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CAS No: 38819-10-2 Catalog No: AG0037XI MDL No:MFCD00065486
Title | Journal |
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Induction of fetal hemoglobin and ABCB1 gene expression in 9-β-D-arabinofuranosylguanine-resistant MOLT-4 cells. | Cancer chemotherapy and pharmacology 20110901 |
In vitro efficacy of forodesine and nelarabine (ara-G) in pediatric leukemia. | Blood 20110825 |
Activation of guanine-β-D-arabinofuranoside and deoxyguanosine to triphosphates by a common pathway blocks T lymphoblasts at different checkpoints. | Experimental cell research 20101210 |
A new high-performance liquid chromatography method determines low production of 9-beta-D-arabinofuranosylguanine triphosphate, an active metabolite of nelarabine, in adult T-cell leukemia cells. | Oncology reports 20100201 |
Intravitreal crystalline drug delivery for intraocular proliferation diseases. | Investigative ophthalmology & visual science 20100101 |
Nelarabine in the treatment of refractory T-cell malignancies. | Clinical Medicine Insights. Oncology 20100101 |
Acute cytotoxicity of arabinofuranosyl nucleoside analogs is not dependent on mitochondrial DNA. | Experimental cell research 20090910 |
Synthesis of 9-beta-d-arabinofuranosylguanine by combined use of two whole cell biocatalysts. | Bioorganic & medicinal chemistry letters 20090801 |
Profile of nelarabine: use in the treatment of T-cell acute lymphoblastic leukemia. | OncoTargets and therapy 20090101 |
Reduced levels of mitochondrial DNA increases the toxicity of 9-beta-D-arabinofuranosylguanine (araG). | Nucleosides, nucleotides & nucleic acids 20080601 |
Nelarabine. | Drugs 20080101 |
Role of nelarabine in the treatment of T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma. | Therapeutics and clinical risk management 20071201 |
Nelarabine: a novel purine antimetabolite antineoplastic agent. | Clinical therapeutics 20070901 |
Depletion of mitochondrial DNA by down-regulation of deoxyguanosine kinase expression in non-proliferating HeLa cells. | Experimental cell research 20070715 |
Nelarabine induces complete remissions in adults with relapsed or refractory T-lineage acute lymphoblastic leukemia or lymphoblastic lymphoma: Cancer and Leukemia Group B study 19801. | Blood 20070615 |
Cell cycle effect on the activity of deoxynucleoside analogue metabolising enzymes. | Biochemical and biophysical research communications 20070615 |
Plasma and cerebrospinal fluid pharmacokinetics of nelarabine in nonhuman primates. | Cancer chemotherapy and pharmacology 20070501 |
Novel selective human mitochondrial kinase inhibitors: design, synthesis and enzymatic activity. | Bioorganic & medicinal chemistry 20070415 |
Enhanced toxicity of purine nucleoside analogs in cells expressing Drosophila melanogaster nucleoside kinase mutants. | Gene therapy 20070101 |
Results of a phase II study of 506U78 in cutaneous T-cell lymphoma and peripheral T-cell lymphoma: CALGB 59901. | Leukemia & lymphoma 20070101 |
Nelarabine: a new purine analog in the treatment of hematologic malignancies. | Reviews on recent clinical trials 20060901 |
Nelarabine: efficacy in the treatment of clinical malignancies. | Future oncology (London, England) 20060801 |
Phosphorylation of 9-beta-D-arabinofuranosylguanine monophosphate by Drosophila melanogaster guanylate kinase. | Biochemical pharmacology 20051001 |
Phase II study of nelarabine (compound 506U78) in children and young adults with refractory T-cell malignancies: a report from the Children's Oncology Group. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050520 |
Phase I study of 506U78 administered on a consecutive 5-day schedule in children and adults with refractory hematologic malignancies. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050520 |
Structure-activity relationship of purine ribonucleosides for inhibition of hepatitis C virus RNA-dependent RNA polymerase. | Journal of medicinal chemistry 20040422 |
Anti-cowpox virus activities of certain adenosine analogs, arabinofuranosyl nucleosides, and 2'-fluoro-arabinofuranosyl nucleosides. | Nucleosides, nucleotides & nucleic acids 20040101 |
Mechanisms for T-cell selective cytotoxicity of arabinosylguanine. | Blood 20030901 |
The novel nucleoside transport system exhibited by NB4 cells, csg, transports deoxyguanosine analogues, including ara-G. | Biochemical pharmacology 20030901 |
Effects of 9-beta-D-arabinofuranosylguanine on mitochondria in CEM T-lymphoblast leukemia cells. | Biochemical and biophysical research communications 20030808 |
Cytosolic and mitochondrial deoxyribonucleotidases: activity with substrate analogs, inhibitors and implications for therapy. | Biochemical pharmacology 20030801 |
Resistance to mitochondrial- and Fas-mediated apoptosis in human leukemic cells with acquired resistance to 9-beta-D-arabinofuranosylguanosine. | Biochemical and biophysical research communications 20021101 |
Arabinosylguanine is phosphorylated by both cytoplasmic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. | Cancer research 20020601 |
Low level of mitochondrial deoxyguanosine kinase is the dominant factor in acquired resistance to 9-beta-D-arabinofuranosylguanine cytotoxicity. | Biochemical and biophysical research communications 20020524 |
Telomerase-inhibitory effects of sugar-modified nucleotide analogs. | Nucleic acids research. Supplement (2001) 20020101 |
Identification and characterization of human deoxyguanosine kinase cDNA fragments. | Cancer letters 20010920 |
Dual mechanisms of 9-beta-D-arabinofuranosylguanine resistance in CEM T-lymphoblast leukemia cells. | Biochemical and biophysical research communications 20010706 |
Nucleoside analogues: mechanisms of drug resistance and reversal strategies. | Leukemia 20010601 |
Anti-herpesvirus activity profile of 4'-thioarabinofuranosyl purine and uracil nucleosides and activity of 1-beta-D-2'-fluoro-4'-thioarabinofuranosyl guanine and 2,6-diaminopurine against clinical isolates of human cytomegalovirus. | Antiviral research 19980801 |
A facile, alternative synthesis of 4'-thioarabinonucleosides and their biological activities. | Journal of medicinal chemistry 19970704 |
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