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4363-41-1

4363-41-1 | (E)-2-PHENYLETHYLENESULFONAMIDE

CAS No: 4363-41-1 Catalog No: AG00DGUE MDL No:MFCD00118353

Product Description

Catalog Number:
AG00DGUE
Chemical Name:
(E)-2-PHENYLETHYLENESULFONAMIDE
CAS Number:
4363-41-1
MDL Number:
MFCD00118353
IUPAC Name:
(E)-2-phenylethenesulfonamide
InChI:
InChI=1S/C8H9NO2S/c9-12(10,11)7-6-8-4-2-1-3-5-8/h1-7H,(H2,9,10,11)/b7-6+
InChI Key:
SHPHBMZZXHFXDF-VOTSOKGWSA-N
NSC Number:
85560

Properties

Complexity:
245  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
1  
Exact Mass:
183.035g/mol
Formal Charge:
0
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
183.225g/mol
Monoisotopic Mass:
183.035g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
68.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.9  

Literature

Title Journal
Interaction of the ARF tumor suppressor with cytosolic HSP70 contributes to its autophagy function. Cancer biology & therapy 20110915
HSP70 inhibition by the small-molecule 2-phenylethynesulfonamide impairs protein clearance pathways in tumor cells. Molecular cancer research : MCR 20110701
Inhibitor of heat shock protein is a potential anticancer drug, Penn study finds. Cancer biology & therapy 20091101
A small molecule inhibitor of inducible heat shock protein 70. Molecular cell 20091009

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