200,000+ products from a single source!
sales@angenechem.com
Home > Nitro Compounds > 42397-65-9
42397-65-9 | 1,8-Dinitropyrene
CAS No: 42397-65-9 Catalog No: AG003DS6 MDL No:
Product Description
Catalog Number:
AG003DS6
Chemical Name:
1,8-Dinitropyrene
CAS Number:
42397-65-9
IUPAC Name:
1,8-dinitropyrene
InChI:
InChI=1S/C16H8N2O4/c19-17(20)13-7-3-9-1-2-10-4-8-14(18(21)22)12-6-5-11(13)15(9)16(10)12/h1-8H
InChI Key:
BLYXNIHKOMELAP-UHFFFAOYSA-N
UNII:
51U7E9MW6I
Properties
Complexity:
442
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
292.048g/mol
Formal Charge:
0
Heavy Atom Count:
22
Hydrogen Bond Acceptor Count:
4
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
292.25g/mol
Monoisotopic Mass:
292.048g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
91.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
4.7
Literature
| Title | Journal |
|---|---|
| Mechanistic Investigations Into the Developmental Toxicity of Nitrated and Heterocyclic PAHs. | Toxicological sciences : an official journal of the Society of Toxicology 20170501 |
| Classification of polycyclic aromatic hydrocarbons based on mutagenicity in lung tissue through DNA microarray. | Environmental toxicology 20131101 |
| A new imidazolium-embedded C18 stationary phase with enhanced performance in reversed-phase liquid chromatography. | Analytica chimica acta 20120813 |
| Environmental nitration processes enhance the mutagenic potency of aromatic compounds. | Environmental toxicology 20120501 |
| Metabolic activation of diesel exhaust carcinogens in primary and immortalized human TP53 knock-in (Hupki) mouse embryo fibroblasts. | Environmental and molecular mutagenesis 20120401 |
| Genetic requirement for mutagenesis of the G[8,5-Me]T cross-link in Escherichia coli: DNA polymerases IV and V compete for error-prone bypass. | Biochemistry 20110329 |
| Nitroarenes (selected): 1,8-Dinitropyrene. | Report on carcinogens : carcinogen profiles 20110101 |
| Mutagenicity of surface soil from residential areas in Kyoto city, Japan, and identification of major mutagens. | Mutation research 20080108 |
| Mutagenicity of the 1-nitropyrene-DNA adduct N-(deoxyguanosin-8-yl)-1-aminopyrene in mammalian cells. | Chemical research in toxicology 20071101 |
| Effects of nitrated-polycyclic aromatic hydrocarbons and diesel exhaust particle extracts on cell signalling related to apoptosis: possible implications for their mutagenic and carcinogenic effects. | Toxicology 20070307 |
| Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. | Journal of molecular graphics & modelling 20061101 |
| Nitrocompound activation by cell-free extracts of nitroreductase-proficient Salmonella typhimurium strains. | Mutagenesis 20061101 |
| Detection of a novel mutagen, 3,6-dinitrobenzo[e]pyrene, as a major contaminant in surface soil in Osaka and Aichi Prefectures, Japan. | Chemical research in toxicology 20050201 |
| Oxidative DNA damage induced by carcinogenic dinitropyrenes in the presence of P450 reductase. | Chemical research in toxicology 20041201 |
| Nitroarenes (selected) 1,8-dinitropyrene. | Report on carcinogens : carcinogen profiles 20040101 |
| Mutagenic activity and quantification of nitroarenes in surface soil in the Kinki region of Japan. | Mutation research 20030708 |
| Comparative mutagenesis of the C8-guanine adducts of 1-nitropyrene and 1,6- and 1,8-dinitropyrene in a CpG repeat sequence. A slipped frameshift intermediate model for dinucleotide deletion. | The Journal of biological chemistry 20021122 |
| Induction of CYP1A1, CYP1A2, and CYP1B1 mRNAs by nitropolycyclic aromatic hydrocarbons in various human tissue-derived cells: chemical-, cytochrome P450 isoform-, and cell-specific differences. | Archives of toxicology 20020601 |
| Dinitropyrenes induce gene mutations in multiple organs of the lambda/lacZ transgenic mouse (Muta Mouse). | Mutation research 20020325 |
| Induction of sister chromatid exchanges and chromosome aberrations in cultured mammalian cells treated with aminophenylnorharman formed by norharman with aniline. | Mutation research 20020325 |
| Nitroarenes (selected). 1,8-Dinitropyrene. | Report on carcinogens : carcinogen profiles 20020101 |
| Catechins are not major components responsible for anti-genotoxic effects of tea extracts against nitroarenes. | Mutation research 20010920 |
| [Suppression of frameshift mutation as a result of partial inactivation of translation termination factors in Saccharomyces cerevisiae yeast]. | Genetika 20010501 |
| Bioactivation of diesel exhaust particle extracts and their major nitrated polycyclic aromatic hydrocarbon components, 1-nitropyrene and dinitropyrenes, by human cytochromes P450 1A1, 1A2, and 1B1. | Mutation research 20001220 |
| Carcinogenicity of nitropyrenes in the newborn female rat. | Carcinogenesis 19951201 |
| Decreased clastogenicity of dinitropyrenes in Chinese hamster lung (CHL) subclone cells with low NADPH-cytochrome P-450 reductase activity. | Mutation research 19910901 |
| Carcinogenicity of dinitropyrenes in the weanling female CD rat. | Carcinogenesis 19910701 |
| Purified NAD(P)H-quinone oxidoreductase enhances the mutagenicity of dinitropyrenes in vitro. | Journal of biochemical toxicology 19910101 |
| 1,8-Dinitropyrene: comparative mutagenicity in Chinese hamster V79 and CHO cells. | Mutagenesis 19900501 |
| Inactivation of 1,3-, 1,6-, and 1,8-dinitropyrene by cytochrome P-450 enzymes in human and rat liver microsomes. | Cancer research 19900401 |
| Metabolism and biological effects of nitropyrene and related compounds. | Research report (Health Effects Institute) 19880201 |
| Tumorigenicity test of 1,3- and 1,8-dinitropyrene in BALB/c mice. | Journal of the National Cancer Institute 19870701 |
| Tumorigenicity of nitrated derivatives of pyrene, benz[a]anthracene, chrysene and benzo[a]pyrene in the newborn mouse assay. | Carcinogenesis 19860801 |
| Structure of the c-Ki-ras gene in a rat fibrosarcoma induced by 1,8-dinitropyrene. | Molecular and cellular biology 19860401 |
| Dinitro derivatives of pyrene and fluoranthene in diesel emission particulates and their tumorigenicity in mice and rats. | Developments in toxicology and environmental science 19860101 |
| Carcinogenic effects of a mixture of nitropyrenes in F344 rats following its repeated oral administrations. | Developments in toxicology and environmental science 19860101 |
| Induction of 6-thioguanine resistance, chromosome aberrations and SCE by dinitropyrenes in Chinese hamster ovary cells in vitro. | Mutation research 19851201 |
| Activation of K-ras and oncogenes other than ras family in rat fibrosarcomas induced by 1,8-dinitropyrene. | Cancer letters 19851101 |
| DNA adduct formation and mutation induction by nitropyrenes in Salmonella and Chinese hamster ovary cells: relationships with nitroreduction and acetylation. | Environmental health perspectives 19851001 |
| Absence of carcinogenicity of 1-nitropyrene, correction of previous results, and new demonstration of carcinogenicity of 1,6-dinitropyrene in rats. | Cancer letters 19850101 |
| Induction of sarcomas in rats by subcutaneous injection of dinitropyrenes. | Carcinogenesis 19840501 |
| Tumor initiating activities of 1-nitropyrene and its nitrated products in SENCAR mice. | Cancer letters 19840501 |
| Mutagenicity of mono-, di- and tri-nitropyrenes in Chinese hamster ovary cells. | Mutation research 19830301 |
| Nitration of carcinogenic and non-carcinogenic polycyclic aromatic hydrocarbons results in products able to induce transformation of Syrian hamster cells. | Carcinogenesis 19830101 |
| The clastogenic activity of dinitropyrenes in a rat-liver epithelial cell line. | Mutation research 19821101 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.