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303-98-0

303-98-0 | coenzyme Q10

CAS No: 303-98-0 Catalog No: AG00396N MDL No:MFCD00042919

Product Description

Catalog Number:
AG00396N
Chemical Name:
coenzyme Q10
CAS Number:
303-98-0
Molecular Formula:
C59H90O4
Molecular Weight:
863.3435
MDL Number:
MFCD00042919
IUPAC Name:
2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl]-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
InChI:
InChI=1S/C59H90O4/c1-44(2)24-15-25-45(3)26-16-27-46(4)28-17-29-47(5)30-18-31-48(6)32-19-33-49(7)34-20-35-50(8)36-21-37-51(9)38-22-39-52(10)40-23-41-53(11)42-43-55-54(12)56(60)58(62-13)59(63-14)57(55)61/h24,26,28,30,32,34,36,38,40,42H,15-23,25,27,29,31,33,35,37,39,41,43H2,1-14H3/b45-26+,46-28+,47-30+,48-32+,49-34+,50-36+,51-38+,52-40+,53-42+
InChI Key:
ACTIUHUUMQJHFO-UPTCCGCDSA-N
SMILES:
COC1=C(OC)C(=O)C(=C(C1=O)C/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CCC=C(C)C)\C)\C)\C)\C)\C)\C)\C)\C)\C)C
EC Number:
206-147-9
UNII:
EJ27X76M46
NSC Number:
140865

Properties

Complexity:
1840  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
9  
Exact Mass:
862.684g/mol
Formal Charge:
0
Heavy Atom Count:
63  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
863.365g/mol
Monoisotopic Mass:
862.684g/mol
Rotatable Bond Count:
31  
Topological Polar Surface Area:
52.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
19.4  

Literature

Title Journal
Protective effects of coenzyme Q10 nanoparticles on dichlorvos-induced hepatotoxicity and mitochondrial/lysosomal injury. Environmental toxicology 20180201
The potential benefit of combined versus monotherapy of coenzyme Q10 and fluoxetine on depressive-like behaviors and intermediates coupled to Gsk-3β in rats. Toxicology and applied pharmacology 20180201
Protective effect of Co-enzyme Q10 On doxorubicin-induced cardiomyopathy of rat hearts. Environmental toxicology 20170201
Sodium arsenite-induced myocardial bruise in rats: Ameliorative effect of naringin via TGF-β/Smad and Nrf/HO pathways. Chemico-biological interactions 20160625
Elucidation of the mechanism of atorvastatin-induced myopathy in a rat model. Toxicology 20160601
Effect of pre- and post-combined multidoses of epigallocatechin gallate and coenzyme Q10 on cisplatin-induced oxidative stress in rat kidney. Journal of biochemical and molecular toxicology 20150201
Reduction of coenzyme q10 content: a possible effect of isoproterenol on heart failure and myocardial infarction in rat. Drug research 20140401
Resveratrol stimulates mitochondrial bioenergetics to protect retinal pigment epithelial cells from oxidative damage. Investigative ophthalmology & visual science 20130927
Nucleoside reverse transcriptase inhibitors induce a mitophagy-associated endothelial cytotoxicity that is reversed by coenzyme Q10 cotreatment. Toxicological sciences : an official journal of the Society of Toxicology 20130801
Coenzyme Q10 protects Pc12 cells from cisplatin-induced DNA damage and neurotoxicity. Neurotoxicology 20130501
Nutritional pork meat compounds as affected by ham dry-curing. Meat science 20130101
Alcohol depletes coenzyme-Q(10) associated with increased TNF-alpha secretion to induce cytotoxicity in HepG2 cells. Toxicology 20121208
Coenzyme Q10 increases the fatty acid oxidation through AMPK-mediated PPARα induction in 3T3-L1 preadipocytes. Cellular signalling 20121201
Simple and fast HPLC method for simultaneous determination of retinol, tocopherols, coenzyme Q(10) and carotenoids in complex samples. Food chemistry 20121015
Coenzyme Q(10) supplementation ameliorates inflammatory signaling and oxidative stress associated with strenuous exercise. European journal of nutrition 20121001
CoEnzyme Q10 and riboflavin: the mitochondrial connection. Headache 20121001
Coenzyme Q10 protects retinal cells from apoptosis induced by radiation in vitro and in vivo. Journal of radiation research 20120901
Nutraceuticals for blood pressure control in patients with high-normal or grade 1 hypertension. High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension 20120901
Novel solid self-emulsifying drug delivery system of coenzyme Q₁₀ with improved photochemical and pharmacokinetic behaviors. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120815
Mixture-process variable approach to optimize a microemulsion electrokinetic chromatography method for the quality control of a nutraceutical based on coenzyme Q10. Talanta 20120815
Coenzyme Q10 reverses mitochondrial dysfunction in atorvastatin-treated mice and increases exercise endurance. Journal of applied physiology (Bethesda, Md. : 1985) 20120801
Magnesium ascorbyl phosphate and coenzyme Q10 protect keratinocytes against UVA irradiation by suppressing glutathione depletion. Molecular medicine reports 20120801
Coenzyme Q10 deficiency in patients with Parkinson's disease. Journal of the neurological sciences 20120715
[Effects of atorvastatin and CoQ(10) on myocardial energy metabolism in rabbits with hypercholesterolemia]. Zhonghua yi xue za zhi 20120710
Pharmacokinetic comparison of a generic coenzyme Q₁₀ solubilizate and a formulation with soybean phytosterols. Phytotherapy research : PTR 20120701
Update on clinical aspects and treatment of selected vitamin-responsive disorders II (riboflavin and CoQ 10). Journal of inherited metabolic disease 20120701
Effects of coenzyme Q10 supplementation on inflammatory markers (high-sensitivity C-reactive protein, interleukin-6, and homocysteine) in patients with coronary artery disease. Nutrition (Burbank, Los Angeles County, Calif.) 20120701
Antioxidants for Alzheimer disease: a randomized clinical trial with cerebrospinal fluid biomarker measures. Archives of neurology 20120701
Does consumption of two portions of salmon per week enhance the antioxidant defense system in pregnant women? Antioxidants & redox signaling 20120615
Mitochondrial dysfunction in antiphospholipid syndrome: implications in the pathogenesis of the disease and effects of coenzyme Q(10) treatment. Blood 20120614
Reversal of slow growth and heartbeat through the restoration of mitochondrial function in clk-1-deficient mouse embryos by exogenous administration of coenzyme Q10. Experimental gerontology 20120601
The use of muscle biopsy in the diagnosis of undefined ataxia with cerebellar atrophy in children. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20120501
Coenzyme Q(10), vitamin E, selenium, and methionine in the treatment of chronic recurrent viral mucocutaneous infections. Nutrition (Burbank, Los Angeles County, Calif.) 20120501
Protective efficacy of coenzyme Q10 against DDVP-induced cognitive impairments and neurodegeneration in rats. Neurotoxicity research 20120501
CoQ(10) deficiencies and MNGIE: two treatable mitochondrial disorders. Biochimica et biophysica acta 20120501
Coenzyme Q10 prevents GDP-sensitive mitochondrial uncoupling, glomerular hyperfiltration and proteinuria in kidneys from db/db mice as a model of type 2 diabetes. Diabetologia 20120501
Coenzyme Q10 attenuates diastolic dysfunction, cardiomyocyte hypertrophy and cardiac fibrosis in the db/db mouse model of type 2 diabetes. Diabetologia 20120501
Cellular and molecular mechanisms of antioxidants in Parkinson's disease. Nutritional neuroscience 20120501
Treatment for mitochondrial disorders. The Cochrane database of systematic reviews 20120418
Marivita hallyeonensis sp. nov., isolated from seawater, reclassification of Gaetbulicola byunsanensis as Marivita byunsanensis comb. nov. and emended description of the genus Marivita Hwang et al. 2009. International journal of systematic and evolutionary microbiology 20120401
Coenzyme Q10 supplementation and exercise-induced oxidative stress in humans. Nutrition (Burbank, Los Angeles County, Calif.) 20120401
Coenzyme Q10 content in follicular fluid and its relationship with oocyte fertilization and embryo grading. Archives of gynecology and obstetrics 20120401
Safety and efficacy of antioxidants-loaded nanoparticles for an anti-aging application. Journal of biomedical nanotechnology 20120401
Beneficial modulation from a high-purity caviar-derived homogenate on chronological skin aging. Rejuvenation research 20120401
The effect of coenzyme Q10 and curcumin on chronic methanol intoxication induced retinopathy in rats. Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20120401
Coenzyme Q10 supplementation reduces oxidative stress and increases antioxidant enzyme activity in patients with coronary artery disease. Nutrition (Burbank, Los Angeles County, Calif.) 20120301
Oral treatment with amitriptyline induces coenzyme Q deficiency and oxidative stress in psychiatric patients. Journal of psychiatric research 20120301
Hepatoprotective effect of coenzyme Q10 in rats with acetaminophen toxicity. Environmental toxicology and pharmacology 20120301
Coenzyme Q10, hyperhomocysteinemia and MTHFR C677T polymorphism in levodopa-treated Parkinson's disease patients. Neuromolecular medicine 20120301
Effects of treatment with coenzyme Q10 on exercised rat aorta. Acta physiologica Hungarica 20120301
Coenzyme Q10 effects on creatine kinase activity and mood in geriatric bipolar depression. Journal of geriatric psychiatry and neurology 20120301
Coenzyme Q(10) production by immobilized Sphingomonas sp. ZUTE03 via a conversion-extraction coupled process in a three-phase fluidized bed reactor. Enzyme and microbial technology 20120210
Antioxidants, like coenzyme Q10, selenite, and curcumin, inhibited osteoclast differentiation by suppressing reactive oxygen species generation. Biochemical and biophysical research communications 20120210
Mechanisms of mitochondrial diseases. Annals of medicine 20120201
Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes. Free radical biology & medicine 20120201
Association of colony morphology with coenzyme Q(10) production and its enhancement from Rhizobium radiobacter T6102W by addition of isopentenyl alcohol as a precursor. Journal of microbiology and biotechnology 20120201
Preparation of coenzyme Q10 liposomes using supercritical anti-solvent technique. Journal of microencapsulation 20120101
Towards a modern definition of vitamin E-evidence for a quinone hypothesis. Bioorganic & medicinal chemistry letters 20120101
Coenzyme Q10 protects against amyloid beta-induced neuronal cell death by inhibiting oxidative stress and activating the P13K pathway. Neurotoxicology 20120101
The use of complementary and alternative medicine among people living with diabetes in Sydney. BMC complementary and alternative medicine 20120101
Effects of inhibiting CoQ10 biosynthesis with 4-nitrobenzoate in human fibroblasts. PloS one 20120101
Ratio of lipid parameters to coenzyme Q10 could be used as biomarker of the development of early complications of obesity in children. Bratislavske lekarske listy 20120101
Coenzyme Q metabolism is disturbed in high fat diet-induced non-alcoholic fatty liver disease in rats. International journal of molecular sciences 20120101
A water soluble CoQ10 formulation improves intracellular distribution and promotes mitochondrial respiration in cultured cells. PloS one 20120101
Coenzyme Q10 levels in β-thalassemia and its association with ferritin levels and chelation therapy. Hemoglobin 20120101
Oxidative stress correlates with headache symptoms in fibromyalgia: coenzyme Q₁₀ effect on clinical improvement. PloS one 20120101
Cyclic Vomiting Syndrome (CVS): is there a difference based on onset of symptoms--pediatric versus adult? BMC gastroenterology 20120101
The relationship between coenzyme Q10, oxidative stress, and antioxidant enzymes activities and coronary artery disease. TheScientificWorldJournal 20120101
A combination of lipoic acid plus coenzyme Q10 induces PGC1α, a master switch of energy metabolism, improves stress response, and increases cellular glutathione levels in cultured C2C12 skeletal muscle cells. Oxidative medicine and cellular longevity 20120101
Statin treatment increases lifespan and improves cardiac health in Drosophila by decreasing specific protein prenylation. PloS one 20120101
Effects of CoQ10 supplementation and swimming training on exhaustive exercise-induced oxidative stress in rat heart. Bratislavske lekarske listy 20120101
Effect of combination therapy with coenzyme Q10 on functional and metabolic parameters in patients with type 1 diabetes mellitus. Bulletin of experimental biology and medicine 20120101
Mitochondria-derived superoxide links to tourniquet-induced apoptosis in mouse skeletal muscle. PloS one 20120101
Impact of oral ubiquinol on blood oxidative stress and exercise performance. Oxidative medicine and cellular longevity 20120101
Antioxidant vitamins C, E and coenzyme Q10 vs dexamethasone: comparisons of their effects in pulmonary contusion model. Journal of cardiothoracic surgery 20120101
Correlations between oxidative DNA damage, oxidative stress and coenzyme Q10 in patients with coronary artery disease. International journal of medical sciences 20120101
Recombinant expression of His-tagged saposin B and pH-dependent binding to the lipid coenzyme Q10. Analytical biochemistry 20111215
Mitochondrial and metabolic-based protective strategies in Huntington's disease: the case of creatine and coenzyme Q. Reviews in the neurosciences 20111202
Postprandial antioxidant effect of the Mediterranean diet supplemented with coenzyme Q10 in elderly men and women. Age (Dordrecht, Netherlands) 20111201
Coenzyme Q10 enhances the anticonvulsant effect of phenytoin in pilocarpine-induced seizures in rats and ameliorates phenytoin-induced cognitive impairment and oxidative stress. Epilepsy & behavior : E&B 20111201
Long-term effects of nutraceuticals (berberine, red yeast rice, policosanol) in elderly hypercholesterolemic patients. Advances in therapy 20111201
Determination of coenzyme Q10, coenzyme Q9, and melatonin contents in virgin argan oils: comparison with other edible vegetable oils. Journal of agricultural and food chemistry 20111123
Plasma coenzyme Q10 is increased during gestational diabetes. Diabetes research and clinical practice 20111101
Identification of bottlenecks in Escherichia coli engineered for the production of CoQ(10). Metabolic engineering 20111101
In vitro-in vivo study of CoQ10-loaded lipid nanoparticles in comparison with nanocrystals. International journal of pharmaceutics 20111031
Reaction of superoxide radical with quinone molecules. The journal of physical chemistry. A 20111027
Coenzyme Q10 protects neurons against neurotoxicity in hippocampal slice culture. Neuroreport 20111005
Oral bioavailability, therapeutic efficacy and reactive oxygen species scavenging properties of coenzyme Q10-loaded polymeric nanoparticles. Biomaterials 20111001
Anodic oxidation of oxidized forms of coenzymes Q(10) and Q(0) on carbon electrodes in acetic acid solutions. Bioelectrochemistry (Amsterdam, Netherlands) 20111001
Protection of dichlorvos induced oxidative stress and nigrostriatal neuronal death by chronic coenzyme Q10 pretreatment. Toxicology and applied pharmacology 20111001
Validated HPLC method for the quantitative determination of CoQ(10) in dog plasma and its application to a pharmacokinetic study. Biomedical chromatography : BMC 20110901
The effects of ozone therapy and coenzyme Q₁₀ combination on oxidative stress markers in healthy subjects. Irish journal of medical science 20110901
Coenzyme Q10 improves seminal oxidative defense but does not affect on semen parameters in idiopathic oligoasthenoteratozoospermia: a randomized double-blind, placebo controlled trial. Journal of endocrinological investigation 20110901
The effect of antioxidants on the response of the rabbit urinary bladder to in vitro ischemia/reperfusion. Molecular and cellular biochemistry 20110901
Combined atorvastatin and coenzyme Q10 improve the left ventricular function in isoproterenol-induced heart failure in rat. European journal of pharmacology 20110901
Changes in broiler chick tissue concentrations of lipid-soluble antioxidants immediately post-hatch. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20110901
Why are there no proven therapies for genetic mitochondrial diseases? Mitochondrion 20110901
Release of lipophilic molecules during in vitro digestion of soy protein-stabilized emulsions. Molecular nutrition & food research 20110901
Relationship between plasma coenzyme Q10, asymmetric dimethylarginine and arterial stiffness in patients with phenotypic or genotypic familial hypercholesterolemia on long-term statin therapy. Atherosclerosis 20110901
Coenzyme Q10 suppresses oxLDL-induced endothelial oxidative injuries by the modulation of LOX-1-mediated ROS generation via the AMPK/PKC/NADPH oxidase signaling pathway. Molecular nutrition & food research 20110901
Spontaneous ultraweak photon emission imaging of oxidative metabolic processes in human skin: effect of molecular oxygen and antioxidant defense system. Journal of biomedical optics 20110901
Coenzyme Q10 and cognition in atorvastatin treated dogs. Neuroscience letters 20110826
Solanesol: added value from Solanaceous waste. Phytochemistry 20110801
CINRG pilot trial of coenzyme Q10 in steroid-treated Duchenne muscular dystrophy. Muscle & nerve 20110801
Rosuvastatin combined with regular exercise preserves coenzyme Q10 levels associated with a significant increase in high-density lipoprotein cholesterol in patients with coronary artery disease. Atherosclerosis 20110701
[Tamoxifen combined with coenzyme Q10 for idiopathic oligoasthenospermia]. Zhonghua nan ke xue = National journal of andrology 20110701
α-Tocotrienol quinone modulates oxidative stress response and the biochemistry of aging. Bioorganic & medicinal chemistry letters 20110615
Reversal of mitochondrial dysfunction by coenzyme Q10 supplement improves endothelial function in patients with ischaemic left ventricular systolic dysfunction: a randomized controlled trial. Atherosclerosis 20110601
Low plasma coenzyme Q(10) levels and breast cancer risk in Chinese women. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20110601
Up-regulation of antioxidant enzymes and coenzyme Q(10) in a human oral cancer cell line with acquired bleomycin resistance. Free radical research 20110601
Reinvestigation of coenzyme Q10 isolation from Sporidiobolus johnsonii. Chemistry & biodiversity 20110601
Oxidative stress and antioxidant defense in plasma after repeated bouts of supramaximal exercise: the effect of coenzyme Q10. The Journal of sports medicine and physical fitness 20110601
Effects of exogenous antioxidants on oxidative stress in pregnancy. Journal of medicine and life 20110515
Fatal heart failure associated with CoQ10 and multiple OXPHOS deficiency in a child with propionic acidemia. Mitochondrion 20110501
Age-related changes in brain mitochondrial DNA deletion and oxidative stress are differentially modulated by dietary fat type and coenzyme Q₁₀. Free radical biology & medicine 20110501
Coenzyme Q10 production by Sphingomonas sp. ZUTE03 with novel precursors isolated from tobacco waste in a two-phase conversion system. Journal of microbiology and biotechnology 20110501
[Effects of milk and coenzyme Q10 on the interference of acrylonitrile on vascular endothelial functions]. Zhonghua yi xue za zhi 20110426
Low coenzyme Q₁₀ levels and the outcome of statin treatment in heart failure. Journal of the American College of Cardiology 20110405
Neuropharmacological effects of lipoic acid and ubiquinone on δ-aminolevulinic dehydratase, Na(+) , K(+) -ATPase, and Mg(2+) -ATPase activities in rat hippocampus after pilocarpine-induced seizures. Fundamental & clinical pharmacology 20110401
The reduced form of coenzyme Q10 decreases the expression of lipopolysaccharide-sensitive genes in human THP-1 cells. Journal of medicinal food 20110401
Effects of coenzyme Q10 on arterial stiffness, metabolic parameters, and fatigue in obese subjects: a double-blind randomized controlled study. Journal of medicinal food 20110401
Coenzyme q10 and creatine in heart failure: micronutrients, macrobenefit? Clinical cardiology 20110401
Coenzyme Q10 terclatrate and creatine in chronic heart failure: a randomized, placebo-controlled, double-blind study. Clinical cardiology 20110401
Exploring by pulsed EPR the electronic structure of ubisemiquinone bound at the QH site of cytochrome bo3 from Escherichia coli with in vivo 13C-labeled methyl and methoxy substituents. The Journal of biological chemistry 20110325
Coenzyme Q10 counteracts testicular injury induced by sodium arsenite in rats. European journal of pharmacology 20110325
Differential effects of coenzyme Q10 and α-lipoic acid on two models of in vitro oxidative damage to the rabbit urinary bladder. International urology and nephrology 20110301
Rosuvastatin lowers coenzyme Q10 levels, but not mitochondrial adenosine triphosphate synthesis, in children with familial hypercholesterolemia. The Journal of pediatrics 20110301
Genetics of the coenzyme Q10 pathway and rosuvastatin-induced muscle effects. The Journal of pediatrics 20110301
Antioxidants in the treatment of diabetes. Current diabetes reviews 20110301
Carnitine and coenzyme Q10 levels in individuals with Prader-Willi syndrome. American journal of medical genetics. Part A 20110301
Effects of carnitine and coenzyme Q10 on lipid profile and serum levels of lipoprotein(a) in maintenance hemodialysis patients on statin therapy. Iranian journal of kidney diseases 20110301
Maternal plasma and amniotic fluid coenzyme Q10 levels in preterm and term gestations: a pilot study. Archives of gynecology and obstetrics 20110301
In situ surface-enhanced Raman scattering and X-ray photoelectron spectroscopic investigation of coenzyme Q10 on silver electrode. Physical chemistry chemical physics : PCCP 20110214
Novosphingobium soli sp. nov., isolated from soil. International journal of systematic and evolutionary microbiology 20110201
Paraoxonase 2 deficiency alters mitochondrial function and exacerbates the development of atherosclerosis. Antioxidants & redox signaling 20110201
Ginkgolide B complex efficacy for brief prophylaxis of migraine in school-aged children: an open-label study. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20110201
Renal preservation effect of ubiquinol, the reduced form of coenzyme Q10. Clinical and experimental nephrology 20110201
Tourniquet-induced acute ischemia-reperfusion injury in mouse skeletal muscles: Involvement of superoxide. European journal of pharmacology 20110110
Oxidative imbalance in different neurodegenerative diseases with memory impairment. Neuro-degenerative diseases 20110101
Coenzyme Q(10) production directly from precursors by free and gel-entrapped Sphingomonas sp. ZUTE03 in a water-organic solvent, two-phase conversion system. Applied microbiology and biotechnology 20110101
Effect of an antioxidant-rich multivitamin supplement in cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society 20110101
Differential effects of statins on endogenous H2S formation in perivascular adipose tissue. Pharmacological research 20110101
Effect of mitochondrial dysfunction and oxidative stress on endogenous levels of coenzyme Q(10) in human cells. Journal of biochemical and molecular toxicology 20110101
Drug-induced leukoencephalopathy presenting as catatonia. General hospital psychiatry 20110101
Coenzyme Q10 reduces ethanol-induced apoptosis in corneal fibroblasts. PloS one 20110101
Novel formulation and evaluation of a Q10-loaded solid lipid nanoparticle cream: in vitro and in vivo studies. International journal of nanomedicine 20110101
Coenzyme Q10 and its relation with oxidant and antioxidant system markers in patients with end-stage renal disease. Renal failure 20110101
Nutritional assessment in heart failure patients. Congestive heart failure (Greenwich, Conn.) 20110101
Coenzyme Q10 decreases amyloid pathology and improves behavior in a transgenic mouse model of Alzheimer's disease. Journal of Alzheimer's disease : JAD 20110101
Effect of coenzyme Q10 on ischemia and neuronal damage in an experimental traumatic brain-injury model in rats. BMC neuroscience 20110101
Targeting mitochondrial dysfunction and neurodegeneration by means of coenzyme Q10 and its analogues. Current medicinal chemistry 20110101
Coenzyme Q10 levels are low and may be associated with the inflammatory cascade in septic shock. Critical care (London, England) 20110101
High degree of efficacy in the treatment of cyclic vomiting syndrome with combined co-enzyme Q10, L-carnitine and amitriptyline, a case series. BMC neurology 20110101
[Application of coenzyme Q(10) in combination therapy of arterial hypertension]. Kardiologiia 20110101
[Myocardial cytoprotectors, a reserve therapeutic modality for patients with stable angina of effort]. Klinicheskaia meditsina 20110101
Statin intolerance: now a solved problem. Journal of postgraduate medicine 20110101
Lipid peroxidation, DNA damage and coenzyme Q10 in lung cancer patients--markers for risk assessment? Asian Pacific journal of cancer prevention : APJCP 20110101
Coenzyme q10 ameliorates ultraviolet B irradiation induced cell death through inhibition of mitochondrial intrinsic cell death pathway. International journal of molecular sciences 20110101
Hormonal influence on coenzyme Q(10) levels in blood plasma. International journal of molecular sciences 20110101
[Cardiotoxicity of conservative treatment of solid tumors]. Likars'ka sprava 20110101
Efficient Lewis acid ionic liquid-catalyzed synthesis of the key intermediate of coenzyme Q10 under microwave irradiation. Molecules (Basel, Switzerland) 20101222
Coenzyme Q10: a novel gastroprotective effect via modulation of vascular permeability, prostaglandin E₂, nitric oxide and redox status in indomethacin-induced gastric ulcer model. European journal of pharmacology 20101215
Possible role of vitamin E, coenzyme Q10 and rutin in protection against cerebral ischemia/reperfusion injury in irradiated rats. International journal of radiation biology 20101201
Spin labeling of the Escherichia coli NADH ubiquinone oxidoreductase (complex I). Biochimica et biophysica acta 20101201
Coenzyme Q10 in combination with steroid therapy for treatment of sudden sensorineural hearing loss: a controlled prospective study. Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery 20101201
A randomized, double-blind, crossover study on the pharmacokinetics of a novel formulation of CoQ₁₀ with pyridoxal 5'-phosphate and phosphatidyl choline. Journal of dietary supplements 20101201
Coenzyme Q(10) and statin myalgia: what is the evidence? Current atherosclerosis reports 20101101
Bioavailability enhancement of coenzyme Q10: an extensive review of patents. Recent patents on drug delivery & formulation 20101101
Saccharomyces cerevisiae coq10 null mutants are responsive to antimycin A. The FEBS journal 20101101
A randomized trial of coenzyme Q10 in mitochondrial disorders. Muscle & nerve 20101101
Antioxidant effects of melatonin and coenzyme Q10 on oxidative damage caused by single-dose ochratoxin A in rat kidney. The Chinese journal of physiology 20101031
Coenzyme Q10, rosuvastatin, and clinical outcomes in heart failure: a pre-specified substudy of CORONA (controlled rosuvastatin multinational study in heart failure). Journal of the American College of Cardiology 20101005
Coenzyme Q10 and statins in heart failure: the dog that didn't bark. Journal of the American College of Cardiology 20101005
Synthesis of coenzyme Q10 and beta-carotene by yeasts isolated from antarctic soil and lichen in response to ultraviolet and visible radiations. Applied biochemistry and biotechnology 20101001
Quality characteristics and composition of the longissimus muscle in the short-loin from male and female farmed red deer in New Zealand. Meat science 20101001
Perioperative metabolic therapy improves redox status and outcomes in cardiac surgery patients: a randomised trial. Heart, lung & circulation 20101001
Management of statin-intolerant high-risk patients. Current vascular pharmacology 20100901
Evidence-based management of statin myopathy. Current atherosclerosis reports 20100901
Hydrogen bonds between nitrogen donors and the semiquinone in the Q(B) site of bacterial reaction centers. Journal of the American Chemical Society 20100825
Preparation and characterization of liposomal coenzyme Q10 for in vivo topical application. International journal of pharmaceutics 20100816
Sedentary aging increases resting and exercise-induced intramuscular free radical formation. Journal of applied physiology (Bethesda, Md. : 1985) 20100801
Parkinson's disease: mitochondrial molecular pathology, inflammation, statins, and therapeutic neuroprotective nutrition. Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition 20100801
The lipophilic antioxidants alpha-tocopherol and coenzyme Q10 reduce the replicative lifespan of Saccharomyces cerevisiae. Free radical biology & medicine 20100715
Losartan improved respiratory function and coenzyme Q content in brain mitochondria of young spontaneously hypertensive rats. Cellular and molecular neurobiology 20100701
A galactose-free diet enriched in soy isoflavones and antioxidants results in delayed onset of symptoms of Krabbe disease in twitcher mice. Molecular genetics and metabolism 20100701
A-Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance--part 10. British journal of sports medicine 20100701
Nutritional treatments for acute myocardial infarction. Alternative medicine review : a journal of clinical therapeutic 20100701
The advantages of a novel CoQ10 delivery system in skin photo-protection. International journal of pharmaceutics 20100615
Supplementation with the reduced form of Coenzyme Q10 decelerates phenotypic characteristics of senescence and induces a peroxisome proliferator-activated receptor-alpha gene expression signature in SAMP1 mice. Molecular nutrition & food research 20100601
Dietary coenzyme Q10 does not protect against cigarette smoke-augmented atherosclerosis in apoE-deficient mice. Free radical biology & medicine 20100601
On call. I'm a 61-year-old man with high blood pressure. My doctor wants me to take Zocor to lower my cholesterol, but I'm worried about muscle damage. I found a Web site that claimed coenyzme Q(10) would help. Is that right? Harvard men's health watch 20100601
[Mouthwash solutions with microencapsuled natural extracts: Efficiency for dental plaque and gingivitis]. Revue de stomatologie et de chirurgie maxillo-faciale 20100601
HYSCORE evidence that endogenous mena- and ubisemiquinone bind at the same Q site (Q(D)) of Escherichia coli nitrate reductase A. Journal of the American Chemical Society 20100505
Coenzyme Q10 and oxidative stress markers in seminal plasma of Iraqi patients with male infertility. Saudi medical journal 20100501
Fiber phenotype and coenzyme Q₁₀ content in Turkey skeletal muscles. Cells, tissues, organs 20100501
Effect of beer consumption on levels of complex I and complex IV liver and heart mitochondrial enzymes and coenzymes Q9 and Q10 in adriamycin-treated rats. European journal of nutrition 20100401
Cadmium-induced lipid peroxidation and changes in antioxidant defense system in the rat testes: protective role of coenzyme Q(10) and vitamin E. Reproductive toxicology (Elmsford, N.Y.) 20100401
Ubisol-Aqua: coenzyme Q10 prevents antiretroviral toxic neuropathy in an in vitro model. Current HIV research 20100401
Lovastatin prevents carcinogenesis in a rat model for liver cancer. Effects of ubiquinone supplementation. Anticancer research 20100401
Ascochlorin is a novel, specific inhibitor of the mitochondrial cytochrome bc1 complex. Biochimica et biophysica acta 20100301
Nanosized self-emulsifying lipid vesicles of diacylglycerol-PEG lipid conjugates: biophysical characterization and inclusion of lipophilic dietary supplements. Biochimica et biophysica acta 20100301
Current drug targets for antihyperlipidemic therapy. Mini reviews in medicinal chemistry 20100301
Metabolic supplementation with enhanced external counterpulsation improves myocardial function in acquired cardiomyopathy: a case report. Journal of alternative and complementary medicine (New York, N.Y.) 20100301
Early pharmacologic treatment in Parkinson's disease. The American journal of managed care 20100301
Effects of ubiquinone on hydroperoxide concentration and antioxidant enzymatic activities in the rat hippocampus during pilocarpine-induced seizures. Brain research 20100222
Recovery of solanesol from tobacco as a value-added byproduct for alternative applications. Bioresource technology 20100201
Effects of acetylsalicylic acid on serum paraoxonase activity, Ox-LDL, coenzyme Q10 and other oxidative stress markers in healthy volunteers. Clinical biochemistry 20100201
Neuroprotection for optic nerve disorders. Current opinion in neurology 20100201
Current state of coenzyme Q(10) production and its applications. Applied microbiology and biotechnology 20100201
Post-polio syndrome: Pathophysiological hypotheses, diagnosis criteria, drug therapy. Annals of physical and rehabilitation medicine 20100201
Antifatigue effect of coenzyme Q10 in mice. Journal of medicinal food 20100201
Effects of coenzyme Q10 supplementation on plasma adiponectin, interleukin-6, and tumor necrosis factor-alpha levels in men. Journal of medicinal food 20100201
Atorvastatin increases blood ratios of vitamin E/low-density lipoprotein cholesterol and coenzyme Q10/low-density lipoprotein cholesterol in hypercholesterolemic patients. Nutrition research (New York, N.Y.) 20100201
Levels of reduced and oxidized coenzyme Q-10 and 8-hydroxy-2'-deoxyguanosine in the cerebrospinal fluid of patients with living Parkinson's disease demonstrate that mitochondrial oxidative damage and/or oxidative DNA damage contributes to the neurodegenerative process. Neuroscience letters 20100118
Mitochondrial DNA haplogroups influence the therapeutic response to riboflavin in migraineurs. Neurology 20100112
Enhanced production of coenzyme Q10 by overexpressing HMG-CoA reductase and induction with arachidonic acid in Schizosaccharomyces pombe. Applied biochemistry and biotechnology 20100101
Controlling reactive oxygen species in skin at their source to reduce skin aging. Rejuvenation research 20100101
Coenzyme Q10 in neuromuscular and neurodegenerative disorders. Current drug targets 20100101
Antioxidant therapy in human endocrine disorders. Medical science monitor : international medical journal of experimental and clinical research 20100101
Antioxidants and skin care: the essentials. Plastic and reconstructive surgery 20100101
Mitochondrial dysfunction and mitophagy activation in blood mononuclear cells of fibromyalgia patients: implications in the pathogenesis of the disease. Arthritis research & therapy 20100101
Treatment of cyclic vomiting syndrome with co-enzyme Q10 and amitriptyline, a retrospective study. BMC neurology 20100101
Existence of compensatory defense mechanisms against oxidative stress and hypertension in preeclampsia. Hypertension in pregnancy 20100101
Mitochondrial therapies for Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society 20100101
Comprehensive behavioral testing in the R6/2 mouse model of Huntington's disease shows no benefit from CoQ10 or minocycline. PloS one 20100101
Emulsification of coenzyme Q10 using gum arabic increases bioavailability in rats and human and improves food-processing suitability. Journal of nutritional science and vitaminology 20100101
Beneficial effects of a Q-ter based nutritional mixture on functional performance, mitochondrial function, and oxidative stress in rats. PloS one 20100101
Coenzyme Q10 attenuated DMH-induced precancerous lesions in SD rats. Journal of nutritional science and vitaminology 20100101
Coenzyme Q10 treatment ameliorates acute cisplatin nephrotoxicity in mice. Toxicology 20100101
Enhancement of shortening velocity, power, and acto-myosin crossbridge (CB) kinetics following long-term treatment with propionyl-L-carnitine, coenzyme Q10, and omega-3 fatty acids in BIO TO-2 cardiomyopathic Syrian hamsters papillary muscle. BioFactors (Oxford, England) 20100101
Positive correlation between maternal serum coenzyme Q10 levels and infant birth weight. BioFactors (Oxford, England) 20100101
Oxidative stress in Niemann-Pick disease, type C. Molecular genetics and metabolism 20100101
Treatment of CoQ(10) deficient fibroblasts with ubiquinone, CoQ analogs, and vitamin C: time- and compound-dependent effects. PloS one 20100101
Bezafibrate induced increase in mitochondrial electron transport chain complex IV activity in human astrocytoma cells: Implications for mitochondrial cytopathies and neurodegenerative diseases. BioFactors (Oxford, England) 20100101
Exogenous coenzyme Q10 modulates MMP-2 activity in MCF-7 cell line as a breast cancer cellular model. Nutrition journal 20100101
[Effect of coenzyme Q10 and taurine on the availability of vitamins in the rat experiment]. Voprosy pitaniia 20100101
[Effect of dietary fats and supplementary coenzyme Q10 on vitamin provision in animals]. Voprosy pitaniia 20100101
Coenzyme Q10 supplementation lowers hepatic oxidative stress and inflammation associated with diet-induced obesity in mice. Biochemical pharmacology 20091201
[Approach to alternative therapies in community pharmacy]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20091201
Self-microemulsifying formulation-based oral solution of coenzyme Q10. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20091201
Mitochondrial-driven ubiquinone enhances extracellular calcium-dependent nitric oxide production and reduces glycochenodeoxycholic acid-induced cell death in hepatocytes. Chemical research in toxicology 20091201
Inhibition of liver fibrosis by solubilized coenzyme Q10: Role of Nrf2 activation in inhibiting transforming growth factor-beta1 expression. Toxicology and applied pharmacology 20091101
The co-encapsulated antioxidant nanoparticles of ellagic acid and coenzyme Q10 ameliorates hyperlipidemia in high fat diet fed rats. Journal of nanoscience and nanotechnology 20091101
Genotoxicity studies of ubidecarenone (coenzyme Q10) manufactured by bacteria fermentation. The Journal of toxicological sciences 20091001
Evaluation of the antioxidant effect of a new functional food enriched with Sideritis euboea in healthy subjects. Journal of medicinal food 20091001
Nutrition management of pediatric patients who have cystic fibrosis. Pediatric clinics of North America 20091001
Oral administration of coenzyme Q(10) prevents cytochrome c release from mitochondria induced by 1-methyl-4-phenylpyridinium ion in mouse brain synaptosomes. Neuroscience letters 20090929
N-acetylcysteine, coenzyme Q10 and superoxide dismutase mimetic prevent mitochondrial cell dysfunction and cell death induced by d-galactosamine in primary culture of human hepatocytes. Chemico-biological interactions 20090914
Nanoliposomes mediate coenzyme Q10 transport and accumulation across human intestinal Caco-2 cell monolayer. Journal of agricultural and food chemistry 20090909
Formulation and evaluation of ubidecarenone transdermal delivery systems. Drug development and industrial pharmacy 20090901
Combined statin/coenzyme Q10 as adjunctive treatment of chronic heart failure. Medical hypotheses 20090901
Gingival vascular damage in atherosclerotic rabbits: hydroxytyrosol and squalene benefits. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090901
Hepatic VLDL assembly is disturbed in a rat model of nonalcoholic fatty liver disease: is there a role for dietary coenzyme Q? Journal of applied physiology (Bethesda, Md. : 1985) 20090901
Preparation of four types of coenzyme Q10/gamma-cyclodextrin supramolecular complexes and comparison of their pharmaceutical properties. Chemical & pharmaceutical bulletin 20090901
Development of a new high performance liquid chromatography method for measurement of coenzyme Q10 in healthy blood plasma. Saudi medical journal 20090901
Plasma levels of vitamins A and E, coenzyme Q10, and anti-ox-LDL antibody titer in children treated with an elimination diet due to food hypersensitivity. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20090901
Naturally occurring antioxidant nutrients reduce inflammatory response in mice. European journal of pharmacology 20090801
Coenzyme Q(10) is decreased in fibroblasts of patients with methylmalonic aciduria but not in mevalonic aciduria. Journal of inherited metabolic disease 20090801
Gene expression profiling of aging in multiple mouse strains: identification of aging biomarkers and impact of dietary antioxidants. Aging cell 20090801
Electron transfer mediators and other metabolites and cofactors in the treatment of mitochondrial dysfunction. Nutrition reviews 20090801
Development of a new method to preserve caprine cauda epididymal spermatozoa in-situ at -10 degrees C with electrolyte free medium. Journal of assisted reproduction and genetics 20090801
Efficacy of coenzyme Q10 on semen parameters, sperm function and reproductive hormones in infertile men. The Journal of urology 20090701
Biosynthesis and bioproduction of coenzyme Q10 by yeasts and other organisms. Biotechnology and applied biochemistry 20090622
From protons to OXPHOS supercomplexes and Alzheimer's disease: structure-dynamics-function relationships of energy-transducing membranes. Biochimica et biophysica acta 20090601
Combination therapy with coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson's and Huntington's diseases. Journal of neurochemistry 20090601
A capillary electrophoretic system based on a novel microemulsion for the analysis of coenzyme Q10 in human plasma by electrokinetic chromatography. Electrophoresis 20090601
Malondialdehyde and coenzyme Q10 in platelets and serum in type 2 diabetes mellitus: correlation with glycemic control. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20090601
Effect of coenzyme Q10 on cutaneous healing in skin-incised mice. Archives of pharmacal research 20090601
Topical use of coenzyme Q10-loaded liposomes coated with trimethyl chitosan: tolerance, precorneal retention and anti-cataract effect. International journal of pharmaceutics 20090508
Characterization of cellular uptake and distribution of coenzyme Q10 and vitamin E in PC12 cells. The Journal of nutritional biochemistry 20090501
Coenzyme Q10 distribution in blood is altered in patients with fibromyalgia. Clinical biochemistry 20090501
Enhanced production of CoQ10 by newly isolated Sphingomonas sp. ZUTEO3 with a coupled fermentation-extraction process. Journal of industrial microbiology & biotechnology 20090501
Coenzyme Q10 improves endothelial dysfunction in statin-treated type 2 diabetic patients. Diabetes care 20090501
Efficacy of Ginkgolide B in the prophylaxis of migraine with aura. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20090501
Comprehensive high-performance liquid chromatographic method for the measurements of lipophilic antioxidants in human plasma. Journal of chromatography. A 20090410
Coenzyme Q10 in the human retina. Investigative ophthalmology & visual science 20090401
Contribution of nitric oxide, superoxide anion, and peroxynitrite to activation of mitochondrial apoptotic signaling in hippocampal CA3 subfield following experimental temporal lobe status epilepticus. Epilepsia 20090401
Assessment of mitochondrial respiratory chain function in hyperphenylalaninaemia. Journal of inherited metabolic disease 20090401
Coenzyme Q10 and alpha-tocopherol protect against amitriptyline toxicity. Toxicology and applied pharmacology 20090315
Effect of Coenzyme Q(10), Riboflavin and Niacin on Tamoxifen treated postmenopausal breast cancer women with special reference to blood chemistry profiles. Breast cancer research and treatment 20090301
Oxidative stress involvement in alpha-synuclein oligomerization in Parkinson's disease cybrids. Antioxidants & redox signaling 20090301
Coenzyme Q supports distinct developmental processes in Caenorhabditis elegans. Mechanisms of ageing and development 20090301
Clinical and biochemical effects of coenzyme Q(10), vitamin E, and selenium supplementation to psoriasis patients. Nutrition (Burbank, Los Angeles County, Calif.) 20090301
Cystoid macular edema in a patient with chronic progressive external ophthalmoplegia with mitochondrial myopathy. Ophthalmic genetics 20090301
ETFDH mutations, CoQ10 levels, and respiratory chain activities in patients with riboflavin-responsive multiple acyl-CoA dehydrogenase deficiency. Neuromuscular disorders : NMD 20090301
Comparison of bioavailability of two ubidecarenone products in healthy Korean volunteers. International journal of clinical pharmacology and therapeutics 20090301
Coq10, a mitochondrial coenzyme Q binding protein, is required for proper respiration in Schizosaccharomyces pombe. The FEBS journal 20090201
Biological and pharmacological activities of squalene and related compounds: potential uses in cosmetic dermatology. Molecules (Basel, Switzerland) 20090123
The influence of physiological and surgical menopause on coronary heart disease risk markers. Menopause (New York, N.Y.) 20090101
Coenzyme Q10 diminishes ischemia-reperfusion induced apoptosis and nerve injury in rabbit urinary bladder. Neurourology and urodynamics 20090101
Rapid quantitative determination of fat-soluble vitamins and coenzyme Q-10 in human serum by reversed phase ultra-high pressure liquid chromatography with UV detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090101
How do you treat patients with myalgia who take statins? Current atherosclerosis reports 20090101
Applying the Milwaukee protocol to treat canine rabies in Equatorial Guinea. Scandinavian journal of infectious diseases 20090101
Metabolic cardiology: the missing link in cardiovascular disease. Alternative therapies in health and medicine 20090101
Pro-oxidant mitochondrial matrix-targeted ubiquinone MitoQ10 acts as anti-oxidant at retarded electron transport or proton pumping within Complex I. The international journal of biochemistry & cell biology 20090101
Metabolic cardiology: an integrative strategy in the treatment of congestive heart failure. Alternative therapies in health and medicine 20090101
Paraquat induces oxidative stress, neuronal loss in substantia nigra region and parkinsonism in adult rats: neuroprotection and amelioration of symptoms by water-soluble formulation of coenzyme Q10. BMC neuroscience 20090101
Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease. BMC neuroscience 20090101
Decreased ubiquinone availability and impaired mitochondrial cytochrome oxidase activity associated with statin treatment. Toxicology mechanisms and methods 20090101
Improved survival in patients with end-stage cancer treated with coenzyme Q(10) and other antioxidants: a pilot study. The Journal of international medical research 20090101
Co-enzyme Q10, riboflavin and niacin supplementation on alteration of DNA repair enzyme and DNA methylation in breast cancer patients undergoing tamoxifen therapy. The British journal of nutrition 20081201
Validation and application of an HPLC-EC method for analysis of coenzyme Q10 in blood platelets. Biomedical chromatography : BMC 20081201
Mechanism of the neuroprotective role of coenzyme Q10 with or without L-dopa in rotenone-induced parkinsonism. Neuropharmacology 20081201
The role of oral coenzyme Q10 in patients undergoing coronary artery bypass graft surgery. Journal of cardiothoracic and vascular anesthesia 20081201
Supplementation with an antioxidant cocktail containing coenzyme Q prevents plasma oxidative damage induced by soccer. European journal of applied physiology 20081101
Coenzyme Q10 supplementation rescues renal disease in Pdss2kd/kd mice with mutations in prenyl diphosphate synthase subunit 2. American journal of physiology. Renal physiology 20081101
Effect of antioxidant phytochemicals on the hepatic tumor promoting activity of 3,3',4,4'-tetrachlorobiphenyl (PCB-77). Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081101
The beneficial effect of coenzyme Q10 and lipoic acid on obstructive bladder dysfunction in the rabbit. The Journal of urology 20081101
Genetic predisposition to statin myopathy. Current opinion in rheumatology 20081101
Pituitary adenylate cyclase-activating polypeptide attenuates streptozotocin-induced apoptotic death of RIN-m5F cells through regulation of Bcl-2 family protein mRNA expression. The FEBS journal 20081101
Coenzyme Q10: an independent predictor of mortality in chronic heart failure. Journal of the American College of Cardiology 20081028
Redox state of coenzyme Q10 determines its membrane localization. The journal of physical chemistry. B 20081009
Reducing exercise-induced muscular injury in kendo athletes with supplementation of coenzyme Q10. The British journal of nutrition 20081001
Effect of water-soluble coenzyme Q10 on noise-induced hearing loss in guinea pigs. Acta oto-laryngologica 20081001
Complementary and alternative treatments for childhood headaches. Current pain and headache reports 20081001
Lipid storage myopathies. Current opinion in neurology 20081001
Evaluation of antioxidant systems (coenzyme Q10 and total antioxidant capacity) in morbid obesity before and after biliopancreatic diversion. Metabolism: clinical and experimental 20081001
Effect of energy compound on skeletal muscle strain injury and regeneration in rats. Industrial health 20081001
The mitochondrial phosphate carrier interacts with cyclophilin D and may play a key role in the permeability transition. The Journal of biological chemistry 20080926
Decreased total serum coenzyme-Q10 concentrations: a longitudinal study in children with cystic fibrosis. The Journal of pediatrics 20080901
Screening of detergents for solubilization, purification and crystallization of membrane proteins: a case study on succinate:ubiquinone oxidoreductase from Escherichia coli. Acta crystallographica. Section F, Structural biology and crystallization communications 20080901
Ask the doctor. Why don't you ever tell your readers that everyone who takes a statin to lower cholesterol should be taking coenzyme Q(10) too? Harvard heart letter : from Harvard Medical School 20080901
Interaction of coenzyme Q10 with the intestinal drug transporter P-glycoprotein. Journal of agricultural and food chemistry 20080827
Coenzyme Q10 protects retinal cells against oxidative stress in vitro and in vivo. Brain research 20080821
Methyl group dynamics in glassy, polycrystalline, and liquid coenzyme Q10 studied by quasielastic neutron scattering. The Journal of chemical physics 20080821
Bioavailability of water-soluble CoQ10 in beagle dogs. Journal of pharmaceutical and biomedical analysis 20080805
Hemodynamic effects of fenofibrate and coenzyme Q10 in type 2 diabetic subjects with left ventricular diastolic dysfunction. Diabetes care 20080801
Functional characterization of human COQ4, a gene required for Coenzyme Q10 biosynthesis. Biochemical and biophysical research communications 20080718
Effect of co-enzyme Q10 and alpha-lipoic acid on response of rabbit urinary bladder to repetitive stimulation and in vitro ischemia. Urology 20080701
Lipidomic analysis and electron transport chain activities in C57BL/6J mouse brain mitochondria. Journal of neurochemistry 20080701
Environmental contaminants and redox status of coenzyme Q10 and vitamin E in Inuit from Nunavik. Metabolism: clinical and experimental 20080701
Lapaquistat acetate, a squalene synthase inhibitor, changes macrophage/lipid-rich coronary plaques of hypercholesterolaemic rabbits into fibrous lesions. British journal of pharmacology 20080701
The effect of coenzyme Q10 on the pharmacokinetic parameters of theophylline. Archives of pharmacal research 20080701
Atorvastatin-induced changes in plasma coenzyme q10 and brain natriuretic peptide in patients with coronary artery disease. International heart journal 20080701
Activity of 1,4-benzoquinones against formosan subterranean termites (Coptotermes formosanus). Journal of agricultural and food chemistry 20080611
Respiratory chain dysfunction and oxidative stress correlate with severity of primary CoQ10 deficiency. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080601
Voltammetric determination of coenzyme Q10 in pharmaceutical dosage forms. Bioelectrochemistry (Amsterdam, Netherlands) 20080601
Beneficial effect of coenzyme Q10 on increased oxidative and nitrative stress and inflammation and individual metabolic components developing in a rat model of metabolic syndrome. Journal of pharmacological sciences 20080601
Coenzyme Q(10) and alpha-lipoic acid supplementation in diabetic rats: conduction velocity distributions. Methods and findings in experimental and clinical pharmacology 20080601
Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, placebo-controlled trial. Movement disorders : official journal of the Movement Disorder Society 20080515
Augmented antioxidant status in Tamoxifen treated postmenopausal women with breast cancer on co-administration with Coenzyme Q10, Niacin and Riboflavin. Cancer chemotherapy and pharmacology 20080501
Comparison of effects of pitavastatin and atorvastatin on plasma coenzyme Q10 in heterozygous familial hypercholesterolemia: results from a crossover study. Clinical pharmacology and therapeutics 20080501
The in-depth evaluation of suspected mitochondrial disease. Molecular genetics and metabolism 20080501
Myopathy associated with chronic orlistat consumption: a case report. Neuromuscular disorders : NMD 20080501
Seasonal mercury exposure and oxidant-antioxidant status of James Bay sport fishermen. Metabolism: clinical and experimental 20080501
The mitochondrial free radical theory of ageing--where do we stand? Frontiers in bioscience : a journal and virtual library 20080501
[Effects of coenzyme Q10 or combined with micronutrients on antioxidant defense system in rats]. Wei sheng yan jiu = Journal of hygiene research 20080501
Coenzyme Q10 protect against ischemia/reperfusion induced biochemical and functional changes in rabbit urinary bladder. Molecular and cellular biochemistry 20080401
I need to take statins to lower my cholesterol, but the drug I tried gave me terrible leg cramps. Is there anything I can take to avoid these cramps, or do I have to find another way to lower my cholesterol? Heart advisor 20080401
Rosuvastatin in older patients with systolic heart failure. The New England journal of medicine 20080320
CABC1 gene mutations cause ubiquinone deficiency with cerebellar ataxia and seizures. American journal of human genetics 20080303
ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. American journal of human genetics 20080303
Therapeutic effects of coenzyme Q10 (CoQ10) and reduced CoQ10 in the MPTP model of Parkinsonism. Journal of neurochemistry 20080301
Purified and surfactant-free coenzyme Q10-loaded biodegradable nanoparticles. International journal of pharmaceutics 20080204
Coenzyme Q10 in patients undergoing CABG: Effect of statins and nutritional supplementation. Nutrition, metabolism, and cardiovascular diseases : NMCD 20080201
Coenzyme Q10 as a potent compound that inhibits Cdt1-geminin interaction. Biochimica et biophysica acta 20080201
Coenzyme Q10 attenuates beta-amyloid pathology in the aged transgenic mice with Alzheimer presenilin 1 mutation. Journal of molecular neuroscience : MN 20080201
[Isolation, characterization and fermentation condition of coenzyme Q10 producing strain with solanesol as precursor]. Wei sheng wu xue bao = Acta microbiologica Sinica 20080201
Supplementation of coenzyme Q10 and alpha-tocopherol lowers glycated hemoglobin level and lipid peroxidation in pancreas of diabetic rats. Nutrition research (New York, N.Y.) 20080201
Analysis of CoQ10 in rat serum by ultra-performance liquid chromatography mass spectrometry after oral administration. Journal of pharmaceutical and biomedical analysis 20080107
[Pigmented basidiomycete yeasts are a promising source of carotenoids and ubiquinone Q10]. Mikrobiologiia 20080101
Endogenous protective mechanisms in remodeling of rat heart mitochondrial membranes in the acute phase of streptozotocin-induced diabetes. Physiological research 20080101
The effect of antioxidant treatment and NOS inhibition on the incidence of ischemia-induced arrhythmias in the diabetic rat heart. Physiological research 20080101
Subchronic oral toxicity of ubiquinol in rats and dogs. International journal of toxicology 20080101
Anti-angiogenic potential of CoenzymeQ10, riboflavin and niacin in breast cancer patients undergoing tamoxifen therapy. Vascular pharmacology 20080101
Normalization of ejection fraction and resolution of symptoms in chronic severe heart failure is possible with modern medical therapy: clinical observations in 11 patients. American journal of therapeutics 20080101
Coenzyme Q10 administration suppresses both oxidative and antioxidative markers in hemodialysis patients. Blood purification 20080101
Effects of testosterone on antioxidant systems in male secondary hypogonadism. Journal of andrology 20080101
[Antioxidants prevent experimental hemiparkinsonism in rats]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20080101
Toluene and P-xylene mixture exerts antagonistic effect on lipid peroxidation in vitro. International journal of occupational medicine and environmental health 20080101
Assessment of neuroprotection in the retina with DARC. Progress in brain research 20080101
Rational basis for the development of coenzyme Q10 as a neurotherapeutic agent for retinal protection. Progress in brain research 20080101
Functional role of coenzyme Q in the energy coupling of NADH-CoQ oxidoreductase (Complex I): stabilization of the semiquinone state with the application of inside-positive membrane potential to proteoliposomes. BioFactors (Oxford, England) 20080101
Effect of CoQ homologues on reactive oxygen generation by mitochondria. BioFactors (Oxford, England) 20080101
NADPH-dependent coenzyme Q reductase is the main enzyme responsible for the reduction of non-mitochondrial CoQ in cells. BioFactors (Oxford, England) 20080101
Positive inotropic effect of coenzyme Q10, omega-3 fatty acids and propionyl-L-carnitine on papillary muscle force-frequency responses of BIO TO-2 cardiomyopathic Syrian hamsters. BioFactors (Oxford, England) 20080101
Antiangiogenic and hypolipidemic activity of coenzyme Q10 supplementation to breast cancer patients undergoing Tamoxifen therapy. BioFactors (Oxford, England) 20080101
Coenzyme Q10 and oxidative imbalance in Down syndrome: biochemical and clinical aspects. BioFactors (Oxford, England) 20080101
Functions of coenzyme Q10 in inflammation and gene expression. BioFactors (Oxford, England) 20080101
Plasma and thrombocyte levels of coenzyme Q10 in children with Smith-Lemli-Opitz syndrome (SLOS) and the influence of HMG-CoA reductase inhibitors. BioFactors (Oxford, England) 20080101
Supplementation with CoQ10 lowers age-related (ar) NOX levels in healthy subjects. BioFactors (Oxford, England) 20080101
arNOX activity of saliva as a non-invasive measure of coenzyme Q10 response in human trials. BioFactors (Oxford, England) 20080101
Aging skin is functionally anaerobic: importance of coenzyme Q10 for anti aging skin care. BioFactors (Oxford, England) 20080101
Oxidative stress status in liver mitochondria and lymphocyte DNA damage of atherosclerotic rabbits supplemented with water soluble coenzyme Q10. BioFactors (Oxford, England) 20080101
[Metabolic therapy for early treatment of age-related macular degeneration]. Orvosi hetilap 20071202
Effects of CoQ10 supplementation on plasma lipoprotein lipid, CoQ10 and liver and muscle enzyme levels in hypercholesterolemic patients treated with atorvastatin: a randomized double-blind study. Atherosclerosis 20071201
Coenzyme Q10 (ubiquinol-10) supplementation improves oxidative imbalance in children with trisomy 21. Pediatric neurology 20071201
Increase of bioavailability of coenzyme Q(10) and vitamin E. Journal of medicinal food 20071201
Protective effect of coenzyme Q10-loaded liposomes on the myocardium in rabbits with an acute experimental myocardial infarction. Pharmaceutical research 20071101
Current prospects for the production of coenzyme Q10 in microbes. Trends in biotechnology 20071101
Effect of coenzyme Q(10) supplementation on simvastatin-induced myalgia. The American journal of cardiology 20071101
Effect of lifelong coenzyme Q10 supplementation on age-related oxidative stress and mitochondrial function in liver and skeletal muscle of rats fed on a polyunsaturated fatty acid (PUFA)-rich diet. The journals of gerontology. Series A, Biological sciences and medical sciences 20071101
[Effects of coenzyme Q10 supplementation on liver mitochondrial function and aerobic capacity in adolescent athletes]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20071101
Effects of coenzyme Q10 on the heart ultrastructure and nitric oxide synthase during hyperthyroidism. The Chinese journal of physiology 20071031
Serum cholesterol, use of lipid-lowering drugs, and risk of Parkinson disease. Movement disorders : official journal of the Movement Disorder Society 20071015
Coenzyme Q 10 and cardiovascular risk factors in idiopathic sudden sensorineural hearing loss patients. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20071001
Functional connections and pathways of coenzyme Q10-inducible genes: an in-silico study. IUBMB life 20071001
Mechanisms of oxidative modification of low density lipoproteins under conditions of oxidative and carbonyl stress. Biochemistry. Biokhimiia 20071001
[Oxidative stress]. Revue medicale de Liege 20071001
Reduced mitochondrial coenzyme Q10 levels in HepG2 cells treated with high-dose simvastatin: a possible role in statin-induced hepatotoxicity? Toxicology and applied pharmacology 20070901
Risk of warfarin-related bleeding events and supratherapeutic international normalized ratios associated with complementary and alternative medicine: a longitudinal analysis. Pharmacotherapy 20070901
Future directions in the treatment of Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society 20070901
Cetyl palmitate-based NLC for topical delivery of Coenzyme Q(10) - development, physicochemical characterization and in vitro release studies. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20070801
The myopathic form of coenzyme Q10 deficiency is caused by mutations in the electron-transferring-flavoprotein dehydrogenase (ETFDH) gene. Brain : a journal of neurology 20070801
Controlling the sucrose concentration increases Coenzyme Q10 production in fed-batch culture of Agrobacterium tumefaciens. Applied microbiology and biotechnology 20070801
Modifications of plasma proteome in long-lived rats fed on a coenzyme Q10-supplemented diet. Experimental gerontology 20070801
Antioxidant supplementation enhances the exercise-induced increase in mitochondrial uncoupling protein 3 and endothelial nitric oxide synthase mRNA content in human skeletal muscle. Free radical biology & medicine 20070801
[Statin drugs decrease the plasma level of coenzyme Q10 (ubiquinone) in the organism]. Ideggyogyaszati szemle 20070730
Images in cardiovascular medicine. Mitochondrial cardiomyopathy evaluated with cardiac magnetic resonance. Circulation 20070710
Coenzyme Q10 prevents high glucose-induced oxidative stress in human umbilical vein endothelial cells. European journal of pharmacology 20070702
Inhibition of mitochondrial complex IV leads to secondary loss complex II-III activity: implications for the pathogenesis and treatment of mitochondrial encephalomyopathies. Mitochondrion 20070701
Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q(10) in Parkinson disease. Archives of neurology 20070701
The role of coenzyme Q10 in statin-associated myopathy: a systematic review. Journal of the American College of Cardiology 20070612
Impairment of the mitochondrial respiratory enzyme activity triggers sequential activation of apoptosis-inducing factor-dependent and caspase-dependent signaling pathways to induce apoptosis after spinal cord injury. Journal of neurochemistry 20070601
Ameliorating effect of coenzyme Q10, riboflavin and niacin in tamoxifen-treated postmenopausal breast cancer patients with special reference to lipids and lipoproteins. Clinical biochemistry 20070601
Infantile and pediatric quinone deficiency diseases. Mitochondrion 20070601
Coenzyme Q10 in phenylketonuria and mevalonic aciduria. Mitochondrion 20070601
Coenzyme Q(10)--its role as a prooxidant in the formation of superoxide anion/hydrogen peroxide and the regulation of the metabolome. Mitochondrion 20070601
Coenzyme Q10 in cardiovascular disease. Mitochondrion 20070601
Friedreich's ataxia: coenzyme Q10 and vitamin E therapy. Mitochondrion 20070601
Serum cytokine levels of interleukin-1beta, -6, -8, tumour necrosis factor-alpha and vascular endothelial growth factor in breast cancer patients treated with tamoxifen and supplemented with co-enzyme Q(10), riboflavin and niacin. Basic & clinical pharmacology & toxicology 20070601
Protective effects of antioxidant medications on limb ischemia reperfusion injury. The Journal of surgical research 20070515
NADPH oxidase- and mitochondrion-derived superoxide at rostral ventrolateral medulla in endotoxin-induced cardiovascular depression. Free radical biology & medicine 20070515
Effect of coenzyme q10 on myopathic symptoms in patients treated with statins. The American journal of cardiology 20070515
Cathodic reduction of coenzyme Q10 on glassy carbon electrode in acetic acid-acetonitrile solutions. Bioelectrochemistry (Amsterdam, Netherlands) 20070501
Missense mutation of the COQ2 gene causes defects of bioenergetics and de novo pyrimidine synthesis. Human molecular genetics 20070501
Prevention of anthracycline-induced cardiotoxicity in children: the evidence. European journal of cancer (Oxford, England : 1990) 20070501
Beneficial effects of pro-/antioxidant-based nutraceuticals in the skin rejuvenation techniques. Cellular and molecular biology (Noisy-le-Grand, France) 20070415
Human coenzyme Q10 deficiency. Neurochemical research 20070401
Optimization of culture conditions and scale-up to pilot and plant scales for coenzyme Q10 production by Agrobacterium tumefaciens. Applied microbiology and biotechnology 20070401
Effect of coenzyme Q(10) incorporation on the characteristics of nanoliposomes. The journal of physical chemistry. B 20070308
Up-regulation of plasma membrane-associated redox activities in neuronal cells lacking functional mitochondria. Journal of neurochemistry 20070301
Prenyldiphosphate synthase, subunit 1 (PDSS1) and OH-benzoate polyprenyltransferase (COQ2) mutations in ubiquinone deficiency and oxidative phosphorylation disorders. The Journal of clinical investigation 20070301
[Diagnosis and treatment of hereditary neurological disorders during childhood]. No to hattatsu = Brain and development 20070301
Chronic administration of coenzyme Q10 limits postinfarct myocardial remodeling in rats. Biochemistry. Biokhimiia 20070301
Statin-induced adverse effects and malignant hyperthermia susceptibility: comment on the article by Guis et al. Arthritis and rheumatism 20070215
Beneficial effects of creatine, CoQ10, and lipoic acid in mitochondrial disorders. Muscle & nerve 20070201
Vitamin A potently destabilizes preformed alpha-synuclein fibrils in vitro: implications for Lewy body diseases. Neurobiology of disease 20070201
Effect of coenzyme Q10, riboflavin and niacin on serum CEA and CA 15-3 levels in breast cancer patients undergoing tamoxifen therapy. Biological & pharmaceutical bulletin 20070201
Effects of dietary L-carnitine and coenzyme Q10 at different supplemental ages on growth performance and some immune response in ascites-susceptible broilers. Archives of animal nutrition 20070201
Electron paramagnetic spectroscopic evidence of exercise-induced free radical accumulation in human skeletal muscle. Free radical research 20070201
A randomized clinical trial of coenzyme Q10 and GPI-1485 in early Parkinson disease. Neurology 20070102
Atorvastatin has cardiac safety at intensive cholesterol-reducing protocols for long term, yet its cancer-treatment doses with chemotherapy may cause cardiomyopathy even under coenzyme-Q10 protection. Cell biochemistry and function 20070101
Coenzyme Q10: a review of its promise as a neuroprotectant. CNS spectrums 20070101
Beta-cell function in individuals carrying the mitochondrial tRNA leu (UUR) mutation. Pancreas 20070101
A pilot clinical trial of the effects of coenzyme Q10 on chronic tinnitus aurium. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20070101
Since my heart attack two years ago I have been taking a stain and my cholesterol numbers are excellent. My chiropractor suggests I also should be taking CoQ10 for even better cholesterol health. Does that make sense? DukeMedicine healthnews 20070101
Protective role of melatonin and coenzyme Q10 in ochratoxin A toxicity in rat liver and kidney. International journal of toxicology 20070101
Enrichment of coenzyme Q10 in plasma and blood cells: defense against oxidative damage. International journal of biological sciences 20070101
ECTO-NOX target for the anticancer isoflavene phenoxodiol. Oncology research 20070101
Do N-acetylcystein, beta-glucan, and coenzyme Q10 mollify myocardial ischemia-reperfusion injury? The heart surgery forum 20070101
The clinical application of metabolic therapy for cardiovascular disease. Heart, lung & circulation 20070101
[Antioxidant and prooxidant action of nitric oxide donors and metabolites]. Biofizika 20070101
Coenzyme Q10 concentration in the plasma of children suffering from acute lymphoblastic leukaemia before and during induction treatment. BioFactors (Oxford, England) 20070101
Retinal damage caused by high intraocular pressure-induced transient ischemia is prevented by coenzyme Q10 in rat. International review of neurobiology 20070101
Simvastatin decreased coenzyme Q in the left ventricle and skeletal muscle but not in the brain and liver in L-NAME-induced hypertension. Physiological research 20070101
[Experimental study of the effects of metabolic drugs on exercise tolerance]. Voprosy kurortologii, fizioterapii, i lechebnoi fizicheskoi kultury 20070101
Effect of Coenzyme Q10 supplementation on exercise-induced muscular injury of rats. Exercise immunology review 20070101
Critical assessment of various techniques for the extraction of carotenoids and co-enzyme Q10 from the Thraustochytrid strain ONC-T18. Journal of agricultural and food chemistry 20061227
Biochemical characterization of the decaprenyl diphosphate synthase of Rhodobacter sphaeroides for coenzyme Q10 production. Applied microbiology and biotechnology 20061201
Respiratory system of Gluconacetobacter diazotrophicus PAL5. Evidence for a cyanide-sensitive cytochrome bb and cyanide-resistant cytochrome ba quinol oxidases. Biochimica et biophysica acta 20061201
A role for copper in biological time-keeping. Journal of inorganic biochemistry 20061201
Oxidant/antioxidant interactions of nicotine, Coenzyme Q10, Pycnogenol and phytoestrogens in oral periosteal fibroblasts and MG63 osteoblasts. Steroids 20061201
Oxidative burden in prediabetic and diabetic individuals: evidence from plasma coenzyme Q(10). Diabetic medicine : a journal of the British Diabetic Association 20061201
Leigh syndrome with nephropathy and CoQ10 deficiency due to decaprenyl diphosphate synthase subunit 2 (PDSS2) mutations. American journal of human genetics 20061201
Serum cholesterol levels and the risk of Parkinson's disease. American journal of epidemiology 20061115
Mitochondrial myopathies. Current opinion in rheumatology 20061101
Decreased coenzyme Q10 concentration in plasma of children with cystic fibrosis. Journal of pediatric gastroenterology and nutrition 20061101
Structure of electron transfer flavoprotein-ubiquinone oxidoreductase and electron transfer to the mitochondrial ubiquinone pool. Proceedings of the National Academy of Sciences of the United States of America 20061031
Amplification of 1-deoxy-D-xyluose 5-phosphate (DXP) synthase level increases coenzyme Q10 production in recombinant Escherichia coli. Applied microbiology and biotechnology 20061001
Determination of coenzyme Q10 in human seminal plasma by high-performance liquid chromatography and its clinical application. Biomedical chromatography : BMC 20061001
Metallothioneins 1 and 2 attenuate peroxynitrite-induced oxidative stress in Parkinson disease. Experimental biology and medicine (Maywood, N.J.) 20061001
[Case of drug-induced pneumonitis associated with a dietary supplement containing CoQ10]. Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20061001
HPLC method for simultaneous determination of retinol, alpha-tocopherol and coenzyme Q10 in human plasma. Journal of pharmaceutical and biomedical analysis 20060918
Coenzyme Q10 production in recombinant Escherichia coli strains engineered with a heterologous decaprenyl diphosphate synthase gene and foreign mevalonate pathway. Metabolic engineering 20060901
Oxidative stress in skin fibroblasts cultures of patients with Huntington's disease. Neurochemical research 20060901
Optimization in the preparation of coenzyme Q10 nanoliposomes. Journal of agricultural and food chemistry 20060823
SANDO: two novel mutations in POLG1 gene. Neuromuscular disorders : NMD 20060801
Coenzyme Q10 modulates cognitive impairment against intracerebroventricular injection of streptozotocin in rats. Behavioural brain research 20060715
Cerebellar ataxia with coenzyme Q10 deficiency: diagnosis and follow-up after coenzyme Q10 supplementation. Journal of the neurological sciences 20060715
Neither plasma coenzyme Q10 concentration, nor its decline during pravastatin therapy, is linked to recurrent cardiovascular disease events: a prospective case-control study from the LIPID study. Atherosclerosis 20060701
A rapid and sensitive LC-MS/MS method for determination of coenzyme Q10 in tobacco (Nicotiana tabacum L.) leaves. Journal of separation science 20060701
Complex-1 activity and 18F-DOPA uptake in genetically engineered mouse model of Parkinson's disease and the neuroprotective role of coenzyme Q10. Brain research bulletin 20060615
Controlled release of a self-emulsifying formulation from a tablet dosage form: stability assessment and optimization of some processing parameters. International journal of pharmaceutics 20060606
Dose ranging and efficacy study of high-dose coenzyme Q10 formulations in Huntington's disease mice. Biochimica et biophysica acta 20060601
Pre-operative preparation for cardiac surgery utilising a combination of metabolic, physical and mental therapy. Heart, lung & circulation 20060601
'Natural' or alternative medications for migraine prevention. Headache 20060601
[Myocardial dysfunction]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20060601
Ubiquinone (coenzyme Q10) binding sites: low dielectric constant of the gate prevents the escape of the semiquinone. FEBS letters 20060515
Effects of menstrual cycle and oral contraceptive use on serum levels of lipid-soluble antioxidants. American journal of obstetrics and gynecology 20060501
Modification of biochemical parameters of gentamicin nephrotoxicity by coenzyme Q10 and green tea in rats. Indian journal of experimental biology 20060501
[Recent changes in concepts of antioxidant treatment]. Orvosi hetilap 20060423
Chemotherapy induces an increase in coenzyme Q10 levels in cancer cell lines. Free radical biology & medicine 20060415
[The role of antioxidants in prevention]. Orvosi hetilap 20060402
Protection against radiation-induced oxidative stress in cultured human epithelial cells by treatment with antioxidant agents. International journal of radiation oncology, biology, physics 20060401
Effects of fenofibrate therapy on plasma ubiquinol-10 and ubiquinone-10 levels in Japanese patients with hyperlipidemia and type 2 diabetes mellitus. Pharmacotherapy 20060401
Chinese red rice depletes muscle coenzyme Q10 and maintains muscle damage after discontinuation of statin treatment. Journal of the American Geriatrics Society 20060401
Evaluation of the mutagenic potential of ubidecarenone using three short-term assays. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060301
Combination therapy using minocycline and coenzyme Q10 in R6/2 transgenic Huntington's disease mice. Biochimica et biophysica acta 20060301
Cryptococcus bestiolae and Cryptococcus dejecticola, two new yeast species isolated from frass of the litchi fruit borer Conopomorpha sinensis Bradley. FEMS yeast research 20060301
Attenuation of cocaine and methamphetamine neurotoxicity by coenzyme Q10. Neurochemical research 20060301
Anti-inflammatory effects of CoQ10 and colorless carotenoids. Journal of cosmetic dermatology 20060301
Metabolic engineering of coenzyme Q by modification of isoprenoid side chain in plant. FEBS letters 20060206
Reduced coenzyme Q10 supplementation decelerates senescence in SAMP1 mice. Experimental gerontology 20060201
Coenzyme Q concentration and total antioxidant capacity of human milk at different stages of lactation in mothers of preterm and full-term infants. Free radical research 20060201
A mutation in para-hydroxybenzoate-polyprenyl transferase (COQ2) causes primary coenzyme Q10 deficiency. American journal of human genetics 20060201
Effect of coenzyme Q10 intake on endogenous coenzyme Q content, mitochondrial electron transport chain, antioxidative defenses, and life span of mice. Free radical biology & medicine 20060201
Aging and antioxidants. Fruits and vegetables are powerful armor. Advance for nurse practitioners 20060201
Coenzyme Q10 deficiency and isolated myopathy. Neurology 20060124
Selenium and antioxidant vitamin status of elderly German women. European journal of clinical nutrition 20060101
Effect of coenzyme Q10 and vitamin E on brain energy metabolism in the animal model of Huntington's disease. Neurochemistry international 20060101
Effect of coenzyme Q10 on catalase activity and other antioxidant parameters in streptozotocin-induced diabetic rats. Biological trace element research 20060101
Supplemental conditionally essential nutrients in cardiovascular disease therapy. The Journal of cardiovascular nursing 20060101
Determination of coenzyme Q10 in over-the-counter dietary supplements by high-performance liquid chromatography with coulometric detection. Journal of AOAC International 20060101
Friedreich's ataxia: from disease mechanisms to therapeutic interventions. Antioxidants & redox signaling 20060101
Coenzyme Q(10) provides neuroprotection in iron-induced apoptosis in dopaminergic neurons. Journal of molecular neuroscience : MN 20060101
[The influence of phospholipids food and antioxidant at patients with hypertension]. Voprosy pitaniia 20060101
[Experience in coenzyme Q10 application in complex therapy of coronary heart disease with dyslipidemia]. Klinicheskaia meditsina 20060101
Effect of ezetimibe and/or simvastatin on coenzyme Q10 levels in plasma: a randomised trial. Drug safety 20060101
[Combination treatment with coenzyme Q10 and simvastatin in patients with coronary atherosclerosis]. Kardiologiia 20060101
[Hormonal status of tobacco variety Samsun NN exposed to synthetic coenzyme Q10 (ubiquinone 50) and TMV infection]. Izvestiia Akademii nauk. Seriia biologicheskaia 20060101
Coenzyme Q10 concentration in plasma and blood cells: what about diurnal changes? BioFactors (Oxford, England) 20060101
Effect of atorvastatin withdrawal on circulating coenzyme Q10 concentration in patients with hypercholesterolemia. BioFactors (Oxford, England) 20060101
The Saccharomyces cerevisiae COQ10 gene encodes a START domain protein required for function of coenzyme Q in respiration. The Journal of biological chemistry 20051230
Daily profile of plasma %CoQ10 level, a biomarker of oxidative stress, in patients with diabetes manifesting postprandial hyperglycaemia. Acta diabetologica 20051201
Localization of coenzyme Q10 in the center of a deuterated lipid membrane by neutron diffraction. Biochimica et biophysica acta 20051115
CoQ10 therapy attenuates amyloid beta-peptide toxicity in brain mitochondria isolated from aged diabetic rats. Experimental neurology 20051101
Muscle coenzyme Q10 level in statin-related myopathy. Archives of neurology 20051101
Age-associated changes in protein oxidation and proteasome activities in rat brain: modulation by antioxidants. Biochemical and biophysical research communications 20051021
Transient formation of a neutral ubisemiquinone radical and subsequent intramolecular electron transfer to pyrroloquinoline quinone in the Escherichia coli membrane-integrated glucose dehydrogenase. Biochemistry 20051018
Protective effect of coenzyme Q10 in simvastatin and gemfibrozil induced rhabdomyolysis in rats. Indian journal of experimental biology 20051001
Effects of dietary coenzyme Q10 supplementation on hepatic mitochondrial function and the activities of respiratory chain-related enzymes in ascitic broiler chickens. British poultry science 20051001
Electron transfer within complex II. Succinate:ubiquinone oxidoreductase of Escherichia coli. The Journal of biological chemistry 20050930
An improved synthesis of the 'miracle nutrient' coenzyme Q10. Organic letters 20050915
Infantile encephalomyopathy and nephropathy with CoQ10 deficiency: a CoQ10-responsive condition. Neurology 20050823
Styrene and ethylene glycol have a synergetic effect on lipid peroxidation that is better protected than repaired by CoQ10. Toxicology in vitro : an international journal published in association with BIBRA 20050801
Ubiquinone synthesis in mitochondrial and microsomal subcellular fractions of Pneumocystis spp.: differential sensitivities to atovaquone. Eukaryotic cell 20050801
Coenzyme Q10 protects from aging-related oxidative stress and improves mitochondrial function in heart of rats fed a polyunsaturated fatty acid (PUFA)-rich diet. The journals of gerontology. Series A, Biological sciences and medical sciences 20050801
Effects of metabolic modifiers such as carnitines, coenzyme Q10, and PUFAs against different forms of neurotoxic insults: metabolic inhibitors, MPTP, and methamphetamine. Annals of the New York Academy of Sciences 20050801
Effect of ubiquinone Q(10) and antioxidant vitamins on free radical oxidation of phospholipids in biological membranes of rat liver. Bulletin of experimental biology and medicine 20050801
Possible role of ubiquinone in the treatment of massive hypertriglyceridemia resistant to PUFA and fibrates. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20050701
Potential role of ubiquinone (coenzyme Q10) in pediatric cardiomyopathy. Clinical nutrition (Edinburgh, Scotland) 20050601
Mitochondrial membrane depolarization and the selective death of dopaminergic neurons by rotenone: protective effect of coenzyme Q10. Journal of neurochemistry 20050601
[Role of mitochondrial dysfunction in pathogenesis of diabetic microangiopathy]. Nihon rinsho. Japanese journal of clinical medicine 20050601
Energy-modulating vitamins--a new combinatorial therapy prevents cancer cachexia in rat mammary carcinoma. The British journal of nutrition 20050601
Molecular clues into the pathogenesis of statin-mediated muscle toxicity. Muscle & nerve 20050501
Gene expression profiling studies of aging in cardiac and skeletal muscles. Cardiovascular research 20050501
Prospective observational study of treatments for unexplained chronic fatigue. The Journal of clinical psychiatry 20050501
Migraine preventive therapy: current and emerging treatment options. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20050501
Neuroprotective role of coenzyme Q10 against dysfunction of mitochondrial respiratory chain at rostral ventrolateral medulla during fatal mevinphos intoxication in the rat. Annals of the New York Academy of Sciences 20050501
Combined efficacy of tamoxifen and coenzyme Q10 on the status of lipid peroxidation and antioxidants in DMBA induced breast cancer. Molecular and cellular biochemistry 20050501
Preformed beta-amyloid fibrils are destabilized by coenzyme Q10 in vitro. Biochemical and biophysical research communications 20050429
Batch and fed-batch production of coenzyme Q10 in recombinant Escherichia coli containing the decaprenyl diphosphate synthase gene from Gluconobacter suboxydans. Applied microbiology and biotechnology 20050401
Effect of a nutritional supplement containing vitamin E, selenium, vitamin c and coenzyme Q10 on serum PSA in patients with hormonally untreated carcinoma of the prostate: a randomised placebo-controlled study. European urology 20050401
Systemic markers of lipid peroxidation and antioxidants in patients with nonalcoholic Fatty liver disease. The American journal of gastroenterology 20050401
Coenzyme q10 confers cardiovascular protection against acute mevinphos intoxication by ameliorating bioenergetic failure and hypoxia in the rostral ventrolateral medulla of the rat. Shock (Augusta, Ga.) 20050401
Effects of simvastatin on blood lipids, vitamin E, coenzyme Q10 levels and left ventricular function in humans. European journal of clinical investigation 20050401
Maternal antioxidant supplementation does not reduce the incidence of phenytoin-induced cleft lip and related malformations in rats. Birth defects research. Part B, Developmental and reproductive toxicology 20050401
Effect of coenzyme Q10 on warfarin hydroxylation in rat and human liver microsomes. Current drug metabolism 20050401
[Effects of culture conditions on coenzyme Q10 production by Rhizobium radiobacter by metabolic flux analysis]. Wei sheng wu xue bao = Acta microbiologica Sinica 20050401
Metallothionein-mediated neuroprotection in genetically engineered mouse models of Parkinson's disease. Brain research. Molecular brain research 20050324
Concurrent administration of coenzyme Q10 and alpha-tocopherol improves learning in aged mice. Free radical biology & medicine 20050315
Ubidecarenone nanoemulsified composite systems. International journal of pharmaceutics 20050303
Endothelium-ameliorating effects of statin therapy and coenzyme Q10 reductions in chronic heart failure. Atherosclerosis 20050301
A placebo-controlled screening trial of olanzapine, valproate, and coenzyme Q10/L-carnitine for the treatment of cocaine dependence. Addiction (Abingdon, England) 20050301
Regional permeability of coenzyme Q10 in isolated rat gastrointestinal tracts. Die Pharmazie 20050301
Influence of coenzyme Q(10) and cerivastatin on the flow-mediated vasodilation of the brachial artery: results of the ENDOTACT study. International journal of cardiology 20050227
Augmented efficacy of tamoxifen in rat breast tumorigenesis when gavaged along with riboflavin, niacin, and CoQ10: effects on lipid peroxidation and antioxidants in mitochondria. Chemico-biological interactions 20050227
Biological variation of coenzyme Q10. Clinical chemistry 20050201
Isolated mitochondrial myopathy associated with muscle coenzyme Q10 deficiency. Archives of neurology 20050201
An increase of oxidized coenzyme Q-10 occurs in the plasma of sporadic ALS patients. Journal of the neurological sciences 20050115
A novel therapeutic strategy for Ehlers-Danlos syndrome based on nutritional supplements. Medical hypotheses 20050101
Coenzyme Q10 therapy before cardiac surgery improves mitochondrial function and in vitro contractility of myocardial tissue. The Journal of thoracic and cardiovascular surgery 20050101
Changes in antioxidant status of myocardium during oxidative stress under the influence of coenzyme Q10. Biochemistry. Biokhimiia 20050101
Acute administration of red yeast rice (Monascus purpureus) depletes tissue coenzyme Q(10) levels in ICR mice. The British journal of nutrition 20050101
HMG-CoA reductase inhibitors and coenzyme Q10. Cardiology in review 20050101
Integrated treatment approach improves cognitive function in demented and clinically depressed patients. American journal of Alzheimer's disease and other dementias 20050101
Fellomyces mexicanus sp. nov., a new member of the yeast genus Fellomyces isolated from lichen Cryptothecia rubrocincta collected in Mexico. Microbiological research 20050101
Ask the doctors. I had a heart attack two years ago. Since then, I have been taking a statin, and my cholesterol numbers are excellent. My chiropractor suggests I should be taking CoQ10 along with my statin for even better cholesterol health. Does that make sense? Heart advisor 20050101
Effects of antioxidants coenzyme Q10 and lipoic acid on interleukin-1 beta-mediated inhibition of glucose-stimulated insulin release from cultured mouse pancreatic islets. Immunopharmacology and immunotoxicology 20050101
Treatment of massive hypertriglyceridemia resistant to PUFA and fibrates: a possible role for the coenzyme Q10? BioFactors (Oxford, England) 20050101
Prevention of coronary atherosclerosis by the use of combination therapy with antioxidant coenzyme Q10 and statins. Georgian medical news 20050101
Neuroprotective therapy in Parkinson's disease and motor complications: a search for a pathogenesis-targeted, disease-modifying strategy. Movement disorders : official journal of the Movement Disorder Society 20050101
Effect of oxidative stress on translocation of DAF-16 in oxygen-sensitive mutants, mev-1 and gas-1 of Caenorhabditis elegans. Mechanisms of ageing and development 20050101
[Coenzyme Q10: its biosynthesis and biological significance in animal organisms and in humans]. Postepy higieny i medycyny doswiadczalnej (Online) 20050101
Reduction of serum ubiquinol-10 and ubiquinone-10 levels by atorvastatin in hypercholesterolemic patients. Journal of atherosclerosis and thrombosis 20050101
Improvement of visual functions and fundus alterations in early age-related macular degeneration treated with a combination of acetyl-L-carnitine, n-3 fatty acids, and coenzyme Q10. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20050101
The effect of HMG-CoA reductase inhibitors on coenzyme Q10: possible biochemical/clinical implications. Drug safety 20050101
Enhanced anti-oxidant protection of liver membranes in long-lived rats fed on a coenzyme Q10-supplemented diet. Experimental gerontology 20050101
Quantitative determination of coenyzme Q10 by liquid chromatography and liquid chromatography/mass spectrometry in dairy products. Journal of AOAC International 20050101
Peroxynitrite in the pathogenesis of Parkinson's disease and the neuroprotective role of metallothioneins. Methods in enzymology 20050101
Coenzyme Q and the regulation of intracellular steady-state levels of superoxide in HL-60 cells. BioFactors (Oxford, England) 20050101
Effects of menopause and hormone replacement therapy on serum levels of coenzyme Q10 and other lipid-soluble antioxidants. BioFactors (Oxford, England) 20050101
Coenzyme Q10 in maternal plasma and milk throughout early lactation. BioFactors (Oxford, England) 20050101
Life-long supplementation with a low dosage of coenzyme Q10 in the rat: effects on antioxidant status and DNA damage. BioFactors (Oxford, England) 20050101
Coenzyme Q10 protects SHSY5Y neuronal cells from beta amyloid toxicity and oxygen-glucose deprivation by inhibiting the opening of the mitochondrial permeability transition pore. BioFactors (Oxford, England) 20050101
Muscle coenzyme Q10 concentrations in patients with probable and definite diagnosis of respiratory chain disorders. BioFactors (Oxford, England) 20050101
Coenzyme Q10 improves contractility of dysfunctional myocardium in chronic heart failure. BioFactors (Oxford, England) 20050101
An update of Coenzyme Q10 implications in male infertility: biochemical and therapeutic aspects. BioFactors (Oxford, England) 20050101
Stimulation of skin's energy metabolism provides multiple benefits for mature human skin. BioFactors (Oxford, England) 20050101
Coenzyme Q10 evaluation in pituitary-adrenal axis disease: preliminary data. BioFactors (Oxford, England) 20050101
Relationships between plasma CoQ10 levels and thyroid hormones in chronic obstructive pulmonary disease. BioFactors (Oxford, England) 20050101
Effect on absorption and oxidative stress of different oral Coenzyme Q10 dosages and intake strategy in healthy men. BioFactors (Oxford, England) 20050101
Effect of coenzyme Q10 as an antioxidant in beta-thalassemia/Hb E patients. BioFactors (Oxford, England) 20050101
Coenzyme Q10 supplementation reduces corticosteroids dosage in patients with bronchial asthma. BioFactors (Oxford, England) 20050101
Antioxidants and total oxyradical scavenging capacity during grass shrimp, Palaemonetes pugio, embryogenesis. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20041201
Alterations of erythrocyte free radical defense system, heart tissue lipid peroxidation, and lipid concentration in streptozotocin-induced diabetic rats under coenzyme Q10 supplementation. Saudi medical journal 20041201
Effects of dietary L-carnitine and coenzyme Q10 supplementation on performance and ascites mortality of broilers. Archives of animal nutrition 20041201
Response surface methodology for optimization and characterization of limonene-based coenzyme Q10 self-nanoemulsified capsule dosage form. AAPS PharmSciTech 20041201
[Protective roles of vitamin E and coenzyme Q10 in the inner ear mitochondrial DNA 4834 bp deletion mutation of rats]. Zhonghua er bi yan hou ke za zhi 20041201
Effect of atorvastatin on left ventricular diastolic function and ability of coenzyme Q10 to reverse that dysfunction. The American journal of cardiology 20041115
[Differential therapy of advanced Parkinson's disease with special reference to complementary therapeutic approaches]. Praxis 20041103
Comparison of coenzyme Q10 plasma levels in obese and normal weight children. Clinica chimica acta; international journal of clinical chemistry 20041101
Preconditioning by isoflurane is mediated by reactive oxygen species generated from mitochondrial electron transport chain complex III. Anesthesia and analgesia 20041101
Sphingomonas oligophenolica sp. nov., a halo- and organo-sensitive oligotrophic bacterium from paddy soil that degrades phenolic acids at low concentrations. International journal of systematic and evolutionary microbiology 20041101
Effects of an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a reductase on serum lipoproteins and ubiquinone-10 levels in patients with familial hypercholesterolemia. 1981. Atherosclerosis. Supplements 20041001
Preventive migraine therapy: what is new. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20041001
[Influence of homeopathically processed coenzyme q10 on proliferation and redifferentiation of endothelial cells]. Forschende Komplementarmedizin und klassische Naturheilkunde = Research in complementary and natural classical medicine 20041001
Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species. The Journal of neuroscience : the official journal of the Society for Neuroscience 20040908
Effect of melatonin cotreatment against kainic acid on coenzyme Q10, lipid peroxidation and Trx mRNA in rat hippocampus. The International journal of neuroscience 20040901
Rhodovarius lipocyclicus gen. nov. sp. nov., a new genus of the alpha-1 subclass of the Proteobacteria. Systematic and applied microbiology 20040901
Two new ballistoconidium-forming yeast species, Bullera melastomae and Bullera formosana, found in Taiwan. Systematic and applied microbiology 20040901
Pilot trial of high dosages of coenzyme Q10 in patients with Parkinson's disease. Experimental neurology 20040801
The analysis of the zero-order and the second derivative spectra of retinol acetate, tocopherol acetate and coenzyme Q10 and estimation of their analytical usefulness for their simultaneous determination in synthetic mixtures and pharmaceuticals. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040801
Coenzyme Q10 and diabetic endotheliopathy: oxidative stress and the 'recoupling hypothesis'. QJM : monthly journal of the Association of Physicians 20040801
Coenzyme Q10 concentrations in coronary artery disease. Clinical biochemistry 20040801
Analysis of coenzyme Q(10) in human plasma by column-switching liquid chromatography. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040615
Coenzyme Q10 changes are associated with metabolic syndrome. Clinica chimica acta; international journal of clinical chemistry 20040601
Effects of dichloroacetate and ubiquinone infusions on glycolysis activity and thermal sensitivity during sepsis. The Journal of laboratory and clinical medicine 20040601
Atorvastatin decreases the coenzyme Q10 level in the blood of patients at risk for cardiovascular disease and stroke. Archives of neurology 20040601
Oxidative stress to dopaminergic neurons as models of Parkinson's disease. Annals of the New York Academy of Sciences 20040601
Response of the senescent heart to stress: clinical therapeutic strategies and quest for mitochondrial predictors of biological age. Annals of the New York Academy of Sciences 20040601
1-Benzyl-1,2,3,4-tetrahydroisoquinoline, a Parkinsonism-inducing endogenous toxin, increases alpha-synuclein expression and causes nuclear damage in human dopaminergic cells. Journal of neuroscience research 20040515
Effect of coenzyme Q10 on the mitochondrial function of skin fibroblasts from Parkinson patients. Journal of the neurological sciences 20040515
Environmental, pharmacological, and genetic modulation of the HD phenotype in transgenic mice. Experimental neurology 20040501
The natural treatment of hypertension. Journal of clinical hypertension (Greenwich, Conn.) 20040501
The impact of alpha-lipoic acid, coenzyme Q10 and caloric restriction on life span and gene expression patterns in mice. Free radical biology & medicine 20040415
Evaluation of cytotoxicity of oils used in coenzyme Q10 Self-emulsifying Drug Delivery Systems (SEDDS). International journal of pharmaceutics 20040401
Cofactor treatment improves ATP synthetic capacity in patients with oxidative phosphorylation disorders. Molecular genetics and metabolism 20040401
Questions & answers. I take a statin to lower my LDL (bad) cholesterol level, but I've heard statins inhibit the production of coenzyme Q10 (CoQ10). Should I take a CoQ10 supplement? Health news (Waltham, Mass.) 20040401
Cerebrospinal fluid concentrations of idebenone in Friedreich ataxia patients. Neuropediatrics 20040401
Measurement of reduced and oxidized coenzyme Q9 and coenzyme Q10 levels in mouse tissues by HPLC with coulometric detection. Clinica chimica acta; international journal of clinical chemistry 20040301
A longitudinal study of antioxidant status in phenylketonuric patients. Clinical biochemistry 20040301
High glucose levels induce an increase in membrane antioxidants, in terms of vitamin E and coenzyme Q10, in children and adolescents with type 1 diabetes. Diabetes care 20040201
Effect of simvastatin on remodeling of the left ventricle and aorta in L-NAME-induced hypertension. Life sciences 20040123
Neuroprotection in Parkinson disease: mysteries, myths, and misconceptions. JAMA 20040121
Antioxidants effectively prevent oxidation-induced protein damage in OLN 93 cells. Archives of biochemistry and biophysics 20040101
Evaluation of cytogenetic and DNA damage in mitochondrial disease patients: effects of coenzyme Q10 therapy. Mutagenesis 20040101
Vitamins, supplements, herbal medicines, and arrhythmias. Cardiology in review 20040101
Lipid-soluble antioxidants and pregnancy: maternal serum levels of coenzyme Q10, alpha-tocopherol and gamma-tocopherol in preeclampsia and normal pregnancy. Gynecologic and obstetric investigation 20040101
Simultaneous determination of coenzyme Q10, cholesterol, and major cholesterylesters in human blood plasma. Methods in enzymology 20040101
Role of magnesium, coenzyme Q10, riboflavin, and vitamin B12 in migraine prophylaxis. Vitamins and hormones 20040101
Coenzyme Q10 inhibits mitochondrial complex-1 down-regulation and nuclear factor-kappa B activation. Journal of cellular and molecular medicine 20040101
Coenzyme Q 10 improves lactic acidosis, strokelike episodes, and epilepsy in a patient with MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes). Clinical neuropharmacology 20040101
Oxidative stress and coenzyme Q10 supplementation in renal transplant recipients. International urology and nephrology 20040101
Phase 1 study of multiple biomarkers for metabolism and oxidative stress after one-week intake of broccoli sprouts. BioFactors (Oxford, England) 20040101
The effect of coenzyme Q10 and vitamin E on the regeneration of skeletal muscles in pigs. Polish journal of veterinary sciences 20040101
Plasma levels and redox status of coenzyme Q10 in infants and children. BioFactors (Oxford, England) 20040101
Nutrition and herbs. Cholesterol drug side effects may be linked to low nutrient levels. TreatmentUpdate 20040101
Novel homoplasmic mutation in the mitochondrial tRNATyr gene associated with atypical mitochondrial cytopathy presenting with focal segmental glomerulosclerosis. American journal of medical genetics. Part A 20031201
Sporobolomyces magnisporus sp. nov., a new yeast species in the Erythrobasidium cluster isolated from plants in Taiwan. The Journal of general and applied microbiology 20031201
The ubiquinone-binding site of the Saccharomyces cerevisiae succinate-ubiquinone oxidoreductase is a source of superoxide. The Journal of biological chemistry 20031128
Only transient increase of serum CoQ subset 10 during long-term CoQ10 therapy in mitochondrial ophthalmoplegia. European journal of medical research 20031112
Anti-oxidant effects of coenzyme Q10 on experimental viral myocarditis in mice. Journal of cardiovascular pharmacology 20031101
Targeting cellular energy production in neurological disorders. Expert opinion on investigational drugs 20031001
Effect of the supplemental use of antioxidants vitamin C, vitamin E, and coenzyme Q10 for the prevention and treatment of cancer. Evidence report/technology assessment (Summary) 20031001
Plasma concentrations of coenzyme Q10 and tocopherols in cervical intraepithelial neoplasia and cervical cancer. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20030801
Coenzyme Q(10) supplementation inhibits aortic lipid oxidation but fails to attenuate intimal thickening in balloon-injured New Zealand white rabbits. Free radical biology & medicine 20030801
Evidence for increased oxidative stress in peroxisomal D-bifunctional protein deficiency. Molecular genetics and metabolism 20030801
Cell surface NADH oxidases (ECTO-NOX proteins) with roles in cancer, cellular time-keeping, growth, aging and neurodegenerative diseases. Free radical research 20030801
Coenzyme q10 prevents apoptosis by inhibiting mitochondrial depolarization independently of its free radical scavenging property. The Journal of biological chemistry 20030725
Reconstitution of recombinant uncoupling proteins: UCP1, -2, and -3 have similar affinities for ATP and are unaffected by coenzyme Q10. The Journal of biological chemistry 20030711
Antioxidants decreases the intensification of low density lipoprotein in vivo peroxidation during therapy with statins. Molecular and cellular biochemistry 20030701
Molecular mechanisms of glutamate neurotoxicity in mixed cultures of NT2-derived neurons and astrocytes: protective effects of coenzyme Q10. Journal of neuroscience research 20030615
Activating omega-6 polyunsaturated fatty acids and inhibitory purine nucleotides are high affinity ligands for novel mitochondrial uncoupling proteins UCP2 and UCP3. The Journal of biological chemistry 20030606
Coenzyme Q10 levels in Prader-Willi syndrome: comparison with obese and non-obese subjects. American journal of medical genetics. Part A 20030601
Mitochondria, oxidative damage, and inflammation in Parkinson's disease. Annals of the New York Academy of Sciences 20030601
Insulin-like growth factor I (IGF-1) supplementation prevents diabetes-induced alterations in coenzymes Q9 and Q10. Acta diabetologica 20030601
Metallothionein attenuates 3-morpholinosydnonimine (SIN-1)-induced oxidative stress in dopaminergic neurons. Antioxidants & redox signaling 20030601
Effect of supplemental antioxidants vitamin C, vitamin E, and coenzyme Q10 for the prevention and treatment of cardiovascular disease. Evidence report/technology assessment (Summary) 20030601
Asymmetric binding of the high-affinity Q(H)(*)(-) ubisemiquinone in quinol oxidase (bo3) from Escherichia coli studied by multifrequency electron paramagnetic resonance spectroscopy. Biochemistry 20030520
Immunomodulatory effects of L-carnitine and q10 in mouse spleen exposed to low-frequency high-intensity magnetic field. Toxicology 20030503
Combined effect of coenzyme Q10 and fenofibrate on forearm microcirculatory function in type 2 diabetes. Atherosclerosis 20030501
Neuroprotective effects of coenzyme Q10 at rostral ventrolateral medulla against fatality during experimental endotoxemia in the rat. Shock (Augusta, Ga.) 20030501
Ubiquinone: cholesterol's reclusive cousin. Annals of clinical biochemistry 20030501
Plasma ubiquinone status and response to six-month supplementation combined with multivitamins in healthy elderly women--results of a randomized, double-blind, placebo-controlled study. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20030501
[Effect of Coenzyme Q10 and Ginkgo biloba on warfarin dosage in patients on long-term warfarin treatment. A randomized, double-blind, placebo-controlled cross-over trial]. Ugeskrift for laeger 20030428
Cerebellar ataxia and coenzyme Q10 deficiency. Neurology 20030408
Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Molecular and cellular biochemistry 20030401
Distribution and breakdown of labeled coenzyme Q10 in rat. Free radical biology & medicine 20030301
[Effects of nutrient conditions and fed-batch culture on CoQ10 production by Rhizobium radiobacter WSH2601]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20030301
[Rhabdomyolysis following cerivastatin monotherapy--implications for therapy with HMG-CoA reductase inhibitors]. Der Nervenarzt 20030201
Candida albicans and selenium. Medical hypotheses 20030201
The mammalian cytosolic selenoenzyme thioredoxin reductase reduces ubiquinone. A novel mechanism for defense against oxidative stress. The Journal of biological chemistry 20030124
Total coenzyme Q10 concentrations in Asian men following multiple oral 50-mg doses administered as coenzyme Q10 sustained release tablets or regular tablets. Biological & pharmaceutical bulletin 20030101
Relative bioavailability and antioxidant potential of two coenzyme q10 preparations. Annals of nutrition & metabolism 20030101
Bioenergetic approaches for neuroprotection in Parkinson's disease. Annals of neurology 20030101
Effect of taurine and coenzyme Q10 in patients with acute myocardial infarction. Advances in experimental medicine and biology 20030101
Mitotropic compounds for the treatment of age-related macular degeneration. The metabolic approach and a pilot study. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20030101
The response of bile secretion and ubiquinone Q10 to hyperglycaemia in sheep. Polish journal of veterinary sciences 20030101
Review: Mitochondrial medicine--cardiomyopathy caused by defective oxidative phosphorylation. Annals of clinical and laboratory science 20030101
Complementary or alternative medicine and cardiovascular health. The Case manager 20030101
Reversal of statin toxicity to human lymphocytes in tissue culture. Drug metabolism and drug interactions 20030101
Effect of UV-C mediated oxidative stress in leukemia cell lines and its relation to ubiquinone content. BioFactors (Oxford, England) 20030101
The clinical use of HMG CoA-reductase inhibitors and the associated depletion of coenzyme Q10. A review of animal and human publications. BioFactors (Oxford, England) 20030101
Statins lower plasma and lymphocyte ubiquinol/ubiquinone without affecting other antioxidants and PUFA. BioFactors (Oxford, England) 20030101
Statin cardiomyopathy? A potential role for Co-Enzyme Q10 therapy for statin-induced changes in diastolic LV performance: description of a clinical protocol. BioFactors (Oxford, England) 20030101
Friedreich's Ataxia: disease mechanisms, antioxidant and Coenzyme Q10 therapy. BioFactors (Oxford, England) 20030101
Derivatised alpha-tocopherol as a CoQ10 carrier in a novel water-soluble formulation. BioFactors (Oxford, England) 20030101
Coenzyme Q10-containing composition (Immugen) protects against occupational and environmental stress in workers of the gas and oil industry. BioFactors (Oxford, England) 20030101
The effect of Cyclosporine A chronic administration on the antioxidant pattern of rat liver mitochondria: structural and functional consequences. BioFactors (Oxford, England) 20030101
The combined use of oral and topical lipophilic antioxidants increases their levels both in sebum and stratum corneum. BioFactors (Oxford, England) 20030101
Coenzyme Q10, antioxidant status and ApoE isoforms. BioFactors (Oxford, England) 20030101
Coenzyme Q10 in plasma and erythrocytes: comparison of antioxidant levels in healthy probands after oral supplementation and in patients suffering from sickle cell anemia. Clinica chimica acta; international journal of clinical chemistry 20021201
A close look at coenzyme Q10 and policosanol. Do these supplements live up to their claims for improving heart health? Harvard heart letter : from Harvard Medical School 20021201
Blood mononuclear cell coenzyme Q10 concentration and mitochondrial respiratory chain succinate cytochrome-c reductase activity in phenylketonuric patients. Journal of inherited metabolic disease 20021201
A cellular model for Friedreich Ataxia reveals small-molecule glutathione peroxidase mimetics as novel treatment strategy. Human molecular genetics 20021115
Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. European journal of clinical nutrition 20021101
Effect of ischemia-reperfusion on heart mitochondria from hyperthyroid rats. Cardiovascular research 20021001
Testicular toxicity effects of magnetic field exposure and prophylactic role of coenzyme Q10 and L-carnitine in mice. Pharmacological research 20021001
Protection of cultured oligodendrocytes against tumor necrosis factor-alpha by the antioxidants coenzyme Q(10) and N-acetyl cysteine. Brain research bulletin 20020930
Decreased levels of coenzyme Q(10) in patients with bronchial asthma. Allergy 20020901
Serum levels of coenzyme Q in patients with Lewy body disease. Journal of neural transmission (Vienna, Austria : 1996) 20020901
Identification of the residues involved in stabilization of the semiquinone radical in the high-affinity ubiquinone binding site in cytochrome bo(3) from Escherichia coli by site-directed mutagenesis and EPR spectroscopy. Biochemistry 20020827
beta2-Integrin and lipid modifications indicate a non-antioxidant mechanism for the anti-atherogenic effect of dietary coenzyme Q10. Biochemical and biophysical research communications 20020816
Diabetes and the role of isoprenoid biosynthesis. FEBS letters 20020814
Comparison of the effects of alpha-tocopherol, ubiquinone-10 and probucol at therapeutic doses on atherosclerosis in WHHL rabbits. Atherosclerosis 20020801
The NADH oxidase activity of the plasma membrane of synaptosomes is a major source of superoxide anion and is inhibited by peroxynitrite. Journal of neurochemistry 20020801
Plasma antioxidants in pediatric patients with glycogen storage disease, diabetes mellitus, and hypercholesterolemia. Free radical biology & medicine 20020701
Curcuma longa extract supplementation reduces oxidative stress and attenuates aortic fatty streak development in rabbits. Arteriosclerosis, thrombosis, and vascular biology 20020701
Intensification of free radical oxidation of low-density lipoproteins in the plasma of patients with ischemic heart disease receiving beta-hydroxy-beta-methylglutaryl-coenzyme A reductase inhibitor cerivastatin and inhibition of low-density lipoprotein peroxidation with antioxidant probucol. Bulletin of experimental biology and medicine 20020701
Optimization of a self-nanoemulsified tablet dosage form of Ubiquinone using response surface methodology: effect of formulation ingredients. International journal of pharmaceutics 20020620
Assay of coenzyme Q(10) in plasma by a single dilution step. Analytical biochemistry 20020601
Enhancement of muscular performance by a coformulation of propionyl-L-carnitine, coenzyme Q10, nicotinamide, riboflavin and pantothenic acid in the rat. Physiology & behavior 20020601
Nutritional supplementation with MyoVive repletes essential cardiac myocyte nutrients and reduces left ventricular size in patients with left ventricular dysfunction. American heart journal 20020601
Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thrombosis and haemostasis 20020601
EPR characterization of ubisemiquinones and iron-sulfur cluster N2, central components of the energy coupling in the NADH-ubiquinone oxidoreductase (complex I) in situ. Journal of bioenergetics and biomembranes 20020601
Effect of MPTP on Dopamine metabolism in Ames dwarf mice. Neurochemical research 20020601
Lovastatin induces cell death in cardiomyocytes that is not reversible by coenzyme Q 10. Pharmacology & toxicology 20020601
Anticoagulant effects on plasma coenzyme Q(10) estimated by HPLC with coulometric detection. Clinica chimica acta; international journal of clinical chemistry 20020401
Modulation of apoptosis and improved redox metabolism with the use of a new antioxidant formula. Biochemical pharmacology 20020401
Human aging and global function of coenzyme Q10. Annals of the New York Academy of Sciences 20020401
Mitochondrial factors in the pathogenesis of diabetes: a hypothesis for treatment. Alternative medicine review : a journal of clinical therapeutic 20020401
[Mitochondrial dysfunction in migraine]. Nihon rinsho. Japanese journal of clinical medicine 20020401
[Ophthalmoplegia]. Nihon rinsho. Japanese journal of clinical medicine 20020401
[Drug therapy for mitochondrial diseases]. Nihon rinsho. Japanese journal of clinical medicine 20020401
Ceramide-dependent caspase 3 activation is prevented by coenzyme Q from plasma membrane in serum-deprived cells. Free radical research 20020401
Coenzyme Q10 depletion is comparatively less detrimental to human cultured skin fibroblasts than respiratory chain complex deficiencies. Free radical research 20020401
Coenzyme Q10: absorption, antioxidative properties, determinants, and plasma levels. Free radical research 20020401
Reduction of 1,4-quinone and ubiquinones by hydrogen atom transfer under UVA irradiation. Free radical research 20020401
Ubiquinol and a coenzyme Q reducing system protect platelet mitochondrial function of transfusional buffy coats from oxidative stress. Free radical research 20020401
Coenzyme Q10 as a possible treatment for neurodegenerative diseases. Free radical research 20020401
Lipophilic antioxidants in human sebum and aging. Free radical research 20020401
Coenzyme Q(10) improves endothelial dysfunction of the brachial artery in Type II diabetes mellitus. Diabetologia 20020301
Use of alternative pharmacotherapy in management of cardiovascular diseases. The American journal of managed care 20020301
Effect of coenzyme Q10 supplementation on mitochondrial function after myocardial ischemia reperfusion. The Journal of surgical research 20020201
Lipid-lowering drugs (statins), cholesterol, and coenzyme Q10. The Baycol case--a modern Pandora's box. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20020201
Ubiquinone-10 content in lymphocytes of phenylketonuric patients. Clinical biochemistry 20020201
The placebo effect and randomized trials: analysis of alternative medicine. The Urologic clinics of North America 20020201
Coenzyme Q10 and differences in coronary heart disease risk in Asian Indians and Chinese. Free radical biology & medicine 20020115
How to re-energise old mitochondria without shooting yourself in the foot. Biogerontology 20020101
Effects of combined quercetin and coenzyme Q(10) treatment on oxidative stress in normal and diabetic rats. Journal of biochemical and molecular toxicology 20020101
Coenzyme Q(10) and idebenone in the therapy of respiratory chain diseases: rationale and comparative benefits. Molecular genetics and metabolism 20020101
Antioxidative properties of coenzyme Q10 and vitamin E in exposure to xylene and gasoline and their mixture with methanol. Acta poloniae pharmaceutica 20020101
Biochemical functions of coenzyme Q10. Journal of the American College of Nutrition 20011201
Therapeutic trial in the first three Asian cases of ethylmalonic encephalopathy: response to riboflavin. Journal of inherited metabolic disease 20011201
Anti-aging products, Part I. Can supplements rewind our body clocks? Harvard women's health watch 20011101
Oxidative stress in the neonate. Early human development 20011101
Coenzyme Q10, exercise lactate and CTG trinucleotide expansion in myotonic dystrophy. Brain research bulletin 20011001
The site of production of superoxide radical in mitochondrial Complex I is not a bound ubisemiquinone but presumably iron-sulfur cluster N2. FEBS letters 20010921
Enhanced mitochondrial testicular antioxidant capacity in Goto-Kakizaki diabetic rats: role of coenzyme Q. American journal of physiology. Cell physiology 20010901
Nanoparticles of a polyelectrolyte-fatty acid complex: carriers for Q10 and triiodothyronine. Journal of controlled release : official journal of the Controlled Release Society 20010810
The effect of pravastatin and atorvastatin on coenzyme Q10. American heart journal 20010801
Mitochondria as target for antiischemic drugs. Advanced drug delivery reviews 20010702
Oxidative stress and plasma concentrations of coenzyme Q10, alpha-tocopherol, and beta-carotene in patients with a mild to moderate decrease of kidney function. Nephron 20010701
Electrogenic proton transfer in Rhodobacter sphaeroides reaction centers: effect of coenzyme Q(10) substitution by decylubiquinone in the Q(B) binding site. FEBS letters 20010615
The origin of cluster N2 of the energy-transducing NADH-quinone oxidoreductase: comparisons of phylogenetically related enzymes. Journal of bioenergetics and biomembranes 20010601
[Effect of coenzyme Q10 in patients with kidney diseases]. Casopis lekaru ceskych 20010524
Analysis of ubidecarenone (CoQ10) aqueous samples using reversed phase liquid chromatography. Die Pharmazie 20010501
Sphingomonas pituitosa sp. nov., an exopolysaccharide-producing bacterium that secretes an unusual type of sphingan. International journal of systematic and evolutionary microbiology 20010501
Dietary cosupplementation with vitamin E and coenzyme Q(10) inhibits atherosclerosis in apolipoprotein E gene knockout mice. Arteriosclerosis, thrombosis, and vascular biology 20010401
Recombinant expression of N-terminal truncated mutants of the membrane bound mouse, rat and human flavoenzyme dihydroorotate dehydrogenase. A versatile tool to rate inhibitor effects? European journal of biochemistry 20010301
In vitro test for the effectiveness of antioxidants as inhibitors of thiyl radical-induced reactions with unsaturated fatty acids. Journal of agricultural and food chemistry 20010301
Quercetin, coenzyme Q10, and L-canavanine as protective agents against lipid peroxidation and nitric oxide generation in endotoxin-induced shock in rat brain. Pharmacological research 20010301
Incorporation of the model drug ubidecarenone into solid lipid nanoparticles. Pharmaceutical research 20010301
HPLC analysis of reduced and oxidized coenzyme Q(10) in human plasma. Clinical chemistry 20010201
Dual involvement of coenzyme Q10 in redox signaling and inhibition of death signaling in the rat heart mitochondria. Antioxidants & redox signaling 20010201
Lipophilic antioxidants and polyunsaturated fatty acids in lipoprotein classes: distribution and interaction. European journal of clinical nutrition 20010201
Does coenzyme Q10 play a role in opposing oxidative stress in patients with age-related macular degeneration? Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20010101
Effects of coenzyme Q10 treatment on antioxidant pathways in normal and streptozotocin-induced diabetic rats. Journal of biochemical and molecular toxicology 20010101
Oxidative stress and the role of antioxidants in cardiovascular risk reduction. Progress in cardiovascular nursing 20010101
The effect of coenzyme Q10 on blood ascorbic acid, vitamin E, an lipid peroxide in chronic cadmium intoxication. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20010101
Effect of ubidecarenone on warfarin anticoagulation and pharmacokinetics of warfarin enantiomers in rats. Drug metabolism and drug interactions 20010101
[Mitochondrial diseases with recurrent myoglobinuria]. Ryoikibetsu shokogun shirizu 20010101
The effect of captopril on nitric oxide formation and on generation of radical forms of mitochondrial respiratory chain compounds in ischemic rat heart. Physiological research 20010101
Neuronal death in the rat hippocampus in experimental diabetes and cerebral ischaemia treated with antioxidants. Folia neuropathologica 20010101
Effects of oral coenzyme Q10 supplementation on sodium nitrite-induced lipid peroxidation in rats. Roczniki Panstwowego Zakladu Higieny 20010101
Pneumocystis carinii f. sp. carinii synthesizes de novo four homologs of ubiquinone. The Journal of eukaryotic microbiology 20010101
Influence of peroxisome proliferator-activated receptor alpha on ubiquinone biosynthesis. Journal of molecular biology 20000331
Coenzyme Q10 does not prevent oral dyskinesias induced by long-term haloperidol treatment of rats. Pharmacology, biochemistry, and behavior 19991101
Species-related inhibition of human and rat dihydroorotate dehydrogenase by immunosuppressive isoxazol and cinchoninic acid derivatives. Biochemical pharmacology 19981101
The universality of bioenergetic disease and amelioration with redox therapy. Biochimica et biophysica acta 19950524
Biochemical, physiological and medical aspects of ubiquinone function. Biochimica et biophysica acta 19950524
Aminooxyacetic acid striatal lesions attenuated by 1,3-butanediol and coenzyme Q10. Neuroscience letters 19940815
Protective effect of coenzyme Q10 on anthracyclines cardiotoxicity: control study in children with acute lymphoblastic leukemia and non-Hodgkin lymphoma. Molecular aspects of medicine 19940101
Cytochrome c reductase purified from Crithidia fasciculata contains an atypical cytochrome c1. The Journal of biological chemistry 19921005
Dietary supplementation with coenzyme Q10 results in increased levels of ubiquinol-10 within circulating lipoproteins and increased resistance of human low-density lipoprotein to the initiation of lipid peroxidation. Biochimica et biophysica acta 19920626
[Vitamin E, ubiquinone and ubiquinone-dependent enzymes in experimental myocarditis]. Ukrainskii biokhimicheskii zhurnal (1978) 19910101
Lovastatin, isoprenes, and myopathy. Lancet (London, England) 19891104
Research on coenzyme Q10 in clinical medicine and in immunomodulation. Drugs under experimental and clinical research 19850101
Mechanism of acute anthracycline cardiotoxicity in isolated rat hearts: carminomycin versus daunomycin. Cancer research 19840401
Mechanism of chlorpromazine-induced arrhythmia -- arrhythmia and mitochondrial dysfunction. Journal of electrocardiology 19810701
Adriamycin cardiotoxicity: early detection by systolic time interval and possible prevention by coenzyme Q10. Cancer treatment reports 19780601

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