology 20030901 |
Cumulative experience with short- and long-term toxicity to 6-mercaptopurine in the treatment of Crohn's disease and ulcerative colitis. | Journal of clinical gastroenterology 20030901 |
Thiopurine S-methyltransferase pharmacogenetics: chaperone protein association and allozyme degradation. | Pharmacogenetics 20030901 |
[Acute myeloid leukemia originating from the same leukemia clone after the complete remission of acute lymphoid leukemia]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20030901 |
Thiopurine S-methyltransferase (TPMT) genotype does not predict adverse drug reactions to thiopurine drugs in patients with inflammatory bowel disease. | Alimentary pharmacology & therapeutics 20030815 |
Tioguanine in patients with Crohn's disease intolerant or resistant to azathioprine/mercaptopurine. | Alimentary pharmacology & therapeutics 20030815 |
Analysis of single nucleotide polymorphism C3435T of the multidrug resistance gene MDR1 in acute lymphoblastic leukemia. | International journal of oncology 20030801 |
Msh2 deficiency attenuates but does not abolish thiopurine hematopoietic toxicity in msh2-/- mice. | Molecular pharmacology 20030801 |
Leflunomide treatment of Crohn's disease patients intolerant to standard immunomodulator therapy. | Journal of clinical gastroenterology 20030801 |
Myelodysplastic syndrome after acute promyelocytic leukemia: the European APL group experience. | Leukemia 20030801 |
Corticosteroids and immunomodulators: postoperative infectious complication risk in inflammatory bowel disease patients. | Gastroenterology 20030801 |
6-mercaptopurine beats a bum rap. | Gastroenterology 20030801 |
Amperometric determination of 6-mercaptopurine on functionalized multi-wall carbon nanotubes modified electrode by liquid chromatography coupled with microdialysis and its application to pharmacokinetics in rabbit. | Talanta 20030727 |
High variation of tioguanine absorption in patients with chronic active Crohn's disease. | Alimentary pharmacology & therapeutics 20030715 |
Study of the interaction of 6-mercaptopurine with protein by microdialysis coupled with LC and electrochemical detection based on functionalized multi-wall carbon nanotubes modified electrode. | Journal of pharmaceutical and biomedical analysis 20030714 |
The AF-1 domain of the orphan nuclear receptor NOR-1 mediates trans-activation, coactivator recruitment, and activation by the purine anti-metabolite 6-mercaptopurine. | The Journal of biological chemistry 20030704 |
Identification of the antineoplastic agent 6-mercaptopurine as an activator of the orphan nuclear hormone receptor Nurr1. | The Journal of biological chemistry 20030704 |
Real-time RT-PCR methodology for quantification of thiopurine methyltransferase gene expression. | European journal of clinical pharmacology 20030701 |
Severe gastrointestinal illness associated with olestra ingestion. | Journal of pediatric gastroenterology and nutrition 20030701 |
Dose reduction of coadministered 6-mercaptopurine decreases myelotoxicity following high-dose methotrexate in childhood leukemia. | Leukemia 20030701 |
A novel TPMT missense mutation associated with TPMT deficiency in a 5-year-old boy with ALL. | Leukemia 20030701 |
[Molecular mechanisms of drug influx and efflux transport at the blood-brain barrier]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20030701 |
Severe isolated Crohn's-like disease of the gastroduodenal tract. | Digestive diseases and sciences 20030701 |
Genetic polymorphism of thiopurine S-methyltransferase in Argentina. | Annals of clinical biochemistry 20030701 |
Erythrocyte mean corpuscular volume as a surrogate marker for 6-thioguanine nucleotide concentration monitoring in patients with inflammatory bowel disease treated with azathioprine or 6-mercaptopurine. | Inflammatory bowel diseases 20030701 |
[Thiopurine methyltransferase activity and myelosuppression in inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurine]. | Medicina clinica 20030607 |
Hypersensitivity reactions to chemotherapeutic drugs. | Clinical reviews in allergy & immunology 20030601 |
Distinct tissue distribution of metabolites of the novel glutathione-activated thiopurine prodrugs cis-6-(2-acetylvinylthio)purine and trans-6-(2-acetylvinylthio)guanine and 6-thioguanine in the mouse. | Drug metabolism and disposition: the biological fate of chemicals 20030601 |
Review article: medical treatment of moderate to severe Crohn's disease. | Alimentary pharmacology & therapeutics 20030601 |
Review article: maintenance treatment of Crohn's disease. | Alimentary pharmacology & therapeutics 20030601 |
Antagonism by methotrexate on mercaptopurine disposition in lymphoblasts during up-front treatment of acute lymphoblastic leukemia. | Clinical pharmacology and therapeutics 20030601 |
Long-term survival in acute lymphoblastic leukaemia in adults treated according to the LALA 87 protocol. | Chemotherapy 20030601 |
Dexamethasone versus prednisone and daily oral versus weekly intravenous mercaptopurine for patients with standard-risk acute lymphoblastic leukemia: a report from the Children's Cancer Group. | Blood 20030515 |
The role of multidrug resistance protein 1 (MRP1) in transport of fluorescent anions across the human erythrocyte membrane. | The Journal of membrane biology 20030515 |
Treatment-specific changes in gene expression discriminate in vivo drug response in human leukemia cells. | Nature genetics 20030501 |
On-line monitoring of airborne chemistry in levitated nanodroplets: in situ synthesis and application of SERS-active Ag-Sols for trace analysis by FT-Raman spectroscopy. | Analytical chemistry 20030501 |
6-mercaptopurine and inflammatory bowel disease: hidden ground for the cytomegalovirus. | Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20030501 |
Thioguanine: a potential alternate thiopurine for IBD patients allergic to 6-mercaptopurine or azathioprine. | The American journal of gastroenterology 20030501 |
[Auto-immune hepatitis: therapeutic management]. | Gastroenterologie clinique et biologique 20030501 |
CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes. | The Journal of clinical investigation 20030415 |
Complications of pregnancy and child development after cessation of treatment with 6-mercaptopurine for inflammatory bowel disease. | Journal of clinical gastroenterology 20030401 |
Second malignant neoplasms after treatment of childhood cancer. | European journal of cancer (Oxford, England : 1990) 20030401 |
Intensification of mercaptopurine/methotrexate maintenance chemotherapy may increase the risk of relapse for some children with acute lymphoblastic leukemia. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030401 |
Rat organic anion transporter 3 (rOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20030401 |
Topical delivery of 5-fluorouracil and 6-mercaptopurine by their alkylcarbonyloxymethyl prodrugs from water: vehicle effects on design of prodrugs. | Pharmaceutical research 20030401 |
Cancer pharmacogenomics: current and future applications. | Biochimica et biophysica acta 20030317 |
Azathioprine, mercaptopurine and birth outcome: a population-based cohort study. | Alimentary pharmacology & therapeutics 20030315 |
Cytotoxic activity of 6-alkynyl- and 6-alkenylpurines. | Bioorganic & medicinal chemistry letters 20030310 |
Cell proliferation is related to in vitro drug resistance in childhood acute leukaemia. | British journal of cancer 20030310 |
High survival rate in childhood non-Hodgkin lymphoma without CNS involvement: results of BFM 95 study in Kuwait. | Pediatric hematology and oncology 20030301 |
Benign intracranial hypertension in association with acute lymphoblastic leukemia. | Pediatric hematology and oncology 20030301 |
Hepatotoxicity associated with 6-thioguanine therapy for Crohn's disease. | Journal of clinical gastroenterology 20030301 |
Recent advances in immunomodulation in the treatment of inflammatory bowel disease. | European journal of gastroenterology & hepatology 20030301 |
Thiopurine therapy: when to start and when to stop. | European journal of gastroenterology & hepatology 20030301 |
Ciclosporin and refractory colitis. | European journal of gastroenterology & hepatology 20030301 |
Successful reintroduction of methotrexate after acute pneumonitis in a patient with acute lymphoblastic leukemia. | Annals of hematology 20030301 |
Treatment of recurrent eosinophilic granuloma with systemic therapy. | Ophthalmic plastic and reconstructive surgery 20030301 |
First experience with intracytoplasmic sperm injection for extreme oligozoospermia associated with Crohn's disease and 6-mercaptopurine chemotherapy. | Asian journal of andrology 20030301 |
Low dose methotrexate in inflammatory bowel disease: current status and future directions. | The American journal of gastroenterology 20030301 |
Immunomodulators and 'on demand' therapy with infliximab in Crohn's disease: clinical experience with 400 infusions. | The American journal of gastroenterology 20030301 |
[Management of ulcerative colitis]. | Therapeutische Umschau. Revue therapeutique 20030301 |
Comparison of suppressive potency between azathioprine and 6-mercaptopurine against mitogen-induced blastogenesis of human peripheral blood mononuclear cells in-vitro. | The Journal of pharmacy and pharmacology 20030301 |
Position statement: immunomodulator therapy for inflammatory Bowel disease. | The Israel Medical Association journal : IMAJ 20030301 |
[Therapy of chronic inflammatory bowel diseases with azathioprine, 6-mercaptopurine and 6-thioguanine. Clinico-pharmacologic aspects]. | Deutsche medizinische Wochenschrift (1946) 20030221 |
6-thioguanine--efficacy and safety in chronic active Crohn's disease. | Alimentary pharmacology & therapeutics 20030215 |
Effective drug delivery by PEGylated drug conjugates. | Advanced drug delivery reviews 20030210 |
Cyclosporin for refractory ulcerative colitis. | Gut 20030201 |
Diminished anticoagulant effects of warfarin with concomitant mercaptopurine therapy. | Pharmacotherapy 20030201 |
Optimizing treatment with thioguanine derivatives in inflammatory bowel disease. | Best practice & research. Clinical gastroenterology 20030201 |
Safe treatment of thiopurine S-methyltransferase deficient Crohn's disease patients with azathioprine. | Gut 20030101 |
Dental abnormalities in children after chemotherapy treatment for acute lymphoid leukemia. | Leukemia research 20030101 |
Unlicensed and off label drug use in acute lymphoblastic leukaemia and other malignancies in children. | Annals of oncology : official journal of the European Society for Medical Oncology 20030101 |
Review article: immunopathogenetic and therapeutic aspects of autoimmune hepatitis. | Alimentary pharmacology & therapeutics 20030101 |
Mercaptopurine metabolite results in clinical gastroenterology practice. | Alimentary pharmacology & therapeutics 20030101 |
Is thiopurine methyltransferase genetic polymorphism a major factor for withdrawal of azathioprine in rheumatoid arthritis patients? | Rheumatology (Oxford, England) 20030101 |
The safety of 6-mercaptopurine for childbearing patients with inflammatory bowel disease: a retrospective cohort study. | Gastroenterology 20030101 |
Application of pharmacokinetic/pharmacodynamic and stochastic modelling to 6-mercaptopurine micronucleus induction in mouse bone marrow erythrocytes. | Journal of applied toxicology : JAT 20030101 |
[Invasive cancer of the cervix in a patient undergoing chronic treatment with 6-mercaptopurine for Crohns disease]. | Gastroenterologia y hepatologia 20030101 |
Azathioprine and anti-TNF alpha therapies in Crohn's disease: a review of pharmacology, clinical efficacy and safety. | Pharmacological research 20030101 |
[Acute episode]. | Zeitschrift fur Gastroenterologie 20030101 |
[Chronically active Crohn's disease]. | Zeitschrift fur Gastroenterologie 20030101 |
[Maintaining a remission]. | Zeitschrift fur Gastroenterologie 20030101 |
Combination therapy in childhood leukaemia: in vitro studies of thiopurines and inhibitors of purine metabolism on apoptosis. | Annals of clinical biochemistry 20030101 |
Measurement of thiopurine S-methyltransferase activity in human blood samples based on high-performance liquid chromatography: reference values in erythrocytes from children. | Annals of clinical biochemistry 20030101 |
6-Thioguanine seems promising in azathioprine- or 6-mercaptopurine-intolerant inflammatory bowel disease patients: a short-term safety assessment. | European journal of gastroenterology & hepatology 20030101 |
[Inflammatory bowel diseases (IBD) -- critical discussion of etiology, pathogenesis, diagnostics, and therapy]. | Der Radiologe 20030101 |
Investigation of the mechanisms of therapy-related hypoglycaemia in children with acute lymphoblastic leukaemia. | Acta paediatrica (Oslo, Norway : 1992) 20030101 |
Treatment of inflammatory bowel disease in childhood: best available evidence. | Inflammatory bowel diseases 20030101 |
[Significance of TPMT activity and TGNs level detection for individualizing 6-mercaptopurine chemotherapy]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20030101 |
Therapeutic efficacy and safety of 6-mercaptopurine and azathioprine in patients with Crohn's disease. | Reviews in gastroenterological disorders 20030101 |
Clinical use and practical application of TPMT enzyme and 6-mercaptopurine metabolite monitoring in IBD. | Reviews in gastroenterological disorders 20030101 |
Optimizing the therapeutic potential of azathioprine/6-mercaptopurine in the treatment of inflammatory bowel disease. | Journal of clinical gastroenterology 20030101 |
Utility of measuring 6-methylmercaptopurine and 6-thioguanine nucleotide levels in managing inflammatory bowel disease patients treated with 6-mercaptopurine in a clinical practice setting. | Journal of clinical gastroenterology 20030101 |
The yeast ISN1 (YOR155c) gene encodes a new type of IMP-specific 5'-nucleotidase. | BMC biochemistry 20030101 |
Optimization and individualization of thiopurine therapy in inflammatory bowel disease: the great variability among drug responses. | The pharmacogenomics journal 20030101 |
Cytokine and anti-cytokine therapies for inflammatory bowel disease. | Current pharmaceutical design 20030101 |
The state of the art in the management of inflammatory bowel disease. | Reviews in gastroenterological disorders 20030101 |
A national survey on the patterns of treatment of inflammatory bowel disease in Canada. | BMC gastroenterology 20030101 |
[Does conservative therapy of chronic inflammatory bowel diseases still play a role?]. | Swiss surgery = Schweizer Chirurgie = Chirurgie suisse = Chirurgia svizzera 20030101 |
Wegener's granulomatosis: current and upcoming therapies. | Arthritis research & therapy 20030101 |
[The assessment of plasma levels of insulin-like growth factor (IGF-I) and binding protein (IGFBP-3) during the maintenance therapy and after remissionof acute lymphoblastic leukemia (ALL)]. | Endokrynologia, diabetologia i choroby przemiany materii wieku rozwojowego : organ Polskiego Towarzystwa Endokrynologow Dzieciecych 20030101 |
[The influence of age, gender and modifications of therapeutic protocols on physical development of children and adolescents after completion of therapy for acute lymphoblastic leukemia]. | Endokrynologia, diabetologia i choroby przemiany materii wieku rozwojowego : organ Polskiego Towarzystwa Endokrynologow Dzieciecych 20030101 |
A case of leukemia of the appendix presenting as acute appendicitis. | Acta haematologica 20030101 |
Laparoscopic management of complex Crohn's disease. | JSLS : Journal of the Society of Laparoendoscopic Surgeons 20030101 |
Role of red blood cells in pharmacokinetics of chemotherapeutic agents. | Clinical pharmacokinetics 20030101 |
Comparison of the effects of azathioprine and its novel non-mercaptopurine analog on antibody response in rabbits. | Polish journal of pharmacology 20030101 |
Allelic variants of the thiopurine methyltransferase (TPMT) gene in the Colombian population. | Methods and findings in experimental and clinical pharmacology 20030101 |
Pharmacogenomics of azathioprine and 6-mercaptopurine in gastroenterologic therapy. | Reviews in gastroenterological disorders 20030101 |
Low-dose azathioprine is effective and safe for maintenance of remission in patients with ulcerative colitis. | Journal of gastroenterology 20030101 |
Role and side-effects of TPMT polymorphisms of 6-MP and azathioprine in the treatment of steroid-resistant and -dependent ulcerative colitis. | Journal of gastroenterology 20030101 |
[Improved results in children with acute lymphoblastic leukemia treated with the ALL-BFM 90 protocol in the Czech Republic]. | Casopis lekaru ceskych 20030101 |
Thioguanine, mercaptopurine: their analogs and nucleosides as antimetabolites. | Current pharmaceutical design 20030101 |
Cancer pharmacogenomics: SNPs, chips, and the individual patient. | Cancer investigation 20030101 |
Standard treatment of ulcerative colitis. | Digestive diseases (Basel, Switzerland) 20030101 |
Pediatric acute lymphoblastic leukemia. | Hematology. American Society of Hematology. Education Program 20030101 |
Azathioprine as a treatment for severe atopic eczema in children with a partial thiopurine methyl transferase (TPMT) deficiency. | Pediatric dermatology 20030101 |
Bioequivalence of azathioprine products. | Reviews in gastroenterological disorders 20030101 |
Comparative kinetics of azathioprine and metazathioprine mercaptolysis in presence of physiological thiols. | Acta poloniae pharmaceutica 20030101 |
Safety of thiopurines in the treatment of inflammatory bowel disease. | Scandinavian journal of gastroenterology. Supplement 20030101 |
[Efficacy of medical therapy in preventing the post-surgical recurrence in Crohn's disease]. | Annali italiani di chirurgia 20030101 |
[Conservative therapy of inflammatory bowel diseases]. | Orvosi hetilap 20021215 |
Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells. | Molecular pharmacology 20021201 |
Evolving medical therapies for ulcerative colitis. | Current gastroenterology reports 20021201 |
Advances in medical therapy for Crohn's disease. | Current gastroenterology reports 20021201 |
Infliximab in the treatment of Crohn's disease: a user's guide for clinicians. | The American journal of gastroenterology 20021201 |
Induction therapy with idarubicin alone significantly influences event-free survival duration in patients with newly diagnosed hypergranular acute promyelocytic leukemia: final results of the GIMEMA randomized study LAP 0389 with 7 years of minimal follow-up. | Blood 20021101 |
Improvement over time in outcome for children with acute lymphoblastic leukemia in second remission given hematopoietic stem cell transplantation from unrelated donors. | Leukemia 20021101 |
Appendectomy protects against the development of ulcerative colitis but does not affect its course. | The American journal of gastroenterology 20021101 |
Inhibitors of de novo nucleotide biosynthesis as drugs. | Accounts of chemical research 20021101 |
Methotrexate polyglutamation may lack prognostic significance in children with B-cell precursor acute lymphoblastic leukemia treated with intensive oral methotrexate. | Journal of pediatric hematology/oncology 20021101 |
Severe pancytopenia from thiopurine methyltransferase deficiency: a preventable complication of 6-mercaptopurine therapy in children with Crohn disease. | Journal of pediatric gastroenterology and nutrition 20021101 |
The glutathione-activated thiopurine prodrugs trans-6-(2-acetylvinylthio)guanine and cis-6-(2-acetylvinylthio)purine cause less in vivo toxicity than 6-thioguanine after single- and multiple-dose regimens. | Molecular cancer therapeutics 20021101 |
Recent developments in inflammatory bowel disease. | The Medical clinics of North America 20021101 |
Oral cancer treatment: developments in chemotherapy and beyond. | British journal of cancer 20021021 |
[Resistance to tumor specific therapy with imatinib by clonal selection of mutated cells]. | Deutsche medizinische Wochenschrift (1946) 20021018 |
Drug side-effects in IBD. | Alimentary pharmacology & therapeutics 20021001 |
Role of blood-brain barrier organic anion transporter 3 (OAT3) in the efflux of indoxyl sulfate, a uremic toxin: its involvement in neurotransmitter metabolite clearance from the brain. | Journal of neurochemistry 20021001 |
[Individualized therapy with azathioprine or 6-mercaptopurine by monitoring thiopurine methyl-transferase (TPMT) activity]. | Revista clinica espanola 20021001 |
[Pharmacogenetic study of thiopurine S-methyltransferase (TPMT) and thiopurine toxicity]. | Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 20021001 |
Determination of thiols in urinary sample by capillary-column liquid chromatography with amperometric detection at a carbon electrode. | Talanta 20020912 |
Loss of heterozygosity of p16 correlates with minimal residual disease at the end of the induction therapy in non-high risk childhood B-cell precursor acute lymphoblastic leukemia. | Leukemia research 20020901 |
Thiopurine S-methyltransferase activity in Japanese subjects: metabolic activity of 6-mercaptopurine 6-methylation in different TPMT genotypes. | Clinica chimica acta; international journal of clinical chemistry 20020901 |
The role of posttransplantation maintenance chemotherapy in improving the outcome of autotransplantation in adult acute lymphoblastic leukemia. | Blood 20020901 |
Therapy-related myelodysplastic syndrome or acute myelogenous leukemia in patients with acute promyelocytic leukemia (APL). | Leukemia 20020901 |
Simple chemiluminescence method for the determination of mercaptopurine. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20020901 |
Spectrophotometric determination of biologically active thiols with eosin, silver(I) and adenine. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20020901 |
6-Mercaptopurine teratogenicity. | Postgraduate medical journal 20020901 |
Biologic and molecular mechanisms for sex differences in pharmacokinetics, pharmacodynamics, and pharmacogenetics: Part I. | Journal of women's health & gender-based medicine 20020901 |
Azathioprine or 6-mercaptopurine before colectomy for ulcerative colitis is not associated with increased postoperative complications. | Inflammatory bowel diseases 20020901 |
Ex vivo drug resistance profile in childhood acute myelogenous leukemia: no drug is more effective in comparison to acute lymphoblastic leukemia. | Leukemia & lymphoma 20020901 |
Use of the photo-micronucleus assay in Chinese hamster V79 cells to study photochemical genotoxicity. | Mutation research 20020826 |
De novo purine synthesis inhibition and antileukemic effects of mercaptopurine alone or in combination with methotrexate in vivo. | Blood 20020815 |
TPMT in the treatment of Crohn's disease with azathioprine. | Gut 20020801 |
Protagonist: Crohn's disease recurrence can be prevented after ileal resection. | Gut 20020801 |
Immunosuppressants and operation in ulcerative colitis. | Journal of the American College of Surgeons 20020801 |
Azathioprine therapy and adverse drug reactions in patients with inflammatory bowel disease: impact of thiopurine S-methyltransferase polymorphism. | Pharmacogenetics 20020801 |
Combining infliximab with 6-mercaptopurine/azathioprine for fistula therapy in Crohn's disease. | The American journal of gastroenterology 20020801 |
[Progress in the field of hematology in the last 100 years: Medical history of acute leukemia]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20020710 |
CD56 expression predicts occurrence of CNS disease in acute lymphoblastic leukemia. | Leukemia research 20020701 |
Review article: treatment of mild to moderate ulcerative colitis and pouchitis. | Alimentary pharmacology & therapeutics 20020701 |
Review article: maintenance of remission in ulcerative colitis. | Alimentary pharmacology & therapeutics 20020701 |
Review article: the management of refractory Crohn's disease. | Alimentary pharmacology & therapeutics 20020701 |
The effect of thiopurine methyltransferase expression on sensitivity to thiopurine drugs. | Molecular pharmacology 20020701 |
Leucocyte versus erythrocyte thioguanine nucleotide concentrations in children taking thiopurines for acute lymphoblastic leukaemia. | Cancer chemotherapy and pharmacology 20020701 |
Symptomatic hypoglycemia in children receiving oral purine analogues for treatment of childhood acute lymphoblastic leukemia. | Medical and pediatric oncology 20020701 |
Variant translocations of 11q23 in infant acute lymphoblastic leukemia (ALL): do outcomes differ from t(4;11)? | Medical and pediatric oncology 20020701 |
Increased factor VIII activity and dural sinus thrombosis. | Medical and pediatric oncology 20020701 |
Infliximab improves quality of life in patients with Crohn's disease. | Inflammatory bowel diseases 20020701 |
Corticosteroid-sparing treatments in patients with Crohn's disease. | The American journal of gastroenterology 20020701 |
[Development of simplified and rapid detection assay for genetic polymorphisms influencing drug response and its clinical applications]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20020701 |
Advances in the medical therapy of inflammatory bowel disease. | Current opinion in gastroenterology 20020701 |
Thiopurine methyltransferase activity: new conditions for reversed-phase high-performance liquid chromatographic assay without extraction and genotypic-phenotypic correlation. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020625 |
Impact of addition of maintenance therapy to intensive induction and consolidation chemotherapy for childhood acute myeloblastic leukemia: results of a prospective randomized trial, LAME 89/91. Leucámie Aiqüe Myéloïde Enfant. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020615 |
Differences between children and adults in thiopurine methyltransferase activity and metabolite formation during thiopurine therapy: possible role of concomitant methotrexate. | Therapeutic drug monitoring 20020601 |
BFM-oriented treatment for children with acute lymphoblastic leukemia without cranial irradiation and treatment reduction for standard risk patients: results of DCLSG protocol ALL-8 (1991-1996). | Leukemia 20020601 |
Recurrence of Langerhans cell histiocytosis in the graft after liver transplantation in adults. | Transplantation proceedings 20020601 |
Forecast for using metabolite measurements in the dosing of azathioprine or 6-mercaptopurine for IBD patients: 'partly cloudy'. | Gastroenterology 20020601 |
Cytotoxic effects of 27 anticancer drugs in HeLa and MDR1-overexpressing derivative cell lines. | Biological & pharmaceutical bulletin 20020601 |
[When is drug therapy with azathioprine indicated in Crohn's disease?]. | Deutsche medizinische Wochenschrift (1946) 20020531 |
Intensified and shortened cyclical chemotherapy for adult acute lymphoblastic leukemia. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020515 |
Review article: is clinical remission the optimum therapeutic goal in the treatment of Crohn's disease? | Alimentary pharmacology & therapeutics 20020501 |
Teratogen update: azathioprine and 6-mercaptopurine. | Teratology 20020501 |
Modulation of colony stimulating factor release and apoptosis in human colon cancer cells by anticancer drugs. | British journal of cancer 20020422 |
Novel glutathione-dependent thiopurine prodrugs: evidence for enhanced cytotoxicity in tumor cells and for decreased bone marrow toxicity in mice. | The Journal of pharmacology and experimental therapeutics 20020401 |
6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease. | Gastroenterology 20020401 |
Review article: monitoring for drug side-effects in inflammatory bowel disease. | Alimentary pharmacology & therapeutics 20020401 |
Determination of thiopurine S-methyltransferase phenotype using thin-layer chromatography and quantitative scanning. | European journal of clinical pharmacology 20020401 |
Burkitt's lymphoma: single-centre experience with modified BFM protocol. | Clinical and laboratory haematology 20020401 |
Immunomodulatory therapy for pediatric inflammatory bowel disease: changing patterns of use, 1990-2000. | The American journal of gastroenterology 20020401 |
The role of drug efflux pumps in acute myeloid leukemia. | Leukemia & lymphoma 20020401 |
Management of internal fistulas in Crohn's disease. | Inflammatory bowel diseases 20020301 |
The Children Leukemia Group: 30 years of research and achievements. | European journal of cancer (Oxford, England : 1990) 20020301 |
Randomized, controlled trial of recombinant human interleukin-11 in patients with active Crohn's disease. | Alimentary pharmacology & therapeutics 20020301 |
Pharmacological characterization of the ATP-dependent low K(m) guanosine 3',5'-cyclic monophosphate (cGMP) transporter in human erythrocytes. | Biochemical pharmacology 20020301 |
[Treatment of acute lymphoblastic leukemia in adults with seven-drug induction therapy and intensive consolidation with or without autologous stem cell transplantation followed by maintenance therapy. Experience of a single center]. | Casopis lekaru ceskych 20020301 |
Successful treatment of postoperative pyoderma gangrenosum with cyclosporin. | Journal of the European Academy of Dermatology and Venereology : JEADV 20020301 |
Inflammatory bowel disease in the pediatric and adolescent patient. | Gastroenterology clinics of North America 20020301 |
Cytotoxic and antibacterial activity of 2-oxopurine derivatives. | Bioorganic & medicinal chemistry letters 20020225 |
Prognostic significance of the null genotype of glutathione S-transferase-T1 in patients with acute myeloid leukemia: increased early death after chemotherapy. | Leukemia 20020201 |
Effect of methotrexate polyglutamates on thioguanine nucleotide concentrations during continuation therapy of acute lymphoblastic leukemia with mercaptopurine. | Leukemia 20020201 |
Review article: Immunosuppressants in distal ulcerative colitis. | Alimentary pharmacology & therapeutics 20020201 |
No major cognitive impairment in young children with acute lymphoblastic leukemia using chemotherapy only: a prospective longitudinal study. | Journal of pediatric hematology/oncology 20020201 |
HPLC determination of thiopurine nucleosides and nucleotides in vivo in lymphoblasts following mercaptopurine therapy. | Clinical chemistry 20020101 |
Management of growth retardation in the young patient with Crohn's disease. | Expert opinion on pharmacotherapy 20020101 |
Epstein-Barr virus-positive lymphoma in patients with inflammatory bowel disease treated with azathioprine or 6-mercaptopurine. | Gastroenterology 20020101 |
Recurrent mercaptopurine-induced acute pancreatitis: a rare complication of chemotherapy for acute lymphoblastic leukemia in children. | Medical and pediatric oncology 20020101 |
Prognosis of elderly patients with acute myelogenous leukemia: analysis of 126 AML cases. | International journal of hematology 20020101 |
Philadelphia chromosome-positive acute myeloid leukemia with tetraploidy. | International journal of hematology 20020101 |
Results of a randomized phase III trial in children and adolescents with advanced stage diffuse large cell non-Hodgkin's lymphoma: a Pediatric Oncology Group study. | Leukemia & lymphoma 20020101 |
Pentasomy 8q resulting from duplication of isochromosome 8q in chronic myelomonocytic leukemia. | Leukemia & lymphoma 20020101 |
The thiopurine S-methyltransferase gene locus -- implications for clinical pharmacogenomics. | Pharmacogenomics 20020101 |
Pharmacogenetics: has it reached the clinic? | The journal of gender-specific medicine : JGSM : the official journal of the Partnership for Women's Health at Columbia 20020101 |
Intermediate-dose methotrexate and intravenous 6-mercaptopurine chemotherapy for children with acute lymphoblastic leukemia who did not respond to initial induction therapy. | Journal of pediatric hematology/oncology 20020101 |
Do immunosuppressants really work as maintenance therapy after the achievement of remission of severe ulcerative colitis? | Journal of gastroenterology 20020101 |
[Questions and answers on the role of azathioprine and 6-mercaptopurine in the treatment of inflammatory bowel disease]. | Gastroenterologia y hepatologia 20020101 |
Food-drug interactions. | Drugs 20020101 |
Treatment of inflammatory bowel disease in the elderly: an update. | Drugs & aging 20020101 |
Comparative tolerability of therapies for ulcerative colitis. | Drug safety 20020101 |
Thiopurine methyltransferase polymorphisms in a multiracial asian population and children with acute lymphoblastic leukemia. | Journal of pediatric hematology/oncology 20020101 |
CD7+ and CD56+ myeloid/natural killer cell precursor acute leukemia treated with idarubicin and cytosine arabinoside. | Acta haematologica 20020101 |
Immunosuppressive treatment of Crohn's disease with fistulae. | Bratislavske lekarske listy 20020101 |
Ulcerative colitis in children: medical management. | Paediatric drugs 20020101 |
Preconcentration and separation of copper, zinc and cadmium by the use of 6-mercapto purinylazo resin and their application in microwave digested certified biological samples followed by AAS determination of the metal ions. | Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20020101 |
[Results of the treatment of childhood acute lymphoblastic leukemia according to the Berlin-Moscow-91 protocol in 1991-2000]. | Voprosy onkologii 20020101 |
The combined effects of antibacterial peptide cecropin A and anti-cancer agents on leukemia cells. | Anticancer research 20020101 |
Evolving medical therapies for ulcerative colitis. | Current gastroenterology reports 20011201 |
Comparative pharmacokinetics of oral 6-mercaptopurine and intravenous 6-mercaptopurine riboside in children. | Pediatrics international : official journal of the Japan Pediatric Society 20011201 |
Mechanism of azathioprine-induced injury to hepatocytes: roles of glutathione depletion and mitochondrial injury. | Journal of hepatology 20011201 |
Why measure thiopurine methyltransferase activity? Direct administration of 6-thioguanine might be the alternative for 6-mercaptopurine or azathioprine. | Gut 20011201 |
Avoidance of steroids by the early use of infliximab and 6-mercaptopurine in an adolescent with active Crohn's colitis. | The American journal of gastroenterology 20011201 |
Randomized, double-blind, crossover, placebo-controlled trial of intravenous ondansetron for the prevention of intrathecal chemotherapy-induced vomiting in children. | Journal of pediatric hematology/oncology 20011201 |
Successful treatment of refractory Langerhans cell histiocytosis with unrelated cord blood transplantation. | Journal of pediatric hematology/oncology 20011201 |
Unrelated cord blood transplantation for an infant with chemotherapy-resistant progressive Langerhans cell histiocytosis. | Journal of pediatric hematology/oncology 20011201 |
Continuing therapy for childhood acute lymphoblastic leukaemia: clinical and cellular pharmacology of methotrexate, 6-mercaptopurine and 6-thioguanine. | Cancer treatment reviews 20011201 |
Diagnosis and treatment of perianal fistulas in Crohn disease. | Annals of internal medicine 20011120 |
In vitro bioassays for anticancer drug screening: effects of cell concentration and other assay parameters on growth inhibitory activity. | Cancer letters 20011108 |
Leucopenia resulting from a drug interaction between azathioprine or 6-mercaptopurine and mesalamine, sulphasalazine, or balsalazide. | Gut 20011101 |
Measurement of thiopurine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease. | Gut 20011101 |
Azathioprine treatment and male fertility in inflammatory bowel disease. | Gastroenterology 20011101 |
Possible implication of thiopurine S-methyltransferase in occurrence of infectious episodes during maintenance therapy for childhood lymphoblastic leukemia with mercaptopurine. | Leukemia 20011101 |
Pitfalls in the determination of mutant alleles of the thiopurine methyltransferase gene. | Leukemia 20011101 |
Review article: the treatment of inflammatory bowel disease with 6-mercaptopurine or azathioprine. | Alimentary pharmacology & therapeutics 20011101 |
Azathioprine for prevention of postoperative recurrence in Crohn's disease. | European journal of gastroenterology & hepatology 20011101 |
Management of fistulas in patients with Crohn's disease: antibiotic to antibody. | Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20011101 |
Cytostatic activity of Achillea ageratum L. | Phytotherapy research : PTR 20011101 |
Langerhans cell histiocytosis. | The Australasian journal of dermatology 20011101 |
Review article: the limitations of corticosteroid therapy in Crohn's disease. | Alimentary pharmacology & therapeutics 20011001 |
Determination of thiopurine methyltransferase activity in human erythrocytes by high-performance liquid chromatography: comparison with the radiochemical method. | Therapeutic drug monitoring 20011001 |
6-mercaptopurine metabolite levels in children with inflammatory bowel disease. | Journal of pediatric gastroenterology and nutrition 20011001 |
A variant form of acute promyelocytic leukemia with marked myelofibrosis. | International journal of hematology 20011001 |
Managing the glucocorticoid dependent inflammatory bowel disease patient. | Seminars in gastrointestinal disease 20011001 |
Medical management of ulcerative proctitis, proctosigmoiditis, and left-sided colitis. | Seminars in gastrointestinal disease 20011001 |
Modified cyclophosphamide, hydroxydaunorubicin, vincristine, and prednisone therapy for posttransplantation lymphoproliferative disease in pediatric patients undergoing solid organ transplantation. | Journal of pediatric hematology/oncology 20011001 |
Development of obesity and neurochemical backing in aurothioglucose-treated mice. | Autonomic neuroscience : basic & clinical 20010917 |
Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine. | The Journal of biological chemistry 20010907 |
Deoxythioguanosine triphosphate impairs HIV replication: a new mechanism for an old drug. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010901 |
Therapeutic drug monitoring of cytotoxic drugs. | British journal of clinical pharmacology 20010901 |
Neutropenia is not required for clinical remission during azathioprine therapy in inflammatory bowel disease. | European journal of gastroenterology & hepatology 20010901 |
Use of azathioprine or 6-mercaptopurine for treatment of steroid-dependent lymphocytic and collagenous colitis. | The American journal of gastroenterology 20010901 |
Therapy-related CD7+ acute myeloid leukemia with trisomy 8 following acute monocytic leukemia. | Anti-cancer drugs 20010901 |
Single-agent therapy with oral mercaptopurine for nonlymphoid blast crisis of chronic myeloid leukemia. | Annals of hematology 20010901 |
Long-term follow-up of the clinical efficacy of chemotherapy for acute myeloid leukemia at a single institute. | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20010901 |
Review article: the risk of lymphoma associated with inflammatory bowel disease and immunosuppressive treatment. | Alimentary pharmacology & therapeutics 20010801 |
Glucocorticoids and IL-10, but not 6-MP, 5-ASA or sulfasalazine block endothelial expression of MAdCAM-1: implications for inflammatory bowel disease therapy. | Alimentary pharmacology & therapeutics 20010801 |
[Metastatic Crohn's disease in childhood]. | Anales espanoles de pediatria 20010801 |
Differing contribution of thiopurine methyltransferase to mercaptopurine versus thioguanine effects in human leukemic cells. | Cancer research 20010801 |
An open-label pilot study using thioguanine as a therapeutic alternative in Crohn's disease patients resistant to 6-mercaptopurine therapy. | Inflammatory bowel diseases 20010801 |
6-Thioguanine: a naked bullet? (Or how pharmacogenomics can make old drugs brand new). | Inflammatory bowel diseases 20010801 |
Reversal of cytosine arabinoside (ara-C) resistance by the synergistic combination of 6-thioguanine plus ara-C plus PEG-asparaginase (TGAP) in human leukemia lines lacking or expressing p53 protein. | Cancer chemotherapy and pharmacology 20010801 |
Photoactivation of DNA thiobases as a potential novel therapeutic option. | Current biology : CB 20010724 |
Antimycobacterial activity of 9-sulfonylated/sulfenylated-6-mercaptopurine derivatives. | Bioorganic & medicinal chemistry letters 20010709 |
Mechanism of activation of an immunosuppressive drug: azathioprine. Quantum chemical study on the reaction of azathioprine with cysteine. | Journal of the American Chemical Society 20010704 |
A comparison of early intensive methotrexate/mercaptopurine with early intensive alternating combination chemotherapy for high-risk B-precursor acute lymphoblastic leukemia: a Pediatric Oncology Group phase III randomized trial. | Leukemia 20010701 |
Outcome of acute lymphoblastic leukemia in children with AL90 regimen: impact of response to treatment and sex difference on prognostic factors. | Medical and pediatric oncology 20010701 |
If at first you don't succeed...Try again? | The American journal of gastroenterology 20010701 |
Azathioprine for atopic dermatitis. | Clinical and experimental dermatology 20010701 |
Treatment of acute promyelocytic leukaemia using a combination of all-trans retinoic acid and chemotherapy. | Annals of the Academy of Medicine, Singapore 20010701 |
Involvement of the NUP98 gene in a chromosomal translocation t(11;20)(p15;q11.2) in a patient with acute monocytic leukemia (FAB-M5b). | International journal of hematology 20010701 |
Repetitious appearance and disappearance of different kinds of clonal cytogenetic abnormalities after allogeneic bone marrow transplantation. | International journal of hematology 20010701 |
Pneumococcal arthritis affects performance status in patients with chronic GVHD of the skin following allogeneic bone marrow transplantation. | International journal of hematology 20010701 |
Prognostic impact of CD45 antigen expression in high-risk, childhood B-cell precursor acute lymphoblastic leukemia. | Leukemia & lymphoma 20010701 |
Results of a randomized phase III trial in children and adolescents with advanced stage diffuse large cell non Hodgkin's lymphoma: a Pediatric Oncology Group study. | Leukemia & lymphoma 20010701 |
Pediatric inflammatory bowel disease: clinical and therapeutic aspects. | Current opinion in gastroenterology 20010701 |
Improved methods for determining the concentration of 6-thioguanine nucleotides and 6-methylmercaptopurine nucleotides in blood. | Journal of chromatography. B, Biomedical sciences and applications 20010605 |
6-Mercaptopurine for children newly diagnosed with Crohn's disease. | Current gastroenterology reports 20010601 |
Cost-utility of initial medical management for Crohn's disease perianal fistulae. | Gastroenterology 20010601 |
Magnetic resonance imaging detection of avascular necrosis of the bone in children receiving intensive prednisone therapy for acute lymphoblastic leukemia or non-Hodgkin lymphoma. | Leukemia 20010601 |
Rational dosing of azathioprine and 6-mercaptopurine. | Gut 20010501 |
Utilisation of erythrocyte 6-thioguanine metabolite levels to optimise azathioprine therapy in patients with inflammatory bowel disease. | Gut 20010501 |
Treatment of refractory microscopic colitis with azathioprine and 6-mercaptopurine. | Gastroenterology 20010501 |
Conventional treatment of Crohn's disease: objectives and outcomes. | Inflammatory bowel diseases 20010501 |
Approach to corticosteroid-dependent and corticosteroid-refractory Crohn's disease. | Inflammatory bowel diseases 20010501 |
Crohn's disease of the esophagus: clinical features and outcomes. | Inflammatory bowel diseases 20010501 |
Treatment of childhood acute lymphoblastic leukemia. Long-term results of the AIEOP-ALL 87 study. | Haematologica 20010501 |
Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010415 |
Hepatic dysfunction in children with acute lymphoblastic leukemia in remission: relation to hepatitis infection. | Medical and pediatric oncology 20010401 |
Genetic polymorphisms of thiopurine S-methyltransferase and 6-mercaptopurine toxicity in Japanese children with acute lymphoblastic leukaemia. | Pharmacogenetics 20010401 |
Allelotype frequency of the thiopurine methyltransferase (TPMT) gene in Japanese. | Pharmacogenetics 20010401 |
Thiopurine methyltransferase activity in the Jewish population of Israel. | European journal of clinical pharmacology 20010401 |
Genotype-phenotype correlation for thiopurine S-methyltransferase in healthy Italian subjects. | European journal of clinical pharmacology 20010401 |
Effect of the glutathione/glutathione disulfide redox couple on thiopurine methyltransferase. | Biochemical pharmacology 20010315 |
High-throughput genotyping of thiopurine S-methyltransferase by denaturing HPLC. | Clinical chemistry 20010301 |
Fasting hypoglycemia is common during maintenance therapy for childhood acute lymphoblastic leukemia. | The Journal of pediatrics 20010301 |
Plasma pharmacokinetics and cerebrospinal fluid penetration of thioguanine in children with acute lymphoblastic leukemia: a collaborative Pediatric Oncology Branch, NCI, and Children's Cancer Group study. | Cancer chemotherapy and pharmacology 20010301 |
A novel protein complex distinct from mismatch repair binds thioguanylated DNA. | Molecular pharmacology 20010201 |
Testicular relapse in acute promyelocytic leukaemia. | British journal of haematology 20010201 |
Tautomerism and infrared spectra of 2-thiopurine: an experimental matrix isolation and theoretical ab initio and density functional theory study. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20010201 |
Hepatic dysfunction as the presenting feature of acute lymphoblastic leukemia. | Journal of pediatric hematology/oncology 20010201 |
Smooth muscle tumor developing in an immunocompromised child after therapy for leukemia. | Journal of pediatric hematology/oncology 20010201 |
Tumor lysis syndrome in an infant with Langerhans cell histiocytosis successfully treated using continuous arteriovenous hemofiltration. | Journal of pediatric hematology/oncology 20010201 |
Intravenous cyclosporine in refractory pyoderma gangrenosum complicating inflammatory bowel disease. | Inflammatory bowel diseases 20010201 |
New developments in the immunosuppressive drug monitoring of cyclosporine, tacrolimus, and azathioprine. | Clinical biochemistry 20010201 |
Induction therapy of adult acute lymphocytic leukemia without the use of vincristine or prednisone. | Hematology/oncology clinics of North America 20010201 |
A multicenter trial of 6-mercaptopurine and prednisone in children with newly diagnosed Crohn disease. | Journal of pediatric gastroenterology and nutrition 20010201 |
Langerhans' cell histiocytosis presenting with a para-aortic lesion and heart failure. | Journal of the Formosan Medical Association = Taiwan yi zhi 20010201 |
New bioactive sulfated metabolites from the Mediterranean tunicate Sidnyum turbinatum. | Journal of natural products 20010201 |
The use of denaturing high-pressure liquid chromatography for the detection of mutations in thiopurine methyltransferase. | Journal of biochemical and biophysical methods 20010130 |
Long-term results of TPMT activity monitoring in azathioprine-treated renal allograft recipients. | Journal of the American Society of Nephrology : JASN 20010101 |
Stochastic modeling in toxicokinetics. Application to the in vivo micronucleus assay. | Mathematical biosciences 20010101 |
De novo acute myeloid leukemia in the elderly; a consistent fraction of long-term survivors by standard-dose chemotherapy. | Leukemia research 20010101 |
Molecular dynamics of DNA quadruplex molecules containing inosine, 6-thioguanine and 6-thiopurine. | Biophysical journal 20010101 |
Frequency of use and standards of care for the use of azathioprine and 6-mercaptopurine in the treatment of inflammatory bowel disease: a systematic review of the literature and a survey of Canadian gastroenterologists. | Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20010101 |
WAGR syndrome in a baby--the result of 6-MP treatment in a father affected by Crohn's disease? | The American journal of gastroenterology 20010101 |
Further evidence that 6-MP taken by the father with IBD provides risk of congenital anomaly to the pregnancy. | The American journal of gastroenterology 20010101 |
[Guidelines of the DGVS. Chronic active course. German Society of Digestive and Metabolic Diseases]. | Zeitschrift fur Gastroenterologie 20010101 |
Therapeutic drug monitoring of azathioprine and 6-mercaptopurine metabolites in Crohn disease. | Scandinavian journal of gastroenterology 20010101 |
6-mercaptopurine dosage and pharmacokinetics influence the degree of bone marrow toxicity following high-dose methotrexate in children with acute lymphoblastic leukemia. | Leukemia 20010101 |
Severe life-threatening diarrhea caused by azathioprine but not by 6-mercaptopurine. | Digestion 20010101 |
Prognostic value of day 14 blast percentage and the absolute blast index in bone marrow of children with acute lymphoblastic leukemia. | Pediatric hematology and oncology 20010101 |
Intrathecal chemotherapy with antineoplastic agents in children. | Paediatric drugs 20010101 |
Cyclosporine in ulcerative colitis: state of the art. | Acta gastro-enterologica Belgica 20010101 |
[Treatment of acute lymphoblastic leukemia in adults as an unsolved problem]. | Terapevticheskii arkhiv 20010101 |
[Experimental study of radiosensitizing effect of analogs of purines and pyrimidine bases in cultured HeLa cells]. | Vestnik Rossiiskoi akademii meditsinskikh nauk 20010101 |
Pharmacokinetic considerations in the treatment of inflammatory bowel disease. | Clinical pharmacokinetics 20010101 |
Pharmacogenetics: the therapeutic drug monitoring of the future? | Clinical pharmacokinetics 20010101 |
Favorable outcome for children and adolescents with T-cell lymphoblastic lymphoma with an intensive ALL-type therapy without local radiotherapy. | Annals of hematology 20010101 |
Late effects of anticancer therapy on kidney function in children with acute lymphoblastic leukemia. | Bratislavske lekarske listy 20010101 |
Recent advances in the pharmacogenomics of thiopurine methyltransferase. | The pharmacogenomics journal 20010101 |
Dosing time-dependent pharmacological effects of anti-metabolites for rat cardiac graft. | Research communications in molecular pathology and pharmacology 20010101 |
Immune hemolytic anemia induced by 6-mercaptopurine. | Transfusion 20000101 |
Cognitive sequelae in children treated for acute lymphoblastic leukemia with dexamethasone or prednisone. | Journal of pediatric hematology/oncology 20000101 |
Veno-occlusive disease of the liver associated with thiopurines in a child with acute lymphoblastic leukemia. | Pediatric hematology and oncology 20000101 |
Assessment of brain perfusion by 99mTc-HMPAO SPECT in akinetic mutism due to high-dose intravenous methotrexate therapy. | Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 19971001 |
Piperacillin-induced seizures. | Clinical pediatrics 19970801 |
Thiopurine methyltransferase activity in the erythrocytes of adults and children: and HPLC-linked assay. | Clinica chimica acta; international journal of clinical chemistry 19970318 |
6-Mercaptopurine decreases the Bcl-2/Bax ratio and induces apoptosis in activated splenic B lymphocytes. | Molecular pharmacology 19970301 |
Myelodysplastic syndrome following successful therapy of acute promyelocytic leukemia. | Leukemia 19970101 |
The successful treatment of autoimmune hepatitis with 6-mercaptopurine after failure with azathioprine. | Gastroenterology 19960101 |
Inhibition of human thiopurine methyltransferase by furosemide, bendroflumethiazide and trichlormethiazide. | European journal of clinical pharmacology 19960101 |
HPLC analysis of azathioprine metabolites in red blood cells, plasma and urine in renal transplant recipients. | International journal of clinical pharmacology and therapeutics 19951201 |
Structure-activity relationships for the binding of ligands to xanthine or guanine phosphoribosyl-transferase from Toxoplasma gondii. | Biochemical pharmacology 19951109 |
Low-dose 6-mercaptopurine in inflammatory bowel disease is associated with minimal hematologic toxicity. | Digestive diseases and sciences 19940801 |
Behavioral effects of corticosteroids in children with acute lymphoblastic leukemia. | Medical and pediatric oncology 19920101 |
Hepatocellular carcinoma and bladder cancer as complications following five years of chemotherapy for acute myeloblastic leukemia. | Japanese journal of medicine 19900101 |
An adult case of acute lymphoblastic leukemia with necrotizing leukoencephalopathy. | Japanese journal of medicine 19900101 |
Protection against isoproterenol-induced myocardial necrosis in rats by 6-mercaptopurine and 6-thioguanine or by irradiation. | Research communications in chemical pathology and pharmacology 19890301 |
Aggressive treatment improves survival in adult acute lymphoblastic leukemia. | European journal of haematology 19881101 |
[Acute pericarditis caused by daunorubicin in acute myelocytic leukemia]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 19880601 |
Severe vincristine neurotoxicity in a patient with Charcot-Marie-Tooth disease. | Pediatric hematology and oncology 19880101 |
Hepatocellular carcinoma in a long-term survivor of acute lymphocytic leukemia. | Cancer 19871115 |
[Daunomycin-induced cardiogenic shock in a case of acute myelogenous leukemia]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 19870901 |
Superior sagittal sinus thrombosis associated with Evans' syndrome of haemolytic anaemia. | Journal of neurology 19850101 |
[Porphyria cutanea tarda caused by methotrexate and buthiopurine therapy]. | Zeitschrift fur Hautkrankheiten 19830215 |
Antiviral effects if ribavirin and 6-mercapto-9-tetrahydro-2-furylpurine against dengue viruses in vitro. | Antiviral research 19820501 |
Muscular degeneration in rats after postnatal treatment with 6-mercaptopurine. | Drug and chemical toxicology 19810101 |
Hypersensitivity and jaundice due to azathioprine. | Postgraduate medical journal 19800401 |
[Hemolysis after combined azathioprine and allopurinol therapy]. | Acta medica Austriaca 19790101 |
Encephalomyelopathy following intrathecal methotrexate treatment in a child with acute leukemia. | Cancer 19780901 |
Neuraxonal dystrophy of the brain in patients receiving antineoplastic chemotherapy. | Acta neuropathologica 19770331 |
Cytogenetic studies in a patient with acute granulocytic leukemia of seven and one-half years duration. | Blood 19751101 |
[Carcinoma of the liver in a child after seven-year complete remission of acute lymphoblastic leukaemia(author's transl)]. | Deutsche medizinische Wochenschrift (1946) 19750905 |
Immunosuppressive and cytotoxic chemotherapy: long-term complications. | Annals of internal medicine 19750101 |
Combination therapy in 130 patients with acute lymphoblastic leukemia (protocol 06 LA 66-Paris). | Cancer research 19731201 |
Seizures associated with vincristine sulfate therapy. | The Journal of pediatrics 19730401 |
Anemias with renal transplantation. | JAMA 19720911 |
Hematuria and crystalluria after high-dose 6-mercaptopurine administration. | The New England journal of medicine 19720810 |
Daunorubicin. Results in childhood leukaemia. | Archives of disease in childhood 19720401 |
6-Azauridine in combination chemotherapy of childhood acute myelocytic leukemia. | Cancer 19720401 |
Clinical note: allergic reaction to daunomycin (NSC-82151). | Cancer chemotherapy reports 19701201 |
Development of myeloblastoma with massive breast and ovarian involvement during remission in acute leukemia. | Cancer 19691001 |
Purine analogs as potential anticytomegalovirus agents. | Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 19690901 |
Vincristine-induced neuropathy. A clinical study of fifty leukemic patients. | Neurology 19690401 |
Neurofibrillary degeneration induced by vincristine therapy. | Archives of neurology 19690201 |
Neuropathy in lymphoblastic leukemia treated with vincristine. | Archives of neurology 19670401 |
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