200,000+ products from a single source!
sales@angenechem.com
Home > Other Building Blocks > 28957-04-2
28957-04-2 | Kaur-16-en-15-one, 7,20-epoxy-1,6,7,14-tetrahydroxy-, (1α,6β,7α,14R)-
CAS No: 28957-04-2 Catalog No: AG002UZH MDL No:MFCD00221762
Product Description
Catalog Number:
AG002UZH
Chemical Name:
Kaur-16-en-15-one, 7,20-epoxy-1,6,7,14-tetrahydroxy-, (1α,6β,7α,14R)-
CAS Number:
28957-04-2
Molecular Formula:
C20H28O6
Molecular Weight:
364.4327
MDL Number:
MFCD00221762
IUPAC Name:
(1S,2S,5S,8R,9S,10S,11R,15S,18R)-9,10,15,18-tetrahydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-7-one
InChI:
InChI=1S/C20H28O6/c1-9-10-4-5-11-18-8-26-20(25,19(11,14(9)22)15(10)23)16(24)13(18)17(2,3)7-6-12(18)21/h10-13,15-16,21,23-25H,1,4-8H2,2-3H3/t10-,11-,12-,13+,15+,16-,18+,19-,20+/m0/s1
InChI Key:
SDHTXBWLVGWJFT-XKCURVIJSA-N
SMILES:
C=C1[C@@H]2CC[C@H]3[C@@](C1=O)([C@@H]2O)[C@]1(O)OC[C@]23[C@@H](O)CCC([C@@H]2[C@@H]1O)(C)C
UNII:
0APJ98UCLQ
Properties
Complexity:
717
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
9
Defined Bond Stereocenter Count:
0
Exact Mass:
364.189g/mol
Formal Charge:
0
Heavy Atom Count:
26
Hydrogen Bond Acceptor Count:
6
Hydrogen Bond Donor Count:
4
Isotope Atom Count:
0
Molecular Weight:
364.438g/mol
Monoisotopic Mass:
364.189g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
107A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.1
Literature
| Title | Journal |
|---|---|
| A Redox-Sensitive and RAGE-Targeting Nanocarrier for Hepatocellular Carcinoma Therapy. | Molecular pharmaceutics 20161107 |
| Inhibition of RNA transportation induces glioma cell apoptosis via downregulation of RanGAP1 expression. | Chemico-biological interactions 20150505 |
| Interaction of oridonin with human serum albumin by isothermal titration calorimetry and spectroscopic techniques. | Chemico-biological interactions 20150505 |
| The tyrphostin AG1478 augments oridonin-induced A431 cell apoptosis by blockage of JNK MAPK and enhancement of oxidative stress. | Free radical research 20121101 |
| Nitric oxide augments oridonin-induced efferocytosis by human histocytic lymphoma U937 cells via autophagy and the NF-κB-COX-2-IL-1β pathway. | Free radical research 20121001 |
| Oridonin enhances antitumor activity of gemcitabine in pancreatic cancer through MAPK-p38 signaling pathway. | International journal of oncology 20120901 |
| Oridonin induces apoptosis and autophagy in murine fibrosarcoma L929 cells partly via NO-ERK-p53 positive-feedback loop signaling pathway. | Acta pharmacologica Sinica 20120801 |
| Synthesis and biological evaluation of novel furozan-based nitric oxide-releasing derivatives of oridonin as potential anti-tumor agents. | Molecules (Basel, Switzerland) 20120618 |
| The conversion of oridonin to spirolactone-type or enmein-type diterpenoid: synthesis and biological evaluation of ent-6,7-seco-oridonin derivatives as novel potential anticancer agents. | European journal of medicinal chemistry 20120601 |
| [Longikaurin A induces apoptosis of multiple myeloma H929 cells]. | Zhongguo shi yan xue ye xue za zhi 20120601 |
| [Anti-tumor effect of tanshinone II A, tetrandrine, honokiol, curcumin, oridonin and paeonol on leukemia cell lines]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20120501 |
| Oridonin induces apoptosis and senescence by increasing hydrogen peroxide and glutathione depletion in colorectal cancer cells. | International journal of molecular medicine 20120401 |
| In vitro and in vivo evaluation of oridonin-loaded long circulating nanostructured lipid carriers. | International journal of biological macromolecules 20120401 |
| Targeting of AML1-ETO in t(8;21) leukemia by oridonin generates a tumor suppressor-like protein. | Science translational medicine 20120328 |
| Study on the autophagy of prostate cancer PC-3 cells induced by oridonin. | Anatomical record (Hoboken, N.J. : 2007) 20120301 |
| Autophagy enhanced phagocytosis of apoptotic cells by oridonin-treated human histocytic lymphoma U937 cells. | Archives of biochemistry and biophysics 20120201 |
| Biodegradable self-assembled MPEG-PCL micelles for hydrophobic oridonin delivery in vitro. | Journal of biomedical nanotechnology 20120201 |
| Synergistic antitumor activity of oridonin and arsenic trioxide on hepatocellular carcinoma cells. | International journal of oncology 20120101 |
| Autophagy counteracts apoptosis in human multiple myeloma cells exposed to oridonin in vitro via regulating intracellular ROS and SIRT1. | Acta pharmacologica Sinica 20120101 |
| RGD-modified poly(D,L-lactic acid) nanoparticles enhance tumor targeting of oridonin. | International journal of nanomedicine 20120101 |
| Oridonin nanosuspension was more effective than free oridonin on G2/M cell cycle arrest and apoptosis in the human pancreatic cancer PANC-1 cell line. | International journal of nanomedicine 20120101 |
| Optimisation of an ultrasound-assisted extraction followed by RP-HPLC separation for the simultaneous determination of oleanolic acid, ursolic acid and oridonin content in Rabdosia rubescens. | Phytochemical analysis : PCA 20120101 |
| Oridonin up-regulates expression of P21 and induces autophagy and apoptosis in human prostate cancer cells. | International journal of biological sciences 20120101 |
| Galactose-decorated pH-responsive nanogels for hepatoma-targeted delivery of oridonin. | Biomacromolecules 20111212 |
| [Study on pharmacokinetics of oridonin in mice]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20111201 |
| Oridonin nanosuspension enhances anti-tumor efficacy in SMMC-7721 cells and H22 tumor bearing mice. | Colloids and surfaces. B, Biointerfaces 20111015 |
| Reactive oxygen species contribute to oridonin-induced apoptosis and autophagy in human cervical carcinoma HeLa cells. | Acta pharmacologica Sinica 20111001 |
| Isolation and purification of oridonin from the whole plant of Isodon rubescens by high-speed counter-current chromatography. | Molecules (Basel, Switzerland) 20110914 |
| Sensitization to TRAIL-induced apoptosis in human neuroblastoma SK-N-AS cells by NF-κB inhibitors is dependent on reactive oxygen species (ROS). | Journal of neuro-oncology 20110901 |
| Oridonin induced the apoptosis of PC-3 cells and its mechanism. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20110801 |
| Stimulation of suicidal erythrocyte death by oridonin. | Archives of biochemistry and biophysics 20110701 |
| Synthesis and revision of stereochemistry of rubescensin S. | Organic & biomolecular chemistry 20110621 |
| Development and in-vivo assessment of the bioavailability of oridonin solid dispersions by the gas anti-solvent technique. | International journal of pharmaceutics 20110615 |
| Proteomic and functional analyses reveal the potential involvement of endoplasmic reticulum stress and α-CP1 in the anticancer activities of oridonin in HepG2 cells. | Integrative cancer therapies 20110601 |
| Chitosan-g-poly(N-isopropylacrylamide) based nanogels for tumor extracellular targeting. | International journal of pharmaceutics 20110516 |
| Growth inhibition and induction of apoptosis in MCF-7 breast cancer cells by oridonin nanosuspension. | Drug delivery 20110501 |
| Oridonin: An active diterpenoid targeting cell cycle arrest, apoptotic and autophagic pathways for cancer therapeutics. | The international journal of biochemistry & cell biology 20110501 |
| Combined activity of oridonin and wogonin in advanced-stage ovarian cancer cells: sensitivity of ovarian cancer cells to phyto-active chemicals. | Cell biology and toxicology 20110401 |
| Downregulation of AP-1 gene expression is an initial event in the oridonin-mediated inhibition of colorectal cancer: studies in vitro and in vivo. | Journal of gastroenterology and hepatology 20110401 |
| Proteomic identification of proteins involved in the anticancer activities of oridonin in HepG2 cells. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20110115 |
| A novel analysis method for diterpenoids in rat plasma by liquid chromatography-electrospray ionization mass spectrometry. | Analytical biochemistry 20101201 |
| [Autophagy of prostate cancer PC-3 cells under the induction of oridonin]. | Zhonghua yi xue za zhi 20101116 |
| Oridonin induces G2/M cell cycle arrest and apoptosis through MAPK and p53 signaling pathways in HepG2 cells. | Oncology reports 20100901 |
| Inhibition of EGFR signaling augments oridonin-induced apoptosis in human laryngeal cancer cells via enhancing oxidative stress coincident with activation of both the intrinsic and extrinsic apoptotic pathways. | Cancer letters 20100828 |
| Induction of G(2)/M phase arrest and apoptosis by oridonin in human laryngeal carcinoma cells. | Journal of natural products 20100625 |
| Preparation and characteristics of oridonin-loaded nanostructured lipid carriers as a controlled-release delivery system. | Journal of microencapsulation 20100501 |
| Apoptosis inducing and differentiation enhancement effect of oridonin on the all-trans-retinoic acid-sensitive and -resistant acute promyelocytic leukemia cells. | International journal of laboratory hematology 20100201 |
| Sigma-1 receptors regulate Bcl-2 expression by reactive oxygen species-dependent transcriptional regulation of nuclear factor kappaB. | The Journal of pharmacology and experimental therapeutics 20100201 |
| Effects of oridonin nanosuspension on cell proliferation and apoptosis of human prostatic carcinoma PC-3 cell line. | International journal of nanomedicine 20100101 |
| Oridonin induces apoptosis and senescence in colorectal cancer cells by increasing histone hyperacetylation and regulation of p16, p21, p27 and c-myc. | BMC cancer 20100101 |
| [Empirical study of oridonin-induced gastric cancer cells MKN45 apoptosis]. | Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20091101 |
| Oridonin induces G2/M arrest and apoptosis via activating ERK-p53 apoptotic pathway and inhibiting PTK-Ras-Raf-JNK survival pathway in murine fibrosarcoma L929 cells. | Archives of biochemistry and biophysics 20091001 |
| [Preparation and characterization of oridonin submicron emulsions]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091001 |
| In vitro and in vivo antitumor activity of oridonin nanosuspension. | International journal of pharmaceutics 20090908 |
| NF-kappab facilitates oridonin-induced apoptosis and autophagy in HT1080 cells through a p53-mediated pathway. | Archives of biochemistry and biophysics 20090901 |
| Effects and mechanism of oridonin on pulmonary hypertension induced by chronic hypoxia-hypercapnia in rats. | Chinese medical journal 20090620 |
| Molecular mechanisms of oridonin-induced apoptosis and autophagy in murine fibrosarcoma L929 cells. | Autophagy 20090401 |
| Multiple-modulation effects of Oridonin on the production of proinflammatory cytokines and neurotrophic factors in LPS-activated microglia. | International immunopharmacology 20090301 |
| Autophagy inhibits reactive oxygen species-mediated apoptosis via activating p38-nuclear factor-kappa B survival pathways in oridonin-treated murine fibrosarcoma L929 cells. | The FEBS journal 20090301 |
| Involvement of PKC signal pathways in oridonin-induced autophagy in HeLa cells: a protective mechanism against apoptosis. | Biochemical and biophysical research communications 20090109 |
| Optimization and in situ intestinal absorption of self-microemulsifying drug delivery system of oridonin. | International journal of pharmaceutics 20090105 |
| [Study on stability of oridonin solution]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090101 |
| The effect of stealth liposomes on pharmacokinetics, tissue distribution and anti-tumor activity of oridonin. | PDA journal of pharmaceutical science and technology 20090101 |
| Oridonin confers protection against arsenic-induced toxicity through activation of the Nrf2-mediated defensive response. | Environmental health perspectives 20080901 |
| Caspase inhibition augmented oridonin-induced cell death in murine fibrosarcoma l929 by enhancing reactive oxygen species generation. | Journal of pharmacological sciences 20080901 |
| [Release kinetics of oridonin self-microemulsifying drug delivery system in vitro]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080901 |
| Synthesis and biological evaluation of novel 1-O- and 14-O-derivatives of oridonin as potential anticancer drug candidates. | Bioorganic & medicinal chemistry letters 20080815 |
| Reactive oxygen species mediate oridonin-induced HepG2 apoptosis through p53, MAPK, and mitochondrial signaling pathways. | Journal of pharmacological sciences 20080801 |
| Apoptosis-suppressing and autophagy-promoting effects of calpain on oridonin-induced L929 cell death. | Archives of biochemistry and biophysics 20080715 |
| Oridonin-loaded poly(epsilon-caprolactone)-poly(ethylene oxide)-poly(epsilon-caprolactone) copolymer nanoparticles: preparation, characterization, and antitumor activity on mice with transplanted hepatoma. | Journal of drug targeting 20080701 |
| An HPLC method for determination of oridonin in rabbits using isopsoralen as an internal standard and its application to pharmacokinetic studies for oridonin-loaded nanoparticles. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080615 |
| Characterization and in vivo evaluation of an inclusion complex of oridonin and 2-hydroxypropyl-beta-cyclodextrin. | Drug development and industrial pharmacy 20080601 |
| Preparation and evaluation of self-microemulsifying drug delivery system of oridonin. | International journal of pharmaceutics 20080501 |
| Studies on pharmacokinetics and tissue distribution of oridonin nanosuspensions. | International journal of pharmaceutics 20080501 |
| Oridonin promotes CD4+/CD25+ Treg differentiation, modulates Th1/Th2 balance and induces HO-1 in rat splenic lymphocytes. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20080401 |
| Down-regulation of androgen-receptor and PSA by phytochemicals. | International journal of oncology 20080201 |
| [Inhibitory effect of Oridonin injection on heterotransplanted gastric adenocarcinoma in nude mice and its mechanism]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20080201 |
| Oridonin induces human epidermoid carcinoma A431 cell apoptosis through tyrosine kinase and mitochondrial pathway. | Journal of Asian natural products research 20080101 |
| Oridonin induces human melanoma A375-S2 cell death partially through inhibiting insulin-like growth factor 1 receptor signaling. | Journal of Asian natural products research 20080101 |
| Oridonin induced autophagy in human cervical carcinoma HeLa cells through Ras, JNK, and P38 regulation. | Journal of pharmacological sciences 20071201 |
| Preparation and characterization of an oridonin nanosuspension for solubility and dissolution velocity enhancement. | Drug development and industrial pharmacy 20071201 |
| Oridonin induces apoptosis via PI3K/Akt pathway in cervical carcinoma HeLa cell line. | Acta pharmacologica Sinica 20071101 |
| Authentication and chemical study of isodonis herba and isodonis extracts. | Chemical & pharmaceutical bulletin 20071101 |
| [Determination of oridonin and rosemarinic acid in Rabdosia rubescens by HPLC]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20071101 |
| [Effects of Oridonin on proliferation in human nasopharyngeal carcinoma line CNE 2 in vitro]. | Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery 20071001 |
| Inactivation of ras and changes of mitochondrial membrane potential contribute to oridonin-induced autophagy in a431 cells. | Journal of pharmacological sciences 20070901 |
| Studies on the cell-immunosuppressive mechanism of Oridonin from Isodon serra. | International immunopharmacology 20070701 |
| P53-mediated cell cycle arrest and apoptosis through a caspase-3- independent, but caspase-9-dependent pathway in oridonin-treated MCF-7 human breast cancer cells. | Acta pharmacologica Sinica 20070701 |
| Effects of oridonin on proliferation of HT29 human colon carcinoma cell lines both in vitro and in vivo in mice. | Die Pharmazie 20070601 |
| Autophagy preceded apoptosis in oridonin-treated human breast cancer MCF-7 cells. | Biological & pharmaceutical bulletin 20070501 |
| Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo. | Blood 20070415 |
| Back to the future of oridonin: again, compound from medicinal herb shows potent antileukemia efficacies in vitro and in vivo. | Cell research 20070401 |
| Effective two-dimensional counter-current chromatographic method for simultaneous isolation and purification of oridonin and ponicidin from the crude extract of Rabdosia rubescens. | Journal of chromatography. A 20070330 |
| Oridonin induced apoptosis through Akt and MAPKs signaling pathways in human osteosarcoma cells. | Cancer biology & therapy 20070201 |
| Oridonin inhibited the tyrosine kinase activity and induced apoptosis in human epidermoid carcinoma A431 cells. | Biological & pharmaceutical bulletin 20070201 |
| Studies on the oridonin-loaded poly(D,L-lactic acid) nanoparticles in vitro and in vivo. | International journal of biological macromolecules 20070130 |
| Determination of oridonin in rat plasma by reverse-phase high-performance liquid chromatography. | Journal of pharmaceutical and biomedical analysis 20070117 |
| Oridonin-induced A431 cell apoptosis partially through blockage of the Ras/Raf/ERK signal pathway. | Journal of pharmacological sciences 20070101 |
| [Mechanism of downregulation of apoptosis by autophagy induced by oridonin in HeLa cells]. | Yao xue xue bao = Acta pharmaceutica Sinica 20070101 |
| Pharmacokinetic behaviors and oral bioavailability of oridonin in rat plasma. | Acta pharmacologica Sinica 20061201 |
| Fibroblast growth factor-2 suppresses oridonin-induced L929 apoptosis through extracellular signal-regulated kinase-dependent and phosphatidylinositol 3-kinase-independent pathway. | Journal of pharmacological sciences 20061101 |
| [Change of Bcl-2 expression and telomerase during apoptosis induced by oridonin on human hepatocelluar carcinoma cells]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20061101 |
| Fas/FasL signaling allows extracelluar-signal regulated kinase to regulate cytochrome c release in oridonin-induced apoptotic U937 cells. | Biological & pharmaceutical bulletin 20060901 |
| A rapid HPLC/ESI-MS method for the quantitative determination of oridonin in rat plasma. | Die Pharmazie 20060901 |
| Augmentation of oridonin-induced apoptosis observed with reduced autophagy. | Journal of pharmacological sciences 20060701 |
| Celastrol, a triterpene extracted from the Chinese 'Thunder of God Vine,' is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice. | Cancer research 20060501 |
| Roles of Ras and extracellular signal-regulated kinase-dependent IkappaBalpha degradation in oridonin-enhanced phagocytosis of apoptotic cells by human macrophage-like U937 cells. | International immunopharmacology 20060201 |
| Antiproliferation effects of oridonin on HPB-ALL cells and its mechanisms of action. | American journal of hematology 20060201 |
| Isolation and purification of oridonin from Rabdosia rubescens using upright counter-current chromatography. | Journal of separation science 20060201 |
| The effects of oridonin on cell growth, cell cycle, cell migration and differentiation in melanoma cells. | Journal of ethnopharmacology 20060116 |
| A comparison of the signal pathways between the TNF alpha- and oridonin-induced murine L929 fibrosarcoma cell death. | Acta medica Okayama 20051201 |
| [Oridonin induced U937 cell apoptosis through ERK pathway]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20051201 |
| Differential control of growth, cell cycle progression, and expression of NF-kappaB in human breast cancer cells MCF-7, MCF-10A, and MDA-MB-231 by ponicidin and oridonin, diterpenoids from the chinese herb Rabdosia rubescens. | Biochemical and biophysical research communications 20051111 |
| Bcl-2 up-regulation and P-p53 down-regulation account for the low sensitivity of murine L929 fibrosarcoma cells to oridonin-induced apoptosis. | Biological & pharmaceutical bulletin 20051101 |
| Activation of phosphoinositide 3-kinase, protein kinase C, and extracellular signal-regulated kinase is required for oridonin-enhanced phagocytosis of apoptotic bodies in human macrophage-like U937 cells. | Journal of pharmacological sciences 20050801 |
| [The tissue distribution in mice and pharmacokinetics in rabbits of oridonin-solid lipid nanoparticles]. | Yao xue xue bao = Acta pharmaceutica Sinica 20050601 |
| Oridonin, a diterpenoid purified from Rabdosia rubescens, inhibits the proliferation of cells from lymphoid malignancies in association with blockade of the NF-kappa B signal pathways. | Molecular cancer therapeutics 20050401 |
| Apoptotic effect of oridonin on NB4 cells and its mechanism. | Leukemia & lymphoma 20050401 |
| The cytostatic and cytotoxic effects of oridonin (Rubescenin), a diterpenoid from Rabdosia rubescens, on tumor cells of different lineage. | International journal of oncology 20050301 |
| Oridonin enhances phagocytosis of UV-irradiated apoptotic U937 cells. | Biological & pharmaceutical bulletin 20050301 |
| Oridonin-induced apoptosis in leukemia K562 cells and its mechanism. | Neoplasma 20050101 |
| Antiproliferation effects of oridonin on HL-60 cells. | Annals of hematology 20041101 |
| [Regulation of telomerase activity and cell cycle of K562 cells by oridonin]. | Yao xue xue bao = Acta pharmaceutica Sinica 20041101 |
| Oridonin induces a caspase-independent but mitochondria- and MAPK-dependent cell death in the murine fibrosarcoma cell line L929. | Biological & pharmaceutical bulletin 20041001 |
| Cytochrome c release from oridonin-treated apoptotic A375-S2 cells is dependent on p53 and extracellular signal-regulated kinase activation. | Journal of pharmacological sciences 20041001 |
| Oridonin induced A375-S2 cell apoptosis via bax-regulated caspase pathway activation, dependent on the cytochrome c/caspase-9 apoptosome. | Journal of Asian natural products research 20040601 |
| Anti-proliferation effect of oridonin on HL-60 cells and its mechanism. | Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20040601 |
| Oridonin induces apoptosis of HeLa cells via altering expression of Bcl-2/Bax and activating caspase-3/ICAD pathway. | Acta pharmacologica Sinica 20040501 |
| Ponicidin and oridonin are responsible for the antiangiogenic activity of Rabdosia rubescens, a constituent of the herbal supplement PC SPES. | Journal of natural products 20040101 |
| Anti-proliferative effects of oridonin on SPC-A-1 cells and its mechanism of action. | The Journal of international medical research 20040101 |
| Oridonin induces growth inhibition and apoptosis of a variety of human cancer cells. | International journal of oncology 20031001 |
| Taibaijaponicains C and D: two new diterpenoids from Isodon japonica. | Planta medica 20020501 |
| Antibacterial activity of trichorabdal A from Rabdosia trichocarpa against Helicobacter pylori. | Zentralblatt fur Bakteriologie : international journal of medical microbiology 19970601 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.