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298-96-4

298-96-4 | 2,3,5-Triphenyltetrazolium chloride

CAS No: 298-96-4 Catalog No: AG00383L MDL No:MFCD00011963

Product Description

Catalog Number:
AG00383L
Chemical Name:
2,3,5-Triphenyltetrazolium chloride
CAS Number:
298-96-4
Molecular Formula:
C19H15ClN4
Molecular Weight:
334.8022
MDL Number:
MFCD00011963
IUPAC Name:
2,3,5-triphenyltetrazol-2-ium;chloride
InChI:
InChI=1S/C19H15N4.ClH/c1-4-10-16(11-5-1)19-20-22(17-12-6-2-7-13-17)23(21-19)18-14-8-3-9-15-18;/h1-15H;1H/q+1;/p-1
InChI Key:
PKDBCJSWQUOKDO-UHFFFAOYSA-M
SMILES:
c1ccc(cc1)c1nn([n+](n1)c1ccccc1)c1ccccc1.[Cl-]
EC Number:
206-071-6
UNII:
D25727K0RB
NSC Number:
5053

Properties

Complexity:
330  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
334.099g/mol
Formal Charge:
0
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
334.807g/mol
Monoisotopic Mass:
334.099g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
34.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0

Literature

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A therapeutic window for intravenous administration of autologous bone marrow after cerebral ischemia in adult rats. Brain research 20040508
Wide therapeutic time window for nimesulide neuroprotection in a model of transient focal cerebral ischemia in the rat. Brain research 20040508
Reduction of 'no-reflow' phenomenon by intra-aortic balloon counterpulsation in a randomized magnetic resonance imaging experimental study. Journal of the American College of Cardiology 20040407
An optimized triphenyltetrazolium chloride method for identification of cerebral infarcts. Brain research. Brain research protocols 20040401
Validation of a simple and inexpensive method for the quantitation of infarct in the rat brain. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20040401
Osmotic induced stimulation of the reduction of the viability dye 2,3,5-triphenyltetrazolium chloride by maize roots and callus cultures. Journal of plant physiology 20040401
Extension of ischemic therapeutic time window by a free radical scavenger, Edaravone, reperfused with tPA in rat brain. Neurological research 20040401
FK506 reduces infarct volume due to permanent focal cerebral ischemia by maintaining BAD turnover and inhibiting cytochrome c release. Brain research 20040319
The effects of citicoline and lamotrigine alone and in combination following permanent middle cerebral artery occlusion in rats. The International journal of neuroscience 20040201
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Involvement of nitric oxide and prostaglandin pathways in the cardioprotective actions of bradykinin in rats with experimental myocardial infarction. Pharmacological research 20040101
Antithrombin reduces the ischemia/reperfusion-induced spinal cord injury in rats by attenuating inflammatory responses. Thrombosis and haemostasis 20040101
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Neurotransmitter release in experimental stroke models: the role of glutamate-GABA interaction. Advances in experimental medicine and biology 20040101
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[A plate method to screen for microorganisms producing xylose isomerase]. Mikrobiologiia 20040101
Isolating Mortierella alpina strains of high yield of arachidonic acid. Letters in applied microbiology 20040101
Anandamide content is increased and CB1 cannabinoid receptor blockade is protective during transient, focal cerebral ischemia. Neuroscience 20040101
17beta-Estradiol extends ischemic thresholds and exerts neuroprotective effects in cerebral subcortex against transient focal cerebral ischemia in rats. Brain research 20031212
The neuronal nitric oxide synthase inhibitor, TRIM, as a neuroprotective agent: effects in models of cerebral ischaemia using histological and magnetic resonance imaging techniques. Brain research 20031212
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[An improved quantitative method for evaluation of ischemic injury and neuroprotection in mouse brain slices]. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20031201
Evaluation of stunned and infarcted canine myocardium by real time myocardial contrast echocardiography. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20031101
Administration of the p38 MAPK inhibitor SB203580 affords brain protection with a wide therapeutic window against focal ischemic insult. Journal of neuroscience research 20030815
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Post-treatment with a novel PARG inhibitor reduces infarct in cerebral ischemia in the rat. Brain research 20030718
Inhibition of apoptosis by hyperbaric oxygen in a rat focal cerebral ischemic model. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20030701
Efficiency of a pneumococcal opsonophagocytic killing assay improved by multiplexing and by coloring colonies. Clinical and diagnostic laboratory immunology 20030701
Vitality of tree fine roots: reevaluation of the tetrazolium test. Tree physiology 20030301
Sensitivity and specificity of the Sanita-kun Aerobic Count: internal validation and independent laboratory study. Journal of AOAC International 20030101
Culture treatments for enhancing post-thaw recovery of cryopreserved suspension cells of potato cv. Desiree. Cellular & molecular biology letters 20030101
Melatonin reduces cerebral edema formation caused by transient forebrain ischemia in rats. Life sciences 20021220
Restricted clinical efficacy of cyclosporin A on rat transient middle cerebral artery occlusion. Life sciences 20021220
Adenovirus-mediated Bcl-X(L) expression using a neuron-specific synapsin-1 promoter protects against disseminated neuronal injury and brain infarction following focal cerebral ischemia in mice. Neurobiology of disease 20021101
Effect of 3-[1-(phenylmethyl)-4-piperidinyl]-1-(2,3,4,5-tetrahydro-1H-1-benzazepin-8-yl)-1-propanone fumarate, a novel acetylcholinesterase inhibitor, on spatial cognitive impairment induced by chronic cerebral hypoperfusion in rats. Neuroscience letters 20021004
Blood brain barrier in right- and left-pawed female rats assessed by a new staining method. The International journal of neuroscience 20020901
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Quantitative analysis of acute myocardial infarct in rat hearts with ischemia-reperfusion using a high-resolution stationary SPECT system. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20020701
Validation of image analysis for enzyme histochemical and immunocytochemical staining. Biotechnic & histochemistry : official publication of the Biological Stain Commission 20020701
Spontaneous ischemic events in the brain and heart adapt the hearts of severely atherosclerotic mice to ischemia. Arteriosclerosis, thrombosis, and vascular biology 20020601
Distribution of brain oedema in the contralateral hemisphere after cerebral infarction: repeated MRI measurement in the rat. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20020501
Models of cardiac ischemia-reperfusion injury in dogs and rats. Current protocols in pharmacology 20020501
Imaging of myocardial infarction: comparison of magnevist and gadophrin-3 in rabbits. Journal of the American College of Cardiology 20020417
Identification of Candida dubliniensis among oral yeast isolates from an Italian population of human immunodeficiency virus-infected (HIV+) subjects. Oral microbiology and immunology 20020401
Temporal changes in reversible cerebral ischemia on perfusion- and diffusion-weighted magnetic resonance imaging: the value of relative cerebral blood volume maps. Neuroradiology 20020201
[Morphology and enzyme activity of nonculturable forms of Vibrio cholerae]. Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20020101
A new model of localized ischemia in rat somatosensory cortex produced by cortical compression. Stroke 20011101
Effects of recombinant tissue plasminogen activator after intraluminal thread occlusion in mice: role of hemodynamic alterations. Stroke 20011101
Development of a selective differential agar for isolation and enumeration of Campylobacter spp. Journal of food protection 20011101
Use of isogenic human cancer cells for high-throughput screening and drug discovery. Nature biotechnology 20011001
Systemic administration of a water-soluble hexasulfonated C(60) (FC(4)S) reduces cerebral ischemia-induced infarct volume in gerbils. Neuroscience letters 20010928
Comparative study of 2,3,5-triphenyltetrazolium chloride (TTC) and hematoxylin-eosin staining for quantification of early brain ischemic injury in cats. Neurological research 20010901
The sites of interaction of triphenyltetrazolium chloride with mitochondrial respiratory chains. FEMS microbiology letters 20010821
Evaluation of thermal therapy in a prostate cancer model using a wet electrode radiofrequency probe. Journal of endourology 20010801
Metabolism of 99mTc-ethylcysteinate dimer in infarcted brain tissue of rats. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20010501
Differential effect of preconditioning on post-ischaemic myocardial performance in the absence of substantial infarction and in extensively infarcted rat hearts. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20010401
A water-based triphenyltetrazolium chloride method for the evaluation of green plant tissue viability. Phytochemical analysis : PCA 20010101
Detection of myocardial viability in ischemic-reperfused rat hearts by Tc-99m sestamibi kinetics. Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 20010101
Delayed institution of hypertension during focal cerebral ischemia: effect on brain edema. Acta neuropathologica 19910101
Hypertension and hemodilution during cerebral ischemia reduce brain injury and edema. The American journal of physiology 19900701

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