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29108-89-2

29108-89-2 | 2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-[(2R,5R)-tetrahydro-5-methyl-2-furanyl]-

CAS No: 29108-89-2 Catalog No: AG002XCD MDL No:

Product Description

Catalog Number:
AG002XCD
Chemical Name:
2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-[(2R,5R)-tetrahydro-5-methyl-2-furanyl]-
CAS Number:
29108-89-2
Molecular Formula:
C10H14N2O3
Molecular Weight:
210.2298
IUPAC Name:
5-methyl-1-[(2R,5R)-5-methyloxolan-2-yl]pyrimidine-2,4-dione
InChI:
InChI=1S/C10H14N2O3/c1-6-5-12(10(14)11-9(6)13)8-4-3-7(2)15-8/h5,7-8H,3-4H2,1-2H3,(H,11,13,14)/t7-,8-/m1/s1
InChI Key:
JIQLAAKADXSVTE-HTQZYQBOSA-N
SMILES:
Cc1cn([C@H]2CC[C@H](O2)C)c(=O)[nH]c1=O

Properties

Complexity:
338  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
0
Exact Mass:
210.1g/mol
Formal Charge:
0
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
210.233g/mol
Monoisotopic Mass:
210.1g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
58.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.6  

Literature

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Reverse transcription of the pFOXC mitochondrial retroplasmids of Fusarium oxysporum is protein primed. Mobile DNA 20110101
Chemical stability of new acyclovir analogues with peptidomimetics. Scientia pharmaceutica 20110101
A novel nucleotide kinase encoded by gene 1.7 of bacteriophage T7. Molecular microbiology 20100701
HIV-1 RT Inhibitors with a Novel Mechanism of Action: NNRTIs that Compete with the Nucleotide Substrate. Viruses 20100401
Quadruplex MAPH: improvement of throughput in high-resolution copy number screening. BMC genomics 20090101
A linchpin carbacyclization approach for the synthesis of carbanucleosides. The Journal of organic chemistry 20081205
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Thymidine analogs as potential antiviral agents. Nucleic acids symposium series (2004) 20080101
Two X family DNA polymerases, lambda and mu, in meiotic tissues of the basidiomycete, Coprinus cinereus. Chromosoma 20071201
The contribution of peroxynitrite generation in HIV replication in human primary macrophages. Retrovirology 20070101
The influence of natural substrates and inhibitors on the nucleotide-dependent excision activity of HIV-1 reverse transcriptase in the infected cell. Current pharmaceutical design 20060101
Synthesis and HIV-1 reverse transcriptase inhibitor activity of some 2,5,6-substituted benzoxazole, benzimidazole, benzothiazole and oxazolo(4,5-b)pyridine derivatives. Arzneimittel-Forschung 20030101
An exonucleolytic activity of human apurinic/apyrimidinic endonuclease on 3' mispaired DNA. Nature 20020207
Crystal structures of a ddATP-, ddTTP-, ddCTP, and ddGTP- trapped ternary complex of Klentaq1: insights into nucleotide incorporation and selectivity. Protein science : a publication of the Protein Society 20010601
Chronic in vitro exposure to 3'-azido-2', 3'-dideoxythymidine induces senescence and apoptosis and reduces tumorigenicity of metastatic mouse mammary tumor cells. Breast cancer research and treatment 20010101

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