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30538-92-2 | Decanedioic acid, 1,10-bis(1-hydroxy-2,2,6,6-tetramethyl-4-piperidinyl) ester
CAS No: 30538-92-2 Catalog No: AG0030HP MDL No:
Product Description
Catalog Number:
AG0030HP
Chemical Name:
Decanedioic acid, 1,10-bis(1-hydroxy-2,2,6,6-tetramethyl-4-piperidinyl) ester
CAS Number:
30538-92-2
Molecular Formula:
C28H52N2O6
Molecular Weight:
512.7223
IUPAC Name:
bis(1-hydroxy-2,2,6,6-tetramethylpiperidin-4-yl) decanedioate
InChI:
InChI=1S/C28H52N2O6/c1-25(2)17-21(18-26(3,4)29(25)33)35-23(31)15-13-11-9-10-12-14-16-24(32)36-22-19-27(5,6)30(34)28(7,8)20-22/h21-22,33-34H,9-20H2,1-8H3
InChI Key:
SXPLGYBFGPYAHS-UHFFFAOYSA-N
SMILES:
ON1C(C)(C)CC(CC1(C)C)OC(=O)CCCCCCCCC(=O)OC1CC(C)(C)N(C(C1)(C)C)O
UNII:
19R5N3WR4N
Properties
Complexity:
650
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
512.383g/mol
Formal Charge:
0
Heavy Atom Count:
36
Hydrogen Bond Acceptor Count:
8
Hydrogen Bond Donor Count:
2
Isotope Atom Count:
0
Molecular Weight:
512.732g/mol
Monoisotopic Mass:
512.383g/mol
Rotatable Bond Count:
13
Topological Polar Surface Area:
99.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
5.4
Literature
| Title | Journal |
|---|---|
| Anti-inflammatory activity of the non-peptidyl low molecular weight radical scavenger IAC in carrageenan-induced oedema in rats. | The Journal of pharmacy and pharmacology 20110301 |
| The radical scavenger IAC (bis(1-hydroxy-2,2,6,6-tetramethyl-4-piperidinyl) decantionate) decreases mortality, enhances cognitive functions in water maze and reduces amyloid plaque burden in hAβPP transgenic mice. | Journal of Alzheimer's disease : JAD 20110101 |
| Further evidence of the antiulcer activity of IAC, a novel free radical scavenger. | Pharmacology 20110101 |
| Non-peptidyl low molecular weight radical scavenger IAC attenuates DSS-induced colitis in rats. | World journal of gastroenterology 20100807 |
| Persistent correction of hyperglycemia in streptozotocin-nicotinamide-induced diabetic mice by a non-conventional radical scavenger. | Naunyn-Schmiedeberg's archives of pharmacology 20100801 |
| The novel radical scavenger IAC is effective in preventing and protecting against post-ischemic brain damage in Mongolian gerbils. | Journal of the neurological sciences 20100315 |
| Effects of the novel non-peptidyl low molecular weight radical scavenger IAC in different models of inflammation: a new perspective in anti- inflammatory therapy. | Current medicinal chemistry 20100101 |
| The non-peptidyl low molecular weight radical scavenger IAC protects human pancreatic islets from lipotoxicity. | Molecular and cellular endocrinology 20091015 |
| Effects of the non-peptidyl low molecular weight radical scavenger IAC in DNBS-induced colitis in rats. | European journal of pharmacology 20090701 |
| Anti-ulcer activity of IAC, a novel free-radical scavenger, in rats. | The Journal of pharmacy and pharmacology 20090301 |
| Neuroprotective properties of the non-peptidyl radical scavenger IAC in rats following transient focal cerebral ischemia. | Brain research 20080501 |
| Beneficial effect of the nonpeptidyl low molecular weight radical scavenger IAC on cultured human islet function. | Cell transplantation 20080101 |
| Reduction of oxidative stress by a new low-molecular-weight antioxidant improves metabolic alterations in a nonobese mouse diabetes model. | Pancreas 20071101 |
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