200,000+ products from a single source!
sales@angenechem.com
Home > Other Building Blocks > 28585-51-5
28585-51-5 | Thymidine, 2-thio-
CAS No: 28585-51-5 Catalog No: AG002VQY MDL No:
Product Description
Catalog Number:
AG002VQY
Chemical Name:
Thymidine, 2-thio-
CAS Number:
28585-51-5
Molecular Formula:
C10H14N2O4S
Molecular Weight:
258.2942
IUPAC Name:
1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidenepyrimidin-4-one
InChI:
InChI=1S/C10H14N2O4S/c1-5-3-12(10(17)11-9(5)15)8-2-6(14)7(4-13)16-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,17)/t6-,7+,8+/m0/s1
InChI Key:
PISWNSOQFZRVJK-XLPZGREQSA-N
SMILES:
OC[C@H]1O[C@H](C[C@@H]1O)n1cc(C)c(=O)[nH]c1=S
Properties
Complexity:
385
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
3
Defined Bond Stereocenter Count:
0
Exact Mass:
258.067g/mol
Formal Charge:
0
Heavy Atom Count:
17
Hydrogen Bond Acceptor Count:
5
Hydrogen Bond Donor Count:
3
Isotope Atom Count:
0
Molecular Weight:
258.292g/mol
Monoisotopic Mass:
258.067g/mol
Rotatable Bond Count:
2
Topological Polar Surface Area:
114A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.6
Literature
| Title | Journal |
|---|---|
| Self-Avoiding Molecular Recognition Systems (SAMRS). | Nucleic acids symposium series (2004) 20080101 |
| Stability and mismatch discrimination of DNA duplexes containing 2,6-diaminopurine and 2-thiothymidine locked nucleic acid bases. | Nucleic acids symposium series (2004) 20080101 |
| Triplex forming ability of oligonucleotides containing 2'-O-methyl-2-thiouridine or 2-thiothymidine. | Bioorganic & medicinal chemistry letters 20060615 |
| Enhanced base pairing and replication efficiency of thiothymidines, expanded-size variants of thymidine. | Journal of the American Chemical Society 20060118 |
| Role of histidine-85 in the catalytic mechanism of thymidine phosphorylase as assessed by targeted molecular dynamics simulations and quantum mechanical calculations. | Biochemistry 20040120 |
| Synthesis and antiherpesvirus activities of 5-alkyl-2-thiopyrimidine nucleoside analogues. | Antiviral chemistry & chemotherapy 20020301 |
| Anti-herpesvirus activities and cytotoxicities of 2-thiopyrimidine nucleoside analogues in vitro. | Antiviral chemistry & chemotherapy 19990701 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.