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3902-71-4 | TRIOXSALEN
CAS No: 3902-71-4 Catalog No: AG003V59 MDL No:MFCD00005010
Product Description
Catalog Number:
AG003V59
Chemical Name:
TRIOXSALEN
CAS Number:
3902-71-4
Molecular Formula:
C14H12O3
Molecular Weight:
228.2433
MDL Number:
MFCD00005010
IUPAC Name:
2,5,9-trimethylfuro[3,2-g]chromen-7-one
InChI:
InChI=1S/C14H12O3/c1-7-4-12(15)17-14-9(3)13-10(6-11(7)14)5-8(2)16-13/h4-6H,1-3H3
InChI Key:
FMHHVULEAZTJMA-UHFFFAOYSA-N
SMILES:
Cc1cc2c(o1)c(C)c1c(c2)c(C)cc(=O)o1
EC Number:
223-459-0
UNII:
Y6UY8OV51T
Properties
Complexity:
374
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
228.079g/mol
Formal Charge:
0
Heavy Atom Count:
17
Hydrogen Bond Acceptor Count:
3
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
228.247g/mol
Monoisotopic Mass:
228.079g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
39.4A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3
Literature
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|---|---|
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| The HLH-6 transcription factor regulates C. elegans pharyngeal gland development and function. | PLoS genetics 20081001 |
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| Specific apoptosis induction in human papillomavirus-positive cervical carcinoma cells by photodynamic antisense regulation. | Oligonucleotides 20070101 |
| Counting mutagenized genomes and optimizing genetic screens in Caenorhabditis elegans. | PloS one 20070101 |
| Synthesis and biological in vitro evaluation of novel PEG-psoralen conjugates. | Biomacromolecules 20061201 |
| Permeability of psoralen derivatives in lipid membranes. | Biophysical journal 20061001 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Enhanced repair of DNA interstrand crosslinks in S phase. | FEBS letters 20060306 |
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| Occupational allergic contact dermatitis disseminated from multifunctional acrylates in ultraviolet-cured lacquers. | International journal of occupational medicine and environmental health 20060101 |
| TILLING is an effective reverse genetics technique for Caenorhabditis elegans. | BMC genomics 20060101 |
| Properties of novel antisense oligonucleotides containing 2'-O-modified adenosine with a photo-reactive group. | Nucleic acids symposium series (2004) 20060101 |
| Inhibition of interferon-gamma signaling by a mercurio-substituted dihydropsoralen in murine keratinocytes. | Biochemical pharmacology 20051205 |
| Repair of DNA interstrand crosslinks may take place at the nuclear matrix. | Journal of cellular biochemistry 20050901 |
| Psoralen photocrosslinking, a tool to study the chromatin structure of RNA polymerase I--transcribed ribosomal genes. | Biochemistry and cell biology = Biochimie et biologie cellulaire 20050801 |
| Spectral study of interactions of 4,8,4'-trimethylpsoralen and 4,4'-dimethylangelicin dyes with DNA. | Biochemistry. Biokhimiia 20050701 |
| Disappearance of nucleosome positioning in mitotic chromatin in vivo. | The Journal of biological chemistry 20050415 |
| Interplay between human high mobility group protein 1 and replication protein A on psoralen-cross-linked DNA. | Biochemistry 20050322 |
| 5-(3-Phenylpropoxy)psoralen and 5-(4-phenylbutoxy)psoralen: mechanistic studies on phototoxicity. | Die Pharmazie 20050301 |
| Identification of ciliated sensory neuron-expressed genes in Caenorhabditis elegans using targeted pull-down of poly(A) tails. | Genome biology 20050101 |
| Photoreaction of skin-sensitizing trimethyl psoralen with lipid membrane models. | Photochemistry and photobiology 20050101 |
| Synthesis and properties of photo-reactive antisense oligonucleotides containing 2'-O-psoralen-conjugated adenosine. | Nucleic acids symposium series (2004) 20050101 |
| Comparison of oral psoralen-UV-A with a portable tanning unit at home vs hospital-administered bath psoralen-UV-A in patients with chronic hand eczema: an open-label randomized controlled trial of efficacy. | Archives of dermatology 20041201 |
| Tandem mass spectrometry for the determination of the sites of DNA interstrand cross-link. | Journal of the American Society for Mass Spectrometry 20041101 |
| Psoralen derivatives and longwave ultraviolet irradiation are active in vitro against human melanoma cell line. | Journal of photochemistry and photobiology. B, Biology 20041025 |
| Identification of chaperonin CCT gamma subunit as a determinant of retinotectal development by whole-genome subtraction cloning from zebrafish no tectal neuron mutant. | Development (Cambridge, England) 20040501 |
| Defining the function of xeroderma pigmentosum group F protein in psoralen interstrand cross-link-mediated DNA repair and mutagenesis. | The Biochemical journal 20040401 |
| Shower PUVA: a novel variant of photochemotherapy. Distribution of photosensitivity and accumulation of trioxsalen in the skin. | Skin pharmacology and physiology 20040101 |
| Randomized half-side comparison of narrowband UVB and trimethylpsoralen bath plus UVA treatments for psoriasis. | Acta dermato-venereologica 20040101 |
| Nucleosome positioning in the human c-Fos promoter analyzed by in vivo footprinting with psoralen and ionizing radiation. | Biochemistry 20031230 |
| Determination of 8-methoxypsoralen in human plasma, and microdialysates using liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031225 |
| Structure elucidation of DNA interstrand cross-link by a combination of nuclease P1 digestion with mass spectrometry. | Analytical chemistry 20031115 |
| Representational difference analysis, high-resolution physical mapping, and transcript identification of the zebrafish genomic region for a motor behavior. | Genomics 20030801 |
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| Isolation of null alleles of the Caenorhabditis elegans gly-12, gly-13 and gly-14 genes, all of which encode UDP-GlcNAc: alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I activity. | Biochimie 20030101 |
| UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I and UDP-N-acetylglucosamine:alpha-6-D-mannoside beta-1,2-N-acetylglucosaminyltransferase II in Caenorhabditis elegans. | Biochimica et biophysica acta 20021219 |
| Binding affinities of commonly employed sensitizers of viral inactivation. | Photochemistry and photobiology 20020601 |
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| Cell-impermeant pyridinium derivatives of psoralens as inhibitors of keratinocyte growth. | Biochemical pharmacology 20020101 |
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| Mapping psoralen cross-links at the nucleotide level in mammalian cells: suppression of cross-linking at transcription factor- or nucleosome-binding sites. | Biochemistry 20010403 |
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| The effects of singlet oxygen produced by photodynamic action on the mitochondrial permeability transition differ in accordance with the localization of the sensitizer. | Archives of biochemistry and biophysics 20010215 |
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