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364-98-7 | diazoxide
CAS No: 364-98-7 Catalog No: AG0039DY MDL No:MFCD00078578
Product Description
Catalog Number:
AG0039DY
Chemical Name:
diazoxide
CAS Number:
364-98-7
Molecular Formula:
C8H7ClN2O2S
Molecular Weight:
230.6714
MDL Number:
MFCD00078578
IUPAC Name:
7-chloro-3-methyl-4H-1λ6,2,4-benzothiadiazine 1,1-dioxide
InChI:
InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)
InChI Key:
GDLBFKVLRPITMI-UHFFFAOYSA-N
SMILES:
Clc1ccc2c(c1)S(=O)(=O)NC(=N2)C
EC Number:
206-668-1
UNII:
O5CB12L4FN
Properties
Complexity:
360
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
229.992g/mol
Formal Charge:
0
Heavy Atom Count:
14
Hydrogen Bond Acceptor Count:
3
Hydrogen Bond Donor Count:
1
Isotope Atom Count:
0
Molecular Weight:
230.666g/mol
Monoisotopic Mass:
229.992g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
66.9A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.2
Literature
| Title | Journal |
|---|---|
| Conserved functional consequences of disease-associated mutations in the slide helix of Kir6.1 and Kir6.2 subunits of the ATP-sensitive potassium channel. | The Journal of biological chemistry 20171020 |
| Diazoxide prevents reactive oxygen species and mitochondrial damage, leading to anti-hypertrophic effects. | Chemico-biological interactions 20170105 |
| Mitochondrial Channel Opener Diazoxide Attenuates Hypoxia-Induced sFlt-1 Release in Human Choriocarcinoma Cells. | Journal of menopausal medicine 20140401 |
| Combined contributions of over-secreted glucagon-like peptide 1 and suppressed insulin secretion to hyperglycemia induced by gatifloxacin in rats. | Toxicology and applied pharmacology 20130201 |
| Expression and regulation of nampt in human islets. | PloS one 20130101 |
| Skeletal muscle post-conditioning by diazoxide, anti-oxidative and anti-apoptotic mechanisms. | Molecular biology reports 20121201 |
| Mechanisms of antihyperglycaemic action of efaroxan in mice: time for reappraisal of α2A-adrenergic antagonism in the treatment of type 2 diabetes? | Diabetologia 20121101 |
| Diabetes triggers a PARP1 mediated death pathway in the heart through participation of FoxO1. | Journal of molecular and cellular cardiology 20121101 |
| Octreotide for the treatment of sulfonylurea poisoning. | Clinical toxicology (Philadelphia, Pa.) 20121101 |
| Late anti-apoptotic effect of K(ATP) channel opening in skeletal muscle. | Clinical and experimental pharmacology & physiology 20121101 |
| Agelaia MP-I: a peptide isolated from the venom of the social wasp, Agelaia pallipes pallipes, enhances insulin secretion in mice pancreatic islets. | Toxicon : official journal of the International Society on Toxinology 20120915 |
| Prostatic relaxation induced by agmatine is decreased in spontaneously hypertensive rats. | BJU international 20120901 |
| Effects of Aβ1‐42 on the current of KATP channels in cultured cholinergic neurons. | Neurological research 20120901 |
| Mitochondrial ROMK channel is a molecular component of mitoK(ATP). | Circulation research 20120803 |
| Synthesis and pharmacological activity of N-(2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-4-yl)-4H-1,2,4-benzothiadiazine-3-carboxamides 1,1-dioxides on rat uterus, rat aorta and rat pancreatic β-cells. | European journal of medicinal chemistry 20120801 |
| Intractable absence seizures in hyperinsulinism-hyperammonemia syndrome. | Pediatric neurology 20120801 |
| Effects of mitochondrial ATP-sensitive K(+) channel on protein kinase C pathway and airway smooth muscle cell proliferation in asthma. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20120801 |
| Nuciferine stimulates insulin secretion from beta cells-an in vitro comparison with glibenclamide. | Journal of ethnopharmacology 20120713 |
| Successful control of intractable hypoglycemia using radiopharmaceutical therapy with strontium-89 in a case with malignant insulinoma and bone metastases. | Japanese journal of clinical oncology 20120701 |
| Mitochondrial K+ channels are involved in ischemic postconditioning in rat hearts. | The journal of physiological sciences : JPS 20120701 |
| Enhancement of liver regeneration by adenosine triphosphate-sensitive K⁺ channel opener (diazoxide) after partial hepatectomy. | Transplantation 20120615 |
| The regulation of K- and L-cell activity by GLUT2 and the calcium-sensing receptor CasR in rat small intestine. | The Journal of physiology 20120615 |
| Role of connexin-43 in protective PI3K-Akt-GSK-3β signaling in cardiomyocytes. | American journal of physiology. Heart and circulatory physiology 20120615 |
| Nutrient detection by incretin hormone secreting cells. | Physiology & behavior 20120606 |
| Diazoxide inhibits aortic endothelial cell apoptosis in diabetic rats via activation of ERK. | Acta diabetologica 20120601 |
| Quantitative pancreatic β cell MRI using manganese-enhanced Look-Locker imaging and two-site water exchange analysis. | Magnetic resonance in medicine 20120601 |
| Protective effects of diazoxide against Aβ₂₅₋₃₅-induced PC12 cell apoptosis due to prevention of endoplasmic reticulum stress. | Neuroreport 20120530 |
| Two neonatal diabetes mutations on transmembrane helix 15 of SUR1 increase affinity for ATP and ADP at nucleotide binding domain 2. | The Journal of biological chemistry 20120525 |
| Glucose-mediated control of ghrelin release from primary cultures of gastric mucosal cells. | American journal of physiology. Endocrinology and metabolism 20120515 |
| Partial ABCC8 gene deletion mutations causing diazoxide-unresponsive hyperinsulinaemic hypoglycaemia. | Pediatric diabetes 20120501 |
| Protective effect of delayed remote limb ischemic postconditioning: role of mitochondrial K(ATP) channels in a rat model of focal cerebral ischemic reperfusion injury. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120501 |
| Polysaccharide isolated from Triticum aestivum stimulates insulin release from pancreatic cells via the ATP-sensitive K+ channel. | International journal of molecular medicine 20120501 |
| Prolonged successful therapy for hyperinsulinaemic hypoglycaemia after gastric bypass: the pathophysiological role of GLP1 and its response to a somatostatin analogue. | European journal of endocrinology 20120501 |
| A new mitochondrial pH biosensor for quantitative assessment of pancreatic β-cell function. | Biochemical and biophysical research communications 20120427 |
| Diazoxide attenuates ischemia/reperfusion injury via upregulation of heme oxygenase-1 after liver transplantation in rats. | World journal of gastroenterology 20120421 |
| Mice expressing a human K(ATP) channel mutation have altered channel ATP sensitivity but no cardiac abnormalities. | Diabetologia 20120401 |
| Diazoxide pretreatment enhances L6 skeletal myoblast survival and inhibits apoptosis induced by hydrogen peroxide. | Anatomical record (Hoboken, N.J. : 2007) 20120401 |
| Anesthetic management of a 6 month-old infant for near total pancreatectomy with persistent hyperinsulinemic hypoglycemia. | Korean journal of anesthesiology 20120401 |
| Protein phosphorylation involved in the gene expression of the hydrogen sulphide producing enzyme cystathionine γ-lyase in the pancreatic β-cell. | Molecular and cellular endocrinology 20120305 |
| Role of the amino-terminal transmembrane domain of sulfonylurea receptor SUR2B for coupling to K(IR)6.2, ligand binding, and oligomerization. | Naunyn-Schmiedeberg's archives of pharmacology 20120301 |
| Some cannabinoid receptor ligands and their distomers are direct-acting openers of SUR1 K(ATP) channels. | American journal of physiology. Endocrinology and metabolism 20120301 |
| Regulation of calcium in pancreatic α- and β-cells in health and disease. | Cell calcium 20120301 |
| Glucose-induced nuclear shuttling of ChREBP is mediated by sorcin and Ca(2+) ions in pancreatic β-cells. | Diabetes 20120301 |
| Ethanol causes endoplasmic reticulum stress and impairment of insulin secretion in pancreatic β-cells. | Alcohol (Fayetteville, N.Y.) 20120201 |
| Successful treatment of congenital hyperinsulinism with long-acting release octreotide. | European journal of endocrinology 20120201 |
| Disruption and stabilization of β-cell actin microfilaments differently influence insulin secretion triggered by intracellular Ca2+ mobilization or store-operated Ca2+ entry. | FEBS letters 20120102 |
| Mitochondrial calcium homeostasis as potential target for mitochondrial medicine. | Mitochondrion 20120101 |
| The heterogeneity of focal forms of congenital hyperinsulinism. | The Journal of clinical endocrinology and metabolism 20120101 |
| Guidelines for the management of gastroenteropancreatic neuroendocrine (including carcinoid) tumours (NETs). | Gut 20120101 |
| US-guided ethanol ablation of insulinomas: a new treatment option. | Gastrointestinal endoscopy 20120101 |
| Non-classic androgen actions in Sertoli cell membrane in whole seminiferous tubules: effects of nandrolone decanoate and catechin. | Steroids 20120101 |
| K(ATP) channel openers in the trigeminovascular system. | Cephalalgia : an international journal of headache 20120101 |
| Activation of IL-11/STAT3 pathway in preconditioned human skeletal myoblasts blocks apoptotic cascade under oxidant stress. | Regenerative medicine 20120101 |
| Glucose-induced O₂ consumption activates hypoxia inducible factors 1 and 2 in rat insulin-secreting pancreatic beta-cells. | PloS one 20120101 |
| Hyperglycemia raises the threshold of levosimendan- but not milrinone-induced postconditioning in rat hearts. | Cardiovascular diabetology 20120101 |
| Increase of ATP-sensitive potassium (K(ATP)) channels in the heart of type-1 diabetic rats. | Cardiovascular diabetology 20120101 |
| Acute and chronic animal models for the evaluation of anti-diabetic agents. | Cardiovascular diabetology 20120101 |
| Reactive oxygen species stimulate insulin secretion in rat pancreatic islets: studies using mono-oleoyl-glycerol. | PloS one 20120101 |
| Rapid insulinotropic action of low doses of bisphenol-A on mouse and human islets of Langerhans: role of estrogen receptor β. | PloS one 20120101 |
| High-dose fasudil preserves postconditioning against myocardial infarction under hyperglycemia in rats: role of mitochondrial KATP channels. | Cardiovascular diabetology 20120101 |
| The diabetic heart: too sweet for its own good? | Cardiology research and practice 20120101 |
| Effects of Extract from Solid-State Fermented Cordyceps sinensis on Type 2 Diabetes Mellitus. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| Nicorandil attenuates monocrotaline-induced vascular endothelial damage and pulmonary arterial hypertension. | PloS one 20120101 |
| Insulinotropic effect of the non-steroidal compound STX in pancreatic β-cells. | PloS one 20120101 |
| Metoclopramide-induced oculogyric crisis presenting as encephalitis in a young girl. | Indian journal of pharmacology 20120101 |
| Hyperinsulinism presenting in childhood and treatment by conservative pancreatectomy. | Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20120101 |
| [Effects of diazoxide on the mitochondrial membrane potential and ROS generation in rat uterus cells]. | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20120101 |
| Localized acquired hypertrichosis associated with the application of a splint. | Case reports in pediatrics 20120101 |
| Prostatic relaxation induced by loperamide is reduced in spontaneously hypertensive rats. | TheScientificWorldJournal 20120101 |
| Bariatric surgery in hypothalamic obesity. | Frontiers in endocrinology 20120101 |
| Insulinoma and anaesthetic implications. | Indian journal of anaesthesia 20120101 |
| Towards therapeutic applications of arthropod venom k(+)-channel blockers in CNS neurologic diseases involving memory acquisition and storage. | Journal of toxicology 20120101 |
| Ficus deltoidea: A Potential Alternative Medicine for Diabetes Mellitus. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| Expression of transient receptor potential ankyrin 1 (TRPA1) and its role in insulin release from rat pancreatic beta cells. | PloS one 20120101 |
| Primary aldosteronism in pregnancy. | Acta clinica Belgica 20120101 |
| Echocardiography monitoring for diazoxide induced pericardial effusion. | BMJ case reports 20120101 |
| Drug-induced hepatitis following use of octreotide for long-term treatment of congenital hyperinsulinism. | BMJ case reports 20120101 |
| Paclitaxel-induced endothelial dysfunction in living rats is prevented by nicorandil via reduction of oxidative stress. | Journal of pharmacological sciences 20120101 |
| Seizure due to somatostatin analog discontinuation in a case diagnosed as congenital hyperinsulinism novel mutation. | Journal of pediatric endocrinology & metabolism : JPEM 20120101 |
| [Neuroprotective effect of ischemic postconditioning and remote preconditioning. Prospective of clinical use]. | Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20120101 |
| Cardiac subsarcolemmal and interfibrillar mitochondria display distinct responsiveness to protection by diazoxide. | PloS one 20120101 |
| The effect of tempol administration on the aortic contractile responses in rat preeclampsia model. | ISRN pharmacology 20120101 |
| Aquaporin-7 expression during coronary artery bypass grafting with diazoxide. | Scandinavian cardiovascular journal : SCJ 20111201 |
| Protective effect of diazoxide against antimycin A-induced mitochondrial dysfunction in osteoblastic MC3T3-E1 cells. | Toxicology in vitro : an international journal published in association with BIBRA 20111201 |
| Inhibition of 5-lipoxygenase triggers apoptosis in prostate cancer cells via down-regulation of protein kinase C-epsilon. | Biochimica et biophysica acta 20111201 |
| Rapid functional evaluation of beta-cells by extracellular recording of membrane potential oscillations with microelectrode arrays. | Pflugers Archiv : European journal of physiology 20111201 |
| Morphological mosaicism of the pancreatic islets: a novel anatomopathological form of persistent hyperinsulinemic hypoglycemia of infancy. | The Journal of clinical endocrinology and metabolism 20111201 |
| Potential candidate genomic biomarkers of drug induced vascular injury in the rat. | Toxicology and applied pharmacology 20111201 |
| Unique properties of the ATP-sensitive K⁺ channel in the mouse ventricular cardiac conduction system. | Circulation. Arrhythmia and electrophysiology 20111201 |
| Activation of K(ATP) channels suppresses glucose production in humans. | The Journal of clinical investigation 20111201 |
| Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
| Inhibitors of succinate: quinone reductase/Complex II regulate production of mitochondrial reactive oxygen species and protect normal cells from ischemic damage but induce specific cancer cell death. | Pharmaceutical research 20111101 |
| Improved control of severe hypoglycemia in patients with malignant insulinomas by peptide receptor radionuclide therapy. | The Journal of clinical endocrinology and metabolism 20111101 |
| Rapid signaling responses in Sertoli cell membranes induced by follicle stimulating hormone and testosterone: calcium inflow and electrophysiological changes. | Life sciences 20111010 |
| Lessons in human biology from a monogenic pancreatic β cell disease. | The Journal of clinical investigation 20111003 |
| In vitro insulin secretion by pancreatic tissue from infants with diazoxide-resistant congenital hyperinsulinism deviates from model predictions. | The Journal of clinical investigation 20111003 |
| Treatment with somatostatin analogs and chemoembolization of liver metastases for severe hypoglycemia in malignant insulinomas. | Journal of endocrinological investigation 20111001 |
| Advances in the etiology and management of hyperinsulinemic hypoglycemia after Roux-en-Y gastric bypass. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20111001 |
| Hyperinsulinaemic hypoglycaemia and diabetes mellitus due to dominant ABCC8/KCNJ11 mutations. | Diabetologia 20111001 |
| Mechanisms involved in the desflurane-induced post-conditioning of isolated human right atria from patients with type 2 diabetes. | British journal of anaesthesia 20111001 |
| Mechanisms of control of the free Ca2+ concentration in the endoplasmic reticulum of mouse pancreatic β-cells: interplay with cell metabolism and [Ca2+]c and role of SERCA2b and SERCA3. | Diabetes 20111001 |
| Positional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion. | PLoS genetics 20111001 |
| Mechanisms of p-methoxycinnamic acid-induced increase in insulin secretion. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20111001 |
| Genome protective effect of metformin as revealed by reduced level of constitutive DNA damage signaling. | Aging 20111001 |
| Isoflurane decreases death of human embryonic stem cell-derived, transcriptional marker Nkx2.5(+) cardiac progenitor cells. | Acta anaesthesiologica Scandinavica 20111001 |
| Glitazone-like action of glimepiride and glibenclamide in primary human adipocytes. | Diabetes, obesity & metabolism 20110901 |
| Subsecond regulation of striatal dopamine release by pre-synaptic KATP channels. | Journal of neurochemistry 20110901 |
| Diazoxide decreases ischemia-reperfusion injury in a rat model of lung transplantation. | Transplantation proceedings 20110901 |
| Characterization of an ATP-sensitive K(+) channel in rat carotid body glomus cells. | Respiratory physiology & neurobiology 20110815 |
| Diazoxide suppresses hepatic ischemia/reperfusion injury after mouse liver transplantation by a BCL-2-dependent mechanism. | The Journal of surgical research 20110801 |
| Interaction of morphine and potassium channel openers on experimental models of pain in mice. | Fundamental & clinical pharmacology 20110801 |
| Current and future drug targets in weight management. | Pharmaceutical research 20110801 |
| Effects of KATP channel openers diazoxide and pinacidil in coronary-perfused atria and ventricles from failing and non-failing human hearts. | Journal of molecular and cellular cardiology 20110801 |
| Heat shock protein 90 mediates anti-apoptotic effect of diazoxide by preventing the cleavage of Bid in hypothermic preservation rat hearts. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20110801 |
| Severity of diabetes governs vascular lipoprotein lipase by affecting enzyme dimerization and disassembly. | Diabetes 20110801 |
| Treatment of congenital hyperinsulinism with lanreotide acetate (Somatuline Autogel). | The Journal of clinical endocrinology and metabolism 20110801 |
| ATP-sensitive potassium (KATP) channel activation decreases intraocular pressure in the anterior chamber of the eye. | Investigative ophthalmology & visual science 20110801 |
| [The effect of 5-HD on expression of PKC-alpha in rats of chronic hypoxic pulmonary hypertension]. | Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20110801 |
| The effect of adrenergic β(2) receptor agonist on paraplegia following clamping of abdominal aorta. | Archives of medical science : AMS 20110801 |
| Glucose regulates free cytosolic Zn²⁺ concentration, Slc39 (ZiP), and metallothionein gene expression in primary pancreatic islet β-cells. | The Journal of biological chemistry 20110722 |
| Type-specific human papillomavirus detection in cervical smears in Romania. | APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20110701 |
| Exendin-4 increases islet amyloid deposition but offsets the resultant beta cell toxicity in human islet amyloid polypeptide transgenic mouse islets. | Diabetologia 20110701 |
| Ontogeny of sulfonylurea-binding regulatory subunits of K(ATP) channels in the pregnant rat myometrium. | Reproduction (Cambridge, England) 20110701 |
| Modulation of the 6-position of benzopyran derivatives and inhibitory effects on the insulin releasing process. | Bioorganic & medicinal chemistry 20110701 |
| Glucosensing in parvocellular neurons of the rat hypothalamic paraventricular nucleus. | The European journal of neuroscience 20110701 |
| Dominantly acting ABCC8 mutations in patients with medically unresponsive hyperinsulinaemic hypoglycaemia. | Clinical genetics 20110601 |
| The role of oxidized cytochrome c in regulating mitochondrial reactive oxygen species production and its perturbation in ischaemia. | The Biochemical journal 20110601 |
| Characterization of ABCC8 and KCNJ11 gene mutations and phenotypes in Korean patients with congenital hyperinsulinism. | European journal of endocrinology 20110601 |
| Mitochondrial KATP channels participate in the limitation of infarct size by cariporide. | Naunyn-Schmiedeberg's archives of pharmacology 20110601 |
| Diazoxide-unresponsive congenital hyperinsulinism in children with dominant mutations of the β-cell sulfonylurea receptor SUR1. | Diabetes 20110601 |
| Adenosine triphosphate-sensitive potassium channel blockers attenuate the antiallodynic effect of R-PIA in neuropathic rats. | Anesthesia and analgesia 20110601 |
| Mutations of the same conserved glutamate residue in NBD2 of the sulfonylurea receptor 1 subunit of the KATP channel can result in either hyperinsulinism or neonatal diabetes. | Diabetes 20110601 |
| [Protective effects of mitochondrial ATP-sensitive potassium channel on A549 cell apoptosis induced by hyperoxia]. | Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20110601 |
| Diazoxide preconditioning against seizure-induced oxidative injury is via the PI3K/Akt pathway in epileptic rat. | Neuroscience letters 20110516 |
| Impact of the nature of the substituent at the 3-position of 4H-1,2,4-benzothiadiazine 1,1-dioxides on their opening activity toward ATP-sensitive potassium channels. | Journal of medicinal chemistry 20110512 |
| Hypertensive emergencies in children. | Indian journal of pediatrics 20110501 |
| Bioenergetic defect associated with mKATP channel opening in a mouse model carrying a mitofusin 2 mutation. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110501 |
| The vasorelaxant effect of hydrogen sulfide is enhanced in streptozotocin-induced diabetic rats. | Naunyn-Schmiedeberg's archives of pharmacology 20110501 |
| Sex differences in the contribution of ATP-sensitive K+ channels in trigeminal ganglia under an acute muscle pain condition. | Neuroscience 20110428 |
| Nucleo-cytosolic shuttling of FoxO1 directly regulates mouse Ins2 but not Ins1 gene expression in pancreatic beta cells (MIN6). | The Journal of biological chemistry 20110415 |
| Role of PI3K/Akt in diazoxide preconditioning against rat hippocampal neuronal death in pilocarpine-induced seizures. | Brain research 20110406 |
| GSK-3β at the crossroads in the signalling of heart preconditioning: implication of mTOR and Wnt pathways. | Cardiovascular research 20110401 |
| Treat the graft to improve the regenerative ability of the host. | Medical hypotheses 20110401 |
| Glucose-dependent changes in SNARE protein levels in pancreatic β-cells. | Endocrinology 20110401 |
| Partial inhibition of insulin secretion results in glucose intolerance but not hyperglucagonemia. | Diabetes 20110401 |
| In vitro recovery of ATP-sensitive potassium channels in β-cells from patients with congenital hyperinsulinism of infancy. | Diabetes 20110401 |
| Congenital hyperinsulinism: review of 12 Tunisian cases. | La Tunisie medicale 20110401 |
| Transient neonatal hyperinsulinemic hypoglycemia and neurological outcome: a case report. | Minerva pediatrica 20110401 |
| KCa2 channels activation prevents [Ca2+]i deregulation and reduces neuronal death following glutamate toxicity and cerebral ischemia. | Cell death & disease 20110401 |
| Pancreatic endocrine tumors. | North American journal of medical sciences 20110401 |
| The protective roles of mitochondrial ATP-sensitive potassium channels during hypoxia-ischemia-reperfusion in brain. | Neuroscience letters 20110310 |
| Functional role of the activity of ATP-sensitive potassium channels in electrical behavior of hippocampal neurons: experimental and theoretical studies. | Journal of theoretical biology 20110307 |
| [Malignant insulinoma]. | Orvosi hetilap 20110306 |
| Hyperinsulinemic hypoglycemia associated with ectopic Cushing's syndrome due to a pancreatic endocrine tumor in a Type 2 diabetes mellitus patient: clinical implications of a rare association. | Journal of endocrinological investigation 20110301 |
| Inhibition of gastric motility by hyperglycemia is mediated by nodose ganglia KATP channels. | American journal of physiology. Gastrointestinal and liver physiology 20110301 |
| Genome-wide homozygosity analysis reveals HADH mutations as a common cause of diazoxide-responsive hyperinsulinemic-hypoglycemia in consanguineous pedigrees. | The Journal of clinical endocrinology and metabolism 20110301 |
| Synthesis and biological evaluation of 5-membered spiro heterocycle-benzopyran derivatives against myocardial ischemia. | European journal of medicinal chemistry 20110301 |
| Postconditioning in focal cerebral ischemia: role of the mitochondrial ATP-dependent potassium channel. | Brain research 20110223 |
| Induction of insulin secretion by an aqueous extract of Tabernanhte iboga Baill. (Apocynaceae) in rat pancreatic islets of Langerhans. | Journal of ethnopharmacology 20110216 |
| Interactive medical case. Lying low. | The New England journal of medicine 20110210 |
| Recognition of sulfonylurea receptor (ABCC8/9) ligands by the multidrug resistance transporter P-glycoprotein (ABCB1): functional similarities based on common structural features between two multispecific ABC proteins. | The Journal of biological chemistry 20110204 |
| Levosimendan modulates programmed forms of cell death through K(ATP) channels and nitric oxide. | Journal of cardiovascular pharmacology 20110201 |
| Genetics of congenital hyperinsulinemic hypoglycemia. | Seminars in pediatric surgery 20110201 |
| KATP channel mutations in congenital hyperinsulinism. | Seminars in pediatric surgery 20110201 |
| A specialized team approach to diagnosis and medical versus surgical treatment of infants with congenital hyperinsulinism. | Seminars in pediatric surgery 20110201 |
| Rare forms of congenital hyperinsulinism. | Seminars in pediatric surgery 20110201 |
| Glutamine triggers and potentiates glucagon-like peptide-1 secretion by raising cytosolic Ca2+ and cAMP. | Endocrinology 20110201 |
| Role of vascular K(ATP) channels in blood pressure variability after sinoaortic denervation in rats. | Acta pharmacologica Sinica 20110201 |
| Effect of glibenclamide on antinociceptive effects of antidepressants of different classes. | Clinics (Sao Paulo, Brazil) 20110201 |
| AIF-mediated mitochondrial pathway is critical for the protective effect of diazoxide against SH-SY5Y cell apoptosis. | Brain research 20110125 |
| Diazoxide attenuates indomethacin-induced small intestinal damage in the rat. | European journal of pharmacology 20110110 |
| The pancreas in human type 1 diabetes. | Seminars in immunopathology 20110101 |
| Reversal of rotenone-induced dysfunction of astrocytic connexin43 by opening mitochondrial ATP-sensitive potassium channels. | Cellular and molecular neurobiology 20110101 |
| Lack of TRPM2 impaired insulin secretion and glucose metabolisms in mice. | Diabetes 20110101 |
| Familial focal congenital hyperinsulinism. | The Journal of clinical endocrinology and metabolism 20110101 |
| Congenital hyperinsulinism and glucose hypersensitivity in homozygous and heterozygous carriers of Kir6.2 (KCNJ11) mutation V290M mutation: K(ATP) channel inactivation mechanism and clinical management. | Diabetes 20110101 |
| Cardiac glycosides are potent inhibitors of interferon-β gene expression. | Nature chemical biology 20110101 |
| Isoflurane preconditioning increases endothelial cell tolerance to in-vitro simulated ischaemia. | The Journal of pharmacy and pharmacology 20110101 |
| Elimination of hypoglycemia from the lives of people affected by diabetes. | Diabetes 20110101 |
| TRP-ing down the path to insulin secretion. | Diabetes 20110101 |
| Everolimus resolving hypoglycemia, producing hyperglycemia, and necessitating insulin use in a patient with diabetes and nonresectable malignant insulinoma. | Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20110101 |
| Metastatic insulinoma in a patient with type 2 diabetes mellitus: case report and review of the literature. | International journal of endocrinology 20110101 |
| Continuous glucose monitoring for evaluation of glycemic excursions after gastric bypass. | Journal of obesity 20110101 |
| New developments in the treatment of hyperammonemia: emerging use of carglumic acid. | International journal of general medicine 20110101 |
| Molecular mechanisms in exercise-induced cardioprotection. | Cardiology research and practice 20110101 |
| Expression of ATP-sensitive potassium channels in human pregnant myometrium. | Reproductive biology and endocrinology : RB&E 20110101 |
| Regulation of gap junctional communication by astrocytic mitochondrial K(ATP) channels following neurotoxin administration in in vitro and in vivo models. | Neuro-Signals 20110101 |
| Evidence for presence and functional effects of Kv1.1 channels in β-cells: general survey and results from mceph/mceph mice. | PloS one 20110101 |
| Nateglinide stimulates glucagon-like peptide-1 release by human intestinal L cells via a K(ATP) channel-independent mechanism. | Biological & pharmaceutical bulletin 20110101 |
| Role of the nitric oxide on relaxation of the human umbilical artery during cooling. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110101 |
| Cardioprotective effect of nicorandil, a mitochondrial ATP-sensitive potassium channel opener, prolongs survival in HSPB5 R120G transgenic mice. | PloS one 20110101 |
| Mitochondrial approaches to protect against cardiac ischemia and reperfusion injury. | Frontiers in physiology 20110101 |
| Activation of ATP-sensitive potassium channels antagonize nociceptive behavior and hyperexcitability of DRG neurons from rats. | Molecular pain 20110101 |
| Pharmacological modulation of dopamine receptor D2-mediated transmission alters the metabolic phenotype of diet induced obese and diet resistant C57Bl6 mice. | Experimental diabetes research 20110101 |
| Hypothalamic Obesity following Craniopharyngioma Surgery: Results of a Pilot Trial of Combined Diazoxide and Metformin Therapy. | International journal of pediatric endocrinology 20110101 |
| Role of Kv1 potassium channels in regulating dopamine release and presynaptic D2 receptor function. | PloS one 20110101 |
| MicroRNAs in cardiovascular disease. | F1000 medicine reports 20110101 |
| Evolving diagnostic and treatment strategies for pancreatic neuroendocrine tumors. | Journal of hematology & oncology 20110101 |
| Preconditioning involves selective mitophagy mediated by Parkin and p62/SQSTM1. | PloS one 20110101 |
| Modulation of myocardial mitochondrial mechanisms during severe polymicrobial sepsis in the rat. | PloS one 20110101 |
| Lack of Restoration in Vivo by K-Channel Modulators of Jejunal Fluid Absorption after Heat Stable Escherichia coli Enterotoxin (STa) Challenge. | Journal of tropical medicine 20110101 |
| Hypoglycemic syndrome in a patient with proinsulin-only secreting pancreatic adenoma (proinsulinoma). | Case reports in medicine 20110101 |
| Stem cells for cardiac repair: status, mechanisms, and new strategies. | Stem cells international 20110101 |
| Analysis of mitochondrial 3D-deformation in cardiomyocytes during active contraction reveals passive structural anisotropy of orthogonal short axes. | PloS one 20110101 |
| Octreotide-treated diabetes accompanied by endogenous hyperinsulinemic hypoglycemia and protein-losing gastroenteropathy. | Case reports in medicine 20110101 |
| [Congenital hyperinsulinism in the north-east Netherlands. Clinical features and DNA diagnostics in 22 children]. | Nederlands tijdschrift voor geneeskunde 20110101 |
| ATP-Sensitive Potassium Channel Currents in Eccentrically Hypertrophied Cardiac Myocytes of Volume-Overloaded Rats. | International journal of cell biology 20110101 |
| [The influence of ATP-dependent K(+)-channel diazoxide opener on the opening of mitochondrial permeability transition pore in rat liver mitochondria]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20110101 |
| [Regulation of the mitochondrial ATP-sensitive potassium channel in rat uterus cells by ROS]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20110101 |
| Control of the intracellular redox state by glucose participates in the insulin secretion mechanism. | PloS one 20110101 |
| Pulmonary hypertension and reopening of the ductus arteriosus in an infant treated with diazoxide. | Journal of pediatric endocrinology & metabolism : JPEM 20110101 |
| Short- and long-term physiologic and pharmacologic control of blood pressure in pediatric patients. | Integrated blood pressure control 20110101 |
| Congenital hyperinsulinism: current trends in diagnosis and therapy. | Orphanet journal of rare diseases 20110101 |
| High-throughput assay for the identification of compounds regulating osteogenic differentiation of human mesenchymal stromal cells. | PloS one 20110101 |
| Oral administration of the KATP channel opener diazoxide ameliorates disease progression in a murine model of multiple sclerosis. | Journal of neuroinflammation 20110101 |
| MiR-146a in Immunity and Disease. | Molecular biology international 20110101 |
| Nicorandil prevents endothelial dysfunction due to antioxidative effects via normalisation of NADPH oxidase and nitric oxide synthase in streptozotocin diabetic rats. | Cardiovascular diabetology 20110101 |
| Hyperinsulinism associated with gestational exposure to bupropion in a newborn infant. | Journal of pediatric endocrinology & metabolism : JPEM 20110101 |
| Measurement of warfarin in the oral fluid of patients undergoing anticoagulant oral therapy. | PloS one 20110101 |
| [Ontogeny of sulphonylurea-binding regulatory subunits of K(ATP) channels in the pregnant rat myometrium]. | Acta pharmaceutica Hungarica 20110101 |
| Clinical characteristics of recessive and dominant congenital hyperinsulinism due to mutation(s) in the ABCC8/KCNJ11 genes encoding the ATP-sensitive potasium channel in the pancreatic beta cell. | Journal of pediatric endocrinology & metabolism : JPEM 20110101 |
| Long term sequelae of pediatric craniopharyngioma - literature review and 20 years of experience. | Frontiers in endocrinology 20110101 |
| Effects of methylphenidate on weight gain and food intake in hypothalamic obesity. | Frontiers in endocrinology 20110101 |
| Hypothalamic obesity after craniopharyngioma: mechanisms, diagnosis, and treatment. | Frontiers in endocrinology 20110101 |
| Paternal Uniparental Isodisomy of Chromosome 11p15.5 within the Pancreas Causes Isolated Hyperinsulinemic Hypoglycemia. | Frontiers in endocrinology 20110101 |
| Neonatal hyperinsulinism secondary to maternal intake of high-sugar drinks. | BMJ case reports 20110101 |
| Rapidly progressing malignant insulinoma presented with multiple liver metastases: a case report. | Journal of gastrointestinal cancer 20101201 |
| Diazoxide attenuates hypothermic preservation-induced renal injury via down-regulation of CHOP and caspase-12. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101201 |
| Both mitochondrial KATP channel opening and sarcolemmal KATP channel blockage confer protection against ischemia/reperfusion-induced arrhythmia in anesthetized male rats. | Journal of cardiovascular pharmacology and therapeutics 20101201 |
| Adenosine A(1) and A (3) receptor agonists reduce hypoxic injury through the involvement of P38 MAPK. | Molecular and cellular biochemistry 20101201 |
| Role of KATP and L-type Ca2+ channel activities in regulation of ovine uterine vascular contractility: effect of pregnancy and chronic hypoxia. | American journal of obstetrics and gynecology 20101201 |
| Myocardial ischaemic and diazoxide preconditioning both increase PGC-1alpha and reduce mitochondrial damage. | Acta cardiologica 20101201 |
| Hyperinsulinemic hypoglycemia evolving to gestational diabetes and diabetes mellitus in a family carrying the inactivating ABCC8 E1506K mutation. | Pediatric diabetes 20101101 |
| Pharmacological preconditioning by diazoxide downregulates cardiac L-type Ca(2+) channels. | British journal of pharmacology 20101101 |
| Discrimination between two possible reaction sequences that create potential risk of generation of deleterious radicals by cytochrome bc₁. Implications for the mechanism of superoxide production. | Biochimica et biophysica acta 20101101 |
| ABCC8 and KCNJ11 molecular spectrum of 109 patients with diazoxide-unresponsive congenital hyperinsulinism. | Journal of medical genetics 20101101 |
| Roles of phospho-GSK-3β in myocardial protection afforded by activation of the mitochondrial K ATP channel. | Journal of molecular and cellular cardiology 20101101 |
| Management of intractable hypoglycemia with Yttirum-90 radioembolization in a patient with malignant insulinoma. | The American journal of the medical sciences 20101101 |
| Hypoglycaemia following gastric bypass surgery--diabetes remission in the extreme? | Diabetologia 20101101 |
| Diazoxide maintenance of myocyte volume and contractility during stress: evidence for a non-sarcolemmal K(ATP) channel location. | The Journal of thoracic and cardiovascular surgery 20101101 |
| Microfluidic multi-analyte gradient generator. | Analytical and bioanalytical chemistry 20101101 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| 3-(6-Fluoro-4-oxo-4H-chromen-3-yl)-3,4-dihydro-2H-1,2,4-benzothia-diazine-1,1-dione. | Acta crystallographica. Section E, Structure reports online 20101101 |
| Mechanisms of the beneficial actions of ischemic preconditioning on subcellular remodeling in ischemic-reperfused heart. | Current cardiology reviews 20101101 |
| Management of postgastric bypass noninsulinoma pancreatogenous hypoglycemia. | Surgical endoscopy 20101001 |
| Mitochondrial cyclophilin-D as a critical mediator of ischaemic preconditioning. | Cardiovascular research 20101001 |
| Endothelin signalling regulates volume-sensitive Cl- current via NADPH oxidase and mitochondrial reactive oxygen species. | Cardiovascular research 20101001 |
| MicroRNA-21 is a key determinant in IL-11/Stat3 anti-apoptotic signalling pathway in preconditioning of skeletal myoblasts. | Cardiovascular research 20101001 |
| Diazoxide preconditioning alleviates caspase-dependent and caspase-independent apoptosis induced by anoxia-reoxygenation of PC12 cells. | Journal of biochemistry 20101001 |
| Diazoxide potentiates mesenchymal stem cell survival via NF-kappaB-dependent miR-146a expression by targeting Fas. | American journal of physiology. Heart and circulatory physiology 20101001 |
| Regulation of AMPA receptor currents by mitochondrial ATP-sensitive K+ channels in anoxic turtle neurons. | Journal of neurophysiology 20101001 |
| The effect of 'Teucrium polium L.' extracts on insulin release from in situ isolated perfused rat pancreas in a newly modified isolation method: the role of Ca2+ and K+ channels. | Iranian biomedical journal 20101001 |
| Potassium channel openers exhibit cross-tolerance with morphine in two experimental models of pain. | The West Indian medical journal 20101001 |
| Targeting hypertension with a new adenosine triphosphate-sensitive potassium channel opener iptakalim. | Journal of cardiovascular pharmacology 20100901 |
| Subplasmalemmal Ca(2+) measurements in mouse pancreatic beta cells support the existence of an amplifying effect of glucose on insulin secretion. | Diabetologia 20100901 |
| Autonomic neuropathy predisposes to rosiglitazone-induced vascular leakage in insulin-treated patients with type 2 diabetes: a randomised, controlled trial on thiazolidinedione-induced vascular leakage. | Diabetologia 20100901 |
| Membrane potential-dependent inactivation of voltage-gated ion channels in alpha-cells inhibits glucagon secretion from human islets. | Diabetes 20100901 |
| Hyperinsulinemia precedes insulin resistance in mice lacking pancreatic beta-cell leptin signaling. | Endocrinology 20100901 |
| 17 β-estradiol rapidly increases ATP-sensitive potassium channel activity in gonadotropin-releasing hormone neurons [corrected] via a protein kinase signaling pathway. | Endocrinology 20100901 |
| Advanced diagnostic approaches and current medical management of insulinomas and adrenocortical disease in ferrets (Mustela putorius furo). | The veterinary clinics of North America. Exotic animal practice 20100901 |
| Congenital hyperinsulinism due to mutations in HNF4A and HADH. | Reviews in endocrine & metabolic disorders 20100901 |
| The hyperinsulinism/hyperammonemia syndrome. | Reviews in endocrine & metabolic disorders 20100901 |
| Influence of ATP-dependent K(+)-channel opener on K(+)-cycle and oxygen consumption in rat liver mitochondria. | Biochemistry. Biokhimiia 20100901 |
| Vascular dysfunctions following spinal cord injury. | Journal of medicine and life 20100815 |
| Inhibition or deletion of soluble epoxide hydrolase prevents hyperglycemia, promotes insulin secretion, and reduces islet apoptosis. | The Journal of pharmacology and experimental therapeutics 20100801 |
| Effects of high-density lipoproteins on pancreatic beta-cell insulin secretion. | Arteriosclerosis, thrombosis, and vascular biology 20100801 |
| Autophagy induced by ischemic preconditioning is essential for cardioprotection. | Journal of cardiovascular translational research 20100801 |
| AGI-1067, a novel antioxidant and anti-inflammatory agent, enhances insulin release and protects mouse islets. | Molecular and cellular endocrinology 20100729 |
| Loss of AMP-activated protein kinase alpha2 subunit in mouse beta-cells impairs glucose-stimulated insulin secretion and inhibits their sensitivity to hypoglycaemia. | The Biochemical journal 20100715 |
| Metabolic oscillations in pancreatic islets depend on the intracellular Ca2+ level but not Ca2+ oscillations. | Biophysical journal 20100707 |
| Biotin increases glucokinase expression via soluble guanylate cyclase/protein kinase G, adenosine triphosphate production and autocrine action of insulin in pancreatic rat islets. | The Journal of nutritional biochemistry 20100701 |
| Human K(ATP) channelopathies: diseases of metabolic homeostasis. | Pflugers Archiv : European journal of physiology 20100701 |
| Mitochondria as a source of mechanical signals in cardiomyocytes. | Cardiovascular research 20100701 |
| Transient anoxia and oxyradicals induce a region-specific activation of MAPKs in the embryonic heart. | Molecular and cellular biochemistry 20100701 |
| Gamma-aminobutyric acid (GABA) is an autocrine excitatory transmitter in human pancreatic beta-cells. | Diabetes 20100701 |
| Persistent hyperinsulinemic hypoglycemia of infancy due to homozygous KCNJ11 (T294M) mutation. | Indian journal of pediatrics 20100701 |
| A study of the relationship between pharmacologic preconditioning and adenosine triphosphate-sensitive potassium (KATP) channels on cultured cardiomyocytes using the microelectrode array. | Journal of cardiovascular pharmacology 20100701 |
| [Effect of K-ATP channel opener diazoxide on islet cell apoptosis and the expressions of apoptosis-related genes]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20100701 |
| Anemia and neutropenic fever with high dose diazoxide treatment in a case with hyperinsulinism due to Munchausen by proxy. | Journal of pediatric endocrinology & metabolism : JPEM 20100701 |
| Two unrelated Chinese patients with hyperinsulinism /hyperammonemia (HI/HA) syndrome due to mutations in glutamate dehydrogenase gene. | Journal of pediatric endocrinology & metabolism : JPEM 20100701 |
| Effects of mitochondrial potassium channel and membrane potential on hypoxic human pulmonary artery smooth muscle cells. | American journal of respiratory cell and molecular biology 20100601 |
| Low-level arsenic impairs glucose-stimulated insulin secretion in pancreatic beta cells: involvement of cellular adaptive response to oxidative stress. | Environmental health perspectives 20100601 |
| Octreotide's role in the management of sulfonylurea-induced hypoglycemia. | Journal of medical toxicology : official journal of the American College of Medical Toxicology 20100601 |
| Signaling pathways involved in postconditioning-induced cardioprotection of human myocardium, in vitro. | Experimental biology and medicine (Maywood, N.J.) 20100601 |
| Mechanisms of hydrogen peroxide-induced vasoconstriction in the isolated perfused rat kidney. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100601 |
| The phosphatidylinositol-3 kinase/Akt pathway mediates geranylgeranylacetone-induced neuroprotection against cerebral infarction in rats. | Brain research 20100512 |
| Connexin 43 acts as a cytoprotective mediator of signal transduction by stimulating mitochondrial KATP channels in mouse cardiomyocytes. | The Journal of clinical investigation 20100503 |
| Diazoxide reduces status epilepticus neuron damage in diabetes. | Neurotoxicity research 20100501 |
| Progression of diet-induced diabetes in C57BL6J mice involves functional dissociation of Ca2(+) channels from secretory vesicles. | Diabetes 20100501 |
| Diazoxide-responsive hyperinsulinemic hypoglycemia caused by HNF4A gene mutations. | European journal of endocrinology 20100501 |
| Therapies for the medical management of persistent hypoglycaemia in two cases of inoperable malignant insulinoma. | European journal of endocrinology 20100501 |
| Glucose prevents the fall in ventromedial hypothalamic GABA that is required for full activation of glucose counterregulatory responses during hypoglycemia. | American journal of physiology. Endocrinology and metabolism 20100501 |
| Congenital hyperinsulinism. | Early human development 20100501 |
| Involvement of mitochondrial ATP-sensitive potassium channels in etomidate preconditioning-induced protection in human myeloid HL-60 cells. | Environmental toxicology and pharmacology 20100501 |
| A lethargic neonate and an infant with seizure. | Clinical pediatrics 20100401 |
| Opening of the mitoKATP channel and decoupling of mitochondrial complex II and III contribute to the suppression of myocardial reperfusion hyperoxygenation. | Molecular and cellular biochemistry 20100401 |
| Uncoupling between insulin and release of a D-chiro-inositol-containing inositolphosphoglycan mediator of insulin action in obese women With polycystic ovary syndrome. | Metabolic syndrome and related disorders 20100401 |
| Effects of substitution of Cx43 by Cx32 on myocardial energy metabolism, tolerance to ischaemia and preconditioning protection. | The Journal of physiology 20100401 |
| The intracellular localization and function of the ATP-sensitive K+ channel subunit Kir6.1. | The Journal of membrane biology 20100401 |
| [Influence of diazoxide on mitochondrial apoptosis in human renal tubular cells induced by serum obtained from neonates with asphyxia]. | Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20100401 |
| Inhibition of endogenous hydrogen sulfide synthesis by PAG protects against ethanol-induced gastric damage in the rat. | European journal of pharmacology 20100325 |
| Preconditioning promotes survival and angiomyogenic potential of mesenchymal stem cells in the infarcted heart via NF-kappaB signaling. | Antioxidants & redox signaling 20100315 |
| Six months of diazoxide treatment at bedtime in newly diagnosed subjects with type 1 diabetes does not influence parameters of {beta}-cell function and autoimmunity but improves glycemic control. | Diabetes care 20100301 |
| The KATP channel is a molecular sensor of atrophy in skeletal muscle. | The Journal of physiology 20100301 |
| Polyphenol (-)-epigallocatechin gallate during ischemia limits infarct size via mitochondrial K(ATP) channel activation in isolated rat hearts. | Journal of Korean medical science 20100301 |
| Recurrent hypoglycaemia in a type 2 diabetes patient - diagnostic difficulties. | Archives of medical science : AMS 20100301 |
| [Akt involved in diazoxide preconditioning against rat hippocampal neuronal apoptosis induced by anoxia-reoxygenation injury]. | Zhonghua yi xue za zhi 20100223 |
| K(ATP) channel openers protect mesencephalic neurons against MPP+-induced cytotoxicity via inhibition of ROS production. | Journal of neuroscience research 20100201 |
| Variable effects of the mitoK(ATP) channel modulators diazoxide and 5-HD in ATP-depleted renal epithelial cells. | Molecular and cellular biochemistry 20100201 |
| Coupling of liquid chromatography/tandem mass spectrometry and liquid chromatography/solid-phase extraction/NMR techniques for the structural identification of metabolites following in vitro biotransformation of SUR1-selective ATP-sensitive potassium channel openers. | Drug metabolism and disposition: the biological fate of chemicals 20100201 |
| Inhibition of oxygen consumption in skeletal muscle-derived mitochondria by pinacidil, diazoxide, and glibenclamide, but not by 5-hydroxydecanoate. | Journal of bioenergetics and biomembranes 20100201 |
| Sevoflurane pre- and post-conditioning protect the brain via the mitochondrial K ATP channel. | British journal of anaesthesia 20100201 |
| Pharmacological stimulation and inhibition of insulin secretion in mouse islets lacking ATP-sensitive K+ channels. | British journal of pharmacology 20100201 |
| Transplantation of mesenchymal stem cells preconditioned with diazoxide, a mitochondrial ATP-sensitive potassium channel opener, promotes repair of myocardial infarction in rats. | The Tohoku journal of experimental medicine 20100201 |
| [Effects of diazoxide on the mitochondrial ultrastructure and permeability in donor rat myocardium]. | Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20100201 |
| Ischemic postconditioning may not influence early brain injury induced by focal cerebral ischemia/reperfusion in rats. | Korean journal of anesthesiology 20100201 |
| Improved insulin sensitivity and islet function after PPARdelta activation in diabetic db/db mice. | European journal of pharmacology 20100125 |
| [Effect of diazoxide on oxygen free radicals and cell apoptosis in brain tissue after deep hypothermia cerebral ischemia reperfusion injury in young rats]. | Zhonghua wai ke za zhi [Chinese journal of surgery] 20100115 |
| Chloro-substituted 3-alkylamino-4H-1,2,4-benzothiadiazine 1,1-dioxides as ATP-sensitive potassium channel activators: impact of the position of the chlorine atom on the aromatic ring on activity and tissue selectivity. | Journal of medicinal chemistry 20100114 |
| Preconditioning with diazoxide prevents reoxygenation-induced rigor-type hypercontracture. | Journal of molecular and cellular cardiology 20100101 |
| Anti-ischemic properties of a new spiro-cyclic benzopyran activator of the cardiac mito-KATP channel. | Biochemical pharmacology 20100101 |
| Terminalia bellirica stimulates the secretion and action of insulin and inhibits starch digestion and protein glycation in vitro. | The British journal of nutrition 20100101 |
| Differential K(ATP) channel pharmacology in intact mouse heart. | Journal of molecular and cellular cardiology 20100101 |
| ATP-sensitive K+ channel mediates the zinc switch-off signal for glucagon response during glucose deprivation. | Diabetes 20100101 |
| Increased potassium conductance of brain mitochondria induces resistance to permeability transition by enhancing matrix volume. | The Journal of biological chemistry 20100101 |
| Modeling mitochondrial bioenergetics with integrated volume dynamics. | PLoS computational biology 20100101 |
| Direct effects of K(ATP) channel openers pinacidil and diazoxide on oxidative phosphorylation of mitochondria in situ. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101 |
| Defective secretion of islet hormones in chromogranin-B deficient mice. | PloS one 20100101 |
| Congenital hyperinsulinism due to a compound heterozygous ABCC8 mutation with spontaneous resolution at eight weeks. | Hormone research in paediatrics 20100101 |
| Novel neuroprotective strategies in ischemic retinal lesions. | International journal of molecular sciences 20100101 |
| Insulinoma in a patient with MEN 1 syndrome--9-year follow-up: case report. | Endokrynologia Polska 20100101 |
| Potent cardioprotective effect of the 4-anilinoquinazoline derivative PD153035: involvement of mitochondrial K(ATP) channel activation. | PloS one 20100101 |
| Diazoxide promotes oligodendrocyte precursor cell proliferation and myelination. | PloS one 20100101 |
| Hypoglycaemia following upper gastrointestinal surgery: case report and review of the literature. | BMC gastroenterology 20100101 |
| Nonclassic congenital adrenal hyperplasia. | International journal of pediatric endocrinology 20100101 |
| Dual role of nNOS in ischemic injury and preconditioning. | BMC physiology 20100101 |
| Mitochondrial preconditioning: a potential neuroprotective strategy. | Frontiers in aging neuroscience 20100101 |
| The KATP channel activator diazoxide ameliorates amyloid-β and tau pathologies and improves memory in the 3xTgAD mouse model of Alzheimer's disease. | Journal of Alzheimer's disease : JAD 20100101 |
| Electrical short-circuit in β-cells from a patient with non-insulinoma pancreatogenous hypoglycemic syndrome (NIPHS): a case report. | Journal of medical case reports 20100101 |
| Neuroprotective properties of levosimendan in an in vitro model of traumatic brain injury. | BMC neurology 20100101 |
| Hyperinsulinemic hypoglycemias in infancy and childhood--diagnostic therapeutic algorithm with contribution of two cases. | Folia medica 20100101 |
| Expression and regulation of cyclic nucleotide phosphodiesterases in human and rat pancreatic islets. | PloS one 20100101 |
| Endocrinology of hirsutism. | International journal of trichology 20100101 |
| [Effect of mitochondrial ATP-dependent potassium channel effectors diazoxide and glybenclamide on hydrodynamic diameter and membrane potential of the myometrial mitochondria]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20100101 |
| Magnesium Lithospermate B Protects Cardiomyocytes from Ischemic Injury Via Inhibition of TAB1-p38 Apoptosis Signaling. | Frontiers in pharmacology 20100101 |
| Adverse drug effects in hospitalized elderly: data from the healthcare cost and utilization project. | Clinical pharmacology : advances and applications 20100101 |
| Congenital hyperinsulinism with hyperammonaemia. | BMJ case reports 20100101 |
| Diazoxide protects against hydrogen peroxide-induced toxicity in the osteoblastic MC3T3-E1 cells. | European journal of pharmacology 20091210 |
| Chronic palmitate exposure inhibits insulin secretion by dissociation of Ca(2+) channels from secretory granules. | Cell metabolism 20091202 |
| Congenital disorder of glycosylation type Ia: heterogeneity in the clinical presentation from multivisceral failure to hyperinsulinaemic hypoglycaemia as leading symptoms in three infants with phosphomannomutase deficiency. | Journal of inherited metabolic disease 20091201 |
| Diazoxide reverses the enhanced expression of KATP subunits in cholinergic neurons caused by exposure to Aβ₁₋₄₂. | Neurochemical research 20091201 |
| Glucose deprivation regulates KATP channel trafficking via AMP-activated protein kinase in pancreatic beta-cells. | Diabetes 20091201 |
| Galanin potentiates supramaximal caerulein-stimulated pancreatic amylase secretion via its action on somatostatin secretion. | American journal of physiology. Gastrointestinal and liver physiology 20091201 |
| Mitochondrial KATP opening confers protection against lethal myocardial injury and ischaemia-induced arrhythmias in the rat heart via PI3K/Akt-dependent and -independent mechanisms. | Canadian journal of physiology and pharmacology 20091201 |
| Bistability of mitochondrial respiration underlies paradoxical reactive oxygen species generation induced by anoxia. | PLoS computational biology 20091201 |
| Distinct effects of CGRP on typical and atypical smooth muscle cells involved in generating spontaneous contractions in the mouse renal pelvis. | British journal of pharmacology 20091201 |
| Molecular identification and functional characterization of a mitochondrial sulfonylurea receptor 2 splice variant generated by intraexonic splicing. | Circulation research 20091120 |
| New R/S-3,4-dihydro-2,2-dimethyl-2H-1-benzopyrans as K(ATP) channel openers: modulation of the 4-position. | Bioorganic & medicinal chemistry 20091115 |
| Early preconditioning protection against stunning in conscious sheep. Role of KATP channels. | Molecular and cellular biochemistry 20091101 |
| Mitogen-activated protein kinase p38alpha and retinal ischemic preconditioning. | Experimental eye research 20091101 |
| Hyperinsulinism-hyperammonaemia syndrome: novel mutations in the GLUD1 gene and genotype-phenotype correlations. | European journal of endocrinology 20091101 |
| Synthesis of modified 4H-1,2,4-benzothiadiazine-1,1-dioxides and determination of their affinity and selectivity for different types of K(ATP) channels. | ChemMedChem 20091101 |
| Beneficial effects of K-ATP channel openers in diabetes: an update on mechanisms and clinical experiences. | Diabetes, obesity & metabolism 20091101 |
| The role of KATP channels on propofol preconditioning in a cellular model of renal ischemia-reperfusion. | Anesthesia and analgesia 20091101 |
| Quantitative measurement of zinc secretion from pancreatic islets with high temporal resolution using droplet-based microfluidics. | Analytical chemistry 20091101 |
| Immunotherapy for the prevention and treatment of type 1 diabetes: human trials and a look into the future. | Diabetes care 20091001 |
| [Persistent hyperinsulinemic hypoglycemia of infancy: clinical analysis of 12 cases]. | Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20091001 |
| Phosphorylation of connexin-43 at serine 262 promotes a cardiac injury-resistant state. | Cardiovascular research 20090901 |
| Angiotensin II and tumour necrosis factor alpha as mediators of ATP-dependent potassium channel remodelling in post-infarction heart failure. | Cardiovascular research 20090901 |
| Successful medical management of status post-Roux-en-Y-gastric-bypass hyperinsulinemic hypoglycemia. | Obesity surgery 20090901 |
| Successful control of intractable hypoglycemia using rapamycin in an 86-year-old man with a pancreatic insulin-secreting islet cell tumor and metastases. | The Journal of clinical endocrinology and metabolism 20090901 |
| Radiofrequency ablation of solitary pancreatic insulinoma in a patient with episodes of severe hypoglycemia. | European journal of gastroenterology & hepatology 20090901 |
| ATP-sensitive potassium currents in rat primary afferent neurons: biophysical, pharmacological properties, and alterations by painful nerve injury. | Neuroscience 20090818 |
| Lysosomal and proteasome-dependent proteolysis are differentially regulated by insulin and/or amino acids following feeding in young, mature and old rats. | The Journal of nutritional biochemistry 20090801 |
| Deletion of PKCepsilon selectively enhances the amplifying pathways of glucose-stimulated insulin secretion via increased lipolysis in mouse beta-cells. | Diabetes 20090801 |
| Glucagon-like peptide-1 protects beta-cells against apoptosis by increasing the activity of an IGF-2/IGF-1 receptor autocrine loop. | Diabetes 20090801 |
| Somatostatin release, electrical activity, membrane currents and exocytosis in human pancreatic delta cells. | Diabetologia 20090801 |
| Isoflurane induces a postconditioning effect on bovine pulmonary arterial endothelial cells exposed to oxygen-glucose deprivation. | European journal of pharmacology 20090801 |
| Plasma membrane depolarization as a determinant of the first phase of insulin secretion. | American journal of physiology. Endocrinology and metabolism 20090801 |
| Galanin inhibits caerulein-stimulated pancreatic amylase secretion via cholinergic nerves and insulin. | American journal of physiology. Gastrointestinal and liver physiology 20090801 |
| Glucose sensing during hypoglycemia: lessons from the lab. | Diabetes care 20090801 |
| Hypoglycemia: from the laboratory to the clinic. | Diabetes care 20090801 |
| [Diabetes counteracts the protective effect of the diazoxide preconditioning on ischemic reperfused rat heart]. | Zhonghua wai ke za zhi [Chinese journal of surgery] 20090801 |
| Role of mitochondrial ATP-sensitive potassium channels on fatigue in mouse muscle fibers. | Biochemical and biophysical research communications 20090717 |
| Evidence for an ATP-sensitive K+ channel in mitoplasts isolated from Trypanosoma cruzi and Crithidia fasciculata. | International journal for parasitology 20090715 |
| Inhibitory effects of leptin on pancreatic alpha-cell function. | Diabetes 20090701 |
| 3-Hydroxyacyl-coenzyme A dehydrogenase deficiency and hyperinsulinemic hypoglycemia: characterization of a novel mutation and severe dietary protein sensitivity. | The Journal of clinical endocrinology and metabolism 20090701 |
| Sesquiterpenoids from antidiabetic Psacalium decompositum block ATP sensitive potassium channels. | Journal of ethnopharmacology 20090625 |
| Hyperinsulinaemic hypoglycaemia. | Archives of disease in childhood 20090601 |
| The phenomenon of seasonal pseudohypokalemia: effects of ambient temperature, plasma glucose and role for sodium-potassium-exchanging-ATPase. | Clinical biochemistry 20090601 |
| Extremes of clinical and enzymatic phenotypes in children with hyperinsulinism caused by glucokinase activating mutations. | Diabetes 20090601 |
| Ambivalent effects of diazoxide on mitochondrial ROS production at respiratory chain complexes I and III. | Biochimica et biophysica acta 20090601 |
| Role of the nitric oxide on diazoxide-induced relaxation of the calf cardiac vein and coronary artery during cooling. | Fundamental & clinical pharmacology 20090601 |
| Intermittent adenosine at the beginning of reperfusion does not trigger cardioprotection. | The Journal of surgical research 20090515 |
| ATP-sensitive potassium channels control glioma cells proliferation by regulating ERK activity. | Carcinogenesis 20090501 |
| Oleic acid directly regulates POMC neuron excitability in the hypothalamus. | Journal of neurophysiology 20090501 |
| Possible role of JAK-2 in attenuated cardioprotective effect of ischemic preconditioning in hyperhomocysteinemic rat hearts. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20090501 |
| Cardiac dysfunctions following spinal cord injury. | Journal of medicine and life 20090415 |
| Leptin-dependent phosphorylation of PTEN mediates actin restructuring and activation of ATP-sensitive K+ channels. | The Journal of biological chemistry 20090403 |
| Iptakalim protects against MPP+-induced degeneration of dopaminergic neurons in association with astrocyte activation. | The international journal of neuropsychopharmacology 20090401 |
| Iptakalim ameliorates MPP+-induced astrocyte mitochondrial dysfunction by increasing mitochondrial complex activity besides opening mitoK(ATP) channels. | Journal of neuroscience research 20090401 |
| Glucose-dependent and -independent electrical activity in islets of Langerhans of Psammomys obesus, an animal model of nutritionally induced obesity and diabetes. | General and comparative endocrinology 20090401 |
| Insulin counteracts glucotoxic effects by suppressing thioredoxin-interacting protein production in INS-1E beta cells and in Psammomys obesus pancreatic islets. | Diabetologia 20090401 |
| Endothelial heparanase secretion after acute hypoinsulinemia is regulated by glucose and fatty acid. | American journal of physiology. Heart and circulatory physiology 20090401 |
| Identification of a chemical probe for NAADP by virtual screening. | Nature chemical biology 20090401 |
| Diazoxide protects myocardial mitochondria, metabolism, and function during cardiac surgery: a double-blind randomized feasibility study of diazoxide-supplemented cardioplegia. | The Journal of thoracic and cardiovascular surgery 20090401 |
| The insulinotropic effect of fluoroquinolones. | Biochemical pharmacology 20090315 |
| Involvement of hippocampal CA3 K(ATP) channels in contextual memory. | Neuropharmacology 20090301 |
| Gene silencing of phogrin unveils its essential role in glucose-responsive pancreatic beta-cell growth. | Diabetes 20090301 |
| The role of Akt/protein kinase B subtypes in retinal ischemic preconditioning. | Experimental eye research 20090301 |
| Nicorandil attenuates FeCl(3)-induced thrombus formation through the inhibition of reactive oxygen species production. | Circulation journal : official journal of the Japanese Circulation Society 20090301 |
| A new mechanism and strategy for inhibiting thrombus formation in the artery. | Circulation journal : official journal of the Japanese Circulation Society 20090301 |
| [Regulation of rat airway smooth muscle cell proliferation by mitochondrial ATP-sensitive K(+) channel in asthmic rats.]. | Sheng li xue bao : [Acta physiologica Sinica] 20090225 |
| Impaired mitochondria-dependent vasodilation in cerebral arteries of Zucker obese rats with insulin resistance. | American journal of physiology. Regulatory, integrative and comparative physiology 20090201 |
| Glucose and pharmacological modulators of ATP-sensitive K+ channels control [Ca2+]c by different mechanisms in isolated mouse alpha-cells. | Diabetes 20090201 |
| Intergenerational transmission of glucose intolerance and obesity by in utero undernutrition in mice. | Diabetes 20090201 |
| Nutrient-dependent secretion of glucose-dependent insulinotropic polypeptide from primary murine K cells. | Diabetologia 20090201 |
| The alpha-cell conundrum: ATP-sensitive K+ channels and glucose sensing. | Diabetes 20090201 |
| Effects of ATP-sensitive potassium channels on the expression of P21, P27 and leptin. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20090201 |
| Blockade of the erbB2 receptor induces cardiomyocyte death through mitochondrial and reactive oxygen species-dependent pathways. | The Journal of biological chemistry 20090123 |
| Effect of obestatin on insulin, glucagon and somatostatin secretion in the perfused rat pancreas. | Regulatory peptides 20090108 |
| Protection against ischemia-induced ventricular arrhythmias and myocardial dysfunction conferred by preconditioning in the rat heart: involvement of mitochondrial K(ATP) channels and reactive oxygen species. | Physiological research 20090101 |
| Glucose controls cytosolic Ca2+ and insulin secretion in mouse islets lacking adenosine triphosphate-sensitive K+ channels owing to a knockout of the pore-forming subunit Kir6.2. | Endocrinology 20090101 |
| Regulation of calcium-permeable TRPV2 channel by insulin in pancreatic beta-cells. | Diabetes 20090101 |
| Diazoxide-mediated growth inhibition in human lung cancer cells via downregulation of beta-catenin-mediated cyclin D1 transcription. | Lung 20090101 |
| Identification of antihypertensive drugs which inhibit amyloid-beta protein oligomerization. | Journal of Alzheimer's disease : JAD 20090101 |
| Laparoscopic pancreatectomy for persistent hyperinsulinemic hypoglycemia of infancy. | Journal of pediatric surgery 20090101 |
| Pancreatic insulinoma co-existing with gastric GIST in the absence of neurofibromatosis-1. | World journal of surgical oncology 20090101 |
| Connexins: a myriad of functions extending beyond assembly of gap junction channels. | Cell communication and signaling : CCS 20090101 |
| Nitric oxide activates ATP-sensitive potassium channels in mammalian sensory neurons: action by direct S-nitrosylation. | Molecular pain 20090101 |
| Childhood craniopharyngioma: greater hypothalamic involvement before surgery is associated with higher homeostasis model insulin resistance index. | BMC pediatrics 20090101 |
| Sweet taste receptor expressed in pancreatic beta-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion. | PloS one 20090101 |
| The mitochondrial ATP-sensitive potassium channel blocker 5-hydroxydecanoate inhibits toxicity of 6-hydroxydopamine on dopaminergic neurons. | Neurotoxicity research 20090101 |
| Reducing stillbirths: prevention and management of medical disorders and infections during pregnancy. | BMC pregnancy and childbirth 20090101 |
| [Effect of adenosine triphosphate-dependent potassium channel activators on electrical reactions of intact and cultured endothelial cells]. | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20090101 |
| The role of ATP-sensitive potassium channel blockers in ischemia-reperfusion-induced renal injury versus their effects on cardiac ischemia reperfusion in rats. | European review for medical and pharmacological sciences 20090101 |
| Impact of modulators of mitochondrial ATP-sensitive potassium channel (mitoK(ATP)) on hypoxic pulmonary vasoconstriction. | Advances in experimental medicine and biology 20090101 |
| Acute ablation of PERK results in ER dysfunctions followed by reduced insulin secretion and cell proliferation. | BMC cell biology 20090101 |
| Beneficial effect of the oxygen free radical scavenger amifostine (WR-2721) on spinal cord ischemia/reperfusion injury in rabbits. | Journal of cardiothoracic surgery 20090101 |
| [Diagnostics and treatment of organic hyperinsulinism--experience in 105 cases]. | Casopis lekaru ceskych 20090101 |
| Neuroprotective effects of diazoxide and its antagonism by glibenclamide in pyramidal neurons of rat hippocampus subjected to ischemia-reperfusion-induced injury. | The International journal of neuroscience 20090101 |
| Acute dystonic reactions in a lady presenting with repetitive involuntary muscle twitching: a case report. | Cases journal 20090101 |
| Glucose metabolism, islet architecture, and genetic homogeneity in imprinting of [Ca2+](i) and insulin rhythms in mouse islets. | PloS one 20090101 |
| Role of potassium channels in stretch-promoted atrial natriuretic factor secretion. | Journal of the American Society of Hypertension : JASH 20090101 |
| Possible role of an ischemic preconditioning-like response mechanism in K(ATP) channel opener-mediated protection against streptozotocin-induced suppression of rat pancreatic islet function. | Biochemical pharmacology 20081215 |
| Differential structure of atrial and ventricular KATP: atrial KATP channels require SUR1. | Circulation research 20081205 |
| Weight loss in obese men by caloric restriction and high-dose diazoxide-mediated insulin suppression. | Diabetes, obesity & metabolism 20081201 |
| Syntaxin-1A inhibition of P-1075, cromakalim, and diazoxide actions on mouse cardiac ATP-sensitive potassium channel. | Cardiovascular research 20081201 |
| Amplified hormonal counterregulatory responses to hypoglycemia in rats after systemic delivery of a SUR-1-selective K(+) channel opener? | Diabetes 20081201 |
| Na+/H+ exchanger-1 inhibitors decrease myocardial superoxide production via direct mitochondrial action. | Journal of applied physiology (Bethesda, Md. : 1985) 20081201 |
| A peptide of the phylloseptin family from the skin of the frog Hylomantis lemur (Phyllomedusinae) with potent in vitro and in vivo insulin-releasing activity. | Peptides 20081201 |
| Synthesis and pharmacological evaluation of a second generation of pyridothiadiazine 1,1-dioxides acting as AMPA potentiators. | Bioorganic & medicinal chemistry 20081201 |
| Minimizing hypoglycemia while maintaining glycemic control in diabetes. | Diabetes 20081201 |
| American College of Endocrinology Pre-Diabetes Consensus Conference: part three. | Diabetes care 20081201 |
| Long lasting synchronization of calcium oscillations by cholinergic stimulation in isolated pancreatic islets. | Biophysical journal 20081115 |
| Preconditioning by an in situ administration of hydrogen peroxide: involvement of reactive oxygen species and mitochondrial ATP-dependent potassium channel in a cerebral ischemia-reperfusion model. | Brain research 20081113 |
| Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. | Journal of medicinal chemistry 20081113 |
| Spirocyclic benzopyran-based derivatives as new anti-ischemic activators of mitochondrial ATP-sensitive potassium channel. | Journal of medicinal chemistry 20081113 |
| The L-Type Ca+ and KATP channels may contribute to pacing-induced protection against anoxia-reoxygenation in the embryonic heart model. | Journal of cardiovascular electrophysiology 20081101 |
| Coassembly of different sulfonylurea receptor subtypes extends the phenotypic diversity of ATP-sensitive potassium (KATP) channels. | Molecular pharmacology 20081101 |
| Chronic sustained and intermittent hypoxia reduce function of ATP-sensitive potassium channels in nucleus of the solitary tract. | American journal of physiology. Regulatory, integrative and comparative physiology 20081101 |
| Diazoxide enhances basal metabolic rate and fat oxidation in obese Zucker rats. | Metabolism: clinical and experimental 20081101 |
| Involvement of mitoKATP channel in protective mechanisms of cerebral ischemic tolerance. | Brain research 20081031 |
| Diazoxide-induced beta-cell rest reduces endoplasmic reticulum stress in lipotoxic beta-cells. | The Journal of endocrinology 20081001 |
| Protein kinase C subtypes and retinal ischemic preconditioning. | Experimental eye research 20081001 |
| Mary, Mary, quite contrary, how do your beta-cells fail? | Diabetes 20081001 |
| Chronic antidiabetic sulfonylureas in vivo: reversible effects on mouse pancreatic beta-cells. | PLoS medicine 20081001 |
| Why treatment fails in type 2 diabetes. | PLoS medicine 20081001 |
| Calcium uptake in rat liver mitochondria accompanied by activation of ATP-dependent potassium channel. | Biochemistry. Biokhimiia 20081001 |
| Use of a continuous glucose monitor in the management of inoperable metastatic insulinoma: a case report. | Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20081001 |
| Hydrogen sulfide augments neutrophil migration through enhancement of adhesion molecule expression and prevention of CXCR2 internalization: role of ATP-sensitive potassium channels. | Journal of immunology (Baltimore, Md. : 1950) 20080915 |
| Diazoxide increases liver and kidney HSP25 and HSP70 after shock and stroke. | The Journal of surgical research 20080901 |
| Influence of sedentary versus physically active conditions on regulation of plasma renin activity and vasopressin. | American journal of physiology. Regulatory, integrative and comparative physiology 20080901 |
| Sulfonylurea receptor-dependent and -independent pathways mediate vasodilation induced by ATP-sensitive K+ channel openers. | Molecular pharmacology 20080901 |
| Stimulation of contractions in human myometrium by serotonin is unmasked by smooth muscle relaxants. | Reproductive sciences (Thousand Oaks, Calif.) 20080901 |
| Long-term exposure of mouse pancreatic islets to oleate or palmitate results in reduced glucose-induced somatostatin and oversecretion of glucagon. | Diabetologia 20080901 |
| Bringing light to the dark side of insulin: a journey across the blood-brain barrier. | Diabetes 20080901 |
| Opening of microglial K(ATP) channels inhibits rotenone-induced neuroinflammation. | Journal of cellular and molecular medicine 20080901 |
| [Hyperinsulinemic hypoglycemia in adults. Case reports and a short review]. | Orvosi hetilap 20080831 |
| The mechanisms of propofol-induced block on ion currents in differentiated H9c2 cardiac cells. | European journal of pharmacology 20080820 |
| Brief femoral artery ischaemia provides protection against myocardial ischaemia-reperfusion injury in rats: the possible mechanisms. | Experimental physiology 20080801 |
| Protein kinase C-delta mediates neuronal apoptosis in the retinas of diabetic rats via the Akt signaling pathway. | Diabetes 20080801 |
| Mouth breathing increases the pentylenetetrazole-induced seizure threshold in mice: a role for ATP-sensitive potassium channels. | Epilepsy & behavior : E&B 20080801 |
| Protein kinase D is a key regulator of cardiomyocyte lipoprotein lipase secretion after diabetes. | Circulation research 20080801 |
| Intramitochondrial signaling: interactions among mitoKATP, PKCepsilon, ROS, and MPT. | American journal of physiology. Heart and circulatory physiology 20080801 |
| Clinical characteristics and biochemical mechanisms of congenital hyperinsulinism associated with dominant KATP channel mutations. | The Journal of clinical investigation 20080801 |
| Glucose and glucose transporters regulate lymphatic pump activity through activation of the mitochondrial ATP-sensitive K+ channel. | The journal of physiological sciences : JPS 20080801 |
| [Bax is involved in K ATP-mediated protection of the hippocampal neurons against hypoxic exposure]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080801 |
| Non-islet-cell tumor hypoglycemia and lactic acidosis in a child with congenital HIV and Burkitt's lymphoma. | Journal of pediatric endocrinology & metabolism : JPEM 20080801 |
| Pharmacological prevention of peri-, and post-procedural myocardial injury in percutaneous coronary intervention. | Current cardiology reviews 20080801 |
| Novel de novo mutation in sulfonylurea receptor 1 presenting as hyperinsulinism in infancy followed by overt diabetes in early adolescence. | Diabetes 20080701 |
| Bax, Bak and mitochondrial oxidants are involved in hypoxia-reoxygenation-induced apoptosis in human placenta. | Placenta 20080701 |
| Insulinoma in a third-trimester pregnant woman combined with pre-eclampsia: a case report and review of the diagnostic strategies. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20080701 |
| Continuous glucose monitoring in patients with insulinoma. | Clinical endocrinology 20080601 |
| Dual effect of nitric oxide on ATP-sensitive K+ channels in rat pancreatic beta cells. | Pflugers Archiv : European journal of physiology 20080601 |
| Persistent hyperinsulinemic hypoglycemia and maturity-onset diabetes of the young due to heterozygous HNF4A mutations. | Diabetes 20080601 |
| Gene duplications resulting in over expression of glucokinase are not a common cause of hypoglycaemia of infancy in humans. | Molecular genetics and metabolism 20080601 |
| Modulation of the c-Jun N-terminal kinase activity in the embryonic heart in response to anoxia-reoxygenation: involvement of the Ca2+ and mitoKATP channels. | Molecular and cellular biochemistry 20080601 |
| Effects of the selective EET antagonist, 14,15-EEZE, on cardioprotection produced by exogenous or endogenous EETs in the canine heart. | American journal of physiology. Heart and circulatory physiology 20080601 |
| Synthesis and activity on rat aorta rings and rat pancreatic beta-cells of ring-opened analogues of benzopyran-type potassium channel activators. | Bioorganic & medicinal chemistry 20080601 |
| Is octreotide a risk factor in necrotizing enterocolitis? | Journal of pediatric surgery 20080601 |
| Water and ion channels: crucial in the initiation and progression of apoptosis in central nervous system? | Current neuropharmacology 20080601 |
| Neuroprotective effect of diazoxide on brain injury induced by cerebral ischemia/reperfusion during deep hypothermia. | Journal of the neurological sciences 20080515 |
| Redox properties of the adenoside triphosphate-sensitive K+ channel in brain mitochondria. | Journal of neuroscience research 20080515 |
| New R/S-3,4-dihydro-2,2-dimethyl-6-halo-4-(phenylaminothiocarbonylamino)-2H-1-benzopyrans structurally related to (+/-)-cromakalim as tissue-selective pancreatic beta-cell K(ATP) channel openers. | Bioorganic & medicinal chemistry 20080515 |
| KATP channel openers facilitate glutamate uptake by GluTs in rat primary cultured astrocytes. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080501 |
| Quebrachitol-induced gastroprotection against acute gastric lesions: role of prostaglandins, nitric oxide and K+ ATP channels. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20080501 |
| Induction of carbonic anhydrase IX by hypoxia and chemical disruption of oxygen sensing in rat fibroblasts and cardiomyocytes. | Pflugers Archiv : European journal of physiology 20080501 |
| Non-insulinoma persistent hyperinsulinaemic hypoglycaemia caused by an activating glucokinase mutation: hypoglycaemia unawareness and attacks. | Clinical endocrinology 20080501 |
| Ovarian steroids stimulate adenosine triphosphate-sensitive potassium (KATP) channel subunit gene expression and confer responsiveness of the gonadotropin-releasing hormone pulse generator to KATP channel modulation. | Endocrinology 20080501 |
| Effect of diazoxide on flavoprotein oxidation and reactive oxygen species generation during ischemia-reperfusion: a study on Langendorff-perfused rat hearts using optic fibers. | American journal of physiology. Heart and circulatory physiology 20080501 |
| A Kir6.2 mutation causing severe functional effects in vitro produces neonatal diabetes without the expected neurological complications. | Diabetologia 20080501 |
| KATP channel openers have opposite effects on mitochondrial respiration under different energetic conditions. | Journal of cardiovascular pharmacology 20080501 |
| Effect of pressure overload on cardioprotection of mitochondrial KATP channels and GSK-3beta: interaction with the MPT pore. | American journal of hypertension 20080501 |
| [18F-fluoro-L-DOPA PET-CT imaging combined with genetic analysis for optimal classification and treatment in a child with severe congenital hyperinsulinism]. | Anales de pediatria (Barcelona, Spain : 2003) 20080501 |
| Life-threatening hyperkalemia following partial pancreatectomy for neonatal hyperinsulinism. | Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20080501 |
| Pulmonary hypertension, heart failure and neutropenia due to diazoxide therapy. | Advances in therapy 20080501 |
| All-trans retinoic acid prevents angiotensin II- and mechanical stretch-induced reactive oxygen species generation and cardiomyocyte apoptosis. | Journal of cellular physiology 20080401 |
| The paradigm of postconditioning to protect the heart. | Journal of cellular and molecular medicine 20080401 |
| Involvement of amlodipine, diazoxide, and glibenclamide in development of morphine tolerance in mice. | The International journal of neuroscience 20080401 |
| Correlates between hyperinsulinism and hyperandrogenemia? | Fertility and sterility 20080401 |
| Differential increase of mitochondrial matrix volume by sevoflurane in isolated cardiac mitochondria. | Anesthesia and analgesia 20080401 |
| 20(S)-ginsenoside Rg3 enhances glucose-stimulated insulin secretion and activates AMPK. | Biological & pharmaceutical bulletin 20080401 |
| Amelioration of oxidative mitochondrial DNA damage and deletion after renal ischemic injury by the KATP channel opener diazoxide. | American journal of physiology. Renal physiology 20080301 |
| [Protective effect of ischemia and diazoxide preconditioning on postischemic reperfused myocardium and possible mechanism thereof]. | Zhonghua yi xue za zhi 20080226 |
| [Effects of diazoxide on Fas/FasL protein expressions in rat myocardium suffered from long-term hypothermic preservation]. | Sheng li xue bao : [Acta physiologica Sinica] 20080225 |
| Mitochondrial ATP-sensitive K+ channels regulate NMDAR activity in the cortex of the anoxic western painted turtle. | The Journal of physiology 20080215 |
| Delayed pharmacological pre-conditioning effect of mitochondrial ATP-sensitive potassium channel opener on neurologic injury in a rabbit model of spinal cord ischemia. | Acta anaesthesiologica Scandinavica 20080201 |
| Role of the NO/cGMP/K(ATP) pathway in the protective effects of sildenafil against ethanol-induced gastric damage in rats. | British journal of pharmacology 20080201 |
| Insulin-releasing properties of the frog skin peptide pseudin-2 and its [Lys18]-substituted analogue. | Biological chemistry 20080201 |
| Enhanced activation of phospholipase C and insulin secretion from islets incubated in fatty acid-free bovine serum albumin. | Metabolism: clinical and experimental 20080201 |
| Sildenafil inhibits duodenal contractility via activation of the NO-K+ channel pathway. | Fundamental & clinical pharmacology 20080201 |
| The spontaneous mechanical activity of the circular smooth muscle of the rabbit colon in vitro. | Pharmacological research 20080201 |
| Association of malignant insulinoma and type 2 diabetes mellitus: a case report. | Annales d'endocrinologie 20080201 |
| KATP channel openers: tissue selectivity of original 3-alkylaminopyrido- and 3-alkylaminobenzothiadiazine 1,1-dioxides. | Biochemical pharmacology 20080115 |
| Glucose induces synchronous mitochondrial calcium oscillations in intact pancreatic islets. | Cell calcium 20080101 |
| Reduced expression of Kir6.2/SUR2A subunits explains KATP deficiency in K+-depleted rats. | Neuromuscular disorders : NMD 20080101 |
| Acute diabetes moderates trafficking of cardiac lipoprotein lipase through p38 mitogen-activated protein kinase-dependent actin cytoskeleton organization. | Diabetes 20080101 |
| Importance of timing of magnesium administration in the isolated ischemic-reperfused rat heart: role of K(ATP) channels. | Physiological research 20080101 |
| Diazoxide prevents abdominal adiposity and fatty liver in obese OLETF rats at prediabetic stage. | Journal of diabetes and its complications 20080101 |
| [Physiological properties and possible correction of adenosine triphosphate-sensitive potassium channel function]. | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20080101 |
| Palmitate-induced beta-cell dysfunction is associated with excessive NO production and is reversed by thiazolidinedione-mediated inhibition of GPR40 transduction mechanisms. | PloS one 20080101 |
| Long-term non-surgical therapy of severe persistent congenital hyperinsulinism with glucagon. | Hormone research 20080101 |
| Pituitary hypoplasia and growth hormone deficiency in a woman with glycogen storage disease type Ia: a case report. | Journal of medical case reports 20080101 |
| A pharmacological analysis of the possible role of vasoactive mediators in compensatory coronary blood flow. | Experimental and clinical cardiology 20080101 |
| Membrane potential controls adipogenic and osteogenic differentiation of mesenchymal stem cells. | PloS one 20080101 |
| Preoperative detection of insulinomas: two case reports. | Cases journal 20080101 |
| Mutations in UCP2 in congenital hyperinsulinism reveal a role for regulation of insulin secretion. | PloS one 20080101 |
| [Diazoxide-induced mitochondrial swelling in the rat myometrium as a consequence of the activation of the mitochondrial ATP-sensitive (K+)-channel]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20080101 |
| Amyloid deposition in transplanted human pancreatic islets: a conceivable cause of their long-term failure. | Experimental diabetes research 20080101 |
| Episodic confusional state: Due to insulinoma. | Indian journal of psychiatry 20080101 |
| Hirsutism: clinico-investigative profile of 50 Indian patients. | Indian journal of dermatology 20080101 |
| Is beta-cell failure in type 2 diabetes mellitus reversible? | International journal of diabetes in developing countries 20080101 |
| Compound K enhances insulin secretion with beneficial metabolic effects in db/db mice. | Journal of agricultural and food chemistry 20071226 |
| epsilonPKC phosphorylates the mitochondrial K(+) (ATP) channel during induction of ischemic preconditioning in the rat hippocampus. | Brain research 20071212 |
| Voltage-gated Ca(2+) influx and insulin secretion in human and mouse beta-cells are impaired by the mitochondrial Na(+)/Ca(2+) exchange inhibitor CGP-37157. | European journal of pharmacology 20071208 |
| Connexin 43 in ischemic pre- and postconditioning. | Heart failure reviews 20071201 |
| Nutrient control of insulin secretion in perifused adult pig islets. | Diabetes & metabolism 20071201 |
| Heterogeneity in disease severity in a family with a novel G68V GCK activating mutation causing persistent hyperinsulinaemic hypoglycaemia of infancy. | Diabetic medicine : a journal of the British Diabetic Association 20071201 |
| Modulation of acute visceral nociception and bladder inflammation by plant triterpene, alpha, beta-amyrin in a mouse model of cystitis: role of tachykinin NK(1)-receptors, and K(+)(ATP) channels. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20071201 |
| Involvement of glucose and ATP-sensitive potassium (K+) channels on morphine-induced conditioned place preference. | European journal of pharmacology 20071114 |
| Potassium channel openers accelerate epidermal barrier recovery. | The British journal of dermatology 20071101 |
| Gliclazide inhibits proliferation but stimulates differentiation of white and brown adipocytes. | Journal of biochemistry 20071101 |
| From hyperinsulinaemic hypoglycaemia to ketotic hypoglycaemia: the range of glucose abnormalities in patients born with intrauterine growth retardation. | European journal of pediatrics 20071001 |
| Role of insulin in the hyperandrogenemia of lean women with polycystic ovary syndrome and normal insulin sensitivity. | Fertility and sterility 20071001 |
| Resveratrol-induced inhibition of insulin secretion from rat pancreatic islets: evidence for pivotal role of metabolic disturbances. | American journal of physiology. Endocrinology and metabolism 20071001 |
| 5-Hydroxydecanoate inhibits proliferation of hypoxic human pulmonary artery smooth muscle cells by blocking mitochondrial K(ATP) channels. | Acta pharmacologica Sinica 20071001 |
| Cardioplegia and diazoxide modulate STAT3 activation and DNA binding. | The Annals of thoracic surgery 20071001 |
| Effective pharmacotherapy against oxidative injury: alternative utility of an ATP-sensitive potassium channel opener. | Journal of cardiovascular pharmacology 20071001 |
| Ischemic preconditioning: protection against myocardial necrosis and apoptosis. | Vascular health and risk management 20071001 |
| A review of pioglitazone HCL and glimepiride in the treatment of type 2 diabetes. | Vascular health and risk management 20071001 |
| Gonadotropin-releasing hormone neurons express K(ATP) channels that are regulated by estrogen and responsive to glucose and metabolic inhibition. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20070919 |
| Systemic administration of diazoxide induces delayed preconditioning against transient focal cerebral ischemia in rats. | Brain research 20070907 |
| The GluCre-ROSA26EYFP mouse: a new model for easy identification of living pancreatic alpha-cells. | FEBS letters 20070904 |
| In vitro evidences for glucosensing capacity and mechanisms in hypothalamus, hindbrain, and Brockmann bodies of rainbow trout. | American journal of physiology. Regulatory, integrative and comparative physiology 20070901 |
| Congenital hyperinsulinism associated ABCC8 mutations that cause defective trafficking of ATP-sensitive K+ channels: identification and rescue. | Diabetes 20070901 |
| Tissue-dependent loss of phosphofructokinase-M in mice with interrupted activity of the distal promoter: impairment in insulin secretion. | American journal of physiology. Endocrinology and metabolism 20070901 |
| Effects of washout following indomethacin administration on electrical field stimulation-induced isolated rat gastric fundus strip contractions. | Journal of gastroenterology and hepatology 20070901 |
| Maintenance of myocyte volume homeostasis during stress by diazoxide is cardioprotective. | The Annals of thoracic surgery 20070901 |
| Invited commentary. | The Annals of thoracic surgery 20070901 |
| Diazoxide is protective in the rat retina against ischemic injury induced by bilateral carotid occlusion and glutamate-induced degeneration. | Neurotoxicity research 20070901 |
| Adenosine and TNF-alpha exert similar inotropic effect on heart cultures, suggesting a cardioprotective mechanism against hypoxia. | Life sciences 20070816 |
| The actions of a novel potent islet beta-cell specific ATP-sensitive K+ channel opener can be modulated by syntaxin-1A acting on sulfonylurea receptor 1. | Diabetes 20070801 |
| Activation of alpha1B-adrenoceptors alleviates ischemia/reperfusion injury by limitation of mitochondrial Ca2+ overload in cardiomyocytes. | Cardiovascular research 20070801 |
| Preconditioning and postconditioning: the essential role of the mitochondrial permeability transition pore. | Cardiovascular research 20070801 |
| Iptakalim, a vascular ATP-sensitive potassium (KATP) channel opener, closes rat pancreatic beta-cell KATP channels and increases insulin release. | The Journal of pharmacology and experimental therapeutics 20070801 |
| Single residue (K332A) substitution in Kir6.2 abolishes the stimulatory effect of long-chain acyl-CoA esters: indications for a long-chain acyl-CoA ester binding motif. | Diabetologia 20070801 |
| A novel mutation associated with congenital hyperinsulinism. | American journal of perinatology 20070801 |
| A randomised comparison of hydralazine and mini-bolus diazoxide for hypertensive emergencies in pregnancy: the PIVOT trial. | The Australian & New Zealand journal of obstetrics & gynaecology 20070801 |
| The role of mitochondria in protection of the heart by preconditioning. | Biochimica et biophysica acta 20070801 |
| Development of pulmonary hypertension in an infant treated with diazoxide. | Journal of pediatric endocrinology & metabolism : JPEM 20070801 |
| [Protection mechanisms of ATP-sensitive K channels on hippocampal CA1 neurons during chronic severe hypoxia]. | Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20070801 |
| NO mobilizes intracellular Zn2+ via cGMP/PKG signaling pathway and prevents mitochondrial oxidant damage in cardiomyocytes. | Cardiovascular research 20070715 |
| Lack of effect of short-term diazoxide administration on luteinizing hormone secretion in women with polycystic ovary syndrome. | Fertility and sterility 20070701 |
| ATP-sensitive potassium channel: a novel target for protection against UV-induced human skin cell damage. | Journal of cellular physiology 20070701 |
| Transgenic expression of a dominant negative K(ATP) channel subunit in the mouse endothelium: effects on coronary flow and endothelin-1 secretion. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070701 |
| Mitochondrial Ca2+-activated K+ channels more efficiently reduce mitochondrial Ca2+ overload in rat ventricular myocytes. | American journal of physiology. Heart and circulatory physiology 20070701 |
| Intermittent activation of bradykinin B2 receptors and mitochondrial KATP channels trigger cardiac postconditioning through redox signaling. | Cardiovascular research 20070701 |
| No effect of inhibition of insulin secretion by diazoxide on weight loss in hyperinsulinaemic obese subjects during an 8-week weight-loss diet. | Diabetes, obesity & metabolism 20070701 |
| ATP-sensitive potassium channel in mitochondria of the eukaryotic microorganism Acanthamoeba castellanii. | The Journal of biological chemistry 20070615 |
| Metabolic and ionic coupling factors in amino acid-stimulated insulin release in pancreatic beta-HC9 cells. | American journal of physiology. Endocrinology and metabolism 20070601 |
| Regulation of KATP channel subunit gene expression by hyperglycemia in the mediobasal hypothalamus of female rats. | American journal of physiology. Endocrinology and metabolism 20070601 |
| A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans. | PLoS biology 20070601 |
| Expression and function of ATP-dependent potassium channels in late post-infarction remodeling. | Journal of molecular and cellular cardiology 20070601 |
| Metastatic insulinoma in an adult patient with underlying nesidioblastosis. | Journal of endocrinological investigation 20070601 |
| Changes in rat myocardium associated with modulation of ischemic tolerance by diazoxide. | General physiology and biophysics 20070601 |
| Glucose and hippocampal neuronal excitability: role of ATP-sensitive potassium channels. | Journal of neuroscience research 20070515 |
| ATP-sensitive potassium currents reduce the PGE2-mediated enhancement of excitability in adult rat sensory neurons. | Brain research 20070511 |
| Effects of propofol on intracellular Ca2+ homeostasis in human astrocytoma cells. | Brain research 20070511 |
| Virtual screening for novel openers of pancreatic K(ATP) channels. | Journal of medicinal chemistry 20070503 |
| Oleic acid glucose-independently stimulates glucagon secretion by increasing cytoplasmic Ca2+ via endoplasmic reticulum Ca2+ release and Ca2+ influx in the rat islet alpha-cells. | Endocrinology 20070501 |
| The role of adenosine triphosphate-regulated potassium channels in propofol-induced beneficial effect on contractile function of hypercholesterolemic isolated rabbit hearts. | Saudi medical journal 20070501 |
| [Effect of opening of mitochondrial ATP-sensitive K(+) channels on the expression of hypoxia inducible factor-1alpha and cell proliferation in pulmonary arterial smooth muscle cells of rats]. | Sheng li xue bao : [Acta physiologica Sinica] 20070425 |
| Effects of diazoxide on gene expression in rat pancreatic islets are largely linked to elevated glucose and potentially serve to enhance beta-cell sensitivity. | Diabetes 20070401 |
| ATP-sensitive K(+) channels regulate the release of GABA in the ventromedial hypothalamus during hypoglycemia. | Diabetes 20070401 |
| Mitochondrial ATP-sensitive K+ channels are redox-sensitive pathways that control reactive oxygen species production. | Free radical biology & medicine 20070401 |
| beta-cell failure in diabetes and preservation by clinical treatment. | Endocrine reviews 20070401 |
| R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion. | Nature cell biology 20070401 |
| Macrosomia and hyperinsulinaemic hypoglycaemia in patients with heterozygous mutations in the HNF4A gene. | PLoS medicine 20070401 |
| Drug-induced pulmonary hypertension in newborns: a review. | Current vascular pharmacology 20070401 |
| Extemporaneous compounding in a sample of New Zealand hospitals: a retrospective survey. | The New Zealand medical journal 20070323 |
| Pharmacologically preconditioned skeletal myoblasts are resistant to oxidative stress and promote angiomyogenesis via release of paracrine factors in the infarcted heart. | Circulation research 20070302 |
| Functional genomics of the beta-cell: short-chain 3-hydroxyacyl-coenzyme A dehydrogenase regulates insulin secretion independent of K+ currents. | Molecular endocrinology (Baltimore, Md.) 20070301 |
| Age- and gender-related differences in mitochondrial oxygen consumption and calcium with cardioplegia and diazoxide. | The Annals of thoracic surgery 20070301 |
| Invited commentary. | The Annals of thoracic surgery 20070301 |
| Diazoxide, as a postconditioning and delayed preconditioning trigger, increases HSP25 and HSP70 in the central nervous system following combined cerebral stroke and hemorrhagic shock. | Journal of neurotrauma 20070301 |
| Involvement of ATP-sensitive potassium channels in proliferation and differentiation of rat preadipocytes. | Sheng li xue bao : [Acta physiologica Sinica] 20070225 |
| Pharmacological and molecular characterization of ATP-sensitive K(+) conductances in CART and NPY/AgRP expressing neurons of the hypothalamic arcuate nucleus. | Neuroscience 20070209 |
| The mitochondrial K(ATP) channel opener BMS-191095 reduces neuronal damage after transient focal cerebral ischemia in rats. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070201 |
| Myocardial preconditioning against ischemia-reperfusion injury is abolished in Zucker obese rats with insulin resistance. | American journal of physiology. Regulatory, integrative and comparative physiology 20070201 |
| Preconditioning protects endothelium by preventing ET-1-induced activation of NADPH oxidase and xanthine oxidase in post-ischemic heart. | Journal of molecular and cellular cardiology 20070201 |
| Electrophysiological and pharmacological characterization of the K(ATP) channel involved in the K+-current responses to FSH and adenosine in the follicular cells of Xenopus oocyte. | The journal of physiological sciences : JPS 20070201 |
| Twelve weeks' treatment with diazoxide without insulin supplementation in Type 2 diabetes is feasible but does not improve insulin secretion. | Diabetic medicine : a journal of the British Diabetic Association 20070201 |
| The possible mechanisms by which phanoside stimulates insulin secretion from rat islets. | The Journal of endocrinology 20070201 |
| Downmodulation of mitochondrial F0F1 ATP synthase by diazoxide in cardiac myoblasts: a dual effect of the drug. | American journal of physiology. Heart and circulatory physiology 20070201 |
| Role of NO/cGMP/KATP pathway in antinociceptive effect of sildenafil in zymosan writhing response in mice. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20070201 |
| [Effect of activation of mitochondrial ATP sensitive potassium channel and calcium activated potassium channel on the permeability transition of mitochondria from both normal and ischemic rat brain]. | Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20070201 |
| Identification of two types of ATP-sensitive K+ channels in rat ventricular myocytes. | Life sciences 20070102 |
| Nicorandil opens mitochondrial K(ATP) channels not only directly but also through a NO-PKG-dependent pathway. | Basic research in cardiology 20070101 |
| Distinct KATP channels mediate the antihypertrophic effects of adenosine receptor activation in neonatal rat ventricular myocytes. | The Journal of pharmacology and experimental therapeutics 20070101 |
| Diazoxide prevents diabetes through inhibiting pancreatic beta-cells from apoptosis via Bcl-2/Bax rate and p38-beta mitogen-activated protein kinase. | Endocrinology 20070101 |
| Antagonism of the insulinotropic action of first generation imidazolines by openers of K(ATP) channels. | Biochemical pharmacology 20070101 |
| Diazoxide-induced respiratory inhibition - a putative mitochondrial K(ATP) channel independent mechanism of pharmacological preconditioning. | Molecular and cellular biochemistry 20070101 |
| Insulin secretory actions of extracts of Asparagus racemosus root in perfused pancreas, isolated islets and clonal pancreatic beta-cells. | The Journal of endocrinology 20070101 |
| Severe paraneoplastic hypoglycemia in a patient with a gastrointestinal stromal tumor with an exon 9 mutation: a case report. | BMC cancer 20070101 |
| Involvement of alpha-receptors and potassium channels in the mechanism of action of sildenafil citrate. | International journal of impotence research 20070101 |
| Effect of diazoxide and Ca2+ on rat heart mitochondria loaded with Na+. | Doklady. Biochemistry and biophysics 20070101 |
| Involvement of SH-groups during interaction of diazoxide with the inner membrane of rat heart mitochondria. | Doklady. Biochemistry and biophysics 20070101 |
| Rapid intraoperative insulin assay: a novel method to differentiate insulinoma from nesidioblastosis in the pediatric patient. | Annals of surgical innovation and research 20070101 |
| NFU-Enabled FASTA: moving bioinformatics applications onto wide area networks. | Source code for biology and medicine 20070101 |
| Serofendic acid, a substance extracted from fetal calf serum, as a novel drug for cardioprotection. | Cardiovascular drug reviews 20070101 |
| Pitfalls in diagnosing a small cystic insulinoma: a case report. | Journal of medical case reports 20070101 |
| Pharmacological preconditioning with diazoxide slows energy metabolism during sustained ischemia. | Experimental and clinical cardiology 20070101 |
| New benzopyran-based openers of the mitochondrial ATP-sensitive potassium channel with potent anti-ischemic properties. | Journal of medicinal chemistry 20061228 |
| Glucose and insulin synergistically activate phosphatidylinositol 3-kinase to trigger oscillations of phosphatidylinositol 3,4,5-trisphosphate in beta-cells. | The Journal of biological chemistry 20061222 |
| Influence of ATP-dependent K+ channels on nicotine-induced inhibition of withdrawal in morphine-dependent mice. | European journal of pharmacology 20061215 |
| Diazoxide acts more as a PKC-epsilon activator, and indirectly activates the mitochondrial K(ATP) channel conferring cardioprotection against hypoxic injury. | British journal of pharmacology 20061201 |
| The atypical antipsychotic clozapine impairs insulin secretion by inhibiting glucose metabolism and distal steps in rat pancreatic islets. | Diabetologia 20061201 |
| Nutrient control of insulin secretion in isolated normal human islets. | Diabetes 20061201 |
| Contribution of calcium influx in mediating glucose-stimulated oxygen consumption in pancreatic islets. | Diabetes 20061201 |
| Ischemic preconditioning prevents endothelial dysfunction, P-selectin expression, and neutrophil adhesion by preventing endothelin and O2- generation in the post-ischemic guinea-pig heart. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20061201 |
| Mosaic Turner syndrome and hyperinsulinaemic hypoglycaemia. | Journal of pediatric endocrinology & metabolism : JPEM 20061201 |
| Hypoglycemia in the neonate. | Pediatric endocrinology reviews : PER 20061201 |
| Diabetes and hypoglycaemia in young children and mutations in the Kir6.2 subunit of the potassium channel: therapeutic consequences. | Diabetes & metabolism 20061201 |
| Stimulus-secretion coupling of hypotonicity-induced insulin release in BRIN-BD11 cells. | Endocrine 20061201 |
| K+ channels involved in contractility of rabbit small intestine. | Journal of physiology and biochemistry 20061201 |
| Influence of ATP-sensitive potassium channels on lithium state-dependent memory of passive avoidance in mice. | European journal of pharmacology 20061121 |
| Iptakalim protects PC12 cell against H2O2-induced oxidative injury via opening mitochondrial ATP-sensitive potassium channel. | Biochemical and biophysical research communications 20061117 |
| Opening mitoKATP increases superoxide generation from complex I of the electron transport chain. | American journal of physiology. Heart and circulatory physiology 20061101 |
| Mechanism of reactive oxygen species generation after opening of mitochondrial KATP channels. | American journal of physiology. Heart and circulatory physiology 20061101 |
| Mitochondrial uncoupling, with low concentration FCCP, induces ROS-dependent cardioprotection independent of KATP channel activation. | Cardiovascular research 20061101 |
| FCCP is cardioprotective at concentrations that cause mitochondrial oxidation without detectable depolarisation. | Cardiovascular research 20061101 |
| Actions of ZD0947, a novel ATP-sensitive K+ channel opener, on membrane currents in human detrusor myocytes. | British journal of pharmacology 20061101 |
| Clinical features and morphological characterization of 10 patients with noninsulinoma pancreatogenous hypoglycaemia syndrome (NIPHS). | Clinical endocrinology 20061101 |
| Prolonged hyperinsulinaemic hypoglycaemia in newborns with intrauterine growth retardation. | Archives of disease in childhood. Fetal and neonatal edition 20061101 |
| European Academy of Paediatrics, Barcelona, Spain, October 7-10, 2006. Abstracts. | European journal of pediatrics 20061101 |
| [The effect of mitochondrial membrane potential on changes of reactive oxygen species and on proliferation of hypoxic human pulmonary arterial smooth muscle cells]. | Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20061101 |
| Diazoxide-induced cardioprotection via DeltaPsim loss depending on timing of application. | Life sciences 20061012 |
| LPS from Escherichia coli protects against indomethacin-induced gastropathy in rats--role of ATP-sensitive potassium channels. | European journal of pharmacology 20061010 |
| First molecular evidence that inositol trisphosphate signaling contributes to infarct size reduction with preconditioning. | American journal of physiology. Heart and circulatory physiology 20061001 |
| Iptakalim modulates ATP-sensitive K(+) channels in dopamine neurons from rat substantia nigra pars compacta. | The Journal of pharmacology and experimental therapeutics 20061001 |
| C16:0 sulfatide inhibits insulin secretion in rat beta-cells by reducing the sensitivity of KATP channels to ATP inhibition. | Diabetes 20061001 |
| Hyperlipidemic mice present enhanced catabolism and higher mitochondrial ATP-sensitive K+ channel activity. | Gastroenterology 20061001 |
| Pancreatic islets from hypothalamic obese rats maintain K+ATP channel-dependent but not -independent pathways on glucose-induced insulin release process. | Endocrine 20061001 |
| Proteomic analysis of pharmacological preconditioning: novel protein targets converge to mitochondrial metabolism pathways. | Circulation research 20060929 |
| Diazoxide protects against methylmalonate-induced neuronal toxicity. | Experimental neurology 20060901 |
| Diazoxide preconditioning alleviates apoptosis of hippocampal neurons induced by anoxia-reoxygenation in vitro through up-regulation of Bcl-2/Bax protein ratio. | Sheng li xue bao : [Acta physiologica Sinica] 20060825 |
| K+-independent actions of diazoxide question the role of inner membrane KATP channels in mitochondrial cytoprotective signaling. | The Journal of biological chemistry 20060818 |
| The diagnosis of ectopic focal hyperinsulinism of infancy with [18F]-dopa positron emission tomography. | The Journal of clinical endocrinology and metabolism 20060801 |
| K+-ATP-channel-related protein complexes: potential transducers in the regulation of epithelial tight junction permeability. | Journal of cell science 20060801 |
| Total cellular calcium and magnesium content of cultured human peripheral blood mononuclear cells following exposure to antidiabetic drugs. | Acta diabetologica 20060801 |
| Paradoxical stimulation of glucagon secretion by high glucose concentrations. | Diabetes 20060801 |
| First phase of glucose-stimulated insulin secretion from MIN 6 cells does not always require extracellular calcium influx. | Journal of pharmacological sciences 20060801 |
| Hypertrichosis lanuginosa acquisita associated with autoimmune hepatitis. | The Journal of dermatology 20060801 |
| Recurrent hyperinsulinemic hypoglycemia caused by an insulin-secreting insulinoma. | Nature clinical practice. Endocrinology & metabolism 20060801 |
| [Role of gap junction in ischemic preconditioning]. | Zhonghua xin xue guan bing za zhi 20060801 |
| Hyperinsulinism in infancy--genetic aspects. | Pediatric endocrinology reviews : PER 20060801 |
| The mechanism by which the mitochondrial ATP-sensitive K+ channel opening and H2O2 inhibit the mitochondrial permeability transition. | The Journal of biological chemistry 20060728 |
| Design, synthesis, and pharmacological evaluation of R/S-3,4-dihydro-2,2-dimethyl- 6-halo-4-(phenylaminocarbonylamino)-2H-1-benzopyrans: toward tissue-selective pancreatic beta-cell KATP channel openers structurally related to (+/-)-cromakalim. | Journal of medicinal chemistry 20060727 |
| It is AMPA receptor, not kainate receptor, that contributes to the NBQX-induced antinociception in the spinal cord of rats. | Brain research 20060719 |
| Drugs for treatment of very high blood pressure during pregnancy. | The Cochrane database of systematic reviews 20060719 |
| New 3-alkylamino-4H-thieno-1,2,4-thiadiazine 1,1-dioxide derivatives activate ATP-sensitive potassium channels of pancreatic beta cells. | Journal of medicinal chemistry 20060713 |
| The neuroprotection conferred by activating the mitochondrial ATP-sensitive K+ channel is mediated by inhibiting the mitochondrial permeability transition pore. | Neuroscience letters 20060710 |
| Translocation of connexin 43 to the inner mitochondrial membrane of cardiomyocytes through the heat shock protein 90-dependent TOM pathway and its importance for cardioprotection. | Circulation research 20060707 |
| Regulation of plasma vasopressin and renin activity in conscious hindlimb-unloaded rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20060701 |
| A novel approach to assess insulin sensitivity reveals no increased insulin sensitivity in mice with a dominant-negative mutant hepatocyte nuclear factor-1alpha. | American journal of physiology. Regulatory, integrative and comparative physiology 20060701 |
| Intravenous 6-hydroxydopamine attenuates vasopressin and oxytocin secretion stimulated by hemorrhage and hypotension but not hyperosmolality in rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20060701 |
| No loss of cardioprotection by postconditioning in connexin 43-deficient mice. | Basic research in cardiology 20060701 |
| Intracellular ATP-sensitive K+ channels in mouse pancreatic beta cells: against a role in organelle cation homeostasis. | Diabetologia 20060701 |
| Age- and gender-related differences in ischemia/reperfusion injury and cardioprotection: effects of diazoxide. | The Annals of thoracic surgery 20060701 |
| ATP-sensitive potassium channels mediate the anti-ischemic properties of ischemic and pharmacologic preconditioning in rat random-pattern skin flap. | Annals of plastic surgery 20060701 |
| [Effect of opening of mitochondrial ATP-sensitive K⁺ channel on the distribution of cytochrome C and on proliferation of human pulmonary arterial smooth muscle cells in hypoxia]. | Sheng li xue bao : [Acta physiologica Sinica] 20060625 |
| Selective inhibition of pinacidil effects by estrogen in guinea pig heart. | International journal of cardiology 20060607 |
| Diazoxide preconditioning plus subsequent hypothermia increased resistance of rat cultured hippocampal neurons against hypoxia-reoxygenation injury. | Chinese medical journal 20060605 |
| Levosimendan protects against experimental endotoxemic acute renal failure. | American journal of physiology. Renal physiology 20060601 |
| Diphenylhydantoin suppresses glucose-induced insulin release by decreasing cytoplasmic H+ concentration in pancreatic islets. | Endocrinology 20060601 |
| Cardiac protection by mitoKATP channels is dependent on Akt translocation from cytosol to mitochondria during late preconditioning. | American journal of physiology. Heart and circulatory physiology 20060601 |
| EUS-guided alcohol ablation of an insulinoma. | Gastrointestinal endoscopy 20060601 |
| The effect of pre- and posttreatment with diazoxide on the early phase of chronic cerebral hypoperfusion in the rat. | Brain research 20060504 |
| Serofendic acid, a novel substance extracted from fetal calf serum, protects against oxidative stress in neonatal rat cardiac myocytes. | Journal of the American College of Cardiology 20060502 |
| Nitric oxide-cGMP-protein kinase G signaling pathway induces anoxic preconditioning through activation of ATP-sensitive K+ channels in rat hearts. | American journal of physiology. Heart and circulatory physiology 20060501 |
| Characterization of human cardiac mitochondrial ATP-sensitive potassium channel and its regulation by phorbol ester in vitro. | American journal of physiology. Heart and circulatory physiology 20060501 |
| Activation of ATP-sensitive K channels protects hippocampal CA1 neurons from hypoxia by suppressing p53 expression. | Neuroscience letters 20060501 |
| Combined modulation of the mitochondrial ATP-dependent potassium channel and the permeability transition pore causes prolongation of the biphasic calcium dynamics. | Cell calcium 20060501 |
| MitoKATP channel activation suppresses gap junction permeability in the ischemic myocardium by an ERK-dependent mechanism. | Cardiovascular research 20060501 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Antihypertensive drugs clonidine, diazoxide, hydralazine and furosemide regulate the production of cytokines by placentas and peripheral blood mononuclear cells in normal pregnancy. | Journal of hypertension 20060501 |
| Noninvasive assessment of brain injury in a canine model of hypothermic circulatory arrest using magnetic resonance spectroscopy. | The Annals of thoracic surgery 20060501 |
| Preservation of mitochondrial structure and function after cardioplegic arrest in the neonate using a selective mitochondrial KATP channel opener. | The Annals of thoracic surgery 20060501 |
| A mysterious case of normalising blood sugar: insulinoma in a long-standing diabetic patient. | Age and ageing 20060501 |
| Mitochondrial potassium ATP channels and retinal ischemic preconditioning. | Investigative ophthalmology & visual science 20060501 |
| L-cysteine inhibits insulin release from the pancreatic beta-cell: possible involvement of metabolic production of hydrogen sulfide, a novel gasotransmitter. | Diabetes 20060501 |
| The mitochondrial K-ATP channel opener, diazoxide, prevents ischemia-reperfusion injury in the rabbit spinal cord. | The American journal of pathology 20060501 |
| Diazoxide provides maximal KATP channels independent protection if present throughout hypoxia. | The Annals of thoracic surgery 20060401 |
| Invited commentary. | The Annals of thoracic surgery 20060401 |
| Data and animal management software for large-scale phenotype screening. | Mammalian genome : official journal of the International Mammalian Genome Society 20060401 |
| Ocimum sanctum leaf extracts stimulate insulin secretion from perfused pancreas, isolated islets and clonal pancreatic beta-cells. | The Journal of endocrinology 20060401 |
| MitoK(ATP)-dependent changes in mitochondrial volume and in complex II activity during ischemic and pharmacological preconditioning of Langendorff-perfused rat heart. | Journal of bioenergetics and biomembranes 20060401 |
| Different effects of optical isomers of the 5-HT1A receptor antagonist pyrapyridolol against postischemic guinea-pig myocardial dysfunction and apoptosis through the mitochondrial permeability transition pore. | European journal of pharmacology 20060318 |
| Protein kinase G-induced activation of K(ATP) channels reduces contractility of human prostate tissue. | The Prostate 20060301 |
| Changes in membrane cholesterol of pituitary tumor (GH3) cells regulate the activity of large-conductance Ca2+-activated K+ channels. | The Chinese journal of physiology 20060227 |
| Pharmacological characterization of urinary bladder smooth muscle contractility following partial bladder outlet obstruction in pigs. | European journal of pharmacology 20060217 |
| The nitric oxide-cyclic GMP-protein kinase G-K+ channel pathway participates in the antiallodynic effect of spinal gabapentin. | European journal of pharmacology 20060215 |
| The regulation of rotenone-induced inflammatory factor production by ATP-sensitive potassium channel expressed in BV-2 cells. | Neuroscience letters 20060213 |
| Glucose-stimulated DNA synthesis through mammalian target of rapamycin (mTOR) is regulated by KATP channels: effects on cell cycle progression in rodent islets. | The Journal of biological chemistry 20060210 |
| A novel KCNJ11 mutation associated with congenital hyperinsulinism reduces the intrinsic open probability of beta-cell ATP-sensitive potassium channels. | The Journal of biological chemistry 20060203 |
| Activation of mitochondrial ATP-sensitive potassium channels improves rotenone-related motor and neurochemical alterations in rats. | The international journal of neuropsychopharmacology 20060201 |
| Mitochondrial dysfunction as the cause of the failure to precondition the diabetic human myocardium. | Cardiovascular research 20060201 |
| Ischemic preconditioning requires increases in reactive oxygen release independent of mitochondrial K+ channel activity. | Free radical biology & medicine 20060201 |
| Clinical features and insulin regulation in infants with a syndrome of prolonged neonatal hyperinsulinism. | The Journal of pediatrics 20060201 |
| P-1075 exerts diverse modulatory effects on mitochondrial ATP-sensitive K+ channels in rabbit ventricular myocytes. | Journal of cardiovascular pharmacology 20060201 |
| A rare case of adult-onset nesidioblastosis treated successfully with diazoxide. | Endocrine journal 20060201 |
| [The effects of diazoxide on myocardium function and the expressions of ERK and JNK in isolated spontaneous hypertension rat hearts]. | Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20060201 |
| KATP channels in mouse spermatogenic cells and sperm, and their role in capacitation. | Developmental biology 20060115 |
| Acute and chronic effects of glucose and carbachol on insulin secretion and phospholipase C activation: studies with diazoxide and atropine. | American journal of physiology. Endocrinology and metabolism 20060101 |
| Initiation of remote microvascular preconditioning requires K(ATP) channel activity. | American journal of physiology. Heart and circulatory physiology 20060101 |
| Non-beating HL-1 cells for confocal microscopy: application to mitochondrial functions during cardiac preconditioning. | Progress in biophysics and molecular biology 20060101 |
| The direct physiological effects of mitoK(ATP) opening on heart mitochondria. | American journal of physiology. Heart and circulatory physiology 20060101 |
| Role of the sarcolemmal adenosine triphosphate-sensitive potassium channel in hyperkalemic cardioplegia-induced myocyte swelling and reduced contractility. | The Annals of thoracic surgery 20060101 |
| Hyperkalemic cardioplegia-induced myocyte swelling and contractile dysfunction: prevention by diazoxide. | The Annals of thoracic surgery 20060101 |
| Effect of phosphodiesterase 5 inhibitor on alteration in vascular smooth muscle sensitivity and renal function in rats with liver cirrhosis. | American journal of physiology. Heart and circulatory physiology 20060101 |
| Effects of sulfonylureas on mitochondrial ATP-sensitive K+ channels in cardiac myocytes: implications for sulfonylurea controversy. | Diabetes/metabolism research and reviews 20060101 |
| Possible role of potassium channel, big K in etiology of schizophrenia. | Medical hypotheses 20060101 |
| Towards selective Kir6.2/SUR1 potassium channel openers, medicinal chemistry and therapeutic perspectives. | Current medicinal chemistry 20060101 |
| Complete clinical remission and disappearance of liver metastases after treatment with somatostatin analogue in a 40-year-old woman with a malignant insulinoma positive for somatostatin receptors type 2. | Hormone research 20060101 |
| Ischemic preconditioning: a novel target for neuroprotective therapy. | Cerebrovascular diseases (Basel, Switzerland) 20060101 |
| [Pitfalls in the diagnosis of congenital hyperinsulinism: a case report and review of the literature]. | Klinische Padiatrie 20060101 |
| Comparative proteomics analysis of differentially expressed phosphoproteins in adult rat ventricular myocytes subjected to diazoxide preconditioning. | Drug metabolism and drug interactions 20060101 |
| [The influence of the fluorine-containing activators of mitochondrial adenosine triphosphate sensitive potassium channels on the oxidative phosphorilation]. | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20060101 |
| Study of the mechanism of action of diazoxide on rat heart mitochondria under calcium loading. | Doklady. Biochemistry and biophysics 20060101 |
| Cardioprotective effects of diazoxide on myocardial ischemia/reperfusion injury in rats. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20060101 |
| A role of opening of mitochondrial ATP-sensitive potassium channels in the infarct size-limiting effect of ischemic preconditioning via activation of protein kinase C in the canine heart. | Biochemical and biophysical research communications 20051223 |
| Costello syndrome and hyperinsulinemic hypoglycemia. | American journal of medical genetics. Part A 20051215 |
| [Diazoxide preconditioning combined with subsequent hypothermia alleviates anoxia-re-oxygenation injury: experiment with rat hippocampal neurons]. | Zhonghua yi xue za zhi 20051207 |
| Activation of KATP channels by H2S in rat insulin-secreting cells and the underlying mechanisms. | The Journal of physiology 20051201 |
| Diazoxide attenuates insulin secretion and hepatic lipogenesis in zucker diabetic fatty rats. | Medical science monitor : international medical journal of experimental and clinical research 20051201 |
| Glucose stimulates glucagon release in single rat alpha-cells by mechanisms that mirror the stimulus-secretion coupling in beta-cells. | Endocrinology 20051101 |
| Late preconditioning with isoflurane in cultured rat cortical neurones. | British journal of anaesthesia 20051101 |
| Severe hypoglycaemia post-gastric bypass requiring partial pancreatectomy: evidence for inappropriate insulin secretion and pancreatic islet hyperplasia. | Diabetologia 20051101 |
| [Congenital hyperinsulinism in newborn and infant]. | Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20051101 |
| Activation of ATP-sensitive K+ channels in the ventromedial hypothalamus amplifies counterregulatory hormone responses to hypoglycemia in normal and recurrently hypoglycemic rats. | Diabetes 20051101 |
| Synaptic activity becomes excitotoxic in neurons exposed to elevated levels of platelet-activating factor. | The Journal of clinical investigation 20051101 |
| Persistent hyperinsulinaemic hypoglycaemia of infancy: 15 years' experience at the Royal Children's Hospital (RCH), Melbourne. | Journal of pediatric endocrinology & metabolism : JPEM 20051101 |
| Characterization of K(ATP)-channels in rat basilar and middle cerebral arteries: studies of vasomotor responses and mRNA expression. | European journal of pharmacology 20051031 |
| Post-ischemic administration of diazoxide attenuates long-term microglial activation in the rat brain after permanent carotid artery occlusion. | Neuroscience letters 20051028 |
| Antidiabetic activity and toxicity of Zizyphus spina-christi leaves. | Journal of ethnopharmacology 20051003 |
| Lack of manifestations of diazoxide/5-hydroxydecanoate-sensitive KATP channel in rat brain nonsynaptosomal mitochondria. | The Journal of physiology 20051001 |
| Transgenic overexpression of SUR1 in the heart suppresses sarcolemmal K(ATP). | Journal of molecular and cellular cardiology 20051001 |
| Feedback activation of phospholipase C via intracellular mobilization and store-operated influx of Ca2+ in insulin-secreting beta-cells. | Journal of cell science 20051001 |
| Sulphonylurea sensitivity and enriched expression implicate inward rectifier K+ channels in Drosophila melanogaster renal function. | The Journal of experimental biology 20051001 |
| Multiple treatment approach to limit cardiac ischemia-reperfusion injury. | The Annals of thoracic surgery 20051001 |
| Invited commentary. | The Annals of thoracic surgery 20051001 |
| Serum glucagon counterregulatory hormonal response to hypoglycemia is blunted in congenital hyperinsulinism. | Diabetes 20051001 |
| [Effects of iptakalim on intracellular calcium concentrations, PKA and PKC activities in rat tail artery smooth muscle cells]. | Yao xue xue bao = Acta pharmaceutica Sinica 20051001 |
| Impairment of diazoxide-induced formation of reactive oxygen species and loss of cardioprotection in connexin 43 deficient mice. | Circulation research 20050916 |
| Sulphonylurea receptors differently modulate ICC pacemaker Ca2+ activity and smooth muscle contractility. | Journal of cell science 20050915 |
| Effect of indomethacin on electrical field stimulation-induced contractions of isolated transverse and longitudinal rat gastric fundus strips. | World journal of gastroenterology 20050914 |
| Different actions of cardioprotective agents on mitochondrial Ca2+ regulation in a Ca2+ paradox-induced Ca2+ overload. | Circulation journal : official journal of the Japanese Circulation Society 20050901 |
| Gestational change of K+ channel opener effect is correlated with the expression of uterine KATP channel subunits. | European journal of obstetrics, gynecology, and reproductive biology 20050901 |
| Myocyte volume and function in response to osmotic stress: observations in the presence of an adenosine triphosphate-sensitive potassium channel opener. | Circulation 20050830 |
| Mitochondria-derived reactive oxygen species dilate cerebral arteries by activating Ca2+ sparks. | Circulation research 20050819 |
| Protein kinase G transmits the cardioprotective signal from cytosol to mitochondria. | Circulation research 20050819 |
| Identification of N-arachidonylglycine, U18666A, and 4-androstene-3,17-dione as novel insulin Secretagogues. | Biochemical and biophysical research communications 20050805 |
| Processing of pro-islet amyloid polypeptide in the constitutive and regulated secretory pathways of beta cells. | Molecular endocrinology (Baltimore, Md.) 20050801 |
| Integrated pharmacological preconditioning and memory of cardioprotection: role of protein kinase C and phosphatidylinositol 3-kinase. | American journal of physiology. Heart and circulatory physiology 20050801 |
| Metamizol acts as an ATP sensitive potassium channel opener to inhibit the contracting response induced by angiotensin II but not to norepinephrine in rat thoracic aorta smooth muscle. | Vascular pharmacology 20050801 |
| Low doses of bisphenol A and diethylstilbestrol impair Ca2+ signals in pancreatic alpha-cells through a nonclassical membrane estrogen receptor within intact islets of Langerhans. | Environmental health perspectives 20050801 |
| MitoKATP-channel opener protects against neuronal death in rat venous ischemia. | Neurosurgery 20050801 |
| Effects of ATP-sensitive potassium channel activators diazoxide and BMS-191095 on membrane potential and reactive oxygen species production in isolated piglet mitochondria. | Brain research bulletin 20050730 |
| 3-Alkylamino-4H-1,2,4-benzothiadiazine 1,1-dioxides as ATP-sensitive potassium channel openers: effect of 6,7-disubstitution on potency and tissue selectivity. | Journal of medicinal chemistry 20050728 |
| Diazoxide preconditioning attenuates global cerebral ischemia-induced blood-brain barrier permeability. | Brain research 20050727 |
| Malignant insulinoma: spectrum of unusual clinical features. | Cancer 20050715 |
| Adenosine and ATP-sensitive potassium channels modulate dopamine release in the anoxic turtle (Trachemys scripta) striatum. | American journal of physiology. Regulatory, integrative and comparative physiology 20050701 |
| Diazoxide preserves hypercapnia-induced arteriolar vasodilation after global cerebral ischemia in piglets. | American journal of physiology. Heart and circulatory physiology 20050701 |
| K(ATP) channels and preconditioning: a re-examination of the role of mitochondrial K(ATP) channels and an overview of alternative mechanisms. | Journal of molecular and cellular cardiology 20050701 |
| Mitochondrial K(ATP) channels in cell survival and death. | Journal of molecular and cellular cardiology 20050701 |
| Cardioprotective effects of K ATP channel activation during hypoxia in goldfish Carassius auratus. | The Journal of experimental biology 20050701 |
| Probing of specific binding of synthetic sulfonylurea with the insulinoma cell line MIN6. | Journal of biochemistry 20050701 |
| [Protective effect of mitochondrial ATP-sensitive potassium channel opener on rat heart during hypothermic preservation]. | Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20050701 |
| Role of adenosine A1 and A3 receptors in regulation of cardiomyocyte homeostasis after mitochondrial respiratory chain injury. | American journal of physiology. Heart and circulatory physiology 20050601 |
| Ketotic hypoglycaemia in children with diazoxide responsive hyperinsulinism of infancy. | European journal of pediatrics 20050601 |
| SUR, ABC proteins targeted by KATP channel openers. | Journal of molecular and cellular cardiology 20050601 |
| Mitochondria and ischemia/reperfusion injury. | Annals of the New York Academy of Sciences 20050601 |
| Effect on K(ATP) channel activation properties and tissue selectivity of the nature of the substituent in the 7- and the 3-position of 4H-1,2,4-benzothiadiazine 1,1-dioxides. | Journal of medicinal chemistry 20050519 |
| Reactive oxygen species mediate the neuroprotection conferred by a mitochondrial ATP-sensitive potassium channel opener during ischemia in the rat hippocampal slice. | Brain research 20050503 |
| Prostacyclin attenuates oxidative damage of myocytes by opening mitochondrial ATP-sensitive K+ channels via the EP3 receptor. | American journal of physiology. Heart and circulatory physiology 20050501 |
| Systematic administration of iptakalim, an ATP-sensitive potassium channel opener, prevents rotenone-induced motor and neurochemical alterations in rats. | Journal of neuroscience research 20050501 |
| Diazoxide-mediated insulin suppression in obese men: a dose-response study. | Diabetes, obesity & metabolism 20050501 |
| Effects of KATP channel modulation on myocardial glycogen content, lactate, and amino acids in nonischemic and ischemic rat hearts. | Journal of cardiovascular pharmacology 20050501 |
| The ATP-sensitive potassium channel blocker glibenclamide prevents renal ischemia/reperfusion injury in rats. | Kidney international 20050501 |
| 150-kD oxygen-regulated protein is an essential factor for insulin release. | Pancreas 20050501 |
| Alterations in net glucose uptake and in the pancreatic B-cell GLUT2 transporter induced by diazoxide and by secretory stimuli. | The Journal of endocrinology 20050501 |
| Hyperinsulinism of infancy associated with a novel splice site mutation in the SCHAD gene. | The Journal of pediatrics 20050501 |
| Endogenous hydrogen peroxide regulates the excitability of midbrain dopamine neurons via ATP-sensitive potassium channels. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050427 |
| Evidence that insulin secretion influences SNAP-25 through proteasomal activation. | Biochemical and biophysical research communications 20050415 |
| mitoKATP channel activation in the postanoxic developing heart protects E-C coupling via NO-, ROS-, and PKC-dependent pathways. | American journal of physiology. Heart and circulatory physiology 20050401 |
| Peptide blockers of PKG inhibit ROS generation by acetylcholine and bradykinin in cardiomyocytes but fail to block protection in the whole heart. | American journal of physiology. Heart and circulatory physiology 20050401 |
| Are one or two dangerous? Sulfonylurea exposure in toddlers. | The Journal of emergency medicine 20050401 |
| Genotypes of the pancreatic beta-cell K-ATP channel and clinical phenotypes of Japanese patients with persistent hyperinsulinaemic hypoglycaemia of infancy. | Clinical endocrinology 20050401 |
| Novel and established potassium channel openers stimulate hair growth in vitro: implications for their modes of action in hair follicles. | The Journal of investigative dermatology 20050401 |
| Glucose triggers protein kinase A-dependent insulin secretion in mouse pancreatic islets through activation of the K+ATP channel-dependent pathway. | European journal of endocrinology 20050401 |
| Pancreatic beta-cells expressing GLP-1 are resistant to the toxic effects of immunosuppressive drugs. | Journal of molecular endocrinology 20050401 |
| Mitochondrial ATP-sensitive K+ channels prevent oxidative stress, permeability transition and cell death. | Journal of bioenergetics and biomembranes 20050401 |
| Protective effects of sarpogrelate, a 5-HT2A antagonist, against postischemic myocardial dysfunction in guinea-pig hearts. | Molecular and cellular biochemistry 20050401 |
| Remote preconditioning reduces ischemic injury in the explanted heart by a KATP channel-dependent mechanism. | American journal of physiology. Heart and circulatory physiology 20050301 |
| Mitochondria-derived reactive oxygen species and vascular MAP kinases: comparison of angiotensin II and diazoxide. | Hypertension (Dallas, Tex. : 1979) 20050301 |
| Loss of the decrement in intraislet insulin plausibly explains loss of the glucagon response to hypoglycemia in insulin-deficient diabetes: documentation of the intraislet insulin hypothesis in humans. | Diabetes 20050301 |
| Differential effects of insulin and dietary amino acids on muscle protein synthesis in adult and old rats. | The Journal of physiology 20050215 |
| Calcium-activated potassium channel triggers cardioprotection of ischemic preconditioning. | The Journal of pharmacology and experimental therapeutics 20050201 |
| Genotype-phenotype correlations in children with congenital hyperinsulinism due to recessive mutations of the adenosine triphosphate-sensitive potassium channel genes. | The Journal of clinical endocrinology and metabolism 20050201 |
| Mitochondrial K(ATP) channels in respiratory neurons and their role in the hypoxic facilitation of rhythmic activity. | Brain research 20050201 |
| Diagnostic difficulties in long-standing insulinoma with near-normal plasma insulin levels. | Journal of endocrinological investigation 20050201 |
| 4,6-Disubstituted 2,2-dimethylchromans structurally related to the K(ATP) channel opener cromakalim: design, synthesis, and effect on insulin release and vascular tone. | Journal of medicinal chemistry 20050127 |
| Diazoxide and dimethyl sulphoxide alleviate experimental cerebral hypoperfusion-induced white matter injury in the rat brain. | Neuroscience letters 20050120 |
| Mitochondrial Ca2+-activated K+ channels in cardiac myocytes: a mechanism of the cardioprotective effect and modulation by protein kinase A. | Circulation 20050118 |
| Effect of mitochondrial KATP channel on voltage-gated K+ channel in 24 hour-hypoxic human pulmonary artery smooth muscle cells. | Chinese medical journal 20050105 |
| Activation of ATP-sensitive potassium channels prevents the cleavage of cytosolic mu-calpain and abrogates the elevation of nuclear c-Fos and c-Jun expressions after hypoxic-ischemia in neonatal rat brain. | Brain research. Molecular brain research 20050105 |
| Synthesis and pharmacological evaluation of 4H-1,4-benzothiazine-2-carbonitrile 1,1-dioxide and N-(2-cyanomethylsulfonylphenyl)acylamide derivatives as potential activators of ATP sensitive potassium channels. | Bioorganic & medicinal chemistry 20050103 |
| Mechanism, temporal patterns, and magnitudes of the metabolic responses to the KATP channel agonist diazoxide. | American journal of physiology. Endocrinology and metabolism 20050101 |
| Alterations of insulin secretion following long-term manipulation of ATP-sensitive potassium channels by diazoxide and nateglinide. | Biochemical pharmacology 20050101 |
| Immunolocalization of KATP channel subunits in mouse and rat cardiac myocytes and the coronary vasculature. | BMC physiology 20050101 |
| Contemporary strategies in the diagnosis and management of neonatal hyperinsulinaemic hypoglycaemia. | Early human development 20050101 |
| Hyperinsulinism in tyrosinaemia type I. | Journal of inherited metabolic disease 20050101 |
| Diazoxide ameliorates microcirculatory disturbances through PKC-dependent pathway in I/R-injured rat cremaster muscles. | Journal of biomedical science 20050101 |
| Fatality after deliberate ingestion of the pesticide rotenone: a case report. | Critical care (London, England) 20050101 |
| Severe hyperinsulinaemic hypoglycaemia in a baby born to a mother taking oral ritodrine therapy for preterm labour. | Hormone research 20050101 |
| Effect of the degree of ischaemic injury and reoxygenation time on the type of myocardial cell death in man: role of caspases. | BMC physiology 20050101 |
| Effects of diazoxide treatments on electrophysiologyic properties in guinea pig papillary muscles undergoing ischemia/reperfusion. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20050101 |
| ATP-sensitive potassium channel (KATP channel) expression in the normal canine pancreas and in canine insulinomas. | BMC veterinary research 20050101 |
| Neuroprotective effect of KR-31378, a novel potassium channel activator, on spinal cord ischemic injury in rabbits. | Journal of investigative surgery : the official journal of the Academy of Surgical Research 20050101 |
| Bench-to-bedside review: Antidotal treatment of sulfonylurea-induced hypoglycaemia with octreotide. | Critical care (London, England) 20050101 |
| Activation of Mitochondrial ATP-Sensitive Potassium Channel Contributes to Protective Effect in Prolonged Myocardial Preservation. | Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20050101 |
| Differing effects of cyclosporin a on swelling amplitude and time constant of mitochondria from normal and ischemic rat brain. | Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20050101 |
| Mitochondrial permeability transition dynamics: an indicator of mitochondrial potassium channel opener. | Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20050101 |
| Ischemic preconditioning and diazoxide limit mitochondrial Ca overload during ischemia/reperfusion: Role of reactive oxygen species. | Experimental and clinical cardiology 20050101 |
| 2-(4-Methoxyphenoxy)-5-nitro-N-(4-sulfamoylphenyl)benzamide activates Kir6.2/SUR1 K(ATP) channels. | Bioorganic & medicinal chemistry letters 20041206 |
| Short-term intermittent exposure to diazoxide improves functional performance of beta-cells in a high-glucose environment. | American journal of physiology. Endocrinology and metabolism 20041201 |
| Modulation of adipoinsular axis in prediabetic zucker diabetic fatty rats by diazoxide. | Endocrinology 20041201 |
| Effect of two amino acids in TM17 of Sulfonylurea receptor SUR1 on the binding of ATP-sensitive K+ channel modulators. | Diabetes 20041201 |
| Signaling elements involved in the metabolic regulation of mTOR by nutrients, incretins, and growth factors in islets. | Diabetes 20041201 |
| P2Y purinergic potentiation of glucose-induced insulin secretion and pancreatic beta-cell metabolism. | Diabetes 20041201 |
| Massive augmentation of stimulated insulin secretion induced by fatty acid-free BSA in rat pancreatic islets. | Diabetes 20041201 |
| Myocardial impairment in chronic hypoxia is abolished by short aeration episodes: involvement of K+ATP channels. | Experimental biology and medicine (Maywood, N.J.) 20041201 |
| Bimodal role of conventional protein kinase C in insulin secretion from rat pancreatic beta cells. | The Journal of physiology 20041115 |
| Testosterone induces cytoprotection by activating ATP-sensitive K+ channels in the cardiac mitochondrial inner membrane. | Circulation 20041109 |
| Diazoxide-mediated preconditioning against apoptosis involves activation of cAMP-response element-binding protein (CREB) and NFkappaB. | The Journal of biological chemistry 20041105 |
| Quinolizidine alkaloids isolated from Lupinus species enhance insulin secretion. | European journal of pharmacology 20041103 |
| Opening of Ca2+-activated K+ channels triggers early and delayed preconditioning against I/R injury independent of NOS in mice. | American journal of physiology. Heart and circulatory physiology 20041101 |
| Opening of mitochondrial KATP channels enhances cardioprotection through the modulation of mitochondrial matrix volume, calcium accumulation, and respiration. | American journal of physiology. Heart and circulatory physiology 20041101 |
| PKC-epsilon is upstream and PKC-alpha is downstream of mitoKATP channels in the signal transduction pathway of ischemic preconditioning of human myocardium. | American journal of physiology. Cell physiology 20041101 |
| Fluctuations in mitochondrial membrane potential in single isolated brain mitochondria: modulation by adenine nucleotides and Ca2+. | Biophysical journal 20041101 |
| Effect of diazoxide on regulation of vesicular and plasma membrane GABA transporter genes and proteins in hippocampus of rats subjected to picrotoxin-induced kindling. | Neuroscience research 20041101 |
| A new ATP-sensitive K+ channel-independent mechanism is involved in glucose-excited neurons of mouse arcuate nucleus. | Diabetes 20041101 |
| Palmitate stimulation of glucagon secretion in mouse pancreatic alpha-cells results from activation of L-type calcium channels and elevation of cytoplasmic calcium. | Diabetes 20041101 |
| Palmitoyl lysophosphatidylcholine mediated mobilization of LPL to the coronary luminal surface requires PKC activation. | Journal of molecular and cellular cardiology 20041101 |
| Inhibition of phenylephrine induced hypertrophy in rat neonatal cardiomyocytes by the mitochondrial KATP channel opener diazoxide. | Journal of molecular and cellular cardiology 20041101 |
| Selective arterial calcium stimulation and hepatic venous sampling in the evaluation of hyperinsulinemic hypoglycemia: potential and limitations. | Journal of vascular and interventional radiology : JVIR 20041101 |
| [Hyperinsulinism-hyperammonemia syndrome due to a de novo mutation in exon 7 (G979A) of the glutamate dehydrogenase gene with excellent response to diazoxide]. | Anales de pediatria (Barcelona, Spain : 2003) 20041101 |
| Medications used in the treatment of hypoglycemia due to congenital hyperinsulinism of infancy (HI). | Pediatric endocrinology reviews : PER 20041101 |
| [The protective effect of diazoxide on long-term heart preservation]. | Sheng li xue bao : [Acta physiologica Sinica] 20041025 |
| KATP channel activation induces ischemic preconditioning of the endothelium in humans in vivo. | Circulation 20041012 |
| Rebaudioside A potently stimulates insulin secretion from isolated mouse islets: studies on the dose-, glucose-, and calcium-dependency. | Metabolism: clinical and experimental 20041001 |
| Activation of the ATP-dependent potassium channel attenuates norepinephrine-induced vasoconstriction in the human forearm. | Shock (Augusta, Ga.) 20041001 |
| Quinones and aromatic chemical compounds in particulate matter induce mitochondrial dysfunction: implications for ultrafine particle toxicity. | Environmental health perspectives 20041001 |
| Insulin secretion is stimulated by ethanol extract of Anemarrhena asphodeloides in isolated islet of healthy Wistar and diabetic Goto-Kakizaki Rats. | Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20041001 |
| Persistent hyperinsulinemic hypoglycemia presenting with a rare complication: West syndrome. | Journal of pediatric endocrinology & metabolism : JPEM 20041001 |
| Does the mitochondrial permeability transition have a role in preconditioning? | Circulation 20040914 |
| Diazoxide prevents mitochondrial swelling and Ca2+ accumulation in CA1 pyramidal cells after cerebral ischemia in newborn pigs. | Brain research 20040903 |
| Contribution of Akt and endothelial nitric oxide synthase to diazoxide-induced late preconditioning. | American journal of physiology. Heart and circulatory physiology 20040901 |
| Potassium-specific effects of levosimendan on heart mitochondria. | Biochemical pharmacology 20040901 |
| Zinc inhibits glutamate release via activation of pre-synaptic K channels and reduces ischaemic damage in rat hippocampus. | Journal of neurochemistry 20040901 |
| Temporary preservation of beta-cell function by diazoxide treatment in childhood type 1 diabetes. | Diabetes care 20040901 |
| Glutamine potently stimulates glucagon-like peptide-1 secretion from GLUTag cells. | Diabetologia 20040901 |
| Endothelial protection from reperfusion injury by ischemic preconditioning and diazoxide involves a SOD-like anti-O2- mechanism. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20040901 |
| Atypical Ca2+-induced Ca2+ release from a sarco-endoplasmic reticulum Ca2+-ATPase 3-dependent Ca2+ pool in mouse pancreatic beta-cells. | The Journal of physiology 20040815 |
| Diazoxide and N omega-nitro-L-arginine counteracted A beta 1-42-induced cytotoxicity. | Neuroreport 20040806 |
| Preconditioning protects by inhibiting the mitochondrial permeability transition. | American journal of physiology. Heart and circulatory physiology 20040801 |
| Increased glucose sensitivity of both triggering and amplifying pathways of insulin secretion in rat islets cultured for 1 wk in high glucose. | American journal of physiology. Endocrinology and metabolism 20040801 |
| Severe persistent hyperinsulinemic hypoglycemia due to a de novo glucokinase mutation. | Diabetes 20040801 |
| Testosterone modulates K(+)ATP channels in Sertoli cell membrane via the PLC-PIP2 pathway. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20040801 |
| Functional distinctions between the mitochondrial ATP-dependent K+ channel (mitoKATP) and its inward rectifier subunit (mitoKIR). | The Journal of biological chemistry 20040730 |
| Both triggering and amplifying pathways contribute to fuel-induced insulin secretion in the absence of sulfonylurea receptor-1 in pancreatic beta-cells. | The Journal of biological chemistry 20040730 |
| Acute increases in arterial blood pressure do not reduce plasma vasopressin levels stimulated by angiotensin II or hyperosmolality in rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20040701 |
| Growth hormone promotes Ca(2+)-induced Ca2+ release in insulin-secreting cells by ryanodine receptor tyrosine phosphorylation. | Molecular endocrinology (Baltimore, Md.) 20040701 |
| NO donor-activated PKC-delta plays a pivotal role in ischemic myocardial protection through accelerated opening of mitochondrial K-ATP channels. | Journal of cardiovascular pharmacology 20040701 |
| Effect of classic preconditioning and diazoxide on endothelial function and O2- and NO generation in the post-ischemic guinea-pig heart. | Cardiovascular research 20040701 |
| A case of severe diazoxide toxicity. | Paediatric anaesthesia 20040701 |
| The anti-inflammatory effect of diazoxide in coronary artery bypass grafting. | Shock (Augusta, Ga.) 20040701 |
| Glucose- and interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective potassium channel opener in human islets. | Diabetes 20040701 |
| Insulin feedback alters mitochondrial activity through an ATP-sensitive K+ channel-dependent pathway in mouse islets and beta-cells. | Diabetes 20040701 |
| Mutation at position -132 in the islet amyloid polypeptide ( IAPP) gene promoter enhances basal transcriptional activity through a new CRE-like binding site. | Diabetologia 20040701 |
| Preconditioning of the myocardium by volatile anesthetics. | Current medicinal chemistry. Cardiovascular and hematological agents 20040701 |
| The major glucagon-like peptide-1 metabolite, GLP-1-(9-36)-amide, does not affect glucose or insulin levels in mice. | European journal of pharmacology 20040628 |
| Potassium channel openers are uncoupling protonophores: implication in cardioprotection. | FEBS letters 20040618 |
| Palmitate increases L-type Ca2+ currents and the size of the readily releasable granule pool in mouse pancreatic beta-cells. | The Journal of physiology 20040615 |
| Arylcyanoguanidines as activators of Kir6.2/SUR1K ATP channels and inhibitors of insulin release. | Journal of medicinal chemistry 20040603 |
| Regulation by glucose and calcium of the carboxylmethylation of the catalytic subunit of protein phosphatase 2A in insulin-secreting INS-1 cells. | American journal of physiology. Endocrinology and metabolism 20040601 |
| Diazoxide preconditioning protects against neuronal cell death by attenuation of oxidative stress upon glutamate stimulation. | Journal of neuroscience research 20040601 |
| Role of calcium in pancreatic islet cell death by IFN-gamma/TNF-alpha. | Journal of immunology (Baltimore, Md. : 1950) 20040601 |
| Glucose and insulin treatment of insulinoma cells results in transcriptional regulation of a common set of genes. | Diabetes 20040601 |
| Inhibition of insulin secretion as a new drug target in the treatment of metabolic disorders. | Current medicinal chemistry 20040601 |
| Nitric oxide protects rat hepatocytes against reperfusion injury mediated by the mitochondrial permeability transition. | Hepatology (Baltimore, Md.) 20040601 |
| Diazoxide and dimethyl sulphoxide prevent cerebral hypoperfusion-related learning dysfunction and brain damage after carotid artery occlusion. | Brain research 20040522 |
| Diazoxide affects the IF1 inhibitor protein binding to F1 sector of beef heart F0F1ATPsynthase. | Biochemical pharmacology 20040515 |
| Quinine inhibits mitochondrial ATP-regulated potassium channel from bovine heart. | The Journal of membrane biology 20040515 |
| The human mitochondrial KATP channel is modulated by calcium and nitric oxide: a patch-clamp approach. | Biochimica et biophysica acta 20040512 |
| Restitution of defective glucose-stimulated insulin release of sulfonylurea type 1 receptor knockout mice by acetylcholine. | American journal of physiology. Endocrinology and metabolism 20040501 |
| Openers of ATP-dependent K+-channels protect against a signal-transduction-linked and not freely reversible defect of insulin secretion in a rat islet transplantation model of Type 2 diabetes. | Diabetologia 20040501 |
| [The research method for investigating the role of the mitochondrial permeability transition pore in cell death]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20040501 |
| Cardioprotective effects of mitochondrial KATP channels activated at different time. | Chinese medical journal 20040501 |
| Transient mitochondrial permeability transition pore opening mediates preconditioning-induced protection. | Circulation 20040413 |
| Additive antinociceptive effect of the combination of diazoxide, an activator of ATP-sensitive K+ channels, and sodium nitroprusside and dibutyryl-cGMP. | European journal of pharmacology 20040405 |
| Exogenous nitric oxide generates ROS and induces cardioprotection: involvement of PKG, mitochondrial KATP channels, and ERK. | American journal of physiology. Heart and circulatory physiology 20040401 |
| A store-operated mechanism determines the activity of the electrically excitable glucagon-secreting pancreatic alpha-cell. | Cell calcium 20040401 |
| Attenuation of hyperinsulinemia by NN414, a SUR1/Kir6.2 selective K-adenosine triphosphate channel opener, improves glucose tolerance and lipid profile in obese Zucker rats. | Metabolism: clinical and experimental 20040401 |
| [Diagnosis and treatment of insulinoma]. | Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20040401 |
| Sulfonylureas correct trafficking defects of ATP-sensitive potassium channels caused by mutations in the sulfonylurea receptor. | The Journal of biological chemistry 20040319 |
| Chromatographic multivariate quality control of pharmaceuticals giving strongly overlapped peaks based on the chromatogram profile. | Journal of chromatography. A 20040312 |
| Influence of central administration ATP-dependent K+ channel on morphine state-dependent memory of passive avoidance. | European journal of pharmacology 20040308 |
| Evidence for mitochondrial K+ channels and their role in cardioprotection. | Circulation research 20040305 |
| ROS are required for rapid reactivation of Na+/Ca2+ exchanger in hypoxic reoxygenated guinea pig ventricular myocytes. | American journal of physiology. Heart and circulatory physiology 20040301 |
| Diazoxide enhances adipose tissue protein kinase B activation and glucose transporter-4 expression in obese Zucker rats. | Medical science monitor : international medical journal of experimental and clinical research 20040301 |
| ROS-mediated ERK activation in delayed protection from anoxic preconditioning in neonatal rat cardiomyocytes. | Chinese medical journal 20040301 |
| Mechanism of apoptosis induced by diazoxide, a K+ channel opener, in HepG2 human hepatoma cells. | Archives of pharmacal research 20040301 |
| Influence of potassium channel modulators on morphine state-dependent memory of passive avoidance. | Behavioural pharmacology 20040301 |
| Adenosine and a nitric oxide donor enhances cardioprotection by preconditioning with isoflurane through mitochondrial adenosine triphosphate-sensitive K+ channel-dependent and -independent mechanisms. | Anesthesiology 20040301 |
| Cyclooxygenase-2 mediates ischemic, anesthetic, and pharmacologic preconditioning in vivo. | Anesthesiology 20040301 |
| Influence of fasting on the effects of diazoxide in the ischemic-reperfused rat heart. | Journal of physiology and biochemistry 20040301 |
| Y-26763: ATP-sensitive K+ channel activation and the inhibition of insulin release from human pancreatic beta-cells. | European journal of pharmacology 20040220 |
| Diazoxide causes early activation of cardiac sarcolemmal KATP channels during metabolic inhibition by an indirect mechanism. | Cardiovascular research 20040215 |
| Delayed preconditioning of the human myocardium: signal transduction and clinical implications. | Cardiovascular research 20040215 |
| Electro-acupuncture preconditioning abrogates the elevation of c-Fos and c-Jun expression in neonatal hypoxic-ischemic rat brains induced by glibenclamide, an ATP-sensitive potassium channel blocker. | Brain research 20040213 |
| 3-trifluoromethyl-4-nitro-5-arylpyrazoles are novel K(ATP) channel agonists. | Bioorganic & medicinal chemistry letters 20040209 |
| The mitochondrial K(ATP) channel opener BMS-191095 induces neuronal preconditioning. | Neuroreport 20040209 |
| Syntaxin-1A binds the nucleotide-binding folds of sulphonylurea receptor 1 to regulate the KATP channel. | The Journal of biological chemistry 20040206 |
| Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells. | Endocrinology 20040201 |
| Autosomal-dominant hypertension with type E brachydactyly is caused by rearrangement on the short arm of chromosome 12. | Hypertension (Dallas, Tex. : 1979) 20040201 |
| Molecular mechanisms of the inhibitory effects of propofol and thiamylal on sarcolemmal adenosine triphosphate-sensitive potassium channels. | Anesthesiology 20040201 |
| Long-chain CoA esters activate human pancreatic beta-cell KATP channels: potential role in Type 2 diabetes. | Diabetologia 20040201 |
| Difference in the cardioprotective mechanisms between ischemic preconditioning and pharmacological preconditioning by diazoxide in rat hearts. | Circulation journal : official journal of the Japanese Circulation Society 20040201 |
| Roles of mitochondria in health and disease. | Diabetes 20040201 |
| Visualization of the specific interaction of sulfonylurea-incorporated polymer with insulinoma cell line MIN6. | Journal of biochemistry 20040201 |
| Severe transient neonatal hyperinsulinism associated with hyperlactataemia in non-asphyxiated infants. | Journal of pediatric endocrinology & metabolism : JPEM 20040201 |
| [Congenital hyperinsulinism in 15 infants, 1981-1999; experiences and new insights]. | Nederlands tijdschrift voor geneeskunde 20040117 |
| Modulation of the excitability of cholinergic basal forebrain neurones by KATP channels. | The Journal of physiology 20040115 |
| Bradykinin induces mitochondrial ROS generation via NO, cGMP, PKG, and mitoKATP channel opening and leads to cardioprotection. | American journal of physiology. Heart and circulatory physiology 20040101 |
| Distinct roles for insulin and insulin-like growth factor-1 receptors in pancreatic beta-cell glucose sensing revealed by RNA silencing. | The Biochemical journal 20040101 |
| Regulation by sulfanylurea receptor type 1 of a non-selective cation channel involved in cytotoxic edema of reactive astrocytes. | Journal of neurosurgical anesthesiology 20040101 |
| Binding of sulfonylurea by AtMRP5, an Arabidopsis multidrug resistance-related protein that functions in salt tolerance. | Plant physiology 20040101 |
| Activation of mitochondrial ATP-sensitive potassium channels delays ischemia-induced cellular uncoupling in rat heart. | Acta pharmacologica Sinica 20040101 |
| Nine weeks of bedtime diazoxide is well tolerated and improves beta-cell function in subjects with Type 2 diabetes. | Diabetic medicine : a journal of the British Diabetic Association 20040101 |
| Hyperinsulinaemic hypoglycaemia in preterm neonates. | Archives of disease in childhood. Fetal and neonatal edition 20040101 |
| Diazoxide provides protection to human myocardium in vitro that is concentration dependent. | The Annals of thoracic surgery 20040101 |
| Subcellular heterogeneity in mitochondrial red-ox responses to KATP channel agonists in freshly isolated rabbit cardiomyocytes. | Molecular and cellular biochemistry 20040101 |
| Nesidioblastosis treated successfully by 85% pancreatectomy. | The Kurume medical journal 20040101 |
| [Study of the mechanism of action of novel fluoro-containing analogs of diazoxide on the vascular tonus]. | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20040101 |
| [Fluorine-containing analog of diazoxide prevented apoptosis in neonatal cardiomyocytes during anoxia-reoxygenation]. | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20040101 |
| The aminoguanidine carboxylate BVT.12777 activates ATP-sensitive K+ channels in the rat insulinoma cell line, CRI-G1. | BMC pharmacology 20040101 |
| [The effect of K(ATP)-channel activation on the electrical stability of myocardium in rats with postinfarction cardiosclerosis]. | Eksperimental'naia i klinicheskaia farmakologiia 20040101 |
| [Persistent hyperinsulinemic hypoglycemia. Two case reports]. | Cirugia y cirujanos 20040101 |
| Hirsutism: common clinical problem or index of serious disease? | MedGenMed : Medscape general medicine 20040101 |
| Mechanisms of cardioprotective effects of magnesium on hypoxia-reoxygenation-induced injury. | Experimental and clinical cardiology 20040101 |
| Palmitate-induced Ca2+-signaling in pancreatic beta-cells. | Molecular and cellular endocrinology 20031230 |
| Prolonged culture in low glucose induces apoptosis of rat pancreatic beta-cells through induction of c-myc. | Biochemical and biophysical research communications 20031226 |
| Investigation of the subunit composition and the pharmacology of the mitochondrial ATP-dependent K+ channel in the brain. | Brain research 20031219 |
| Mitochondrial ATP-sensitive potassium channels in surgical cardioprotection. | Archives of biochemistry and biophysics 20031215 |
| Effects of the beta-carbolines, harmane and pinoline, on insulin secretion from isolated human islets of Langerhans. | European journal of pharmacology 20031215 |
| ATP-sensitive K+ channels in renal mitochondria. | American journal of physiology. Renal physiology 20031201 |
| Amiodarone inhibits sarcolemmal but not mitochondrial KATP channels in Guinea pig ventricular cells. | The Journal of pharmacology and experimental therapeutics 20031201 |
| The cardioprotective effects of Na+/H+ exchange inhibition and mitochondrial KATP channel activation are additive in the isolated rat heart. | Pflugers Archiv : European journal of physiology 20031201 |
| Novel pharmacological preconditioning with diazoxide attenuates myocardial stunning in coronary artery bypass grafting. | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20031201 |
| Time course of vascular reactivity to contracting and relaxing agents after endothelial denudation by balloon angioplasty in rat carotid artery. | Atherosclerosis 20031201 |
| Trimethoprim-sulfamethoxazole induced prolonged hypoglycemia in an infant with MHC class II deficiency: diazoxide as a treatment option. | Journal of pediatric endocrinology & metabolism : JPEM 20031201 |
| Comparative effects of efaroxan and beta-carbolines on the secretory activity of rodent and human beta cells. | Annals of the New York Academy of Sciences 20031201 |
| Early biochemical and histological alterations in rat corticoencephalic cell cultures following metabolic damage and treatment with modulators of mitochondrial ATP-sensitive potassium channels. | Neurochemistry international 20031101 |
| Interactions of diazoxide with frusemide, spironolactone, and acetylsalicylic acid in a patient with hyperinsulinism of Infancy and Fallot tetralogy. | European journal of pediatrics 20031101 |
| Enhanced cardioprotection of the rat heart during hypothermic storage with combined Na+ - H+ exchange inhibition and ATP-dependent potassium channel activation. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20031101 |
| Heart mitochondria contain functional ATP-dependent K+ channels. | Journal of molecular and cellular cardiology 20031101 |
| Ca2+ influx does not trigger glucose-induced traffic of the insulin granules and alteration of their distribution. | Experimental biology and medicine (Maywood, N.J.) 20031101 |
| Diazoxide induces delayed pre-conditioning in cultured rat cortical neurons. | Journal of neurochemistry 20031101 |
| ATP-dependent K+ channels in renal ischemia reperfusion injury. | Renal failure 20031101 |
| 1,5-Anhydroglucitol stimulates insulin release in insulinoma cell lines. | Biochimica et biophysica acta 20031013 |
| Potent and selective activation of the pancreatic beta-cell type K(ATP) channel by two novel diazoxide analogues. | Diabetologia 20031001 |
| Intracellular mechanism of mitochondrial adenosine triphosphate-sensitive potassium channel activation with isoflurane. | Anesthesia and analgesia 20031001 |
| Isoflurane pretreatment has immediate and delayed protective effects against cytokine-induced injury in endothelial and vascular smooth muscle cells. | Anesthesiology 20031001 |
| Intra-myocyte ion homeostasis during ischemia-reperfusion injury: effects of pharmacologic preconditioning and controlled reperfusion. | The Annals of thoracic surgery 20031001 |
| Early ischemic preconditioning for spinal cord protection. | The Annals of thoracic surgery 20031001 |
| A case of partial trisomy 13 presenting with hyperinsulinaemic hypoglycaemia. | Hong Kong medical journal = Xianggang yi xue za zhi 20031001 |
| HL-1 myocytes exhibit PKC and K(ATP) channel-dependent delta opioid preconditioning. | The Journal of surgical research 20031001 |
| Effectiveness of octreotide in a case of refractory sulfonylurea-induced hypoglycemia. | The Journal of emergency medicine 20031001 |
| ATP-sensitive K+ channel openers: old drugs with new clinical benefits for the heart. | Current vascular pharmacology 20031001 |
| Functional coupling between sulfonylurea receptor type 1 and a nonselective cation channel in reactive astrocytes from adult rat brain. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030917 |
| Both metabolic inhibition and mitochondrial K(ATP) channel opening are myoprotective and initiate a compensatory sarcolemmal outward membrane current. | Circulation 20030909 |
| Combined pharmacological preconditioning with a G-protein-coupled receptor agonist, a mitochondrial KATP channel opener and a nitric oxide donor mimics ischaemic preconditioning. | Clinical and experimental pharmacology & physiology 20030901 |
| Chemical preconditioning prevents paradoxical increase in glutamate release during ischemia by activating ATP-dependent potassium channels in gerbil hippocampus. | Experimental neurology 20030901 |
| ATP-sensitive potassium channels induced in liver cells after transfection with insulin cDNA and the GLUT 2 transporter regulate glucose-stimulated insulin secretion. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030901 |
| The K+ channel openers diazoxide and NS1619 induce depolarization of mitochondria and have differential effects on cell Ca2+ in CD34+ cell line KG-1a. | Experimental hematology 20030901 |
| P1075 opens mitochondrial K(ATP) channels and generates reactive oxygen species resulting in cardioprotection of rabbit hearts. | Journal of molecular and cellular cardiology 20030901 |
| Evidence for rapid 'metabolic switching' through lipoprotein lipase occupation of endothelial-binding sites. | Journal of molecular and cellular cardiology 20030901 |
| Circulating triglyceride lipolysis facilitates lipoprotein lipase translocation from cardiomyocyte to myocardial endothelial lining. | Cardiovascular research 20030901 |
| [Sevoflurane anesthesia for pancreatectomy in an infant with nesidioblastosis]. | Masui. The Japanese journal of anesthesiology 20030901 |
| Protective effects of the potassium channel opener-diazoxide against injury in neonatal rat ventricular myocytes. | General physiology and biophysics 20030901 |
| Cardioprotective effect of diazoxide is mediated by activation of sarcolemmal but not mitochondrial ATP-sensitive potassium channels in mice. | Circulation 20030812 |
| Activation of the KATP channel-independent signaling pathway by the nonhydrolyzable analog of leucine, BCH. | American journal of physiology. Endocrinology and metabolism 20030801 |
| Diazoxide attenuates glucose-induced defects in first-phase insulin release and pulsatile insulin secretion in human islets. | Endocrinology 20030801 |
| N-terminal transmembrane domain of the SUR controls trafficking and gating of Kir6 channel subunits. | The EMBO journal 20030801 |
| K(ATP) channels and pancreatic islet blood flow in anesthetized rats: increased blood flow induced by potassium channel openers. | Diabetes 20030801 |
| Involvement of mitochondrial K+ release and cellular efflux in ischemic and apoptotic neuronal death. | Journal of neurochemistry 20030801 |
| Insulin-like growth factor-1 prevents loss of electrochemical gradient in cardiac muscle mitochondria via activation of PI 3 kinase/Akt pathway. | Molecular and cellular endocrinology 20030731 |
| Degradation of phosphatidylethanol counteracts the apparent phospholipase D-mediated formation in heart and other organs. | Biochimica et biophysica acta 20030721 |
| Toward tissue-selective pancreatic B-cells KATP channel openers belonging to 3-alkylamino-7-halo-4H-1,2,4-benzothiadiazine 1,1-dioxides. | Journal of medicinal chemistry 20030717 |
| Diazoxide pretreatment induces delayed preconditioning in astrocytes against oxygen glucose deprivation and hydrogen peroxide-induced toxicity. | Journal of neuroscience research 20030715 |
| Mitochondrial ATP-sensitive potassium channel activation protects cerebellar granule neurons from apoptosis induced by oxidative stress. | Stroke 20030701 |
| Effects of fatty acids in isolated mitochondria: implications for ischemic injury and cardioprotection. | American journal of physiology. Heart and circulatory physiology 20030701 |
| [125I]A-312110, a novel high-affinity 1,4-dihydropyridine ATP-sensitive K+ channel opener: characterization and pharmacology of binding. | Molecular pharmacology 20030701 |
| Long-term follow-up of 114 patients with congenital hyperinsulinism. | European journal of endocrinology 20030701 |
| Mitochondrial plasticity in classical ischemic preconditioning-moving beyond the mitochondrial KATP channel. | Cardiovascular research 20030701 |
| Ischaemic preconditioning and a mitochondrial KATP channel opener both produce cardioprotection accompanied by F1F0-ATPase inhibition in early ischaemia. | Basic research in cardiology 20030701 |
| Effect of high concentration of glucose on dopamine release from pheochromocytoma-12 cells. | Metabolism: clinical and experimental 20030701 |
| Integrated pharmacological preconditioning in combination with adenosine, a mitochondrial KATP channel opener and a nitric oxide donor. | The Journal of thoracic and cardiovascular surgery 20030701 |
| Ischaemic tolerance in aged mouse myocardium: the role of adenosine and effects of A1 adenosine receptor overexpression. | The Journal of physiology 20030615 |
| ATP-sensitive potassium channels in rat primary afferent neurons: the effect of neuropathic injury and gabapentin. | Neuroscience letters 20030612 |
| Elevated dietary salt suppresses renin secretion but not thirst evoked by arterial hypotension in rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20030601 |
| Diazoxide triggers cardioprotection against apoptosis induced by oxidative stress. | American journal of physiology. Heart and circulatory physiology 20030601 |
| Antiangiogenic effect of KR-31372 by apoptosis via mediation of mitochondrial KATP channel opening and the phosphatase and tensin homolog deleted from chromosome 10 phosphorylation. | The Journal of pharmacology and experimental therapeutics 20030601 |
| Insulin inhibits rat hippocampal neurones via activation of ATP-sensitive K+ and large conductance Ca2+-activated K+ channels. | Neuropharmacology 20030601 |
| Specific and combined effects of insulin and glucose on functional pancreatic beta-cell mass in vivo in adult rats. | Endocrinology 20030601 |
| Mitochondrial ATP-sensitive potassium channel: a novel site for neuroprotection. | Investigative ophthalmology & visual science 20030601 |
| Acetylcholine-induced production of reactive oxygen species in adult rabbit ventricular myocytes is dependent on phosphatidylinositol 3- and Src-kinase activation and mitochondrial K(ATP) channel opening. | Journal of molecular and cellular cardiology 20030601 |
| Functional involvement of sulphonylurea receptor (SUR) type 1 and 2B in the activity of pig urethral ATP-sensitive K+ channels. | British journal of pharmacology 20030601 |
| Adenosine-mediated early preconditioning in mouse: protective signaling and concentration dependent effects. | Cardiovascular research 20030601 |
| Coronary endothelial dysfunction after ischemia and reperfusion and its prevention by ischemic preconditioning. | Italian heart journal : official journal of the Italian Federation of Cardiology 20030601 |
| Differential activation of protein kinase C between ischemic and pharmacological preconditioning in the rabbit heart. | The Japanese journal of physiology 20030601 |
| Surgery of persistent hyperinsulinaemic hypoglycaemia. | Seminars in neonatology : SN 20030601 |
| Mechanisms of delayed electrical uncoupling induced by ischemic preconditioning. | Circulation research 20030530 |
| Activation of peripheral ATP-sensitive K+ channels mediates the antinociceptive effect of Crotalus durissus terrificus snake venom. | European journal of pharmacology 20030523 |
| Glucose regulates EF-2 phosphorylation and protein translation by a protein phosphatase-2A-dependent mechanism in INS-1-derived 832/13 cells. | The Journal of biological chemistry 20030516 |
| Isoflurane activates rat mitochondrial ATP-sensitive K+ channels reconstituted in lipid bilayers. | American journal of physiology. Heart and circulatory physiology 20030501 |
| Contrasting roles of a novel K+ channel blocker and a K+ channel opener on electro-mechanical activity in canine heart tissue. | International journal of cardiology 20030501 |
| Binding and effect of K ATP channel openers in the absence of Mg2+. | British journal of pharmacology 20030501 |
| Cellular uptake of a catechol iron chelator and chloroquine into Plasmodium falciparum infected erythrocytes. | Biochemical pharmacology 20030415 |
| Imidazoline NNC77-0074 stimulates insulin secretion and inhibits glucagon release by control of Ca(2+)-dependent exocytosis in pancreatic alpha- and beta-cells. | European journal of pharmacology 20030411 |
| Hypothalamic proopiomelanocortin neurons are glucose responsive and express K(ATP) channels. | Endocrinology 20030401 |
| Persistent hyperinsulinemic hypoglycaemia followed as benign infantile convulsion. | Seizure 20030401 |
| Insulin does not mediate glucose stimulation of proinsulin biosynthesis. | Diabetes 20030401 |
| Targeting nucleotide-requiring enzymes: implications for diazoxide-induced cardioprotection. | American journal of physiology. Heart and circulatory physiology 20030401 |
| Activation of Akt is essential for acetylcholine to trigger generation of oxygen free radicals. | Cardiovascular research 20030401 |
| Modulation of mitochondrial adenosine triphosphate-sensitive potassium channels and sodium-hydrogen exchange provide additive protection from severe ischemia-reperfusion injury. | The Journal of thoracic and cardiovascular surgery 20030401 |
| Adenine nucleotide translocase mediates the K(ATP)-channel-openers-induced proton and potassium flux to the mitochondrial matrix. | Journal of bioenergetics and biomembranes 20030401 |
| [Changes in cardiac resistance to arrhythmogenic effects during ATP-dependent K+ channel activation]. | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20030401 |
| Synthesis and biological activity of 3,3-diamino-sulfonylacrylonitriles as novel inhibitors of glucose induced insulin secretion from beta cells. | Bioorganic & medicinal chemistry 20030320 |
| Matrix volume measurements challenge the existence of diazoxide/glibencamide-sensitive KATP channels in rat mitochondria. | The Journal of physiology 20030315 |
| MCC-134, a single pharmacophore, opens surface ATP-sensitive potassium channels, blocks mitochondrial ATP-sensitive potassium channels, and suppresses preconditioning. | Circulation 20030304 |
| Mechanism of inhibitory actions of oxidizing agents on calcium-activated potassium current in cultured pigment epithelial cells of the human retina. | Investigative ophthalmology & visual science 20030301 |
| Activation of mitochondrial ATP-sensitive potassium channels increases cell viability against rotenone-induced cell death. | Journal of neurochemistry 20030301 |
| Pharmacological agents that directly modulate insulin secretion. | Pharmacological reviews 20030301 |
| The effects of KATP channel modulators on counterregulatory responses and cognitive function during acute controlled hypoglycaemia in healthy men: a pilot study. | Diabetic medicine : a journal of the British Diabetic Association 20030301 |
| Modulation of the trafficking efficiency and functional properties of ATP-sensitive potassium channels through a single amino acid in the sulfonylurea receptor. | The Journal of biological chemistry 20030227 |
| Cardioprotective effect of diazoxide is mediated by activation of sarcolemmal but not mitochondrial ATP-sensitive potassium channels in mice. | Circulation 20030211 |
| Differential actions of cardioprotective agents on the mitochondrial death pathway. | Circulation research 20030207 |
| Receptor and non-receptor-dependent mechanisms of cardioprotection with adenosine. | American journal of physiology. Heart and circulatory physiology 20030201 |
| Inhibition of vascular ATP-sensitive K+ channels does not affect reactive hyperemia in human forearm. | American journal of physiology. Heart and circulatory physiology 20030201 |
| Differential sensitivity of atrial and ventricular K(ATP) channels to metabolic inhibition. | Cardiovascular research 20030201 |
| Differential effects of sulphonylureas on the vasodilatory response evoked by K(ATP) channel openers. | Fundamental & clinical pharmacology 20030201 |
| The mitochondrial K(ATP) channel and cardioprotection. | The Annals of thoracic surgery 20030201 |
| Characterisation of new KATP-channel mutations associated with congenital hyperinsulinism in the Finnish population. | Diabetologia 20030201 |
| Prolonged hyperinsulinemic hypoglycemia in a small for date preterm. | Minerva pediatrica 20030201 |
| Leptin fully suppresses acetylcholine-induced insulin secretion and is reversed by tolbutamide in isolated perfused chicken pancreas. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20030201 |
| Glucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cells. | The Biochemical journal 20030115 |
| Ischemic preconditioning in the hippocampus of a knockout mouse lacking SUR1-based K(ATP) channels. | Stroke 20030101 |
| Increased vulnerability to ischemia/reperfusion-induced ventricular tachyarrhythmias by pre-ischemic inhibition of nitric oxide synthase in isolated rat hearts. | Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 20030101 |
| Involvement of mitogen-activated protein kinases and reactive oxygen species in the inotropic action of ouabain on cardiac myocytes. A potential role for mitochondrial K(ATP) channels. | Molecular and cellular biochemistry 20030101 |
| Effects of sulfonylureas on K(ATP) channel-dependent vasodilation. | Journal of diabetes and its complications 20030101 |
| Protection of rat pancreatic islets by potassium channel openers against alloxan, sodium nitroprusside and interleukin-1beta mediated suppression--possible involvement of the mitochondrial membrane potential. | Diabetologia 20030101 |
| [Malignant insulinoma in an 84-year-old woman]. | Anales de medicina interna (Madrid, Spain : 1984) 20030101 |
| [Treatment of insulinoma with diazoxide]. | Medicina 20030101 |
| Ischemic and pharmacological induction of delayed cellular protection in iNOS gene-disrupted mice myocytes. | Polish journal of pharmacology 20030101 |
| Role of mitochondrial KATP channels and protein kinase C in ischaemic preconditioning. | Clinical and experimental pharmacology & physiology 20030101 |
| Gender differences in effects of pinacidil but not diazoxide on heart automatism in the isolated guinea pig right atria. | Polish journal of pharmacology 20030101 |
| Persistent hyperinsulinemic neonatal hypoglycemia caused by focal nesidioblastosis. Preoperative diagnosis by pancreatic venous sampling. | Hormones (Athens, Greece) 20030101 |
| Methyl pyruvate stimulates pancreatic beta-cells by a direct effect on KATP channels, and not as a mitochondrial substrate. | The Biochemical journal 20021215 |
| The effects of ischaemic preconditioning, diazoxide and 5-hydroxydecanoate on rat heart mitochondrial volume and respiration. | The Journal of physiology 20021215 |
| Opening of potassium channels modulates mitochondrial function in rat skeletal muscle. | Biochimica et biophysica acta 20021202 |
| Expression and activity of potassium ion channels in human prostate cancer. | Cancer letters 20021201 |
| Mitochondrial Ca2+ uptake is important over low [Ca2+]i range in arterial smooth muscle. | American journal of physiology. Heart and circulatory physiology 20021201 |
| The role of mitochondrial K(ATP) channels in the antiarrhythmic effects of ischaemic preconditioning in dogs. | British journal of pharmacology 20021201 |
| The role of mitochondrial K(ATP) channels in antiarrhythmic effects of ischaemic preconditioning in dogs. | British journal of pharmacology 20021201 |
| Serum inhibin B in polycystic ovary syndrome: regulation by insulin and luteinizing hormone. | The Journal of clinical endocrinology and metabolism 20021201 |
| Diazoxide in the treatment of schizophrenia: novel application of potassium channel openers in the treatment of schizophrenia. | Journal of clinical pharmacy and therapeutics 20021201 |
| Rapid insulin assay for intraoperative confirmation of complete resection of insulinomas. | Surgery 20021201 |
| Improved beta cell function after short-term treatment with diazoxide in obese subjects with type 2 diabetes. | Diabetes & metabolism 20021201 |
| Uncontrolled insulin secretion from a childhood pancreatic beta-cell adenoma is not due to the functional loss of ATP-sensitive potassium channels. | Endocrine-related cancer 20021201 |
| Diazoxide amelioration of myocardial injury and mitochondrial damage during cardiac surgery. | The Annals of thoracic surgery 20021201 |
| Inhibition of Kv2.1 voltage-dependent K+ channels in pancreatic beta-cells enhances glucose-dependent insulin secretion. | The Journal of biological chemistry 20021122 |
| The cytoplasmic C-terminus of the sulfonylurea receptor is important for KATP channel function but is not key for complex assembly or trafficking. | European journal of biochemistry 20021101 |
| Nicorandil and leukocyte activation. | Journal of cardiovascular pharmacology 20021101 |
| BPDZ 154 activates adenosine 5'-triphosphate-sensitive potassium channels: in vitro studies using rodent insulin-secreting cells and islets isolated from patients with hyperinsulinism. | The Journal of clinical endocrinology and metabolism 20021101 |
| 2-alkyl-3-Alkylamino-2H-Benzo- and pyridothiadiazine 1,1-dioxides: from K+ATP channel openers to Ca++ channel blockers? | Biological chemistry 20021101 |
| Time and amplitude regulation of pulsatile insulin secretion by triggering and amplifying pathways in mouse islets. | FEBS letters 20021023 |
| Synthesis and evaluation of 7-substituted-3-cyclobutylamino-4H-1,2,4-benzothiadiazine-1,1-dioxide derivatives as K(ATP) channel agonists. | Bioorganic & medicinal chemistry letters 20021021 |
| Rescue of beta-cell exhaustion by diazoxide after the development of diabetes mellitus in rats with streptozotocin-induced diabetes. | European journal of pharmacology 20021018 |
| Dynamics of glucose-induced membrane recruitment of protein kinase C beta II in living pancreatic islet beta-cells. | The Journal of biological chemistry 20021004 |
| Cardioprotection by multiple preconditioning cycles does not require mitochondrial K(ATP) channels in pigs. | American journal of physiology. Heart and circulatory physiology 20021001 |
| Long-term administration of nicorandil abolishes ischemic and pharmacologic preconditioning of the human myocardium: role of mitochondrial adenosine triphosphate-dependent potassium channels. | The Journal of thoracic and cardiovascular surgery 20021001 |
| Different regulated expression of the tyrosine phosphatase-like proteins IA-2 and phogrin by glucose and insulin in pancreatic islets: relationship to development of insulin secretory responses in early life. | Diabetes 20021001 |
| Cell-type specific depression of neuronal excitability in rat hippocampus by activation of ATP-sensitive potassium channels. | European biophysics journal : EBJ 20021001 |
| Study of a glucose-activated anion-selective channel in rat pancreatic beta-cells. | Pflugers Archiv : European journal of physiology 20021001 |
| [PHHI (persistent hyperinsulinemic hypoglycemia of infancy)]. | Nihon rinsho. Japanese journal of clinical medicine 20021001 |
| Rapid effect of testosterone on rat Sertoli cell membrane potential. Relationship with K+ATP channels. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20021001 |
| Persistent hyperinsulinaemic hypoglycaemia of infancy: case report. | East African medical journal 20021001 |
| 6-Chloro-3-alkylamino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxide derivatives potently and selectively activate ATP sensitive potassium channels of pancreatic beta-cells. | Journal of medicinal chemistry 20020912 |
| The elevation of glutamate content and the amplification of insulin secretion in glucose-stimulated pancreatic islets are not causally related. | The Journal of biological chemistry 20020906 |
| MitoK(ATP) opener, diazoxide, reduces neuronal damage after middle cerebral artery occlusion in the rat. | American journal of physiology. Heart and circulatory physiology 20020901 |
| Glucose-sensing in glucagon-like peptide-1-secreting cells. | Diabetes 20020901 |
| Opening of ATP-sensitive potassium channels causes generation of free radicals in vascular smooth muscle cells. | Basic research in cardiology 20020901 |
| Delta opioid agonists and volatile anesthetics facilitate cardioprotection via potentiation of K(ATP) channel opening. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020901 |
| Pharmacological preconditioning ameliorates neurological injury in a model of spinal cord ischemia. | The Annals of thoracic surgery 20020901 |
| Inhibiting mitochondrial permeability transition pore opening: a new paradigm for myocardial preconditioning? | Cardiovascular research 20020815 |
| Acetylcholine leads to free radical production dependent on K(ATP) channels, G(i) proteins, phosphatidylinositol 3-kinase and tyrosine kinase. | Cardiovascular research 20020815 |
| Classic ischemic but not pharmacologic preconditioning is abrogated following genetic ablation of the TNFalpha gene. | Cardiovascular research 20020815 |
| Effects of mitochondrial K(ATP) modulators on cardioprotection induced by chronic high altitude hypoxia in rats. | Cardiovascular research 20020815 |
| Ischemic preconditioning protection against stunning in conscious diabetic sheep: role of glucose, insulin, sarcolemmal and mitochondrial KATP channels. | Cardiovascular research 20020815 |
| The relative order of mK(ATP) channels, free radicals and p38 MAPK in preconditioning's protective pathway in rat heart. | Cardiovascular research 20020815 |
| Glucose lowering effect of aqueous extract of Enicostemma littorale Blume in diabetes: a possible mechanism of action. | Journal of ethnopharmacology 20020801 |
| Neonatal hyperinsulinemic hypoglycemia. Two case reports. | Minerva pediatrica 20020801 |
| Evidence that the novel imidazoline compound FT005 is an alpha(2)-adrenoceptor agonist. | British journal of pharmacology 20020801 |
| Sulfatide controls insulin secretion by modulation of ATP-sensitive K(+)-channel activity and Ca(2+)-dependent exocytosis in rat pancreatic beta-cells. | Diabetes 20020801 |
| K(ATP) channel-independent targets of diazoxide and 5-hydroxydecanoate in the heart. | The Journal of physiology 20020801 |
| Diazoxide for cerebral protection during deep hypothermic circulatory arrest: is it really safe? | The Annals of thoracic surgery 20020801 |
| Pancreatectomy extension in persistent hyperinsulinaemic hypoglycaemia: a new strategy. | European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie 20020801 |
| Opening of mitochondrial K+ channels increases ischemic ATP levels by preventing hydrolysis. | Journal of bioenergetics and biomembranes 20020801 |
| Persistent hyperinsulinemic hypoglycemia of infancy: experience at Siriraj Hospital. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20020801 |
| Glucagon is paradoxically secreted at high concentrations of glucose in rat pancreas perfused with diazoxide. | Diabetes, nutrition & metabolism 20020801 |
| The role of myocardial KATP-channel blockade in the protective effects of glibenclamide against ischaemia in the rat heart. | Pharmacology & toxicology 20020801 |
| Activation of mitochondrial ATP-sensitive potassium channels prevents neuronal cell death after ischemia in neonatal rats. | Neuroscience letters 20020726 |
| Mitochondrial K(ATP) channel openers activate the ERK kinase by an oxidant-dependent mechanism. | American journal of physiology. Cell physiology 20020701 |
| Role of nitric oxide synthase isoforms in glucose-stimulated insulin release. | American journal of physiology. Cell physiology 20020701 |
| Ketamine abolishes ischemic preconditioning through inhibition of K(ATP) channels in rabbit hearts. | American journal of physiology. Heart and circulatory physiology 20020701 |
| Mechanisms by which opening the mitochondrial ATP- sensitive K(+) channel protects the ischemic heart. | American journal of physiology. Heart and circulatory physiology 20020701 |
| Opening of mitochondrial K(ATP) channel occurs downstream of PKC-epsilon activation in the mechanism of preconditioning. | American journal of physiology. Heart and circulatory physiology 20020701 |
| Effect of metabolic inhibition on glimepiride block of native and cloned cardiac sarcolemmal K(ATP) channels. | British journal of pharmacology 20020701 |
| Suppression of human tumor cell proliferation through mitochondrial targeting. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020701 |
| Volatile anesthetics mimic cardiac preconditioning by priming the activation of mitochondrial K(ATP) channels via multiple signaling pathways. | Anesthesiology 20020701 |
| Differential effects of anesthetics on mitochondrial K(ATP) channel activity and cardiomyocyte protection. | Anesthesiology 20020701 |
| Effect of pretreatment with adenosine, diazoxide or ischemic preconditioning on ischemia- reperfusion injury in the limbs of rats. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20020701 |
| Oral hypoglycemic sulfonylurea glimepiride preserves the myoprotective effects of ischemic preconditioning. | The Journal of surgical research 20020615 |
| Diazoxide opens the mitochondrial permeability transition pore and alters Ca2+ transients in rat ventricular myocytes. | Circulation 20020604 |
| The novel diazoxide analog 3-isopropylamino-7-methoxy-4H-1,2,4-benzothiadiazine 1,1-dioxide is a selective Kir6.2/SUR1 channel opener. | Diabetes 20020601 |
| Chronic suppression of insulin by diazoxide alters the activities of key enzymes regulating hepatic gluconeogenesis in Zucker rats. | European journal of endocrinology 20020601 |
| Clinically relevant concentrations of propofol have no effect on adenosine triphosphate-sensitive potassium channels in rat ventricular myocytes. | Anesthesiology 20020601 |
| Modulation of a plant mitochondrial K+ATP channel and its involvement in cytochrome c release. | Journal of bioenergetics and biomembranes 20020601 |
| Identification of a familial hyperinsulinism-causing mutation in the sulfonylurea receptor 1 that prevents normal trafficking and function of KATP channels. | The Journal of biological chemistry 20020510 |
| Troglitazone ameliorates lipotoxicity in the beta cell line INS-1 expressing PPAR gamma. | Diabetes research and clinical practice 20020501 |
| High-performance liquid chromatographic method with ultraviolet detection for the determination of dapsone and its hydroxylated metabolite in human plasma. | Biomedical chromatography : BMC 20020501 |
| Contribution of the endoplasmic reticulum to the glucose-induced [Ca(2+)](c) response in mouse pancreatic islets. | American journal of physiology. Endocrinology and metabolism 20020501 |
| Mitochondrial ATP-sensitive K+ channels influence force development and anoxic contractility in a flatfish, yellowtail flounder Limanda ferruginea, but not Atlantic cod Gadus morhua heart. | The Journal of experimental biology 20020501 |
| Effects of K(ATP) channel modulators on acetylcholine release from guinea-pig isolated atria and small intestine. | Naunyn-Schmiedeberg's archives of pharmacology 20020501 |
| Cardiomyocyte resistance to doxorubicin mediated by A(3) adenosine receptor. | Journal of molecular and cellular cardiology 20020501 |
| [Hirsutism and hypertrichosis in adults: investigations and treatment]. | Annales de dermatologie et de venereologie 20020501 |
| Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
| Alterations of purine and pyrimidine nucleotide contents in rat corticoencephalic cell cultures following metabolic damage and treatment with openers and blockers of ATP-sensitive potassium channels. | Neurochemistry international 20020401 |
| Correlation between GABA release from rat islet beta-cells and their metabolic state. | American journal of physiology. Endocrinology and metabolism 20020401 |
| Preconditioning blocks cardiocyte apoptosis: role of K(ATP) channels and PKC-epsilon. | American journal of physiology. Heart and circulatory physiology 20020401 |
| Glucosamine-induced beta-cell dysfunction: a possible involvement of glucokinase or glucose-transporter type 2. | Pancreas 20020401 |
| The second activating glucokinase mutation (A456V): implications for glucose homeostasis and diabetes therapy. | Diabetes 20020401 |
| Activation of mitochondrial ATP-dependent potassium channels protects neurons against ischemia-induced death by a mechanism involving suppression of Bax translocation and cytochrome c release. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020401 |
| Effect of ischemic preconditioning and mitochondrial KATP channel openers on chronic left ventricular remodeling in the ischemic-reperfused rat heart. | Circulation journal : official journal of the Japanese Circulation Society 20020401 |
| Radio-frequency ablation for symptom control in a patient with metastatic pancreatic insulinoma. | Clinical endocrinology 20020401 |
| Functional roles of KATP channels in vascular smooth muscle. | Clinical and experimental pharmacology & physiology 20020401 |
| Effects of K(ATP) channel openers, P-1075, pinacidil, and diazoxide, on energetics and contractile function in isolated rat hearts. | Journal of molecular and cellular cardiology 20020401 |
| Compound heterozygosity for the common sulfonylurea receptor mutations can cause mild diazoxide-sensitive hyperinsulinism. | Clinical pediatrics 20020401 |
| The reactivity of serotonin, acetylcholine and kcl-induced contractions to relaxant agents in the rat gastric fundus. | Pharmacological research 20020401 |
| Diazoxide protects the rabbit heart following cardioplegic ischemia. | Molecular and cellular biochemistry 20020401 |
| ATP-dependent potassium channel mediates neuroprotection by chemical preconditioning with 3-nitropropionic acid in gerbil hippocampus. | Neuroscience letters 20020301 |
| Vascular K(ATP) channel blockade by glibenclamide, but not by acarbose, in patients with Type II diabetes. | Clinical science (London, England : 1979) 20020301 |
| Determination of the specific interaction between sulfonylurea-incorporated polymer and rat islets. | Journal of biochemistry 20020301 |
| Selective opening of mitochondrial ATP-sensitive potassium channels during surgically induced myocardial ischemia decreases necrosis and apoptosis. | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20020301 |
| AMPA-induced Ca(2+) influx in cultured rat cortical nonpyramidal neurones: pharmacological characterization using fura-2 microfluorimetry. | European journal of pharmacology 20020301 |
| Membrane potential dependent modulations of calcium oscillations in insulin-secreting INS-1 cells. | Cell calcium 20020301 |
| Potassium channel openers protect cardiac mitochondria by attenuating oxidant stress at reoxygenation. | American journal of physiology. Heart and circulatory physiology 20020201 |
| Overexpression of the Na/Ca exchanger shapes stimulus-induced cytosolic Ca(2+) oscillations in insulin-producing BRIN-BD11 cells. | Diabetes 20020201 |
| Triggering of insulin release by a combination of cAMP signal and nutrients: an ATP-sensitive K+ channel-independent phenomenon. | Diabetes 20020201 |
| The effects of cerulenin, an inhibitor of protein acylation, on the two phases of glucose-stimulated insulin secretion. | Diabetes 20020201 |
| Diazoxide and pinacidil uncouple pyruvate-malate-induced mitochondrial respiration. | Journal of bioenergetics and biomembranes 20020201 |
| Vascular effects of glibenclamide vs. glimepiride and metformin in Type 2 diabetic patients. | Diabetic medicine : a journal of the British Diabetic Association 20020201 |
| Persistent hyperinsulinaemic hypoglycaemia. | Seminars in neonatology : SN 20020201 |
| ATP-sensitive K(+) channels composed of Kir6.1 and SUR2B subunits in guinea pig gastric myocytes. | American journal of physiology. Gastrointestinal and liver physiology 20020101 |
| Phosphatidylinositol 3-kinase suppresses glucose-stimulated insulin secretion by affecting post-cytosolic [Ca(2+)] elevation signals. | Diabetes 20020101 |
| ATP-independent anoxic activation of ATP-sensitive K+ channels in dorsal vagal neurons of juvenile mice in situ. | Neuroscience 20020101 |
| Heterogeneity of persistent hyperinsulinaemic hypoglycaemia. A series of 175 cases. | European journal of pediatrics 20020101 |
| Anaesthetic management of a case of nesidioblastosis for subtotal pancreatectomy. | Paediatric anaesthesia 20020101 |
| Pharmacological and ischemic preconditioning of the human myocardium: mitoK(ATP) channels are upstream and p38MAPK is downstream of PKC. | BMC physiology 20020101 |
| Voltage-gated potassium ion channels in colon cancer. | Oncology reports 20020101 |
| ABCC8 (SUR1) and KCNJ11 (KIR6.2) mutations in persistent hyperinsulinemic hypoglycemia of infancy and evaluation of different therapeutic measures. | Journal of pediatric endocrinology & metabolism : JPEM 20020101 |
| Study of the insulinotropic effect of the novel antihyperglycemic agent KAD-1229 using HIT T15 cells, a hamster's insulinoma cell line. | Arzneimittel-Forschung 20020101 |
| Drugs for treatment of very high blood pressure during pregnancy. | The Cochrane database of systematic reviews 20020101 |
| On the effect of diazoxide on isolated mitochondria from rat myocardium. | Doklady. Biochemistry and biophysics 20020101 |
| Desensitization of insulin secretory response to imidazolines, tolbutamide, and quinine. II. Electrophysiological and fluorimetric studies. | Biochemical pharmacology 20011215 |
| Characteristics and superoxide-induced activation of reconstituted myocardial mitochondrial ATP-sensitive potassium channels. | Circulation research 20011207 |
| Anesthetic effects on mitochondrial ATP-sensitive K channel. | Anesthesiology 20011201 |
| Pharmacologically induced preconditioning with diazoxide: a novel approach to brain protection. | The Annals of thoracic surgery 20011201 |
| Insulin release and suppression by tacrolimus, rapamycin and cyclosporin A are through regulation of the ATP-sensitive potassium channel. | Diabetes, obesity & metabolism 20011201 |
| Hyperinsulinaemic hypoglycaemia--leading symptom in a patient with congenital disorder of glycosylation Ia (phosphomannomutase deficiency). | Journal of inherited metabolic disease 20011201 |
| Opening of mitochondrial K(ATP) channels attenuates the ouabain-induced calcium overload in mitochondria. | Circulation research 20011109 |
| Mitochondrial ATP-sensitive potassium channels attenuate matrix Ca(2+) overload during simulated ischemia and reperfusion: possible mechanism of cardioprotection. | Circulation research 20011109 |
| Management of hyperinsulinemia with diazoxide in an elderly hemodialysis patient. | Nephron 20011101 |
| Mitochondrial K(ATP) channel as an end effector of cardioprotection during late preconditioning: triggering role of nitric oxide. | Journal of molecular and cellular cardiology 20011101 |
| The potential antidiabetic activity of some alpha-2 adrenoceptor antagonists. | Pharmacological research 20011101 |
| Mitochondrial ATP-sensitive channel opener does not induce vascular preconditioning, but potentiates the effect of a preconditioning ischemia on coronary reactive hyperemia in the anesthetized goat. | Pflugers Archiv : European journal of physiology 20011101 |
| Ischemic and pharmacological preconditioning in Girardi cells and C2C12 myotubes induce mitochondrial uncoupling. | Circulation research 20011026 |
| Contribution to glucose tolerance of insulin-independent vs. insulin-dependent mechanisms in mice. | American journal of physiology. Endocrinology and metabolism 20011001 |
| Effect of aging on the ability of preconditioning to protect rat hearts from ischemia-reperfusion injury. | American journal of physiology. Heart and circulatory physiology 20011001 |
| Glucose effects on gastric motility and tone evoked from the rat dorsal vagal complex. | The Journal of physiology 20011001 |
| The KATP channel opener diazoxide protects cardiac myocytes during metabolic inhibition without causing mitochondrial depolarization or flavoprotein oxidation. | British journal of pharmacology 20011001 |
| [Properties of KATP channels in hippocampal CA1 pyramidal neurons from adult rats]. | Sheng li xue bao : [Acta physiologica Sinica] 20011001 |
| Ten years' experience of persistent hyperinsulinaemic hypoglycaemia of infancy. | Journal of paediatrics and child health 20011001 |
| Identification and pharmacological correction of a membrane trafficking defect associated with a mutation in the sulfonylurea receptor causing familial hyperinsulinism. | The Journal of biological chemistry 20010921 |
| Identification and properties of a novel intracellular (mitochondrial) ATP-sensitive potassium channel in brain. | The Journal of biological chemistry 20010907 |
| Amino acids and insulin are both required to regulate assembly of the eIF4E. eIF4G complex in rat skeletal muscle. | American journal of physiology. Endocrinology and metabolism 20010901 |
| Mitochondrial K(ATP) channel activation reduces anoxic injury by restoring mitochondrial membrane potential. | American journal of physiology. Heart and circulatory physiology 20010901 |
| Hepatothermic therapy of obesity: rationale and an inventory of resources. | Medical hypotheses 20010901 |
| Hyperinsulinism and hyperammonemia syndrome: report of twelve unrelated patients. | Pediatric research 20010901 |
| Contribution of both the sarcolemmal K(ATP) and mitochondrial K(ATP) channels to infarct size limitation by K(ATP) channel openers: differences from preconditioning in the role of sarcolemmal K(ATP) channels. | Naunyn-Schmiedeberg's archives of pharmacology 20010901 |
| Diazoxide induced cardioprotection: what comes first, K(ATP) channels or reactive oxygen species? | Cardiovascular research 20010901 |
| Mitochondrial K(ATP) channel opening protects a human atrial-derived cell line by a mechanism involving free radical generation. | Cardiovascular research 20010901 |
| Synthesis and characterization of a quinolinonic compound activating ATP-sensitive K(+) channels in endocrine and smooth muscle tissues. | British journal of pharmacology 20010901 |
| Lidocaine and mexiletine inhibit mitochondrial oxidation in rat ventricular myocytes. | Anesthesiology 20010901 |
| [Activation of ATP-sensitive K+ channels by ADP and K+ channel openers: homology model of sulfonylurea receptor carboxyl-termini]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20010901 |
| Critical timing of mitochondrial K(ATP) channel opening for enhancement of myocardial tolerance against infarction. | Basic research in cardiology 20010901 |
| Incorporation of sulfonylurea into N-isopropylacrylamide as an extracellular matrix for an artificial pancreas. | Bioscience, biotechnology, and biochemistry 20010901 |
| Effects of bezafibrate on beta-cell function of rat pancreatic islets. | European journal of pharmacology 20010831 |
| Modulation of islet ATP content by inhibition or stimulation of the Na(+)/K(+) pump. | European journal of pharmacology 20010824 |
| Original 2-alkylamino-6-halogenoquinazolin-4(3H)-ones and K(ATP) channel activity. | Journal of medicinal chemistry 20010802 |
| Laparoscopic pancreatectomy for persistent hyperinsulinemic hypoglycemia of infancy. | Surgical endoscopy 20010801 |
| ATP-sensitive K+ channels and cellular actions of morphine in periaqueductal gray slices of neonatal and adult rats. | The Journal of pharmacology and experimental therapeutics 20010801 |
| Hyperinsulinism in short-chain L-3-hydroxyacyl-CoA dehydrogenase deficiency reveals the importance of beta-oxidation in insulin secretion. | The Journal of clinical investigation 20010801 |
| Acute insulin responses to leucine in children with the hyperinsulinism/hyperammonemia syndrome. | The Journal of clinical endocrinology and metabolism 20010801 |
| Sulfonylurea receptors inhibit the epithelial sodium channel (ENaC) by reducing surface expression. | Pflugers Archiv : European journal of physiology 20010801 |
| Inhibition of large-conductance calcium-activated potassium channel by 2-methoxyestradiol in cultured vascular endothelial (HUV-EC-C) cells. | The Journal of membrane biology 20010801 |
| Increased calcium vulnerability of senescent cardiac mitochondria: protective role for a mitochondrial potassium channel opener. | Mechanisms of ageing and development 20010731 |
| Phenylcyanoguanidines as inhibitors of glucose-induced insulin secretion from beta cells. | Bioorganic & medicinal chemistry letters 20010709 |
| Downregulation of protein kinase C inhibits activation of mitochondrial K(ATP) channels by diazoxide. | Circulation 20010703 |
| Distinct effect of diazoxide on insulin secretion stimulated by protein kinase A and protein kinase C in rat pancreatic islets. | Diabetes research and clinical practice 20010701 |
| Oral agents for the treatment of type 2 diabetes mellitus: pharmacology, toxicity, and treatment. | Annals of emergency medicine 20010701 |
| Intrinsic optical signals in respiratory brain stem regions of mice: neurotransmitters, neuromodulators, and metabolic stress. | Journal of neurophysiology 20010701 |
| Effect on insulin release of compounds structurally related to the potassium-channel opener 7-chloro-3-isopropylamino-4H-1,2,4-benzothiadiazine 1,1-dioxide (BPDZ 73): introduction of heteroatoms on the 3-alkylamino side chain of the benzothiadiazine 1,1-dioxide ring. | The Journal of pharmacy and pharmacology 20010701 |
| Glimepiride, a novel sulfonylurea, does not abolish myocardial protection afforded by either ischemic preconditioning or diazoxide. | Circulation 20010626 |
| Mitochondrial ATP-sensitive potassium channels inhibit apoptosis induced by oxidative stress in cardiac cells. | Circulation research 20010622 |
| Role of intracellular Na(+) kinetics in preconditioned rat heart. | Circulation research 20010608 |
| A novel enhancer of insulinotrophic action by high glucose (JTT-608) stimulates insulin secretion from pancreatic beta-cells via a new cellular mechanism. | The Journal of pharmacology and experimental therapeutics 20010601 |
| Glucose-regulated pulsatile insulin release from mouse islets via the K(ATP) channel-independent pathway. | European journal of endocrinology 20010601 |
| Diazoxide effects on hypothalamic and extra-hypothalamic NPY content in Zucker rats. | Peptides 20010601 |
| Transient hyperinsulinism in an asphyxiated newborn infant with hypoglycemia. | American journal of perinatology 20010601 |
| Store-operated influx of Ca(2+) in pancreatic beta-cells exhibits graded dependence on the filling of the endoplasmic reticulum. | Journal of cell science 20010601 |
| When it is more than transient neonatal hypoglycemia: hyperinsulinemia--a case study challenge. | Neonatal network : NN 20010601 |
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| Preconditioning limits mitochondrial Ca(2+) during ischemia in rat hearts: role of K(ATP) channels. | American journal of physiology. Heart and circulatory physiology 20010501 |
| Increased intracellular calcium is required for spreading of rat islet beta-cells on extracellular matrix. | Diabetes 20010501 |
| Chloride channels regulate HIT cell volume but cannot fully account for swelling-induced insulin secretion. | Diabetes 20010501 |
| The role of cyclic AMP in the pathogenesis of glucose desensitization in rat pancreatic islets. | Pancreas 20010501 |
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| Glucose and insulin stimulate heparin-releasable lipoprotein lipase activity in mouse islets and INS-1 cells. A potential link between insulin resistance and beta-cell dysfunction. | The Journal of biological chemistry 20010413 |
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| Opening of mitochondrial ATP-sensitive potassium channels enhances cardioplegic protection. | The Annals of thoracic surgery 20010401 |
| Interaction of sulfonylurea-conjugated polymer with insulinoma cell line of MIN6 and its effect on insulin secretion. | Journal of biomedical materials research 20010401 |
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| Functional roles of cardiac and vascular ATP-sensitive potassium channels clarified by Kir6.2-knockout mice. | Circulation research 20010330 |
| Overexpression of a modified human malonyl-CoA decarboxylase blocks the glucose-induced increase in malonyl-CoA level but has no impact on insulin secretion in INS-1-derived (832/13) beta-cells. | The Journal of biological chemistry 20010302 |
| Methyl pyruvate initiates membrane depolarization and insulin release by metabolic factors other than ATP. | The Biochemical journal 20010301 |
| Oxytocin antagonist disrupts hypotension-evoked renin secretion and other responses in conscious rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20010301 |
| Pituitary adenylate cyclase-activating polypeptide activates K(ATP) current in rat atrial myocytes. | American journal of physiology. Heart and circulatory physiology 20010301 |
| Neurologic outcomes of 90 neonates and infants with persistent hyperinsulinemic hypoglycemia. | Pediatrics 20010301 |
| Continuous infusion of glucagon induces severe hyponatremia and thrombocytopenia in a premature neonate. | Pediatrics 20010301 |
| Characterization of secretory and morphologic properties of primary cultured endocrine cells from porcine pancreata. | Pancreas 20010301 |
| Diazoxide, a K(ATP) opener, accelerates restitution of ethanol or indomethacin-induced gastric ulceration in rats independent of polyamines. | Journal of gastroenterology and hepatology 20010301 |
| Failure to precondition pathological human myocardium. | Journal of the American College of Cardiology 20010301 |
| Mitochondrial ATP-sensitive K+ channels play a role in cardioprotection by Na+-H+ exchange inhibition against ischemia/reperfusion injury. | Journal of the American College of Cardiology 20010301 |
| Potassium channel openers depolarize hippocampal mitochondria. | Brain research 20010216 |
| Involvement of K(ATP) channels in diethylstilbestrol-induced relaxation in rat aorta. | European journal of pharmacology 20010209 |
| Bioenergetic consequences of opening the ATP-sensitive K(+) channel of heart mitochondria. | American journal of physiology. Heart and circulatory physiology 20010201 |
| Pharmacological comparison of native mitochondrial K(ATP) channels with molecularly defined surface K(ATP) channels. | Molecular pharmacology 20010201 |
| Diazoxide protects mitochondria from anoxic injury: implications for myopreservation. | The Journal of thoracic and cardiovascular surgery 20010201 |
| [Cardioprotective mechanism of ischemic preconditioning is impaired by postinfarct ventricular remodeling through angiotensin II type 1 receptor activation]. | Journal of cardiology 20010201 |
| Effects of glucose and amino acids on free ADP in betaHC9 insulin-secreting cells. | Diabetes 20010201 |
| Defective stimulus-secretion coupling in islets of Psammomys obesus, an animal model for type 2 diabetes. | Diabetes 20010201 |
| Hyperinsulinism of infancy: the regulated release of insulin by KATP channel-independent pathways. | Diabetes 20010201 |
| Characterization of a KATP channel-independent pathway involved in potentiation of insulin secretion by efaroxan. | Diabetes 20010201 |
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| Downregulation of the voltage-dependent calcium channel (VDCC) beta-subunit mRNAs in pancreatic islets of type 2 diabetic rats. | Biochemical and biophysical research communications 20010126 |
| K(ATP) channel blockers selectively interact with A(1)-adenosine receptor mediated modulation of acetylcholine release in the rat hippocampus. | Brain research 20010119 |
| Phentolamine inhibits exocytosis of glucagon by Gi2 protein-dependent activation of calcineurin in rat pancreatic alpha -cells. | The Journal of biological chemistry 20010112 |
| Direct activation of mitochondrial K(ATP) channels mimics preconditioning but protein kinase C activation is less effective in middle-aged rat hearts. | Cardiovascular research 20010101 |
| Dual roles of mitochondrial K(ATP) channels in diazoxide-mediated protection in isolated rabbit hearts. | American journal of physiology. Heart and circulatory physiology 20010101 |
| Role of mitochondrial and sarcolemmal K(ATP) channels in ischemic preconditioning of the canine heart. | American journal of physiology. Heart and circulatory physiology 20010101 |
| Acute hypertension inhibits thirst stimulated by ANG II, hyperosmolality, or hypovolemia in rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20010101 |
| Adenosine A1 receptor activation reduces reactive oxygen species and attenuates stunning in ventricular myocytes. | Journal of molecular and cellular cardiology 20010101 |
| Ischemic preconditioning with opening of mitochondrial adenosine triphosphate-sensitive potassium channels or Na/H exchange inhibition: which is the best protective strategy for heart transplants? | The Journal of thoracic and cardiovascular surgery 20010101 |
| Insulin autoimmune syndrome: the second Dutch case. | The Netherlands journal of medicine 20010101 |
| Diazoxide and trimethaphan used? | Chest 20010101 |
| Mitochondrial ATP-sensitive potassium channel plays a dominant role in ischemic preconditioning of rabbit heart. | European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20010101 |
| Intracellular potassium and chloride channels: an update. | Acta biochimica Polonica 20010101 |
| Disopyramide and its metabolite enhance insulin release from clonal pancreatic beta-cells by blocking K(ATP) channels. | Cardiovascular drugs and therapy 20010101 |
| Consequences of haemolysis without haptoglobin. | Redox report : communications in free radical research 20010101 |
| Cholelithiasis in a newborn following treatment with the somatostatin analogue octreotide. | European journal of pediatrics 20000701 |
| Dual regulation of leptin secretion: intracellular energy and calcium dependence of regulated pathway. | American journal of physiology. Endocrinology and metabolism 20000501 |
| Drugs for rapid treatment of very high blood pressure during pregnancy. | The Cochrane database of systematic reviews 20000101 |
| Modulation of beta-cell ouabain-sensitive 86Rb+ influx (Na+/K+ pump) by D-glucose, glibenclamide or diazoxide. | International journal of experimental diabetes research 20000101 |
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| Glucose regulation of islet amyloid polypeptide gene expression in rat pancreatic islets. | The American journal of physiology 19970401 |
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| Plasma renin and angiotensin II measurement in hypertensive and normal subjects: correlation of basal and stimulated states. | The Journal of clinical endocrinology and metabolism 19770701 |
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