CAS 480-40-0 | 5,7-Dihydroxyflavone | CAS Number 480-40-0

Title	Journal
Quercetin and chrysin inhibit nickel-induced invasion and migration by downregulation of TLR4/NF-κB signaling in A549 cells.	Chemico-biological interactions 20180825
Chrysin, a natural and biologically active flavonoid suppresses tumor growth of mouse B16F10 melanoma cells: In vitro and In vivo study.	Chemico-biological interactions 20180301
Protective role of chrysin on 6-hydroxydopamine-induced neurodegeneration a mouse model of Parkinson's disease: Involvement of neuroinflammation and neurotrophins.	Chemico-biological interactions 20180105
Incorporation of metabolic enzymes to improve predictivity of reporter gene assay results for estrogenic and anti-androgenic activity.	Reproductive toxicology (Elmsford, N.Y.) 20180101
Chrysin attenuates testosterone-induced benign prostate hyperplasia in rats.	Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20180101
Restorative effects of Chrysin pretreatment on oxidant-antioxidant status, inflammatory cytokine production, and apoptotic and autophagic markers in acute paracetamol-induced hepatotoxicity in rats: An experimental and biochemical study.	Journal of biochemical and molecular toxicology 20171101
Chrysin and silibinin sensitize human glioblastoma cells for arsenic trioxide.	Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20170701
Chrysin, a PPAR-γ agonist improves myocardial injury in diabetic rats through inhibiting AGE-RAGE mediated oxidative stress and inflammation.	Chemico-biological interactions 20160425
3-Methyl-4,5-dihydro-oxepine, polyoxygenated seco-cyclohexenes and cyclohexenes from Uvaria flexuosa and their anti-inflammatory activity.	Phytochemistry 20160201
Flavonoids suppress human glioblastoma cell growth by inhibiting cell metabolism, migration, and by regulating extracellular matrix proteins and metalloproteinases expression.	Chemico-biological interactions 20151205
Chrysin attenuates liver fibrosis and hepatic stellate cell activation through TGF-β/Smad signaling pathway.	Chemico-biological interactions 20151005
Combination of chrysin and cisplatin promotes the apoptosis of Hep G2 cells by up-regulating p53.	Chemico-biological interactions 20150505
Chrysin, baicalein and galangin are indirect activators of the human constitutive androstane receptor (CAR).	Toxicology letters 20150304
Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and α-fetoprotein.	Toxicological sciences : an official journal of the Society of Toxicology 20150201
Investigation of the effects of some phenolic compounds on the activities of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase from human erythrocytes.	Journal of biochemical and molecular toxicology 20141101
Chrysin alleviates testicular dysfunction in adjuvant arthritic rats via suppression of inflammation and apoptosis: comparison with celecoxib.	Toxicology and applied pharmacology 20140901
Dietary flavonoids fisetin and myricetin: dual inhibitors of Plasmodium falciparum falcipain-2 and plasmepsin II.	Fitoterapia 20140401
7,8-Dihydroxyflavone, a TrkB agonist, attenuates behavioral abnormalities and neurotoxicity in mice after administration of methamphetamine.	Psychopharmacology 20140101
Chrysin inhibits metastatic potential of human triple-negative breast cancer cells by modulating matrix metalloproteinase-10, epithelial to mesenchymal transition, and PI3K/Akt signaling pathway.	Journal of applied toxicology : JAT 20140101
Chrysin and luteolin alleviate vascular complications associated with insulin resistance mainly through PPAR-γ activation.	The American journal of Chinese medicine 20140101
Quantitative high-throughput profiling of environmental chemicals and drugs that modulate farnesoid X receptor.	Scientific reports 20140101
The O-methylation of chrysin markedly improves its intestinal anti-inflammatory properties: Structure-activity relationships of flavones.	Biochemical pharmacology 20131215
Chrysin enhances sensitivity of BEL-7402/ADM cells to doxorubicin by suppressing PI3K/Akt/Nrf2 and ERK/Nrf2 pathway.	Chemico-biological interactions 20131025
Pyranoflavones: a group of small-molecule probes for exploring the active site cavities of cytochrome P450 enzymes 1A1, 1A2, and 1B1.	Journal of medicinal chemistry 20130523
Chrysin suppresses renal carcinogenesis via amelioration of hyperproliferation, oxidative stress and inflammation: plausible role of NF-κB.	Toxicology letters 20130204
Protection by chrysin, apigenin, and luteolin against oxidative stress is mediated by the Nrf2-dependent up-regulation of heme oxygenase 1 and glutamate cysteine ligase in rat primary hepatocytes.	Archives of toxicology 20130101
Rat α-Fetoprotein binding affinities of a large set of structurally diverse chemicals elucidated the relationships between structures and binding affinities.	Chemical research in toxicology 20121119
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.	Bioorganic & medicinal chemistry 20121115
Ameliorating effects of quercetin and chrysin on 2,3,7,8-tetrachlorodibenzo- p-dioxin-induced nephrotoxicity in rats.	Toxicology and industrial health 20121101
Simultaneous determination of baicalin, wogonoside, baicalein, wogonin, oroxylin A and chrysin of Radix scutellariae extract in rat plasma by liquid chromatography tandem mass spectrometry.	Journal of pharmaceutical and biomedical analysis 20121101
Drug screening study using glioma stem-like cells.	Molecular medicine reports 20121101
Induction of apoptosis by 7-piperazinethylchrysin in HCT-116 human colon cancer cells.	Oncology reports 20121101
Targeting tumor ubiquitin-proteasome pathway with polyphenols for chemosensitization.	Anti-cancer agents in medicinal chemistry 20121001
Protective role of chrysin against oxidative stress in d-galactose-induced aging in an experimental rat model.	Geriatrics & gerontology international 20121001
Evaluation of the structure-activity relationship of flavonoids as antioxidants and toxicants of zebrafish larvae.	Food chemistry 20120915
A flavonoid component from Docynia delavayi (Franch.) Schneid represses transplanted H22 hepatoma growth and exhibits low toxic effect on tumor-bearing mice.	Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120901
Simultaneous determination of active flavonoids and alkaloids of Tang-Min-Ling-Pill in rat plasma by liquid chromatography tandem mass spectrometry.	Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120901
AMP-activated protein kinase (AMPK) activation is involved in chrysin-induced growth inhibition and apoptosis in cultured A549 lung cancer cells.	Biochemical and biophysical research communications 20120706
Phytochemical and antimicrobial investigations of stilbenoids and flavonoids isolated from three species of Combretaceae.	Fitoterapia 20120701
Chrysin attenuates allergic airway inflammation by modulating the transcription factors T-bet and GATA-3 in mice.	Molecular medicine reports 20120701
Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13.	Bioorganic & medicinal chemistry letters 20120615
Beneficial effects of chrysin on the reproductive system of adult male rats.	Andrologia 20120601
Chrysin restores PDGF-induced inhibition on protein tyrosine phosphatase and reduces PDGF signaling in cultured VSMCs.	The Journal of nutritional biochemistry 20120601
Discovery of flavonoid derivatives as anti-HCV agents via pharmacophore search combining molecular docking strategy.	European journal of medicinal chemistry 20120601
Nephroprotective efficacy of chrysin against cisplatin-induced toxicity via attenuation of oxidative stress.	The Journal of pharmacy and pharmacology 20120601
Inhibitory effects of dietary flavonoids on purified hepatic NADH-cytochrome b5 reductase: structure-activity relationships.	Chemico-biological interactions 20120530
Differential effects of flavonoids on barrier integrity in human intestinal Caco-2 cells.	Journal of agricultural and food chemistry 20120509
Mutagenicity of flavonoids assayed by bacterial reverse mutation (Ames) test.	Molecules (Basel, Switzerland) 20120507
Characterization of phenolic compounds in flowers of wild medicinal plants from Northeastern Portugal.	Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120501
Optimized assays for human UDP-glucuronosyltransferase (UGT) activities: altered alamethicin concentration and utility to screen for UGT inhibitors.	Drug metabolism and disposition: the biological fate of chemicals 20120501
Flavones and structurally related 4-chromenones inhibit carbonic anhydrases by a different mechanism of action compared to coumarins.	Bioorganic & medicinal chemistry letters 20120501
Inhibitory effects of acetylmelodorinol, chrysin and polycarpol from Mitrella kentii on prostaglandin E₂ and Thromboxane B₂ production and platelet activating factor receptor binding.	Molecules (Basel, Switzerland) 20120426
The anticancer activity of propolis.	Folia histochemica et cytobiologica 20120424
Development of a new class of aromatase inhibitors: design, synthesis and inhibitory activity of 3-phenylchroman-4-one (isoflavanone) derivatives.	Bioorganic & medicinal chemistry 20120415
Chrysin improves cognitive deficits and brain damage induced by chronic cerebral hypoperfusion in rats.	European journal of pharmacology 20120405
Methylated chrysin reduced cell proliferation, but antagonized cytotoxicity of other anticancer drugs in acute lymphoblastic leukemia.	Anti-cancer drugs 20120401
Glycosylation of various flavonoids by recombinant oleandomycin glycosyltransferase from Streptomyces antibioticus in batch and repeated batch modes.	Biotechnology letters 20120301
Bioassay-guided isolation of vasorelaxant compounds from Ziziphora clinopodioides Lam. (Lamiaceae).	Fitoterapia 20120301
Regulation of NF-κB activity in astrocytes: effects of flavonoids at dietary-relevant concentrations.	Biochemical and biophysical research communications 20120217
Molecular structure and vibrational spectroscopic studies of Chrysin using HF and Density Functional Theory.	Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120215
Chrysin protects against cisplatin-induced colon. toxicity via amelioration of oxidative stress and apoptosis: probable role of p38MAPK and p53.	Toxicology and applied pharmacology 20120201
Molecular dynamic behavior and binding affinity of flavonoid analogues to the cyclin dependent kinase 6/cyclin D complex.	Journal of chemical information and modeling 20120123
Induction of oxidative DNA damage by flavonoids of propolis: its mechanism and implication about antioxidant capacity.	Chemical research in toxicology 20120113
Dual protective effect of Passiflora incarnata in epilepsy and associated post-ictal depression.	Journal of ethnopharmacology 20120106
Wogonin and related natural flavones overcome tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein resistance of tumors by down-regulation of c-FLIP protein and up-regulation of TRAIL receptor 2 expression.	The Journal of biological chemistry 20120102
Ethanolic extract of fructus Alpinia oxyphylla protects against 6-hydroxydopamine-induced damage of PC12 cells in vitro and dopaminergic neurons in zebrafish.	Cellular and molecular neurobiology 20120101
¹H-NMR simultaneous identification of health-relevant compounds in propolis extracts.	Phytochemical analysis : PCA 20120101
Chrysin enhances doxorubicin-induced cytotoxicity in human lung epithelial cancer cell lines: the role of glutathione.	Toxicology and applied pharmacology 20120101
Greco-arab and islamic herbal-derived anticancer modalities: from tradition to molecular mechanisms.	Evidence-based complementary and alternative medicine : eCAM 20120101
Luteolin Suppresses Inflammatory Mediator Expression by Blocking the Akt/NFκB Pathway in Acute Lung Injury Induced by Lipopolysaccharide in Mice.	Evidence-based complementary and alternative medicine : eCAM 20120101
A searchable cross-platform gene expression database reveals connections between drug treatments and disease.	BMC genomics 20120101
Effect of an Ethanol Extract of Scutellaria baicalensis on Relaxation in Corpus Cavernosum Smooth Muscle.	Evidence-based complementary and alternative medicine : eCAM 20120101
Molecular modeling study of chiral separation and recognition mechanism of β-adrenergic antagonists by capillary electrophoresis.	International journal of molecular sciences 20120101
A naturally occurring carotenoid, lutein, reduces PDGF and H₂O₂ signaling and compromised migration in cultured vascular smooth muscle cells.	Journal of biomedical science 20120101
Acute exposure of apigenin induces hepatotoxicity in Swiss mice.	PloS one 20120101
Role of transcription factors in peripheral nerve regeneration.	Frontiers in molecular neuroscience 20120101
Bufalin induces lung cancer cell apoptosis via the inhibition of PI3K/Akt pathway.	International journal of molecular sciences 20120101
AHR and the Transcriptional Regulation of Type-17/22 ILC.	Frontiers in immunology 20120101
Inhibitory effects and underlying mechanism of 7-hydroxyflavone phosphate ester in HeLa cells.	PloS one 20120101
Enzymatic modification of chitosan with quercetin and its application as antioxidant edible films.	Prikladnaia biokhimiia i mikrobiologiia 20120101
Plant HDAC inhibitor chrysin arrest cell growth and induce p21WAF1 by altering chromatin of STAT response element in A375 cells.	BMC cancer 20120101
Microbial transformations of 7-hydroxyflavanone.	TheScientificWorldJournal 20120101
Analgesic and Anti-Inflammatory Activities of Methanol Extract of Ficus pumila L. in Mice.	Evidence-based complementary and alternative medicine : eCAM 20120101
Limitations of inhibitory activities of polyphenols on furin-mediated substrate processing.	Current medicinal chemistry 20120101
A novel relationship between the radical-scavenging activity of flavonoids and enthalpy of formation revealed with Hartree-Fock computations and thermochemical deduction.	Redox report : communications in free radical research 20120101
Chrysin, a natural and biologically active flavonoid, influences a murine leukemia model in vivo through enhancing populations of T-and B-cells, and promoting macrophage phagocytosis and NK cell cytotoxicity.	In vivo (Athens, Greece) 20120101
Evaluation of the mutagenic activity of chrysin, a flavonoid inhibitor of the aromatization process.	Journal of toxicology and environmental health. Part A 20120101
Chemical compositions and antioxidant activities of water extracts of Chinese propolis.	Journal of agricultural and food chemistry 20111214
Chrysin protects mice from Staphylococcus aureus pneumonia.	Journal of applied microbiology 20111201
New synthetic anti-inflammatory chrysin analog, 5,7-dihydroxy-8-(pyridine-4yl)flavone.	European journal of pharmacology 20111130
Fast chromatographic separation for the quantitation of the main flavone dyes in Reseda luteola (weld).	Journal of chromatography. A 20111125
The anticancer flavonoid chrysin induces the unfolded protein response in hepatoma cells.	Journal of cellular and molecular medicine 20111101
Protective effect of chrysin on carbon tetrachloride (CCl4)-induced tissue injury in male Wistar rats.	Toxicology and industrial health 20111101
Hybrid flavan-chalcones, aromatase and lipoxygenase inhibitors, from Desmos cochinchinensis.	Phytochemistry 20111101
Investigations on membrane perturbation by chrysin and its copper complex using self-assembled lipid bilayers.	Langmuir : the ACS journal of surfaces and colloids 20111101
Ultra high performance liquid chromatography-time of flight mass spectrometry for analysis of avocado fruit metabolites: method evaluation and applicability to the analysis of ripening degrees.	Journal of chromatography. A 20111021
Potency of inhibition of human DNA topoisomerase I by flavones assessed through physicochemical parameters.	Free radical biology & medicine 20111001
Flavonoids in Scutellaria immaculata and S. ramosissima (Lamiaceae) and their biological activity.	The Journal of pharmacy and pharmacology 20111001
Protective effects of quercetin and chrysin against 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induced oxidative stress, body wasting and altered cytokine productions in rats.	Immunopharmacology and immunotoxicology 20110901
Antiproliferative effect of chrysin on anaplastic thyroid cancer.	The Journal of surgical research 20110901
A chrysin analog exhibited strong inhibitory activities against both PGE2 and NO production.	European journal of medicinal chemistry 20110901
Docking and 3D-QSAR (quantitative structure activity relationship) studies of flavones, the potent inhibitors of p-glycoprotein targeting the nucleotide binding domain.	European journal of medicinal chemistry 20110901
Potentiation of arsenic trioxide-induced apoptosis by 8-bromo-7-methoxychrysin in human leukemia cells involves depletion of intracellular reduced glutathione.	Acta biochimica et biophysica Sinica 20110901
Methylated chrysin induces co-ordinated attenuation of the canonical Wnt and NF-kB signaling pathway and upregulates apoptotic gene expression in the early hepatocarcinogenesis rat model.	Chemico-biological interactions 20110815
Chrysin protects epidermal keratinocytes from UVA- and UVB-induced damage.	Journal of agricultural and food chemistry 20110810
Inhibition of melanogenesis by 5,7-dihydroxyflavone (chrysin) via blocking adenylyl cyclase activity.	Biochemical and biophysical research communications 20110722
Chrysin suppresses mast cell-mediated allergic inflammation: involvement of calcium, caspase-1 and nuclear factor-κB.	Toxicology and applied pharmacology 20110701
Wogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis in cancer cells by transcriptional suppression of Mcl-1.	Cell death & disease 20110701
Resveratrol in combination with other dietary polyphenols concomitantly enhances antiproliferation and UGT1A1 induction in Caco-2 cells.	Life sciences 20110606
Chemical composition of the ethanolic propolis extracts and its effect on HeLa cells.	Journal of ethnopharmacology 20110601
Chrysin reduces proliferation and induces apoptosis in the human prostate cancer cell line pc-3.	Clinics (Sao Paulo, Brazil) 20110601
Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids.	Bioorganic & medicinal chemistry 20110501
Intrinsic and extrinsic regulation of innate immune receptors.	Yonsei medical journal 20110501
Anti-asthmatic potential of chrysin on ovalbumin-induced bronchoalveolar hyperresponsiveness in rats.	Pharmaceutical biology 20110501
Quercetin-iron chelates are transported via glucose transporters.	Free radical biology & medicine 20110415
Screening of bacterial cytochrome P450s responsible for regiospecific hydroxylation of (iso)flavonoids.	Enzyme and microbial technology 20110407
Chrysin promotes tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induced apoptosis in human cancer cell lines.	Toxicology in vitro : an international journal published in association with BIBRA 20110401
Can flavonoids from honey alter multidrug resistance?	Medical hypotheses 20110401
Structure-activity relationships of flavonoids as inhibitors of breast cancer resistance protein (BCRP).	Bioorganic & medicinal chemistry 20110315
Ultrasonic-assisted synthesis of chrysin derivatives linked with 1,2,3-triazoles by 1,3-dipolar cycloaddition reaction.	Ultrasonics sonochemistry 20110301
Chrysin abrogates early hepatocarcinogenesis and induces apoptosis in N-nitrosodiethylamine-induced preneoplastic nodules in rats.	Toxicology and applied pharmacology 20110215
Furoxan nitric oxide donor coupled chrysin derivatives: synthesis and vasculoprotection.	Bioorganic & medicinal chemistry letters 20110215
Chrysin-induced apoptosis is mediated through p38 and Bax activation in B16-F1 and A375 melanoma cells.	International journal of oncology 20110201
Chemopreventive effect of dietary polyphenols in colorectal cancer cell lines.	Nutrition research (New York, N.Y.) 20110201
Anticonvulsant and neurotoxicity profile of the rhizome of Smilax china Linn. in mice.	Indian journal of pharmacology 20110201
Ethanolic Extract of Propolis Augments TRAIL-Induced Apoptotic Death in Prostate Cancer Cells.	Evidence-based complementary and alternative medicine : eCAM 20110101
Effects of methimazole on the elimination of irinotecan.	Cancer chemotherapy and pharmacology 20110101
Ethanol extract of chinese propolis facilitates functional recovery of locomotor activity after spinal cord injury.	Evidence-based complementary and alternative medicine : eCAM 20110101
Suppressive Effect on Lipopolysaccharide-Induced Proinflammatory Mediators by Citrus aurantium L. in Macrophage RAW 264.7 Cells via NF-κB Signal Pathway.	Evidence-based complementary and alternative medicine : eCAM 20110101
Methylated chrysin, a dimethoxy flavone, partially suppresses the development of liver preneoplastic lesions induced by N-nitrosodiethylamine in rats.	Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110101
Concentration-Dependent Protection by Ethanol Extract of Propolis against γ-Ray-Induced Chromosome Damage in Human Blood Lymphocytes.	Evidence-based complementary and alternative medicine : eCAM 20110101
Inhibitory effect of chinese propolis on phosphatidylcholine-specific phospholipase C activity in vascular endothelial cells.	Evidence-based complementary and alternative medicine : eCAM 20110101
Apigenin inhibits tumor necrosis factor alpha plus high glucose-induced LOX-1 expression in human endothelial cells.	Microvascular research 20110101
Synthesis, biological evaluation of chrysin derivatives as potential immunosuppressive agents.	European journal of medicinal chemistry 20110101
In vitro studies on the inhibition of colon cancer by butyrate and polyphenolic compounds.	Nutrition and cancer 20110101
The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease.	International journal of molecular sciences 20110101
Facile synthesis of chrysin-derivatives with promising activities as aromatase inhibitors.	Natural product communications 20110101
Honey induces apoptosis in renal cell carcinoma.	Pharmacognosy magazine 20110101
Chrysin modulates ethanol metabolism in Wistar rats: a promising role against organ toxicities.	Alcohol and alcoholism (Oxford, Oxfordshire) 20110101
Novel natural inhibitors of CYP1A2 identified by in silico and in vitro screening.	International journal of molecular sciences 20110101
Efficacy of Brazilian Propolis against Herpes Simplex Virus Type 1 Infection in Mice and Their Modes of Antiherpetic Efficacies.	Evidence-based complementary and alternative medicine : eCAM 20110101
Elevated BCRP/ABCG2 expression confers acquired resistance to gefitinib in wild-type EGFR-expressing cells.	PloS one 20110101
Evaluation of antiaggregatory activity of flavonoid aglycone series.	Nutrition journal 20110101
Polyphenolic fraction of Algerian propolis protects rat kidney against acute oxidative stress induced by doxorubicin.	Indian journal of nephrology 20110101
Research strategies in the study of the pro-oxidant nature of polyphenol nutraceuticals.	Journal of toxicology 20110101
An integrated bioinformatics approach identifies elevated cyclin E2 expression and E2F activity as distinct features of tamoxifen resistant breast tumors.	PloS one 20110101
Development and validation of a UHPLC method for the determination of flavonoids in red wine.	Journal of AOAC International 20110101
5-allyl-7-gen-difluoromethoxychrysin enhances TRAIL-induced apoptosis in human lung carcinoma A549 cells.	BMC cancer 20110101
Teucrium plant species as natural sources of novel anticancer compounds: antiproliferative, proapoptotic and antioxidant properties.	International journal of molecular sciences 20110101
Structure of flavonoids influences the degree inhibition of Benzo(a)pyrene - induced DNA damage and micronuclei in HepG2 cells.	Neoplasma 20110101
Selection of herbal therapeutics against deltatoxin mediated Clostridial infections.	Bioinformation 20110101
Dietary α-eleostearic acid ameliorates experimental inflammatory bowel disease in mice by activating peroxisome proliferator-activated receptor-γ.	PloS one 20110101
Honey and renal cell carcinoma.	Pharmacognosy magazine 20110101
Antioxidant and potential anti-inflammatory activity of extracts and formulations of white tea, rose, and witch hazel on primary human dermal fibroblast cells.	Journal of inflammation (London, England) 20110101
Drug discovery for Duchenne muscular dystrophy via utrophin promoter activation screening.	PloS one 20110101
Pro-inflammatory gene expression and neurotoxic effects of activated microglia are attenuated by absence of CCAAT/enhancer binding protein β.	Journal of neuroinflammation 20110101
Antimutagenic and free radical scavenger effects of leaf extracts from Accacia salicina.	Annals of clinical microbiology and antimicrobials 20110101
Protective effect of aqueous extract of Oroxylum indicum Linn. (root bark) against DNBS-induced colitis in rats.	Indian journal of pharmacology 20110101
Inhibitors of alphavirus entry and replication identified with a stable Chikungunya replicon cell line and virus-based assays.	PloS one 20110101
Bioactive constituents and medicinal importance of genus Alnus.	Pharmacognosy reviews 20110101
A Review on the Taxonomy, Ethnobotany, Chemistry and Pharmacology of Oroxylum indicum Vent.	Indian journal of pharmaceutical sciences 20110101
Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives.	Chemical research in toxicology 20101220
Anti-inflammatory effects of dietary phenolic compounds in an in vitro model of inflamed human intestinal epithelium.	Chemico-biological interactions 20101205
Gene expression profiles in human peripheral blood mononuclear cells as biomarkers for nutritional in vitro and in vivo investigations.	Genes & nutrition 20101201
Chrysin suppresses LPS-stimulated proinflammatory responses by blocking NF-κB and JNK activations in microglia cells.	Neuroscience letters 20101126
Flavonoids from Halostachys caspica and their antimicrobial and antioxidant activities.	Molecules (Basel, Switzerland) 20101105
Antifilarial activity in vitro and in vivo of some flavonoids tested against Brugia malayi.	Acta tropica 20101101
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.	Bioorganic & medicinal chemistry letters 20101101
Induction of apoptosis by 5,7-dihydroxy-8-nitrochrysin in breast cancer cells: the role of reactive oxygen species and Akt.	International journal of oncology 20101101
Synthesis and biological evaluation of novel benzyl-substituted flavones as free radical (DPPH) scavengers and α-glucosidase inhibitors.	Journal of Asian natural products research 20101101
Isoform-selective inhibition of chrysin towards human cytochrome P450 1A2. Kinetics analysis, molecular docking, and molecular dynamics simulations.	Bioorganic & medicinal chemistry letters 20101015
Multivariate QSAR study on the antimutagenic activity of flavonoids against 3-NFA on Salmonella typhimurium TA98.	European journal of medicinal chemistry 20101001
Inhibition of CCAAT/enhancer binding protein δ expression by chrysin in microglial cells results in anti-inflammatory and neuroprotective effects.	Journal of neurochemistry 20101001
Acacia honey and chrysin reduce proliferation of melanoma cells through alterations in cell cycle progression.	International journal of oncology 20101001
Separation optimization of quercetin, hesperetin and chrysin in honey by micellar liquid chromatography and experimental design.	Journal of separation science 20101001
Seasonal variation, chemical composition and antioxidant activity of Brazilian propolis samples.	Evidence-based complementary and alternative medicine : eCAM 20100901
Flavonoid combinations cause synergistic inhibition of proinflammatory mediator secretion from lipopolysaccharide-induced RAW 264.7 cells.	Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20100901
Effects of propolis from different areas on mast cell degranulation and identification of the effective components in propolis.	International immunopharmacology 20100901
Prenylflavonoids and prenyl/alkyl-phloroacetophenones: synthesis and antitumour biological evaluation.	European journal of medicinal chemistry 20100901
Selective inhibition of methoxyflavonoids on human CYP1B1 activity.	Bioorganic & medicinal chemistry 20100901
Ellagic acid, phenolic acids, and flavonoids in Malaysian honey extracts demonstrate in vitro anti-inflammatory activity.	Nutrition research (New York, N.Y.) 20100901
Chrysin blocks topotecan-induced apoptosis in Caco-2 cells in spite of inhibition of ABC-transporters.	Biochemical pharmacology 20100815
Role of oxidative stress in the antitumoral action of a new vanadyl(IV) complex with the flavonoid chrysin in two osteoblast cell lines: relationship with the radical scavenger activity.	Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20100801
Cucullamide, a new putrescine bisamide from Amoora cucullata.	Chemical & pharmaceutical bulletin 20100801
An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds.	Journal of natural products 20100723
8-Bromo-7-methoxychrysin-induced apoptosis of hepatocellular carcinoma cells involves ROS and JNK.	World journal of gastroenterology 20100721
Chrysin sensitizes tumor necrosis factor-alpha-induced apoptosis in human tumor cells via suppression of nuclear factor-kappaB.	Cancer letters 20100701
Structure-affinity relationship of flavones on binding to serum albumins: effect of hydroxyl groups on ring A.	Molecular nutrition & food research 20100701
Chrysin suppresses IL-6-induced angiogenesis via down-regulation of JAK1/STAT3 and VEGF: an in vitro and in ovo approach.	Journal of agricultural and food chemistry 20100609
Nitrofurantoin transport by placental choriocarcinoma JAr cells: involvement of BCRP, OATP2B1 and other MDR transporters.	Archives of gynecology and obstetrics 20100601
A comparative study of flavonoid analogues on streptozotocin-nicotinamide induced diabetic rats: quercetin as a potential antidiabetic agent acting via 11beta-hydroxysteroid dehydrogenase type 1 inhibition.	European journal of medicinal chemistry 20100601
Dietary bioflavonoids inhibit Escherichia coli ATP synthase in a differential manner.	International journal of biological macromolecules 20100601
Influence of chrysin on hepatic marker enzymes and lipid profile against D-galactosamine-induced hepatotoxicity rats.	Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100601
Effect of selected flavones on cancer and endothelial cells.	General physiology and biophysics 20100601
Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19).	Bioorganic & medicinal chemistry letters 20100515
Synthesis, characterization and vasculoprotective effects of nitric oxide-donating derivatives of chrysin.	Bioorganic & medicinal chemistry 20100501
Study on the constituents of Mexican propolis and their cytotoxic activity against PANC-1 human pancreatic cancer cells.	Journal of natural products 20100423
Effect of chrysin on hepatoprotective and antioxidant status in D-galactosamine-induced hepatitis in rats.	European journal of pharmacology 20100410
Antigenotoxic studies of different substances to reduce the DNA damage induced by aflatoxin B(1) and ochratoxin A.	Toxins 20100401
Spectrometric study of the interaction between alpinetin and bovine serum albumin using chemometrics approaches.	Analytica chimica acta 20100324
High expression of gabarapl1 is associated with a better outcome for patients with lymph node-positive breast cancer.	British journal of cancer 20100316
Dietary flavonoids activate the constitutive androstane receptor (CAR).	Journal of agricultural and food chemistry 20100224
Flavones suppress type I IL-4 receptor signaling by down-regulating the expression of common gamma chain.	FEBS letters 20100219
Potent inhibitor scaffold against Trypanosoma cruzi trans-sialidase.	Bioorganic & medicinal chemistry 20100215
Apigenin, chrysin, and luteolin selectively inhibit chymotrypsin-like and trypsin-like proteasome catalytic activities in tumor cells.	Planta medica 20100201
Design, synthesis and biological evaluation of chrysin long-chain derivatives as potential anticancer agents.	Bioorganic & medicinal chemistry 20100201
Dietary flavonoids suppress azoxymethane-induced colonic preneoplastic lesions in male C57BL/KsJ-db/db mice.	Chemico-biological interactions 20100127
Antiviral activity and mode of action of propolis extracts and selected compounds.	Phytotherapy research : PTR 20100101
In vitro anti-leukemic activity of the ethno-pharmacological plant Scutellaria orientalis ssp. carica endemic to western Turkey.	Phytomedicine : international journal of phytotherapy and phytopharmacology 20100101
Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.	Bioorganic & medicinal chemistry 20100101
Luteolin triggers global changes in the microglial transcriptome leading to a unique anti-inflammatory and neuroprotective phenotype.	Journal of neuroinflammation 20100101
Protection of burn-induced skin injuries by the flavonoid kaempferol.	BMB reports 20100101
Synthesis and preliminary biological evaluation of chrysin derivatives as potential anticancer drugs.	Medicinal chemistry (Shariqah (United Arab Emirates)) 20100101
Potential effects of chrysin on MDA-MB-231 cells.	International journal of molecular sciences 20100101
Impact of dietary polyphenols on carbohydrate metabolism.	International journal of molecular sciences 20100101
Flavonoids activate pregnane x receptor-mediated CYP3A4 gene expression by inhibiting cyclin-dependent kinases in HepG2 liver carcinoma cells.	BMC biochemistry 20100101
Apoptotic effects of chrysin in human cancer cell lines.	International journal of molecular sciences 20100101
Reversal of multidrug resitance by natural substances from plants.	Current topics in medicinal chemistry 20100101
Differential mechanisms for the inhibition of human cytochrome P450 1A2 by apigenin and genistein.	Journal of biochemical and molecular toxicology 20100101
Structural basis for certain naturally occurring bioflavonoids to function as reducing co-substrates of cyclooxygenase I and II.	PloS one 20100101
Antiproliferative effect of Tualang honey on oral squamous cell carcinoma and osteosarcoma cell lines.	BMC complementary and alternative medicine 20100101
Potent modification of inducible CYP1A1 expression by flavonoids.	Biological & pharmaceutical bulletin 20100101
Medicinal plants used in Northern Peru for reproductive problems and female health.	Journal of ethnobiology and ethnomedicine 20100101
Novel screening method for potential skin-whitening compounds by a luciferase reporter assay.	Bioscience, biotechnology, and biochemistry 20100101
Chungsim-Yeunja-Tang decreases the inflammatory response in peripheral blood mononuclear cells from patients with cerebral infarction through an NF-κB dependent mechanism.	Journal of neuroinflammation 20100101
CYP1A1 and CYP3A4 modulation by dietary flavonoids in human intestinal Caco-2 cells.	Toxicology letters 20091215
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.	Journal of medicinal chemistry 20091210
Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors.	Bioorganic & medicinal chemistry letters 20091201
7-Hydroxy-benzopyran-4-one derivatives: a novel pharmacophore of peroxisome proliferator-activated receptor alpha and -gamma (PPARalpha and gamma) dual agonists.	Journal of medicinal chemistry 20091112
Methylation of dietary flavones increases their metabolic stability and chemopreventive effects.	International journal of molecular sciences 20091101
CYP1-mediated antiproliferative activity of dietary flavonoids in MDA-MB-468 breast cancer cells.	Toxicology 20091029
Synthesis of C(7) modified chrysin derivatives designing to inhibit beta-ketoacyl-acyl carrier protein synthase III (FabH) as antibiotics.	Bioorganic & medicinal chemistry 20090901
Effect of flavonoids on androgen and glucocorticoid receptors based on in vitro reporter gene assay.	Bioorganic & medicinal chemistry letters 20090815
Evaluation of radioprotective effects of propolis and its flavonoid constituents: in vitro study on human white blood cells.	Phytotherapy research : PTR 20090801
Cytotoxicity of flavones and flavonols to a human esophageal squamous cell carcinoma cell line (KYSE-510) by induction of G2/M arrest and apoptosis.	Toxicology in vitro : an international journal published in association with BIBRA 20090801
In vitro kinetic properties of the Thr201Met variant of human aromatase gene CYP19A1: functional responses to substrate and product inhibition and enzyme inhibitors.	The Journal of clinical endocrinology and metabolism 20090801
Inhibitory effects of flavonoids isolated from Fragaria ananassa Duch on IgE-mediated degranulation in rat basophilic leukemia RBL-2H3.	Bioorganic & medicinal chemistry 20090801
[Synthesis of biflavones and their interaction with DNA].	Yao xue xue bao = Acta pharmaceutica Sinica 20090801
Development and validation of a high-performance liquid chromatographic method for determination of pinocembrin in rat plasma: application to pharmacokinetic study.	Journal of pharmaceutical and biomedical analysis 20090712
Antifeedant activity of ethanolic extract from Flourensia oolepis and isolation of pinocembrin as its active principle compound.	Bioresource technology 20090701
Antiinflammatory and antinociceptive activities of gossypin and procumbentin--cyclooxygenase-2 (COX-2) inhibition studies.	Phytotherapy research : PTR 20090601
Breast cancer resistance protein interacts with various compounds in vitro, but plays a minor role in substrate efflux at the blood-brain barrier.	Drug metabolism and disposition: the biological fate of chemicals 20090601
Hepatoprotective effect of chrysin on prooxidant-antioxidant status during ethanol-induced toxicity in female albino rats.	The Journal of pharmacy and pharmacology 20090601
Scuteflorins A and B, dihydropyranocoumarins from Scutellaria lateriflora.	Journal of natural products 20090601
Simultaneous quantification of eight major bioactive phenolic compounds in Chinese propolis by high-performance liquid chromatography.	Natural product communications 20090601
Inhibitory effects of flavonoids on TNF-alpha-induced IL-8 gene expression in HEK 293 cells.	BMB reports 20090531
Correlation between antiangiogenic activity and antioxidant activity of various components from propolis.	Molecular nutrition & food research 20090501
Simultaneous determination of 11 active components in two well-known traditional Chinese medicines by HPLC coupled with diode array detection for quality control.	Journal of pharmaceutical and biomedical analysis 20090501
Chrysin, a natural flavone, improves murine inflammatory bowel diseases.	Biochemical and biophysical research communications 20090417
Suppression of the TRIF-dependent signaling pathway of Toll-like receptors by luteolin.	Biochemical pharmacology 20090415
Main flavonoids, DPPH activity, and metal content allow determination of the geographical origin of propolis from the Province of San Juan (Argentina).	Journal of agricultural and food chemistry 20090408
Cytotoxic constituents of chinese propolis.	Journal of natural products 20090401
Food flavonoid aryl hydrocarbon receptor-mediated agonistic/antagonistic/synergic activities in human and rat reporter gene assays.	Analytica chimica acta 20090401
Comparison of intraperitoneal honey and sodium hyaluronate-carboxymethylcellulose (Seprafilm) for the prevention of postoperative intra-abdominal adhesions.	Clinics (Sao Paulo, Brazil) 20090401
Trihydroxynaphthalene reductase of Curvularia lunata--a target for flavonoid action?	Chemico-biological interactions 20090316
Mechanism of CYP2C9 inhibition by flavones and flavonols.	Drug metabolism and disposition: the biological fate of chemicals 20090301
Antioxidant effects of flavonoid from Croatian Cystus incanus L. rich bee pollen.	Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090301
Quantum-SAR extension of the spectral-SAR algorithm: application to polyphenolic anticancer bioactivity.	International journal of molecular sciences 20090301
5,7-Dimeth-oxy-2-phenyl-4H-chromen-4-one.	Acta crystallographica. Section E, Structure reports online 20090301
6,8-Dibromo-5-hydr-oxy-4-oxo-2-phenyl-4H-chromen-7-yl acetate.	Acta crystallographica. Section E, Structure reports online 20090301
2-Bromo-5,7-dimeth-oxy-4-phenyl-quinoline.	Acta crystallographica. Section E, Structure reports online 20090301
Synthesis and promotion angiogenesis effect of chrysin derivatives coupled to NO donors.	Bioorganic & medicinal chemistry letters 20090215
Multiple compounds determination and fingerprint analysis of Lidanpaishi tablet and keli by high-performance liquid chromatography.	Analytica chimica acta 20090202
MS/MS spectral tag-based annotation of non-targeted profile of plant secondary metabolites.	The Plant journal : for cell and molecular biology 20090201
Dimethyl 2,2'-[(4-oxo-2-phenyl-4H-chromene-5,7-diyl)dioxy]diacetate: a more densely packed polymorph.	Acta crystallographica. Section E, Structure reports online 20090201
Discovery of a potent and selective inhibitor for human carbonyl reductase 1 from propionate scanning applied to the macrolide zearalenone.	Bioorganic & medicinal chemistry 20090115
In vitro antitumor mechanisms of various Scutellaria extracts and constituent flavonoids.	Planta medica 20090101
Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases.	BMC medical genomics 20090101
Bear bile: dilemma of traditional medicinal use and animal protection.	Journal of ethnobiology and ethnomedicine 20090101
Structure-activity relationship of 7 flavonoids on recombinant human protein kinase CK2 holoenzyme.	Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20090101
Simple and reliable methods for the determination of sixteen marker components for quality control of Daochi pill by HPLC coupled with diode array detection.	Phytochemical analysis : PCA 20090101
From functional food to medicinal product: systematic approach in analysis of polyphenolics from propolis and wine.	Nutrition journal 20090101
Antiproliferative effects of honey and of its polyphenols: a review.	Journal of biomedicine & biotechnology 20090101
Differential effects of chrysin on nitrofurantoin pharmacokinetics mediated by intestinal breast cancer resistance protein in rats and mice.	Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20090101
Synthesis, cytotoxic activity, and DNA binding properties of copper (II) complexes with hesperetin, naringenin, and apigenin.	Bioinorganic chemistry and applications 20090101
Bee products prevent VEGF-induced angiogenesis in human umbilical vein endothelial cells.	BMC complementary and alternative medicine 20090101
Cofactor-activated phosphorylation is required for inhibition of cortical neuron differentiation by Groucho/TLE1.	PloS one 20090101
Prevention of selenite-induced cataractogenesis by rutin in Wistar rats.	Molecular vision 20090101
[Comparative effects of flavonoids on cell cycle passage and apoptosis induction in human acute lymphoblastic leukemia MT-4 cells].	Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20090101
2-Phenyl-5,7-bis-(prop-2-en-1-yl-oxy)-4H-chromen-4-one.	Acta crystallographica. Section E, Structure reports online 20090101
Analysis of flavonoids in propolis and Ginkgo biloba by micellar electrokinetic capillary chromatography.	Journal of agricultural and food chemistry 20081224
Flow-injection chemiluminescence determination of chrysin and baicalein assisted by theoretical prediction of chemiluminescence behavior of chrysin and baicalein.	Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081201
Antioxidant and antimicrobial effects of phenolic compounds extracts of Northeast Portugal honey.	Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081201
Negative ion 'chip-based' nanospray tandem mass spectrometry for the analysis of flavonoids in glandular trichomes of Lychnophora ericoides Mart. (Asteraceae).	Rapid communications in mass spectrometry : RCM 20081201
[Cytotoxicity of polyphenolic/flavonoid compounds in a leukaemia cell culture].	Arhiv za higijenu rada i toksikologiju 20081201
Authors' correction: chrysin is a Passiflora coerulea extract.	AANA journal 20081201
Hexaaqua-(5,7-dihydr-oxy-4-oxo-2-phenyl-4H-chromene-8-sulfonato)calcium(II) 5,7-dihydr-oxy-4-oxo-2-phenyl-4H-chromene-8-sulfonate trihydrate.	Acta crystallographica. Section E, Structure reports online 20081201
5,7-Bis(benz-yloxy)-2-phenyl-4H-chromen-4-one.	Acta crystallographica. Section E, Structure reports online 20081201
Structural requirements for the flavonoid fisetin in inhibiting fibril formation of amyloid beta protein.	Neuroscience letters 20081031
Protective effects of Chinese propolis and its component, chrysin, against neuronal cell death via inhibition of mitochondrial apoptosis pathway in SH-SY5Y cells.	Journal of agricultural and food chemistry 20081008
Testosterone and dihydrotestosterone inhibit gallbladder motility through multiple signalling pathways.	Steroids 20081001
Relationship between the methylation status of dietary flavonoids and their growth-inhibitory and apoptosis-inducing activities in human cancer cells.	Journal of cellular biochemistry 20081001
Modulation of signalling nuclear factor-kappaB activation pathway by polyphenols in human intestinal Caco-2 cells.	The British journal of nutrition 20080901
A p38-p65 transcription complex induced by endothelin-1 mediates signal transduction in cancer cells.	Biochimica et biophysica acta 20080901
Enhanced detection and structural characterization of flavonoids by complexation with N,O-bis(trimethysilyl)trifluoroacetamide using electrospray ionization mass spectrometry.	Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20080901
Chemical composition and botanical origin of red propolis, a new type of brazilian propolis.	Evidence-based complementary and alternative medicine : eCAM 20080901
[Studies on ethyl acetate soluble constituents of Huanglian Jiedutang].	Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080901
Effect of flavonoids on rat splenocytes, a structure-activity relationship study.	Biochemical pharmacology 20080815
QSAR modeling of the interaction of flavonoids with GABA(A) receptor.	European journal of medicinal chemistry 20080801
Modulation of glucose uptake in a human choriocarcinoma cell line (BeWo) by dietary bioactive compounds and drugs of abuse.	Journal of biochemistry 20080801
Chrysin induces hyperalgesia via the GABAA receptor in mice.	Planta medica 20080801
Protein engineering on biphenyl dioxygenase for conferring activity to convert 7-hydroxyflavone and 5,7-dihydroxyflavone (chrysin).	Journal of bioscience and bioengineering 20080801
Discovery of nonsteroidal 17beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries.	Journal of medicinal chemistry 20080724
Galangin increases the cytotoxic activity of imatinib mesylate in imatinib-sensitive and imatinib-resistant Bcr-Abl expressing leukemia cells.	Cancer letters 20080708
Multi-substrate flavonol O-glucosyltransferases from strawberry (Fragaria x ananassa) achene and receptacle.	Journal of experimental botany 20080701
[Linear scale-up of the separation of active components from Oroxylum indicum using high-speed counter-current chromatography].	Se pu = Chinese journal of chromatography 20080701
Role of Bax in quercetin-induced apoptosis in human prostate cancer cells.	Biochemical pharmacology 20080615
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).	Journal of medicinal chemistry 20080612
Flavones and flavonols exert cytotoxic effects on a human oesophageal adenocarcinoma cell line (OE33) by causing G2/M arrest and inducing apoptosis.	Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080601
Investigations on the fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene by certain flavonoids.	Journal of photochemistry and photobiology. B, Biology 20080529
Assessment of luteolin (3',4',5,7-tetrahydroxyflavone) neuropharmacological activity.	Behavioural brain research 20080516
Quercetin decreases intracellular GSH content and potentiates the apoptotic action of the antileukemic drug arsenic trioxide in human leukemia cell lines.	Biochemical pharmacology 20080515
Aromatase inhibition by synthetic lactones and flavonoids in human placental microsomes and breast fibroblasts--a comparative study.	Toxicology and applied pharmacology 20080501
Chrysin, a natural flavonoid enhances steroidogenesis and steroidogenic acute regulatory protein gene expression in mouse Leydig cells.	The Journal of endocrinology 20080501
Flavonoids-induced accumulation of hypoxia-inducible factor (HIF)-1alpha/2alpha is mediated through chelation of iron.	Journal of cellular biochemistry 20080415
Signal molecules in the peanut-bradyrhizobia interaction.	Archives of microbiology 20080401
Microbial metabolism part 9. Structure and antioxidant significance of the metabolites of 5,7-dihydroxyflavone (chrysin), and 5- and 6-hydroxyflavones.	Chemical & pharmaceutical bulletin 20080401
Phytoestrogens and breast cancer prevention: possible mechanisms of action.	Environmental health perspectives 20080401
The effects of chrysin, a Passiflora incarnata extract, on natural killer cell activity in male Sprague-Dawley rats undergoing abdominal surgery.	AANA journal 20080401
Flavonoids diosmetin and luteolin inhibit midazolam metabolism by human liver microsomes and recombinant CYP 3A4 and CYP3A5 enzymes.	Biochemical pharmacology 20080315
Pharmacological studies on hypotensive, diuretic and vasodilator activities of chrysin glucoside from Calycotome villosa in rats.	Phytotherapy research : PTR 20080301
Synthesis and biological evaluation of novel 8-aminomethylated oroxylin A analogues as alpha-glucosidase inhibitors.	Bioorganic & medicinal chemistry letters 20080301
Effects of Food Natural Products on the Biotransformation of PCBs.	Environmental toxicology and pharmacology 20080301
Complexation of flavonoids with iron: structure and optical signatures.	The journal of physical chemistry. B 20080214
Cytotoxic effects of the dietary flavones chrysin and apigenin in a normal trout liver cell line.	Chemico-biological interactions 20080110
Behavioral effects of 6-bromoflavanone and 5-methoxy-6,8-dibromoflavanone as anxiolytic compounds.	Progress in neuro-psychopharmacology & biological psychiatry 20080101
Evaluation of the radioprotective effects of propolis and flavonoids in gamma-irradiated mice: the alkaline comet assay study.	Biological & pharmaceutical bulletin 20080101
Reversal of multidrug resistance by synthetic and natural compounds in drug-resistant MCF-7 cell lines.	Chemotherapy 20080101
Activated PPARgamma Targets Surface and Intracellular Signals That Inhibit the Proliferation of Lung Carcinoma Cells.	PPAR research 20080101
Common dietary flavonoids inhibit the growth of the intraerythrocytic malaria parasite.	BMC research notes 20080101
Jaceosidin induces apoptosis in human ovary cancer cells through mitochondrial pathway.	Journal of biomedicine & biotechnology 20080101
PPARgamma: The Portrait of a Target Ally to Cancer Chemopreventive Agents.	PPAR research 20080101
Synthesis and enantiomeric resolution of (+/-)-pinocembrin.	Journal of Asian natural products research 20080101
Inflammaging as a prodrome to Alzheimer's disease.	Journal of neuroinflammation 20080101
Lipopolysaccharide (LPS) potentiates hydrogen peroxide toxicity in T98G astrocytoma cells by suppression of anti-oxidative and growth factor gene expression.	BMC genomics 20080101
Influence of some bioflavonoids on the transport of nitrendipine.	Drug metabolism and drug interactions 20080101
Plasma, tissue and urinary levels of aloin in rats after the administration of pure aloin.	Nutrition research and practice 20080101
[Effects of flavonoids with different structures on proliferation of leukemia cell line HL-60].	Ai zheng = Aizheng = Chinese journal of cancer 20071201
Iron-binding properties of plant phenolics and cranberry's bio-effects.	Dalton transactions (Cambridge, England : 2003) 20071121
Enzymatic acylation of flavonoids: effect of the nature of the substrate, origin of lipase, and operating conditions on conversion yield and regioselectivity.	Journal of agricultural and food chemistry 20071114
Analysis of the polyphenolic fraction of propolis from different sources by liquid chromatography-tandem mass spectrometry.	Journal of pharmaceutical and biomedical analysis 20071105
Sonoran propolis: chemical composition and antiproliferative activity on cancer cell lines.	Planta medica 20071101
Effect of 7-O-beta-D-glucopyranosylchrysin and its aglycone chrysin isolated from Podocytisus caramanicus on estrogen receptor alpha transcriptional activity.	Planta medica 20071101
Dietary flavonoid apigenin is a potential inducer of intracellular oxidative stress: the role in the interruptive apoptotic signal.	Archives of biochemistry and biophysics 20071015
Flavonoids induce germination of basidiospores of the ectomycorrhizal fungus Suillus bovinus.	Mycorrhiza 20071001
Comparative molecular field analysis of flavonoid inhibitors of the PIM-1 kinase.	Bioorganic & medicinal chemistry 20071001
Determination of flavonoid aglycones in several food samples by mixed micellar electrokinetic chromatography.	Journal of separation science 20071001
Evaluation of the anxiolytic effects of chrysin, a Passiflora incarnata extract, in the laboratory rat.	AANA journal 20071001
2-Styrylchromones: novel strong scavengers of reactive oxygen and nitrogen species.	Bioorganic & medicinal chemistry 20070915
Dietary flavones suppresses IgE and Th2 cytokines in OVA-immunized BALB/c mice.	European journal of nutrition 20070801
Wogonin but not Nor-wogonin inhibits lipopolysaccharide and lipoteichoic acid-induced iNOS gene expression and NO production in macrophages.	International immunopharmacology 20070801
Induction of apoptosis of human gastric carcinoma SGC-7901 cell line by 5, 7-dihydroxy-8-nitrochrysin in vitro.	World journal of gastroenterology 20070728
Chrysin inhibited stem cell factor (SCF)/c-Kit complex-induced cell proliferation in human myeloid leukemia cells.	Biochemical pharmacology 20070715
Computational studies of the binding mechanism of calmodulin with chrysin.	Biochemical and biophysical research communications 20070713
Selected flavonoids potentiate the toxicity of cisplatin in human lung adenocarcinoma cells: a role for glutathione depletion.	International journal of oncology 20070701
Effect of chrysin and natural coumarins on UGT1A1 and 1A6 activities in rat and human hepatocytes in primary culture.	Planta medica 20070701
(Anti)estrogenic effects of phytochemicals on human primary mammary fibroblasts, MCF-7 cells and their co-culture.	Toxicology and applied pharmacology 20070615
Interaction of flavonoids with red blood cell membrane lipids and proteins: antioxidant and antihemolytic effects.	International journal of biological macromolecules 20070601
The effect of flavones and flavonols on colonization of tomato plants by arbuscular mycorrhizal fungi of the genera Gigaspora and Glomus.	Canadian journal of microbiology 20070601
Cancer chemopreventive properties of orally bioavailable flavonoids--methylated versus unmethylated flavones.	Biochemical pharmacology 20070501
Reversal of inflammation-associated dihydrodiol dehydrogenases (AKR1C1 and AKR1C2) overexpression and drug resistance in nonsmall cell lung cancer cells by wogonin and chrysin.	International journal of cancer 20070501
Variable sulfation of dietary polyphenols by recombinant human sulfotransferase (SULT) 1A1 genetic variants and SULT1E1.	Drug metabolism and disposition: the biological fate of chemicals 20070501
An antifungal compound involved in symbiotic germination of Cypripedium macranthos var. rebunense (Orchidaceae).	Phytochemistry 20070501
Assessment by survival analysis of the radioprotective properties of propolis and its polyphenolic compounds.	Biological & pharmaceutical bulletin 20070501
[Synthesis of chrysin derivatives and their interaction with DNA].	Yao xue xue bao = Acta pharmaceutica Sinica 20070501
Phytochemicals induce breast cancer resistance protein in Caco-2 cells and enhance the transport of benzo[a]pyrene-3-sulfate.	Toxicological sciences : an official journal of the Society of Toxicology 20070401
Rational design of novel, potent small molecule pan-selectin antagonists.	Journal of medicinal chemistry 20070322
Identification of kaempferol as an inhibitor of cigarette smoke-induced activation of the aryl hydrocarbon receptor and cell transformation.	Carcinogenesis 20070301
Structure activity relationship of antioxidative property of flavonoids and inhibitory effect on matrix metalloproteinase activity in UVA-irradiated human dermal fibroblast.	Archives of pharmacal research 20070301
Antioxidant compounds of propolis determined by capillary electrophoresis-mass spectrometry.	Journal of separation science 20070301
Effects of the flavonoid chrysin on nitrofurantoin pharmacokinetics in rats: potential involvement of ABCG2.	Drug metabolism and disposition: the biological fate of chemicals 20070201
Flavonoids modulate monocarboxylate transporter-1-mediated transport of gamma-hydroxybutyrate in vitro and in vivo.	Drug metabolism and disposition: the biological fate of chemicals 20070201
The role of chrysin and the ah receptor in induction of the human UGT1A1 gene in vitro and in transgenic UGT1 mice.	Hepatology (Baltimore, Md.) 20070201
Structure-proteasome-inhibitory activity relationships of dietary flavonoids in human cancer cells.	Frontiers in bioscience : a journal and virtual library 20070101
Chrysin inhibits expression of hypoxia-inducible factor-1alpha through reducing hypoxia-inducible factor-1alpha stability and inhibiting its protein synthesis.	Molecular cancer therapeutics 20070101
In vitro antimicrobial activity of propolis samples from different geographical origins against certain oral pathogens.	Anaerobe 20070101
[Studies on chemical components of Cirsium segestum].	Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070101
[The estimation of biological value and quality of propolis and propolis based food products and food dietary supplements].	Voprosy pitaniia 20070101
The flavonoid luteolin worsens chemical-induced colitis in NF-kappaB(EGFP) transgenic mice through blockade of NF-kappaB-dependent protective molecules.	PloS one 20070101
Evaluation of propolis polyphenols absorption in humans by liquid chromatography/tandem mass spectrometry.	Rapid communications in mass spectrometry : RCM 20070101
Peroxisome proliferator-activated receptors in lung cancer.	PPAR research 20070101
Estrogenic activity of the chlorinated derivatives of estrogens and flavonoids using a GFP expression system.	Environmental toxicology and pharmacology 20070101
Dietary flavonoids attenuate tumor necrosis factor alpha-induced adhesion molecule expression in human aortic endothelial cells. Structure-function relationships and activity after first pass metabolism.	The Journal of biological chemistry 20061201
Accumulation and metabolism of the anticancer flavonoid 5,7-dimethoxyflavone compared to its unmethylated analog chrysin in the Atlantic killifish.	Chemico-biological interactions 20061201
Toxicological aspects of flavonoid interaction with biomacromolecules.	Neuro endocrinology letters 20061201
Quercetin, a flavonoid, inhibits proliferation and increases osteogenic differentiation in human adipose stromal cells.	Biochemical pharmacology 20061115
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.	Journal of molecular graphics & modelling 20061101
Oxidant/antioxidant properties of Croatian native propolis.	Journal of agricultural and food chemistry 20061018
Inhibition of pro-inflammatory markers in primary bone marrow-derived mouse macrophages by naturally occurring flavonoids: analysis of the structure-activity relationship.	Biochemical pharmacology 20061016
Gateways to clinical trials.	Methods and findings in experimental and clinical pharmacology 20061001
Analysis of flavonoids from propolis by on-line HPLC-electrospray mass spectrometry.	Journal of pharmaceutical and biomedical analysis 20060926
Aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha in MCF-7 breast cancer cells.	Biological chemistry 20060901
Modulation of activator protein-1 (AP-1) and MAPK pathway by flavonoids in human prostate cancer PC3 cells.	Archives of pharmacal research 20060801
Retention behavior of silica-bonded and novel polymeric reversed-phase sorbents in studies on flavones as chemotaxonomic markers of Scutellaria L. genus.	Journal of chromatography. A 20060707
Flavonoid-induced glutathione depletion: potential implications for cancer treatment.	Free radical biology & medicine 20060701
Combinatorial biosynthesis of flavones and flavonols in Escherichia coli.	Applied microbiology and biotechnology 20060601
Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids.	Journal of medicinal chemistry 20060601
Chrysin inhibits lipopolysaccharide-induced angiogenesis via down-regulation of VEGF/VEGFR-2(KDR) and IL-6/IL-6R pathways.	Planta medica 20060601
Modulation of aromatase activity by diet polyphenolic compounds.	Journal of agricultural and food chemistry 20060517
Antitumor activity of some natural flavonoids and synthetic derivatives on various human and murine cancer cell lines.	Bioorganic & medicinal chemistry 20060501
Preventive effects of chrysin on the development of azoxymethane-induced colonic aberrant crypt foci in rats.	Oncology reports 20060501
Microsphere-based protease assays and screening application for lethal factor and factor Xa.	Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Dietary flavonoids: effects on xenobiotic and carcinogen metabolism.	Toxicology in vitro : an international journal published in association with BIBRA 20060301
Cyanobacterial chemotaxis to extracts of host and nonhost plants.	FEMS microbiology ecology 20060301
Effect of different flavonoids on collagen synthesis in human fibroblasts.	Plant foods for human nutrition (Dordrecht, Netherlands) 20060301
A pilot study on the safety of combining chrysin, a non-absorbable inducer of UGT1A1, and irinotecan (CPT-11) to treat metastatic colorectal cancer.	Cancer chemotherapy and pharmacology 20060201
Synthesis and biological evaluation of novel C (7) modified chrysin analogues as antibacterial agents.	Bioorganic & medicinal chemistry letters 20060101
Use of the pig caecum model to mimic the human intestinal metabolism of hispidulin and related compounds.	Molecular nutrition & food research 20060101
Biosynthesis of isoprenoids, polyunsaturated fatty acids and flavonoids in Saccharomyces cerevisiae.	Microbial cell factories 20060101
Differential UGT1A1 induction by chrysin in primary human hepatocytes and HepG2 Cells.	The Journal of pharmacology and experimental therapeutics 20051201
Bcl-2 attenuates anticancer agents-induced apoptosis by sustained activation of Akt/protein kinase B in U937 cells.	Apoptosis : an international journal on programmed cell death 20051201
Biflavonoids from Lonicera japonica.	Phytochemistry 20051201
Structural basis of inhibitor specificity of the human protooncogene proviral insertion site in moloney murine leukemia virus (PIM-1) kinase.	Journal of medicinal chemistry 20051201
Determination of the overlapping pK(a) values of chrysin using UV-vis spectroscopy and ab initio methods.	Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20051101
Antiherpetic activities of flavonoids against herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) in vitro.	Archives of pharmacal research 20051101
Water-soluble derivative of propolis and its polyphenolic compounds enhance tumoricidal activity of macrophages.	Journal of ethnopharmacology 20051031
Molecular targets of dietary polyphenols with anti-inflammatory properties.	Yonsei medical journal 20051031
Differential modulation of ochratoxin A absorption across Caco-2 cells by dietary polyphenols, used at realistic intestinal concentrations.	Toxicology letters 20051015
Effects of hydroxyl group numbers on the B-ring of 5,7-dihydroxyflavones on the differential inhibition of human CYP 1A and CYP1B1 enzymes.	Archives of pharmacal research 20051001
Phytoestrogens as inhibitors of fungal 17beta-hydroxysteroid dehydrogenase.	Steroids 20050901
Synthesis and inhibition of PGE2 production of 6,8-disubstituted chrysin derivatives.	European journal of medicinal chemistry 20050901
Endothelial nitric oxide production stimulated by the bioflavonoid chrysin in rat isolated aorta.	Planta medica 20050901
Phytoestrogens as inhibitors of fungal 17beta-hydroxysteroid dehydrogenase.	Steroids 20050801
Structure and antiinflammatory activity relationships of wogonin derivatives.	Archives of pharmacal research 20050801
Human NAD(P)H:quinone oxidoreductase inhibition by flavonoids in living cells.	Free radical biology & medicine 20050715
Flavonoids exhibit fungal species and genus specific effects on the presymbiotic growth of Gigaspora and Glomus.	Mycological research 20050701
Chrysin induces G1 phase cell cycle arrest in C6 glioma cells through inducing p21Waf1/Cip1 expression: involvement of p38 mitogen-activated protein kinase.	Biochemical pharmacology 20050615
Biotransformation of chrysin and apigenin by Cunninghamella elegans.	Chemical & pharmaceutical bulletin 20050601
Synthesis and iNOS inhibitory activities of thioflavones.	Archives of pharmacal research 20050601
Human gut microbial degradation of flavonoids: structure-function relationships.	Journal of agricultural and food chemistry 20050518
Production of cytokine and NO by RAW 264.7 macrophages and PBMC in vitro incubation with flavonoids.	Archives of pharmacal research 20050501
Effects of flavonoids on cell proliferation and caspase activation in a human colonic cell line HT29: an SAR study.	Journal of medicinal chemistry 20050421
Stability of ferric complexes with 3-hydroxyflavone (flavonol), 5,7-dihydroxyflavone (chrysin), and 3',4'-dihydroxyflavone.	Journal of agricultural and food chemistry 20050420
A sensitive method for determination of COL-3, a chemically modified tetracycline, in human plasma using high-performance liquid chromatography and ultraviolet detection.	Journal of pharmaceutical and biomedical analysis 20050401
Synergistic antitumor effect of polyphenolic components of water soluble derivative of propolis against Ehrlich ascites tumour.	Biological & pharmaceutical bulletin 20050401
[Isolation and structure identification of chemical constituents from Viscum liquidambaricolum].	Yao xue xue bao = Acta pharmaceutica Sinica 20050401
Flavonoids from the leaves of Litsea japonica and their anti-complement activity.	Phytotherapy research : PTR 20050401
Expression profiling of the estrogen responsive genes in response to phytoestrogens using a customized DNA microarray.	FEBS letters 20050314
Kinetic study of the quenching reaction of singlet oxygen by flavonoids in ethanol solution.	The journal of physical chemistry. B 20050310
Flavones suppress the expression of the high-affinity IgE receptor FcepsilonRI in human basophilic KU812 cells.	Journal of agricultural and food chemistry 20050309
Flavonoids chrysin and benzoflavone, potent breast cancer resistance protein inhibitors, have no significant effect on topotecan pharmacokinetics in rats or mdr1a/1b (-/-) mice.	Drug metabolism and disposition: the biological fate of chemicals 20050301
Cell-based high-throughput bioassays to assess induction and inhibition of CYP1A enzymes.	Toxicology in vitro : an international journal published in association with BIBRA 20050301
[Xanthine oxidase inhibitory activity and hypouricemia effect of propolis in rats].	Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20050301
Crystal structure of a human cyclin-dependent kinase 6 complex with a flavonol inhibitor, fisetin.	Journal of medicinal chemistry 20050210
[Studies on chemical constituents from Elsholtzia bodinieri Vaniot].	Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20050201
Chrysin suppresses lipopolysaccharide-induced cyclooxygenase-2 expression through the inhibition of nuclear factor for IL-6 (NF-IL6) DNA-binding activity.	FEBS letters 20050131
Comparison of high-speed counter-current chromatography instruments for the separation of the extracts of the seeds of Oroxylum indicum.	Journal of chromatography. A 20050121
Decreased pro-inflammatory cytokine production by LPS-stimulated PBMC upon in vitro incubation with the flavonoids apigenin, luteolin or chrysin, due to selective elimination of monocytes/macrophages.	Biochemical pharmacology 20050115
Dietary polyphenols protect dopamine neurons from oxidative insults and apoptosis: investigations in primary rat mesencephalic cultures.	Biochemical pharmacology 20050115
Analysis of substrate specificities and tissue expression of rat UDP-glucuronosyltransferases UGT1A7 and UGT1A8.	Drug metabolism and disposition: the biological fate of chemicals 20050101
Baicalein protects rat cardiomyocytes from hypoxia/reoxygenation damage via a prooxidant mechanism.	Cardiovascular research 20050101
In vitro digestion and lactase treatment influence uptake of quercetin and quercetin glucoside by the Caco-2 cell monolayer.	Nutrition journal 20050101
Determination of six kavalactones in dietary supplements and selected functional foods containing Piper methysticum by isocratic liquid chromatography with internal standard.	Journal of AOAC International 20050101
Comparative effects of fibrates on drug metabolizing enzymes in human hepatocytes.	Pharmaceutical research 20050101
In vitro search for synergy between flavonoids and epirubicin on multidrug-resistant cancer cells.	In vivo (Athens, Greece) 20050101
Chemical compositions and antimicrobial activities of four different Anatolian propolis samples.	Microbiological research 20050101
The effects of dietary phytoestrogens on aromatase activity in human endometrial stromal cells.	Reproduction, nutrition, development 20050101
Chrysin-induced apoptosis is mediated through caspase activation and Akt inactivation in U937 leukemia cells.	Biochemical and biophysical research communications 20041224
Evaluation of the first-pass glucuronidation of selected flavones in gut by Caco-2 monolayer model.	Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20041220
A photoaffinity probe designed for host-specific signal flavonoid receptors in phytopathogenic Peronosporomycete zoospores of Aphanomyces cochlioides.	Archives of biochemistry and biophysics 20041215
Chrysin and its phosphate ester inhibit cell proliferation and induce apoptosis in Hela cells.	Bioorganic & medicinal chemistry 20041201
Induction and inhibition of aromatase (CYP19) activity by natural and synthetic flavonoid compounds in H295R human adrenocortical carcinoma cells.	Toxicological sciences : an official journal of the Society of Toxicology 20041101
A UV resonance Raman (UVRR) spectroscopic study on the extractable compounds in Scots pine (Pinus sylvestris) wood. Part II. Hydrophilic compounds.	Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20041101
Vascular and anti-oxidant actions of flavonols and flavones.	Clinical and experimental pharmacology & physiology 20041101
Phytochemicals inhibit catechol-O-methyltransferase activity in cytosolic fractions from healthy human mammary tissues: implications for catechol estrogen-induced DNA damage.	Toxicological sciences : an official journal of the Society of Toxicology 20041001
Vasorelaxing effects of flavonoids: investigation on the possible involvement of potassium channels.	Naunyn-Schmiedeberg's archives of pharmacology 20041001
Dietary polyphenols (-)-epicatechin and chrysin inhibit intestinal glucuronidation metabolism to increase drug absorption.	Journal of pharmaceutical sciences 20040901
Flavonoids inhibit tumor necrosis factor-alpha-induced up-regulation of intercellular adhesion molecule-1 (ICAM-1) in respiratory epithelial cells through activator protein-1 and nuclear factor-kappaB: structure-activity relationships.	Molecular pharmacology 20040901
Inhibitory effect of flavonoids on N-acetylation of 5-aminosalicylic acid in cultured rat hepatocytes.	Biological & pharmaceutical bulletin 20040901
The pig caecum model: a suitable tool to study the intestinal metabolism of flavonoids.	Molecular nutrition & food research 20040901
Synthesis and biological evaluation of flavonoids as vasorelaxant agents.	Bioorganic & medicinal chemistry letters 20040802
Structural and spectroscopic study of 5,7-dihydroxy-flavone and its complex with aluminum.	Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040801
Electrospray ionization mass spectrometry fingerprinting of propolis.	The Analyst 20040801
Synthesis and aromatase inhibitory activity of novel pyridine-containing isoflavones.	Journal of medicinal chemistry 20040729
Effect of flavonoids and vitamin E on cyclooxygenase-2 (COX-2) transcription.	Mutation research 20040713
Combined effects of multiple flavonoids on breast cancer resistance protein (ABCG2)-mediated transport.	Pharmaceutical research 20040701
Phytoestrogens/flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance.	Cancer research 20040615
Determination of SU5416, a novel angiogenesis inhibitor, in human plasma by liquid chromatography.	Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040605
Separation of flavonoids and phenolic acids from propolis by capillary zone electrophoresis.	Electrophoresis 20040601
Investigation of the membrane localization and distribution of flavonoids by high-resolution magic angle spinning NMR spectroscopy.	Biochimica et biophysica acta 20040527
Identification of metabolites in plasma and urine of Uruguayan propolis-treated rats.	Journal of agricultural and food chemistry 20040519
Neuroprotective effects of flavones on hydrogen peroxide-induced apoptosis in SH-SY5Y neuroblostoma cells.	Bioorganic & medicinal chemistry letters 20040503
Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport.	Molecular pharmacology 20040501
Inhibitory effect of flavonoids on sulfo- and glucurono-conjugation of acetaminophen in rat cultured hepatocytes and liver subcellular preparations.	Biological & pharmaceutical bulletin 20040501
Antioxidative bioavailability of artepillin C in Brazilian propolis.	Archives of biochemistry and biophysics 20040415
Synthesis and inhibitory activity against COX-2 catalyzed prostaglandin production of chrysin derivatives.	Bioorganic & medicinal chemistry letters 20040308
Effects of ethanol extract of propolis (EEP) and its flavones on inducible gene expression in J774A.1 macrophages.	Journal of ethnopharmacology 20040301
Synthesis and biological activities of 8-arylflavones.	Archives of pharmacal research 20040301
The induction of human UDP-glucuronosyltransferase 1A1 mediated through a distal enhancer module by flavonoids and xenobiotics.	Biochemical pharmacology 20040301
Quantitative high-performance liquid chromatography analyses of flavonoids in Australian Eucalyptus honeys.	Journal of agricultural and food chemistry 20040128
Differential and special properties of the major human UGT1-encoded gastrointestinal UDP-glucuronosyltransferases enhance potential to control chemical uptake.	The Journal of biological chemistry 20040109
Antiproliferative activity of various flavonoids and related compounds: additive effect of interferon-alpha2b.	Bioorganic & medicinal chemistry letters 20040105
Modulation of the activity of pro-inflammatory enzymes, COX-2 and iNOS, by chrysin derivatives.	Pharmacological research 20040101
Antioxidant capacity of reaction products limits the applicability of the Trolox Equivalent Antioxidant Capacity (TEAC) assay.	Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040101
The nature of phosphorylated chrysin-protein interactions involved in noncovalent complex formation by electrospray ionization mass spectroscopy.	Analytical chemistry 20040101
A hydroxyl group of flavonoids affects oral anti-inflammatory activity and inhibition of systemic tumor necrosis factor-alpha production.	Bioscience, biotechnology, and biochemistry 20040101
Individual and interactive effects of apigenin analogs on G2/M cell-cycle arrest in human colon carcinoma cell lines.	Nutrition and cancer 20040101
Effects of the dietary flavonoid chrysin in isolated rat mesenteric vascular bed.	Journal of vascular research 20040101
Flavonoids induce apoptosis in human leukemia U937 cells through caspase- and caspase-calpain-dependent pathways.	Nutrition and cancer 20040101
Constituents of Quinchamalium majus with potential antitubercular activity.	Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101

Restorative effects of Chrysin pretreatment on oxidant-antioxidant status, inflammatory cytokine production, and apoptotic and autophagic markers in acute paracetamol-induced hepatotoxicity in rats: An experimental and biochemical study.

Journal of biochemical and molecular toxicology 20171101

Chrysin and silibinin sensitize human glioblastoma cells for arsenic trioxide.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20170701

Chrysin, a PPAR-γ agonist improves myocardial injury in diabetic rats through inhibiting AGE-RAGE mediated oxidative stress and inflammation.

Chemico-biological interactions 20160425

3-Methyl-4,5-dihydro-oxepine, polyoxygenated seco-cyclohexenes and cyclohexenes from Uvaria flexuosa and their anti-inflammatory activity.

Phytochemistry 20160201

Flavonoids suppress human glioblastoma cell growth by inhibiting cell metabolism, migration, and by regulating extracellular matrix proteins and metalloproteinases expression.

Chemico-biological interactions 20151205

Chrysin attenuates liver fibrosis and hepatic stellate cell activation through TGF-β/Smad signaling pathway.

Chemico-biological interactions 20151005

Combination of chrysin and cisplatin promotes the apoptosis of Hep G2 cells by up-regulating p53.

Chemico-biological interactions 20150505

Chrysin, baicalein and galangin are indirect activators of the human constitutive androstane receptor (CAR).

Toxicology letters 20150304

Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and α-fetoprotein.

Toxicological sciences : an official journal of the Society of Toxicology 20150201

Investigation of the effects of some phenolic compounds on the activities of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase from human erythrocytes.

Journal of biochemical and molecular toxicology 20141101

Chrysin alleviates testicular dysfunction in adjuvant arthritic rats via suppression of inflammation and apoptosis: comparison with celecoxib.

Toxicology and applied pharmacology 20140901

Dietary flavonoids fisetin and myricetin: dual inhibitors of Plasmodium falciparum falcipain-2 and plasmepsin II.

Fitoterapia 20140401

7,8-Dihydroxyflavone, a TrkB agonist, attenuates behavioral abnormalities and neurotoxicity in mice after administration of methamphetamine.

Psychopharmacology 20140101

Chrysin inhibits metastatic potential of human triple-negative breast cancer cells by modulating matrix metalloproteinase-10, epithelial to mesenchymal transition, and PI3K/Akt signaling pathway.

Journal of applied toxicology : JAT 20140101

Chrysin and luteolin alleviate vascular complications associated with insulin resistance mainly through PPAR-γ activation.

The American journal of Chinese medicine 20140101

Quantitative high-throughput profiling of environmental chemicals and drugs that modulate farnesoid X receptor.

Scientific reports 20140101

The O-methylation of chrysin markedly improves its intestinal anti-inflammatory properties: Structure-activity relationships of flavones.

Biochemical pharmacology 20131215

Chrysin enhances sensitivity of BEL-7402/ADM cells to doxorubicin by suppressing PI3K/Akt/Nrf2 and ERK/Nrf2 pathway.

Chemico-biological interactions 20131025

Pyranoflavones: a group of small-molecule probes for exploring the active site cavities of cytochrome P450 enzymes 1A1, 1A2, and 1B1.

Journal of medicinal chemistry 20130523

Chrysin suppresses renal carcinogenesis via amelioration of hyperproliferation, oxidative stress and inflammation: plausible role of NF-κB.

Toxicology letters 20130204

Protection by chrysin, apigenin, and luteolin against oxidative stress is mediated by the Nrf2-dependent up-regulation of heme oxygenase 1 and glutamate cysteine ligase in rat primary hepatocytes.

Archives of toxicology 20130101

Rat α-Fetoprotein binding affinities of a large set of structurally diverse chemicals elucidated the relationships between structures and binding affinities.

Chemical research in toxicology 20121119

Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Bioorganic & medicinal chemistry 20121115

Ameliorating effects of quercetin and chrysin on 2,3,7,8-tetrachlorodibenzo- p-dioxin-induced nephrotoxicity in rats.

Toxicology and industrial health 20121101

Simultaneous determination of baicalin, wogonoside, baicalein, wogonin, oroxylin A and chrysin of Radix scutellariae extract in rat plasma by liquid chromatography tandem mass spectrometry.

Journal of pharmaceutical and biomedical analysis 20121101

Drug screening study using glioma stem-like cells.

Molecular medicine reports 20121101

Induction of apoptosis by 7-piperazinethylchrysin in HCT-116 human colon cancer cells.

Oncology reports 20121101

Targeting tumor ubiquitin-proteasome pathway with polyphenols for chemosensitization.

Anti-cancer agents in medicinal chemistry 20121001

Protective role of chrysin against oxidative stress in d-galactose-induced aging in an experimental rat model.

Geriatrics & gerontology international 20121001

Evaluation of the structure-activity relationship of flavonoids as antioxidants and toxicants of zebrafish larvae.

Food chemistry 20120915

A flavonoid component from Docynia delavayi (Franch.) Schneid represses transplanted H22 hepatoma growth and exhibits low toxic effect on tumor-bearing mice.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120901

Simultaneous determination of active flavonoids and alkaloids of Tang-Min-Ling-Pill in rat plasma by liquid chromatography tandem mass spectrometry.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120901

AMP-activated protein kinase (AMPK) activation is involved in chrysin-induced growth inhibition and apoptosis in cultured A549 lung cancer cells.

Biochemical and biophysical research communications 20120706

Phytochemical and antimicrobial investigations of stilbenoids and flavonoids isolated from three species of Combretaceae.

Fitoterapia 20120701

Chrysin attenuates allergic airway inflammation by modulating the transcription factors T-bet and GATA-3 in mice.

Molecular medicine reports 20120701

Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13.

Bioorganic & medicinal chemistry letters 20120615

Beneficial effects of chrysin on the reproductive system of adult male rats.

Andrologia 20120601

Chrysin restores PDGF-induced inhibition on protein tyrosine phosphatase and reduces PDGF signaling in cultured VSMCs.

The Journal of nutritional biochemistry 20120601

Discovery of flavonoid derivatives as anti-HCV agents via pharmacophore search combining molecular docking strategy.

European journal of medicinal chemistry 20120601

Nephroprotective efficacy of chrysin against cisplatin-induced toxicity via attenuation of oxidative stress.

The Journal of pharmacy and pharmacology 20120601

Inhibitory effects of dietary flavonoids on purified hepatic NADH-cytochrome b5 reductase: structure-activity relationships.

Chemico-biological interactions 20120530

Differential effects of flavonoids on barrier integrity in human intestinal Caco-2 cells.

Journal of agricultural and food chemistry 20120509

Mutagenicity of flavonoids assayed by bacterial reverse mutation (Ames) test.

Molecules (Basel, Switzerland) 20120507

Characterization of phenolic compounds in flowers of wild medicinal plants from Northeastern Portugal.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120501

Optimized assays for human UDP-glucuronosyltransferase (UGT) activities: altered alamethicin concentration and utility to screen for UGT inhibitors.

Drug metabolism and disposition: the biological fate of chemicals 20120501

Flavones and structurally related 4-chromenones inhibit carbonic anhydrases by a different mechanism of action compared to coumarins.

Bioorganic & medicinal chemistry letters 20120501

Inhibitory effects of acetylmelodorinol, chrysin and polycarpol from Mitrella kentii on prostaglandin E₂ and Thromboxane B₂ production and platelet activating factor receptor binding.

Molecules (Basel, Switzerland) 20120426

The anticancer activity of propolis.

Folia histochemica et cytobiologica 20120424

Development of a new class of aromatase inhibitors: design, synthesis and inhibitory activity of 3-phenylchroman-4-one (isoflavanone) derivatives.

Bioorganic & medicinal chemistry 20120415

Chrysin improves cognitive deficits and brain damage induced by chronic cerebral hypoperfusion in rats.

European journal of pharmacology 20120405

Methylated chrysin reduced cell proliferation, but antagonized cytotoxicity of other anticancer drugs in acute lymphoblastic leukemia.

Anti-cancer drugs 20120401

Glycosylation of various flavonoids by recombinant oleandomycin glycosyltransferase from Streptomyces antibioticus in batch and repeated batch modes.

Biotechnology letters 20120301

Bioassay-guided isolation of vasorelaxant compounds from Ziziphora clinopodioides Lam. (Lamiaceae).

Fitoterapia 20120301

Regulation of NF-κB activity in astrocytes: effects of flavonoids at dietary-relevant concentrations.

Biochemical and biophysical research communications 20120217

Molecular structure and vibrational spectroscopic studies of Chrysin using HF and Density Functional Theory.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120215

Chrysin protects against cisplatin-induced colon. toxicity via amelioration of oxidative stress and apoptosis: probable role of p38MAPK and p53.

Toxicology and applied pharmacology 20120201

Molecular dynamic behavior and binding affinity of flavonoid analogues to the cyclin dependent kinase 6/cyclin D complex.

Journal of chemical information and modeling 20120123

Induction of oxidative DNA damage by flavonoids of propolis: its mechanism and implication about antioxidant capacity.

Chemical research in toxicology 20120113

Dual protective effect of Passiflora incarnata in epilepsy and associated post-ictal depression.

Journal of ethnopharmacology 20120106

Wogonin and related natural flavones overcome tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein resistance of tumors by down-regulation of c-FLIP protein and up-regulation of TRAIL receptor 2 expression.

The Journal of biological chemistry 20120102

Ethanolic extract of fructus Alpinia oxyphylla protects against 6-hydroxydopamine-induced damage of PC12 cells in vitro and dopaminergic neurons in zebrafish.

Cellular and molecular neurobiology 20120101

¹H-NMR simultaneous identification of health-relevant compounds in propolis extracts.

Phytochemical analysis : PCA 20120101

Chrysin enhances doxorubicin-induced cytotoxicity in human lung epithelial cancer cell lines: the role of glutathione.

Toxicology and applied pharmacology 20120101

Greco-arab and islamic herbal-derived anticancer modalities: from tradition to molecular mechanisms.

Evidence-based complementary and alternative medicine : eCAM 20120101

Luteolin Suppresses Inflammatory Mediator Expression by Blocking the Akt/NFκB Pathway in Acute Lung Injury Induced by Lipopolysaccharide in Mice.

Evidence-based complementary and alternative medicine : eCAM 20120101

A searchable cross-platform gene expression database reveals connections between drug treatments and disease.

BMC genomics 20120101

Effect of an Ethanol Extract of Scutellaria baicalensis on Relaxation in Corpus Cavernosum Smooth Muscle.

Evidence-based complementary and alternative medicine : eCAM 20120101

Molecular modeling study of chiral separation and recognition mechanism of β-adrenergic antagonists by capillary electrophoresis.

International journal of molecular sciences 20120101

A naturally occurring carotenoid, lutein, reduces PDGF and H₂O₂ signaling and compromised migration in cultured vascular smooth muscle cells.

Journal of biomedical science 20120101

Acute exposure of apigenin induces hepatotoxicity in Swiss mice.

PloS one 20120101

Role of transcription factors in peripheral nerve regeneration.

Frontiers in molecular neuroscience 20120101

Bufalin induces lung cancer cell apoptosis via the inhibition of PI3K/Akt pathway.

International journal of molecular sciences 20120101

AHR and the Transcriptional Regulation of Type-17/22 ILC.

Frontiers in immunology 20120101

Inhibitory effects and underlying mechanism of 7-hydroxyflavone phosphate ester in HeLa cells.

PloS one 20120101

Enzymatic modification of chitosan with quercetin and its application as antioxidant edible films.

Prikladnaia biokhimiia i mikrobiologiia 20120101

Plant HDAC inhibitor chrysin arrest cell growth and induce p21WAF1 by altering chromatin of STAT response element in A375 cells.

BMC cancer 20120101

Microbial transformations of 7-hydroxyflavanone.

TheScientificWorldJournal 20120101

Analgesic and Anti-Inflammatory Activities of Methanol Extract of Ficus pumila L. in Mice.

Evidence-based complementary and alternative medicine : eCAM 20120101

Limitations of inhibitory activities of polyphenols on furin-mediated substrate processing.

Current medicinal chemistry 20120101

A novel relationship between the radical-scavenging activity of flavonoids and enthalpy of formation revealed with Hartree-Fock computations and thermochemical deduction.

Redox report : communications in free radical research 20120101

Chrysin, a natural and biologically active flavonoid, influences a murine leukemia model in vivo through enhancing populations of T-and B-cells, and promoting macrophage phagocytosis and NK cell cytotoxicity.

In vivo (Athens, Greece) 20120101

Evaluation of the mutagenic activity of chrysin, a flavonoid inhibitor of the aromatization process.

Journal of toxicology and environmental health. Part A 20120101

Chemical compositions and antioxidant activities of water extracts of Chinese propolis.

Journal of agricultural and food chemistry 20111214

Chrysin protects mice from Staphylococcus aureus pneumonia.

Journal of applied microbiology 20111201

New synthetic anti-inflammatory chrysin analog, 5,7-dihydroxy-8-(pyridine-4yl)flavone.

European journal of pharmacology 20111130

Fast chromatographic separation for the quantitation of the main flavone dyes in Reseda luteola (weld).

Journal of chromatography. A 20111125

The anticancer flavonoid chrysin induces the unfolded protein response in hepatoma cells.

Journal of cellular and molecular medicine 20111101

Protective effect of chrysin on carbon tetrachloride (CCl4)-induced tissue injury in male Wistar rats.

Toxicology and industrial health 20111101

Hybrid flavan-chalcones, aromatase and lipoxygenase inhibitors, from Desmos cochinchinensis.

Phytochemistry 20111101

Investigations on membrane perturbation by chrysin and its copper complex using self-assembled lipid bilayers.

Langmuir : the ACS journal of surfaces and colloids 20111101

Ultra high performance liquid chromatography-time of flight mass spectrometry for analysis of avocado fruit metabolites: method evaluation and applicability to the analysis of ripening degrees.

Journal of chromatography. A 20111021

Potency of inhibition of human DNA topoisomerase I by flavones assessed through physicochemical parameters.

Free radical biology & medicine 20111001

Flavonoids in Scutellaria immaculata and S. ramosissima (Lamiaceae) and their biological activity.

The Journal of pharmacy and pharmacology 20111001

Protective effects of quercetin and chrysin against 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induced oxidative stress, body wasting and altered cytokine productions in rats.

Immunopharmacology and immunotoxicology 20110901

Antiproliferative effect of chrysin on anaplastic thyroid cancer.

The Journal of surgical research 20110901

A chrysin analog exhibited strong inhibitory activities against both PGE2 and NO production.

European journal of medicinal chemistry 20110901

Docking and 3D-QSAR (quantitative structure activity relationship) studies of flavones, the potent inhibitors of p-glycoprotein targeting the nucleotide binding domain.

European journal of medicinal chemistry 20110901

Potentiation of arsenic trioxide-induced apoptosis by 8-bromo-7-methoxychrysin in human leukemia cells involves depletion of intracellular reduced glutathione.

Acta biochimica et biophysica Sinica 20110901

Methylated chrysin induces co-ordinated attenuation of the canonical Wnt and NF-kB signaling pathway and upregulates apoptotic gene expression in the early hepatocarcinogenesis rat model.

Chemico-biological interactions 20110815

Chrysin protects epidermal keratinocytes from UVA- and UVB-induced damage.

Journal of agricultural and food chemistry 20110810

Inhibition of melanogenesis by 5,7-dihydroxyflavone (chrysin) via blocking adenylyl cyclase activity.

Biochemical and biophysical research communications 20110722

Chrysin suppresses mast cell-mediated allergic inflammation: involvement of calcium, caspase-1 and nuclear factor-κB.

Toxicology and applied pharmacology 20110701

Wogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis in cancer cells by transcriptional suppression of Mcl-1.

Cell death & disease 20110701

Resveratrol in combination with other dietary polyphenols concomitantly enhances antiproliferation and UGT1A1 induction in Caco-2 cells.

Life sciences 20110606

Chemical composition of the ethanolic propolis extracts and its effect on HeLa cells.

Journal of ethnopharmacology 20110601

Chrysin reduces proliferation and induces apoptosis in the human prostate cancer cell line pc-3.

Clinics (Sao Paulo, Brazil) 20110601

Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids.

Bioorganic & medicinal chemistry 20110501

Intrinsic and extrinsic regulation of innate immune receptors.

Yonsei medical journal 20110501

Anti-asthmatic potential of chrysin on ovalbumin-induced bronchoalveolar hyperresponsiveness in rats.

Pharmaceutical biology 20110501

Quercetin-iron chelates are transported via glucose transporters.

Free radical biology & medicine 20110415

Screening of bacterial cytochrome P450s responsible for regiospecific hydroxylation of (iso)flavonoids.

Enzyme and microbial technology 20110407

Chrysin promotes tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induced apoptosis in human cancer cell lines.

Toxicology in vitro : an international journal published in association with BIBRA 20110401

Can flavonoids from honey alter multidrug resistance?

Medical hypotheses 20110401

Structure-activity relationships of flavonoids as inhibitors of breast cancer resistance protein (BCRP).

Bioorganic & medicinal chemistry 20110315

Ultrasonic-assisted synthesis of chrysin derivatives linked with 1,2,3-triazoles by 1,3-dipolar cycloaddition reaction.

Ultrasonics sonochemistry 20110301

Chrysin abrogates early hepatocarcinogenesis and induces apoptosis in N-nitrosodiethylamine-induced preneoplastic nodules in rats.

Toxicology and applied pharmacology 20110215

Furoxan nitric oxide donor coupled chrysin derivatives: synthesis and vasculoprotection.

Bioorganic & medicinal chemistry letters 20110215

Chrysin-induced apoptosis is mediated through p38 and Bax activation in B16-F1 and A375 melanoma cells.

International journal of oncology 20110201

Chemopreventive effect of dietary polyphenols in colorectal cancer cell lines.

Nutrition research (New York, N.Y.) 20110201

Anticonvulsant and neurotoxicity profile of the rhizome of Smilax china Linn. in mice.

Indian journal of pharmacology 20110201

Ethanolic Extract of Propolis Augments TRAIL-Induced Apoptotic Death in Prostate Cancer Cells.

Evidence-based complementary and alternative medicine : eCAM 20110101

Effects of methimazole on the elimination of irinotecan.

Cancer chemotherapy and pharmacology 20110101

Ethanol extract of chinese propolis facilitates functional recovery of locomotor activity after spinal cord injury.

Evidence-based complementary and alternative medicine : eCAM 20110101

Suppressive Effect on Lipopolysaccharide-Induced Proinflammatory Mediators by Citrus aurantium L. in Macrophage RAW 264.7 Cells via NF-κB Signal Pathway.

Evidence-based complementary and alternative medicine : eCAM 20110101

Methylated chrysin, a dimethoxy flavone, partially suppresses the development of liver preneoplastic lesions induced by N-nitrosodiethylamine in rats.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110101

Concentration-Dependent Protection by Ethanol Extract of Propolis against γ-Ray-Induced Chromosome Damage in Human Blood Lymphocytes.

Evidence-based complementary and alternative medicine : eCAM 20110101

Inhibitory effect of chinese propolis on phosphatidylcholine-specific phospholipase C activity in vascular endothelial cells.

Evidence-based complementary and alternative medicine : eCAM 20110101

Apigenin inhibits tumor necrosis factor alpha plus high glucose-induced LOX-1 expression in human endothelial cells.

Microvascular research 20110101

Synthesis, biological evaluation of chrysin derivatives as potential immunosuppressive agents.

European journal of medicinal chemistry 20110101

In vitro studies on the inhibition of colon cancer by butyrate and polyphenolic compounds.

Nutrition and cancer 20110101

The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease.

International journal of molecular sciences 20110101

Facile synthesis of chrysin-derivatives with promising activities as aromatase inhibitors.

Natural product communications 20110101

Honey induces apoptosis in renal cell carcinoma.

Pharmacognosy magazine 20110101

Chrysin modulates ethanol metabolism in Wistar rats: a promising role against organ toxicities.

Alcohol and alcoholism (Oxford, Oxfordshire) 20110101

Novel natural inhibitors of CYP1A2 identified by in silico and in vitro screening.

International journal of molecular sciences 20110101

Efficacy of Brazilian Propolis against Herpes Simplex Virus Type 1 Infection in Mice and Their Modes of Antiherpetic Efficacies.

Evidence-based complementary and alternative medicine : eCAM 20110101

Elevated BCRP/ABCG2 expression confers acquired resistance to gefitinib in wild-type EGFR-expressing cells.

PloS one 20110101

Evaluation of antiaggregatory activity of flavonoid aglycone series.

Nutrition journal 20110101

Polyphenolic fraction of Algerian propolis protects rat kidney against acute oxidative stress induced by doxorubicin.

Indian journal of nephrology 20110101

Research strategies in the study of the pro-oxidant nature of polyphenol nutraceuticals.

Journal of toxicology 20110101

An integrated bioinformatics approach identifies elevated cyclin E2 expression and E2F activity as distinct features of tamoxifen resistant breast tumors.

PloS one 20110101

Development and validation of a UHPLC method for the determination of flavonoids in red wine.

Journal of AOAC International 20110101

5-allyl-7-gen-difluoromethoxychrysin enhances TRAIL-induced apoptosis in human lung carcinoma A549 cells.

BMC cancer 20110101

Teucrium plant species as natural sources of novel anticancer compounds: antiproliferative, proapoptotic and antioxidant properties.

International journal of molecular sciences 20110101

Structure of flavonoids influences the degree inhibition of Benzo(a)pyrene - induced DNA damage and micronuclei in HepG2 cells.

Neoplasma 20110101

Selection of herbal therapeutics against deltatoxin mediated Clostridial infections.

Bioinformation 20110101

Dietary α-eleostearic acid ameliorates experimental inflammatory bowel disease in mice by activating peroxisome proliferator-activated receptor-γ.

PloS one 20110101

Honey and renal cell carcinoma.

Pharmacognosy magazine 20110101

Antioxidant and potential anti-inflammatory activity of extracts and formulations of white tea, rose, and witch hazel on primary human dermal fibroblast cells.

Journal of inflammation (London, England) 20110101

Drug discovery for Duchenne muscular dystrophy via utrophin promoter activation screening.

PloS one 20110101

Pro-inflammatory gene expression and neurotoxic effects of activated microglia are attenuated by absence of CCAAT/enhancer binding protein β.

Journal of neuroinflammation 20110101

Antimutagenic and free radical scavenger effects of leaf extracts from Accacia salicina.

Annals of clinical microbiology and antimicrobials 20110101

Protective effect of aqueous extract of Oroxylum indicum Linn. (root bark) against DNBS-induced colitis in rats.

Indian journal of pharmacology 20110101

Inhibitors of alphavirus entry and replication identified with a stable Chikungunya replicon cell line and virus-based assays.

PloS one 20110101

Bioactive constituents and medicinal importance of genus Alnus.

Pharmacognosy reviews 20110101

A Review on the Taxonomy, Ethnobotany, Chemistry and Pharmacology of Oroxylum indicum Vent.

Indian journal of pharmaceutical sciences 20110101

Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives.

Chemical research in toxicology 20101220

Anti-inflammatory effects of dietary phenolic compounds in an in vitro model of inflamed human intestinal epithelium.

Chemico-biological interactions 20101205

Gene expression profiles in human peripheral blood mononuclear cells as biomarkers for nutritional in vitro and in vivo investigations.

Genes & nutrition 20101201

Chrysin suppresses LPS-stimulated proinflammatory responses by blocking NF-κB and JNK activations in microglia cells.

Neuroscience letters 20101126

Flavonoids from Halostachys caspica and their antimicrobial and antioxidant activities.

Molecules (Basel, Switzerland) 20101105

Antifilarial activity in vitro and in vivo of some flavonoids tested against Brugia malayi.

Acta tropica 20101101

Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Bioorganic & medicinal chemistry letters 20101101

Induction of apoptosis by 5,7-dihydroxy-8-nitrochrysin in breast cancer cells: the role of reactive oxygen species and Akt.

International journal of oncology 20101101

Synthesis and biological evaluation of novel benzyl-substituted flavones as free radical (DPPH) scavengers and α-glucosidase inhibitors.

Journal of Asian natural products research 20101101

Isoform-selective inhibition of chrysin towards human cytochrome P450 1A2. Kinetics analysis, molecular docking, and molecular dynamics simulations.

Bioorganic & medicinal chemistry letters 20101015

Multivariate QSAR study on the antimutagenic activity of flavonoids against 3-NFA on Salmonella typhimurium TA98.

European journal of medicinal chemistry 20101001

Inhibition of CCAAT/enhancer binding protein δ expression by chrysin in microglial cells results in anti-inflammatory and neuroprotective effects.

Journal of neurochemistry 20101001

Acacia honey and chrysin reduce proliferation of melanoma cells through alterations in cell cycle progression.

International journal of oncology 20101001

Separation optimization of quercetin, hesperetin and chrysin in honey by micellar liquid chromatography and experimental design.

Journal of separation science 20101001

Seasonal variation, chemical composition and antioxidant activity of Brazilian propolis samples.

Evidence-based complementary and alternative medicine : eCAM 20100901

Flavonoid combinations cause synergistic inhibition of proinflammatory mediator secretion from lipopolysaccharide-induced RAW 264.7 cells.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20100901

Effects of propolis from different areas on mast cell degranulation and identification of the effective components in propolis.

International immunopharmacology 20100901

Prenylflavonoids and prenyl/alkyl-phloroacetophenones: synthesis and antitumour biological evaluation.

European journal of medicinal chemistry 20100901

Selective inhibition of methoxyflavonoids on human CYP1B1 activity.

Bioorganic & medicinal chemistry 20100901

Ellagic acid, phenolic acids, and flavonoids in Malaysian honey extracts demonstrate in vitro anti-inflammatory activity.

Nutrition research (New York, N.Y.) 20100901

Chrysin blocks topotecan-induced apoptosis in Caco-2 cells in spite of inhibition of ABC-transporters.

Biochemical pharmacology 20100815

Role of oxidative stress in the antitumoral action of a new vanadyl(IV) complex with the flavonoid chrysin in two osteoblast cell lines: relationship with the radical scavenger activity.

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20100801

Cucullamide, a new putrescine bisamide from Amoora cucullata.

Chemical & pharmaceutical bulletin 20100801

An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds.

Journal of natural products 20100723

8-Bromo-7-methoxychrysin-induced apoptosis of hepatocellular carcinoma cells involves ROS and JNK.

World journal of gastroenterology 20100721

Chrysin sensitizes tumor necrosis factor-alpha-induced apoptosis in human tumor cells via suppression of nuclear factor-kappaB.

Cancer letters 20100701

Structure-affinity relationship of flavones on binding to serum albumins: effect of hydroxyl groups on ring A.

Molecular nutrition & food research 20100701

Chrysin suppresses IL-6-induced angiogenesis via down-regulation of JAK1/STAT3 and VEGF: an in vitro and in ovo approach.

Journal of agricultural and food chemistry 20100609

Nitrofurantoin transport by placental choriocarcinoma JAr cells: involvement of BCRP, OATP2B1 and other MDR transporters.

Archives of gynecology and obstetrics 20100601

A comparative study of flavonoid analogues on streptozotocin-nicotinamide induced diabetic rats: quercetin as a potential antidiabetic agent acting via 11beta-hydroxysteroid dehydrogenase type 1 inhibition.

European journal of medicinal chemistry 20100601

Dietary bioflavonoids inhibit Escherichia coli ATP synthase in a differential manner.

International journal of biological macromolecules 20100601

Influence of chrysin on hepatic marker enzymes and lipid profile against D-galactosamine-induced hepatotoxicity rats.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100601

Effect of selected flavones on cancer and endothelial cells.

General physiology and biophysics 20100601

Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19).

Bioorganic & medicinal chemistry letters 20100515

Synthesis, characterization and vasculoprotective effects of nitric oxide-donating derivatives of chrysin.

Bioorganic & medicinal chemistry 20100501

Study on the constituents of Mexican propolis and their cytotoxic activity against PANC-1 human pancreatic cancer cells.

Journal of natural products 20100423

Effect of chrysin on hepatoprotective and antioxidant status in D-galactosamine-induced hepatitis in rats.

European journal of pharmacology 20100410

Antigenotoxic studies of different substances to reduce the DNA damage induced by aflatoxin B(1) and ochratoxin A.

Toxins 20100401

Spectrometric study of the interaction between alpinetin and bovine serum albumin using chemometrics approaches.

Analytica chimica acta 20100324

High expression of gabarapl1 is associated with a better outcome for patients with lymph node-positive breast cancer.

British journal of cancer 20100316

Dietary flavonoids activate the constitutive androstane receptor (CAR).

Journal of agricultural and food chemistry 20100224

Flavones suppress type I IL-4 receptor signaling by down-regulating the expression of common gamma chain.

FEBS letters 20100219

Potent inhibitor scaffold against Trypanosoma cruzi trans-sialidase.

Bioorganic & medicinal chemistry 20100215

Apigenin, chrysin, and luteolin selectively inhibit chymotrypsin-like and trypsin-like proteasome catalytic activities in tumor cells.

Planta medica 20100201

Design, synthesis and biological evaluation of chrysin long-chain derivatives as potential anticancer agents.

Bioorganic & medicinal chemistry 20100201

Dietary flavonoids suppress azoxymethane-induced colonic preneoplastic lesions in male C57BL/KsJ-db/db mice.

Chemico-biological interactions 20100127

Antiviral activity and mode of action of propolis extracts and selected compounds.

Phytotherapy research : PTR 20100101

In vitro anti-leukemic activity of the ethno-pharmacological plant Scutellaria orientalis ssp. carica endemic to western Turkey.

Phytomedicine : international journal of phytotherapy and phytopharmacology 20100101

Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.

Bioorganic & medicinal chemistry 20100101

Luteolin triggers global changes in the microglial transcriptome leading to a unique anti-inflammatory and neuroprotective phenotype.

Journal of neuroinflammation 20100101

Protection of burn-induced skin injuries by the flavonoid kaempferol.

BMB reports 20100101

Synthesis and preliminary biological evaluation of chrysin derivatives as potential anticancer drugs.

Medicinal chemistry (Shariqah (United Arab Emirates)) 20100101

Potential effects of chrysin on MDA-MB-231 cells.

International journal of molecular sciences 20100101

Impact of dietary polyphenols on carbohydrate metabolism.

International journal of molecular sciences 20100101

Flavonoids activate pregnane x receptor-mediated CYP3A4 gene expression by inhibiting cyclin-dependent kinases in HepG2 liver carcinoma cells.

BMC biochemistry 20100101

Apoptotic effects of chrysin in human cancer cell lines.

International journal of molecular sciences 20100101

Reversal of multidrug resitance by natural substances from plants.

Current topics in medicinal chemistry 20100101

Differential mechanisms for the inhibition of human cytochrome P450 1A2 by apigenin and genistein.

Journal of biochemical and molecular toxicology 20100101

Structural basis for certain naturally occurring bioflavonoids to function as reducing co-substrates of cyclooxygenase I and II.

PloS one 20100101

Antiproliferative effect of Tualang honey on oral squamous cell carcinoma and osteosarcoma cell lines.

BMC complementary and alternative medicine 20100101

Potent modification of inducible CYP1A1 expression by flavonoids.

Biological & pharmaceutical bulletin 20100101

Medicinal plants used in Northern Peru for reproductive problems and female health.

Journal of ethnobiology and ethnomedicine 20100101

Novel screening method for potential skin-whitening compounds by a luciferase reporter assay.

Bioscience, biotechnology, and biochemistry 20100101

Chungsim-Yeunja-Tang decreases the inflammatory response in peripheral blood mononuclear cells from patients with cerebral infarction through an NF-κB dependent mechanism.

Journal of neuroinflammation 20100101

CYP1A1 and CYP3A4 modulation by dietary flavonoids in human intestinal Caco-2 cells.

Toxicology letters 20091215

Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.

Journal of medicinal chemistry 20091210

Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors.

Bioorganic & medicinal chemistry letters 20091201

7-Hydroxy-benzopyran-4-one derivatives: a novel pharmacophore of peroxisome proliferator-activated receptor alpha and -gamma (PPARalpha and gamma) dual agonists.

Journal of medicinal chemistry 20091112

Methylation of dietary flavones increases their metabolic stability and chemopreventive effects.

International journal of molecular sciences 20091101

CYP1-mediated antiproliferative activity of dietary flavonoids in MDA-MB-468 breast cancer cells.

Toxicology 20091029

Synthesis of C(7) modified chrysin derivatives designing to inhibit beta-ketoacyl-acyl carrier protein synthase III (FabH) as antibiotics.

Bioorganic & medicinal chemistry 20090901

Effect of flavonoids on androgen and glucocorticoid receptors based on in vitro reporter gene assay.

Bioorganic & medicinal chemistry letters 20090815

Evaluation of radioprotective effects of propolis and its flavonoid constituents: in vitro study on human white blood cells.

Phytotherapy research : PTR 20090801

Cytotoxicity of flavones and flavonols to a human esophageal squamous cell carcinoma cell line (KYSE-510) by induction of G2/M arrest and apoptosis.

Toxicology in vitro : an international journal published in association with BIBRA 20090801

In vitro kinetic properties of the Thr201Met variant of human aromatase gene CYP19A1: functional responses to substrate and product inhibition and enzyme inhibitors.

The Journal of clinical endocrinology and metabolism 20090801

Inhibitory effects of flavonoids isolated from Fragaria ananassa Duch on IgE-mediated degranulation in rat basophilic leukemia RBL-2H3.

Bioorganic & medicinal chemistry 20090801

[Synthesis of biflavones and their interaction with DNA].

Yao xue xue bao = Acta pharmaceutica Sinica 20090801

Development and validation of a high-performance liquid chromatographic method for determination of pinocembrin in rat plasma: application to pharmacokinetic study.

Journal of pharmaceutical and biomedical analysis 20090712

Antifeedant activity of ethanolic extract from Flourensia oolepis and isolation of pinocembrin as its active principle compound.

Bioresource technology 20090701

Antiinflammatory and antinociceptive activities of gossypin and procumbentin--cyclooxygenase-2 (COX-2) inhibition studies.

Phytotherapy research : PTR 20090601

Breast cancer resistance protein interacts with various compounds in vitro, but plays a minor role in substrate efflux at the blood-brain barrier.

Drug metabolism and disposition: the biological fate of chemicals 20090601

Hepatoprotective effect of chrysin on prooxidant-antioxidant status during ethanol-induced toxicity in female albino rats.

The Journal of pharmacy and pharmacology 20090601

Scuteflorins A and B, dihydropyranocoumarins from Scutellaria lateriflora.

Journal of natural products 20090601

Simultaneous quantification of eight major bioactive phenolic compounds in Chinese propolis by high-performance liquid chromatography.

Natural product communications 20090601

Inhibitory effects of flavonoids on TNF-alpha-induced IL-8 gene expression in HEK 293 cells.

BMB reports 20090531

Correlation between antiangiogenic activity and antioxidant activity of various components from propolis.

Molecular nutrition & food research 20090501

Simultaneous determination of 11 active components in two well-known traditional Chinese medicines by HPLC coupled with diode array detection for quality control.

Journal of pharmaceutical and biomedical analysis 20090501

Chrysin, a natural flavone, improves murine inflammatory bowel diseases.

Biochemical and biophysical research communications 20090417

Suppression of the TRIF-dependent signaling pathway of Toll-like receptors by luteolin.

Biochemical pharmacology 20090415

Main flavonoids, DPPH activity, and metal content allow determination of the geographical origin of propolis from the Province of San Juan (Argentina).

Journal of agricultural and food chemistry 20090408

Cytotoxic constituents of chinese propolis.

Journal of natural products 20090401

Food flavonoid aryl hydrocarbon receptor-mediated agonistic/antagonistic/synergic activities in human and rat reporter gene assays.

Analytica chimica acta 20090401

Comparison of intraperitoneal honey and sodium hyaluronate-carboxymethylcellulose (Seprafilm) for the prevention of postoperative intra-abdominal adhesions.

Clinics (Sao Paulo, Brazil) 20090401

Trihydroxynaphthalene reductase of Curvularia lunata--a target for flavonoid action?

Chemico-biological interactions 20090316

Mechanism of CYP2C9 inhibition by flavones and flavonols.

Drug metabolism and disposition: the biological fate of chemicals 20090301

Antioxidant effects of flavonoid from Croatian Cystus incanus L. rich bee pollen.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090301

Quantum-SAR extension of the spectral-SAR algorithm: application to polyphenolic anticancer bioactivity.

International journal of molecular sciences 20090301

5,7-Dimeth-oxy-2-phenyl-4H-chromen-4-one.

Acta crystallographica. Section E, Structure reports online 20090301

6,8-Dibromo-5-hydr-oxy-4-oxo-2-phenyl-4H-chromen-7-yl acetate.

Acta crystallographica. Section E, Structure reports online 20090301

2-Bromo-5,7-dimeth-oxy-4-phenyl-quinoline.

Acta crystallographica. Section E, Structure reports online 20090301

Synthesis and promotion angiogenesis effect of chrysin derivatives coupled to NO donors.

Bioorganic & medicinal chemistry letters 20090215

Multiple compounds determination and fingerprint analysis of Lidanpaishi tablet and keli by high-performance liquid chromatography.

Analytica chimica acta 20090202

MS/MS spectral tag-based annotation of non-targeted profile of plant secondary metabolites.

The Plant journal : for cell and molecular biology 20090201

Dimethyl 2,2'-[(4-oxo-2-phenyl-4H-chromene-5,7-diyl)dioxy]diacetate: a more densely packed polymorph.

Acta crystallographica. Section E, Structure reports online 20090201

Discovery of a potent and selective inhibitor for human carbonyl reductase 1 from propionate scanning applied to the macrolide zearalenone.

Bioorganic & medicinal chemistry 20090115

In vitro antitumor mechanisms of various Scutellaria extracts and constituent flavonoids.

Planta medica 20090101

Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases.

BMC medical genomics 20090101

Bear bile: dilemma of traditional medicinal use and animal protection.

Journal of ethnobiology and ethnomedicine 20090101

Structure-activity relationship of 7 flavonoids on recombinant human protein kinase CK2 holoenzyme.

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20090101

Simple and reliable methods for the determination of sixteen marker components for quality control of Daochi pill by HPLC coupled with diode array detection.

Phytochemical analysis : PCA 20090101

From functional food to medicinal product: systematic approach in analysis of polyphenolics from propolis and wine.

Nutrition journal 20090101

Antiproliferative effects of honey and of its polyphenols: a review.

Journal of biomedicine & biotechnology 20090101

Differential effects of chrysin on nitrofurantoin pharmacokinetics mediated by intestinal breast cancer resistance protein in rats and mice.

Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20090101

Synthesis, cytotoxic activity, and DNA binding properties of copper (II) complexes with hesperetin, naringenin, and apigenin.

Bioinorganic chemistry and applications 20090101

Bee products prevent VEGF-induced angiogenesis in human umbilical vein endothelial cells.

BMC complementary and alternative medicine 20090101

Cofactor-activated phosphorylation is required for inhibition of cortical neuron differentiation by Groucho/TLE1.

PloS one 20090101

Prevention of selenite-induced cataractogenesis by rutin in Wistar rats.

Molecular vision 20090101

[Comparative effects of flavonoids on cell cycle passage and apoptosis induction in human acute lymphoblastic leukemia MT-4 cells].

Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20090101

2-Phenyl-5,7-bis-(prop-2-en-1-yl-oxy)-4H-chromen-4-one.

Acta crystallographica. Section E, Structure reports online 20090101

Analysis of flavonoids in propolis and Ginkgo biloba by micellar electrokinetic capillary chromatography.

Journal of agricultural and food chemistry 20081224

Flow-injection chemiluminescence determination of chrysin and baicalein assisted by theoretical prediction of chemiluminescence behavior of chrysin and baicalein.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081201

Antioxidant and antimicrobial effects of phenolic compounds extracts of Northeast Portugal honey.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081201

Negative ion 'chip-based' nanospray tandem mass spectrometry for the analysis of flavonoids in glandular trichomes of Lychnophora ericoides Mart. (Asteraceae).

Rapid communications in mass spectrometry : RCM 20081201

[Cytotoxicity of polyphenolic/flavonoid compounds in a leukaemia cell culture].

Arhiv za higijenu rada i toksikologiju 20081201

Authors' correction: chrysin is a Passiflora coerulea extract.

AANA journal 20081201

Hexaaqua-(5,7-dihydr-oxy-4-oxo-2-phenyl-4H-chromene-8-sulfonato)calcium(II) 5,7-dihydr-oxy-4-oxo-2-phenyl-4H-chromene-8-sulfonate trihydrate.

Acta crystallographica. Section E, Structure reports online 20081201

5,7-Bis(benz-yloxy)-2-phenyl-4H-chromen-4-one.

Acta crystallographica. Section E, Structure reports online 20081201

Structural requirements for the flavonoid fisetin in inhibiting fibril formation of amyloid beta protein.

Neuroscience letters 20081031

Protective effects of Chinese propolis and its component, chrysin, against neuronal cell death via inhibition of mitochondrial apoptosis pathway in SH-SY5Y cells.

Journal of agricultural and food chemistry 20081008

Testosterone and dihydrotestosterone inhibit gallbladder motility through multiple signalling pathways.

Steroids 20081001

Relationship between the methylation status of dietary flavonoids and their growth-inhibitory and apoptosis-inducing activities in human cancer cells.

Journal of cellular biochemistry 20081001

Modulation of signalling nuclear factor-kappaB activation pathway by polyphenols in human intestinal Caco-2 cells.

The British journal of nutrition 20080901

A p38-p65 transcription complex induced by endothelin-1 mediates signal transduction in cancer cells.

Biochimica et biophysica acta 20080901

Enhanced detection and structural characterization of flavonoids by complexation with N,O-bis(trimethysilyl)trifluoroacetamide using electrospray ionization mass spectrometry.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20080901

Chemical composition and botanical origin of red propolis, a new type of brazilian propolis.

Evidence-based complementary and alternative medicine : eCAM 20080901

[Studies on ethyl acetate soluble constituents of Huanglian Jiedutang].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080901

Effect of flavonoids on rat splenocytes, a structure-activity relationship study.

Biochemical pharmacology 20080815

QSAR modeling of the interaction of flavonoids with GABA(A) receptor.

European journal of medicinal chemistry 20080801

Modulation of glucose uptake in a human choriocarcinoma cell line (BeWo) by dietary bioactive compounds and drugs of abuse.

Journal of biochemistry 20080801

Chrysin induces hyperalgesia via the GABAA receptor in mice.

Planta medica 20080801

Protein engineering on biphenyl dioxygenase for conferring activity to convert 7-hydroxyflavone and 5,7-dihydroxyflavone (chrysin).

Journal of bioscience and bioengineering 20080801

Discovery of nonsteroidal 17beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries.

Journal of medicinal chemistry 20080724

Galangin increases the cytotoxic activity of imatinib mesylate in imatinib-sensitive and imatinib-resistant Bcr-Abl expressing leukemia cells.

Cancer letters 20080708

Multi-substrate flavonol O-glucosyltransferases from strawberry (Fragaria x ananassa) achene and receptacle.

Journal of experimental botany 20080701

[Linear scale-up of the separation of active components from Oroxylum indicum using high-speed counter-current chromatography].

Se pu = Chinese journal of chromatography 20080701

Role of Bax in quercetin-induced apoptosis in human prostate cancer cells.

Biochemical pharmacology 20080615

Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

Journal of medicinal chemistry 20080612

Flavones and flavonols exert cytotoxic effects on a human oesophageal adenocarcinoma cell line (OE33) by causing G2/M arrest and inducing apoptosis.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080601

Investigations on the fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene by certain flavonoids.

Journal of photochemistry and photobiology. B, Biology 20080529

Assessment of luteolin (3',4',5,7-tetrahydroxyflavone) neuropharmacological activity.

Behavioural brain research 20080516

Quercetin decreases intracellular GSH content and potentiates the apoptotic action of the antileukemic drug arsenic trioxide in human leukemia cell lines.

Biochemical pharmacology 20080515

Aromatase inhibition by synthetic lactones and flavonoids in human placental microsomes and breast fibroblasts--a comparative study.

Toxicology and applied pharmacology 20080501

Chrysin, a natural flavonoid enhances steroidogenesis and steroidogenic acute regulatory protein gene expression in mouse Leydig cells.

The Journal of endocrinology 20080501

Flavonoids-induced accumulation of hypoxia-inducible factor (HIF)-1alpha/2alpha is mediated through chelation of iron.

Journal of cellular biochemistry 20080415

Signal molecules in the peanut-bradyrhizobia interaction.

Archives of microbiology 20080401

Microbial metabolism part 9. Structure and antioxidant significance of the metabolites of 5,7-dihydroxyflavone (chrysin), and 5- and 6-hydroxyflavones.

Chemical & pharmaceutical bulletin 20080401

Phytoestrogens and breast cancer prevention: possible mechanisms of action.

Environmental health perspectives 20080401

The effects of chrysin, a Passiflora incarnata extract, on natural killer cell activity in male Sprague-Dawley rats undergoing abdominal surgery.

AANA journal 20080401

Flavonoids diosmetin and luteolin inhibit midazolam metabolism by human liver microsomes and recombinant CYP 3A4 and CYP3A5 enzymes.

Biochemical pharmacology 20080315

Pharmacological studies on hypotensive, diuretic and vasodilator activities of chrysin glucoside from Calycotome villosa in rats.

Phytotherapy research : PTR 20080301

Synthesis and biological evaluation of novel 8-aminomethylated oroxylin A analogues as alpha-glucosidase inhibitors.

Bioorganic & medicinal chemistry letters 20080301

Effects of Food Natural Products on the Biotransformation of PCBs.

Environmental toxicology and pharmacology 20080301

Complexation of flavonoids with iron: structure and optical signatures.

The journal of physical chemistry. B 20080214

Cytotoxic effects of the dietary flavones chrysin and apigenin in a normal trout liver cell line.

Chemico-biological interactions 20080110

Behavioral effects of 6-bromoflavanone and 5-methoxy-6,8-dibromoflavanone as anxiolytic compounds.

Progress in neuro-psychopharmacology & biological psychiatry 20080101

Evaluation of the radioprotective effects of propolis and flavonoids in gamma-irradiated mice: the alkaline comet assay study.

Biological & pharmaceutical bulletin 20080101

Reversal of multidrug resistance by synthetic and natural compounds in drug-resistant MCF-7 cell lines.

Chemotherapy 20080101

Activated PPARgamma Targets Surface and Intracellular Signals That Inhibit the Proliferation of Lung Carcinoma Cells.

PPAR research 20080101

Common dietary flavonoids inhibit the growth of the intraerythrocytic malaria parasite.

BMC research notes 20080101

Jaceosidin induces apoptosis in human ovary cancer cells through mitochondrial pathway.

Journal of biomedicine & biotechnology 20080101

PPARgamma: The Portrait of a Target Ally to Cancer Chemopreventive Agents.

PPAR research 20080101

Synthesis and enantiomeric resolution of (+/-)-pinocembrin.

Journal of Asian natural products research 20080101

Inflammaging as a prodrome to Alzheimer's disease.

Journal of neuroinflammation 20080101

Lipopolysaccharide (LPS) potentiates hydrogen peroxide toxicity in T98G astrocytoma cells by suppression of anti-oxidative and growth factor gene expression.

BMC genomics 20080101

Influence of some bioflavonoids on the transport of nitrendipine.

Drug metabolism and drug interactions 20080101

Plasma, tissue and urinary levels of aloin in rats after the administration of pure aloin.

Nutrition research and practice 20080101

[Effects of flavonoids with different structures on proliferation of leukemia cell line HL-60].

Ai zheng = Aizheng = Chinese journal of cancer 20071201

Iron-binding properties of plant phenolics and cranberry's bio-effects.

Dalton transactions (Cambridge, England : 2003) 20071121

Enzymatic acylation of flavonoids: effect of the nature of the substrate, origin of lipase, and operating conditions on conversion yield and regioselectivity.

Journal of agricultural and food chemistry 20071114

Analysis of the polyphenolic fraction of propolis from different sources by liquid chromatography-tandem mass spectrometry.

Journal of pharmaceutical and biomedical analysis 20071105

Sonoran propolis: chemical composition and antiproliferative activity on cancer cell lines.

Planta medica 20071101

Effect of 7-O-beta-D-glucopyranosylchrysin and its aglycone chrysin isolated from Podocytisus caramanicus on estrogen receptor alpha transcriptional activity.

Planta medica 20071101

Dietary flavonoid apigenin is a potential inducer of intracellular oxidative stress: the role in the interruptive apoptotic signal.

Archives of biochemistry and biophysics 20071015

Flavonoids induce germination of basidiospores of the ectomycorrhizal fungus Suillus bovinus.

Mycorrhiza 20071001

Comparative molecular field analysis of flavonoid inhibitors of the PIM-1 kinase.

Bioorganic & medicinal chemistry 20071001

Determination of flavonoid aglycones in several food samples by mixed micellar electrokinetic chromatography.

Journal of separation science 20071001

Evaluation of the anxiolytic effects of chrysin, a Passiflora incarnata extract, in the laboratory rat.

AANA journal 20071001

2-Styrylchromones: novel strong scavengers of reactive oxygen and nitrogen species.

Bioorganic & medicinal chemistry 20070915

Dietary flavones suppresses IgE and Th2 cytokines in OVA-immunized BALB/c mice.

European journal of nutrition 20070801

Wogonin but not Nor-wogonin inhibits lipopolysaccharide and lipoteichoic acid-induced iNOS gene expression and NO production in macrophages.

International immunopharmacology 20070801

Induction of apoptosis of human gastric carcinoma SGC-7901 cell line by 5, 7-dihydroxy-8-nitrochrysin in vitro.

World journal of gastroenterology 20070728

Chrysin inhibited stem cell factor (SCF)/c-Kit complex-induced cell proliferation in human myeloid leukemia cells.

Biochemical pharmacology 20070715

Computational studies of the binding mechanism of calmodulin with chrysin.

Biochemical and biophysical research communications 20070713

Selected flavonoids potentiate the toxicity of cisplatin in human lung adenocarcinoma cells: a role for glutathione depletion.

International journal of oncology 20070701

Effect of chrysin and natural coumarins on UGT1A1 and 1A6 activities in rat and human hepatocytes in primary culture.

Planta medica 20070701

(Anti)estrogenic effects of phytochemicals on human primary mammary fibroblasts, MCF-7 cells and their co-culture.

Toxicology and applied pharmacology 20070615

Interaction of flavonoids with red blood cell membrane lipids and proteins: antioxidant and antihemolytic effects.

International journal of biological macromolecules 20070601

The effect of flavones and flavonols on colonization of tomato plants by arbuscular mycorrhizal fungi of the genera Gigaspora and Glomus.

Canadian journal of microbiology 20070601

Cancer chemopreventive properties of orally bioavailable flavonoids--methylated versus unmethylated flavones.

Biochemical pharmacology 20070501

Reversal of inflammation-associated dihydrodiol dehydrogenases (AKR1C1 and AKR1C2) overexpression and drug resistance in nonsmall cell lung cancer cells by wogonin and chrysin.

International journal of cancer 20070501

Variable sulfation of dietary polyphenols by recombinant human sulfotransferase (SULT) 1A1 genetic variants and SULT1E1.

Drug metabolism and disposition: the biological fate of chemicals 20070501

An antifungal compound involved in symbiotic germination of Cypripedium macranthos var. rebunense (Orchidaceae).

Phytochemistry 20070501

Assessment by survival analysis of the radioprotective properties of propolis and its polyphenolic compounds.

Biological & pharmaceutical bulletin 20070501

[Synthesis of chrysin derivatives and their interaction with DNA].

Yao xue xue bao = Acta pharmaceutica Sinica 20070501

Phytochemicals induce breast cancer resistance protein in Caco-2 cells and enhance the transport of benzo[a]pyrene-3-sulfate.

Toxicological sciences : an official journal of the Society of Toxicology 20070401

Rational design of novel, potent small molecule pan-selectin antagonists.

Journal of medicinal chemistry 20070322

Identification of kaempferol as an inhibitor of cigarette smoke-induced activation of the aryl hydrocarbon receptor and cell transformation.

Carcinogenesis 20070301

Structure activity relationship of antioxidative property of flavonoids and inhibitory effect on matrix metalloproteinase activity in UVA-irradiated human dermal fibroblast.

Archives of pharmacal research 20070301

Antioxidant compounds of propolis determined by capillary electrophoresis-mass spectrometry.

Journal of separation science 20070301

Effects of the flavonoid chrysin on nitrofurantoin pharmacokinetics in rats: potential involvement of ABCG2.

Drug metabolism and disposition: the biological fate of chemicals 20070201

Flavonoids modulate monocarboxylate transporter-1-mediated transport of gamma-hydroxybutyrate in vitro and in vivo.

Drug metabolism and disposition: the biological fate of chemicals 20070201

The role of chrysin and the ah receptor in induction of the human UGT1A1 gene in vitro and in transgenic UGT1 mice.

Hepatology (Baltimore, Md.) 20070201

Structure-proteasome-inhibitory activity relationships of dietary flavonoids in human cancer cells.

Frontiers in bioscience : a journal and virtual library 20070101

Chrysin inhibits expression of hypoxia-inducible factor-1alpha through reducing hypoxia-inducible factor-1alpha stability and inhibiting its protein synthesis.

Molecular cancer therapeutics 20070101

In vitro antimicrobial activity of propolis samples from different geographical origins against certain oral pathogens.

Anaerobe 20070101

[Studies on chemical components of Cirsium segestum].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070101

[The estimation of biological value and quality of propolis and propolis based food products and food dietary supplements].

Voprosy pitaniia 20070101

The flavonoid luteolin worsens chemical-induced colitis in NF-kappaB(EGFP) transgenic mice through blockade of NF-kappaB-dependent protective molecules.

PloS one 20070101

Evaluation of propolis polyphenols absorption in humans by liquid chromatography/tandem mass spectrometry.

Rapid communications in mass spectrometry : RCM 20070101

Peroxisome proliferator-activated receptors in lung cancer.

PPAR research 20070101

Estrogenic activity of the chlorinated derivatives of estrogens and flavonoids using a GFP expression system.

Environmental toxicology and pharmacology 20070101

Dietary flavonoids attenuate tumor necrosis factor alpha-induced adhesion molecule expression in human aortic endothelial cells. Structure-function relationships and activity after first pass metabolism.

The Journal of biological chemistry 20061201

Accumulation and metabolism of the anticancer flavonoid 5,7-dimethoxyflavone compared to its unmethylated analog chrysin in the Atlantic killifish.

Chemico-biological interactions 20061201

Toxicological aspects of flavonoid interaction with biomacromolecules.

Neuro endocrinology letters 20061201

Quercetin, a flavonoid, inhibits proliferation and increases osteogenic differentiation in human adipose stromal cells.

Biochemical pharmacology 20061115

Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.

Journal of molecular graphics & modelling 20061101

Oxidant/antioxidant properties of Croatian native propolis.

Journal of agricultural and food chemistry 20061018

Inhibition of pro-inflammatory markers in primary bone marrow-derived mouse macrophages by naturally occurring flavonoids: analysis of the structure-activity relationship.

Biochemical pharmacology 20061016

Gateways to clinical trials.

Methods and findings in experimental and clinical pharmacology 20061001

Analysis of flavonoids from propolis by on-line HPLC-electrospray mass spectrometry.

Journal of pharmaceutical and biomedical analysis 20060926

Aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha in MCF-7 breast cancer cells.

Biological chemistry 20060901

Modulation of activator protein-1 (AP-1) and MAPK pathway by flavonoids in human prostate cancer PC3 cells.

Archives of pharmacal research 20060801

Retention behavior of silica-bonded and novel polymeric reversed-phase sorbents in studies on flavones as chemotaxonomic markers of Scutellaria L. genus.

Journal of chromatography. A 20060707

Flavonoid-induced glutathione depletion: potential implications for cancer treatment.

Free radical biology & medicine 20060701

Combinatorial biosynthesis of flavones and flavonols in Escherichia coli.

Applied microbiology and biotechnology 20060601

Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids.

Journal of medicinal chemistry 20060601

Chrysin inhibits lipopolysaccharide-induced angiogenesis via down-regulation of VEGF/VEGFR-2(KDR) and IL-6/IL-6R pathways.

Planta medica 20060601

Modulation of aromatase activity by diet polyphenolic compounds.

Journal of agricultural and food chemistry 20060517

Antitumor activity of some natural flavonoids and synthetic derivatives on various human and murine cancer cell lines.

Bioorganic & medicinal chemistry 20060501

Preventive effects of chrysin on the development of azoxymethane-induced colonic aberrant crypt foci in rats.

Oncology reports 20060501

Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Dietary flavonoids: effects on xenobiotic and carcinogen metabolism.

Toxicology in vitro : an international journal published in association with BIBRA 20060301

Cyanobacterial chemotaxis to extracts of host and nonhost plants.

FEMS microbiology ecology 20060301

Effect of different flavonoids on collagen synthesis in human fibroblasts.

Plant foods for human nutrition (Dordrecht, Netherlands) 20060301

A pilot study on the safety of combining chrysin, a non-absorbable inducer of UGT1A1, and irinotecan (CPT-11) to treat metastatic colorectal cancer.

Cancer chemotherapy and pharmacology 20060201

Synthesis and biological evaluation of novel C (7) modified chrysin analogues as antibacterial agents.

Bioorganic & medicinal chemistry letters 20060101

Use of the pig caecum model to mimic the human intestinal metabolism of hispidulin and related compounds.

Molecular nutrition & food research 20060101

Biosynthesis of isoprenoids, polyunsaturated fatty acids and flavonoids in Saccharomyces cerevisiae.

Microbial cell factories 20060101

Differential UGT1A1 induction by chrysin in primary human hepatocytes and HepG2 Cells.

The Journal of pharmacology and experimental therapeutics 20051201

Bcl-2 attenuates anticancer agents-induced apoptosis by sustained activation of Akt/protein kinase B in U937 cells.

Apoptosis : an international journal on programmed cell death 20051201

Biflavonoids from Lonicera japonica.

Phytochemistry 20051201

Structural basis of inhibitor specificity of the human protooncogene proviral insertion site in moloney murine leukemia virus (PIM-1) kinase.

Journal of medicinal chemistry 20051201

Determination of the overlapping pK(a) values of chrysin using UV-vis spectroscopy and ab initio methods.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20051101

Antiherpetic activities of flavonoids against herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) in vitro.

Archives of pharmacal research 20051101

Water-soluble derivative of propolis and its polyphenolic compounds enhance tumoricidal activity of macrophages.

Journal of ethnopharmacology 20051031

Molecular targets of dietary polyphenols with anti-inflammatory properties.

Yonsei medical journal 20051031

Differential modulation of ochratoxin A absorption across Caco-2 cells by dietary polyphenols, used at realistic intestinal concentrations.

Toxicology letters 20051015

Effects of hydroxyl group numbers on the B-ring of 5,7-dihydroxyflavones on the differential inhibition of human CYP 1A and CYP1B1 enzymes.

Archives of pharmacal research 20051001

Phytoestrogens as inhibitors of fungal 17beta-hydroxysteroid dehydrogenase.

Steroids 20050901

Synthesis and inhibition of PGE2 production of 6,8-disubstituted chrysin derivatives.

European journal of medicinal chemistry 20050901

Endothelial nitric oxide production stimulated by the bioflavonoid chrysin in rat isolated aorta.

Planta medica 20050901

Phytoestrogens as inhibitors of fungal 17beta-hydroxysteroid dehydrogenase.

Steroids 20050801

Structure and antiinflammatory activity relationships of wogonin derivatives.

Archives of pharmacal research 20050801

Human NAD(P)H:quinone oxidoreductase inhibition by flavonoids in living cells.

Free radical biology & medicine 20050715

Flavonoids exhibit fungal species and genus specific effects on the presymbiotic growth of Gigaspora and Glomus.

Mycological research 20050701

Chrysin induces G1 phase cell cycle arrest in C6 glioma cells through inducing p21Waf1/Cip1 expression: involvement of p38 mitogen-activated protein kinase.

Biochemical pharmacology 20050615

Biotransformation of chrysin and apigenin by Cunninghamella elegans.

Chemical & pharmaceutical bulletin 20050601

Synthesis and iNOS inhibitory activities of thioflavones.

Archives of pharmacal research 20050601

Human gut microbial degradation of flavonoids: structure-function relationships.

Journal of agricultural and food chemistry 20050518

Production of cytokine and NO by RAW 264.7 macrophages and PBMC in vitro incubation with flavonoids.

Archives of pharmacal research 20050501

Effects of flavonoids on cell proliferation and caspase activation in a human colonic cell line HT29: an SAR study.

Journal of medicinal chemistry 20050421

Stability of ferric complexes with 3-hydroxyflavone (flavonol), 5,7-dihydroxyflavone (chrysin), and 3',4'-dihydroxyflavone.

Journal of agricultural and food chemistry 20050420

A sensitive method for determination of COL-3, a chemically modified tetracycline, in human plasma using high-performance liquid chromatography and ultraviolet detection.

Journal of pharmaceutical and biomedical analysis 20050401

Synergistic antitumor effect of polyphenolic components of water soluble derivative of propolis against Ehrlich ascites tumour.

Biological & pharmaceutical bulletin 20050401

[Isolation and structure identification of chemical constituents from Viscum liquidambaricolum].

Yao xue xue bao = Acta pharmaceutica Sinica 20050401

Flavonoids from the leaves of Litsea japonica and their anti-complement activity.

Phytotherapy research : PTR 20050401

Expression profiling of the estrogen responsive genes in response to phytoestrogens using a customized DNA microarray.

FEBS letters 20050314

Kinetic study of the quenching reaction of singlet oxygen by flavonoids in ethanol solution.

The journal of physical chemistry. B 20050310

Flavones suppress the expression of the high-affinity IgE receptor FcepsilonRI in human basophilic KU812 cells.

Journal of agricultural and food chemistry 20050309

Flavonoids chrysin and benzoflavone, potent breast cancer resistance protein inhibitors, have no significant effect on topotecan pharmacokinetics in rats or mdr1a/1b (-/-) mice.

Drug metabolism and disposition: the biological fate of chemicals 20050301

Cell-based high-throughput bioassays to assess induction and inhibition of CYP1A enzymes.

Toxicology in vitro : an international journal published in association with BIBRA 20050301

[Xanthine oxidase inhibitory activity and hypouricemia effect of propolis in rats].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20050301

Crystal structure of a human cyclin-dependent kinase 6 complex with a flavonol inhibitor, fisetin.

Journal of medicinal chemistry 20050210

[Studies on chemical constituents from Elsholtzia bodinieri Vaniot].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20050201

Chrysin suppresses lipopolysaccharide-induced cyclooxygenase-2 expression through the inhibition of nuclear factor for IL-6 (NF-IL6) DNA-binding activity.

FEBS letters 20050131

Comparison of high-speed counter-current chromatography instruments for the separation of the extracts of the seeds of Oroxylum indicum.

Journal of chromatography. A 20050121

Decreased pro-inflammatory cytokine production by LPS-stimulated PBMC upon in vitro incubation with the flavonoids apigenin, luteolin or chrysin, due to selective elimination of monocytes/macrophages.

Biochemical pharmacology 20050115

Dietary polyphenols protect dopamine neurons from oxidative insults and apoptosis: investigations in primary rat mesencephalic cultures.

Biochemical pharmacology 20050115

Analysis of substrate specificities and tissue expression of rat UDP-glucuronosyltransferases UGT1A7 and UGT1A8.

Drug metabolism and disposition: the biological fate of chemicals 20050101

Baicalein protects rat cardiomyocytes from hypoxia/reoxygenation damage via a prooxidant mechanism.

Cardiovascular research 20050101

In vitro digestion and lactase treatment influence uptake of quercetin and quercetin glucoside by the Caco-2 cell monolayer.

Nutrition journal 20050101

Determination of six kavalactones in dietary supplements and selected functional foods containing Piper methysticum by isocratic liquid chromatography with internal standard.

Journal of AOAC International 20050101

Comparative effects of fibrates on drug metabolizing enzymes in human hepatocytes.

Pharmaceutical research 20050101

In vitro search for synergy between flavonoids and epirubicin on multidrug-resistant cancer cells.

In vivo (Athens, Greece) 20050101

Chemical compositions and antimicrobial activities of four different Anatolian propolis samples.

Microbiological research 20050101

The effects of dietary phytoestrogens on aromatase activity in human endometrial stromal cells.

Reproduction, nutrition, development 20050101

Chrysin-induced apoptosis is mediated through caspase activation and Akt inactivation in U937 leukemia cells.

Biochemical and biophysical research communications 20041224

Evaluation of the first-pass glucuronidation of selected flavones in gut by Caco-2 monolayer model.

Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20041220

A photoaffinity probe designed for host-specific signal flavonoid receptors in phytopathogenic Peronosporomycete zoospores of Aphanomyces cochlioides.

Archives of biochemistry and biophysics 20041215

Chrysin and its phosphate ester inhibit cell proliferation and induce apoptosis in Hela cells.

Bioorganic & medicinal chemistry 20041201

Induction and inhibition of aromatase (CYP19) activity by natural and synthetic flavonoid compounds in H295R human adrenocortical carcinoma cells.

Toxicological sciences : an official journal of the Society of Toxicology 20041101

A UV resonance Raman (UVRR) spectroscopic study on the extractable compounds in Scots pine (Pinus sylvestris) wood. Part II. Hydrophilic compounds.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20041101

Vascular and anti-oxidant actions of flavonols and flavones.

Clinical and experimental pharmacology & physiology 20041101

Phytochemicals inhibit catechol-O-methyltransferase activity in cytosolic fractions from healthy human mammary tissues: implications for catechol estrogen-induced DNA damage.

Toxicological sciences : an official journal of the Society of Toxicology 20041001

Vasorelaxing effects of flavonoids: investigation on the possible involvement of potassium channels.

Naunyn-Schmiedeberg's archives of pharmacology 20041001

Dietary polyphenols (-)-epicatechin and chrysin inhibit intestinal glucuronidation metabolism to increase drug absorption.

Journal of pharmaceutical sciences 20040901

Flavonoids inhibit tumor necrosis factor-alpha-induced up-regulation of intercellular adhesion molecule-1 (ICAM-1) in respiratory epithelial cells through activator protein-1 and nuclear factor-kappaB: structure-activity relationships.

Molecular pharmacology 20040901

Inhibitory effect of flavonoids on N-acetylation of 5-aminosalicylic acid in cultured rat hepatocytes.

Biological & pharmaceutical bulletin 20040901

The pig caecum model: a suitable tool to study the intestinal metabolism of flavonoids.

Molecular nutrition & food research 20040901

Synthesis and biological evaluation of flavonoids as vasorelaxant agents.

Bioorganic & medicinal chemistry letters 20040802

Structural and spectroscopic study of 5,7-dihydroxy-flavone and its complex with aluminum.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040801

Electrospray ionization mass spectrometry fingerprinting of propolis.

The Analyst 20040801

Synthesis and aromatase inhibitory activity of novel pyridine-containing isoflavones.

Journal of medicinal chemistry 20040729

Effect of flavonoids and vitamin E on cyclooxygenase-2 (COX-2) transcription.

Mutation research 20040713

Combined effects of multiple flavonoids on breast cancer resistance protein (ABCG2)-mediated transport.

Pharmaceutical research 20040701

Phytoestrogens/flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance.

Cancer research 20040615

Determination of SU5416, a novel angiogenesis inhibitor, in human plasma by liquid chromatography.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040605

Separation of flavonoids and phenolic acids from propolis by capillary zone electrophoresis.

Electrophoresis 20040601

Investigation of the membrane localization and distribution of flavonoids by high-resolution magic angle spinning NMR spectroscopy.

Biochimica et biophysica acta 20040527

Identification of metabolites in plasma and urine of Uruguayan propolis-treated rats.

Journal of agricultural and food chemistry 20040519

Neuroprotective effects of flavones on hydrogen peroxide-induced apoptosis in SH-SY5Y neuroblostoma cells.

Bioorganic & medicinal chemistry letters 20040503

Flavonoids are inhibitors of breast cancer resistance protein (ABCG2)-mediated transport.

Molecular pharmacology 20040501

Inhibitory effect of flavonoids on sulfo- and glucurono-conjugation of acetaminophen in rat cultured hepatocytes and liver subcellular preparations.

Biological & pharmaceutical bulletin 20040501

Antioxidative bioavailability of artepillin C in Brazilian propolis.

Archives of biochemistry and biophysics 20040415

Synthesis and inhibitory activity against COX-2 catalyzed prostaglandin production of chrysin derivatives.

Bioorganic & medicinal chemistry letters 20040308

Effects of ethanol extract of propolis (EEP) and its flavones on inducible gene expression in J774A.1 macrophages.

Journal of ethnopharmacology 20040301

Synthesis and biological activities of 8-arylflavones.

Archives of pharmacal research 20040301

The induction of human UDP-glucuronosyltransferase 1A1 mediated through a distal enhancer module by flavonoids and xenobiotics.

Biochemical pharmacology 20040301

Quantitative high-performance liquid chromatography analyses of flavonoids in Australian Eucalyptus honeys.

Journal of agricultural and food chemistry 20040128

Differential and special properties of the major human UGT1-encoded gastrointestinal UDP-glucuronosyltransferases enhance potential to control chemical uptake.

The Journal of biological chemistry 20040109

Antiproliferative activity of various flavonoids and related compounds: additive effect of interferon-alpha2b.

Bioorganic & medicinal chemistry letters 20040105

Modulation of the activity of pro-inflammatory enzymes, COX-2 and iNOS, by chrysin derivatives.

Pharmacological research 20040101

Antioxidant capacity of reaction products limits the applicability of the Trolox Equivalent Antioxidant Capacity (TEAC) assay.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040101

The nature of phosphorylated chrysin-protein interactions involved in noncovalent complex formation by electrospray ionization mass spectroscopy.

Analytical chemistry 20040101

A hydroxyl group of flavonoids affects oral anti-inflammatory activity and inhibition of systemic tumor necrosis factor-alpha production.

Bioscience, biotechnology, and biochemistry 20040101

Individual and interactive effects of apigenin analogs on G2/M cell-cycle arrest in human colon carcinoma cell lines.

Nutrition and cancer 20040101

Effects of the dietary flavonoid chrysin in isolated rat mesenteric vascular bed.

Journal of vascular research 20040101

Flavonoids induce apoptosis in human leukemia U937 cells through caspase- and caspase-calpain-dependent pathways.

Nutrition and cancer 20040101

Constituents of Quinchamalium majus with potential antitubercular activity.

Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101

Effects of flavonoids on vascular smooth muscle of the isolated rat thoracic aorta.

Life sciences 20031219

P53 hot-spot mutants are resistant to ubiquitin-independent degradation by increased binding to NAD(P)H:quinone oxidoreductase 1.

Proceedings of the National Academy of Sciences of the United States of America 20031209

Flavonoids as aryl hydrocarbon receptor agonists/antagonists: effects of structure and cell context.

Environmental health perspectives 20031201

Screening of the inhibitory effect of vegetable constituents on the aryl hydrocarbon receptor-mediated activity induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Biological & pharmaceutical bulletin 20031201

Drug/substance reversal effects of a novel tri-substituted benzoflavone moiety (BZF) isolated from Passiflora incarnata Linn.--a brief perspective.

Addiction biology 20031201

Analysis of propolis from the continental and Adriatic regions of Croatia.

Acta pharmaceutica (Zagreb, Croatia) 20031201

Synthesis, characterization and DNA-binding properties of La(III) complex of chrysin.

Journal of inorganic biochemistry 20031101

Ingestion of a dietary supplement containing dehydroepiandrosterone (DHEA) and androstenedione has minimal effect on immune function in middle-aged men.

Journal of the American College of Nutrition 20031001

Tricin from a malagasy connaraceous plant with potent antihistaminic activity.

Journal of natural products 20030901

Quantification of 6-deoxy-6-demethyl-4-dedimethylaminotetracycline (COL-3) in human plasma using liquid chromatography coupled with electrospray ionization tandem mass spectrometry.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030825

Effect of chrysin, a flavonoid compound, on the mutagenic activity of 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine (PhIP) and benzo(a)pyrene (B(a)P) in bacterial and human hepatoma (HepG2) cells.

Archives of toxicology 20030801

Antiprotozoal activity of the constituents of Teloxys graveolens.

Phytotherapy research : PTR 20030801

Synthesis and PGE2 inhibitory activity of vinylated and allylated chrysin analogues.

Archives of pharmacal research 20030801

Flavonoids from Calicotome villosa.

Fitoterapia 20030601

Synthesis and PGE2 inhibitory activity of 5,7-dihydroxyflavones and their O-methylated flavone analogs.

Archives of pharmacal research 20030501

Inhibitory effects of some flavonoids on the activity of mushroom tyrosinase.

Biochemistry. Biokhimiia 20030401

Synthesis and anticancer effect of chrysin derivatives.

Bioorganic & medicinal chemistry letters 20030310

Role of NAD(P)H:quinone oxidoreductase in the progression of neuronal cell death in vitro and following cerebral ischaemia in vivo.

Journal of neurochemistry 20030301

Isolation and identification of four flavonoid constituents from the seeds of Oroxylum indicum by high-speed counter-current chromatography.

Journal of chromatography. A 20030221

Flavonoid modulation of ionic currents mediated by GABA(A) and GABA(C) receptors.

European journal of pharmacology 20030214

Effect of flavonoids on MRP1-mediated transport in Panc-1 cells.

Journal of pharmaceutical sciences 20030201

Effect of flavone derivatives on interleukin-1beta (IL-1beta) mRNA expression and IL-1beta protein synthesis in stimulated RAW 264.7 macrophages.

Scandinavian journal of immunology 20030201

Insect antifeedant activity of flavones and chromones against Spodoptera litura.

Journal of agricultural and food chemistry 20030115

Effects of flavonoids on cisplatin-induced apoptosis of HL-60 and L1210 leukemia cells.

Leukemia research 20030101

Trypanocidal activity of Lychnophora staavioides Mart. (Vernonieae, Asteraceae).

Phytomedicine : international journal of phytotherapy and phytopharmacology 20030101

Cis-2', 3'-dihydrodiol production on flavone B-ring by biphenyl dioxygenase from Pseudomonas pseudoalcaligenes KF707 expressed in Escherichia coli.

Antonie van Leeuwenhoek 20030101

Effects of chrysin on urinary testosterone levels in human males.

Journal of medicinal food 20030101

Antioxidant and prooxidant effects of phenolics on pancreatic beta-cells in vitro.

Journal of agricultural and food chemistry 20021204

Pinostrobin from honey and Thai ginger (Boesenbergia pandurata): a potent flavonoid inducer of mammalian phase 2 chemoprotective and antioxidant enzymes.

Journal of agricultural and food chemistry 20021204

Structure-activity relationships of flavonoids, isolated from Scutellaria baicalensis, binding to benzodiazepine site of GABA(A) receptor complex.

Planta medica 20021201

Screening of ubiquitous plant constituents for COX-2 inhibition with a scintillation proximity based assay.

Journal of natural products 20021101

High-performance liquid chromatographic analysis of chrysin derivatives on a Nova-Pak C18 column.

Archives of pharmacal research 20021001

Effects of chronic chrysin treatment in spontaneously hypertensive rats.

Planta medica 20020901

GABA(A)-receptor ligands of flavonoid structure.

Current topics in medicinal chemistry 20020801

Antiproliferative constituents in plants 10. Flavones from the leaves of Lantana montevidensis Briq. and consideration of structure-activity relationship.

Biological & pharmaceutical bulletin 20020701

Relationship between estrogen receptor-binding and estrogenic activities of environmental estrogens and suppression by flavonoids.

Bioscience, biotechnology, and biochemistry 20020701

Induction of human UDP-glucuronosyltransferase UGT1A1 by flavonoids-structural requirements.

Drug metabolism and disposition: the biological fate of chemicals 20020501

Constituents of Chinese propolis and their antiproliferative activities.

Journal of natural products 20020501

Luteolin, a flavone, does not suppress postprandial glucose absorption through an inhibition of alpha-glucosidase action.

Bioscience, biotechnology, and biochemistry 20020301

Oxidation of the flavonoids galangin and kaempferide by human liver microsomes and CYP1A1, CYP1A2, and CYP2C9.

Drug metabolism and disposition: the biological fate of chemicals 20020201

Flavonoids inhibit genetic toxicity produced by carcinogens in cells expressing CYP1A2 and CYP1A1.

Mutagenesis 20020101

Chemical composition of European propolis: expected and unexpected results.

Zeitschrift fur Naturforschung. C, Journal of biosciences 20020101

Beneficial effects of chrysin and benzoflavone on virility in 2-year-old male rats.

Journal of medicinal food 20020101

Flavonoids with epidermal growth factor-receptor tyrosine kinase inhibitory activity stimulate PEPT1-mediated cefixime uptake into human intestinal epithelial cells.

The Journal of pharmacology and experimental therapeutics 20011001

No evidence for the in vivo activity of aromatase-inhibiting flavonoids.

The Journal of steroid biochemistry and molecular biology 20010901

Effects of androstenedione-herbal supplementation on serum sex hormone concentrations in 30- to 59-year-old men.

International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20010901

Different catalytic properties and inhibitor responses of the goldfish brain and ovary aromatase isozymes.

General and comparative endocrinology 20010801

Vasorelaxant effects of the bioflavonoid chrysin in isolated rat aorta.

Planta medica 20010801

3D-QSAR model of flavonoids binding at benzodiazepine site in GABAA receptors.

Journal of medicinal chemistry 20010607

Common phytochemicals are ecdysteroid agonists and antagonists: a possible evolutionary link between vertebrate and invertebrate steroid hormones.

The Journal of steroid biochemistry and molecular biology 20010601

Suppression of inducible cyclooxygenase and nitric oxide synthase through activation of peroxisome proliferator-activated receptor-gamma by flavonoids in mouse macrophages.

FEBS letters 20010504

Structure-activity relationships for a large diverse set of natural, synthetic, and environmental estrogens.

Chemical research in toxicology 20010301

C-Isoprenylation of flavonoids enhances binding affinity toward P-glycoprotein and modulation of cancer cell chemoresistance.

Journal of medicinal chemistry 20010301

Chemoprotective potentials of homoisoflavonoids and chalcones of Dracaena cinnabari: modulations of drug-metabolizing enzymes and antioxidant activity.

Phytotherapy research : PTR 20010301

Induction of UDP-glucuronosyltransferase UGT1A1 by the flavonoid chrysin in Caco-2 cells--potential role in carcinogen bioinactivation.

Pharmaceutical research 20010301

Flavonoids as peroxynitrite scavengers: the role of the hydroxyl groups.

Toxicology in vitro : an international journal published in association with BIBRA 20010201

Disposition and metabolism of the flavonoid chrysin in normal volunteers.

British journal of clinical pharmacology 20010201

Flavonolignan and flavone inhibitors of a Staphylococcus aureus multidrug resistance pump: structure-activity relationships.

Journal of medicinal chemistry 20010118

Induction of UDP-glucuronosyltransferase UGT1A1 by the flavonoid chrysin in the human hepatoma cell line hep G2.

Drug metabolism and disposition: the biological fate of chemicals 20000901

Cytotoxic activity of low molecular weight polyphenols against human oral tumor cell lines.

Anticancer research 20000101

Differential effects of dietary flavonoids on drug metabolizing and antioxidant enzymes in female rat.

Xenobiotica; the fate of foreign compounds in biological systems 19991201

Structure-activity relationships and molecular modeling analysis of flavonoids binding to the benzodiazepine site of the rat brain GABA(A) receptor complex.

Journal of medicinal chemistry 19991021

Inhibition of aromatase activity by flavonoids.

Archives of pharmacal research 19990601

Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta.

Endocrinology 19981001

Molecular basis of the inhibition of human aromatase (estrogen synthetase) by flavone and isoflavone phytoestrogens: A site-directed mutagenesis study.

Environmental health perspectives 19980201

Antitumor agents. 166. Synthesis and biological evaluation of 5,6,7,8-substituted-2-phenylthiochromen-4-ones.

Journal of medicinal chemistry 19960510

Inhibition of HIV activation in latently infected cells by flavonoid compounds.

AIDS research and human retroviruses 19960101

Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates.

Drug metabolism and disposition: the biological fate of chemicals 19940101

Anti-AIDS agents, 10. Acacetin-7-O-beta-D-galactopyranoside, an anti-HIV principle from Chrysanthemum morifolium and a structure-activity correlation with some related flavonoids.

Journal of natural products 19940101

Inhibition of HIV infection by flavanoids.

Antiviral research 19931001

Flavones are inhibitors of HIV-1 proteinase.

Biochemical and biophysical research communications 19921030

Differential inhibitory effects of various flavonoids on the activities of reverse transcriptase and cellular DNA and RNA polymerases.

European journal of biochemistry 19900705

Effects of propolis flavonoids on virus infectivity and replication.

Microbiologica 19900701