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305-62-4

305-62-4 | Butanoic acid, 2,4-diamino-

CAS No: 305-62-4 Catalog No: AG0030DR MDL No:MFCD00025612

Product Description

Catalog Number:
AG0030DR
Chemical Name:
Butanoic acid, 2,4-diamino-
CAS Number:
305-62-4
Molecular Formula:
C4H10N2O2
Molecular Weight:
118.1344
MDL Number:
MFCD00025612
IUPAC Name:
2,4-diaminobutanoic acid
InChI:
InChI=1S/C4H10N2O2/c5-2-1-3(6)4(7)8/h3H,1-2,5-6H2,(H,7,8)
InChI Key:
OGNSCSPNOLGXSM-UHFFFAOYSA-N
SMILES:
NC(C(=O)O)CCN
EC Number:
206-166-2

Properties

Complexity:
84.1  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
118.074g/mol
Formal Charge:
0
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
118.136g/mol
Monoisotopic Mass:
118.074g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
89.3A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
XLogP3:
-4.6  

Literature

Title Journal
Involvement of GABAergic and glutamatergic systems in the anticonvulsant activity of 3-alkynyl selenophene in 21 day-old rats. Molecular and cellular biochemistry 20120601
Elucidation of matrix effects and performance of solid-phase extraction for LC-MS/MS analysis of β-N-methylamino-L-alanine (BMAA) and 2,4-diaminobutyric acid (DAB) neurotoxins in cyanobacteria. The Analyst 20120307
Leucobacter denitrificans sp. nov., isolated from cow dung. Journal of microbiology (Seoul, Korea) 20120201
In silico insights into the symbiotic nitrogen fixation in Sinorhizobium meliloti via metabolic reconstruction. PloS one 20120101
Paenibacillus polymyxa PKB1 produces variants of polymyxin B-type antibiotics. Chemistry & biology 20111223
Lipophilic Pt(II) complexes with selective efficacy against cisplatin-resistant testicular cancer cells. Journal of inorganic biochemistry 20111201
Leucobacter kyeonggiensis sp. nov., a new species isolated from dye waste water. Journal of microbiology (Seoul, Korea) 20111201
Discovery of α,β- and α,γ-diamino acid scaffolds for the inhibition of M1 family aminopeptidases. ChemMedChem 20111104
Cryobacterium arcticum sp. nov., a psychrotolerant bacterium from an Arctic soil. International journal of systematic and evolutionary microbiology 20110801
Leucobacter salsicius sp. nov., from a salt-fermented food. International journal of systematic and evolutionary microbiology 20110301
Amnibacterium kyonggiense gen. nov., sp. nov., a new member of the family Microbacteriaceae. International journal of systematic and evolutionary microbiology 20110101
Prominent human health impacts from several marine microbes: history, ecology, and public health implications. International journal of microbiology 20110101
Genome-scale reconstruction of metabolic network for a halophilic extremophile, Chromohalobacter salexigens DSM 3043. BMC systems biology 20110101
Evaluation of salt tolerance in ectoine-transgenic tomato plants (Lycopersicon esculentum) in terms of photosynthesis, osmotic adjustment, and carbon partitioning. GM crops 20110101
Mutation of L-2,3-diaminopropionic acid synthase genes blocks staphyloferrin B synthesis in Staphylococcus aureus. BMC microbiology 20110101
Leucobacter aerolatus sp. nov., from the air of a duck barn. International journal of systematic and evolutionary microbiology 20101201
The cyanobacteria derived toxin Beta-N-methylamino-L-alanine and amyotrophic lateral sclerosis. Toxins 20101201
Diphenyl diselenide-induced seizures in rat pups: possible interaction with GABAergic system. Neurological research 20101101
Distinguishing the cyanobacterial neurotoxin beta-N-methylamino-L-alanine (BMAA) from its structural isomer 2,4-diaminobutyric acid (2,4-DAB). Toxicon : official journal of the International Society on Toxinology 20101101
Localization of a GABA transporter to glial cells in the developing and adult olfactory pathway of the moth Manduca sexta. The Journal of comparative neurology 20100315
Diastereo- and enantioselective synthesis of alpha,gamma-diaminobutyric acid derivatives via Cu-catalyzed asymmetric Michael reaction. Organic letters 20100305
LC-MS/MS determination of the isomeric neurotoxins BMAA (beta-N-methylamino-L-alanine) and DAB (2,4-diaminobutyric acid) in cyanobacteria and seeds of Cycas revoluta and Lathyrus latifolius. Toxicon : official journal of the International Society on Toxinology 20100101
Leifsonia lichenia sp. nov., isolated from lichen in Japan. The Journal of general and applied microbiology 20091001
Analysis of achromobactin biosynthesis by Pseudomonas syringae pv. syringae B728a. Journal of bacteriology 20090701
An alternative polyamine biosynthetic pathway is widespread in bacteria and essential for biofilm formation in Vibrio cholerae. The Journal of biological chemistry 20090410
N-Terminal 2,3-diaminopropionic acid (Dap) peptides as efficient methylglyoxal scavengers to inhibit advanced glycation endproduct (AGE) formation. Bioorganic & medicinal chemistry 20090315
Contribution of each amino acid residue in polymyxin B(3) to antimicrobial and lipopolysaccharide binding activity. Chemical & pharmaceutical bulletin 20090301
Colistin and polymyxin B: a re-emergence. Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine 20090101
Determination of the neurotoxins BMAA (beta-N-methylamino-L-alanine) and DAB (alpha-,gamma-diaminobutyric acid) by LC-MSMS in Dutch urban waters with cyanobacterial blooms. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20090101
Presence of the neurotoxic amino acids beta-N-methylamino-L-alanine (BMAA) and 2,4-diamino-butyric acid (DAB) in shallow springs from the Gobi Desert. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20090101
Cyanobacteria and BMAA exposure from desert dust: a possible link to sporadic ALS among Gulf War veterans. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20090101
m-Trifluoromethyl-diphenyl diselenide attenuates pentylenetetrazole-induced seizures in mice by inhibiting GABA uptake in cerebral cortex slices. Pharmacological reports : PR 20090101
Mechanism of radical-based catalysis in the reaction catalyzed by adenosylcobalamin-dependent ornithine 4,5-aminomutase. The Journal of biological chemistry 20081212
Leucobacter tardus sp. nov., isolated from the phyllosphere of Solanum tuberosum L. International journal of systematic and evolutionary microbiology 20081101
Leifsonia pindariensis sp. nov., isolated from the Pindari glacier of the Indian Himalayas, and emended description of the genus Leifsonia. International journal of systematic and evolutionary microbiology 20080901
Leifsonia bigeumensis sp. nov., isolated from soil on Bigeum Island, Korea. International journal of systematic and evolutionary microbiology 20080801
Terpene conjugates of diaminedichloridoplatinum(II) complexes: antiproliferative effects in HL-60 leukemia, 518A2 melanoma, and HT-29 colon cancer cells. Chemistry & biodiversity 20080801
Heterologous ectoine production in Escherichia coli: by-passing the metabolic bottle-neck. Saline systems 20080101
Unravelling the adaptation responses to osmotic and temperature stress in Chromohalobacter salexigens, a bacterium with broad salinity tolerance. Saline systems 20080101
Growth arrest of BCR-ABL positive cells with a sequence-specific polyamide-chlorambucil conjugate. PloS one 20080101
Leucobacter chromiireducens subsp. solipictus subsp. nov., a pigmented bacterium isolated from the nematode Caenorhabditis elegans, and emended description of L. chromiireducens. International journal of systematic and evolutionary microbiology 20071201
Semi-synthesis of polymyxin B (2-10) and colistin (2-10) analogs employing the Trichloroethoxycarbonyl (Troc) group for side chain protection of alpha,gamma-diaminobutyric acid residues. Chemical & pharmaceutical bulletin 20071201
Alpha-diaminobutyric acid-linked hairpin polyamides. Bioorganic & medicinal chemistry 20071115
Antitumor effects of the MIG and IP-10 genes transferred with poly [D,L-2,4-diaminobutyric acid] on murine neuroblastoma. Cancer gene therapy 20070801
Chiroptical properties of diamino carboxylic acids. Chirality 20070701
Biochemical characterisation of recombinant Streptomyces pristinaespiralis L-lysine cyclodeaminase. Biochimie 20070501
Leifsonia ginsengi sp. nov., isolated from ginseng root. International journal of systematic and evolutionary microbiology 20070201
Metabolic manipulation of glioblastoma in vivo by retrograde microdialysis of L-2, 4 diaminobutyric acid (DAB). Journal of neuro-oncology 20061201
Synthesis, characterization and hybridization studies of new nucleo-gamma-peptides based on diaminobutyric acid. Journal of peptide science : an official publication of the European Peptide Society 20061201
[Identification of moderately halophilic strain DTY1 and study of its halotolerant mechanism]. Wei sheng wu xue bao = Acta microbiologica Sinica 20061201
Three generations of alpha,gamma-diaminobutyric acid modified poly(propyleneimine) dendrimers and their cisplatin-type platinum complexes. Journal of biochemical and biophysical methods 20061130
Plantibacter auratus sp. nov., in the family Microbacteriaceae. International journal of systematic and evolutionary microbiology 20061001
Characterization of the ectoine biosynthesis genes of haloalkalotolerant obligate methanotroph 'Methylomicrobium alcaliphilum 20Z'. Archives of microbiology 20060101
Electron capture dissociation mass spectrometry of peptide cations containing a lysine homologue: a mobile proton model for explaining the observation of b-type product ions. Rapid communications in mass spectrometry : RCM 20060101
Cloning, purification, and characterization of diaminobutyrate acetyltransferase from the halotolerant methanotroph Methylomicrobium alcaliphilum 20Z. Biochemistry. Biokhimiia 20050801
Phosphorylation-driven protein-protein interactions: a protein kinase sensing system. Journal of the American Chemical Society 20050601
Nature's protection racket. Chemistry & biology 20050601
Biosynthesis of the unique amino acid side chain of butirosin: possible protective-group chemistry in an acyl carrier protein-mediated pathway. Chemistry & biology 20050601
Organic compatible solutes of halotolerant and halophilic microorganisms. Saline systems 20050101
Liquid chromatography-mass spectrometry study towards the pH and temperature-induced N-acyl migration in polymyxin B. Journal of chromatography. A 20041126
GABAergic modulation of motor-driven behaviors in juvenile Drosophila and evidence for a nonbehavioral role for GABA transport. Journal of neurobiology 20041101
Coexpression, purification and characterization of the E and S subunits of coenzyme B(12) and B(6) dependent Clostridium sticklandii D-ornithine aminomutase in Escherichia coli. European journal of biochemistry 20041101
A new class of foldamers based on cis-gamma-amino-L-proline. Journal of the American Chemical Society 20040519
Effective transfer of interleukin-12 gene to solid tumors using a novel gene delivery system, poly [D,L-2,4-diaminobutyric acid]. Cancer gene therapy 20040201
Reclassification of Subtercola pratensis Behrendt et al. 2002 as Agreia pratensis comb. nov. International journal of systematic and evolutionary microbiology 20031101
Platinum complexes of diaminocarboxylic acids and their ethyl ester derivatives: the effect of the chelate ring size on antitumor activity and interactions with GMP and DNA. Journal of inorganic biochemistry 20030901
Leifsonia rubra sp. nov. and Leifsonia aurea sp. nov., psychrophiles from a pond in Antarctica. International journal of systematic and evolutionary microbiology 20030701
Agromyces aurantiacus sp. nov., isolated from a Chinese primeval forest. International journal of systematic and evolutionary microbiology 20030101
Unique antitumour effects of L-2,4 diaminobutyric acid on cultured hepatoma cells. Anticancer research 20030101
Does extracellular calcium determine what pool of GABA is the target for alpha-latrotoxin? Neurochemistry international 20020401
Pharmacological evidence for GABAergic regulation of specific behaviors in Drosophila melanogaster. Journal of neurobiology 20020215
Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor. Journal of molecular biology 20020111
Bi-directional transport of GABA in human embryonic kidney (HEK-293) cells stably expressing the rat GABA transporter GAT-1. British journal of pharmacology 20020101
[Effect of synaptosomal cytosolic [3H]GABA pool depletion on secretory ability of alpha-latrotoxin]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20020101
Novel spermine-amino acid conjugates and basic tripeptides enhance cleavage of the hairpin ribozyme at low magnesium ion concentration. Bioorganic & medicinal chemistry letters 20011203
Potent and selective peptide agonists of alpha-melanotropin action at human melanocortin receptor 4: their synthesis and biological evaluation in vitro. Biochemical and biophysical research communications 20010824
Abnormal elution behavior of ornitine derivatized with 1-fluoro-2,4-dinitrophenyl-5-leucinamide in advanced Marfey's method. Journal of chromatography. A 20010706
Synthesis and evaluation of dipeptide amides containing N omega-nitroarginine and D-2,4-diaminobutyric acids as inhibitors of neuronal nitric oxide synthase. Journal of enzyme inhibition 20010101
Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice. General pharmacology 19990301
GABAergic and dopaminergic systems may be involved in seizures induced by pyrimethamine in mice. General pharmacology 19941001
Cimetidine-induced seizures in mice. Antagonism by some GABAergic agents. Biochemical pharmacology 19931214
Effects of some GABAergic agents on quinine-induced seizures in mice. Experientia 19920715
Involvement of GABAergic mechanisms in chloroquine-induced seizures in mice. General pharmacology 19920301
Anticonvulsant activity of muscimol and gamma-aminobutyric acid against pyridoxal phosphate-induced epileptic seizures. Journal of neurochemistry 19810101

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