200,000+ products from a single source!
sales@angenechem.com
288-16-4 | 1,2-Thiazole
CAS No: 288-16-4 Catalog No: AG002WJF MDL No:MFCD00020818
Product Description
Catalog Number:
AG002WJF
Chemical Name:
1,2-Thiazole
CAS Number:
288-16-4
Molecular Formula:
C3H3NS
Molecular Weight:
85.1276
MDL Number:
MFCD00020818
IUPAC Name:
1,2-thiazole
InChI:
InChI=1S/C3H3NS/c1-2-4-5-3-1/h1-3H
InChI Key:
ZLTPDFXIESTBQG-UHFFFAOYSA-N
SMILES:
c1ccns1
UNII:
38FAO14250
Properties
Complexity:
30.1
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
84.999g/mol
Formal Charge:
0
Heavy Atom Count:
5
Hydrogen Bond Acceptor Count:
2
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
85.124g/mol
Monoisotopic Mass:
84.999g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
41.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1
Literature
| Title | Journal |
|---|---|
| Isothiazole and isoxazole fused pyrimidones as PDE7 inhibitors: SAR and pharmacokinetic evaluation. | Bioorganic & medicinal chemistry letters 20120501 |
| Lurasidone hydro-chloride. | Acta crystallographica. Section E, Structure reports online 20120501 |
| Diarylheterocycle core ring features effect in selective COX-1 inhibition. | ChemMedChem 20120401 |
| 3-Phenyl-5-isothiazole carboxamides with potent mGluR1 antagonist activity. | Bioorganic & medicinal chemistry letters 20120401 |
| 3D-QSAR and molecular docking studies on substituted isothiazole analogs as inhibitors against MEK-1 kinase. | Chemical biology & drug design 20120101 |
| Cytotoxic effects of chemotherapeutic drugs and heterocyclic compounds at application on the cells of primary culture of neuroepithelium tumors. | Medicinal chemistry (Shariqah (United Arab Emirates)) 20120101 |
| Application of 2-trichloromethylbenzimidazole in analytical chemistry: a highly selective chromogenic reagent for thin-layer chromatography and some other analytical uses. | Journal of analytical methods in chemistry 20120101 |
| Critical appraisal of lurasidone in the management of schizophrenia. | Neuropsychiatric disease and treatment 20120101 |
| Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer. | PloS one 20120101 |
| Bioactivation of isothiazoles: minimizing the risk of potential toxicity in drug discovery. | Chemical research in toxicology 20101115 |
| In silico exploration for identifying structure-activity relationship of MEK inhibition and oral bioavailability for isothiazole derivatives. | Chemical biology & drug design 20101101 |
| Ligand-exchange processes on solvated zinc cations: water exchange on [Zn(H2O)4(L)]2+.2H2O (L=heterocyclic ligand). | Chemistry (Weinheim an der Bergstrasse, Germany) 20100625 |
| Novel derivatives of 1,3,4-oxadiazoles are potent mitostatic agents featuring strong microtubule depolymerizing activity in the sea urchin embryo and cell culture assays. | European journal of medicinal chemistry 20100501 |
| Synthesis and pharmacological evaluation of thiazole and isothiazole derived apomorphines. | Archiv der Pharmazie 20091001 |
| Synthesis of novel vanillin derivatives containing isothiazole moieties and its synergistic effect in mixtures with insecticides. | Natural product communications 20090901 |
| Synthesis and immunomodulatory activites of new 5-hydrazino-3-methyl-4-isothiazolecarboxylic acid ethyl esters. | Acta poloniae pharmaceutica 20090101 |
| New amides of 5-(4-chlorobenzoyl)aminoorotic acid: their synthesis and biological activity. | Archiv der Pharmazie 20081101 |
| Efficient synthesis and utilization of phenyl-substituted heteroaromatic carboxylic acids as aryl diketo acid isosteres in the design of novel HIV-1 integrase inhibitors. | Bioorganic & medicinal chemistry letters 20080815 |
| Synthesis and pharmacology of glutamate receptor ligands: new isothiazole analogues of ibotenic acid. | Organic & biomolecular chemistry 20070207 |
| New derivatives of 5-amino-3-methyl-4-isothiazolecarboxylic acid and their immunological activity. | Acta poloniae pharmaceutica 20070101 |
| Isothiazole derivatives as antiviral agents. | Antiviral chemistry & chemotherapy 20070101 |
| New regiospecific isothiazole C-C coupling chemistry. | Organic & biomolecular chemistry 20061007 |
| Discovery of novel isothiazole inhibitors of the TrkA kinase: structure-activity relationship, computer modeling, optimization, and identification of highly potent antagonists. | Bioorganic & medicinal chemistry letters 20060701 |
| New isothiazole derivatives: synthesis, reactivity, physicochemical properties and pharmacological activity. | Archiv der Pharmazie 20060701 |
| Isothiazole dioxide derivative 6n inhibits vascular smooth muscle cell proliferation and protein farnesylation. | Biochemical pharmacology 20051205 |
| Isothiazole derivatives as novel HIV replication inhibitors. | Antiviral chemistry & chemotherapy 20040701 |
| Ibotenic acid and thioibotenic acid: a remarkable difference in activity at group III metabotropic glutamate receptors. | European journal of pharmacology 20040223 |
| Pharmacological characterization of CP-547,632, a novel vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for cancer therapy. | Cancer research 20031101 |
| Regiospecific Suzuki coupling of 3,5-dichloroisothiazole-4-carbonitrile. | Organic & biomolecular chemistry 20030821 |
| Novel synthesis and reactions of 5,7-dialkyl-4,6-dioxo-4,5,6,7-tetrahydro- isothiazolo[3,4,-d]pyrimidine-3-carbonitriles and 6-methyl-4-oxo-4H-1-aza-5-oxa-2- thiaindene-3-carbonitrile. | Organic letters 20030220 |
| [Biological activity of the isothiazole derivatives]. | Postepy higieny i medycyny doswiadczalnej 20030101 |
| [Synthesis and monolayer behaviors of 4-methyl-5-hydroxy-ethyl isothiazole stearic ester]. | Guang pu xue yu guang pu fen xi = Guang pu 20021201 |
| Isothiazole dioxides: synthesis and inhibition of Trypanosoma brucei protein farnesyltransferase. | Bioorganic & medicinal chemistry letters 20020819 |
| Synthesis of new 3-methylthio-5-aryl-4-isothiazolecarbonitriles with broad antiviral spectrum. | Antiviral research 20020801 |
| Efficient synthesis of fused isothiazolo C-nucleosides. III. Synthesis of substituted isothiazol. | Nucleosides, nucleotides & nucleic acids 20010301 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.