CAS 3895-92-9 | 1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridiniumchloride | CAS Number 3895-92-9

Title	Journal
An Early and Robust Activation of Caspases Heads Cells for a Regulated Form of Necrotic-like Cell Death.	The Journal of biological chemistry 20150821
Protective effect of chelerythrine against ethanol-induced gastric ulcer in mice.	Chemico-biological interactions 20140205
Matching biochemical and functional efficacies confirm ZIP as a potent competitive inhibitor of PKMζ in neurons.	Neuropharmacology 20130101
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.	Bioorganic & medicinal chemistry 20121115
In vitro antifungal activity of sanguinarine and chelerythrine derivatives against phytopathogenic fungi.	Molecules (Basel, Switzerland) 20121102
Deoxycholic acid inhibits smooth muscle contraction via protein kinase C-dependent modulation of L-type Ca2+ channels in rat proximal colon.	Molecular medicine reports 20121001
Regulation of estradiol and progesterone production by CRH-R1 and -R2 is through divergent signaling pathways in cultured human placental trophoblasts.	Endocrinology 20121001
Involvement of basal and calcium-activated protein kinase C in neurotransmitter secretion in mouse motor synapses.	Bulletin of experimental biology and medicine 20121001
Luminescence and binding properties of two isoquinoline alkaloids chelerythrine and sanguinarine with ctDNA.	Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120901
Exercise preconditioning provides early cardioprotection against exhaustive exercise in rats: potential involvement of protein kinase C delta translocation.	Molecular and cellular biochemistry 20120901
Task demands dissociate the effects of muscarinic M1 receptor blockade and protein kinase C inhibition on attentional performance in rats.	Journal of psychopharmacology (Oxford, England) 20120801
[Effect of intrathecal sufentanil and protein kinase C inhibitor on pain threshold and the expression of NMDA receptor/ CGRP in spinal dorsal horn in rats with neuropathic pain].	Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20120801
Facilitation of neurotransmitter release in mouse motor synapses in different modes of protein kinase C activation.	Bulletin of experimental biology and medicine 20120801
Investigation of sanguinarine and chelerythrine effects on LPS-induced inflammatory gene expression in THP-1 cell line.	Phytomedicine : international journal of phytotherapy and phytopharmacology 20120715
Protein kinase C inhibitor prevents renal apoptotic and fibrotic changes in response to partial ureteric obstruction.	BJU international 20120701
Protein kinase C-α mediates hypertonicity-stimulated increase in urea transporter phosphorylation in the inner medullary collecting duct.	American journal of physiology. Renal physiology 20120501
Differential consequences of protein kinase C activation during early and late hepatic ischemic preconditioning.	The journal of physiological sciences : JPS 20120501
Cardioprotection of electroacupuncture against myocardial ischemia-reperfusion injury by modulation of cardiac norepinephrine release.	American journal of physiology. Heart and circulatory physiology 20120501
Protective effect of urantide against ischemia-reperfusion injury via protein kinase C and phosphtidylinositol 3'-kinase - Akt pathway.	Canadian journal of physiology and pharmacology 20120501
Protein kinase mζ is necessary for cocaine-induced synaptic potentiation in the ventral tegmental area.	Biological psychiatry 20120415
Cellular pharmacology of protein kinase Mζ (PKMζ) contrasts with its in vitro profile: implications for PKMζ as a mediator of memory.	The Journal of biological chemistry 20120413
Testosterone modulates platelet aggregation and endothelial cell growth through nitric oxide pathway.	The Journal of endocrinology 20120401
Fluvoxamine increased glutamate release by activating both 5-HT(3) and sigma-1 receptors in prelimbic cortex of chronic restraint stress C57BL/6 mice.	Biochimica et biophysica acta 20120401
Transient Ca2+ mobilization caused by osmotic shock initiates salmonid fish sperm motility.	The Journal of experimental biology 20120215
Role of stored calcium in the regulation of neurotransmitter quantum size.	Bulletin of experimental biology and medicine 20120201
Melatonin elicits protein kinase C-mediated calcium response in immortalized GT1-7 GnRH neurons.	Brain research 20120130
One-pot synthesis of isoquinolinium salts by rhodium-catalyzed C-H bond activation: application to the total synthesis of oxychelerythrine.	Angewandte Chemie (International ed. in English) 20120102
Physiological effect of protein kinase C on ENaC-mediated lung liquid regulation in the adult rat lung.	American journal of physiology. Lung cellular and molecular physiology 20120101
The proton-activated G protein coupled receptor OGR1 acutely regulates the activity of epithelial proton transport proteins.	Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Pharmacological differences of endothelin receptors-mediated modulation in cultured interstitial cells of Cajal from the murine small and large intestine.	Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Neuromedin S increases L-type Ca(2+) channel currents through G(i)α-protein and phospholipase C-dependent novel protein kinase C delta pathway in adult rat ventricular myocytes.	Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Reactive oxygen species-independent rapid initiation of mitochondrial apoptotic pathway by chelerythrine.	Toxicology in vitro : an international journal published in association with BIBRA 20111201
Formulation optimization of chelerythrine loaded O-carboxymethylchitosan microspheres using response surface methodology.	International journal of biological macromolecules 20111201
The ERM protein, ezrin, regulates neutrophil transmigration by modulating the apical localization of MRP2 in response to the SipA effector protein during Salmonella Typhimurium infection.	Cellular microbiology 20111201
Platelet-activating factor stimulates sodium-hydrogen exchange in ventricular myocytes.	American journal of physiology. Heart and circulatory physiology 20111201
KMUP-1 inhibits L-type Ca²⁺ channels involved the protein kinase C in rat basilar artery myocytes.	The Kaohsiung journal of medical sciences 20111201
Tumor necrosis factor-α downregulates sodium current in skeletal muscle by protein kinase C activation: involvement in critical illness polyneuromyopathy.	American journal of physiology. Cell physiology 20111101
Parathyroid hormone and the regulation of cell cycle in colon adenocarcinoma cells.	Biochimica et biophysica acta 20111001
Neurotensin inhibits background K+ channels and facilitates glutamatergic transmission in rat spinal cord dorsal horn.	The European journal of neuroscience 20111001
Rat lymphocytes express NMDA receptors that take part in regulation of cytokine production.	Cell biochemistry and function 20111001
β₁-adrenergic receptor up-regulation induced by nadolol is mediated via signal transduction pathway coupled to α₁-adrenergic receptors.	Brain research 20110926
Agonist-induced periodic vasomotion in rat isolated pulmonary artery.	Fundamental & clinical pharmacology 20110801
Activity of the chelerythrine, a quaternary benzo[c]phenanthridine alkaloid from Chelidonium majus L. on Dactylogyrus intermedius.	Parasitology research 20110701
Thyroid hormones modulate GABA(A) receptor-mediated currents in hippocampal neurons.	Neuropharmacology 20110601
Effects of chelerythrine, a specific inhibitor of cyclooxygenase-2, on acute inflammation in mice.	Fitoterapia 20110601
PKCgamma in Vc and C1/C2 is involved in trigeminal neuropathic pain.	Journal of dental research 20110601
Protein kinase C phosphorylates the cAMP response element binding protein in the hypothalamic paraventricular nucleus during morphine withdrawal.	British journal of pharmacology 20110601
Chelerythrine perturbs lamellar actomyosin filaments by selective inhibition of myotonic dystrophy kinase-related Cdc42-binding kinase.	FEBS letters 20110506
Antidepressant phenotype by inhibiting the phospholipase Cβ(1)--protein kinase Cγ pathway in the forced swim test.	Neuropharmacology 20110501
Differential effect of the benzophenanthridine alkaloids sanguinarine and chelerythrine on glycine transporters.	Neurochemistry international 20110501
The heart: a novel gonadotrophin-releasing hormone target.	Journal of neuroendocrinology 20110501
Identification of benzo[c]phenanthridine metabolites in human hepatocytes by liquid chromatography with electrospray ion-trap and quadrupole time-of-flight mass spectrometry.	Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110501
Structural modification of sanguinarine and chelerythrine and their antibacterial activity.	Natural product research 20110501
Induction of apoptosis by chelerythrine chloride through mitochondrial pathway and Bcl-2 family proteins in human hepatoma SMMC-7721 cell.	Archives of pharmacal research 20110501
Protein kinase M maintains long-term sensitization and long-term facilitation in aplysia.	The Journal of neuroscience : the official journal of the Society for Neuroscience 20110427
Microarray analysis of the chelerythrine-induced transcriptome of Mycobacterium tuberculosis.	Current microbiology 20110401
Hypoxia-induced sensitization of transient receptor potential vanilloid 1 involves activation of hypoxia-inducible factor-1 alpha and PKC.	Pain 20110401
Kisspeptin-10 elicits triphasic cytosolic calcium responses in immortalized GT1-7 GnRH neurones.	Neuroscience letters 20110329
A phospholipase A₂ isolated from Lachesis muta snake venom increases the survival of retinal ganglion cells in vitro.	Toxicon : official journal of the International Society on Toxinology 20110315
The actions of benzophenanthridine alkaloids, piperonyl butoxide and (S)-methoprene at the G-protein coupled cannabinoid CB₁ receptor in vitro.	European journal of pharmacology 20110301
Luteinizing hormone (LH) acts through PKA and PKC to modulate T-type calcium currents and intracellular calcium transients in mice Leydig cells.	Cell calcium 20110301
Effects of the PKC inhibitors chelerythrine and bisindolylmaleimide I (GF 109203X) on delayed rectifier K+ currents.	Naunyn-Schmiedeberg's archives of pharmacology 20110201
Characteristics of myogenic reactivity in isolated rat mesenteric veins.	American journal of physiology. Regulatory, integrative and comparative physiology 20110201
Protein kinase C modulates NMDA receptors in the myenteric plexus of the guinea pig ileum during in vitro ischemia and reperfusion.	Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20110201
Morphine postconditioning attenuates ICAM-1 expression on endothelial cells.	Journal of Korean medical science 20110201
Mechanism governing reversal of multidrug resistance in human breast carcinoma cells by chelerythrine.	Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20110201
Fos expression induced by activation of NMDA and neurokinin-1 receptors in the trigeminal subnucleus caudalis in vitro: role of protein kinases.	Brain research 20110112
Exercise preconditioning initiates late cardioprotection against isoproterenol-induced myocardial injury in rats independent of protein kinase C.	The journal of physiological sciences : JPS 20110101
L-type calcium channel β subunit modulates angiotensin II responses in cardiomyocytes.	Channels (Austin, Tex.) 20110101
Short-duration therapeutic hypothermia causes prompt connexin43 gap junction remodeling in isolated rabbit hearts.	Circulation journal : official journal of the Japanese Circulation Society 20110101
[Effect of vasopressin on the membrane potential of rat hepatocytes].	Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20110101
AT₁ receptor and NAD(P)H oxidase mediate angiotensin II-stimulated antioxidant enzymes and mitogen-activated protein kinase activity in the rat hypothalamus.	Journal of the renin-angiotensin-aldosterone system : JRAAS 20101201
Protein kinase C regulates urea permeability in the rat inner medullary collecting duct.	American journal of physiology. Renal physiology 20101201
Protein kinase C activation modulates reversible increase in cortical blood-brain barrier permeability and tight junction protein expression during hypoxia and posthypoxic reoxygenation.	Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20101101
TRPC6 channels stimulated by angiotensin II are inhibited by TRPC1/C5 channel activity through a Ca2+- and PKC-dependent mechanism in native vascular myocytes.	The Journal of physiology 20101001
Opioid peptide deltorphin II simulates the cardioprotective effect of ischemic preconditioning: role of δ₂-opioid receptors, protein kinase C, and K(ATP) channels.	Bulletin of experimental biology and medicine 20101001
Role of protein kinase Czeta in thrombin-induced RhoA activation and inter-endothelial gap formation of human dermal microvessel endothelial cell monolayers.	Microvascular research 20100901
Protein kinase A and C signaling induces bilirubin potentiation of GABA/glycinergic synaptic transmission in rat ventral cochlear nucleus neurons.	Brain research 20100812
Distinctions between persistent and reversible group I mGluR-induced epileptiform burst prolongation.	Epilepsia 20100801
[The study of effects and mechanism of U50, 488H on electrical coupling during ischemia in the perfused isolated rat heart].	Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20100801
Mechanism of inhibition of acetylcholine secretion in newly formed mouse synapses involving Ca2+-dependent kinases and voltage-gated K+-channels.	Bulletin of experimental biology and medicine 20100801
Rho kinase activation and ROS production contributes to the cooling enhanced contraction in cutaneous equine digital veins.	Journal of applied physiology (Bethesda, Md. : 1985) 20100701
Plant Natural compounds with antibacterial activity towards common pathogens of pond-cultured channel catfish (Ictalurus punctatus).	Toxins 20100701
Involvement of inositol-1,4,5-trisphosphate receptors in the bidirectional synaptic plasticity induced in hippocampal CA1 neurons by 1-10 Hz low-frequency stimulation.	Neuroscience 20100630
The identification of inhibitors of Schistosoma mansoni miracidial transformation by incorporating a medium-throughput small-molecule screen.	Experimental parasitology 20100601
Multiple kinase pathways regulate voltage-dependent Ca2+ influx and migration in oligodendrocyte precursor cells.	The Journal of neuroscience : the official journal of the Society for Neuroscience 20100505
[Role of protein kinase C in protecting rats against pulmonary ischemia reperfusion injury through opening of mitochondrial ATP sensitive potassium channel].	Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20100501
Activation of muscarinic M-1 cholinoceptors by curcumin to increase contractility in urinary bladder isolated from Wistar rats.	Neuroscience letters 20100405
Role of progesterone on the regulation of vascular muscle cells proliferation, migration and apoptosis.	Steroids 20100401
Rho kinase and protein kinase C involvement in vascular smooth muscle myofilament calcium sensitization in arteries from diabetic rats.	British journal of pharmacology 20100401
[Effects of a protein kinase C inhibitor combined with cisplatin on non-small cell lung cancer].	Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20100401
Role of Rho-kinase in mediating contraction of chicken embryo femoral arteries.	Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20100301
Regulation of K-Cl cotransport in erythrocytes of frog Rana temporaria by commonly used protein kinase and protein phosphatase inhibitors.	Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20100301
High glucose increases expression of cyclooxygenase-2, increases oxidative stress and decreases the generation of nitric oxide in mouse microvessel endothelial cells.	Journal of cellular physiology 20100301
Critical involvement of postsynaptic protein kinase activation in long-term potentiation at hippocampal mossy fiber synapses on CA3 interneurons.	The Journal of neuroscience : the official journal of the Society for Neuroscience 20100224
Attenuation of renal ischemia-reperfusion injury by postconditioning involves adenosine receptor and protein kinase C activation.	Transplant international : official journal of the European Society for Organ Transplantation 20100201
Involvement of protein kinase C-CPI-17 in androgen modulation of angiotensin II-renal vasoconstriction.	Cardiovascular research 20100201
Autophagy and protein kinase C are required for cardioprotection by sulfaphenazole.	American journal of physiology. Heart and circulatory physiology 20100201
Rift valley fever virus infection of human cells and insect hosts is promoted by protein kinase C epsilon.	PloS one 20100101
Inactivation of the Ecs ABC transporter of Staphylococcus aureus attenuates virulence by altering composition and function of bacterial wall.	PloS one 20100101
Antiproliferative and antiangiogenic effects of the benzophenanthridine alkaloid sanguinarine in melanoma.	Biochemical pharmacology 20091201
The membrane cytoskeletal protein adducin is phosphorylated by protein kinase C in D1 neurons of the nucleus accumbens and dorsal striatum following cocaine administration.	Journal of neurochemistry 20091201
PKC-permitted elevation of sarcolemmal KATP concentration may explain female-specific resistance to myocardial infarction.	The Journal of physiology 20091201
Rapid use-dependent down-regulation of gamma-aminobutyric acid type A receptors in rat mesencephalic trigeminal neurons.	Journal of neuroscience research 20091101
[Determination of chelerythrine in Chelidonium majus by RP-HPLC].	Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091101
Cardiac Na+ current regulation by pyridine nucleotides.	Circulation research 20091009
Cardiac metabolic state and Brugada syndrome: a link revealed.	Circulation research 20091009
Structure-activity relationship of isoform selective inhibitors of Rac1/1b GTPase nucleotide binding.	Bioorganic & medicinal chemistry letters 20091001
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.	Nature chemical biology 20091001
Antifungal activity of the benzo[c]phenanthridine alkaloids from Chelidonium majus Linn against resistant clinical yeast isolates.	Journal of ethnopharmacology 20090925
Selective sigma receptor agonist 2-(4-morpholinethyl)1-phenylcyclohexanecarboxylate (PRE084) promotes neuroprotection and neurite elongation through protein kinase C (PKC) signaling on motoneurons.	Neuroscience 20090804
Effect of protease-activated receptor 2 activation on single TRPV1 channel activities in rat vagal pulmonary sensory neurons.	Experimental physiology 20090801
Ragweed pollen-mediated IgE-independent release of biogenic amines from mast cells via induction of mitochondrial dysfunction.	Molecular immunology 20090801
Regulation of store-operated Ca2+ entry in pulmonary artery smooth muscle cells.	Cell calcium 20090801
Protective mechanisms of NO preconditioning against NO-induced apoptosis in H9c2 cells: role of PKC and COX-2.	Free radical research 20090801
[Studies on chemical constituents of fructus broussonetiae].	Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090801
Role of mitochondrial ATP-sensitive potassium channels on fatigue in mouse muscle fibers.	Biochemical and biophysical research communications 20090717
The anti-arrhythmic peptide AAP10 remodels Cx43 and Cx40 expression and function.	Naunyn-Schmiedeberg's archives of pharmacology 20090701
The role of nitric oxide and reactive oxygen species in the positive inotropic response to mechanical stretch in the mammalian myocardium.	Biochimica et biophysica acta 20090701
Relaxin alters cardiac myofilament function through a PKC-dependent pathway.	American journal of physiology. Heart and circulatory physiology 20090701
Delayed anti-arrhythmic effect of nitroglycerin in anesthetized rats: involvement of CGRP, PKC and mK ATP channels.	International journal of cardiology 20090626
Water taste transduction pathway is calcium dependent in Drosophila.	Chemical senses 20090601
Activation of peripheral delta2 opioid receptors increases cardiac tolerance to ischemia/reperfusion injury Involvement of protein kinase C, NO-synthase, KATP channels and the autonomic nervous system.	Life sciences 20090508
Protein kinase C activity is associated with prefrontal cortical decline in aging.	Neurobiology of aging 20090501
Direct evidence for the up-regulation of Vps34 regulated by PKCgamma during short-term treatment with morphine.	Synapse (New York, N.Y.) 20090501
A retrograde apoptotic signal originating in NGF-deprived distal axons of rat sympathetic neurons in compartmented cultures.	Cell research 20090501
Lysophosphatidic acid signaling promotes proliferation, differentiation, and cell survival in rat growth plate chondrocytes.	Biochimica et biophysica acta 20090501
CapZ dynamics are altered by endothelin-1 and phenylephrine via PIP2- and PKC-dependent mechanisms.	American journal of physiology. Cell physiology 20090501
Effects of desflurane and propofol on electrophysiological parameters during and recovery after hypoxia in rat hippocampal slice CA1 pyramidal cells.	Neuroscience 20090421
Rapid component I(Kr) of cardiac delayed rectifier potassium currents in guinea-pig is inhibited by alpha(1)-adrenoreceptor activation via protein kinase A and protein kinase C-dependent pathways.	European journal of pharmacology 20090417
Statins and fenofibrate affect skeletal muscle chloride conductance in rats by differently impairing ClC-1 channel regulation and expression.	British journal of pharmacology 20090401
Analysis of alkaloids in Macleaya cordata (Willd.) R. Br. using high-performance liquid chromatography with diode array detection and electrospray ionization mass spectrometry.	Journal of chromatography. A 20090313
Protein kinase C mediates amyloid beta-protein fragment 31-35-induced suppression of hippocampal late-phase long-term potentiation in vivo.	Neurobiology of learning and memory 20090301
Improvement of deficient natural killer activity and delayed bactericidal activity by a thiol proteinase inhibitor, E-64-d, in leukocytes from Chediak-Higashi syndrome patients in vitro.	International immunopharmacology 20090301
Role of oxidative stress in the natriuresis induced by central administration of angiotensin II.	Journal of the renin-angiotensin-aldosterone system : JRAAS 20090301
Bradykinin regulates calpain and proinflammatory signaling through TRPM7-sensitive pathways in vascular smooth muscle cells.	American journal of physiology. Regulatory, integrative and comparative physiology 20090201
Obligatory role for phosphatidylinositol 4,5-bisphosphate in activation of native TRPC1 store-operated channels in vascular myocytes.	The Journal of physiology 20090201
Effect of curcumin on acidic pH-induced expression of IL-6 and IL-8 in human esophageal epithelial cells (HET-1A): role of PKC, MAPKs, and NF-kappaB.	American journal of physiology. Gastrointestinal and liver physiology 20090201
Two PKC consensus sites on human acid-sensing ion channel 1b differentially regulate its function.	American journal of physiology. Cell physiology 20090201
Synthesis and structure-activity relationships of novel, substituted 5,6-dihydrodibenzo[a,g]quinolizinium P2X7 antagonists.	Bioorganic & medicinal chemistry letters 20090201
Contribution of RhoA kinase and protein kinase C to weak relaxant effect of pinacidil on carbachol-induced contractions in sensitized guinea-pig trachealis.	Archives of pharmacal research 20090201
[The effect of chelerythrine on the hypertrophy of cardiac myocytes of neonatal rats induced by different glucose levels and its mechanism].	Yao xue xue bao = Acta pharmaceutica Sinica 20090201
[Mechanisms of gross saponins of Tribulus terrestris via activating PKCepsilon against myocardial apoptosis induced by oxidative stress].	Yao xue xue bao = Acta pharmaceutica Sinica 20090201
Angiotensin II stimulates water and NaCl intake through separate cell signalling pathways in rats.	Experimental physiology 20090101
Structural and functional similarity between the bacterial type III secretion system needle protein PrgI and the eukaryotic apoptosis Bcl-2 proteins.	PloS one 20090101
Cholinergic excitation of dopaminergic cells depends on sequential activation of protein kinase C and the L-type calcium channel in ventral tegmental area slices.	Brain research 20081215
The antimanic-like effect of tamoxifen: Behavioural comparison with other PKC-inhibiting and antiestrogenic drugs.	Progress in neuro-psychopharmacology & biological psychiatry 20081212
Adenosine A2A and beta-adrenergic calcium transient and contractile responses in rat ventricular myocytes.	American journal of physiology. Heart and circulatory physiology 20081201
Natural feed additive of Macleaya cordata: safety assessment in rats a 90-day feeding experiment.	Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081201
PKMzeta maintains spatial, instrumental, and classically conditioned long-term memories.	PLoS biology 20081201
Iodine-mediated electrophilic cyclization of 2-alkynyl-1-methylene azide aromatics leading to highly substituted isoquinolines and its application to the synthesis of norchelerythrine.	Journal of the American Chemical Society 20081119
Structure-activity relationship studies of phenanthridine-based Bcl-XL inhibitors.	Journal of medicinal chemistry 20081113
Modulation of Na+-H+ exchange isoforms NHE1 and NHE3 by insulin-like growth factor-1 in isolated bovine articular chondrocytes.	Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20081101
Impact of protein kinase C activation on epileptiform activity in the hippocampal slice.	Epilepsy research 20081101
Effects of 18-glycyrrhetinic acid on serine 368 phosphorylation of connexin43 in rat neonatal cardiomyocytes.	Cell biology international 20081101
Activation of the RAF/mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase pathway mediates apoptosis induced by chelerythrine in osteosarcoma.	Clinical cancer research : an official journal of the American Association for Cancer Research 20081015
Testosterone and dihydrotestosterone inhibit gallbladder motility through multiple signalling pathways.	Steroids 20081001
Calcium sensitization in human esophageal muscle: role for RhoA kinase in maintenance of lower esophageal sphincter tone.	The Journal of pharmacology and experimental therapeutics 20081001
Vasoactive intestinal peptide increases cystic fibrosis transmembrane conductance regulator levels in the apical membrane of Calu-3 cells through a protein kinase C-dependent mechanism.	The Journal of pharmacology and experimental therapeutics 20081001
Site-specific binding of chelerythrine and sanguinarine to single pyrimidine bulges in hairpin DNA.	Analytical and bioanalytical chemistry 20081001
Production of hydrogen peroxide and redox cycling can explain how sanguinarine and chelerythrine induce rapid apoptosis.	Archives of biochemistry and biophysics 20080901
Comparison of the involvement of protein kinase C in agonist-induced contractions in mouse aorta and corpus cavernosum.	European journal of pharmacology 20080820
N-oleoyldopamine, a novel endogenous capsaicin-like lipid, protects the heart against ischemia-reperfusion injury via activation of TRPV1.	American journal of physiology. Heart and circulatory physiology 20080801
Nitric oxide induces heat shock protein 72 production and delayed protection against myocardial ischemia in rabbits via activating protein kinase C.	Chinese medical journal 20080620
Insulin effects on cardiac Na+/Ca2+ exchanger activity: role of the cytoplasmic regulatory loop.	The Journal of biological chemistry 20080613
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).	Journal of medicinal chemistry 20080612
Chelerythrine and dihydrochelerythrine induce G1 phase arrest and bimodal cell death in human leukemia HL-60 cells.	Toxicology in vitro : an international journal published in association with BIBRA 20080601
Volume-sensitive NADPH oxidase activity and taurine efflux in NIH3T3 mouse fibroblasts.	American journal of physiology. Cell physiology 20080601
Apelin decreases the SR Ca2+ content but enhances the amplitude of [Ca2+]i transient and contractions during twitches in isolated rat cardiac myocytes.	American journal of physiology. Heart and circulatory physiology 20080601
Complex regulation of store-operated Ca2+ entry pathway by PKC-epsilon in vascular SMCs.	American journal of physiology. Cell physiology 20080601
Role of PKCepsilon in PGF2alpha-stimulated MMP-2 secretion from human ciliary muscle cells.	Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20080601
Macleaya cordata extract and Sangrovit genotoxicity. Assessment in vivo.	Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20080601
Separation of sanguinarine and chelerythrine in Macleaya cordata (Willd) R. Br. based on methyl acrylate-co-divinylbenzene macroporous adsorbents.	Journal of chromatography. A 20080523
Diverse properties of store-operated TRPC channels activated by protein kinase C in vascular myocytes.	The Journal of physiology 20080515
The increase in retinal cells proliferation induced by FGF2 is mediated by tyrosine and PI3 kinases.	Neurochemical research 20080501
Molecular interaction in the mouse PAG between NMDA and opioid receptors in morphine-induced acute thermal nociception.	Journal of neurochemistry 20080401
Epinephrine increases phosphorylation of MAP-2c in rat pheochromocytoma cells (PC12 Cells) via a protein kinase C- and mitogen activated protein kinase-dependent mechanism.	Journal of proteome research 20080401
A decisive role of mitochondria in defining rate and intensity of apoptosis induction by different alkaloids.	Toxicology letters 20080401
Chelerythrine induces apoptosis through a Bax/Bak-independent mitochondrial mechanism.	The Journal of biological chemistry 20080328
Chelerythrine treatment influences the balance of pro- and anti-apoptotic signaling pathways in the remote myocardium after infarction.	Molecular and cellular biochemistry 20080301
Low-dose morphine induces hyperalgesia through activation of G alphas, protein kinase C, and L-type Ca 2+ channels in rats.	Journal of neuroscience research 20080201
Differential effect of sanguinarine, chelerythrine and chelidonine on DNA damage and cell viability in primary mouse spleen cells and mouse leukemic cells.	Cell biology international 20080201
Conventional protein kinase C isoenzymes undergo dephosphorylation in neutrophil-like HL-60 cells treated by chelerythrine or sanguinarine.	Cell biology and toxicology 20080101
Cardioprotection induced by hydrogen sulfide preconditioning involves activation of ERK and PI3K/Akt pathways.	Pflugers Archiv : European journal of physiology 20080101
Identification of a PKCepsilon-dependent regulation of myocardial contraction by epicatechin-3-gallate.	American journal of physiology. Heart and circulatory physiology 20080101
H2S preconditioning-induced PKC activation regulates intracellular calcium handling in rat cardiomyocytes.	American journal of physiology. Cell physiology 20080101
Sevoflurane enhances ethanol-induced cardiac preconditioning through modulation of protein kinase C, mitochondrial KATP channels, and nitric oxide synthase, in guinea pig hearts.	Anesthesia and analgesia 20080101
[Changes in the DNA content in EGF-stimulated ciliate Tetrahymena pyriformis under effect of caffeine, KCl, and inhibitors of PLC and PKC].	Tsitologiia 20080101
[Effect of ionising irradiation on outward potassium current in the aorta smooth muscle cells in rats: the role of protein kinase C].	Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20080101
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.	Proceedings of the National Academy of Sciences of the United States of America 20071218
Opening the calcium-activated potassium channel participates in the cardioprotective effect of puerarin.	European journal of pharmacology 20071128
Disuse of rat muscle in vivo reduces protein kinase C activity controlling the sarcolemma chloride conductance.	The Journal of physiology 20071101
Oxytocin and vasopressin stimulate anion secretion by human and porcine vas deferens epithelia.	Biology of reproduction 20070901
Oxidative stress and increased eNOS and NADPH oxidase expression in mouse microvessel endothelial cells.	Journal of cellular physiology 20070901
Ischemic preconditioning targets the reperfusion phase.	Basic research in cardiology 20070901
Protein kinase C protects preconditioned rabbit hearts by increasing sensitivity of adenosine A2b-dependent signaling during early reperfusion.	Journal of molecular and cellular cardiology 20070901
Berberine suppresses inflammatory agents-induced interleukin-1beta and tumor necrosis factor-alpha productions via the inhibition of IkappaB degradation in human lung cells.	Pharmacological research 20070901
PKC activation sets an upper limit to the functional plasticity of GABAergic transmission induced by endogenous neurosteroids.	The European journal of neuroscience 20070901
Signal transduction mechanisms of CD137 ligand in human monocytes.	Cellular signalling 20070901
Involvement of the protein kinase Cgamma isoform in development of tolerance to nitrous oxide-induced antinociception in mice.	Neuroscience 20070824
Urocortin prevents mitochondrial permeability transition in response to reperfusion injury indirectly by reducing oxidative stress.	American journal of physiology. Heart and circulatory physiology 20070801
Localization of intracellular compartments that exchange Na,K-ATPase molecules with the plasma membrane in a hormone-dependent manner.	British journal of pharmacology 20070801
A minor role for Ca2+ sensitization in sustained contraction through activation of muscarinic receptor in circular muscle of rat distal colon.	Pflugers Archiv : European journal of physiology 20070701
Landiolol has cardioprotective effects against reperfusion injury in the rat heart via the PKCepsilon signaling pathway.	Free radical research 20070701
Role of L-type calcium channels and PKC in active tone development in rabbit coronary artery.	American journal of physiology. Heart and circulatory physiology 20070601
Protein kinase C regulates vascular myogenic tone through activation of TRPM4.	American journal of physiology. Heart and circulatory physiology 20070601
Verrucotoxin inhibits KATP channels in cardiac myocytes through a muscarinic M3 receptor-PKC pathway.	European journal of pharmacology 20070601
Delayed protection of tetramethylpyrazine on neonatal rat cardiomyocytes subjected to anoxia-reoxygenation injury.	Basic & clinical pharmacology & toxicology 20070601
[Effect of Chelerythrine on glucosyltransferase and water-insoluble glucan of Streptococcus mutans].	Shanghai kou qiang yi xue = Shanghai journal of stomatology 20070601
Effects of PKC on inhibition of delayed rectifier potassium currents by N/OFQ.	Biochemical and biophysical research communications 20070511
PKC blockade differentially affects aversive but not appetitive gustatory memories.	Brain research 20070507
M1 muscarinic receptor modulation of Kir2 channels enhances temporal summation of excitatory synaptic potentials in prefrontal cortex pyramidal neurons.	Journal of neurophysiology 20070501
Taurodeoxycholate modulates apical Cl-/OH- exchange activity in Caco2 cells.	Digestive diseases and sciences 20070501
Endothelin-1 accentuates the proatherosclerotic effects associated with C-reactive protein.	The Journal of thoracic and cardiovascular surgery 20070501
The pH hypothesis of postconditioning: staccato reperfusion reintroduces oxygen and perpetuates myocardial acidosis.	Circulation 20070410
Role of protein kinase C in aldosterone-induced non-genomic inhibition of basolateral potassium channels in human colonic crypts.	The Journal of steroid biochemistry and molecular biology 20070401
Extracellular signal-regulated kinase 1/2-mediated transcriptional regulation of G-protein-coupled receptor kinase 3 expression in neuronal cells.	The Journal of pharmacology and experimental therapeutics 20070401
A61603-induced contractions of the porcine meningeal artery are mediated by alpha1- and alpha2-adrenoceptors.	Basic & clinical pharmacology & toxicology 20070401
Cardioprotective properties of humoral factors released from rat hearts subject to ischemic preconditioning.	Journal of cardiovascular pharmacology 20070401
Receptor regulation of the volume-sensitive efflux of taurine and iodide from human SH-SY5Y neuroblastoma cells: differential requirements for Ca(2+) and protein kinase C.	The Journal of pharmacology and experimental therapeutics 20070301
Variability in the yield of benzophenanthridine alkaloids in wildcrafted vs cultivated bloodroot (Sanguinaria canadensis L.).	Journal of agricultural and food chemistry 20070221
(+/-)3,4-Methylenedioxyamphetamine elicits action potential bursts in a central snail neuron.	Experimental neurology 20070201
Protein kinase C-mediated modulation of glutamate transporter activity in rat retina.	Current eye research 20070201
[Effect of Chelerythrine on cell surface hydrophobicity and adherence of Streptococcus mutans].	Shanghai kou qiang yi xue = Shanghai journal of stomatology 20070201
Activation of kappa-opioid receptor as a method for prevention of ischemic and reperfusion arrhythmias: role of protein kinase C and K(ATP) channels.	Bulletin of experimental biology and medicine 20070201
Synaptic strength at the thalamocortical input to layer IV neonatal barrel cortex is regulated by protein kinase C.	Neuropharmacology 20070101
Two distinct signaling pathways for regulation of spontaneous local Ca2+ release by phospholipase C in airway smooth muscle cells.	Pflugers Archiv : European journal of physiology 20070101
Postjunctional synergism of norepinephrine with ATP and diadenosine tetraphosphate in Guinea pig vas deferens. Role of protein kinase C and Myosin light chain phosphatase.	Pharmacology 20070101
[Effect of adrenocorticotropic hormone on the caspase-3 level and DNA fragmentation in hyperplasia tissue of human adrenals].	Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20070101
Angiotensin II activates two cation conductances with distinct TRPC1 and TRPC6 channel properties in rabbit mesenteric artery myocytes.	The Journal of physiology 20061201
Chelerythrine and sanguinarine dock at distinct sites on BclXL that are not the classic BH3 binding cleft.	Journal of molecular biology 20061201
Positive inotropic effects of carbon monoxide-releasing molecules (CO-RMs) in the isolated perfused rat heart.	British journal of pharmacology 20061201
Nucleotide regulation of the voltage-dependent nonselective cation conductance in murine colonic myocytes.	American journal of physiology. Cell physiology 20061101
Characterization of beta-hexosaminidase secretion in rabbit lacrimal gland.	Experimental eye research 20061101
The effect of chelerythrine on cell growth, apoptosis, and cell cycle in human normal and cancer cells in comparison with sanguinarine.	Cell biology and toxicology 20061101
Bone marrow cells have a potent anti-ischemic effect against myocardial cell death in humans.	The Journal of thoracic and cardiovascular surgery 20061101
Preconditioning by 17beta-estradiol in isolated rat heart depends on PI3-K/PKB pathway, PKC, and ROS.	American journal of physiology. Heart and circulatory physiology 20061001
Signal transduction pathways involved in non-genomic action of estrone on vascular tissue.	Steroids 20061001
FRET analysis reveals a critical conformational change within the Na,K-ATPase alpha1 subunit N-terminus during GPCR-dependent endocytosis.	FEBS letters 20060918
Effects of hyposmotic stress on exocytosis in isolated turbot, Scophthalmus maximus, hepatocytes.	Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20060901
Calcium channel and glutamate receptor activities regulate actin organization in salamander retinal neurons.	The Journal of physiology 20060901
Quaternary benzo[c]phenathridine alkaloids sanguinarine and chelerythrine do not affect transcriptional activity of aryl hydrocarbon receptor: analyses in rat hepatoma cell line H4IIE.luc.	Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060901
Is protein kinase C (PKC) involved in nociception?	The International journal of neuroscience 20060901
DNA-binding affinities and sequence selectivity of quaternary benzophenanthridine alkaloids sanguinarine, chelerythrine, and nitidine.	Bioorganic & medicinal chemistry 20060815
Phosphorylation at the hydrophobic site of protein kinase C Apl II is increased during intermediate term facilitation.	Neuroscience 20060811
Modulation of cardiac sarcoplasmic reticulum calcium release by aenosine: a protein kinase C- dependent pathway.	Molecular and cellular biochemistry 20060801
Signalling pathways involved in hypertonicity- and acidification-induced activation of Na+/H+ exchange in trout hepatocytes.	The Journal of experimental biology 20060801
[Protective effect of protein kinase C and mitogen-activated protein kinases and its mechanism in liver ischemic preconditioning].	Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20060801
Elevated endothelin-1 levels impair nitric oxide homeostasis through a PKC-dependent pathway.	Circulation 20060704
Relaxin family peptide receptors RXFP1 and RXFP2 modulate cAMP signaling by distinct mechanisms.	Molecular pharmacology 20060701
Novel alpha1-adrenergic receptor signaling pathways: secreted factors and interactions with the extracellular matrix.	Molecular pharmacology 20060701
Rho-kinase contributes to hypoxia/reoxygenation-induced cerebral endothelial dysfunction.	Journal of cardiovascular pharmacology 20060701
Effects of sanguinarine and chelerythrine on the cell cycle and apoptosis.	Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20060701
Protein kinase C zeta mediates epidermal growth factor-induced growth of head and neck tumor cells by regulating mitogen-activated protein kinase.	Cancer research 20060615
Apoptotic response of uveal melanoma cells upon treatment with chelidonine, sanguinarine and chelerythrine.	Cancer letters 20060608
Recent advances in targeting regulators of apoptosis in cancer cells for therapeutic gain.	Expert opinion on investigational drugs 20060601
[Experimental study of the inhibitory effects of Chelidonium majus L. extractive on Streptococcus mutans in vitro].	Shanghai kou qiang yi xue = Shanghai journal of stomatology 20060601
Activation of protein kinase C enhances 1-methyl-4-phenylpyridinium ion (MPP+)-induced hydroxylradical generation in rat striatum.	Neuroscience letters 20060501
PI3K is required for insulin-stimulated but not EGF-stimulated ERK1/2 activation.	European journal of cell biology 20060501
Infarct-sparing effect of myocardial postconditioning is dependent on protein kinase C signalling.	Cardiovascular research 20060501
Postconditioning protects rabbit hearts through a protein kinase C-adenosine A2b receptor cascade.	Cardiovascular research 20060501
Involvement of protein kinase C in 5-HT-evoked thermal hyperalgesia and spinal fos protein expression in the rat.	Pharmacology, biochemistry, and behavior 20060501
The mitochondrial effects of small organic ligands of BCL-2: sensitization of BCL-2-overexpressing cells to apoptosis by a pyrimidine-2,4,6-trione derivative.	The Journal of biological chemistry 20060414
Geranylgeranylacetone, a noninvasive heat shock protein inducer, induces protein kinase C and leads to neuroprotection against cerebral infarction in rats.	Neuroscience letters 20060403
Role of protein kinase C in the effect of ATP on contractile function of the isolated strip from mouse diaphragm.	Bulletin of experimental biology and medicine 20060401
The beneficial in vitro effects of lovastatin and chelerythrine on relaxatory response to acetylcholine in the perfused mesentric bed isolated from diabetic rats.	European journal of pharmacology 20060327
Protein kinase C inhibitor chelerythrine attenuates the morphine-induced excitatory amino acid release and reduction of the antinociceptive effect of morphine in rats injected intrathecally with pertussis toxin.	Life sciences 20060313
Angiotensin II acutely decreases myocardial stiffness: a novel AT1, PKC and Na+/H+ exchanger-mediated effect.	British journal of pharmacology 20060301
Salviae miltiorrhizae radix increases dopamine release of rat and pheochromocytoma PC12 cells.	Phytotherapy research : PTR 20060301
Effects of intravenous anesthetics on the activity of glutamate transporter EAAT3 expressed in Xenopus oocytes: evidence for protein kinase C involvement.	European journal of pharmacology 20060215
Investigation of sanguinarine and chelerythrine effects on CYP1A1 expression and activity in human hepatoma cells.	Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060201
Reduction of infarct size with D-myo-inositol trisphosphate: role of PI3-kinase and mitochondrial K(ATP) channels.	American journal of physiology. Heart and circulatory physiology 20060201
Protective effect of chelerythrine on gentamicin-induced nephrotoxicity.	Cell biochemistry and function 20060101
Impact of inhibition of Qo site of mitochondrial complex III with myxothiazol on persistent sodium currents via superoxide and protein kinase C in rat hippocampal CA1 cells.	Neurobiology of disease 20060101
Palmitate induces tumor necrosis factor-alpha expression in C2C12 skeletal muscle cells by a mechanism involving protein kinase C and nuclear factor-kappaB activation.	Endocrinology 20060101
Regulation of cardiac inwardly rectifying potassium current IK1 and Kir2.x channels by endothelin-1.	Journal of molecular medicine (Berlin, Germany) 20060101
Inhibition of experimental proliferative vitreoretinopathy with protein kinase C inhibitor (chelerythrine chloride) and melatonin.	Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20060101
Human metallothionein gene expression is upregulated by beta-thujaplicin: possible involvement of protein kinase C and reactive oxygen species.	Biological & pharmaceutical bulletin 20060101
Lysophosphatidylcholine augments Ca(v)3.2 but not Ca(v)3.1 T-type Ca(2+) channel current expressed in HEK-293 cells.	Pharmacology 20060101
Analysis of secondary metabolites from eschscholtzia californica by high-performance liquid chromatography.	Phytochemical analysis : PCA 20060101
Role of oxidative/nitrosative stress in the tolerance to ischemia/reperfusion injury in cardiomyopathic hamster heart.	Antioxidants & redox signaling 20060101
Rapid determination of protopine, allocryptopine, sanguinarine and chelerythrine in fruits of Macleaya cordata by microwave-assisted solvent extraction and HPLC-ESI/MS.	Phytochemical analysis : PCA 20060101
Site-specific binding of chelerythrine to single cytosine and thymine bulges in DNA hairpins.	Nucleic acids symposium series (2004) 20060101
Gender differences in cardioprotection against ischemia/reperfusion injury in adult rat hearts: focus on Akt and protein kinase C signaling.	The Journal of pharmacology and experimental therapeutics 20051201
Aldosterone and tight junctions: modulation of claudin-4 phosphorylation in renal collecting duct cells.	American journal of physiology. Cell physiology 20051201
Pivotal role of NOX-2-containing NADPH oxidase in early ischemic preconditioning.	FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051201
Relative contribution of Rho kinase and protein kinase C to myogenic tone in rat cerebral arteries in hypertension.	American journal of physiology. Heart and circulatory physiology 20051101
Activation of PKC modulates blood-brain barrier endothelial cell permeability changes induced by hypoxia and posthypoxic reoxygenation.	American journal of physiology. Heart and circulatory physiology 20051101
Hepatic injury in rats with obstructive jaundice: roles of the protein kinase C signal pathway and cytoprotection of fructose.	Hepatobiliary & pancreatic diseases international : HBPD INT 20051101
Effects of chronic exposure to ethanol on glutamate transporter EAAT3 expressed in Xenopus oocytes: evidence for protein kinase C involvement.	Alcoholism, clinical and experimental research 20051101
Subcellular localization of iron regulatory proteins to Golgi and ER membranes.	Journal of cell science 20051001
Divergent regulation of Pyk2/CAKbeta phosphorylation by Ca2+ and cAMP in the hippocampus.	Biochimica et biophysica acta 20050930
Role of the protein kinase C-epsilon-Raf-1-MEK-1/2-p44/42 MAPK signaling cascade in the activation of signal transducers and activators of transcription 1 and 3 and induction of cyclooxygenase-2 after ischemic preconditioning.	Circulation 20050927
Effects of the limited analyte solubility on its mobility and zone shape: electrophoretic behavior of sanguinarine and chelerythrine around pH 7.	Electrophoresis 20050901
Pharmacological preconditioning with bradykinin affords myocardial protection through NO-dependent mechanisms.	International heart journal 20050901
Mechanisms of erythropoietin-mediated cardioprotection during ischemia-reperfusion injury: role of protein kinase C and phosphatidylinositol 3-kinase signaling.	FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050801
Modulation of tumor necrosis factor-alpha and oxidative stress through protein kinase C and P42/44 mitogen-activated protein kinase in lead increases lipopolysaccharide-induced liver damage in rats.	Shock (Augusta, Ga.) 20050801
Highly stable phenanthridinium frameworks as a new class of tunable DNA binding agents with cytotoxic properties.	Journal of medicinal chemistry 20050714
NAD(P)H-dependent superoxide production in platelets: the role of angiotensin II and protein kinase C.	Clinical biochemistry 20050701
AMPA receptor stimulation increases alpha5beta1 integrin surface expression, adhesive function and signaling.	Journal of neurochemistry 20050701
Mechanisms of the protective effects of urocortin on coronary endothelial function during ischemia-reperfusion in rat isolated hearts.	British journal of pharmacology 20050601
Annexin-1 peptide Anx-1(2-26) protects adult rat cardiac myocytes from cellular injury induced by simulated ischaemia.	British journal of pharmacology 20050601
Cardioprotective effects of Ilex paraguariensis extract: evidence for a nitric oxide-dependent mechanism.	Clinical nutrition (Edinburgh, Scotland) 20050601
The interaction of isoflurane and protein kinase C-activators on sarcolemmal KATP channels.	Anesthesia and analgesia 20050601
Study of the inhibition of alpha-amylase by the benzo[c]phenanthridine alkaloids sanguinarine and chelerythrine.	Journal of enzyme inhibition and medicinal chemistry 20050601
Protein kinase C is selectively involved in the mechanisms of long-term synaptic plasticity.	Bulletin of experimental biology and medicine 20050601
Platelet-activating factor induces cardioprotection in isolated rat heart akin to ischemic preconditioning: role of phosphoinositide 3-kinase and protein kinase C activation.	American journal of physiology. Heart and circulatory physiology 20050501
Remifentanil mimics cardioprotective effect of ischemic preconditioning via protein kinase C activation in open chest of rats.	Acta pharmacologica Sinica 20050501
In vitro assessment of cytotoxic agent combinations for hormone-refractory prostate cancer treatment.	Anti-cancer drugs 20050401
Antecedent ethanol ingestion prevents postischemic leukocyte adhesion and P-selectin expression by a protein kinase C-dependent mechanism.	Digestive diseases and sciences 20050401
Induction of human leukemia HL-60 cell differentiation via a PKC/ERK pathway by helenalin, a pseudoguainolide sesquiterpene lactone.	European journal of pharmacology 20050328
Staurosporine inhibits voltage-dependent K+ current through a PKC-independent mechanism in isolated coronary arterial smooth muscle cells.	Journal of cardiovascular pharmacology 20050301
Global kinase screening. Applications of frontal affinity chromatography coupled to mass spectrometry in drug discovery.	Analytical chemistry 20050301
Hypotonic shock mediation by p38 MAPK, JNK, PKC, FAK, OSR1 and SPAK in osmosensing chloride secreting cells of killifish opercular epithelium.	The Journal of experimental biology 20050301
Protein kinase C zeta is required for epidermal growth factor-induced chemotaxis of human breast cancer cells.	Cancer research 20050215
Signal transduction of the prophenoloxidase activating system of prawn haemocytes triggered by CpG oligodeoxynucleotides.	Fish & shellfish immunology 20050201
Protein kinase C delta is not activated by caspase-3 and its inhibition is sufficient to induce apoptosis in the colon cancer line, COLO 205.	Cellular signalling 20050201
alpha1A- but not alpha1B-adrenergic receptors precondition the ischemic heart by a staurosporine-sensitive, chelerythrine-insensitive mechanism.	Cardiovascular research 20050201
Synergistic stimulatory effect of 12-O-tetradecanoylphorbol-13-acetate and capsaicin on macrophage differentiation in HL-60 and HL-525 human myeloid leukemia cells.	International journal of oncology 20050201
Insulin-induced phosphorylation of ENaC correlates with increased sodium channel function in A6 cells.	American journal of physiology. Cell physiology 20050101
An oxidative stress mechanism mediates chelerythrine-induced heparin-binding EGF-like growth factor ectodomain shedding.	Journal of cellular biochemistry 20050101
Deferoxamine induces prolonged cardiac preconditioning via accumulation of oxygen radicals.	Free radical biology & medicine 20050101
Synthesis of oxychelerythrine using lithiated toluamide-benzonitrile cycloaddition.	Chemical & pharmaceutical bulletin 20050101
Protective effects of insulin during ischemia-reperfusion injury in hamster cheek pouch microcirculation.	Journal of vascular research 20050101
Secretion of ATP from Schwann cells in response to uridine triphosphate.	The European journal of neuroscience 20050101
Effect of pravastatin on impaired endothelium-dependent relaxation induced by lysophosphatidylcholine in rat aorta.	Acta pharmacologica Sinica 20050101
Diazoxide ameliorates microcirculatory disturbances through PKC-dependent pathway in I/R-injured rat cremaster muscles.	Journal of biomedical science 20050101
Roles of protein kinase C and fructose in hepatic injury caused by obstructive jaundice.	Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20050101
Metabolic arrest and its regulation in anoxic eel hepatocytes.	Physiological and biochemical zoology : PBZ 20050101
Effects of angiotensin II on the pericyte-containing microvasculature of the rat retina.	The Journal of physiology 20041215
Hypoxic pulmonary vasoconstriction and pulmonary artery tissue cytokine expression are mediated by protein kinase C.	American journal of physiology. Lung cellular and molecular physiology 20041201
Dual concentration-dependent effects of phorbol 12, 13-dibutyrate on spontaneous and acetylcholine-induced electrical responses recorded from isolated circular smooth muscle of the guinea-pig stomach antrum.	Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20041201
Silent information regulator 2alpha, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes.	Circulation research 20041112
Bmx, a member of the Tec family of nonreceptor tyrosine kinases, is a novel participant in pharmacological cardioprotection.	American journal of physiology. Heart and circulatory physiology 20041101
Spontaneous activity and its cholinergic modulation in circular smooth muscle isolated from guinea-pig stomach antrum.	Pflugers Archiv : European journal of physiology 20041101
Extracellular signal-regulated kinase (ERK) in glucose-induced and endothelin-mediated fibronectin synthesis.	Laboratory investigation; a journal of technical methods and pathology 20041101
Protein kinase C inhibitors produce mitochondrial flavoprotein oxidation in cardiac myocytes.	Anesthesia and analgesia 20041101
17beta-estradiol reduces the effect of metabolic inhibition on gap junction intercellular communication in rat cardiomyocytes via the estrogen receptor.	Journal of molecular and cellular cardiology 20041101
Chronic exercise improves myocardial inotropic reserve capacity through alpha1-adrenergic and protein kinase C-dependent effects in Senescent rats.	The journals of gerontology. Series A, Biological sciences and medical sciences 20041101
Down-regulation of connexin43 in early myocardial ischemia and protective effect by ischemic preconditioning in rat hearts in vivo.	Japanese heart journal 20041101
Endothelin-1 enhances the activity of Na+/Ca2+ exchanger type 1 in renal epithelial cells.	Journal of cardiovascular pharmacology 20041101
Differential interplay between protein kinase C and Rho-kinase in the endothelin-1-induced and pressure-induced contractions of rat posterior cerebral artery.	Journal of cardiovascular pharmacology 20041101
Protein kinase C overactivity impairs prefrontal cortical regulation of working memory.	Science (New York, N.Y.) 20041029
Gene therapy of endothelial nitric oxide synthase and manganese superoxide dismutase restores delayed wound healing in type 1 diabetic mice.	Circulation 20041019
Intermittent hypoxia protects the rat heart against ischemia/reperfusion injury by activating protein kinase C.	Life sciences 20041008
Aggregation and other intermolecular interactions of biological buffers observed by capillary electrophoresis and UV photometry.	Journal of chromatography. A 20041008
Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels.	Circulation research 20041001
Activation of protein kinase C contributes to the isoflurane-induced improvement of functional and metabolic recovery in isolated ischemic rat hearts.	Anesthesia and analgesia 20041001
Arg-vasopressin increases proliferation of human osteoblast-like cells and decreases production of interleukin-6 and macrophage colony-stimulating factor.	Regulatory peptides 20040915
Regulation of tumor necrosis factor-alpha in glioma cells by lead and lipopolysaccharide: involvement of common signaling pathway.	Toxicology letters 20040910
Effect of protein kinase C blockade on phosphorylation of NR1 in dorsal horn and spinothalamic tract cells caused by intradermal capsaicin injection in rats.	Brain research 20040910
Systemic regulation of vascular NAD(P)H oxidase activity and nox isoform expression in human arteries and veins.	Arteriosclerosis, thrombosis, and vascular biology 20040901
Investigation of signaling pathways that mediate the inotropic effect of urotensin-II in human heart.	Cardiovascular research 20040901
Role of protein kinase C in the excitatory action of cholinergic nerve stimulation on spontaneous activity of circular smooth muscle isolated from the guinea-pig stomach antrum.	Pflugers Archiv : European journal of physiology 20040901
Effects of alpha1-adrenergic stimulation on normal and hypertrophied mouse hearts. Relation to caveolin-3 expression.	Cardiovascular research 20040815
Role of PKCalpha and PKCiota in phenylephrine-induced contraction of rat corpora cavernosa.	International journal of impotence research 20040801
Substance P induces inward current and regulates pacemaker currents through tachykinin NK1 receptor in cultured interstitial cells of Cajal of murine small intestine.	European journal of pharmacology 20040708
Chelerythrine and other benzophenanthridine alkaloids block the human P2X7 receptor.	British journal of pharmacology 20040701
Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system.	The American journal of pathology 20040701
IgA immune complex blunts the contraction of cultured mesangial cells through the inhibition of protein kinase C and intracellular calcium.	The Chinese journal of physiology 20040630
Endothelial dysfunction in aortic rings and mesenteric beds isolated from deoxycorticosterone acetate hypertensive rats: possible involvement of protein kinase C.	European journal of pharmacology 20040628
Capillary electrophoretic studies of acid-base properties of sanguinarine and chelerythrine alkaloids.	Journal of chromatography. A 20040618
Experimental evidence for the limiting role of enzymatic reactions in chemoattractant-induced pseudopod extension in human neutrophils.	The Journal of biological chemistry 20040604
Transient glucose deprivation causes upregulation of heme oxygenase-1 and cyclooxygenase-2 expression in cardiac fibroblasts.	Journal of molecular and cellular cardiology 20040601
Mechanisms involved in carbachol-induced Ca(2+) sensitization of contractile elements in rat proximal and distal colon.	British journal of pharmacology 20040601
Cytoskeletal restraints regulate homotypic ALCAM-mediated adhesion through PKCalpha independently of Rho-like GTPases.	Journal of cell science 20040601
Regulation of proangiogenic factor CCN1 in cardiac muscle: impact of ischemia, pressure overload, and neurohumoral activation.	Circulation 20040511
Involvement of protein kinase C-related anti-apoptosis signaling in radiation-induced apoptosis in murine thymic lymphoma(3SBH5) cells.	Radiation research 20040501
Rapid change of glucose concentration promotes mesangial cell proliferation via VEGF: inhibitory effects of thiazolidinedione.	Biochemical and biophysical research communications 20040423
Epidermal growth factor induces fibroblast contractility and motility via a protein kinase C delta-dependent pathway.	The Journal of biological chemistry 20040409
Protein kinase C plays an essential role in sildenafil-induced cardioprotection in rabbits.	American journal of physiology. Heart and circulatory physiology 20040401
Hypoxia selection of death-resistant cells. A role for Bcl-X(L).	The Journal of biological chemistry 20040305
Exocytosis of a complement component C3-like protein by tunicate hemocytes.	Developmental and comparative immunology 20040301
Opioid-mediated modulation of calcium currents in striatal and pallidal neurons following reserpine treatment: focus on kappa response.	Synapse (New York, N.Y.) 20040301
Delayed preconditioning of the human myocardium: signal transduction and clinical implications.	Cardiovascular research 20040215
Hypoxia increases calcium flux through cortical neuron glutamate receptors via protein kinase C.	Journal of neurochemistry 20040201
Troglitazone acts by PPARgamma and PPARgamma-independent pathways on LLC-PK1-F+ acid-base metabolism.	American journal of physiology. Renal physiology 20040101
Sanguinarine and chelerythrine: assessment of safety on pigs in ninety days feeding experiment.	Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040101
CD3 receptor modulation in Jurkat leukemic cell line.	Folia histochemica et cytobiologica 20040101
Chelerythrine stimulates GSH transport by rat Mrp2 (Abcc2) expressed in canine kidney cells.	American journal of physiology. Gastrointestinal and liver physiology 20031201
Mechanisms of myocardial ischemic preconditioning are age related: PKC-epsilon does not play a requisite role in old rabbits.	Journal of applied physiology (Bethesda, Md. : 1985) 20031201
Nicotinic receptor-mediated regulation of the dopamine transporter in rat prefrontocortical slices following chronic in vivo administration of nicotine.	Schizophrenia research 20031201
Influence of alpha2-autoreceptor stimulation on the facilitation by angiotensin II and bradykinin of noradrenaline release.	Naunyn-Schmiedeberg's archives of pharmacology 20031201
Insulin-induced improvement of postischemic recovery is abolished by inhibition of protein kinase C in rat heart.	The Journal of thoracic and cardiovascular surgery 20031201
Converting enzyme inhibitor temocaprilat prevents high glucose-mediated suppression of human aortic endothelial cell proliferation.	Journal of cardiovascular pharmacology 20031201
Isoform-selectivity of PKC inhibitors acting at the regulatory and catalytic domain of mammalian PKC-alpha, -betaI, -delta, -eta and -zeta.	Journal of enzyme inhibition and medicinal chemistry 20031201
Electrophoretic investigation of interactions of sanguinarine and chelerythrine with molecules containing mercapto group.	Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031125
The effects of protein kinase C activity on synaptic transmission in two areas of rat hippocampus.	Brain research 20031114
Constitutive cytoplasmic localization of p21(Waf1/Cip1) affects the apoptotic process in monocytic leukaemia.	Leukemia 20031101
Immunocytochemical detection of GLUT2 at the rat intestinal brush-border membrane.	The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20031101
Cellular redistribution of inducible Hsp70 protein in the human and rabbit heart in response to the stress of chronic hypoxia: role of protein kinases,	The Journal of biological chemistry 20031031
Signaling via histamine receptors in cat duodenal smooth muscle cells.	Molecules and cells 20031031
Involvement of protein kinase C in the adaptive changes of cholinergic neurons to sympathetic denervation in the guinea pig myenteric plexus.	Life sciences 20031003
Endothelin-1 limits vascular smooth muscle beta-adrenergic receptor sensitivity by a PKC-dependent pathway.	Journal of cardiovascular pharmacology 20031001
HL-1 myocytes exhibit PKC and K(ATP) channel-dependent delta opioid preconditioning.	The Journal of surgical research 20031001
Protein kinase C inhibition induces DNA fragmentation in COLO 205 cells which is blocked by cysteine protease inhibition but not mediated through caspase-3.	Experimental cell research 20030910
Kinase-dependent loss of Na+ channel slow-inactivation in rat CA1 hippocampal pyramidal cell dendrites after brief exposure to convulsants.	The European journal of neuroscience 20030901
Signaling pathway for aloe-emodin-induced apoptosis in human H460 lung nonsmall carcinoma cell.	International journal of cancer 20030810
Protein kinase C modifications of VE-cadherin, p120, and beta-catenin contribute to endothelial barrier dysregulation induced by thrombin.	American journal of physiology. Lung cellular and molecular physiology 20030801
Chelerythrin activates caspase-8, downregulates FLIP long and short, and overcomes resistance to tumour necrosis factor-related apoptosis-inducing ligand in KG1a cells.	British journal of haematology 20030801
Human beta(3)-adrenoreceptors couple to KvLQT1/MinK potassium channels in Xenopus oocytes via protein kinase C phosphorylation of the KvLQT1 protein.	Naunyn-Schmiedeberg's archives of pharmacology 20030801
Diverse regulation of atrial natriuretic peptide secretion by serotonin receptor subtypes.	Cardiovascular research 20030801
Inhibition of alpha, betaI, delta, eta, and zeta protein kinase C isoforms by xanthonolignoids.	Journal of enzyme inhibition and medicinal chemistry 20030801
Co-stimulation of mGluR5 and N-methyl-D-aspartate receptors is required for potentiation of excitatory synaptic transmission in hippocampal neurons.	The Journal of biological chemistry 20030725
Alpha-2 adrenoceptor mediating the facilitatory effect of norepinephrine on the glycine response in the spinal dorsal horn neuron of the rat.	Life sciences 20030704
Protein kinase C-delta mediates adenosine A3 receptor-induced delayed cardioprotection in mouse.	American journal of physiology. Heart and circulatory physiology 20030701
Role of protein kinase C in geranylgeranylacetone-induced expression of heat-shock protein 72 and cardioprotection in the rat heart.	Journal of molecular and cellular cardiology 20030701
Various inotropic effects of angiotensin II in post-ischaemic rat hearts depending on ischaemic time with possible involvement of protein kinase C.	Acta physiologica Scandinavica 20030701
Inhibition of taurine transport by high concentration of glucose in cultured rat cardiomyocytes.	Metabolism: clinical and experimental 20030701
A double-lumen intrathecal catheter for studies of modulation of spinal opiate tolerance.	Journal of neuroscience methods 20030630
Ischaemic tolerance in aged mouse myocardium: the role of adenosine and effects of A1 adenosine receptor overexpression.	The Journal of physiology 20030615
Identification of chelerythrine as an inhibitor of BclXL function.	The Journal of biological chemistry 20030606
Differential regulation of early growth response gene-1 expression by insulin and glucose in vascular endothelial cells.	Arteriosclerosis, thrombosis, and vascular biology 20030601
Adenosine-mediated early preconditioning in mouse: protective signaling and concentration dependent effects.	Cardiovascular research 20030601
Preischemic infusion of alpha-human atrial natriuretic peptide elicits myoprotective effects against ischemia reperfusion in isolated rat hearts.	Molecular and cellular biochemistry 20030601
Differential activation of protein kinase C between ischemic and pharmacological preconditioning in the rabbit heart.	The Japanese journal of physiology 20030601
PKC is required for activation of ROCK by RhoA in human endothelial cells.	Biochemical and biophysical research communications 20030516
Properties of a constitutively active Ca2+-permeable non-selective cation channel in rabbit ear artery myocytes.	The Journal of physiology 20030515
Activation of Mst1 causes dilated cardiomyopathy by stimulating apoptosis without compensatory ventricular myocyte hypertrophy.	The Journal of clinical investigation 20030515
Reactive oxygen species are involved in smoking-induced dysfunction of nitric oxide biosynthesis and upregulation of endothelial nitric oxide synthase: an in vitro demonstration in human coronary artery endothelial cells.	Circulation 20030513
Protein kinase C activation generates superoxide and contributes to impairment of cerebrovasodilation induced by G protein activation after brain injury.	Brain research 20030509
Norepinephrine evoked by potassium depolarization increases interstitial adenosine concentration via activation of ecto-5'-nucleotidase in rat hearts.	The Journal of pharmacology and experimental therapeutics 20030501
Modulation of protein kinase C (PKC)-mediated contraction and the possible role of PKC epsilon in rat mesenteric arteries.	Frontiers in bioscience : a journal and virtual library 20030501
Tyrosine kinase is involved in hemin-induced pyresis.	Archives of pharmacal research 20030501
Chelerythrine and bisindolylmaleimide I prolong cardiac action potentials by protein kinase C-independent mechanism.	European journal of pharmacology 20030411
Inhibition of protein kinase C by synthetic xanthone derivatives.	Bioorganic & medicinal chemistry 20030403
Dopaminergic inhibition of secretin-stimulated choleresis by increased PKC-gamma expression and decrease of PKA activity.	American journal of physiology. Gastrointestinal and liver physiology 20030401
Phosphorylation of protein kinase C sites in NBD1 and the R domain control CFTR channel activation by PKA.	The Journal of physiology 20030401
Control of head morphogenesis in an invertebrate asexually produced larva-like bud ( Cassiopea andromeda; Cnidaria: Scyphozoa).	Development genes and evolution 20030401
The induction of heat shock protein-72 attenuates cisplatin-induced acute renal failure in rats.	Pflugers Archiv : European journal of physiology 20030401
Vasospasm following subarachnoid hemorrhage: evidence against functional upregulation of protein kinase C constrictor pathway.	Neurological research 20030401
Effect of protein kinase C activation and inhibition on rat hepatic stellate cell activation.	Digestive diseases and sciences 20030401
Lipoxin A4 stimulates a cytosolic Ca2+ increase in human bronchial epithelium.	The Journal of biological chemistry 20030328
Vitamin E deficiency reduces surfactant lipid biosynthesis in alveolar type II cells.	Free radical biology & medicine 20030315
Effects of a phorbol ester and cyclosporin A on hippocampal synaptic plasticity in streptozotocin-induced-diabetic rats: reduced sensitivity to phorbol esters.	Neuroscience letters 20030313
[Effects of chelerythrine on cell proliferation and p27 expression of cardiac fibroblasts modulated by arginine vasopressin].	Zhonghua yi xue za zhi 20030310
D-2-amino-5-phosphonopentanoic acid inhibits intrathecal pertussis toxin-induced thermal hyperalgesia and protein kinase Cgamma up-regulation.	Brain research 20030214
The effect of chelerythrine on depolarization-induced force responses in skinned fast skeletal muscle fibres of the rat.	British journal of pharmacology 20030201
Potentiation of glycine responses by dideoxyforskolin and tamoxifen in rat spinal neurons.	The European journal of neuroscience 20030201
PMA decreases the proliferation of retinal cells in vitro: the involvement of acetylcholine and BDNF.	Neurochemistry international 20030101
Natriuretic peptides suppress protein kinase C activity to reduce evoked dopamine efflux from pheochromocytoma (PC12) cells.	Endocrinology 20030101
Role of protein kinase C in central muscarinic inhibitory mechanisms regulating voiding in rats.	Neuroscience 20030101
A calcium/calmodulin kinase pathway connects brain-derived neurotrophic factor to the cyclic AMP-responsive transcription factor in the rat hippocampus.	Neuroscience 20030101
Protein kinase C is involved in clozapine's facilitation of N-methyl-D-aspartate- and electrically evoked responses in pyramidal cells of the medial prefrontal cortex.	Neuroscience 20030101
Adenosine suppresses the response of neurons to gaba in the superficial laminae of the rat spinal dorsal horn.	Neuroscience 20030101
Quaternary benzo[c]phenanthridine alkaloids as inhibitors of dipeptidyl peptidase IV-like activity baring enzymes in human blood plasma and glioma cell lines.	Physiological research 20030101
Attenuation of canine cerebral vasospasm after subarachnoid hemorrhage by protein kinase C inhibitors despite augmented phosphorylation of myosin light chain.	Journal of vascular research 20030101
Pituitary adenylate cyclase-activating polypeptide (PACAP)-evoked increase in cyclic AMP production in chick cerebral cortex: lack of a role of the protein kinase C pathway.	Polish journal of pharmacology 20030101
Modulation of CD40L antigen expression in Jurkat cells: involvement of protein kinase C activity.	Folia histochemica et cytobiologica 20030101
[Effect of inhibiting protein kinase C on calcium sensitivity of contractile apparatus of vascular smooth muscle during vasospasms of different origins].	Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20030101
Differential regulation by Ca(2+) of calmodulin- and PKC-dependent contractile pathways in cat lower oesophageal sphincter.	Autonomic & autacoid pharmacology 20030101
The intracellular pathway of the acetylcholine-induced contraction in cat detrusor muscle cells.	British journal of pharmacology 20021201
Differential mechanisms of morphine antinociceptive tolerance revealed in (beta)arrestin-2 knock-out mice.	The Journal of neuroscience : the official journal of the Society for Neuroscience 20021201
Involvement of 5-HT7 receptors in serotonergic effects on spike afterpotentials in presumed jaw-closing motoneurons of rats.	Brain research 20021108
Phorbol ester stimulates a protein kinase C-mediated agatoxin-TK-sensitive calcium permeability pathway in human red blood cells.	Blood 20021101
Upregulation of myocardial Na+/H+ exchanger induced by chronic treatment with a selective inhibitor.	Journal of molecular and cellular cardiology 20021101
Neurotensin modulates the amplitude and frequency of voltage-activated Ca2+ currents in frog pituitary melanotrophs: implication of the inositol triphosphate/protein kinase C pathway.	The European journal of neuroscience 20021101
Modulation of steroid hydroxylase activity in stably transfected V79MZh11B1 and V79MZh11B2 cells by PKC and PKD inhibitors.	Endocrine research 20021101
Factors contributing to neurotrophin-independent survival of adult sensory neurons.	Brain research 20021025
Interaction between alpha2-autoreceptors and receptors mediating the effects of angiotensin II and bradykinin in the heart of newborn rats.	European journal of pharmacology 20021025
Protein kinase C activation induces phosphatidylserine exposure on red blood cells.	Biochemistry 20021015
Regulation of mdm2 mRNA expression in human breast tumor-derived GI-101A cells.	Life sciences 20021004
The role of serotonin in ischemic cellular damage and the infarct size-reducing effect of sarpogrelate, a 5-hydroxytryptamine-2 receptor blocker, in rabbit hearts.	Journal of the American College of Cardiology 20021002
Different signal transduction pathways are involved during human sperm capacitation induced by biological and pharmacological agents.	Molecular human reproduction 20020901
Regulation of NFkappaB in hepatic ischemic preconditioning.	Journal of the American College of Surgeons 20020901
Inhibitory activity on binding of specific ligands to the human angiotensin II AT(1) and endothelin 1 ET(A) receptors: bioactive benzo[c]phenanthridine alkaloids from the root of Bocconia frutescens.	Planta medica 20020901
Activation of glutamate receptors inhibits Na/K-ATPase of cerebellum granule cells.	Biochemistry. Biokhimiia 20020901
Intestinal ischemia preconditions myocardium: role of protein kinase C and mitochondrial K(ATP) channel.	Cardiovascular research 20020815
Remote preconditioning protects the heart by activating myocardial PKCepsilon-isoform.	Cardiovascular research 20020815
Excitation of smooth muscles isolated from the guinea-pig gastric antrum in response to depolarization.	The Journal of physiology 20020815
DNA adduct formation from quaternary benzo[c]phenanthridine alkaloids sanguinarine and chelerythrine as revealed by the 32P-postlabeling technique.	Chemico-biological interactions 20020815
Two kinase activities are sufficient for sea urchin sperm chromatin decondensation in vitro.	Molecular reproduction and development 20020801
Orphanin FQ/nociceptin-mediated desensitization of opioid receptor-like 1 receptor and mu opioid receptors involves protein kinase C: a molecular mechanism for heterologous cross-talk.	The Journal of pharmacology and experimental therapeutics 20020801
Modulation of volume-sensitive chloride current by noradrenaline in rabbit portal vein myocytes.	The Journal of physiology 20020715
Moderate alcohol consumption induces sustained cardiac protection by activating PKC-epsilon and Akt.	American journal of physiology. Heart and circulatory physiology 20020701
ATP-inhibition of M current in frog sympathetic neurons involves phospholipase C but not Ins P(3), Ca(2+), PKC, or Ras.	Journal of neurophysiology 20020701
Cardioprotection mediated by sphingosine-1-phosphate and ganglioside GM-1 in wild-type and PKC epsilon knockout mouse hearts.	American journal of physiology. Heart and circulatory physiology 20020601
alpha-Adrenergic response and myofilament activity in mouse hearts lacking PKC phosphorylation sites on cardiac TnI.	American journal of physiology. Heart and circulatory physiology 20020601
Dopamine-induced inhibition of Na+-K+-ATPase activity requires integrity of actin cytoskeleton in opossum kidney cells.	Acta physiologica Scandinavica 20020601
Protein kinase C modulators enhance angiotensin II desensitization of guinea pig ileum via maxi-K+ channels.	European journal of pharmacology 20020503
Inhibition of cAMP accumulation by kappa-receptor activation in isolated iris-ciliary bodies: role of phosphodiesterase and protein kinase C.	The Journal of pharmacology and experimental therapeutics 20020501
Angiotensin II increases L-type Ca2+ current in gramicidin D-perforated adult rabbit ventricular myocytes: comparison with conventional patch-clamp method.	Pflugers Archiv : European journal of physiology 20020501
Dual regulation of cardiac Na+-K+ pumps and CFTR Cl- channels by protein kinases A and C.	Pflugers Archiv : European journal of physiology 20020501
Antagonists of protein kinase C inhibit rat retinal glutamate transport activity in situ.	Journal of neurochemistry 20020501
Uptake of (3)H-1-methyl-4-phenylpyridinium ((3)H-MPP(+)) by human intestinal Caco-2 cells is regulated by phosphorylation/dephosphorylation mechanisms.	Biochemical pharmacology 20020415
Preconditioning blocks cardiocyte apoptosis: role of K(ATP) channels and PKC-epsilon.	American journal of physiology. Heart and circulatory physiology 20020401
Role of protein kinase C in control of ethanol-modulated beta-endorphin release from hypothalamic neurons in primary cultures.	The Journal of pharmacology and experimental therapeutics 20020401
Protein kinase Mzeta is necessary and sufficient for LTP maintenance.	Nature neuroscience 20020401
Memory enhancement and formation by atypical PKM activity in Drosophila melanogaster.	Nature neuroscience 20020401
Voltage independence of vasomotion in isolated irideal arterioles of the rat.	The Journal of physiology 20020401
Role of protein kinase C-epsilon in the development of kappa-opioid receptor tolerance to U50,488H in rat ventricular myocytes.	British journal of pharmacology 20020401
Ethanol alters glutamate but not adenosine uptake in rat astrocytes: evidence for protein kinase C involvement.	Neurochemical research 20020401
Effect of modulators of protein kinase C activity on Ca2+ transport in retinal rod microsomes.	Biochemistry. Biokhimiia 20020401
Protective effects of protein kinase C during myocardial ischemia require activation of phosphatidyl-inositol specific phospholipase C.	The Annals of thoracic surgery 20020401
Human urotensin II-induced aorta ring contractions are mediated by protein kinase C, tyrosine kinases and Rho-kinase: inhibition by somatostatin receptor antagonists.	European journal of pharmacology 20020308
Endothelin-induced changes in the physiology of retinal pericytes.	Investigative ophthalmology & visual science 20020301
Effects of fasting on corticosterone production by zona fasciculata-reticularis cells in ovariectomized rats.	Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20020301
Roles of protein kinase C and alpha-tocopherol in regulation of signal transduction for GATA-4 phosphorylation in HL-1 cardiac muscle cells.	Free radical biology & medicine 20020215
Diverse inhibitors of intracellular signalling act as adenosine receptor antagonists.	Cellular signalling 20020201
Altered PYK2 phosphorylation by ANG II in hypertensive vascular smooth muscle.	American journal of physiology. Heart and circulatory physiology 20020201

Deoxycholic acid inhibits smooth muscle contraction via protein kinase C-dependent modulation of L-type Ca2+ channels in rat proximal colon.

Molecular medicine reports 20121001

Regulation of estradiol and progesterone production by CRH-R1 and -R2 is through divergent signaling pathways in cultured human placental trophoblasts.

Endocrinology 20121001

Involvement of basal and calcium-activated protein kinase C in neurotransmitter secretion in mouse motor synapses.

Bulletin of experimental biology and medicine 20121001

Luminescence and binding properties of two isoquinoline alkaloids chelerythrine and sanguinarine with ctDNA.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120901

Exercise preconditioning provides early cardioprotection against exhaustive exercise in rats: potential involvement of protein kinase C delta translocation.

Molecular and cellular biochemistry 20120901

Task demands dissociate the effects of muscarinic M1 receptor blockade and protein kinase C inhibition on attentional performance in rats.

Journal of psychopharmacology (Oxford, England) 20120801

[Effect of intrathecal sufentanil and protein kinase C inhibitor on pain threshold and the expression of NMDA receptor/ CGRP in spinal dorsal horn in rats with neuropathic pain].

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20120801

Facilitation of neurotransmitter release in mouse motor synapses in different modes of protein kinase C activation.

Bulletin of experimental biology and medicine 20120801

Investigation of sanguinarine and chelerythrine effects on LPS-induced inflammatory gene expression in THP-1 cell line.

Phytomedicine : international journal of phytotherapy and phytopharmacology 20120715

Protein kinase C inhibitor prevents renal apoptotic and fibrotic changes in response to partial ureteric obstruction.

BJU international 20120701

Protein kinase C-α mediates hypertonicity-stimulated increase in urea transporter phosphorylation in the inner medullary collecting duct.

American journal of physiology. Renal physiology 20120501

Differential consequences of protein kinase C activation during early and late hepatic ischemic preconditioning.

The journal of physiological sciences : JPS 20120501

Cardioprotection of electroacupuncture against myocardial ischemia-reperfusion injury by modulation of cardiac norepinephrine release.

American journal of physiology. Heart and circulatory physiology 20120501

Protective effect of urantide against ischemia-reperfusion injury via protein kinase C and phosphtidylinositol 3'-kinase - Akt pathway.

Canadian journal of physiology and pharmacology 20120501

Protein kinase mζ is necessary for cocaine-induced synaptic potentiation in the ventral tegmental area.

Biological psychiatry 20120415

Cellular pharmacology of protein kinase Mζ (PKMζ) contrasts with its in vitro profile: implications for PKMζ as a mediator of memory.

The Journal of biological chemistry 20120413

Testosterone modulates platelet aggregation and endothelial cell growth through nitric oxide pathway.

The Journal of endocrinology 20120401

Fluvoxamine increased glutamate release by activating both 5-HT(3) and sigma-1 receptors in prelimbic cortex of chronic restraint stress C57BL/6 mice.

Biochimica et biophysica acta 20120401

Transient Ca2+ mobilization caused by osmotic shock initiates salmonid fish sperm motility.

The Journal of experimental biology 20120215

Role of stored calcium in the regulation of neurotransmitter quantum size.

Bulletin of experimental biology and medicine 20120201

Melatonin elicits protein kinase C-mediated calcium response in immortalized GT1-7 GnRH neurons.

Brain research 20120130

One-pot synthesis of isoquinolinium salts by rhodium-catalyzed C-H bond activation: application to the total synthesis of oxychelerythrine.

Angewandte Chemie (International ed. in English) 20120102

Physiological effect of protein kinase C on ENaC-mediated lung liquid regulation in the adult rat lung.

American journal of physiology. Lung cellular and molecular physiology 20120101

The proton-activated G protein coupled receptor OGR1 acutely regulates the activity of epithelial proton transport proteins.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101

Pharmacological differences of endothelin receptors-mediated modulation in cultured interstitial cells of Cajal from the murine small and large intestine.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101

Neuromedin S increases L-type Ca(2+) channel currents through G(i)α-protein and phospholipase C-dependent novel protein kinase C delta pathway in adult rat ventricular myocytes.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101

Reactive oxygen species-independent rapid initiation of mitochondrial apoptotic pathway by chelerythrine.

Toxicology in vitro : an international journal published in association with BIBRA 20111201

Formulation optimization of chelerythrine loaded O-carboxymethylchitosan microspheres using response surface methodology.

International journal of biological macromolecules 20111201

The ERM protein, ezrin, regulates neutrophil transmigration by modulating the apical localization of MRP2 in response to the SipA effector protein during Salmonella Typhimurium infection.

Cellular microbiology 20111201

Platelet-activating factor stimulates sodium-hydrogen exchange in ventricular myocytes.

American journal of physiology. Heart and circulatory physiology 20111201

KMUP-1 inhibits L-type Ca²⁺ channels involved the protein kinase C in rat basilar artery myocytes.

The Kaohsiung journal of medical sciences 20111201

Tumor necrosis factor-α downregulates sodium current in skeletal muscle by protein kinase C activation: involvement in critical illness polyneuromyopathy.

American journal of physiology. Cell physiology 20111101

Parathyroid hormone and the regulation of cell cycle in colon adenocarcinoma cells.

Biochimica et biophysica acta 20111001

Neurotensin inhibits background K+ channels and facilitates glutamatergic transmission in rat spinal cord dorsal horn.

The European journal of neuroscience 20111001

Rat lymphocytes express NMDA receptors that take part in regulation of cytokine production.

Cell biochemistry and function 20111001

β₁-adrenergic receptor up-regulation induced by nadolol is mediated via signal transduction pathway coupled to α₁-adrenergic receptors.

Brain research 20110926

Agonist-induced periodic vasomotion in rat isolated pulmonary artery.

Fundamental & clinical pharmacology 20110801

Activity of the chelerythrine, a quaternary benzo[c]phenanthridine alkaloid from Chelidonium majus L. on Dactylogyrus intermedius.

Parasitology research 20110701

Thyroid hormones modulate GABA(A) receptor-mediated currents in hippocampal neurons.

Neuropharmacology 20110601

Effects of chelerythrine, a specific inhibitor of cyclooxygenase-2, on acute inflammation in mice.

Fitoterapia 20110601

PKCgamma in Vc and C1/C2 is involved in trigeminal neuropathic pain.

Journal of dental research 20110601

Protein kinase C phosphorylates the cAMP response element binding protein in the hypothalamic paraventricular nucleus during morphine withdrawal.

British journal of pharmacology 20110601

Chelerythrine perturbs lamellar actomyosin filaments by selective inhibition of myotonic dystrophy kinase-related Cdc42-binding kinase.

FEBS letters 20110506

Antidepressant phenotype by inhibiting the phospholipase Cβ(1)--protein kinase Cγ pathway in the forced swim test.

Neuropharmacology 20110501

Differential effect of the benzophenanthridine alkaloids sanguinarine and chelerythrine on glycine transporters.

Neurochemistry international 20110501

The heart: a novel gonadotrophin-releasing hormone target.

Journal of neuroendocrinology 20110501

Identification of benzo[c]phenanthridine metabolites in human hepatocytes by liquid chromatography with electrospray ion-trap and quadrupole time-of-flight mass spectrometry.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110501

Structural modification of sanguinarine and chelerythrine and their antibacterial activity.

Natural product research 20110501

Induction of apoptosis by chelerythrine chloride through mitochondrial pathway and Bcl-2 family proteins in human hepatoma SMMC-7721 cell.

Archives of pharmacal research 20110501

Protein kinase M maintains long-term sensitization and long-term facilitation in aplysia.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20110427

Microarray analysis of the chelerythrine-induced transcriptome of Mycobacterium tuberculosis.

Current microbiology 20110401

Hypoxia-induced sensitization of transient receptor potential vanilloid 1 involves activation of hypoxia-inducible factor-1 alpha and PKC.

Pain 20110401

Kisspeptin-10 elicits triphasic cytosolic calcium responses in immortalized GT1-7 GnRH neurones.

Neuroscience letters 20110329

A phospholipase A₂ isolated from Lachesis muta snake venom increases the survival of retinal ganglion cells in vitro.

Toxicon : official journal of the International Society on Toxinology 20110315

The actions of benzophenanthridine alkaloids, piperonyl butoxide and (S)-methoprene at the G-protein coupled cannabinoid CB₁ receptor in vitro.

European journal of pharmacology 20110301

Luteinizing hormone (LH) acts through PKA and PKC to modulate T-type calcium currents and intracellular calcium transients in mice Leydig cells.

Cell calcium 20110301

Effects of the PKC inhibitors chelerythrine and bisindolylmaleimide I (GF 109203X) on delayed rectifier K+ currents.

Naunyn-Schmiedeberg's archives of pharmacology 20110201

Characteristics of myogenic reactivity in isolated rat mesenteric veins.

American journal of physiology. Regulatory, integrative and comparative physiology 20110201

Protein kinase C modulates NMDA receptors in the myenteric plexus of the guinea pig ileum during in vitro ischemia and reperfusion.

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20110201

Morphine postconditioning attenuates ICAM-1 expression on endothelial cells.

Journal of Korean medical science 20110201

Mechanism governing reversal of multidrug resistance in human breast carcinoma cells by chelerythrine.

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20110201

Fos expression induced by activation of NMDA and neurokinin-1 receptors in the trigeminal subnucleus caudalis in vitro: role of protein kinases.

Brain research 20110112

Exercise preconditioning initiates late cardioprotection against isoproterenol-induced myocardial injury in rats independent of protein kinase C.

The journal of physiological sciences : JPS 20110101

L-type calcium channel β subunit modulates angiotensin II responses in cardiomyocytes.

Channels (Austin, Tex.) 20110101

Short-duration therapeutic hypothermia causes prompt connexin43 gap junction remodeling in isolated rabbit hearts.

Circulation journal : official journal of the Japanese Circulation Society 20110101

[Effect of vasopressin on the membrane potential of rat hepatocytes].

Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20110101

AT₁ receptor and NAD(P)H oxidase mediate angiotensin II-stimulated antioxidant enzymes and mitogen-activated protein kinase activity in the rat hypothalamus.

Journal of the renin-angiotensin-aldosterone system : JRAAS 20101201

Protein kinase C regulates urea permeability in the rat inner medullary collecting duct.

American journal of physiology. Renal physiology 20101201

Protein kinase C activation modulates reversible increase in cortical blood-brain barrier permeability and tight junction protein expression during hypoxia and posthypoxic reoxygenation.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20101101

TRPC6 channels stimulated by angiotensin II are inhibited by TRPC1/C5 channel activity through a Ca2+- and PKC-dependent mechanism in native vascular myocytes.

The Journal of physiology 20101001

Opioid peptide deltorphin II simulates the cardioprotective effect of ischemic preconditioning: role of δ₂-opioid receptors, protein kinase C, and K(ATP) channels.

Bulletin of experimental biology and medicine 20101001

Role of protein kinase Czeta in thrombin-induced RhoA activation and inter-endothelial gap formation of human dermal microvessel endothelial cell monolayers.

Microvascular research 20100901

Protein kinase A and C signaling induces bilirubin potentiation of GABA/glycinergic synaptic transmission in rat ventral cochlear nucleus neurons.

Brain research 20100812

Distinctions between persistent and reversible group I mGluR-induced epileptiform burst prolongation.

Epilepsia 20100801

[The study of effects and mechanism of U50, 488H on electrical coupling during ischemia in the perfused isolated rat heart].

Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20100801

Mechanism of inhibition of acetylcholine secretion in newly formed mouse synapses involving Ca2+-dependent kinases and voltage-gated K+-channels.

Bulletin of experimental biology and medicine 20100801

Rho kinase activation and ROS production contributes to the cooling enhanced contraction in cutaneous equine digital veins.

Journal of applied physiology (Bethesda, Md. : 1985) 20100701

Plant Natural compounds with antibacterial activity towards common pathogens of pond-cultured channel catfish (Ictalurus punctatus).

Toxins 20100701

Involvement of inositol-1,4,5-trisphosphate receptors in the bidirectional synaptic plasticity induced in hippocampal CA1 neurons by 1-10 Hz low-frequency stimulation.

Neuroscience 20100630

The identification of inhibitors of Schistosoma mansoni miracidial transformation by incorporating a medium-throughput small-molecule screen.

Experimental parasitology 20100601

Multiple kinase pathways regulate voltage-dependent Ca2+ influx and migration in oligodendrocyte precursor cells.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20100505

[Role of protein kinase C in protecting rats against pulmonary ischemia reperfusion injury through opening of mitochondrial ATP sensitive potassium channel].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20100501

Activation of muscarinic M-1 cholinoceptors by curcumin to increase contractility in urinary bladder isolated from Wistar rats.

Neuroscience letters 20100405

Role of progesterone on the regulation of vascular muscle cells proliferation, migration and apoptosis.

Steroids 20100401

Rho kinase and protein kinase C involvement in vascular smooth muscle myofilament calcium sensitization in arteries from diabetic rats.

British journal of pharmacology 20100401

[Effects of a protein kinase C inhibitor combined with cisplatin on non-small cell lung cancer].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20100401

Role of Rho-kinase in mediating contraction of chicken embryo femoral arteries.

Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20100301

Regulation of K-Cl cotransport in erythrocytes of frog Rana temporaria by commonly used protein kinase and protein phosphatase inhibitors.

Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20100301

High glucose increases expression of cyclooxygenase-2, increases oxidative stress and decreases the generation of nitric oxide in mouse microvessel endothelial cells.

Journal of cellular physiology 20100301

Critical involvement of postsynaptic protein kinase activation in long-term potentiation at hippocampal mossy fiber synapses on CA3 interneurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20100224

Attenuation of renal ischemia-reperfusion injury by postconditioning involves adenosine receptor and protein kinase C activation.

Transplant international : official journal of the European Society for Organ Transplantation 20100201

Involvement of protein kinase C-CPI-17 in androgen modulation of angiotensin II-renal vasoconstriction.

Cardiovascular research 20100201

Autophagy and protein kinase C are required for cardioprotection by sulfaphenazole.

American journal of physiology. Heart and circulatory physiology 20100201

Rift valley fever virus infection of human cells and insect hosts is promoted by protein kinase C epsilon.

PloS one 20100101

Inactivation of the Ecs ABC transporter of Staphylococcus aureus attenuates virulence by altering composition and function of bacterial wall.

PloS one 20100101

Antiproliferative and antiangiogenic effects of the benzophenanthridine alkaloid sanguinarine in melanoma.

Biochemical pharmacology 20091201

The membrane cytoskeletal protein adducin is phosphorylated by protein kinase C in D1 neurons of the nucleus accumbens and dorsal striatum following cocaine administration.

Journal of neurochemistry 20091201

PKC-permitted elevation of sarcolemmal KATP concentration may explain female-specific resistance to myocardial infarction.

The Journal of physiology 20091201

Rapid use-dependent down-regulation of gamma-aminobutyric acid type A receptors in rat mesencephalic trigeminal neurons.

Journal of neuroscience research 20091101

[Determination of chelerythrine in Chelidonium majus by RP-HPLC].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091101

Cardiac Na+ current regulation by pyridine nucleotides.

Circulation research 20091009

Cardiac metabolic state and Brugada syndrome: a link revealed.

Circulation research 20091009

Structure-activity relationship of isoform selective inhibitors of Rac1/1b GTPase nucleotide binding.

Bioorganic & medicinal chemistry letters 20091001

Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Nature chemical biology 20091001

Antifungal activity of the benzo[c]phenanthridine alkaloids from Chelidonium majus Linn against resistant clinical yeast isolates.

Journal of ethnopharmacology 20090925

Selective sigma receptor agonist 2-(4-morpholinethyl)1-phenylcyclohexanecarboxylate (PRE084) promotes neuroprotection and neurite elongation through protein kinase C (PKC) signaling on motoneurons.

Neuroscience 20090804

Effect of protease-activated receptor 2 activation on single TRPV1 channel activities in rat vagal pulmonary sensory neurons.

Experimental physiology 20090801

Ragweed pollen-mediated IgE-independent release of biogenic amines from mast cells via induction of mitochondrial dysfunction.

Molecular immunology 20090801

Regulation of store-operated Ca2+ entry in pulmonary artery smooth muscle cells.

Cell calcium 20090801

Protective mechanisms of NO preconditioning against NO-induced apoptosis in H9c2 cells: role of PKC and COX-2.

Free radical research 20090801

[Studies on chemical constituents of fructus broussonetiae].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20090801

Role of mitochondrial ATP-sensitive potassium channels on fatigue in mouse muscle fibers.

Biochemical and biophysical research communications 20090717

The anti-arrhythmic peptide AAP10 remodels Cx43 and Cx40 expression and function.

Naunyn-Schmiedeberg's archives of pharmacology 20090701

The role of nitric oxide and reactive oxygen species in the positive inotropic response to mechanical stretch in the mammalian myocardium.

Biochimica et biophysica acta 20090701

Relaxin alters cardiac myofilament function through a PKC-dependent pathway.

American journal of physiology. Heart and circulatory physiology 20090701

Delayed anti-arrhythmic effect of nitroglycerin in anesthetized rats: involvement of CGRP, PKC and mK ATP channels.

International journal of cardiology 20090626

Water taste transduction pathway is calcium dependent in Drosophila.

Chemical senses 20090601

Activation of peripheral delta2 opioid receptors increases cardiac tolerance to ischemia/reperfusion injury Involvement of protein kinase C, NO-synthase, KATP channels and the autonomic nervous system.

Life sciences 20090508

Protein kinase C activity is associated with prefrontal cortical decline in aging.

Neurobiology of aging 20090501

Direct evidence for the up-regulation of Vps34 regulated by PKCgamma during short-term treatment with morphine.

Synapse (New York, N.Y.) 20090501

A retrograde apoptotic signal originating in NGF-deprived distal axons of rat sympathetic neurons in compartmented cultures.

Cell research 20090501

Lysophosphatidic acid signaling promotes proliferation, differentiation, and cell survival in rat growth plate chondrocytes.

Biochimica et biophysica acta 20090501

CapZ dynamics are altered by endothelin-1 and phenylephrine via PIP2- and PKC-dependent mechanisms.

American journal of physiology. Cell physiology 20090501

Effects of desflurane and propofol on electrophysiological parameters during and recovery after hypoxia in rat hippocampal slice CA1 pyramidal cells.

Neuroscience 20090421

Rapid component I(Kr) of cardiac delayed rectifier potassium currents in guinea-pig is inhibited by alpha(1)-adrenoreceptor activation via protein kinase A and protein kinase C-dependent pathways.

European journal of pharmacology 20090417

Statins and fenofibrate affect skeletal muscle chloride conductance in rats by differently impairing ClC-1 channel regulation and expression.

British journal of pharmacology 20090401

Analysis of alkaloids in Macleaya cordata (Willd.) R. Br. using high-performance liquid chromatography with diode array detection and electrospray ionization mass spectrometry.

Journal of chromatography. A 20090313

Protein kinase C mediates amyloid beta-protein fragment 31-35-induced suppression of hippocampal late-phase long-term potentiation in vivo.

Neurobiology of learning and memory 20090301

Improvement of deficient natural killer activity and delayed bactericidal activity by a thiol proteinase inhibitor, E-64-d, in leukocytes from Chediak-Higashi syndrome patients in vitro.

International immunopharmacology 20090301

Role of oxidative stress in the natriuresis induced by central administration of angiotensin II.

Journal of the renin-angiotensin-aldosterone system : JRAAS 20090301

Bradykinin regulates calpain and proinflammatory signaling through TRPM7-sensitive pathways in vascular smooth muscle cells.

American journal of physiology. Regulatory, integrative and comparative physiology 20090201

Obligatory role for phosphatidylinositol 4,5-bisphosphate in activation of native TRPC1 store-operated channels in vascular myocytes.

The Journal of physiology 20090201

Effect of curcumin on acidic pH-induced expression of IL-6 and IL-8 in human esophageal epithelial cells (HET-1A): role of PKC, MAPKs, and NF-kappaB.

American journal of physiology. Gastrointestinal and liver physiology 20090201

Two PKC consensus sites on human acid-sensing ion channel 1b differentially regulate its function.

American journal of physiology. Cell physiology 20090201

Synthesis and structure-activity relationships of novel, substituted 5,6-dihydrodibenzo[a,g]quinolizinium P2X7 antagonists.

Bioorganic & medicinal chemistry letters 20090201

Contribution of RhoA kinase and protein kinase C to weak relaxant effect of pinacidil on carbachol-induced contractions in sensitized guinea-pig trachealis.

Archives of pharmacal research 20090201

[The effect of chelerythrine on the hypertrophy of cardiac myocytes of neonatal rats induced by different glucose levels and its mechanism].

Yao xue xue bao = Acta pharmaceutica Sinica 20090201

[Mechanisms of gross saponins of Tribulus terrestris via activating PKCepsilon against myocardial apoptosis induced by oxidative stress].

Yao xue xue bao = Acta pharmaceutica Sinica 20090201

Angiotensin II stimulates water and NaCl intake through separate cell signalling pathways in rats.

Experimental physiology 20090101

Structural and functional similarity between the bacterial type III secretion system needle protein PrgI and the eukaryotic apoptosis Bcl-2 proteins.

PloS one 20090101

Cholinergic excitation of dopaminergic cells depends on sequential activation of protein kinase C and the L-type calcium channel in ventral tegmental area slices.

Brain research 20081215

The antimanic-like effect of tamoxifen: Behavioural comparison with other PKC-inhibiting and antiestrogenic drugs.

Progress in neuro-psychopharmacology & biological psychiatry 20081212

Adenosine A2A and beta-adrenergic calcium transient and contractile responses in rat ventricular myocytes.

American journal of physiology. Heart and circulatory physiology 20081201

Natural feed additive of Macleaya cordata: safety assessment in rats a 90-day feeding experiment.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081201

PKMzeta maintains spatial, instrumental, and classically conditioned long-term memories.

PLoS biology 20081201

Iodine-mediated electrophilic cyclization of 2-alkynyl-1-methylene azide aromatics leading to highly substituted isoquinolines and its application to the synthesis of norchelerythrine.

Journal of the American Chemical Society 20081119

Structure-activity relationship studies of phenanthridine-based Bcl-XL inhibitors.

Journal of medicinal chemistry 20081113

Modulation of Na+-H+ exchange isoforms NHE1 and NHE3 by insulin-like growth factor-1 in isolated bovine articular chondrocytes.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20081101

Impact of protein kinase C activation on epileptiform activity in the hippocampal slice.

Epilepsy research 20081101

Effects of 18-glycyrrhetinic acid on serine 368 phosphorylation of connexin43 in rat neonatal cardiomyocytes.

Cell biology international 20081101

Activation of the RAF/mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase pathway mediates apoptosis induced by chelerythrine in osteosarcoma.

Clinical cancer research : an official journal of the American Association for Cancer Research 20081015

Testosterone and dihydrotestosterone inhibit gallbladder motility through multiple signalling pathways.

Steroids 20081001

Calcium sensitization in human esophageal muscle: role for RhoA kinase in maintenance of lower esophageal sphincter tone.

The Journal of pharmacology and experimental therapeutics 20081001

Vasoactive intestinal peptide increases cystic fibrosis transmembrane conductance regulator levels in the apical membrane of Calu-3 cells through a protein kinase C-dependent mechanism.

The Journal of pharmacology and experimental therapeutics 20081001

Site-specific binding of chelerythrine and sanguinarine to single pyrimidine bulges in hairpin DNA.

Analytical and bioanalytical chemistry 20081001

Production of hydrogen peroxide and redox cycling can explain how sanguinarine and chelerythrine induce rapid apoptosis.

Archives of biochemistry and biophysics 20080901

Comparison of the involvement of protein kinase C in agonist-induced contractions in mouse aorta and corpus cavernosum.

European journal of pharmacology 20080820

N-oleoyldopamine, a novel endogenous capsaicin-like lipid, protects the heart against ischemia-reperfusion injury via activation of TRPV1.

American journal of physiology. Heart and circulatory physiology 20080801

Nitric oxide induces heat shock protein 72 production and delayed protection against myocardial ischemia in rabbits via activating protein kinase C.

Chinese medical journal 20080620

Insulin effects on cardiac Na+/Ca2+ exchanger activity: role of the cytoplasmic regulatory loop.

The Journal of biological chemistry 20080613

Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

Journal of medicinal chemistry 20080612

Chelerythrine and dihydrochelerythrine induce G1 phase arrest and bimodal cell death in human leukemia HL-60 cells.

Toxicology in vitro : an international journal published in association with BIBRA 20080601

Volume-sensitive NADPH oxidase activity and taurine efflux in NIH3T3 mouse fibroblasts.

American journal of physiology. Cell physiology 20080601

Apelin decreases the SR Ca2+ content but enhances the amplitude of [Ca2+]i transient and contractions during twitches in isolated rat cardiac myocytes.

American journal of physiology. Heart and circulatory physiology 20080601

Complex regulation of store-operated Ca2+ entry pathway by PKC-epsilon in vascular SMCs.

American journal of physiology. Cell physiology 20080601

Role of PKCepsilon in PGF2alpha-stimulated MMP-2 secretion from human ciliary muscle cells.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20080601

Macleaya cordata extract and Sangrovit genotoxicity. Assessment in vivo.

Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20080601

Separation of sanguinarine and chelerythrine in Macleaya cordata (Willd) R. Br. based on methyl acrylate-co-divinylbenzene macroporous adsorbents.

Journal of chromatography. A 20080523

Diverse properties of store-operated TRPC channels activated by protein kinase C in vascular myocytes.

The Journal of physiology 20080515

The increase in retinal cells proliferation induced by FGF2 is mediated by tyrosine and PI3 kinases.

Neurochemical research 20080501

Molecular interaction in the mouse PAG between NMDA and opioid receptors in morphine-induced acute thermal nociception.

Journal of neurochemistry 20080401

Epinephrine increases phosphorylation of MAP-2c in rat pheochromocytoma cells (PC12 Cells) via a protein kinase C- and mitogen activated protein kinase-dependent mechanism.

Journal of proteome research 20080401

A decisive role of mitochondria in defining rate and intensity of apoptosis induction by different alkaloids.

Toxicology letters 20080401

Chelerythrine induces apoptosis through a Bax/Bak-independent mitochondrial mechanism.

The Journal of biological chemistry 20080328

Chelerythrine treatment influences the balance of pro- and anti-apoptotic signaling pathways in the remote myocardium after infarction.

Molecular and cellular biochemistry 20080301

Low-dose morphine induces hyperalgesia through activation of G alphas, protein kinase C, and L-type Ca 2+ channels in rats.

Journal of neuroscience research 20080201

Differential effect of sanguinarine, chelerythrine and chelidonine on DNA damage and cell viability in primary mouse spleen cells and mouse leukemic cells.

Cell biology international 20080201

Conventional protein kinase C isoenzymes undergo dephosphorylation in neutrophil-like HL-60 cells treated by chelerythrine or sanguinarine.

Cell biology and toxicology 20080101

Cardioprotection induced by hydrogen sulfide preconditioning involves activation of ERK and PI3K/Akt pathways.

Pflugers Archiv : European journal of physiology 20080101

Identification of a PKCepsilon-dependent regulation of myocardial contraction by epicatechin-3-gallate.

American journal of physiology. Heart and circulatory physiology 20080101

H2S preconditioning-induced PKC activation regulates intracellular calcium handling in rat cardiomyocytes.

American journal of physiology. Cell physiology 20080101

Sevoflurane enhances ethanol-induced cardiac preconditioning through modulation of protein kinase C, mitochondrial KATP channels, and nitric oxide synthase, in guinea pig hearts.

Anesthesia and analgesia 20080101

[Changes in the DNA content in EGF-stimulated ciliate Tetrahymena pyriformis under effect of caffeine, KCl, and inhibitors of PLC and PKC].

Tsitologiia 20080101

[Effect of ionising irradiation on outward potassium current in the aorta smooth muscle cells in rats: the role of protein kinase C].

Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20080101

A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.

Proceedings of the National Academy of Sciences of the United States of America 20071218

Opening the calcium-activated potassium channel participates in the cardioprotective effect of puerarin.

European journal of pharmacology 20071128

Disuse of rat muscle in vivo reduces protein kinase C activity controlling the sarcolemma chloride conductance.

The Journal of physiology 20071101

Oxytocin and vasopressin stimulate anion secretion by human and porcine vas deferens epithelia.

Biology of reproduction 20070901

Oxidative stress and increased eNOS and NADPH oxidase expression in mouse microvessel endothelial cells.

Journal of cellular physiology 20070901

Ischemic preconditioning targets the reperfusion phase.

Basic research in cardiology 20070901

Protein kinase C protects preconditioned rabbit hearts by increasing sensitivity of adenosine A2b-dependent signaling during early reperfusion.

Journal of molecular and cellular cardiology 20070901

Berberine suppresses inflammatory agents-induced interleukin-1beta and tumor necrosis factor-alpha productions via the inhibition of IkappaB degradation in human lung cells.

Pharmacological research 20070901

PKC activation sets an upper limit to the functional plasticity of GABAergic transmission induced by endogenous neurosteroids.

The European journal of neuroscience 20070901

Signal transduction mechanisms of CD137 ligand in human monocytes.

Cellular signalling 20070901

Involvement of the protein kinase Cgamma isoform in development of tolerance to nitrous oxide-induced antinociception in mice.

Neuroscience 20070824

Urocortin prevents mitochondrial permeability transition in response to reperfusion injury indirectly by reducing oxidative stress.

American journal of physiology. Heart and circulatory physiology 20070801

Localization of intracellular compartments that exchange Na,K-ATPase molecules with the plasma membrane in a hormone-dependent manner.

British journal of pharmacology 20070801

A minor role for Ca2+ sensitization in sustained contraction through activation of muscarinic receptor in circular muscle of rat distal colon.

Pflugers Archiv : European journal of physiology 20070701

Landiolol has cardioprotective effects against reperfusion injury in the rat heart via the PKCepsilon signaling pathway.

Free radical research 20070701

Role of L-type calcium channels and PKC in active tone development in rabbit coronary artery.

American journal of physiology. Heart and circulatory physiology 20070601

Protein kinase C regulates vascular myogenic tone through activation of TRPM4.

American journal of physiology. Heart and circulatory physiology 20070601

Verrucotoxin inhibits KATP channels in cardiac myocytes through a muscarinic M3 receptor-PKC pathway.

European journal of pharmacology 20070601

Delayed protection of tetramethylpyrazine on neonatal rat cardiomyocytes subjected to anoxia-reoxygenation injury.

Basic & clinical pharmacology & toxicology 20070601

[Effect of Chelerythrine on glucosyltransferase and water-insoluble glucan of Streptococcus mutans].

Shanghai kou qiang yi xue = Shanghai journal of stomatology 20070601

Effects of PKC on inhibition of delayed rectifier potassium currents by N/OFQ.

Biochemical and biophysical research communications 20070511

PKC blockade differentially affects aversive but not appetitive gustatory memories.

Brain research 20070507

M1 muscarinic receptor modulation of Kir2 channels enhances temporal summation of excitatory synaptic potentials in prefrontal cortex pyramidal neurons.

Journal of neurophysiology 20070501

Taurodeoxycholate modulates apical Cl-/OH- exchange activity in Caco2 cells.

Digestive diseases and sciences 20070501

Endothelin-1 accentuates the proatherosclerotic effects associated with C-reactive protein.

The Journal of thoracic and cardiovascular surgery 20070501

The pH hypothesis of postconditioning: staccato reperfusion reintroduces oxygen and perpetuates myocardial acidosis.

Circulation 20070410

Role of protein kinase C in aldosterone-induced non-genomic inhibition of basolateral potassium channels in human colonic crypts.

The Journal of steroid biochemistry and molecular biology 20070401

Extracellular signal-regulated kinase 1/2-mediated transcriptional regulation of G-protein-coupled receptor kinase 3 expression in neuronal cells.

The Journal of pharmacology and experimental therapeutics 20070401

A61603-induced contractions of the porcine meningeal artery are mediated by alpha1- and alpha2-adrenoceptors.

Basic & clinical pharmacology & toxicology 20070401

Cardioprotective properties of humoral factors released from rat hearts subject to ischemic preconditioning.

Journal of cardiovascular pharmacology 20070401

Receptor regulation of the volume-sensitive efflux of taurine and iodide from human SH-SY5Y neuroblastoma cells: differential requirements for Ca(2+) and protein kinase C.

The Journal of pharmacology and experimental therapeutics 20070301

Variability in the yield of benzophenanthridine alkaloids in wildcrafted vs cultivated bloodroot (Sanguinaria canadensis L.).

Journal of agricultural and food chemistry 20070221

(+/-)3,4-Methylenedioxyamphetamine elicits action potential bursts in a central snail neuron.

Experimental neurology 20070201

Protein kinase C-mediated modulation of glutamate transporter activity in rat retina.

Current eye research 20070201

[Effect of Chelerythrine on cell surface hydrophobicity and adherence of Streptococcus mutans].

Shanghai kou qiang yi xue = Shanghai journal of stomatology 20070201

Activation of kappa-opioid receptor as a method for prevention of ischemic and reperfusion arrhythmias: role of protein kinase C and K(ATP) channels.

Bulletin of experimental biology and medicine 20070201

Synaptic strength at the thalamocortical input to layer IV neonatal barrel cortex is regulated by protein kinase C.

Neuropharmacology 20070101

Two distinct signaling pathways for regulation of spontaneous local Ca2+ release by phospholipase C in airway smooth muscle cells.

Pflugers Archiv : European journal of physiology 20070101

Postjunctional synergism of norepinephrine with ATP and diadenosine tetraphosphate in Guinea pig vas deferens. Role of protein kinase C and Myosin light chain phosphatase.

Pharmacology 20070101

[Effect of adrenocorticotropic hormone on the caspase-3 level and DNA fragmentation in hyperplasia tissue of human adrenals].

Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20070101

Angiotensin II activates two cation conductances with distinct TRPC1 and TRPC6 channel properties in rabbit mesenteric artery myocytes.

The Journal of physiology 20061201

Chelerythrine and sanguinarine dock at distinct sites on BclXL that are not the classic BH3 binding cleft.

Journal of molecular biology 20061201

Positive inotropic effects of carbon monoxide-releasing molecules (CO-RMs) in the isolated perfused rat heart.

British journal of pharmacology 20061201

Nucleotide regulation of the voltage-dependent nonselective cation conductance in murine colonic myocytes.

American journal of physiology. Cell physiology 20061101

Characterization of beta-hexosaminidase secretion in rabbit lacrimal gland.

Experimental eye research 20061101

The effect of chelerythrine on cell growth, apoptosis, and cell cycle in human normal and cancer cells in comparison with sanguinarine.

Cell biology and toxicology 20061101

Bone marrow cells have a potent anti-ischemic effect against myocardial cell death in humans.

The Journal of thoracic and cardiovascular surgery 20061101

Preconditioning by 17beta-estradiol in isolated rat heart depends on PI3-K/PKB pathway, PKC, and ROS.

American journal of physiology. Heart and circulatory physiology 20061001

Signal transduction pathways involved in non-genomic action of estrone on vascular tissue.

Steroids 20061001

FRET analysis reveals a critical conformational change within the Na,K-ATPase alpha1 subunit N-terminus during GPCR-dependent endocytosis.

FEBS letters 20060918

Effects of hyposmotic stress on exocytosis in isolated turbot, Scophthalmus maximus, hepatocytes.

Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20060901

Calcium channel and glutamate receptor activities regulate actin organization in salamander retinal neurons.

The Journal of physiology 20060901

Quaternary benzo[c]phenathridine alkaloids sanguinarine and chelerythrine do not affect transcriptional activity of aryl hydrocarbon receptor: analyses in rat hepatoma cell line H4IIE.luc.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060901

Is protein kinase C (PKC) involved in nociception?

The International journal of neuroscience 20060901

DNA-binding affinities and sequence selectivity of quaternary benzophenanthridine alkaloids sanguinarine, chelerythrine, and nitidine.

Bioorganic & medicinal chemistry 20060815

Phosphorylation at the hydrophobic site of protein kinase C Apl II is increased during intermediate term facilitation.

Neuroscience 20060811

Modulation of cardiac sarcoplasmic reticulum calcium release by aenosine: a protein kinase C- dependent pathway.

Molecular and cellular biochemistry 20060801

Signalling pathways involved in hypertonicity- and acidification-induced activation of Na+/H+ exchange in trout hepatocytes.

The Journal of experimental biology 20060801

[Protective effect of protein kinase C and mitogen-activated protein kinases and its mechanism in liver ischemic preconditioning].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20060801

Elevated endothelin-1 levels impair nitric oxide homeostasis through a PKC-dependent pathway.

Circulation 20060704

Relaxin family peptide receptors RXFP1 and RXFP2 modulate cAMP signaling by distinct mechanisms.

Molecular pharmacology 20060701

Novel alpha1-adrenergic receptor signaling pathways: secreted factors and interactions with the extracellular matrix.

Molecular pharmacology 20060701

Rho-kinase contributes to hypoxia/reoxygenation-induced cerebral endothelial dysfunction.

Journal of cardiovascular pharmacology 20060701

Effects of sanguinarine and chelerythrine on the cell cycle and apoptosis.

Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20060701

Protein kinase C zeta mediates epidermal growth factor-induced growth of head and neck tumor cells by regulating mitogen-activated protein kinase.

Cancer research 20060615

Apoptotic response of uveal melanoma cells upon treatment with chelidonine, sanguinarine and chelerythrine.

Cancer letters 20060608

Recent advances in targeting regulators of apoptosis in cancer cells for therapeutic gain.

Expert opinion on investigational drugs 20060601

[Experimental study of the inhibitory effects of Chelidonium majus L. extractive on Streptococcus mutans in vitro].

Shanghai kou qiang yi xue = Shanghai journal of stomatology 20060601

Activation of protein kinase C enhances 1-methyl-4-phenylpyridinium ion (MPP+)-induced hydroxylradical generation in rat striatum.

Neuroscience letters 20060501

PI3K is required for insulin-stimulated but not EGF-stimulated ERK1/2 activation.

European journal of cell biology 20060501

Infarct-sparing effect of myocardial postconditioning is dependent on protein kinase C signalling.

Cardiovascular research 20060501

Postconditioning protects rabbit hearts through a protein kinase C-adenosine A2b receptor cascade.

Cardiovascular research 20060501

Involvement of protein kinase C in 5-HT-evoked thermal hyperalgesia and spinal fos protein expression in the rat.

Pharmacology, biochemistry, and behavior 20060501

The mitochondrial effects of small organic ligands of BCL-2: sensitization of BCL-2-overexpressing cells to apoptosis by a pyrimidine-2,4,6-trione derivative.

The Journal of biological chemistry 20060414

Geranylgeranylacetone, a noninvasive heat shock protein inducer, induces protein kinase C and leads to neuroprotection against cerebral infarction in rats.

Neuroscience letters 20060403

Role of protein kinase C in the effect of ATP on contractile function of the isolated strip from mouse diaphragm.

Bulletin of experimental biology and medicine 20060401

The beneficial in vitro effects of lovastatin and chelerythrine on relaxatory response to acetylcholine in the perfused mesentric bed isolated from diabetic rats.

European journal of pharmacology 20060327

Protein kinase C inhibitor chelerythrine attenuates the morphine-induced excitatory amino acid release and reduction of the antinociceptive effect of morphine in rats injected intrathecally with pertussis toxin.

Life sciences 20060313

Angiotensin II acutely decreases myocardial stiffness: a novel AT1, PKC and Na+/H+ exchanger-mediated effect.

British journal of pharmacology 20060301

Salviae miltiorrhizae radix increases dopamine release of rat and pheochromocytoma PC12 cells.

Phytotherapy research : PTR 20060301

Effects of intravenous anesthetics on the activity of glutamate transporter EAAT3 expressed in Xenopus oocytes: evidence for protein kinase C involvement.

European journal of pharmacology 20060215

Investigation of sanguinarine and chelerythrine effects on CYP1A1 expression and activity in human hepatoma cells.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060201

Reduction of infarct size with D-myo-inositol trisphosphate: role of PI3-kinase and mitochondrial K(ATP) channels.

American journal of physiology. Heart and circulatory physiology 20060201

Protective effect of chelerythrine on gentamicin-induced nephrotoxicity.

Cell biochemistry and function 20060101

Impact of inhibition of Qo site of mitochondrial complex III with myxothiazol on persistent sodium currents via superoxide and protein kinase C in rat hippocampal CA1 cells.

Neurobiology of disease 20060101

Palmitate induces tumor necrosis factor-alpha expression in C2C12 skeletal muscle cells by a mechanism involving protein kinase C and nuclear factor-kappaB activation.

Endocrinology 20060101

Regulation of cardiac inwardly rectifying potassium current IK1 and Kir2.x channels by endothelin-1.

Journal of molecular medicine (Berlin, Germany) 20060101

Inhibition of experimental proliferative vitreoretinopathy with protein kinase C inhibitor (chelerythrine chloride) and melatonin.

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20060101

Human metallothionein gene expression is upregulated by beta-thujaplicin: possible involvement of protein kinase C and reactive oxygen species.

Biological & pharmaceutical bulletin 20060101

Lysophosphatidylcholine augments Ca(v)3.2 but not Ca(v)3.1 T-type Ca(2+) channel current expressed in HEK-293 cells.

Pharmacology 20060101

Analysis of secondary metabolites from eschscholtzia californica by high-performance liquid chromatography.

Phytochemical analysis : PCA 20060101

Role of oxidative/nitrosative stress in the tolerance to ischemia/reperfusion injury in cardiomyopathic hamster heart.

Antioxidants & redox signaling 20060101

Rapid determination of protopine, allocryptopine, sanguinarine and chelerythrine in fruits of Macleaya cordata by microwave-assisted solvent extraction and HPLC-ESI/MS.

Phytochemical analysis : PCA 20060101

Site-specific binding of chelerythrine to single cytosine and thymine bulges in DNA hairpins.

Nucleic acids symposium series (2004) 20060101

Gender differences in cardioprotection against ischemia/reperfusion injury in adult rat hearts: focus on Akt and protein kinase C signaling.

The Journal of pharmacology and experimental therapeutics 20051201

Aldosterone and tight junctions: modulation of claudin-4 phosphorylation in renal collecting duct cells.

American journal of physiology. Cell physiology 20051201

Pivotal role of NOX-2-containing NADPH oxidase in early ischemic preconditioning.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051201

Relative contribution of Rho kinase and protein kinase C to myogenic tone in rat cerebral arteries in hypertension.

American journal of physiology. Heart and circulatory physiology 20051101

Activation of PKC modulates blood-brain barrier endothelial cell permeability changes induced by hypoxia and posthypoxic reoxygenation.

American journal of physiology. Heart and circulatory physiology 20051101

Hepatic injury in rats with obstructive jaundice: roles of the protein kinase C signal pathway and cytoprotection of fructose.

Hepatobiliary & pancreatic diseases international : HBPD INT 20051101

Effects of chronic exposure to ethanol on glutamate transporter EAAT3 expressed in Xenopus oocytes: evidence for protein kinase C involvement.

Alcoholism, clinical and experimental research 20051101

Subcellular localization of iron regulatory proteins to Golgi and ER membranes.

Journal of cell science 20051001

Divergent regulation of Pyk2/CAKbeta phosphorylation by Ca2+ and cAMP in the hippocampus.

Biochimica et biophysica acta 20050930

Role of the protein kinase C-epsilon-Raf-1-MEK-1/2-p44/42 MAPK signaling cascade in the activation of signal transducers and activators of transcription 1 and 3 and induction of cyclooxygenase-2 after ischemic preconditioning.

Circulation 20050927

Effects of the limited analyte solubility on its mobility and zone shape: electrophoretic behavior of sanguinarine and chelerythrine around pH 7.

Electrophoresis 20050901

Pharmacological preconditioning with bradykinin affords myocardial protection through NO-dependent mechanisms.

International heart journal 20050901

Mechanisms of erythropoietin-mediated cardioprotection during ischemia-reperfusion injury: role of protein kinase C and phosphatidylinositol 3-kinase signaling.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050801

Modulation of tumor necrosis factor-alpha and oxidative stress through protein kinase C and P42/44 mitogen-activated protein kinase in lead increases lipopolysaccharide-induced liver damage in rats.

Shock (Augusta, Ga.) 20050801

Highly stable phenanthridinium frameworks as a new class of tunable DNA binding agents with cytotoxic properties.

Journal of medicinal chemistry 20050714

NAD(P)H-dependent superoxide production in platelets: the role of angiotensin II and protein kinase C.

Clinical biochemistry 20050701

AMPA receptor stimulation increases alpha5beta1 integrin surface expression, adhesive function and signaling.

Journal of neurochemistry 20050701

Mechanisms of the protective effects of urocortin on coronary endothelial function during ischemia-reperfusion in rat isolated hearts.

British journal of pharmacology 20050601

Annexin-1 peptide Anx-1(2-26) protects adult rat cardiac myocytes from cellular injury induced by simulated ischaemia.

British journal of pharmacology 20050601

Cardioprotective effects of Ilex paraguariensis extract: evidence for a nitric oxide-dependent mechanism.

Clinical nutrition (Edinburgh, Scotland) 20050601

The interaction of isoflurane and protein kinase C-activators on sarcolemmal KATP channels.

Anesthesia and analgesia 20050601

Study of the inhibition of alpha-amylase by the benzo[c]phenanthridine alkaloids sanguinarine and chelerythrine.

Journal of enzyme inhibition and medicinal chemistry 20050601

Protein kinase C is selectively involved in the mechanisms of long-term synaptic plasticity.

Bulletin of experimental biology and medicine 20050601

Platelet-activating factor induces cardioprotection in isolated rat heart akin to ischemic preconditioning: role of phosphoinositide 3-kinase and protein kinase C activation.

American journal of physiology. Heart and circulatory physiology 20050501

Remifentanil mimics cardioprotective effect of ischemic preconditioning via protein kinase C activation in open chest of rats.

Acta pharmacologica Sinica 20050501

In vitro assessment of cytotoxic agent combinations for hormone-refractory prostate cancer treatment.

Anti-cancer drugs 20050401

Antecedent ethanol ingestion prevents postischemic leukocyte adhesion and P-selectin expression by a protein kinase C-dependent mechanism.

Digestive diseases and sciences 20050401

Induction of human leukemia HL-60 cell differentiation via a PKC/ERK pathway by helenalin, a pseudoguainolide sesquiterpene lactone.

European journal of pharmacology 20050328

Staurosporine inhibits voltage-dependent K+ current through a PKC-independent mechanism in isolated coronary arterial smooth muscle cells.

Journal of cardiovascular pharmacology 20050301

Global kinase screening. Applications of frontal affinity chromatography coupled to mass spectrometry in drug discovery.

Analytical chemistry 20050301

Hypotonic shock mediation by p38 MAPK, JNK, PKC, FAK, OSR1 and SPAK in osmosensing chloride secreting cells of killifish opercular epithelium.

The Journal of experimental biology 20050301

Protein kinase C zeta is required for epidermal growth factor-induced chemotaxis of human breast cancer cells.

Cancer research 20050215

Signal transduction of the prophenoloxidase activating system of prawn haemocytes triggered by CpG oligodeoxynucleotides.

Fish & shellfish immunology 20050201

Protein kinase C delta is not activated by caspase-3 and its inhibition is sufficient to induce apoptosis in the colon cancer line, COLO 205.

Cellular signalling 20050201

alpha1A- but not alpha1B-adrenergic receptors precondition the ischemic heart by a staurosporine-sensitive, chelerythrine-insensitive mechanism.

Cardiovascular research 20050201

Synergistic stimulatory effect of 12-O-tetradecanoylphorbol-13-acetate and capsaicin on macrophage differentiation in HL-60 and HL-525 human myeloid leukemia cells.

International journal of oncology 20050201

Insulin-induced phosphorylation of ENaC correlates with increased sodium channel function in A6 cells.

American journal of physiology. Cell physiology 20050101

An oxidative stress mechanism mediates chelerythrine-induced heparin-binding EGF-like growth factor ectodomain shedding.

Journal of cellular biochemistry 20050101

Deferoxamine induces prolonged cardiac preconditioning via accumulation of oxygen radicals.

Free radical biology & medicine 20050101

Synthesis of oxychelerythrine using lithiated toluamide-benzonitrile cycloaddition.

Chemical & pharmaceutical bulletin 20050101

Protective effects of insulin during ischemia-reperfusion injury in hamster cheek pouch microcirculation.

Journal of vascular research 20050101

Secretion of ATP from Schwann cells in response to uridine triphosphate.

The European journal of neuroscience 20050101

Effect of pravastatin on impaired endothelium-dependent relaxation induced by lysophosphatidylcholine in rat aorta.

Acta pharmacologica Sinica 20050101

Diazoxide ameliorates microcirculatory disturbances through PKC-dependent pathway in I/R-injured rat cremaster muscles.

Journal of biomedical science 20050101

Roles of protein kinase C and fructose in hepatic injury caused by obstructive jaundice.

Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20050101

Metabolic arrest and its regulation in anoxic eel hepatocytes.

Physiological and biochemical zoology : PBZ 20050101

Effects of angiotensin II on the pericyte-containing microvasculature of the rat retina.

The Journal of physiology 20041215

Hypoxic pulmonary vasoconstriction and pulmonary artery tissue cytokine expression are mediated by protein kinase C.

American journal of physiology. Lung cellular and molecular physiology 20041201

Dual concentration-dependent effects of phorbol 12, 13-dibutyrate on spontaneous and acetylcholine-induced electrical responses recorded from isolated circular smooth muscle of the guinea-pig stomach antrum.

Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20041201

Silent information regulator 2alpha, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes.

Circulation research 20041112

Bmx, a member of the Tec family of nonreceptor tyrosine kinases, is a novel participant in pharmacological cardioprotection.

American journal of physiology. Heart and circulatory physiology 20041101

Spontaneous activity and its cholinergic modulation in circular smooth muscle isolated from guinea-pig stomach antrum.

Pflugers Archiv : European journal of physiology 20041101

Extracellular signal-regulated kinase (ERK) in glucose-induced and endothelin-mediated fibronectin synthesis.

Laboratory investigation; a journal of technical methods and pathology 20041101

Protein kinase C inhibitors produce mitochondrial flavoprotein oxidation in cardiac myocytes.

Anesthesia and analgesia 20041101

17beta-estradiol reduces the effect of metabolic inhibition on gap junction intercellular communication in rat cardiomyocytes via the estrogen receptor.

Journal of molecular and cellular cardiology 20041101

Chronic exercise improves myocardial inotropic reserve capacity through alpha1-adrenergic and protein kinase C-dependent effects in Senescent rats.

The journals of gerontology. Series A, Biological sciences and medical sciences 20041101

Down-regulation of connexin43 in early myocardial ischemia and protective effect by ischemic preconditioning in rat hearts in vivo.

Japanese heart journal 20041101

Endothelin-1 enhances the activity of Na+/Ca2+ exchanger type 1 in renal epithelial cells.

Journal of cardiovascular pharmacology 20041101

Differential interplay between protein kinase C and Rho-kinase in the endothelin-1-induced and pressure-induced contractions of rat posterior cerebral artery.

Journal of cardiovascular pharmacology 20041101

Protein kinase C overactivity impairs prefrontal cortical regulation of working memory.

Science (New York, N.Y.) 20041029

Gene therapy of endothelial nitric oxide synthase and manganese superoxide dismutase restores delayed wound healing in type 1 diabetic mice.

Circulation 20041019

Intermittent hypoxia protects the rat heart against ischemia/reperfusion injury by activating protein kinase C.

Life sciences 20041008

Aggregation and other intermolecular interactions of biological buffers observed by capillary electrophoresis and UV photometry.

Journal of chromatography. A 20041008

Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels.

Circulation research 20041001

Activation of protein kinase C contributes to the isoflurane-induced improvement of functional and metabolic recovery in isolated ischemic rat hearts.

Anesthesia and analgesia 20041001

Arg-vasopressin increases proliferation of human osteoblast-like cells and decreases production of interleukin-6 and macrophage colony-stimulating factor.

Regulatory peptides 20040915

Regulation of tumor necrosis factor-alpha in glioma cells by lead and lipopolysaccharide: involvement of common signaling pathway.

Toxicology letters 20040910

Effect of protein kinase C blockade on phosphorylation of NR1 in dorsal horn and spinothalamic tract cells caused by intradermal capsaicin injection in rats.

Brain research 20040910

Systemic regulation of vascular NAD(P)H oxidase activity and nox isoform expression in human arteries and veins.

Arteriosclerosis, thrombosis, and vascular biology 20040901

Investigation of signaling pathways that mediate the inotropic effect of urotensin-II in human heart.

Cardiovascular research 20040901

Role of protein kinase C in the excitatory action of cholinergic nerve stimulation on spontaneous activity of circular smooth muscle isolated from the guinea-pig stomach antrum.

Pflugers Archiv : European journal of physiology 20040901

Effects of alpha1-adrenergic stimulation on normal and hypertrophied mouse hearts. Relation to caveolin-3 expression.

Cardiovascular research 20040815

Role of PKCalpha and PKCiota in phenylephrine-induced contraction of rat corpora cavernosa.

International journal of impotence research 20040801

Substance P induces inward current and regulates pacemaker currents through tachykinin NK1 receptor in cultured interstitial cells of Cajal of murine small intestine.

European journal of pharmacology 20040708

Chelerythrine and other benzophenanthridine alkaloids block the human P2X7 receptor.

British journal of pharmacology 20040701

Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system.

The American journal of pathology 20040701

IgA immune complex blunts the contraction of cultured mesangial cells through the inhibition of protein kinase C and intracellular calcium.

The Chinese journal of physiology 20040630

Endothelial dysfunction in aortic rings and mesenteric beds isolated from deoxycorticosterone acetate hypertensive rats: possible involvement of protein kinase C.

European journal of pharmacology 20040628

Capillary electrophoretic studies of acid-base properties of sanguinarine and chelerythrine alkaloids.

Journal of chromatography. A 20040618

Experimental evidence for the limiting role of enzymatic reactions in chemoattractant-induced pseudopod extension in human neutrophils.

The Journal of biological chemistry 20040604

Transient glucose deprivation causes upregulation of heme oxygenase-1 and cyclooxygenase-2 expression in cardiac fibroblasts.

Journal of molecular and cellular cardiology 20040601

Mechanisms involved in carbachol-induced Ca(2+) sensitization of contractile elements in rat proximal and distal colon.

British journal of pharmacology 20040601

Cytoskeletal restraints regulate homotypic ALCAM-mediated adhesion through PKCalpha independently of Rho-like GTPases.

Journal of cell science 20040601

Regulation of proangiogenic factor CCN1 in cardiac muscle: impact of ischemia, pressure overload, and neurohumoral activation.

Circulation 20040511

Involvement of protein kinase C-related anti-apoptosis signaling in radiation-induced apoptosis in murine thymic lymphoma(3SBH5) cells.

Radiation research 20040501

Rapid change of glucose concentration promotes mesangial cell proliferation via VEGF: inhibitory effects of thiazolidinedione.

Biochemical and biophysical research communications 20040423

Epidermal growth factor induces fibroblast contractility and motility via a protein kinase C delta-dependent pathway.

The Journal of biological chemistry 20040409

Protein kinase C plays an essential role in sildenafil-induced cardioprotection in rabbits.

American journal of physiology. Heart and circulatory physiology 20040401

Hypoxia selection of death-resistant cells. A role for Bcl-X(L).

The Journal of biological chemistry 20040305

Exocytosis of a complement component C3-like protein by tunicate hemocytes.

Developmental and comparative immunology 20040301

Opioid-mediated modulation of calcium currents in striatal and pallidal neurons following reserpine treatment: focus on kappa response.

Synapse (New York, N.Y.) 20040301

Delayed preconditioning of the human myocardium: signal transduction and clinical implications.

Cardiovascular research 20040215

Hypoxia increases calcium flux through cortical neuron glutamate receptors via protein kinase C.

Journal of neurochemistry 20040201

Troglitazone acts by PPARgamma and PPARgamma-independent pathways on LLC-PK1-F+ acid-base metabolism.

American journal of physiology. Renal physiology 20040101

Sanguinarine and chelerythrine: assessment of safety on pigs in ninety days feeding experiment.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040101

CD3 receptor modulation in Jurkat leukemic cell line.

Folia histochemica et cytobiologica 20040101

Chelerythrine stimulates GSH transport by rat Mrp2 (Abcc2) expressed in canine kidney cells.

American journal of physiology. Gastrointestinal and liver physiology 20031201

Mechanisms of myocardial ischemic preconditioning are age related: PKC-epsilon does not play a requisite role in old rabbits.

Journal of applied physiology (Bethesda, Md. : 1985) 20031201

Nicotinic receptor-mediated regulation of the dopamine transporter in rat prefrontocortical slices following chronic in vivo administration of nicotine.

Schizophrenia research 20031201

Influence of alpha2-autoreceptor stimulation on the facilitation by angiotensin II and bradykinin of noradrenaline release.

Naunyn-Schmiedeberg's archives of pharmacology 20031201

Insulin-induced improvement of postischemic recovery is abolished by inhibition of protein kinase C in rat heart.

The Journal of thoracic and cardiovascular surgery 20031201

Converting enzyme inhibitor temocaprilat prevents high glucose-mediated suppression of human aortic endothelial cell proliferation.

Journal of cardiovascular pharmacology 20031201

Isoform-selectivity of PKC inhibitors acting at the regulatory and catalytic domain of mammalian PKC-alpha, -betaI, -delta, -eta and -zeta.

Journal of enzyme inhibition and medicinal chemistry 20031201

Electrophoretic investigation of interactions of sanguinarine and chelerythrine with molecules containing mercapto group.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031125

The effects of protein kinase C activity on synaptic transmission in two areas of rat hippocampus.

Brain research 20031114

Constitutive cytoplasmic localization of p21(Waf1/Cip1) affects the apoptotic process in monocytic leukaemia.

Leukemia 20031101

Immunocytochemical detection of GLUT2 at the rat intestinal brush-border membrane.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20031101

Cellular redistribution of inducible Hsp70 protein in the human and rabbit heart in response to the stress of chronic hypoxia: role of protein kinases,

The Journal of biological chemistry 20031031

Signaling via histamine receptors in cat duodenal smooth muscle cells.

Molecules and cells 20031031

Involvement of protein kinase C in the adaptive changes of cholinergic neurons to sympathetic denervation in the guinea pig myenteric plexus.

Life sciences 20031003

Endothelin-1 limits vascular smooth muscle beta-adrenergic receptor sensitivity by a PKC-dependent pathway.

Journal of cardiovascular pharmacology 20031001

HL-1 myocytes exhibit PKC and K(ATP) channel-dependent delta opioid preconditioning.

The Journal of surgical research 20031001

Protein kinase C inhibition induces DNA fragmentation in COLO 205 cells which is blocked by cysteine protease inhibition but not mediated through caspase-3.

Experimental cell research 20030910

Kinase-dependent loss of Na+ channel slow-inactivation in rat CA1 hippocampal pyramidal cell dendrites after brief exposure to convulsants.

The European journal of neuroscience 20030901

Signaling pathway for aloe-emodin-induced apoptosis in human H460 lung nonsmall carcinoma cell.

International journal of cancer 20030810

Protein kinase C modifications of VE-cadherin, p120, and beta-catenin contribute to endothelial barrier dysregulation induced by thrombin.

American journal of physiology. Lung cellular and molecular physiology 20030801

Chelerythrin activates caspase-8, downregulates FLIP long and short, and overcomes resistance to tumour necrosis factor-related apoptosis-inducing ligand in KG1a cells.

British journal of haematology 20030801

Human beta(3)-adrenoreceptors couple to KvLQT1/MinK potassium channels in Xenopus oocytes via protein kinase C phosphorylation of the KvLQT1 protein.

Naunyn-Schmiedeberg's archives of pharmacology 20030801

Diverse regulation of atrial natriuretic peptide secretion by serotonin receptor subtypes.

Cardiovascular research 20030801

Inhibition of alpha, betaI, delta, eta, and zeta protein kinase C isoforms by xanthonolignoids.

Journal of enzyme inhibition and medicinal chemistry 20030801

Co-stimulation of mGluR5 and N-methyl-D-aspartate receptors is required for potentiation of excitatory synaptic transmission in hippocampal neurons.

The Journal of biological chemistry 20030725

Alpha-2 adrenoceptor mediating the facilitatory effect of norepinephrine on the glycine response in the spinal dorsal horn neuron of the rat.

Life sciences 20030704

Protein kinase C-delta mediates adenosine A3 receptor-induced delayed cardioprotection in mouse.

American journal of physiology. Heart and circulatory physiology 20030701

Role of protein kinase C in geranylgeranylacetone-induced expression of heat-shock protein 72 and cardioprotection in the rat heart.

Journal of molecular and cellular cardiology 20030701

Various inotropic effects of angiotensin II in post-ischaemic rat hearts depending on ischaemic time with possible involvement of protein kinase C.

Acta physiologica Scandinavica 20030701

Inhibition of taurine transport by high concentration of glucose in cultured rat cardiomyocytes.

Metabolism: clinical and experimental 20030701

A double-lumen intrathecal catheter for studies of modulation of spinal opiate tolerance.

Journal of neuroscience methods 20030630

Ischaemic tolerance in aged mouse myocardium: the role of adenosine and effects of A1 adenosine receptor overexpression.

The Journal of physiology 20030615

Identification of chelerythrine as an inhibitor of BclXL function.

The Journal of biological chemistry 20030606

Differential regulation of early growth response gene-1 expression by insulin and glucose in vascular endothelial cells.

Arteriosclerosis, thrombosis, and vascular biology 20030601

Adenosine-mediated early preconditioning in mouse: protective signaling and concentration dependent effects.

Cardiovascular research 20030601

Preischemic infusion of alpha-human atrial natriuretic peptide elicits myoprotective effects against ischemia reperfusion in isolated rat hearts.

Molecular and cellular biochemistry 20030601

Differential activation of protein kinase C between ischemic and pharmacological preconditioning in the rabbit heart.

The Japanese journal of physiology 20030601

PKC is required for activation of ROCK by RhoA in human endothelial cells.

Biochemical and biophysical research communications 20030516

Properties of a constitutively active Ca2+-permeable non-selective cation channel in rabbit ear artery myocytes.

The Journal of physiology 20030515

Activation of Mst1 causes dilated cardiomyopathy by stimulating apoptosis without compensatory ventricular myocyte hypertrophy.

The Journal of clinical investigation 20030515

Reactive oxygen species are involved in smoking-induced dysfunction of nitric oxide biosynthesis and upregulation of endothelial nitric oxide synthase: an in vitro demonstration in human coronary artery endothelial cells.

Circulation 20030513

Protein kinase C activation generates superoxide and contributes to impairment of cerebrovasodilation induced by G protein activation after brain injury.

Brain research 20030509

Norepinephrine evoked by potassium depolarization increases interstitial adenosine concentration via activation of ecto-5'-nucleotidase in rat hearts.

The Journal of pharmacology and experimental therapeutics 20030501

Modulation of protein kinase C (PKC)-mediated contraction and the possible role of PKC epsilon in rat mesenteric arteries.

Frontiers in bioscience : a journal and virtual library 20030501

Tyrosine kinase is involved in hemin-induced pyresis.

Archives of pharmacal research 20030501

Chelerythrine and bisindolylmaleimide I prolong cardiac action potentials by protein kinase C-independent mechanism.

European journal of pharmacology 20030411

Inhibition of protein kinase C by synthetic xanthone derivatives.

Bioorganic & medicinal chemistry 20030403

Dopaminergic inhibition of secretin-stimulated choleresis by increased PKC-gamma expression and decrease of PKA activity.

American journal of physiology. Gastrointestinal and liver physiology 20030401

Phosphorylation of protein kinase C sites in NBD1 and the R domain control CFTR channel activation by PKA.

The Journal of physiology 20030401

Control of head morphogenesis in an invertebrate asexually produced larva-like bud ( Cassiopea andromeda; Cnidaria: Scyphozoa).

Development genes and evolution 20030401

The induction of heat shock protein-72 attenuates cisplatin-induced acute renal failure in rats.

Pflugers Archiv : European journal of physiology 20030401

Vasospasm following subarachnoid hemorrhage: evidence against functional upregulation of protein kinase C constrictor pathway.

Neurological research 20030401

Effect of protein kinase C activation and inhibition on rat hepatic stellate cell activation.

Digestive diseases and sciences 20030401

Lipoxin A4 stimulates a cytosolic Ca2+ increase in human bronchial epithelium.

The Journal of biological chemistry 20030328

Vitamin E deficiency reduces surfactant lipid biosynthesis in alveolar type II cells.

Free radical biology & medicine 20030315

Effects of a phorbol ester and cyclosporin A on hippocampal synaptic plasticity in streptozotocin-induced-diabetic rats: reduced sensitivity to phorbol esters.

Neuroscience letters 20030313

[Effects of chelerythrine on cell proliferation and p27 expression of cardiac fibroblasts modulated by arginine vasopressin].

Zhonghua yi xue za zhi 20030310

D-2-amino-5-phosphonopentanoic acid inhibits intrathecal pertussis toxin-induced thermal hyperalgesia and protein kinase Cgamma up-regulation.

Brain research 20030214

The effect of chelerythrine on depolarization-induced force responses in skinned fast skeletal muscle fibres of the rat.

British journal of pharmacology 20030201

Potentiation of glycine responses by dideoxyforskolin and tamoxifen in rat spinal neurons.

The European journal of neuroscience 20030201

PMA decreases the proliferation of retinal cells in vitro: the involvement of acetylcholine and BDNF.

Neurochemistry international 20030101

Natriuretic peptides suppress protein kinase C activity to reduce evoked dopamine efflux from pheochromocytoma (PC12) cells.

Endocrinology 20030101

Role of protein kinase C in central muscarinic inhibitory mechanisms regulating voiding in rats.

Neuroscience 20030101

A calcium/calmodulin kinase pathway connects brain-derived neurotrophic factor to the cyclic AMP-responsive transcription factor in the rat hippocampus.

Neuroscience 20030101

Protein kinase C is involved in clozapine's facilitation of N-methyl-D-aspartate- and electrically evoked responses in pyramidal cells of the medial prefrontal cortex.

Neuroscience 20030101

Adenosine suppresses the response of neurons to gaba in the superficial laminae of the rat spinal dorsal horn.

Neuroscience 20030101

Quaternary benzo[c]phenanthridine alkaloids as inhibitors of dipeptidyl peptidase IV-like activity baring enzymes in human blood plasma and glioma cell lines.

Physiological research 20030101

Attenuation of canine cerebral vasospasm after subarachnoid hemorrhage by protein kinase C inhibitors despite augmented phosphorylation of myosin light chain.

Journal of vascular research 20030101

Pituitary adenylate cyclase-activating polypeptide (PACAP)-evoked increase in cyclic AMP production in chick cerebral cortex: lack of a role of the protein kinase C pathway.

Polish journal of pharmacology 20030101

Modulation of CD40L antigen expression in Jurkat cells: involvement of protein kinase C activity.

Folia histochemica et cytobiologica 20030101

[Effect of inhibiting protein kinase C on calcium sensitivity of contractile apparatus of vascular smooth muscle during vasospasms of different origins].

Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20030101

Differential regulation by Ca(2+) of calmodulin- and PKC-dependent contractile pathways in cat lower oesophageal sphincter.

Autonomic & autacoid pharmacology 20030101

The intracellular pathway of the acetylcholine-induced contraction in cat detrusor muscle cells.

British journal of pharmacology 20021201

Differential mechanisms of morphine antinociceptive tolerance revealed in (beta)arrestin-2 knock-out mice.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20021201

Involvement of 5-HT7 receptors in serotonergic effects on spike afterpotentials in presumed jaw-closing motoneurons of rats.

Brain research 20021108

Phorbol ester stimulates a protein kinase C-mediated agatoxin-TK-sensitive calcium permeability pathway in human red blood cells.

Blood 20021101

Upregulation of myocardial Na+/H+ exchanger induced by chronic treatment with a selective inhibitor.

Journal of molecular and cellular cardiology 20021101

Neurotensin modulates the amplitude and frequency of voltage-activated Ca2+ currents in frog pituitary melanotrophs: implication of the inositol triphosphate/protein kinase C pathway.

The European journal of neuroscience 20021101

Modulation of steroid hydroxylase activity in stably transfected V79MZh11B1 and V79MZh11B2 cells by PKC and PKD inhibitors.

Endocrine research 20021101

Factors contributing to neurotrophin-independent survival of adult sensory neurons.

Brain research 20021025

Interaction between alpha2-autoreceptors and receptors mediating the effects of angiotensin II and bradykinin in the heart of newborn rats.

European journal of pharmacology 20021025

Protein kinase C activation induces phosphatidylserine exposure on red blood cells.

Biochemistry 20021015

Regulation of mdm2 mRNA expression in human breast tumor-derived GI-101A cells.

Life sciences 20021004

The role of serotonin in ischemic cellular damage and the infarct size-reducing effect of sarpogrelate, a 5-hydroxytryptamine-2 receptor blocker, in rabbit hearts.

Journal of the American College of Cardiology 20021002

Different signal transduction pathways are involved during human sperm capacitation induced by biological and pharmacological agents.

Molecular human reproduction 20020901

Regulation of NFkappaB in hepatic ischemic preconditioning.

Journal of the American College of Surgeons 20020901

Inhibitory activity on binding of specific ligands to the human angiotensin II AT(1) and endothelin 1 ET(A) receptors: bioactive benzo[c]phenanthridine alkaloids from the root of Bocconia frutescens.

Planta medica 20020901

Activation of glutamate receptors inhibits Na/K-ATPase of cerebellum granule cells.

Biochemistry. Biokhimiia 20020901

Intestinal ischemia preconditions myocardium: role of protein kinase C and mitochondrial K(ATP) channel.

Cardiovascular research 20020815

Remote preconditioning protects the heart by activating myocardial PKCepsilon-isoform.

Cardiovascular research 20020815

Excitation of smooth muscles isolated from the guinea-pig gastric antrum in response to depolarization.

The Journal of physiology 20020815

DNA adduct formation from quaternary benzo[c]phenanthridine alkaloids sanguinarine and chelerythrine as revealed by the 32P-postlabeling technique.

Chemico-biological interactions 20020815

Two kinase activities are sufficient for sea urchin sperm chromatin decondensation in vitro.

Molecular reproduction and development 20020801

Orphanin FQ/nociceptin-mediated desensitization of opioid receptor-like 1 receptor and mu opioid receptors involves protein kinase C: a molecular mechanism for heterologous cross-talk.

The Journal of pharmacology and experimental therapeutics 20020801

Modulation of volume-sensitive chloride current by noradrenaline in rabbit portal vein myocytes.

The Journal of physiology 20020715

Moderate alcohol consumption induces sustained cardiac protection by activating PKC-epsilon and Akt.

American journal of physiology. Heart and circulatory physiology 20020701

ATP-inhibition of M current in frog sympathetic neurons involves phospholipase C but not Ins P(3), Ca(2+), PKC, or Ras.

Journal of neurophysiology 20020701

Cardioprotection mediated by sphingosine-1-phosphate and ganglioside GM-1 in wild-type and PKC epsilon knockout mouse hearts.

American journal of physiology. Heart and circulatory physiology 20020601

alpha-Adrenergic response and myofilament activity in mouse hearts lacking PKC phosphorylation sites on cardiac TnI.

American journal of physiology. Heart and circulatory physiology 20020601

Dopamine-induced inhibition of Na+-K+-ATPase activity requires integrity of actin cytoskeleton in opossum kidney cells.

Acta physiologica Scandinavica 20020601

Protein kinase C modulators enhance angiotensin II desensitization of guinea pig ileum via maxi-K+ channels.

European journal of pharmacology 20020503

Inhibition of cAMP accumulation by kappa-receptor activation in isolated iris-ciliary bodies: role of phosphodiesterase and protein kinase C.

The Journal of pharmacology and experimental therapeutics 20020501

Angiotensin II increases L-type Ca2+ current in gramicidin D-perforated adult rabbit ventricular myocytes: comparison with conventional patch-clamp method.

Pflugers Archiv : European journal of physiology 20020501

Dual regulation of cardiac Na+-K+ pumps and CFTR Cl- channels by protein kinases A and C.

Pflugers Archiv : European journal of physiology 20020501

Antagonists of protein kinase C inhibit rat retinal glutamate transport activity in situ.

Journal of neurochemistry 20020501

Uptake of (3)H-1-methyl-4-phenylpyridinium ((3)H-MPP(+)) by human intestinal Caco-2 cells is regulated by phosphorylation/dephosphorylation mechanisms.

Biochemical pharmacology 20020415

Preconditioning blocks cardiocyte apoptosis: role of K(ATP) channels and PKC-epsilon.

American journal of physiology. Heart and circulatory physiology 20020401

Role of protein kinase C in control of ethanol-modulated beta-endorphin release from hypothalamic neurons in primary cultures.

The Journal of pharmacology and experimental therapeutics 20020401

Protein kinase Mzeta is necessary and sufficient for LTP maintenance.

Nature neuroscience 20020401

Memory enhancement and formation by atypical PKM activity in Drosophila melanogaster.

Nature neuroscience 20020401

Voltage independence of vasomotion in isolated irideal arterioles of the rat.

The Journal of physiology 20020401

Role of protein kinase C-epsilon in the development of kappa-opioid receptor tolerance to U50,488H in rat ventricular myocytes.

British journal of pharmacology 20020401

Ethanol alters glutamate but not adenosine uptake in rat astrocytes: evidence for protein kinase C involvement.

Neurochemical research 20020401

Effect of modulators of protein kinase C activity on Ca2+ transport in retinal rod microsomes.

Biochemistry. Biokhimiia 20020401

Protective effects of protein kinase C during myocardial ischemia require activation of phosphatidyl-inositol specific phospholipase C.

The Annals of thoracic surgery 20020401

Human urotensin II-induced aorta ring contractions are mediated by protein kinase C, tyrosine kinases and Rho-kinase: inhibition by somatostatin receptor antagonists.

European journal of pharmacology 20020308

Endothelin-induced changes in the physiology of retinal pericytes.

Investigative ophthalmology & visual science 20020301

Effects of fasting on corticosterone production by zona fasciculata-reticularis cells in ovariectomized rats.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20020301

Roles of protein kinase C and alpha-tocopherol in regulation of signal transduction for GATA-4 phosphorylation in HL-1 cardiac muscle cells.

Free radical biology & medicine 20020215

Diverse inhibitors of intracellular signalling act as adenosine receptor antagonists.

Cellular signalling 20020201

Altered PYK2 phosphorylation by ANG II in hypertensive vascular smooth muscle.

American journal of physiology. Heart and circulatory physiology 20020201

myo-Inositol 1,4,5-trisphosphate and Ca(2+)/calmodulin-dependent factors mediate transduction of compression-induced signals in bovine articular chondrocytes.

The Biochemical journal 20020201

Quaternary benzo[c]phenanthridine alkaloids as inhibitors of aminopeptidase N and dipeptidyl peptidase IV.

Phytotherapy research : PTR 20020201

Antisense RNA-mediated suppression of benzophenanthridine alkaloid biosynthesis in transgenic cell cultures of California poppy.

Plant physiology 20020201

Modulation of apoptosis by mitochondrial uncouplers: apoptosis-delaying features despite intrinsic cytotoxicity.

Biochemical pharmacology 20020201

Interaction of chelerythrine with inositol phosphate metabolism.

Fundamental & clinical pharmacology 20020201

Negative inotropic effects of angiotensin II, endothelin-1 and phenylephrine in indo-1 loaded adult mouse ventricular myocytes.

Life sciences 20020125

In vivo evidence for a role of protein kinase C in peripheral nociceptive processing.

British journal of pharmacology 20020101

Signalling pathways involved in the direct effects of IGFBP-5 on breast epithelial cell attachment and survival.

Journal of cellular biochemistry 20020101

Antitumor activity of protein kinase C inhibitors and cisplatin in human head and neck squamous cell carcinoma lines.

Anti-cancer drugs 20020101

PKC-delta inhibition does not block preconditioning-induced preservation in mitochondrial ATP synthesis and infarct size reduction in rats.

Basic research in cardiology 20020101

Roles of the cytoskeleton and of protein phosphorylation events in the osmotic stress response in eel intestinal epithelium.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20020101

[A role of protein kinase C in signal reactions in outer segments of the bovine retinal rods].

Biofizika 20020101

A new phenylpropanoid ester from the bark of Zanthoxylum scandens (Rutaceae).

Zeitschrift fur Naturforschung. C, Journal of biosciences 20020101

Cytotoxicity of natural compounds in hepatocyte cell culture models. The case of quaternary benzo[c]phenanthridine alkaloids.

Toxicology letters 20011215

Role of protein kinase C zeta isoform in Fas resistance of immature myeloid KG1a leukemic cells.

Blood 20011215

Mechanism of alpha-adrenergic regulation of expressed hKv4.3 currents.

American journal of physiology. Heart and circulatory physiology 20011201

Involvement of calcium, inositol-1,4,5 trisphosphate and diacylglycerol in the prothoracicotropic hormone-stimulated ecdysteroid synthesis and secretion in the prothoracic glands of Bombyx mori.

Zoological science 20011201

Role of protein kinase C in opioid modulation of glycine-gated Cl(-) current in rat periaqueductal gray neuron.

European journal of pharmacology 20011116

Adenosine A(2A) and A(2B) receptor activation of erythropoietin production.

American journal of physiology. Renal physiology 20011101

Mechanisms of the apoptotic and necrotic actions of trimethyltin in cerebellar granule cells.

Toxicological sciences : an official journal of the Society of Toxicology 20011101

Activation of PKC decreases myocardial O2 consumption and increases contractile efficiency in rats.

American journal of physiology. Heart and circulatory physiology 20011101

Differentiation of bipolar CG-4 line oligodendrocytes is associated with regulation of CREB, MAP kinase and PKC signalling pathways.

Neuroscience research 20011101

Role of spinal NMDA receptors, protein kinase C and nitric oxide synthase in the hyperalgesia induced by magnesium deficiency in rats.

British journal of pharmacology 20011101

Acute alcohol-induced protection against infarction in rabbit hearts: differences from and similarities to ischemic preconditioning.

Journal of molecular and cellular cardiology 20011101

Dual signaling via protein kinase C and phosphatidylinositol 3'-kinase/Akt contributes to bradykinin B2 receptor-induced cardioprotection in guinea pig hearts.

Journal of molecular and cellular cardiology 20011101

Regulation by endothelin-1 of Na+-Ca2+ exchange current (I(NaCa)) from guinea-pig isolated ventricular myocytes.

Cell calcium 20011101

Investigation of the inhibitory effects of chelerythrine chloride on the translocation of the protein kinase C betaI, betaII, zeta in human neutrophils.

Farmaco (Societa chimica italiana : 1989) 20011101

Mechanisms of Ca2+ overload induced by extracellular H2O2 in quiescent isolated rat cardiomyocytes.

Basic research in cardiology 20011101

Second messengers in platelet aggregation evoked by serotonin and A23187, a calcium ionophore.

Life sciences 20011026

Stimulatory effect of phenylephrine on the secretion of beta-endorphin from rat adrenal medulla in vitro.

Autonomic neuroscience : basic & clinical 20011008

Regulation and distribution of MAdCAM-1 in endothelial cells in vitro.

American journal of physiology. Cell physiology 20011001

Role of Na(+)/H(+) exchanger during O(2) deprivation in mouse CA1 neurons.

American journal of physiology. Cell physiology 20011001

Death by protein kinase C inhibitor: a stressful event.

Journal of molecular and cellular cardiology 20011001

Chelerythrine rapidly induces apoptosis through generation of reactive oxygen species in cardiac myocytes.

Journal of molecular and cellular cardiology 20011001

Protein kinase C regulation of cell spreading in the molluscan Biomphalaria glabrata embryonic (Bge) cell line.

Biochimica et biophysica acta 20010926

Protein kinase C regulates dopamine D4 receptor-mediated phospholipid methylation.

European journal of pharmacology 20010914

Induction of osteoblast differentiation indexes by PTHrP in MG-63 cells involves multiple signaling pathways.

American journal of physiology. Endocrinology and metabolism 20010901

Regulation of ATP-sensitive K(+) channels by protein kinase C in murine colonic myocytes.

American journal of physiology. Cell physiology 20010901

Src and multiple MAP kinase activation in cardiac hypertrophy and congestive heart failure under chronic pressure-overload: comparison with acute mechanical stretch.

Journal of molecular and cellular cardiology 20010901

The lysophospholipids sphingosine-1-phosphate and lysophosphatidic acid enhance survival during hypoxia in neonatal rat cardiac myocytes.

Journal of molecular and cellular cardiology 20010901

Inhibition of acetylcholine-activated K(+) current by chelerythrine and bisindolylmaleimide I in atrial myocytes from mice.

European journal of pharmacology 20010727

Chelerythrine and genistein inhibit the endothelin-1-induced increase in myofilament Ca(2+) sensitivity in rabbit ventricular myocytes.

European journal of pharmacology 20010720

Post-ischemic PKC inhibition impairs myocardial calcium handling and increases contractile protein calcium sensitivity.

Cardiovascular research 20010701

ANG II-mediated inhibition of neuronal delayed rectifier K+ current: role of protein kinase C-alpha.

American journal of physiology. Cell physiology 20010701

Heat shock prevents simulated ischemia-induced apoptosis in renal tubular cells via a PKC-dependent mechanism.

American journal of physiology. Regulatory, integrative and comparative physiology 20010701

Histamine increases interstitial adenosine concentration via activation of ecto-5'-nucleotidase in rat hearts in vivo.

The Journal of pharmacology and experimental therapeutics 20010701

Activation of extracellular signal-regulated kinase in trabecular meshwork cells.

Experimental eye research 20010701

Evidence for a role of protein kinase C in FGF signal transduction in the developing chick limb bud.

Development (Cambridge, England) 20010701

Inhibition of carbachol stimulated acid secretion by interleukin 1beta in rabbit parietal cells requires protein kinase C.

Gut 20010601

Capsaicin potentiates 1,25-dihydoxyvitamin D3- and all-trans retinoic acid-induced differentiation of human promyelocytic leukemia HL-60 cells.

European journal of pharmacology 20010525

Protein kinase C inhibition abrogates hepatic ischemic preconditioning responses.

The Journal of surgical research 20010515

17beta-oestradiol stimulates capacitative Ca2+ entry in human endometrial cells.

Molecular and cellular endocrinology 20010515

Protein kinase C regulation of dopamine transporter initiated by nicotinic receptor activation in slices of rat prefrontal cortex.

Journal of neurochemistry 20010501

Protein phosphorylation in mitochondria from human placenta.

Placenta 20010501

Characterisation using FLIPR of human vanilloid VR1 receptor pharmacology.

European journal of pharmacology 20010406

Ca2+-induced contraction of cat esophageal circular smooth muscle cells.

American journal of physiology. Cell physiology 20010401

Angiotensin II stimulates cardiac L-type Ca(2+) current by a Ca(2+)- and protein kinase C-dependent mechanism.

American journal of physiology. Heart and circulatory physiology 20010401

Antisense knockout of HOXB4 blocks 1,25-dihydroxyvitamin D3 inhibition of c-myc expression.

The Journal of endocrinology 20010401

Protein kinase C isoform-dependent modulation of ATP-sensitive K+ channels during reoxygenation in guinea-pig ventricular myocytes.

The Journal of physiology 20010401

Signalling pathways regulating the dephosphorylation of Ser729 in the hydrophobic domain of protein kinase Cepsilon upon cell passage.

The Journal of biological chemistry 20010330

Amplification effect and mechanism of action of ET-1 in U-46619-induced vasoconstriction in pig skin.

American journal of physiology. Regulatory, integrative and comparative physiology 20010301

Transgenic incorporation of skeletal TnT into cardiac myofilaments blunts PKC-mediated depression of force.

American journal of physiology. Heart and circulatory physiology 20010301

Essential activation of PKC-delta in opioid-initiated cardioprotection.

American journal of physiology. Heart and circulatory physiology 20010301

Exercise directly enhances myocardial tolerance to ischaemia-reperfusion injury in the rat through a protein kinase C mediated mechanism.

Heart (British Cardiac Society) 20010301

Use of protein kinase C inhibitors results in rapid [Mg(2+)](i) mobilization in primary cultured rat aortic smooth muscle cells: are certain kinase C isoforms natural homeostatic regulators of cystolic free Mg(2+).

European journal of pharmacology 20010216

Protection of cardiac myocytes via delta(1)-opioid receptors, protein kinase C, and mitochondrial K(ATP) channels.

American journal of physiology. Heart and circulatory physiology 20010101

Hemicholinium-3 mustard reveals two populations of cycling choline cotransporters in Limulus.

Neuroscience 20010101

Opioid receptor stimulation acts as mediator of protection in ischaemic preconditioning.

Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20010101

Interaction of benzo[c]phenanthridine and protoberberine alkaloids with animal and yeast cells.

Cell biology and toxicology 20010101

High calcium and dobutamine positive inotropy in the perfused mouse heart: myofilament calcium responsiveness, energetic economy, and effects of protein kinase C inhibition.

BMC physiology 20010101

Specificity and mechanism of action of some commonly used protein kinase inhibitors.

The Biochemical journal 20001001

Activation of potassium and chloride channels by tumor necrosis factor alpha. Role in liver cell death.

The Journal of biological chemistry 20000707

Effects of long-term nitroglycerin treatment on endothelial nitric oxide synthase (NOS III) gene expression, NOS III-mediated superoxide production, and vascular NO bioavailability.

Circulation research 20000107

Regulation of cytochrome P4501B1 (CYP1B1) in mouse embryo fibroblast (C3H10T1/2) cells by protein kinase C (PKC).

Biochemical pharmacology 19990315

Morphine preconditioning attenuates neutrophil activation in rat models of myocardial infarction.

Cardiovascular research 19981201

Protein kinase C activity is required for aryl hydrocarbon receptor pathway-mediated signal transduction.

Molecular pharmacology 19980401

Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase.

Journal of natural products 19910101

Aldosterone regulates rapid trafficking of epithelial sodium channel subunits in renal cortical collecting duct cells via protein kinase D activation.

Molecular endocrinology (Baltimore, Md.)

Androgens induce nongenomic stimulation of colonic contractile activity through induction of calcium sensitization and phosphorylation of LC20 and CPI-17.

Molecular endocrinology (Baltimore, Md.)

3895-92-9 | 1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridiniumchloride

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