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Home > Pyridines > 304675-78-3
304675-78-3 | 2-Pyridinethiol, 1-oxide, sodium salt, hydrate (1:1:1)
CAS No: 304675-78-3 Catalog No: AG003083 MDL No:
Product Description
Catalog Number:
AG003083
Chemical Name:
2-Pyridinethiol, 1-oxide, sodium salt, hydrate (1:1:1)
CAS Number:
304675-78-3
Molecular Formula:
C5H7NNaO2S
Molecular Weight:
168.1693
IUPAC Name:
1-hydroxypyridine-2-thione
InChI:
InChI=1S/C5H5NOS/c7-6-4-2-1-3-5(6)8/h1-4,7H
InChI Key:
YBBJKCMMCRQZMA-UHFFFAOYSA-N
SMILES:
Sc1cccc[n+]1[O-].O.[Na]
UNII:
6GK82EC25D
NSC Number:
179790
Properties
Complexity:
162
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
127.009g/mol
Formal Charge:
0
Heavy Atom Count:
8
Hydrogen Bond Acceptor Count:
2
Hydrogen Bond Donor Count:
1
Isotope Atom Count:
0
Molecular Weight:
127.161g/mol
Monoisotopic Mass:
127.009g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
55.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.5
Literature
| Title | Journal |
|---|---|
| Bis(L-cysteinato)zincate(lI) as a coordination compound that induces metallothionein gene transcription without inducing cell-stress-related gene transcription. | Journal of inorganic biochemistry 20121201 |
| Evidence for an extracellular zinc-veneer in rodent brains from experiments with Zn-ionophores and ZnT3 knockouts. | ACS chemical neuroscience 20121017 |
| Species sensitivity distribution approach to primary risk analysis of the metal pyrithione photodegradation product, 2,2'-dipyridyldisulfide in the Inland Sea and induction of notochord undulation in fish embryos. | Aquatic toxicology (Amsterdam, Netherlands) 20120815 |
| Hydroxyl radical reaction with trans-resveratrol: initial carbon radical adduct formation followed by rearrangement to phenoxyl radical. | The journal of physical chemistry. B 20120621 |
| Nanomolar concentrations of zinc pyrithione increase cell susceptibility to oxidative stress induced by hydrogen peroxide in rat thymocytes. | Chemosphere 20120601 |
| Zinc induces caspase-dependent mitochondrial pathway of the programmed cell death in haemocytes of Drosophila melanogaster. | Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20120601 |
| The zinc transporter Zip14 influences c-Met phosphorylation and hepatocyte proliferation during liver regeneration in mice. | Gastroenterology 20120601 |
| Effects of metal pyrithione antifoulants on freshwater macrophyte Lemna gibba G3 determined by image analysis. | Ecotoxicology (London, England) 20120501 |
| New chemotypes acting as isozyme-selective carbonic anhydrase inhibitors with low affinity for the offtarget cytosolic isoform II. | Bioorganic & medicinal chemistry letters 20120315 |
| Protein kinase CK2 triggers cytosolic zinc signaling pathways by phosphorylation of zinc channel ZIP7. | Science signaling 20120207 |
| Iron-induced remodeling in cultured rat pulmonary artery endothelial cells. | Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20120201 |
| Zinc differentially regulates mitogen-activated protein kinases in human T cells. | The Journal of nutritional biochemistry 20120101 |
| Characterization of the fungal microbiota (mycobiome) in healthy and dandruff-afflicted human scalps. | PloS one 20120101 |
| Risks of using antifouling biocides in aquaculture. | International journal of molecular sciences 20120101 |
| Microwave spectra and gas phase structural parameters for N-hydroxypyridine-2(1H)-thione. | The journal of physical chemistry. A 20111222 |
| The versatile binding mode of transition-state analogue inhibitors of tyrosinase towards dicopper(II) model complexes: experimental and theoretical investigations. | Chemistry (Weinheim an der Bergstrasse, Germany) 20111125 |
| The antifungal mechanism of action of zinc pyrithione. | The British journal of dermatology 20111001 |
| Single-substance and mixture toxicity of five pharmaceuticals and personal care products to marine periphyton communities. | Environmental toxicology and chemistry 20110901 |
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| Glucose regulates free cytosolic Zn²⁺ concentration, Slc39 (ZiP), and metallothionein gene expression in primary pancreatic islet β-cells. | The Journal of biological chemistry 20110722 |
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| LPS-induced decrease in intracellular labile zinc, [Zn]i, contributes to apoptosis in cultured sheep pulmonary artery endothelial cells. | American journal of physiology. Lung cellular and molecular physiology 20110401 |
| Direct observation of the β-carotene reaction with hydroxyl radical. | The journal of physical chemistry. B 20110310 |
| Identifying chelators for metalloprotein inhibitors using a fragment-based approach. | Journal of medicinal chemistry 20110127 |
| Rate constants for cyclizations of α-hydroxy radical clocks. | Organic & biomolecular chemistry 20110121 |
| Toxicity and metabolism of copper pyrithione and its degradation product, 2,2'-dipyridyldisulfide in a marine polychaete. | Chemosphere 20110101 |
| The zinc transporter SLC39A14/ZIP14 controls G-protein coupled receptor-mediated signaling required for systemic growth. | PloS one 20110101 |
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| Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture. | PLoS pathogens 20101101 |
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| DNA microarray analysis suggests that zinc pyrithione causes iron starvation to the yeast Saccharomyces cerevisiae. | Journal of bioscience and bioengineering 20100501 |
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| A bacterial biosensor for oxidative stress using the constitutively expressed redox-sensitive protein roGFP2. | Sensors (Basel, Switzerland) 20100101 |
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| Metal ionophores - an emerging class of anticancer drugs. | IUBMB life 20091101 |
| Synthesis and characterization of a pyridine-2-thiol N-oxide gold(I) complex with potent antiproliferative effect against Trypanosoma cruzi and Leishmania sp. insight into its mechanism of action. | Journal of inorganic biochemistry 20091001 |
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| 2,4,6-Tris(1-oxo-2-pyridylsulfanylmeth-yl)mesitylene methanol solvate. | Acta crystallographica. Section E, Structure reports online 20080601 |
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