200,000+ products from a single source!

sales@angenechem.com

Home > Thiazole > 31883-05-3

31883-05-3

31883-05-3 | CARBAMIC ACID, [10-[3-(4-MORPHOLINYL)-1-OXOPROPYL]-10H-PHENOTHIAZIN-2-YL]-, ETHYL ESTER

CAS No: 31883-05-3 Catalog No: AG00BXKQ MDL No:

Product Description

Catalog Number:
AG00BXKQ
Chemical Name:
CARBAMIC ACID, [10-[3-(4-MORPHOLINYL)-1-OXOPROPYL]-10H-PHENOTHIAZIN-2-YL]-, ETHYL ESTER
CAS Number:
31883-05-3
Molecular Formula:
C22H25N3O4S
Molecular Weight:
427.5166
IUPAC Name:
ethyl N-[10-(3-morpholin-4-ylpropanoyl)phenothiazin-2-yl]carbamate
InChI:
InChI=1S/C22H25N3O4S/c1-2-29-22(27)23-16-7-8-20-18(15-16)25(17-5-3-4-6-19(17)30-20)21(26)9-10-24-11-13-28-14-12-24/h3-8,15H,2,9-14H2,1H3,(H,23,27)
InChI Key:
FUBVWMNBEHXPSU-UHFFFAOYSA-N
SMILES:
CCOC(=O)Nc1ccc2c(c1)N(C(=O)CCN1CCOCC1)c1c(S2)cccc1
EC Number:
250-854-5
UNII:
2GT1D0TMX1

Properties

Complexity:
601  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
427.157g/mol
Formal Charge:
0
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
427.519g/mol
Monoisotopic Mass:
427.157g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
96.4A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3  

Literature

Title Journal
Medical reversal: why we must raise the bar before adopting new technologies. The Yale journal of biology and medicine 20111201
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS computational biology 20111201
Atrial fibrillation and the use of oral bisphosphonates. Therapeutics and clinical risk management 20110101
[Appearance of ECG signs of the Brugada syndrome during therapy with class 1C antiarrhythmic drug ethacizine]. Kardiologiia 20110101
Depression in vascular pathologies: the neurologist's point of view. Vascular health and risk management 20110101
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. Bioorganic & medicinal chemistry letters 20101101
Development of a cell-based high-throughput assay to screen for inhibitors of organic anion transporting polypeptides 1B1 and 1B3. Current chemical genomics 20100101
Bayes' Theorem to estimate population prevalence from Alcohol Use Disorders Identification Test (AUDIT) scores. Addiction (Abingdon, England) 20090701
Comparison of immortalized Fa2N-4 cells and human hepatocytes as in vitro models for cytochrome P450 induction. Drug metabolism and disposition: the biological fate of chemicals 20080601
Effect of drugs on defibrillation capacity. Drugs 20080101
[Immunochemical properties of conjugated antigens from N-substituted phenothiazines and dibenzazepines with antiarrhythmic activity]. Prikladnaia biokhimiia i mikrobiologiia 20080101
[The role of reflexotherapy and physical training in the combined treatment and the prevention of paroxysmal form of idiopathic atrial fibrillation]. Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury 20080101
Steroids in late ARDS? Critical care (London, England) 20070101
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Prediction of genotoxicity of chemical compounds by statistical learning methods. Chemical research in toxicology 20050601
Chiropractic as spine care: a model for the profession. Chiropractic & osteopathy 20050101
Non-linear heart rate variability and risk stratification in cardiovascular disease. Indian pacing and electrophysiology journal 20050101
Rate-control or rhythm-control: where do we stand? Indian pacing and electrophysiology journal 20050101
[Effect of etmosin on biliary motility disorders in patients with ischemic heart disease]. Likars'ka sprava 20040101
[Moricizine in treatment of one case with tachycardia-induced cardiomyopathy]. Zhonghua er ke za zhi = Chinese journal of pediatrics 20031001
Moricizine induced increase in pacing threshold. Pacing and clinical electrophysiology : PACE 20030101
Moricizine, an antiarrhythmic agent, as a potent inhibitor of hepatic microsomal CYP1A. Pharmacology 20021201
Analysis of moricizine block of sodium current in isolated guinea-pig atrial myocytes. Atrioventricular difference of moricizine block. Vascular pharmacology 20020301
Efficacy and safety of moricizine in the maintenance of sinus rhythm in patients with recurrent atrial fibrillation. The American journal of cardiology 20010115
[Mechanisms of action of hypersodium medium on contractile activity of isolated rat heart]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20010101
Action of MgSO4 differs from moricizine and verapamil on ouabain-induced ventricular tachycardia in normomagnesemic conscious dogs. Journal of cardiovascular pharmacology 19940201
Effects of magnesium and ethmozin on ventricular tachycardia induced by ouabain and ventricular pacing in conscious dogs with complete atrioventricular block. Acta physiologica Hungarica 19930101
Moricizine-induced proarrhythmia. Clinical cardiology 19921101
Exercise induced fatal sinusoidal ventricular tachycardia secondary to moricizine. Pacing and clinical electrophysiology : PACE 19921001
The prevalence of proarrhythmic events during moricizine therapy and their relationship to ventricular function. American heart journal 19921001
Proarrhythmia in patients treated with moricizine. Pacing and clinical electrophysiology : PACE 19920901
Effects of advancing age on the efficacy and side effects of antiarrhythmic drugs in post-myocardial infarction patients with ventricular arrhythmias. The CAST Investigators. Journal of the American Geriatrics Society 19920701
Electrophysiologic response to moricizine in patients with sustained ventricular arrhythmias. Annals of internal medicine 19920301
Exacerbation of congestive heart failure secondary to moricizine. Pharmacotherapy 19920101
Increased risk of death and cardiac arrest from encainide and flecainide in patients after non-Q-wave acute myocardial infarction in the Cardiac Arrhythmia Suppression Trial. CAST Investigators. The American journal of cardiology 19911215
A cerebral computed tomography study of patients with drug-induced psychoses. European archives of psychiatry and clinical neuroscience 19910101
Proarrhythmic potential of moricizine: strengths and limitations of a data base analysis. The American journal of cardiology 19900220
Congestive heart failure induced by six of the newer antiarrhythmic drugs. Journal of the American College of Cardiology 19891101
[Comparative study of the activity of anti-arrhythmia agents in calcium chloride-induced arrhythmia in mice]. Farmakologiia i toksikologiia 19830101
New drugs for treating cardiac arrhythmias. Postgraduate medicine 19810101

Related Products

© 2019 Angene International Limited. All rights Reserved.