CAS 36357-77-4 | Phosphoramidon | CAS Number 36357-77-4

Title	Journal
Neurogenic airway microvascular leakage induced by toluene inhalation in rats.	European journal of pharmacology 20120615
The investigation into indomethacin-induced potentiation of the contractile response to antigen in ovalbumin-sensitized guinea-pig tracheas.	Fundamental & clinical pharmacology 20120601
Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons.	Nature communications 20120424
In-silico characterization of ECE-1 inhibitors.	Computers in biology and medicine 20120401
Cocaine sensitization does not alter SP effects on locomotion or excitatory synaptic transmission in the NAc of rats.	Neuropharmacology 20120201
Antinociceptive effect of [Met5]enkephalin semicarbazide is not affected by dipeptidyl carboxypeptidase-I.	Journal of peptide science : an official publication of the European Peptide Society 20120201
Noninvasive near-infrared live imaging of human adult mesenchymal stem cells transplanted in a rodent model of Parkinson's disease.	International journal of nanomedicine 20120101
Adaptogens stimulate neuropeptide y and hsp72 expression and release in neuroglia cells.	Frontiers in neuroscience 20120101
Active site mutations change the cleavage specificity of neprilysin.	PloS one 20120101
Context-dependent toxicity of amyloid-β peptides on mouse cerebellar cells.	Journal of Alzheimer's disease : JAD 20120101
A mouse model for triple-negative breast cancer tumor-initiating cells (TNBC-TICs) exhibits similar aggressive phenotype to the human disease.	BMC cancer 20120101
Deficiency of ACE2 in Bone-Marrow-Derived Cells Increases Expression of TNF-α in Adipose Stromal Cells and Augments Glucose Intolerance in Obese C57BL/6 Mice.	International journal of hypertension 20120101
A smallest 6 kda metalloprotease, mini-matrilysin, in living world: a revolutionary conserved zinc-dependent proteolytic domain- helix-loop-helix catalytic zinc binding domain (ZBD).	Journal of biomedical science 20120101
Human mature adipocytes express albumin and this expression is not regulated by inflammation.	Mediators of inflammation 20120101
N-acetylcysteine for Prevention of Contrast-Induced Nephropathy: A Narrative Review.	Korean circulation journal 20111201
The role of neutral endopeptidase in caerulein-induced acute pancreatitis.	Journal of immunology (Baltimore, Md. : 1950) 20111115
Aβ-degrading enzymes: potential for treatment of Alzheimer disease.	Journal of neuropathology and experimental neurology 20111101
Analgesic mechanism of electroacupuncture in an arthritic pain model of rats: a neurotransmitter study.	Yonsei medical journal 20111101
Structure-based design of dipeptide derivatives for the human neutral endopeptidase.	Bioorganic & medicinal chemistry 20111015
Endothelium-dependent vasoconstriction in isolated vessel grafts: a novel mechanism of vasospasm?	The Annals of thoracic surgery 20111001
Endothelial angiotensin-converting enzyme and neutral endopeptidase in isolated human umbilical vein: an effective bradykinin inactivation pathway.	European journal of pharmacology 20110930
Crystal structure of Mycobacterium tuberculosis zinc-dependent metalloprotease-1 (Zmp1), a metalloprotease involved in pathogenicity.	The Journal of biological chemistry 20110916
Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection.	Nature 20110915
Dendroaspis natriuretic peptide and the designer natriuretic peptide, CD-NP, are resistant to proteolytic inactivation.	Journal of molecular and cellular cardiology 20110701
Determining protease substrate selectivity and inhibition by label-free supramolecular tandem enzyme assays.	Journal of the American Chemical Society 20110518
Cysteine cathepsins in human carious dentin.	Journal of dental research 20110401
Intranasal phosphoramidon increases beta-amyloid levels in wild-type and NEP/NEP2-deficient mice.	Journal of molecular neuroscience : MN 20110301
Acute NADPH oxidase activation potentiates cerebrovascular permeability response to bradykinin in ischemia-reperfusion.	Free radical biology & medicine 20110215
Anthrolysin O and fermentation products mediate the toxicity of Bacillus anthracis to lung epithelial cells under microaerobic conditions.	FEMS immunology and medical microbiology 20110201
Zinc metalloproteinases and amyloid Beta-Peptide metabolism: the positive side of proteolysis in Alzheimer's disease.	Biochemistry research international 20110101
Endothelin-1 expression by vascular endothelial growth factor in human umbilical vein endothelial cells and aortic smooth muscle cells.	Hypertension in pregnancy 20110101
Neprilysin-2 is an important β-amyloid degrading enzyme.	The American journal of pathology 20110101
Effect of Metal Chelators on γ-Secretase Indicates That Calcium and Magnesium Ions Facilitate Cleavage of Alzheimer Amyloid Precursor Substrate.	International journal of Alzheimer's disease 20110101
A humanin derivative reduces amyloid beta accumulation and ameliorates memory deficit in triple transgenic mice.	PloS one 20110101
A trypsin-like serine protease is involved in pseudorabies virus invasion through the basement membrane barrier of porcine nasal respiratory mucosa.	Veterinary research 20110101
Effect of Montelukast on bradykinin-induced contraction of isolated tracheal smooth muscle of guinea pig.	Indian journal of pharmacology 20110101
The major leucyl aminopeptidase of Trypanosoma cruzi (LAPTc) assembles into a homohexamer and belongs to the M17 family of metallopeptidases.	BMC biochemistry 20110101
Defective fluid secretion from submucosal glands of nasal turbinates from CFTR-/- and CFTR (ΔF508/ΔF508) pigs.	PloS one 20110101
Transgenic mice over-expressing ET-1 in the endothelial cells develop systemic hypertension with altered vascular reactivity.	PloS one 20110101
A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease.	PloS one 20110101
Noninvasive routes of proteins and peptides drug delivery.	Indian journal of pharmaceutical sciences 20110101
Bradykinin-induced lung inflammation and bronchoconstriction: role in parainfluenze-3 virus-induced inflammation and airway hyperreactivity.	The Journal of pharmacology and experimental therapeutics 20101201
Purification and biochemical characterization of a 17 kDa fibrinolytic enzyme from Schizophyllum commune.	Journal of microbiology (Seoul, Korea) 20101201
Synthesis and inhibition properties of a series of pyranose derivatives towards a Zn-metalloproteinase from Saccharomonospora canescens.	Carbohydrate research 20101102
Coronary microvascular disease in chronic Chagas cardiomyopathy including an overview on history, pathology, and other proposed pathogenic mechanisms.	PLoS neglected tropical diseases 20100801
Increased endothelial exocytosis and generation of endothelin-1 contributes to constriction of aged arteries.	Circulation research 20100723
Suppressive effects by cysteine protease inhibitors on naloxone-precipitated withdrawal jumping in morphine-dependent mice.	Neuropeptides 20100601
NEP-like endopeptidases and Alzheimer's disease [corrected].	Current Alzheimer research 20100501
Production of an antigenic peptide by insulin-degrading enzyme.	Nature immunology 20100501
The zinc-dependent protease activity of the botulinum neurotoxins.	Toxins 20100501
Diabetes-associated changes and role of N epsilon-(carboxymethyl)lysine in big ET-1-induced coronary vasoconstriction.	Peptides 20100201
Positron emission tomography of [18F]-big endothelin-1 reveals renal excretion but tissue-specific conversion to [18F]-endothelin-1 in lung and liver.	British journal of pharmacology 20100201
Phosphinic tripeptides as dual angiotensin-converting enzyme C-domain and endothelin-converting enzyme-1 inhibitors.	Journal of medicinal chemistry 20100114
The cannabinoid receptor agonist WIN 55,212-2 inhibits antigen-induced plasma extravasation in guinea pig airways.	International archives of allergy and immunology 20100101
Exploring the gain of function contribution of AKT to mammary tumorigenesis in mouse models.	PloS one 20100101
Rhinorrhea, cough and fatigue in patients taking sitagliptin.	Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20100101
The Analgesic Activity of Bestatin as a Potent APN Inhibitor.	Frontiers in neuroscience 20100101
The matrix metalloproteases and endothelin-1 in infection-associated preterm birth.	Obstetrics and gynecology international 20100101
Autocrine regulation of human sperm motility by tachykinins.	Reproductive biology and endocrinology : RB&E 20100101
Expression and function of human hemokinin-1 in human and guinea pig airways.	Respiratory research 20100101
Intrathecal substance P augments morphine-induced antinociception: possible relevance in the production of substance P N-terminal fragments.	Peptides 20090901
Neutral endopeptidase inhibition enhances substance P mediated inflammation due to hypomagnesemia.	Magnesium research 20090901
Synthesis and enzymatic evaluation of novel partially fluorinated thiol dual ACE/NEP inhibitors.	Bioorganic & medicinal chemistry letters 20090815
Functional and molecular characterization of the endothelin system in retinal arterioles.	Investigative ophthalmology & visual science 20090701
Purification and characterization of an eggshell membrane decomposing protease from Pseudomonas aeruginosa strain ME-4.	Journal of bioscience and bioengineering 20090401
Structure of human endothelin-converting enzyme I complexed with phosphoramidon.	Journal of molecular biology 20090109
Proteomic and phospho-proteomic profile of human platelets in basal, resting state: insights into integrin signaling.	PloS one 20090101
[Changes in the activity of amyloid-degrading metallopeptidases leads to disruption of memory in rats].	Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20090101
Role of the rat gastrointestinal mucosa in catabolism of endothelin peptides.	Regulatory peptides 20081129
The endothelin-converting enzyme-1/endothelin-1 pathway plays a critical role in inflammation-associated premature delivery in a mouse model.	The American journal of pathology 20081001
Role of endogenous endothelin-1 in post-ischemic cardiac dysfunction and norepinephrine overflow in rat hearts.	European journal of pharmacology 20080904
Preferential recruitment of neutrophils by endothelin-1 in acute lung inflammation induced by lipopolysaccharide or cigarette smoke.	International journal of chronic obstructive pulmonary disease 20080901
Effect of the putative novel selective ETA-receptor antagonist HJP272, a 1,3,6-trisubstituted-2-carboxy-quinol-4-one, on infection-mediated premature delivery.	Canadian journal of physiology and pharmacology 20080801
Human membrane metallo-endopeptidase-like protein degrades both beta-amyloid 42 and beta-amyloid 40.	Neuroscience 20080731
Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.	Journal of medicinal chemistry 20080724
Inhibition of neutral endopeptidase potentiates neutrophil activation during Mg-deficiency in the rat.	Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20080701
In vivo cerebrovascular effects of cocaine- and amphetamine-regulated transcript (CART) peptide.	Journal of cardiovascular pharmacology 20080701
Homology modeling and site-directed mutagenesis to identify selective inhibitors of endothelin-converting enzyme-2.	Journal of medicinal chemistry 20080626
Cysteine protease inhibitors suppress the development of tolerance to morphine antinociception.	Neuropeptides 20080601
Noxious mechanical stimulation evokes the segmental release of opioid peptides that induce mu-opioid receptor internalization in the presence of peptidase inhibitors.	Brain research 20080304
Phosphoramidon, an endothelin-converting enzyme inhibitor, attenuates lipopolysaccharide-induced acute lung injury.	Experimental lung research 20080301
Great increase in antinociceptive potency of [Leu5]enkephalin after peptidase inhibition.	Journal of pharmacological sciences 20080201
Effects of endothelin-1 1-31 on cell viabililty and [Ca2+]i in cultured neonatal rat cardiomyocytes.	Physiological research 20080101
Alzheimer disease models and human neuropathology: similarities and differences.	Acta neuropathologica 20080101
Bioinformatic analysis of the neprilysin (M13) family of peptidases reveals complex evolutionary and functional relationships.	BMC evolutionary biology 20080101
Activation of the amyloid cascade by intracerebroventricular injection of the protease inhibitor phosphoramidon.	Neuro-degenerative diseases 20080101
Activity-dependent shedding of the NMDA receptor glycine binding site by matrix metalloproteinase 3: a PUTATIVE mechanism of postsynaptic plasticity.	PloS one 20080101
A decrease in retinal progenitor cells is associated with early features of diabetic retinopathy in a model that combines diabetes and hypertension.	Molecular vision 20080101
Ozone-induced nasal hyperresponsiveness to tachykinins in guinea pigs.	American journal of rhinology 20080101
Desmoglein 2 is a substrate of kallikrein 7 in pancreatic cancer.	BMC cancer 20080101
Identifying common metalloprotease inhibitors by protein fold types using Fourier transform mass spectrometry.	Bioorganic & medicinal chemistry letters 20071201
Metabolic inactivation of the circadian transmitter, pigment dispersing factor (PDF), by neprilysin-like peptidases in Drosophila.	The Journal of experimental biology 20071201
[Ixeris sonchifolia induced vasoconstriction effect and its mechanism in rat thoracic aorta].	Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071201
The peptidase inhibitor CGS-26303 increases endothelin converting enzyme-1 expression in endothelial cells through accumulation of big endothelin-1.	British journal of pharmacology 20071001
Characterisation of endothelin converting enzyme-1 shedding from endothelial cells.	FEBS letters 20070918
The enhancing effects of peptidase inhibitors on the antinociceptive action of [Met5]enkephalin-Arg6-Phe7 in rats.	Journal of pharmacological sciences 20070901
Reducing amyloid plaque burden via ex vivo gene delivery of an Abeta-degrading protease: a novel therapeutic approach to Alzheimer disease.	PLoS medicine 20070801
Potentiation of bradykinin effect by angiotensin-converting enzyme inhibition does not correlate with angiotensin-converting enzyme activity in the rat mesenteric arteries.	Hypertension (Dallas, Tex. : 1979) 20070701
Expression of neutral endopeptidase (NEP/CD10) on pancreatic tumor cell lines, pancreatitis and pancreatic tumor tissues.	International journal of cancer 20070601
Cardiovascular effects of centrally applied endothelin-1 1-31 and its relationship to endothelin-1 1-21 in rats.	Autonomic neuroscience : basic & clinical 20070530
Functional evidence of des-Arg10-kallidin enzymatic inactivating pathway in isolated human umbilical vein.	Naunyn-Schmiedeberg's archives of pharmacology 20070501
Antagonism of phosphoramidon-induced antinociception in mice by mu- but not kappa-opioid receptor blockers.	Life sciences 20070417
Effect of chronic ethanol consumption on endothelin-1 generation and conversion of exogenous big-endothelin-1 by the rat carotid artery.	Alcohol (Fayetteville, N.Y.) 20070301
Neutral endopeptidase up-regulation in isolated human umbilical artery: involvement in desensitization of bradykinin-induced vasoconstrictor effects.	The Journal of pharmacology and experimental therapeutics 20070201
Expression of NEP2, a soluble neprilysin-like endopeptidase, during embryogenesis in Drosophila melanogaster.	Peptides 20070101
Central and peripheral mechanisms of narcotic antitussives: codeine-sensitive and -resistant coughs.	Cough (London, England) 20070101
Inhibition of neutral endopeptidase by thiorphan does not modify coronary vascular responses to angiotensin I, angiotensin II and bradykinin in the isolated guinea pig heart.	Pharmacological reports : PR 20070101
Big ET-1 processing into vasoactive peptides in arteries and veins.	Vascular pharmacology 20070101
Activation of the neurokinin-1 receptor by substance P triggers the release of substance P from cultured adult rat dorsal root ganglion neurons.	Molecular pain 20070101
Neprilysin protects human neuronal progenitor cells against impaired development caused by amyloid-beta peptide.	Brain research 20061208
Preparation of a protected phosphoramidon precursor via an H-phosphonate coupling strategy.	Bioorganic & medicinal chemistry letters 20061101
Effects of big endothelin-1 in comparison with endothelin-1 on the microvascular blood flow velocity and diameter of rat mesentery in vivo.	Microvascular research 20061101
Involvement of endothelial thromboxane A2 in the vasoconstrictor response induced by 15-E2t-isoprostane in isolated human umbilical vein.	Naunyn-Schmiedeberg's archives of pharmacology 20060801
Enzymatic pathways involved in the generation of endothelin-1(1-31) from exogenous big endothelin-1 in the rabbit aorta.	British journal of pharmacology 20060601
Arrhythmogenic action of endothelin-1(1-31) through conversion to endothelin-1(1-21).	Experimental biology and medicine (Maywood, N.J.) 20060601
Angiotensin converting enzyme has an inhibitory role in CGRP metabolism in human skin.	Peptides 20060401
Phosphodiesterase 5 inhibitor ameliorates renal resistance to atrial natriuretic peptide associated with obesity and hyperleptinemia.	Archives of medical research 20060401
Phosphodiesterase IV and neutral endopeptidase in airways from developing and allergen sensitized rabbits.	Pulmonary pharmacology & therapeutics 20060101
Acceleration of epithelial cell syndecan-1 shedding by anthrax hemolytic virulence factors.	BMC microbiology 20060101
Presenilin-dependent intramembrane cleavage of ephrin-B1.	Molecular neurodegeneration 20060101
beta-Amyloid degradation and Alzheimer's disease.	Journal of biomedicine & biotechnology 20060101
Blood pressure responses of endothelin-1 1-31 within the rostral ventrolateral medulla through conversion to endothelin-1 1-21.	Journal of cardiovascular pharmacology 20051201
Role of endothelin-1-dependent up-regulation of leptin in oral mucosal repair.	Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20051201
Endothelin-1-dependent leptin induction in gastric mucosal inflammatory responses to Helicobacter pylori lipopolysaccharide.	Biochemical and biophysical research communications 20051104
Neutral endopeptidase (EC 3.4.24.11) in cirrhotic liver: a new target to treat portal hypertension?	Journal of hepatology 20051101
Cocaine- and amphetamine-regulated transcript (CART) peptide: a vasoactive role in the cerebral circulation.	Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20051001
NEP inhibitors enhance C-type natriuretic peptide-induced relaxation in porcine isolated coronary artery.	Vascular pharmacology 20051001
Inhibition of neutral endopeptidase (NEP) facilitates neurogenic inflammation.	Experimental neurology 20050901
Neutral endopeptidase determines the severity of pancreatitis-associated lung injury.	The Journal of surgical research 20050901
Localization of endothelin-converting enzyme in bovine optic nerve and retina.	Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20050801
Up-regulation in endothelin-1 by Helicobacter pylori lipopolysaccharide interferes with gastric mucin synthesis via epidermal growth factor receptor transactivation.	Scandinavian journal of gastroenterology 20050801
The endothelin B (ETB) receptor agonist IRL 1620 is highly vasoconstrictive in two syngeneic rat tumour lines: potential for selective tumour blood flow modification.	British journal of cancer 20050711
Endothelin-1 (1-31) is an intermediate in the production of endothelin-1 after big endothelin-1 administration in vivo.	Hypertension (Dallas, Tex. : 1979) 20050701
Contribution of endogenous endothelin-1 to basal vascular tone during normal pregnancy and preeclampsia.	American journal of obstetrics and gynecology 20050701
The Kell protein of the common K2 phenotype is a catalytically active metalloprotease, whereas the rare Kell K1 antigen is inactive. Identification of novel substrates for the Kell protein.	The Journal of biological chemistry 20050603
Characterization of endothelin-converting enzyme activities in ARPE-19 cells, a human retinal pigmented epithelial cell line.	Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20050601
Cardiac myocytes control release of endothelin-1 in coronary vasculature.	American journal of physiology. Heart and circulatory physiology 20050501
The role of substance P and bradykinin in the cough reflex and bronchoconstriction in guinea-pigs.	European journal of pharmacology 20050418
Involvement of endothelin and nitric oxide in cyclosporine A-induced contractions in guinea pig isolated gallbladder strips.	Pharmacological research 20050301
Activation of the nociceptin/orphanin FQ receptor reduces bronchoconstriction and microvascular leakage in a rabbit model of gastroesophageal reflux.	British journal of pharmacology 20050301
Purification, characterization cloning, and sequencing of metalloendopeptidase from Streptomyces septatus TH-2.	Archives of biochemistry and biophysics 20050215
Renal responses to atrial natriuretic peptide are preserved in bilateral ureteral obstruction and augmented by neutral endopeptidase inhibition.	The Journal of urology 20050201
Endothelin-converting enzyme-1 inhibition and growth of human glioblastoma cells.	Journal of medicinal chemistry 20050127
Down-regulation does not mediate natriuretic peptide-dependent desensitization of natriuretic peptide receptor (NPR)-A or NPR-B: guanylyl cyclase-linked natriuretic peptide receptors do not internalize.	Molecular pharmacology 20050101
Effective antiprotease-antibiotic treatment of experimental anthrax.	BMC infectious diseases 20050101
Tezosentan reduces the microvascular filtration coefficient in isolated lungs from rats subjected to cecum ligation and puncture.	Critical care (London, England) 20050101
Endothelin-1-dependent up-regulation of leptin production in gastric mucosal injury by indomethacin.	Inflammopharmacology 20050101
Long-lasting smooth-muscle relaxation by a novel PACAP analogue in human bronchi.	Regulatory peptides 20041215
Further evidence on the anxiogenic-like effect of substance P evaluated in the elevated plus-maze in rats.	Behavioural brain research 20041005
Specificity comparison of a serine endopeptidase (SH1) and a serine thiol endopeptidase (STH2) purified from human urine.	The international journal of biochemistry & cell biology 20041001
Despite minimal hemodynamic alterations endotoxemia modulates NOS and p38-MAPK phosphorylation via metalloendopeptidases.	Molecular and cellular biochemistry 20041001
Porphyromonas gingivalis lipopolysaccharide-induced up-regulation in endothelin-1 interferes with salivary mucin synthesis via epidermal growth factor receptor transactivation.	IUBMB life 20041001
Interleukin-1beta attenuates endothelin B receptor-mediated airway contractions in a murine in vitro model of asthma: roles of endothelin converting enzyme and mitogen-activated protein kinase pathways.	Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040901
[Physiological and pathophysiological roles of the endothelin converting enzymes].	Nihon rinsho. Japanese journal of clinical medicine 20040901
Involvement of MAP-kinase, PI3-kinase and EGF-receptor in the stimulatory effect of Neurotensin on DNA synthesis in PC3 cells.	Regulatory peptides 20040815
Degradation of pulmonary surfactant protein D by Pseudomonas aeruginosa elastase abrogates innate immune function.	The Journal of biological chemistry 20040716
Obligatory role for endogenous endothelin in mediating the hypertrophic effects of phenylephrine and angiotensin II in neonatal rat ventricular myocytes: evidence for two distinct mechanisms for endothelin regulation.	The Journal of pharmacology and experimental therapeutics 20040701
Hypoxia augments TNF-alpha-mediated endothelin-1 release and cell proliferation in human optic nerve head astrocytes.	Biochemical and biophysical research communications 20040604
Endothelins and their inhibition in the human skin microcirculation: ET[1-31], a new vasoconstrictor peptide.	British journal of clinical pharmacology 20040601
Endothelin-induced constriction of the ductus venosus in fetal sheep: developmental aspects and possible interaction with vasodilatory prostaglandin.	British journal of pharmacology 20040601
[Endothelin].	Nihon rinsho. Japanese journal of clinical medicine 20040601
A continuous spectrophotometric assay for Pseudomonas aeruginosa LasA protease (staphylolysin) using a two-stage enzymatic reaction.	Analytical biochemistry 20040515
Occurrence of substance P(1-7) in the metabolism of substance P and its antinociceptive activity at the mouse spinal cord level.	Methods and findings in experimental and clinical pharmacology 20040401
Nociceptin inhibits airway microvascular leakage induced by HCl intra-oesophageal instillation.	British journal of pharmacology 20040301
The effect of phosphoramidon on inflammation-mediated preterm delivery in a mouse model.	American journal of obstetrics and gynecology 20040201
Signal pathway involved in increased expression of neutral endopeptidase 24.11 by gonadotropin releasing hormone in choriocarcinoma cells.	Placenta 20040101
Liver-specific expression of the agouti gene in transgenic mice promotes liver carcinogenesis in the absence of obesity and diabetes.	Molecular cancer 20040101
[The new class of drugs-- metalloprotease inhibitors -- in the treatment of heart failure].	Klinicheskaia meditsina 20040101
Essential role for vascular gelatinase activity in relaxin-induced renal vasodilation, hyperfiltration, and reduced myogenic reactivity of small arteries.	Circulation research 20031212
A low dose of angiotensin II increases inotropism through activation of reverse Na(+)/Ca(2+) exchange by endothelin release.	Cardiovascular research 20031201
[Protective effects of phosphoramidon on the experimental myocardial injury in rats].	Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 20031201
Active amino acids of the Kell blood group protein and model of the ectodomain based on the structure of neutral endopeptidase 24.11.	Blood 20031015
Aminopeptidases function as endocytic receptors in the trophotaenial placenta of the goodeid fish, Ameca splendens (Teleostei: Atheriniformes).	Journal of experimental zoology. Part A, Comparative experimental biology 20031001
Metalloendopeptidase inhibition regulates phosphorylation of p38-mitogen-activated protein kinase and nitric oxide synthase in heart after endotoxemia.	Shock (Augusta, Ga.) 20031001
The role of endothelin converting enzyme inhibition during group B streptococcus-induced pulmonary hypertension in newborn piglets.	Pediatric research 20030901
CD10 is a key enzyme involved in the activation of tumor-activated peptide prodrug CPI-0004Na and novel analogues: implications for the design of novel peptide prodrugs for the therapy of CD10+ tumors.	Cancer research 20030901
Cerebral angiogenesis and expression of VEGF after subarachnoid hemorrhage (SAH) in rats.	Brain research 20030815
Isolation and characterization of a zinc-containing metalloprotease expressed by Vibrio tubiashii.	Canadian journal of microbiology 20030801
The effects of phosphoramidon on the expression of human endothelin-converting enzyme-1 (ECE-1) isoforms.	Journal of cardiovascular pharmacology 20030701
Crucial role of extracellular signal-regulated kinase pathway in reactive oxygen species-mediated endothelin-1 gene expression induced by endothelin-1 in rat cardiac fibroblasts.	Molecular pharmacology 20030501
Pathways and kinetics of deslorelin degradation in an airway epithelial cell line (Calu-1).	Pharmaceutical research 20030501
[D-Val22]big ET-1[16-38] inhibits endothelin-converting enzyme activity: a promising concept in the prevention of cerebral vasospasm.	Neurosurgical review 20030501
Pseudomonas aeruginosa elastase degrades surfactant proteins A and D.	American journal of respiratory cell and molecular biology 20030401
Vasospasm following subarachnoid hemorrhage: evidence against functional upregulation of protein kinase C constrictor pathway.	Neurological research 20030401
Binding of a new bioactive 31-amino-acid endothelin-1 to an endothelin ET(B) or ET(B)-like receptor in porcine lungs.	European journal of pharmacology 20030328
Peptidases prevent mu-opioid receptor internalization in dorsal horn neurons by endogenously released opioids.	The Journal of neuroscience : the official journal of the Society for Neuroscience 20030301
The formyl peptide N-formyl-methionyl-leucyl-phenylalanine downregulates the expression of FcgammaRs in interferon-gamma-activated monocytes/macrophages in vitro and in vivo.	Scandinavian journal of immunology 20030301
Identification and localization of a neprilysin-like activity that degrades tachykinin-related peptides in the brain of the cockroach, Leucophaea maderae, and locust, Locusta migratoria.	The Journal of comparative neurology 20030224
Effects of kinins on mammalian spermatozoa and the impact of peptidolytic enzymes.	Andrologia 20030201
Effect of endothelin-1 (1-31) on the renal resistance vessels.	The journal of medical investigation : JMI 20030201
Role of tachykinins in the bronchoconstriction induced by HCl intraesophageal instillation in the rabbit.	Life sciences 20030124
Action of three ectopeptidases on corticotropin-releasing factor: metabolism and functional aspects.	Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030101
Attenuation of renal ischemia/reperfusion injury by a triple drug combination therapy.	Journal of nephrology 20030101
Mechanical stretch-induced mitogen-activated protein kinase activation is mediated via angiotensin and endothelin systems in vascular smooth muscle cells.	Biological & pharmaceutical bulletin 20021201
High-performance liquid chromatographic separation of renin-angiotensin system peptides and most of their metabolic fragments.	Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20021125
Role of abnormal neutral endopeptidase-like activities in Hyp mouse bone cells in renal phosphate transport.	American journal of physiology. Cell physiology 20021101
Cardioprotective effects of phosphoramidon on myocardial structure and function in murine Chagas' disease.	International journal for parasitology 20021101
The mechanisms for tachykinin-induced contractions of the rabbit corpus cavernosum.	British journal of pharmacology 20021101
Extracellular peptidases of imaginal discs of Drosophila melanogaster.	Peptides 20021101
Effect of endothelin-converting enzyme inhibitors on big endothelin-1 induced contraction in isolated rat basilar artery.	Acta neurochirurgica 20021101
Combination therapy of N-acetylcysteine, sodium nitroprusside and phosphoramidon attenuates ischemia-reperfusion injury in rat kidney.	Molecular and cellular biochemistry 20021101
Attenuation of ischemia/reperfusion induced MAP kinases by N-acetyl cysteine, sodium nitroprusside and phosphoramidon.	Molecular and cellular biochemistry 20021101
[Met5]enkephalin-Arg-Gly-Leu-induced antinociception is greatly increased by peptidase inhibitors.	European journal of pharmacology 20021018
The increased proliferation of cultured neuroblastoma cells treated with vasoactive intestinal peptide is enhanced by simultaneous inhibition of neutral endopeptidase.	Regulatory peptides 20021015
Degradation of nociceptin (orphanin FQ) by mouse spinal cord synaptic membranes is triggered by endopeptidase-24.11: an in vitro and in vivo study.	Biochemical pharmacology 20021015
Bradykinin potentiation by ACE inhibitors: a matter of metabolism.	British journal of pharmacology 20020901
Effect of quercetin on plasma extravasation in rat CNS and dura mater by ACE and NEP inhibition.	Phytotherapy research : PTR 20020901
Effect of glycerol on endothelium-derived factors in the vasculature of the rabbit kidney.	Clinical and experimental pharmacology & physiology 20020801
Endothelin-converting enzyme activity in human cerebral circulation.	Neurosurgery 20020801
Characterization of PgPepO, a bacterial homologue of endothelin-converting enzyme-1.	Clinical science (London, England : 1979) 20020801
Expression, purification and characterization of the monomeric and dimeric forms of soluble bovine endothelin converting enzyme-1a.	Clinical science (London, England : 1979) 20020801
Phosphoramidon treatment improves the consequences of chagasic heart disease in mice.	Clinical science (London, England : 1979) 20020801
Tachykinins and airway microvascular leakage induced by HCl intra-oesophageal instillation.	The European respiratory journal 20020801
Induction of apoptosis and CD10/neutral endopeptidase expression by jaspamide in HL-60 line cells.	Cellular and molecular life sciences : CMLS 20020801
Pressor and pulmonary responses to ET-1(1-31) in guinea-pigs.	British journal of pharmacology 20020701
Possible involvement of placental peptidases that degrade gonadotropin-releasing hormone (GnRH) in the dynamic pattern of placental hCG secretion via GnRH degradation.	Placenta 20020701
Vasospasm following subarachnoid hemorrhage: evidence against functional upregulation of Rho kinase constrictor pathway.	Neurological research 20020601
Efficient transesterification of sucrose catalysed by the metalloprotease thermolysin in dimethylsulfoxide.	FEBS letters 20020522
Inhibition of endothelin-1 improves survival and vasculopathy in rat cardiac transplants treated with cyclosporine.	Transplantation 20020415
Inactivation of a tachykinin-related peptide: identification of four neuropeptide-degrading enzymes in neuronal membranes of insects from four different orders.	Peptides 20020401
Substance P induced preprotachykinin-a mRNA, neutral endopeptidase mRNA and substance P in cultured normal fibroblasts.	International archives of allergy and immunology 20020401
Enhancement of neurokinin A-induced smooth muscle contraction in human urinary bladder by mucosal removal and phosphoramidon: relationship to peptidase inhibition.	European journal of pharmacology 20020308
ET(A) and ET(B) receptors modulate the proliferation of human pulmonary artery smooth muscle cells.	American journal of respiratory and critical care medicine 20020201
Neprilysin inhibitors potentiate effects of bradykinin on b2 receptor.	Hypertension (Dallas, Tex. : 1979) 20020201
Endothelin-1[1-31]: a novel autocrine-paracrine regulator of human adrenal cortex secretion and growth.	The Journal of clinical endocrinology and metabolism 20020101
Endothelin-converting enzyme activity in vascular smooth muscle preparations in vitro.	Methods in molecular biology (Clifton, N.J.) 20020101
Mycosin-1, a subtilisin-like serine protease of Mycobacterium tuberculosis, is cell wall-associated and expressed during infection of macrophages.	BMC microbiology 20020101
Vascular endothelin converting enzyme-1 expression and activity is upregulated in clinical diabetes.	Ethnicity & disease 20020101
Zinc and Manduca sexta hemocyte functions.	Journal of insect science (Online) 20020101
Abstracts of the Fourth International Symposium on Molecular Insect Science. May 28-June 2, 2002. Tucson, Arizona, USA.	Journal of insect science (Online) 20020101
Tachykinin NK(3) receptor agonists induced microvascular leakage hypersensitivity in the guinea-pig airways.	European journal of pharmacology 20011221
Soluble recombinant neprilysin induces aggrecanase-mediated cleavage of aggrecan in cartilage explant cultures.	Archives of biochemistry and biophysics 20011215
The role of substance P release in the lung with esophageal acid.	The American journal of medicine 20011203
Effect of neutral endopeptidase inhibitor on bradykinin-induced bronchoconstriction.	Life sciences 20011121
Relaxation and modulation of cyclic AMP production in response to atrial natriuretic peptides in guinea pig tracheal smooth muscle.	European journal of pharmacology 20011102
Vasoconstrictor activity of novel endothelin peptide, ET-1(1 - 31), in human mammary and coronary arteries in vitro.	British journal of pharmacology 20011101
In vitro contractile effects of neurokinin receptor blockade in the human ureter.	The Journal of urology 20011001
Differential effects of U46619 on renal regional hemodynamics in the rat: involvement of endothelin.	The Journal of pharmacology and experimental therapeutics 20011001
Determination of bradykinin in rat urine by coupled-column high pressure liquid chromatography with precolumn derivatization with a water-soluble fluorogenic reagent.	Analytical biochemistry 20011001
Roles of mast cells and sensory nerves in cutaneous vascular hyperpermeability and scratching behavior induced by poly-L-arginine in rats.	European journal of pharmacology 20010817
A proteinase inhibitor decreases tumor growth in a laparoscopic rat model.	Surgical endoscopy 20010801
Deletion of neutral endopeptidase exacerbates intestinal inflammation induced by Clostridium difficile toxin A.	American journal of physiology. Gastrointestinal and liver physiology 20010801
Changes in the expression of tachykinin receptors in the rat uterus during the course of pregnancy.	Biology of reproduction 20010801
Effect of quercetin on tachykinin-induced plasma extravasation in rat urinary bladder.	Phytotherapy research : PTR 20010801
Immune complexes (IC) down-regulate the basal and interferon-gamma-induced expression of MHC class II on human monocytes.	Clinical and experimental immunology 20010801
Apparent B-type natriuretic peptide selectivity in the kidney due to differential processing.	Canadian journal of physiology and pharmacology 20010801
Degradation of the Alzheimer's amyloid beta peptide by endothelin-converting enzyme.	The Journal of biological chemistry 20010706
Bradykinin augments fibroblast-mediated contraction of released collagen gels.	American journal of physiology. Lung cellular and molecular physiology 20010701
Upregulation of neutral endopeptidase expression and enzymatic activity during the differentiation of human choriocarcinoma cells.	Placenta 20010701
Endogenously released endothelin-1 from human pulmonary artery smooth muscle promotes cellular proliferation: relevance to pathogenesis of pulmonary hypertension and vascular remodeling.	American journal of respiratory cell and molecular biology 20010701
Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases.	The Journal of biological chemistry 20010615
Soluble CD44 inhibits melanoma tumor growth by blocking cell surface CD44 binding to hyaluronic acid.	Oncogene 20010607
Tachykinin-induced bronchoconstriction in sheep is NK-1 receptor mediated and exhibits tachyphylaxis.	Respirology (Carlton, Vic.) 20010601
Effect of ECE and NEP inhibition on cigarette smoke-induced cell proliferation in the rat lung.	Inhalation toxicology 20010601
Purification and characterization of a 43.5 kDa keratinolytic metalloprotease from Microsporum canis.	Medical mycology 20010601
Endothelium-dependent relaxation in response to low concentrations of bradykinin is enhanced by phosphoramidon, bosentan and BQ-123 in bovine coronary arteries in vitro.	Japanese journal of pharmacology 20010601
Airway hyperresponsiveness to bronchoconstrictor challenge after wood smoke exposure in guinea pigs.	Life sciences 20010518
The role of endothelin in the pathogenesis of Chagas' disease.	International journal for parasitology 20010501
Pulmonary adrenomedullin counteracts deterioration of coronary flow and myocardial performance evoked by pulmonary endothelins in experimental acute respiratory distress syndrome.	Critical care medicine 20010501
The lungs as an anti-inflammatory organ of the body.	Critical care medicine 20010501
A three-dimensional model of endothelin-converting enzyme (ECE) based on the X-ray structure of neutral endopeptidase 24.11 (NEP).	Protein engineering 20010501
Isoprostaglandin E2 type-III (8-iso-prostaglandin E2) evoked contractions in the human internal mammary artery.	Life sciences 20010413
Mechanisms underlying increased release of endothelin-1 from aorta in diabetic rats.	Peptides 20010401
Phosphoramidon-sensitive endothelin-converting enzymes modulate cerebral blood flow and neural damage of hypoxic rats.	Neuroscience letters 20010330
Reverse mode of the Na+-Ca2+ exchange after myocardial stretch: underlying mechanism of the slow force response.	Circulation research 20010302
The neprilysin (NEP) family of zinc metalloendopeptidases: genomics and function.	BioEssays : news and reviews in molecular, cellular and developmental biology 20010301
Interactions of human matrix metalloproteinase 7 (matrilysin) with the inhibitors thiorphan and R-94138.	Journal of biochemistry 20010301
Characterization of increased cough sensitivity after antigen challenge in guinea pigs.	Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20010301
Antinociceptive effect produced by intracerebroventricularly administered dynorphin A is potentiated by p-hydroxymercuribenzoate or phosphoramidon in the mouse formalin test.	Brain research 20010209
Chronic tobacco smoke exposure increases airway sensitivity to capsaicin in awake guinea pigs.	Journal of applied physiology (Bethesda, Md. : 1985) 20010201
Neutral endopeptidase terminates substance P-induced inflammation in allergic contact dermatitis.	Journal of immunology (Baltimore, Md. : 1950) 20010115
Mitogen-activated protein kinase activity regulation role of angiotensin and endothelin systems in vascular smooth muscle cells.	European journal of pharmacology 20010105
NK2 tachykinin receptors mediate contraction of the pig intravesical ureter: tachykinin-induced enhancement of non-adrenergic non-cholinergic excitatory neurotransmission.	Neurourology and urodynamics 20010101
Effect of phosphoramidon on brain tissue angiogenesis in the chronic phase of vasospasm after subarachnoid hemorrhage in the rat.	Medical science monitor : international medical journal of experimental and clinical research 20010101
Role of endothelin-converting enzyme-1 in the suppression of constitutive nitric oxide synthase in rat gastric mucosal injury by indomethacin.	Scandinavian journal of gastroenterology 20001101
Pharmacological characterization of a novel sulfonylureid-pyrazole derivative, SM-19712, a potent nonpeptidic inhibitor of endothelin converting enzyme.	Japanese journal of pharmacology 20000901
Potent and selective non-peptidic inhibitors of endothelin-converting enzyme-1 with sustained duration of action.	Journal of medicinal chemistry 20000210
Morphine preconditioning attenuates neutrophil activation in rat models of myocardial infarction.	Cardiovascular research 19981201
Acute and chronic effects of capsaicin in perfused rat muscle: the role of tachykinins and calcitonin gene-related peptide.	The Journal of pharmacology and experimental therapeutics 19981101
Influence of several peptidase inhibitors on the pro-inflammatory effects of substance P, capsaicin and collagenase.	Naunyn-Schmiedeberg's archives of pharmacology 19961101
In vitro metabolism of an insect neuropeptide by neural membrane preparations from Lymantria dispar.	Peptides 19960101
Regulation of N-formyl-methionyl-leucyl-phenylalanine receptor recycling by surface membrane neutral endopeptidase-mediated degradation of ligand.	Journal of leukocyte biology 19951001
Brain cathepsin B but not metalloendopeptidases degrade rAPP751 with production of amyloidogenic fragments. Comparison with synthetic peptides emulating beta- and gamma-secretase sites.	International journal of peptide and protein research 19950101
Purification and characterization of a neutral zinc endopeptidase secreted by Flavobacterium meningosepticum.	Archives of biochemistry and biophysics 19940515
Profile of capsaicin-induced mouse ear oedema as neurogenic inflammatory model: comparison with arachidonic acid-induced ear oedema.	British journal of pharmacology 19931201
Degradation of bradykinin by neutral endopeptidase (EC 3.4.24.11) in cultured human endothelial cells.	European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies 19930501
Jurkat T cells express a functional neutral endopeptidase activity (CALLA) involved in T cell activation.	The EMBO journal 19921101
Functional reactivity of different central opioid receptor systems following clomipramine treatments.	Pharmacological research 19900101
Neuropeptide-degrading endopeptidase activity of locust (Schistocerca gregaria) synaptic membranes.	The Biochemical journal 19881101
Effects of bestatin and phosphoramidon on the hypertensive response to physostigmine in the rat.	Fundamental & clinical pharmacology 19870101
Enkephalinase inhibition suppresses naloxone-induced jumping in morphine-dependent mice.	Archives internationales de pharmacodynamie et de therapie 19861001

Antinociceptive effect of [Met5]enkephalin semicarbazide is not affected by dipeptidyl carboxypeptidase-I.

Journal of peptide science : an official publication of the European Peptide Society 20120201

Noninvasive near-infrared live imaging of human adult mesenchymal stem cells transplanted in a rodent model of Parkinson's disease.

International journal of nanomedicine 20120101

Adaptogens stimulate neuropeptide y and hsp72 expression and release in neuroglia cells.

Frontiers in neuroscience 20120101

Active site mutations change the cleavage specificity of neprilysin.

PloS one 20120101

Context-dependent toxicity of amyloid-β peptides on mouse cerebellar cells.

Journal of Alzheimer's disease : JAD 20120101

A mouse model for triple-negative breast cancer tumor-initiating cells (TNBC-TICs) exhibits similar aggressive phenotype to the human disease.

BMC cancer 20120101

Deficiency of ACE2 in Bone-Marrow-Derived Cells Increases Expression of TNF-α in Adipose Stromal Cells and Augments Glucose Intolerance in Obese C57BL/6 Mice.

International journal of hypertension 20120101

A smallest 6 kda metalloprotease, mini-matrilysin, in living world: a revolutionary conserved zinc-dependent proteolytic domain- helix-loop-helix catalytic zinc binding domain (ZBD).

Journal of biomedical science 20120101

Human mature adipocytes express albumin and this expression is not regulated by inflammation.

Mediators of inflammation 20120101

N-acetylcysteine for Prevention of Contrast-Induced Nephropathy: A Narrative Review.

Korean circulation journal 20111201

The role of neutral endopeptidase in caerulein-induced acute pancreatitis.

Journal of immunology (Baltimore, Md. : 1950) 20111115

Aβ-degrading enzymes: potential for treatment of Alzheimer disease.

Journal of neuropathology and experimental neurology 20111101

Analgesic mechanism of electroacupuncture in an arthritic pain model of rats: a neurotransmitter study.

Yonsei medical journal 20111101

Structure-based design of dipeptide derivatives for the human neutral endopeptidase.

Bioorganic & medicinal chemistry 20111015

Endothelium-dependent vasoconstriction in isolated vessel grafts: a novel mechanism of vasospasm?

The Annals of thoracic surgery 20111001

Endothelial angiotensin-converting enzyme and neutral endopeptidase in isolated human umbilical vein: an effective bradykinin inactivation pathway.

European journal of pharmacology 20110930

Crystal structure of Mycobacterium tuberculosis zinc-dependent metalloprotease-1 (Zmp1), a metalloprotease involved in pathogenicity.

The Journal of biological chemistry 20110916

Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection.

Nature 20110915

Dendroaspis natriuretic peptide and the designer natriuretic peptide, CD-NP, are resistant to proteolytic inactivation.

Journal of molecular and cellular cardiology 20110701

Determining protease substrate selectivity and inhibition by label-free supramolecular tandem enzyme assays.

Journal of the American Chemical Society 20110518

Cysteine cathepsins in human carious dentin.

Journal of dental research 20110401

Intranasal phosphoramidon increases beta-amyloid levels in wild-type and NEP/NEP2-deficient mice.

Journal of molecular neuroscience : MN 20110301

Acute NADPH oxidase activation potentiates cerebrovascular permeability response to bradykinin in ischemia-reperfusion.

Free radical biology & medicine 20110215

Anthrolysin O and fermentation products mediate the toxicity of Bacillus anthracis to lung epithelial cells under microaerobic conditions.

FEMS immunology and medical microbiology 20110201

Zinc metalloproteinases and amyloid Beta-Peptide metabolism: the positive side of proteolysis in Alzheimer's disease.

Biochemistry research international 20110101

Endothelin-1 expression by vascular endothelial growth factor in human umbilical vein endothelial cells and aortic smooth muscle cells.

Hypertension in pregnancy 20110101

Neprilysin-2 is an important β-amyloid degrading enzyme.

The American journal of pathology 20110101

Effect of Metal Chelators on γ-Secretase Indicates That Calcium and Magnesium Ions Facilitate Cleavage of Alzheimer Amyloid Precursor Substrate.

International journal of Alzheimer's disease 20110101

A humanin derivative reduces amyloid beta accumulation and ameliorates memory deficit in triple transgenic mice.

PloS one 20110101

A trypsin-like serine protease is involved in pseudorabies virus invasion through the basement membrane barrier of porcine nasal respiratory mucosa.

Veterinary research 20110101

Effect of Montelukast on bradykinin-induced contraction of isolated tracheal smooth muscle of guinea pig.

Indian journal of pharmacology 20110101

The major leucyl aminopeptidase of Trypanosoma cruzi (LAPTc) assembles into a homohexamer and belongs to the M17 family of metallopeptidases.

BMC biochemistry 20110101

Defective fluid secretion from submucosal glands of nasal turbinates from CFTR-/- and CFTR (ΔF508/ΔF508) pigs.

PloS one 20110101

Transgenic mice over-expressing ET-1 in the endothelial cells develop systemic hypertension with altered vascular reactivity.

PloS one 20110101

A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease.

PloS one 20110101

Noninvasive routes of proteins and peptides drug delivery.

Indian journal of pharmaceutical sciences 20110101

Bradykinin-induced lung inflammation and bronchoconstriction: role in parainfluenze-3 virus-induced inflammation and airway hyperreactivity.

The Journal of pharmacology and experimental therapeutics 20101201

Purification and biochemical characterization of a 17 kDa fibrinolytic enzyme from Schizophyllum commune.

Journal of microbiology (Seoul, Korea) 20101201

Synthesis and inhibition properties of a series of pyranose derivatives towards a Zn-metalloproteinase from Saccharomonospora canescens.

Carbohydrate research 20101102

Coronary microvascular disease in chronic Chagas cardiomyopathy including an overview on history, pathology, and other proposed pathogenic mechanisms.

PLoS neglected tropical diseases 20100801

Increased endothelial exocytosis and generation of endothelin-1 contributes to constriction of aged arteries.

Circulation research 20100723

Suppressive effects by cysteine protease inhibitors on naloxone-precipitated withdrawal jumping in morphine-dependent mice.

Neuropeptides 20100601

NEP-like endopeptidases and Alzheimer's disease [corrected].

Current Alzheimer research 20100501

Production of an antigenic peptide by insulin-degrading enzyme.

Nature immunology 20100501

The zinc-dependent protease activity of the botulinum neurotoxins.

Toxins 20100501

Diabetes-associated changes and role of N epsilon-(carboxymethyl)lysine in big ET-1-induced coronary vasoconstriction.

Peptides 20100201

Positron emission tomography of [18F]-big endothelin-1 reveals renal excretion but tissue-specific conversion to [18F]-endothelin-1 in lung and liver.

British journal of pharmacology 20100201

Phosphinic tripeptides as dual angiotensin-converting enzyme C-domain and endothelin-converting enzyme-1 inhibitors.

Journal of medicinal chemistry 20100114

The cannabinoid receptor agonist WIN 55,212-2 inhibits antigen-induced plasma extravasation in guinea pig airways.

International archives of allergy and immunology 20100101

Exploring the gain of function contribution of AKT to mammary tumorigenesis in mouse models.

PloS one 20100101

Rhinorrhea, cough and fatigue in patients taking sitagliptin.

Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20100101

The Analgesic Activity of Bestatin as a Potent APN Inhibitor.

Frontiers in neuroscience 20100101

The matrix metalloproteases and endothelin-1 in infection-associated preterm birth.

Obstetrics and gynecology international 20100101

Autocrine regulation of human sperm motility by tachykinins.

Reproductive biology and endocrinology : RB&E 20100101

Expression and function of human hemokinin-1 in human and guinea pig airways.

Respiratory research 20100101

Intrathecal substance P augments morphine-induced antinociception: possible relevance in the production of substance P N-terminal fragments.

Peptides 20090901

Neutral endopeptidase inhibition enhances substance P mediated inflammation due to hypomagnesemia.

Magnesium research 20090901

Synthesis and enzymatic evaluation of novel partially fluorinated thiol dual ACE/NEP inhibitors.

Bioorganic & medicinal chemistry letters 20090815

Functional and molecular characterization of the endothelin system in retinal arterioles.

Investigative ophthalmology & visual science 20090701

Purification and characterization of an eggshell membrane decomposing protease from Pseudomonas aeruginosa strain ME-4.

Journal of bioscience and bioengineering 20090401

Structure of human endothelin-converting enzyme I complexed with phosphoramidon.

Journal of molecular biology 20090109

Proteomic and phospho-proteomic profile of human platelets in basal, resting state: insights into integrin signaling.

PloS one 20090101

[Changes in the activity of amyloid-degrading metallopeptidases leads to disruption of memory in rats].

Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20090101

Role of the rat gastrointestinal mucosa in catabolism of endothelin peptides.

Regulatory peptides 20081129

The endothelin-converting enzyme-1/endothelin-1 pathway plays a critical role in inflammation-associated premature delivery in a mouse model.

The American journal of pathology 20081001

Role of endogenous endothelin-1 in post-ischemic cardiac dysfunction and norepinephrine overflow in rat hearts.

European journal of pharmacology 20080904

Preferential recruitment of neutrophils by endothelin-1 in acute lung inflammation induced by lipopolysaccharide or cigarette smoke.

International journal of chronic obstructive pulmonary disease 20080901

Effect of the putative novel selective ETA-receptor antagonist HJP272, a 1,3,6-trisubstituted-2-carboxy-quinol-4-one, on infection-mediated premature delivery.

Canadian journal of physiology and pharmacology 20080801

Human membrane metallo-endopeptidase-like protein degrades both beta-amyloid 42 and beta-amyloid 40.

Neuroscience 20080731

Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.

Journal of medicinal chemistry 20080724

Inhibition of neutral endopeptidase potentiates neutrophil activation during Mg-deficiency in the rat.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20080701

In vivo cerebrovascular effects of cocaine- and amphetamine-regulated transcript (CART) peptide.

Journal of cardiovascular pharmacology 20080701

Homology modeling and site-directed mutagenesis to identify selective inhibitors of endothelin-converting enzyme-2.

Journal of medicinal chemistry 20080626

Cysteine protease inhibitors suppress the development of tolerance to morphine antinociception.

Neuropeptides 20080601

Noxious mechanical stimulation evokes the segmental release of opioid peptides that induce mu-opioid receptor internalization in the presence of peptidase inhibitors.

Brain research 20080304

Phosphoramidon, an endothelin-converting enzyme inhibitor, attenuates lipopolysaccharide-induced acute lung injury.

Experimental lung research 20080301

Great increase in antinociceptive potency of [Leu5]enkephalin after peptidase inhibition.

Journal of pharmacological sciences 20080201

Effects of endothelin-1 1-31 on cell viabililty and [Ca2+]i in cultured neonatal rat cardiomyocytes.

Physiological research 20080101

Alzheimer disease models and human neuropathology: similarities and differences.

Acta neuropathologica 20080101

Bioinformatic analysis of the neprilysin (M13) family of peptidases reveals complex evolutionary and functional relationships.

BMC evolutionary biology 20080101

Activation of the amyloid cascade by intracerebroventricular injection of the protease inhibitor phosphoramidon.

Neuro-degenerative diseases 20080101

Activity-dependent shedding of the NMDA receptor glycine binding site by matrix metalloproteinase 3: a PUTATIVE mechanism of postsynaptic plasticity.

PloS one 20080101

A decrease in retinal progenitor cells is associated with early features of diabetic retinopathy in a model that combines diabetes and hypertension.

Molecular vision 20080101

Ozone-induced nasal hyperresponsiveness to tachykinins in guinea pigs.

American journal of rhinology 20080101

Desmoglein 2 is a substrate of kallikrein 7 in pancreatic cancer.

BMC cancer 20080101

Identifying common metalloprotease inhibitors by protein fold types using Fourier transform mass spectrometry.

Bioorganic & medicinal chemistry letters 20071201

Metabolic inactivation of the circadian transmitter, pigment dispersing factor (PDF), by neprilysin-like peptidases in Drosophila.

The Journal of experimental biology 20071201

[Ixeris sonchifolia induced vasoconstriction effect and its mechanism in rat thoracic aorta].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071201

The peptidase inhibitor CGS-26303 increases endothelin converting enzyme-1 expression in endothelial cells through accumulation of big endothelin-1.

British journal of pharmacology 20071001

Characterisation of endothelin converting enzyme-1 shedding from endothelial cells.

FEBS letters 20070918

The enhancing effects of peptidase inhibitors on the antinociceptive action of [Met5]enkephalin-Arg6-Phe7 in rats.

Journal of pharmacological sciences 20070901

Reducing amyloid plaque burden via ex vivo gene delivery of an Abeta-degrading protease: a novel therapeutic approach to Alzheimer disease.

PLoS medicine 20070801

Potentiation of bradykinin effect by angiotensin-converting enzyme inhibition does not correlate with angiotensin-converting enzyme activity in the rat mesenteric arteries.

Hypertension (Dallas, Tex. : 1979) 20070701

Expression of neutral endopeptidase (NEP/CD10) on pancreatic tumor cell lines, pancreatitis and pancreatic tumor tissues.

International journal of cancer 20070601

Cardiovascular effects of centrally applied endothelin-1 1-31 and its relationship to endothelin-1 1-21 in rats.

Autonomic neuroscience : basic & clinical 20070530

Functional evidence of des-Arg10-kallidin enzymatic inactivating pathway in isolated human umbilical vein.

Naunyn-Schmiedeberg's archives of pharmacology 20070501

Antagonism of phosphoramidon-induced antinociception in mice by mu- but not kappa-opioid receptor blockers.

Life sciences 20070417

Effect of chronic ethanol consumption on endothelin-1 generation and conversion of exogenous big-endothelin-1 by the rat carotid artery.

Alcohol (Fayetteville, N.Y.) 20070301

Neutral endopeptidase up-regulation in isolated human umbilical artery: involvement in desensitization of bradykinin-induced vasoconstrictor effects.

The Journal of pharmacology and experimental therapeutics 20070201

Expression of NEP2, a soluble neprilysin-like endopeptidase, during embryogenesis in Drosophila melanogaster.

Peptides 20070101

Central and peripheral mechanisms of narcotic antitussives: codeine-sensitive and -resistant coughs.

Cough (London, England) 20070101

Inhibition of neutral endopeptidase by thiorphan does not modify coronary vascular responses to angiotensin I, angiotensin II and bradykinin in the isolated guinea pig heart.

Pharmacological reports : PR 20070101

Big ET-1 processing into vasoactive peptides in arteries and veins.

Vascular pharmacology 20070101

Activation of the neurokinin-1 receptor by substance P triggers the release of substance P from cultured adult rat dorsal root ganglion neurons.

Molecular pain 20070101

Neprilysin protects human neuronal progenitor cells against impaired development caused by amyloid-beta peptide.

Brain research 20061208

Preparation of a protected phosphoramidon precursor via an H-phosphonate coupling strategy.

Bioorganic & medicinal chemistry letters 20061101

Effects of big endothelin-1 in comparison with endothelin-1 on the microvascular blood flow velocity and diameter of rat mesentery in vivo.

Microvascular research 20061101

Involvement of endothelial thromboxane A2 in the vasoconstrictor response induced by 15-E2t-isoprostane in isolated human umbilical vein.

Naunyn-Schmiedeberg's archives of pharmacology 20060801

Enzymatic pathways involved in the generation of endothelin-1(1-31) from exogenous big endothelin-1 in the rabbit aorta.

British journal of pharmacology 20060601

Arrhythmogenic action of endothelin-1(1-31) through conversion to endothelin-1(1-21).

Experimental biology and medicine (Maywood, N.J.) 20060601

Angiotensin converting enzyme has an inhibitory role in CGRP metabolism in human skin.

Peptides 20060401

Phosphodiesterase 5 inhibitor ameliorates renal resistance to atrial natriuretic peptide associated with obesity and hyperleptinemia.

Archives of medical research 20060401

Phosphodiesterase IV and neutral endopeptidase in airways from developing and allergen sensitized rabbits.

Pulmonary pharmacology & therapeutics 20060101

Acceleration of epithelial cell syndecan-1 shedding by anthrax hemolytic virulence factors.

BMC microbiology 20060101

Presenilin-dependent intramembrane cleavage of ephrin-B1.

Molecular neurodegeneration 20060101

beta-Amyloid degradation and Alzheimer's disease.

Journal of biomedicine & biotechnology 20060101

Blood pressure responses of endothelin-1 1-31 within the rostral ventrolateral medulla through conversion to endothelin-1 1-21.

Journal of cardiovascular pharmacology 20051201

Role of endothelin-1-dependent up-regulation of leptin in oral mucosal repair.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20051201

Endothelin-1-dependent leptin induction in gastric mucosal inflammatory responses to Helicobacter pylori lipopolysaccharide.

Biochemical and biophysical research communications 20051104

Neutral endopeptidase (EC 3.4.24.11) in cirrhotic liver: a new target to treat portal hypertension?

Journal of hepatology 20051101

Cocaine- and amphetamine-regulated transcript (CART) peptide: a vasoactive role in the cerebral circulation.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20051001

NEP inhibitors enhance C-type natriuretic peptide-induced relaxation in porcine isolated coronary artery.

Vascular pharmacology 20051001

Inhibition of neutral endopeptidase (NEP) facilitates neurogenic inflammation.

Experimental neurology 20050901

Neutral endopeptidase determines the severity of pancreatitis-associated lung injury.

The Journal of surgical research 20050901

Localization of endothelin-converting enzyme in bovine optic nerve and retina.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20050801

Up-regulation in endothelin-1 by Helicobacter pylori lipopolysaccharide interferes with gastric mucin synthesis via epidermal growth factor receptor transactivation.

Scandinavian journal of gastroenterology 20050801

The endothelin B (ETB) receptor agonist IRL 1620 is highly vasoconstrictive in two syngeneic rat tumour lines: potential for selective tumour blood flow modification.

British journal of cancer 20050711

Endothelin-1 (1-31) is an intermediate in the production of endothelin-1 after big endothelin-1 administration in vivo.

Hypertension (Dallas, Tex. : 1979) 20050701

Contribution of endogenous endothelin-1 to basal vascular tone during normal pregnancy and preeclampsia.

American journal of obstetrics and gynecology 20050701

The Kell protein of the common K2 phenotype is a catalytically active metalloprotease, whereas the rare Kell K1 antigen is inactive. Identification of novel substrates for the Kell protein.

The Journal of biological chemistry 20050603

Characterization of endothelin-converting enzyme activities in ARPE-19 cells, a human retinal pigmented epithelial cell line.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20050601

Cardiac myocytes control release of endothelin-1 in coronary vasculature.

American journal of physiology. Heart and circulatory physiology 20050501

The role of substance P and bradykinin in the cough reflex and bronchoconstriction in guinea-pigs.

European journal of pharmacology 20050418

Involvement of endothelin and nitric oxide in cyclosporine A-induced contractions in guinea pig isolated gallbladder strips.

Pharmacological research 20050301

Activation of the nociceptin/orphanin FQ receptor reduces bronchoconstriction and microvascular leakage in a rabbit model of gastroesophageal reflux.

British journal of pharmacology 20050301

Purification, characterization cloning, and sequencing of metalloendopeptidase from Streptomyces septatus TH-2.

Archives of biochemistry and biophysics 20050215

Renal responses to atrial natriuretic peptide are preserved in bilateral ureteral obstruction and augmented by neutral endopeptidase inhibition.

The Journal of urology 20050201

Endothelin-converting enzyme-1 inhibition and growth of human glioblastoma cells.

Journal of medicinal chemistry 20050127

Down-regulation does not mediate natriuretic peptide-dependent desensitization of natriuretic peptide receptor (NPR)-A or NPR-B: guanylyl cyclase-linked natriuretic peptide receptors do not internalize.

Molecular pharmacology 20050101

Effective antiprotease-antibiotic treatment of experimental anthrax.

BMC infectious diseases 20050101

Tezosentan reduces the microvascular filtration coefficient in isolated lungs from rats subjected to cecum ligation and puncture.

Critical care (London, England) 20050101

Endothelin-1-dependent up-regulation of leptin production in gastric mucosal injury by indomethacin.

Inflammopharmacology 20050101

Long-lasting smooth-muscle relaxation by a novel PACAP analogue in human bronchi.

Regulatory peptides 20041215

Further evidence on the anxiogenic-like effect of substance P evaluated in the elevated plus-maze in rats.

Behavioural brain research 20041005

Specificity comparison of a serine endopeptidase (SH1) and a serine thiol endopeptidase (STH2) purified from human urine.

The international journal of biochemistry & cell biology 20041001

Despite minimal hemodynamic alterations endotoxemia modulates NOS and p38-MAPK phosphorylation via metalloendopeptidases.

Molecular and cellular biochemistry 20041001

Porphyromonas gingivalis lipopolysaccharide-induced up-regulation in endothelin-1 interferes with salivary mucin synthesis via epidermal growth factor receptor transactivation.

IUBMB life 20041001

Interleukin-1beta attenuates endothelin B receptor-mediated airway contractions in a murine in vitro model of asthma: roles of endothelin converting enzyme and mitogen-activated protein kinase pathways.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040901

[Physiological and pathophysiological roles of the endothelin converting enzymes].

Nihon rinsho. Japanese journal of clinical medicine 20040901

Involvement of MAP-kinase, PI3-kinase and EGF-receptor in the stimulatory effect of Neurotensin on DNA synthesis in PC3 cells.

Regulatory peptides 20040815

Degradation of pulmonary surfactant protein D by Pseudomonas aeruginosa elastase abrogates innate immune function.

The Journal of biological chemistry 20040716

Obligatory role for endogenous endothelin in mediating the hypertrophic effects of phenylephrine and angiotensin II in neonatal rat ventricular myocytes: evidence for two distinct mechanisms for endothelin regulation.

The Journal of pharmacology and experimental therapeutics 20040701

Hypoxia augments TNF-alpha-mediated endothelin-1 release and cell proliferation in human optic nerve head astrocytes.

Biochemical and biophysical research communications 20040604

Endothelins and their inhibition in the human skin microcirculation: ET[1-31], a new vasoconstrictor peptide.

British journal of clinical pharmacology 20040601

Endothelin-induced constriction of the ductus venosus in fetal sheep: developmental aspects and possible interaction with vasodilatory prostaglandin.

British journal of pharmacology 20040601

[Endothelin].

Nihon rinsho. Japanese journal of clinical medicine 20040601

A continuous spectrophotometric assay for Pseudomonas aeruginosa LasA protease (staphylolysin) using a two-stage enzymatic reaction.

Analytical biochemistry 20040515

Occurrence of substance P(1-7) in the metabolism of substance P and its antinociceptive activity at the mouse spinal cord level.

Methods and findings in experimental and clinical pharmacology 20040401

Nociceptin inhibits airway microvascular leakage induced by HCl intra-oesophageal instillation.

British journal of pharmacology 20040301

The effect of phosphoramidon on inflammation-mediated preterm delivery in a mouse model.

American journal of obstetrics and gynecology 20040201

Signal pathway involved in increased expression of neutral endopeptidase 24.11 by gonadotropin releasing hormone in choriocarcinoma cells.

Placenta 20040101

Liver-specific expression of the agouti gene in transgenic mice promotes liver carcinogenesis in the absence of obesity and diabetes.

Molecular cancer 20040101

[The new class of drugs-- metalloprotease inhibitors -- in the treatment of heart failure].

Klinicheskaia meditsina 20040101

Essential role for vascular gelatinase activity in relaxin-induced renal vasodilation, hyperfiltration, and reduced myogenic reactivity of small arteries.

Circulation research 20031212

A low dose of angiotensin II increases inotropism through activation of reverse Na(+)/Ca(2+) exchange by endothelin release.

Cardiovascular research 20031201

[Protective effects of phosphoramidon on the experimental myocardial injury in rats].

Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 20031201

Active amino acids of the Kell blood group protein and model of the ectodomain based on the structure of neutral endopeptidase 24.11.

Blood 20031015

Aminopeptidases function as endocytic receptors in the trophotaenial placenta of the goodeid fish, Ameca splendens (Teleostei: Atheriniformes).

Journal of experimental zoology. Part A, Comparative experimental biology 20031001

Metalloendopeptidase inhibition regulates phosphorylation of p38-mitogen-activated protein kinase and nitric oxide synthase in heart after endotoxemia.

Shock (Augusta, Ga.) 20031001

The role of endothelin converting enzyme inhibition during group B streptococcus-induced pulmonary hypertension in newborn piglets.

Pediatric research 20030901

CD10 is a key enzyme involved in the activation of tumor-activated peptide prodrug CPI-0004Na and novel analogues: implications for the design of novel peptide prodrugs for the therapy of CD10+ tumors.

Cancer research 20030901

Cerebral angiogenesis and expression of VEGF after subarachnoid hemorrhage (SAH) in rats.

Brain research 20030815

Isolation and characterization of a zinc-containing metalloprotease expressed by Vibrio tubiashii.

Canadian journal of microbiology 20030801

The effects of phosphoramidon on the expression of human endothelin-converting enzyme-1 (ECE-1) isoforms.

Journal of cardiovascular pharmacology 20030701

Crucial role of extracellular signal-regulated kinase pathway in reactive oxygen species-mediated endothelin-1 gene expression induced by endothelin-1 in rat cardiac fibroblasts.

Molecular pharmacology 20030501

Pathways and kinetics of deslorelin degradation in an airway epithelial cell line (Calu-1).

Pharmaceutical research 20030501

[D-Val22]big ET-1[16-38] inhibits endothelin-converting enzyme activity: a promising concept in the prevention of cerebral vasospasm.

Neurosurgical review 20030501

Pseudomonas aeruginosa elastase degrades surfactant proteins A and D.

American journal of respiratory cell and molecular biology 20030401

Vasospasm following subarachnoid hemorrhage: evidence against functional upregulation of protein kinase C constrictor pathway.

Neurological research 20030401

Binding of a new bioactive 31-amino-acid endothelin-1 to an endothelin ET(B) or ET(B)-like receptor in porcine lungs.

European journal of pharmacology 20030328

Peptidases prevent mu-opioid receptor internalization in dorsal horn neurons by endogenously released opioids.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20030301

The formyl peptide N-formyl-methionyl-leucyl-phenylalanine downregulates the expression of FcgammaRs in interferon-gamma-activated monocytes/macrophages in vitro and in vivo.

Scandinavian journal of immunology 20030301

Identification and localization of a neprilysin-like activity that degrades tachykinin-related peptides in the brain of the cockroach, Leucophaea maderae, and locust, Locusta migratoria.

The Journal of comparative neurology 20030224

Effects of kinins on mammalian spermatozoa and the impact of peptidolytic enzymes.

Andrologia 20030201

Effect of endothelin-1 (1-31) on the renal resistance vessels.

The journal of medical investigation : JMI 20030201

Role of tachykinins in the bronchoconstriction induced by HCl intraesophageal instillation in the rabbit.

Life sciences 20030124

Action of three ectopeptidases on corticotropin-releasing factor: metabolism and functional aspects.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030101

Attenuation of renal ischemia/reperfusion injury by a triple drug combination therapy.

Journal of nephrology 20030101

Mechanical stretch-induced mitogen-activated protein kinase activation is mediated via angiotensin and endothelin systems in vascular smooth muscle cells.

Biological & pharmaceutical bulletin 20021201

High-performance liquid chromatographic separation of renin-angiotensin system peptides and most of their metabolic fragments.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20021125

Role of abnormal neutral endopeptidase-like activities in Hyp mouse bone cells in renal phosphate transport.

American journal of physiology. Cell physiology 20021101

Cardioprotective effects of phosphoramidon on myocardial structure and function in murine Chagas' disease.

International journal for parasitology 20021101

The mechanisms for tachykinin-induced contractions of the rabbit corpus cavernosum.

British journal of pharmacology 20021101

Extracellular peptidases of imaginal discs of Drosophila melanogaster.

Peptides 20021101

Effect of endothelin-converting enzyme inhibitors on big endothelin-1 induced contraction in isolated rat basilar artery.

Acta neurochirurgica 20021101

Combination therapy of N-acetylcysteine, sodium nitroprusside and phosphoramidon attenuates ischemia-reperfusion injury in rat kidney.

Molecular and cellular biochemistry 20021101

Attenuation of ischemia/reperfusion induced MAP kinases by N-acetyl cysteine, sodium nitroprusside and phosphoramidon.

Molecular and cellular biochemistry 20021101

[Met5]enkephalin-Arg-Gly-Leu-induced antinociception is greatly increased by peptidase inhibitors.

European journal of pharmacology 20021018

The increased proliferation of cultured neuroblastoma cells treated with vasoactive intestinal peptide is enhanced by simultaneous inhibition of neutral endopeptidase.

Regulatory peptides 20021015

Degradation of nociceptin (orphanin FQ) by mouse spinal cord synaptic membranes is triggered by endopeptidase-24.11: an in vitro and in vivo study.

Biochemical pharmacology 20021015

Bradykinin potentiation by ACE inhibitors: a matter of metabolism.

British journal of pharmacology 20020901

Effect of quercetin on plasma extravasation in rat CNS and dura mater by ACE and NEP inhibition.

Phytotherapy research : PTR 20020901

Effect of glycerol on endothelium-derived factors in the vasculature of the rabbit kidney.

Clinical and experimental pharmacology & physiology 20020801

Endothelin-converting enzyme activity in human cerebral circulation.

Neurosurgery 20020801

Characterization of PgPepO, a bacterial homologue of endothelin-converting enzyme-1.

Clinical science (London, England : 1979) 20020801

Expression, purification and characterization of the monomeric and dimeric forms of soluble bovine endothelin converting enzyme-1a.

Clinical science (London, England : 1979) 20020801

Phosphoramidon treatment improves the consequences of chagasic heart disease in mice.

Clinical science (London, England : 1979) 20020801

Tachykinins and airway microvascular leakage induced by HCl intra-oesophageal instillation.

The European respiratory journal 20020801

Induction of apoptosis and CD10/neutral endopeptidase expression by jaspamide in HL-60 line cells.

Cellular and molecular life sciences : CMLS 20020801

Pressor and pulmonary responses to ET-1(1-31) in guinea-pigs.

British journal of pharmacology 20020701

Possible involvement of placental peptidases that degrade gonadotropin-releasing hormone (GnRH) in the dynamic pattern of placental hCG secretion via GnRH degradation.

Placenta 20020701

Vasospasm following subarachnoid hemorrhage: evidence against functional upregulation of Rho kinase constrictor pathway.

Neurological research 20020601

Efficient transesterification of sucrose catalysed by the metalloprotease thermolysin in dimethylsulfoxide.

FEBS letters 20020522

Inhibition of endothelin-1 improves survival and vasculopathy in rat cardiac transplants treated with cyclosporine.

Transplantation 20020415

Inactivation of a tachykinin-related peptide: identification of four neuropeptide-degrading enzymes in neuronal membranes of insects from four different orders.

Peptides 20020401

Substance P induced preprotachykinin-a mRNA, neutral endopeptidase mRNA and substance P in cultured normal fibroblasts.

International archives of allergy and immunology 20020401

Enhancement of neurokinin A-induced smooth muscle contraction in human urinary bladder by mucosal removal and phosphoramidon: relationship to peptidase inhibition.

European journal of pharmacology 20020308

ET(A) and ET(B) receptors modulate the proliferation of human pulmonary artery smooth muscle cells.

American journal of respiratory and critical care medicine 20020201

Neprilysin inhibitors potentiate effects of bradykinin on b2 receptor.

Hypertension (Dallas, Tex. : 1979) 20020201

Endothelin-1[1-31]: a novel autocrine-paracrine regulator of human adrenal cortex secretion and growth.

The Journal of clinical endocrinology and metabolism 20020101

Endothelin-converting enzyme activity in vascular smooth muscle preparations in vitro.

Methods in molecular biology (Clifton, N.J.) 20020101

Mycosin-1, a subtilisin-like serine protease of Mycobacterium tuberculosis, is cell wall-associated and expressed during infection of macrophages.

BMC microbiology 20020101

Vascular endothelin converting enzyme-1 expression and activity is upregulated in clinical diabetes.

Ethnicity & disease 20020101

Zinc and Manduca sexta hemocyte functions.

Journal of insect science (Online) 20020101

Abstracts of the Fourth International Symposium on Molecular Insect Science. May 28-June 2, 2002. Tucson, Arizona, USA.

Journal of insect science (Online) 20020101

Tachykinin NK(3) receptor agonists induced microvascular leakage hypersensitivity in the guinea-pig airways.

European journal of pharmacology 20011221

Soluble recombinant neprilysin induces aggrecanase-mediated cleavage of aggrecan in cartilage explant cultures.

Archives of biochemistry and biophysics 20011215

The role of substance P release in the lung with esophageal acid.

The American journal of medicine 20011203

Effect of neutral endopeptidase inhibitor on bradykinin-induced bronchoconstriction.

Life sciences 20011121

Relaxation and modulation of cyclic AMP production in response to atrial natriuretic peptides in guinea pig tracheal smooth muscle.

European journal of pharmacology 20011102

Vasoconstrictor activity of novel endothelin peptide, ET-1(1 - 31), in human mammary and coronary arteries in vitro.

British journal of pharmacology 20011101

In vitro contractile effects of neurokinin receptor blockade in the human ureter.

The Journal of urology 20011001

Differential effects of U46619 on renal regional hemodynamics in the rat: involvement of endothelin.

The Journal of pharmacology and experimental therapeutics 20011001

Determination of bradykinin in rat urine by coupled-column high pressure liquid chromatography with precolumn derivatization with a water-soluble fluorogenic reagent.

Analytical biochemistry 20011001

Roles of mast cells and sensory nerves in cutaneous vascular hyperpermeability and scratching behavior induced by poly-L-arginine in rats.

European journal of pharmacology 20010817

A proteinase inhibitor decreases tumor growth in a laparoscopic rat model.

Surgical endoscopy 20010801

Deletion of neutral endopeptidase exacerbates intestinal inflammation induced by Clostridium difficile toxin A.

American journal of physiology. Gastrointestinal and liver physiology 20010801

Changes in the expression of tachykinin receptors in the rat uterus during the course of pregnancy.

Biology of reproduction 20010801

Effect of quercetin on tachykinin-induced plasma extravasation in rat urinary bladder.

Phytotherapy research : PTR 20010801

Immune complexes (IC) down-regulate the basal and interferon-gamma-induced expression of MHC class II on human monocytes.

Clinical and experimental immunology 20010801

Apparent B-type natriuretic peptide selectivity in the kidney due to differential processing.

Canadian journal of physiology and pharmacology 20010801

Degradation of the Alzheimer's amyloid beta peptide by endothelin-converting enzyme.

The Journal of biological chemistry 20010706

Bradykinin augments fibroblast-mediated contraction of released collagen gels.

American journal of physiology. Lung cellular and molecular physiology 20010701

Upregulation of neutral endopeptidase expression and enzymatic activity during the differentiation of human choriocarcinoma cells.

Placenta 20010701

Endogenously released endothelin-1 from human pulmonary artery smooth muscle promotes cellular proliferation: relevance to pathogenesis of pulmonary hypertension and vascular remodeling.

American journal of respiratory cell and molecular biology 20010701

Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases.

The Journal of biological chemistry 20010615

Soluble CD44 inhibits melanoma tumor growth by blocking cell surface CD44 binding to hyaluronic acid.

Oncogene 20010607

Tachykinin-induced bronchoconstriction in sheep is NK-1 receptor mediated and exhibits tachyphylaxis.

Respirology (Carlton, Vic.) 20010601

Effect of ECE and NEP inhibition on cigarette smoke-induced cell proliferation in the rat lung.

Inhalation toxicology 20010601

Purification and characterization of a 43.5 kDa keratinolytic metalloprotease from Microsporum canis.

Medical mycology 20010601

Endothelium-dependent relaxation in response to low concentrations of bradykinin is enhanced by phosphoramidon, bosentan and BQ-123 in bovine coronary arteries in vitro.

Japanese journal of pharmacology 20010601

Airway hyperresponsiveness to bronchoconstrictor challenge after wood smoke exposure in guinea pigs.

Life sciences 20010518

The role of endothelin in the pathogenesis of Chagas' disease.

International journal for parasitology 20010501

Pulmonary adrenomedullin counteracts deterioration of coronary flow and myocardial performance evoked by pulmonary endothelins in experimental acute respiratory distress syndrome.

Critical care medicine 20010501

The lungs as an anti-inflammatory organ of the body.

Critical care medicine 20010501

A three-dimensional model of endothelin-converting enzyme (ECE) based on the X-ray structure of neutral endopeptidase 24.11 (NEP).

Protein engineering 20010501

Isoprostaglandin E2 type-III (8-iso-prostaglandin E2) evoked contractions in the human internal mammary artery.

Life sciences 20010413

Mechanisms underlying increased release of endothelin-1 from aorta in diabetic rats.

Peptides 20010401

Phosphoramidon-sensitive endothelin-converting enzymes modulate cerebral blood flow and neural damage of hypoxic rats.

Neuroscience letters 20010330

Reverse mode of the Na+-Ca2+ exchange after myocardial stretch: underlying mechanism of the slow force response.

Circulation research 20010302

The neprilysin (NEP) family of zinc metalloendopeptidases: genomics and function.

BioEssays : news and reviews in molecular, cellular and developmental biology 20010301

Interactions of human matrix metalloproteinase 7 (matrilysin) with the inhibitors thiorphan and R-94138.

Journal of biochemistry 20010301

Characterization of increased cough sensitivity after antigen challenge in guinea pigs.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20010301

Antinociceptive effect produced by intracerebroventricularly administered dynorphin A is potentiated by p-hydroxymercuribenzoate or phosphoramidon in the mouse formalin test.

Brain research 20010209

Chronic tobacco smoke exposure increases airway sensitivity to capsaicin in awake guinea pigs.

Journal of applied physiology (Bethesda, Md. : 1985) 20010201

Neutral endopeptidase terminates substance P-induced inflammation in allergic contact dermatitis.

Journal of immunology (Baltimore, Md. : 1950) 20010115

Mitogen-activated protein kinase activity regulation role of angiotensin and endothelin systems in vascular smooth muscle cells.

European journal of pharmacology 20010105

NK2 tachykinin receptors mediate contraction of the pig intravesical ureter: tachykinin-induced enhancement of non-adrenergic non-cholinergic excitatory neurotransmission.

Neurourology and urodynamics 20010101

Effect of phosphoramidon on brain tissue angiogenesis in the chronic phase of vasospasm after subarachnoid hemorrhage in the rat.

Medical science monitor : international medical journal of experimental and clinical research 20010101

Role of endothelin-converting enzyme-1 in the suppression of constitutive nitric oxide synthase in rat gastric mucosal injury by indomethacin.

Scandinavian journal of gastroenterology 20001101

Pharmacological characterization of a novel sulfonylureid-pyrazole derivative, SM-19712, a potent nonpeptidic inhibitor of endothelin converting enzyme.

Japanese journal of pharmacology 20000901

Potent and selective non-peptidic inhibitors of endothelin-converting enzyme-1 with sustained duration of action.

Journal of medicinal chemistry 20000210

Morphine preconditioning attenuates neutrophil activation in rat models of myocardial infarction.

Cardiovascular research 19981201

Acute and chronic effects of capsaicin in perfused rat muscle: the role of tachykinins and calcitonin gene-related peptide.

The Journal of pharmacology and experimental therapeutics 19981101

Influence of several peptidase inhibitors on the pro-inflammatory effects of substance P, capsaicin and collagenase.

Naunyn-Schmiedeberg's archives of pharmacology 19961101

In vitro metabolism of an insect neuropeptide by neural membrane preparations from Lymantria dispar.

Peptides 19960101

Regulation of N-formyl-methionyl-leucyl-phenylalanine receptor recycling by surface membrane neutral endopeptidase-mediated degradation of ligand.

Journal of leukocyte biology 19951001

Brain cathepsin B but not metalloendopeptidases degrade rAPP751 with production of amyloidogenic fragments. Comparison with synthetic peptides emulating beta- and gamma-secretase sites.

International journal of peptide and protein research 19950101

Purification and characterization of a neutral zinc endopeptidase secreted by Flavobacterium meningosepticum.

Archives of biochemistry and biophysics 19940515

Profile of capsaicin-induced mouse ear oedema as neurogenic inflammatory model: comparison with arachidonic acid-induced ear oedema.

British journal of pharmacology 19931201

Degradation of bradykinin by neutral endopeptidase (EC 3.4.24.11) in cultured human endothelial cells.

European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies 19930501

Jurkat T cells express a functional neutral endopeptidase activity (CALLA) involved in T cell activation.

The EMBO journal 19921101

Functional reactivity of different central opioid receptor systems following clomipramine treatments.

Pharmacological research 19900101

Neuropeptide-degrading endopeptidase activity of locust (Schistocerca gregaria) synaptic membranes.

The Biochemical journal 19881101

Effects of bestatin and phosphoramidon on the hypertensive response to physostigmine in the rat.

Fundamental & clinical pharmacology 19870101

Enkephalinase inhibition suppresses naloxone-induced jumping in morphine-dependent mice.

Archives internationales de pharmacodynamie et de therapie 19861001

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