CAS 281-23-2 | Adamantane | CAS Number 281-23-2

Title	Journal
SGLT2-inhibitor and DPP-4 inhibitor improve brain function via attenuating mitochondrial dysfunction, insulin resistance, inflammation, and apoptosis in HFD-induced obese rats.	Toxicology and applied pharmacology 20171015
Soluble epoxide hydrolase inhibitor AUDA decreases bleomycin-induced pulmonary toxicity in mice by inhibiting the p38/Smad3 pathways.	Toxicology 20170815
A novel JAK inhibitor, peficitinib, demonstrates potent efficacy in a rat adjuvant-induced arthritis model.	Journal of pharmacological sciences 20170101
Ezrin Inhibition Up-regulates Stress Response Gene Expression.	The Journal of biological chemistry 20160617
Antimalarial activity of artefenomel (OZ439), a novel synthetic antimalarial endoperoxide, in patients with Plasmodium falciparum and Plasmodium vivax malaria: an open-label phase 2 trial.	The Lancet. Infectious diseases 20160101
A phase 2a randomized, double-blind, placebo-controlled, sequential dose-escalation study to evaluate the efficacy and safety of ASP015K, a novel Janus kinase inhibitor, in patients with moderate-to-severe psoriasis.	The British journal of dermatology 20150901
Effects of bioisosteric fluorine in synthetic cannabinoid designer drugs JWH-018, AM-2201, UR-144, XLR-11, PB-22, 5F-PB-22, APICA, and STS-135.	ACS chemical neuroscience 20150819
Dysregulation of retinoic acid receptor diminishes hepatocyte permissiveness to hepatitis B virus infection through modulation of sodium taurocholate cotransporting polypeptide (NTCP) expression.	The Journal of biological chemistry 20150227
Saxagliptin: a novel antiparkinsonian approach.	Neuropharmacology 20150201
Pharmacological targeting of the pseudokinase Her3.	Nature chemical biology 20141201
Efficacy and safety evaluation of HSD-1 inhibitor ABT-384 in Alzheimer's disease.	Alzheimer's & dementia : the journal of the Alzheimer's Association 20141001
Peripheral and central nervous system inhibition of 11β-hydroxysteroid dehydrogenase type 1 in man by the novel inhibitor ABT-384.	Translational psychiatry 20130801
Effect of ketoconazole on the pharmacokinetics of the 11β-hydroxysteroid dehydrogenase type 1 inhibitor ABT-384 and its two active metabolites in healthy volunteers: population analysis of data from a drug-drug interaction study.	Drug metabolism and disposition: the biological fate of chemicals 20130501
Saxagliptin overview: special focus on safety and adverse effects.	Expert opinion on drug safety 20130101
Adenosine A2A receptor modulates vascular response in soluble epoxide hydrolase-null mice through CYP-epoxygenases and PPARγ.	American journal of physiology. Regulatory, integrative and comparative physiology 20130101
Exploiting adamantane as a versatile organic tecton: multicomponent catalytic cascade reactions.	Chemical communications (Cambridge, England) 20121207
A novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor, teneligliptin, improves postprandial hyperglycemia and dyslipidemia after single and repeated administrations.	European journal of pharmacology 20121205
Development of a rapid UPLC-MS/MS method for quantification of saxagliptin in rat plasma and application to pharmacokinetic study.	Biomedical chromatography : BMC 20121201
Shell cross-linking of cyclodextrin-based micelles via supramolecular chemistry for the delivery of drugs.	Macromolecular rapid communications 20121114
One-year safety, tolerability and efficacy of vildagliptin in patients with type 2 diabetes and moderate or severe renal impairment.	Diabetes, obesity & metabolism 20121101
Safety of saxagliptin: rationale for and design of a series of postmarketing observational studies.	Pharmacoepidemiology and drug safety 20121101
Adamantyl carboxamides and acetamides as potent human 11β-hydroxysteroid dehydrogenase type 1 inhibitors.	Bioorganic & medicinal chemistry 20121101
Identification of antischistosomal leads by evaluating bridged 1,2,4,5-tetraoxanes, alphaperoxides, and tricyclic monoperoxides.	Journal of medicinal chemistry 20121025
4-Oxo-1,4-dihydropyridines as selective CB₂ cannabinoid receptor ligands. Part 2: discovery of new agonists endowed with protective effect against experimental colitis.	Journal of medicinal chemistry 20121025
Synthesis and transformation of linear adamantane assemblies inside carbon nanotubes.	ACS nano 20121023
Synthesis, crystal structure and thermal properties of Ca6(C12H14O4)4(CO3)(OH)2(H2O)x--a 3D inorganic hybrid material.	Dalton transactions (Cambridge, England : 2003) 20121021
Stable silaimines with three- and four-coordinate silicon atoms.	Inorganic chemistry 20121015
The synthesis of W-O-W μ-oxo clusters by hydrolysis of tungsten aminoalkoxides and their structural characterisation.	Dalton transactions (Cambridge, England : 2003) 20121007
Eppendorf finalist. Striatal interneurons: causes of or cures for movement disorders?	Science (New York, N.Y.) 20121005
Quantitative model of the relationship between dipeptidyl peptidase-4 (DPP-4) inhibition and response: meta-analysis of alogliptin, saxagliptin, sitagliptin, and vildagliptin efficacy results.	Journal of clinical pharmacology 20121001
Effects of saxagliptin and sitagliptin on glycaemic control and pancreatic β-cell mass in a streptozotocin-induced mouse model of type 2 diabetes.	Diabetes, obesity & metabolism 20121001
Reduction of oxidative stress and inflammation by blunting daily acute glucose fluctuations in patients with type 2 diabetes: role of dipeptidyl peptidase-IV inhibition.	Diabetes care 20121001
Add-on therapies to metformin in type 2 diabetes: what modulates the respective decrements in postprandial and basal glucose?	Diabetes technology & therapeutics 20121001
Continuous glucose profiles with vildagliptin versus sitagliptin in add-on to metformin: results from the randomized Optima study.	Diabetes & metabolism 20121001
DPP4 inhibitor vildagliptin preserves β-cell mass through amelioration of endoplasmic reticulum stress in C/EBPB transgenic mice.	Journal of molecular endocrinology 20121001
Vildagliptin reduces glucagon during hyperglycemia and sustains glucagon counterregulation during hypoglycemia in type 1 diabetes.	The Journal of clinical endocrinology and metabolism 20121001
Pharmacological inhibition of soluble epoxide hydrolase provides cardioprotection in hyperglycemic rats.	American journal of physiology. Heart and circulatory physiology 20121001
Assembly of water-soluble, dynamic, covalent container molecules and their application in the room-temperature stabilization of protoadamantene.	Chemistry (Weinheim an der Bergstrasse, Germany) 20121001
Effects of saxagliptin added to sub-maximal doses of metformin compared with uptitration of metformin in type 2 diabetes: the PROMPT study.	Current medical research and opinion 20121001
Chronic DPP-IV inhibition with PKF-275-055 attenuates inflammation and improves gene expressions responsible for insulin secretion in streptozotocin induced diabetic rats.	European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120929
Exceptional chemical properties of Sc@C(2v)(9)-C82 probed with adamantylidene carbene.	Journal of the American Chemical Society 20120919
Anti-diabetic and anti-adipogenic effects of a novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor in the diet-induced obese mice.	European journal of pharmacology 20120915
Effects of long-term treatment with the dipeptidyl peptidase-4 inhibitor vildagliptin on islet endocrine cells in non-obese type 2 diabetic Goto-Kakizaki rats.	European journal of pharmacology 20120915
A supramolecular route towards core-shell polymeric microspheres in water via cucurbit[8]uril complexation.	Chemical communications (Cambridge, England) 20120911
Surface modified liposomes by mannosylated conjugates anchored via the adamantyl moiety in the lipid bilayer.	Biochimica et biophysica acta 20120901
Regioselective synthesis of 1,3,5-adamantanetriol from 1,3-adamantanediol using Kitasatospora cells.	Biotechnology letters 20120901
DPP4 inhibition improves functional outcome after renal ischemia-reperfusion injury.	American journal of physiology. Renal physiology 20120901
Dipeptidyl-peptidase-IV by cleaving neuropeptide Y induces lipid accumulation and PPAR-γ expression.	Peptides 20120901
H1N1 2009 pandemic influenza virus: resistance of the I223R neuraminidase mutant explained by kinetic and structural analysis.	PLoS pathogens 20120901
Calix[4]tubes: an approach to functionalization.	Chemistry (Weinheim an der Bergstrasse, Germany) 20120827
Effects of trehalose polycation end-group functionalization on plasmid DNA uptake and transfection.	Biomacromolecules 20120813
Ligand effects on hydrogen atom transfer from hydrocarbons to three-coordinate iron imides.	Inorganic chemistry 20120806
Enhanced cell cycle perturbation and apoptosis mediate the synergistic effects of ST1926 and ATRA in neuroblastoma preclinical models.	Investigational new drugs 20120801
The efficacy and safety of vildagliptin in patients with type 2 diabetes: a meta-analysis of randomized clinical trials.	Journal of clinical pharmacy and therapeutics 20120801
Efficacy and tolerability of vildagliptin as add-on therapy to metformin in Chinese patients with type 2 diabetes mellitus.	Diabetes, obesity & metabolism 20120801
Synthesis and antimicrobial evaluation of novel platensimycin analogues.	Archiv der Pharmazie 20120801
Depolarization potentiates TRAIL-induced apoptosis in human melanoma cells: role for ATP-sensitive K+ channels and endoplasmic reticulum stress.	International journal of oncology 20120801
Cardioprotective effects of metformin and vildagliptin in adult rats with insulin resistance induced by a high-fat diet.	Endocrinology 20120801
Novel polycyclic 'cage'-1,2-diamines as potential anti-tuberculosis agents.	European journal of medicinal chemistry 20120801
Uranium(III)-mediated C-C-coupling of terminal alkynes: formation of dinuclear uranium(IV) vinyl complexes.	Journal of the American Chemical Society 20120801
Ortho-carbaborane derivatives of indomethacin as cyclooxygenase (COX)-2 selective inhibitors.	Bioorganic & medicinal chemistry 20120801
5-(Adamantan-1-yl)-3-[(2-meth-oxy-eth-yl)sulfan-yl]-4-phenyl-4H-1,2,4-triazole.	Acta crystallographica. Section E, Structure reports online 20120801
3-(Adamantan-1-yl)-4-ethyl-1-[(4-phenyl-piperazin-1-yl)meth-yl]-1H-1,2,4-triazole-5(4H)-thione.	Acta crystallographica. Section E, Structure reports online 20120801
5-(Adamantan-1-yl)-3-(benzyl-sulfan-yl)-4-methyl-4H-1,2,4-triazole.	Acta crystallographica. Section E, Structure reports online 20120801
Overcoming bioanalytical challenges in an Onglyza(®) intravenous [(14)C]microdose absolute bioavailability study with accelerator MS.	Bioanalysis 20120801
Jahn-Teller distortion of hydrocarbon cations probed by infrared photodissociation spectroscopy.	Angewandte Chemie (International ed. in English) 20120723
Oxidation state delineation via U L(III)-edge XANES in a series of isostructural uranium coordination complexes.	Inorganic chemistry 20120716
Long-chain cationic derivatives of PTA (1,3,5-triaza-7-phosphaadamantane) as new components of potential non-viral vectors.	International journal of pharmaceutics 20120715
Synthesis of U(IV) imidos from Tp2U(CH2Ph) (Tp = hydrotris(3,5-dimethylpyrazolyl)borate) by extrusion of bibenzyl.	Dalton transactions (Cambridge, England : 2003) 20120714
Selective mode of action of guanidine-containing non-peptides at human NPFF receptors.	Journal of medicinal chemistry 20120712
Cost-effectiveness of saxagliptin (Onglyza®) in type 2 diabetes in Sweden.	Primary care diabetes 20120701
Effects of PKF275-055, a dipeptidyl peptidase-4 inhibitor, on the development of atherosclerotic lesions in apolipoprotein E-null mice.	Metabolism: clinical and experimental 20120701
Effect of the calcium sensing receptor on rat bone marrow-derived mesenchymal stem cell proliferation through the ERK1/2 pathway.	Molecular biology reports 20120701
A competitive chemiluminescence enzyme immunoassay for rapid and sensitive determination of enrofloxacin.	Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120701
Characterization of the in vitro and in vivo metabolism and disposition and cytochrome P450 inhibition/induction profile of saxagliptin in human.	Drug metabolism and disposition: the biological fate of chemicals 20120701
New adamantane derivatives with sigma affinity and antiproliferative activity.	Medicinal chemistry (Shariqah (United Arab Emirates)) 20120701
Pharmacokinetic study of saxagliptin in healthy Chinese subjects.	Clinical drug investigation 20120701
Drug-induced hypoglycaemia in type 2 diabetes.	Expert opinion on drug safety 20120701
5-(Adamantan-1-yl)-3-[(4-benzyl-piperazin-1-yl)meth-yl]-1,3,4-oxadiazole-2(3H)-thione.	Acta crystallographica. Section E, Structure reports online 20120701
N'-(Adamantan-2-yl-idene)benzo-hydrazide.	Acta crystallographica. Section E, Structure reports online 20120701
Sphingosine kinase isoforms as a therapeutic target in endocrine therapy resistant luminal and basal-A breast cancer.	Experimental biology and medicine (Maywood, N.J.) 20120701
[Effects of ionotropic glutamate receptor channel blockers ON sleep-waking organization in rats].	Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20120701
Vildagliptin inhibits oxidative stress and vascular damage in streptozotocin-induced diabetic rats.	International journal of cardiology 20120628
Bulky adamantanethiolate and cyclohexanethiolate ligands favor smaller gold nanoparticles with altered discrete sizes.	ACS nano 20120626
Nanodiamonds in sugar rings: an experimental and theoretical investigation of cyclodextrin-nanodiamond inclusion complexes.	Organic & biomolecular chemistry 20120621
Depigmenting activities of kojic acid derivatives without tyrosinase inhibitory activities.	Bioorganic & medicinal chemistry letters 20120615
7-Azabicyclo[2.2.1]heptane as a scaffold for the development of selective sigma-2 (σ2) receptor ligands.	Bioorganic & medicinal chemistry letters 20120615
Brain-derived neurotrophic factor activation of CaM-kinase kinase via transient receptor potential canonical channels induces the translation and synaptic incorporation of GluA1-containing calcium-permeable AMPA receptors.	The Journal of neuroscience : the official journal of the Society for Neuroscience 20120613
Small organometallic compounds as antibacterial agents.	Dalton transactions (Cambridge, England : 2003) 20120607
Mechanically induced chemiluminescence from polymers incorporating a 1,2-dioxetane unit in the main chain.	Nature chemistry 20120603
Effects of vildagliptin on postprandial markers of bone resorption and calcium homeostasis in recently diagnosed, well-controlled type 2 diabetes patients.	Journal of diabetes 20120601
Saxagliptin and sitagliptin in adult patients with type 2 diabetes: a systematic review and meta-analysis.	Diabetes, obesity & metabolism 20120601
The detection of the urinary metabolites of 3-[(adamantan-1-yl)carbonyl]-1-pentylindole (AB-001), a novel cannabimimetic, by gas chromatography-mass spectrometry.	Drug testing and analysis 20120601
Effectiveness of synthetic trioxolane OZ78 against Schistosoma japonicum in mice and rabbits.	Parasitology research 20120601
Combination therapy with metformin plus vildagliptin in type 2 diabetes mellitus.	Expert opinion on pharmacotherapy 20120601
Attenuation of cisplatin-induced renal injury by inhibition of soluble epoxide hydrolase involves nuclear factor κB signaling.	The Journal of pharmacology and experimental therapeutics 20120601
Vildagliptin added to metformin on β-cell function after a euglycemic hyperinsulinemic and hyperglycemic clamp in type 2 diabetes patients.	Diabetes technology & therapeutics 20120601
Cardiovascular protection of activating KATP channel during ischemia-reperfusion acidosis.	Shock (Augusta, Ga.) 20120601
Cucurbituril adamantanediazirine complexes and consequential carbene chemistry.	The Journal of organic chemistry 20120601
New adamantane derivatives can overcome resistance of influenza A(H1N1)pdm2009 and A(H3N2) viruses to remantadine.	Bulletin of experimental biology and medicine 20120601
Trapping of bulky guests inside dimeric molecular capsules formed by a deep-cavity cavitand.	The Journal of organic chemistry 20120518
Sterically congested adamantylnaphthalene quinone methides.	The Journal of organic chemistry 20120518
Synthesis, σ₁, σ₂-receptors binding affinity and antiproliferative action of new C1-substituted adamantanes.	Bioorganic & medicinal chemistry 20120515
Screening a library of 1600 adamantyl ureas for anti-Mycobacterium tuberculosis activity in vitro and for better physical chemical properties for bioavailability.	Bioorganic & medicinal chemistry 20120515
Infrared spectrum and structure of the adamantane cation: direct evidence for Jahn-Teller distortion.	Angewandte Chemie (International ed. in English) 20120514
A POSS-based supramolecular amphiphile and its hierarchical self-assembly behaviors.	Macromolecular rapid communications 20120514
Structure-dependent pseudoreceptor intracellular traffic of adamantyl globotriaosyl ceramide mimics.	The Journal of biological chemistry 20120511
Head-to-head prenyl tranferases: anti-infective drug targets.	Journal of medicinal chemistry 20120510
Electron paramagnetic resonance spectroscopic evidence for the interaction of HAlOH with water molecules.	The journal of physical chemistry. A 20120503
CD26/DPP-4 inhibition recruits regenerative stem cells via stromal cell-derived factor-1 and beneficially influences ischaemia-reperfusion injury in mouse lung transplantation.	European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20120501
SQ109 and PNU-100480 interact to kill Mycobacterium tuberculosis in vitro.	The Journal of antimicrobial chemotherapy 20120501
RF9 powerfully stimulates gonadotrophin secretion in the ewe: evidence for a seasonal threshold of sensitivity.	Journal of neuroendocrinology 20120501
An update in incretin-based therapy: a focus on dipeptidyl peptidase--4 inhibitors.	Current diabetes reviews 20120501
Stability-indicating RP-LC method for the determination of vildagliptin and mass spectrometry detection for a main degradation product.	Journal of chromatographic science 20120501
3-(Adamantan-1-yl)-4-ethyl-1H-1,2,4-triazole-5(4H)-thione.	Acta crystallographica. Section E, Structure reports online 20120501
2-{[5-(Adamantan-1-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfan-yl}-N,N-dimethyl-ethanamine.	Acta crystallographica. Section E, Structure reports online 20120501
3-(1-Adamant-yl)-4-amino-1-(2-benzoyl-1-phenyl-eth-yl)-1H-1,2,4-triazol-5(4H)-thione.	Acta crystallographica. Section E, Structure reports online 20120501
1-(Adamantan-1-yl)-3-(4-fluoro-phen-yl)thio-urea.	Acta crystallographica. Section E, Structure reports online 20120501
On-column ligand exchange for structure-based drug design: a case study with human 11β-hydroxysteroid dehydrogenase type 1.	Acta crystallographica. Section F, Structural biology and crystallization communications 20120501
Selective homogeneous and heterogeneous catalytic conversion of methanol/dimethyl ether to triptane.	Accounts of chemical research 20120417
Pyrazine-based Syk kinase inhibitors.	Bioorganic & medicinal chemistry letters 20120415
Relationships between the islets blood flow, nitric oxide, insulin, and cytosolic calcium in rat pancreatic islets: effects of DPP-IV inhibitor vildagliptin.	European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120411
Iron(II) complexes of new hexadentate 1,1,1-tris-(iminomethyl)ethane podands, and their 7-methyl-1,3,5-triazaadamantane rearrangement products.	Dalton transactions (Cambridge, England : 2003) 20120407
Construction of a graphene oxide based noncovalent multiple nanosupramolecular assembly as a scaffold for drug delivery.	Chemistry (Weinheim an der Bergstrasse, Germany) 20120402
The role of endogenous neurotensin in psychostimulant-induced disruption of prepulse inhibition and locomotion.	Schizophrenia research 20120401
Evaluation of antiproliferative effect of N-(alkyladamantyl)phthalimides in vitro.	Chemical biology & drug design 20120401
Adding saxagliptin to extended-release metformin vs. uptitrating metformin dosage.	Diabetes, obesity & metabolism 20120401
DPP-4 inhibitors in the management of type 2 diabetes: a critical review of head-to-head trials.	Diabetes & metabolism 20120401
Effect of saxagliptin as add-on therapy in patients with poorly controlled type 2 diabetes on insulin alone or insulin combined with metformin.	Current medical research and opinion 20120401
Dipeptidyl peptidase-4 inhibitors: 3 years of experience.	Diabetes technology & therapeutics 20120401
Highly sensitive colorimetric enzyme-linked oligonucleotide assay based on cyclodextrin-modified polymeric surfaces.	Analytical and bioanalytical chemistry 20120401
Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane.	Nature chemical biology 20120401
Synthesis and photodynamic properties of adamantylethoxy Zn(II) phthalocyanine derivatives in different media and in human red blood cells.	European journal of medicinal chemistry 20120401
Reply to: Ahren B et al. Mechanisms of action of the dipeptidyl peptidase-4 inhibitor vildagliptin in humans. Diabetes Obes Metab 2011; 13(9): 775-783 and Ahren B et al. Clinical evidence and mechanistic basis for vildagliptin's action when added to metformin. Diabetes Obes Metab 2011; 13(3): 193-203.	Diabetes, obesity & metabolism 20120401
Inhibition of vascular adenosine triphosphate-sensitive potassium channels by sympathetic tone during sepsis.	Critical care medicine 20120401
Effects of meal timing relative to dosing on the pharmacokinetics and pharmacodynamics of vildagliptin in Japanese patients with Type 2 diabetes.	International journal of clinical pharmacology and therapeutics 20120401
Synthesis and immunostimulating properties of novel adamant-1-yl tripeptides.	Chemistry & biodiversity 20120401
(E)-N-Benzyl-ideneadamantan-1-amine.	Acta crystallographica. Section E, Structure reports online 20120401
Bis(adamantan-1-aminium) carbonate.	Acta crystallographica. Section E, Structure reports online 20120401
3,5-Bis(adamantan-1-yl)-1-meth-oxy-benzene.	Acta crystallographica. Section E, Structure reports online 20120401
[Effects of ionotropic glutamate receptor channel blockers on the development of audiogenic seizures in Krushinski-Molodkina rats].	Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20120401
Enhanced asymmetric induction for the copolymerization of CO2 and cyclohexene oxide with unsymmetric enantiopure salenCo(III) complexes: synthesis of crystalline CO2-based polycarbonate.	Journal of the American Chemical Society 20120328
Generation of diamondoid hydrocarbons as confined compounds in SAPO-34 catalyst in the conversion of methanol.	Chemical communications (Cambridge, England) 20120325
Synthesis of uranium(VI) terminal oxo complexes: molecular geometry driven by the inverse trans-influence.	Journal of the American Chemical Society 20120321
Solution-phase synthesis of branched DNA hybrids based on dimer phosphoramidites and phenolic or nucleosidic cores.	The Journal of organic chemistry 20120316
Solution-phase synthesis of branched DNA hybrids via H-phosphonate dimers.	The Journal of organic chemistry 20120316
On the origin of siphonariid polypropionates: total synthesis of caloundrin B and its isomerization to siphonarin B.	Organic letters 20120316
Infectious diseases: Transporter targeted in tuberculosis.	Nature chemical biology 20120316
Activation of C-O and C-C bonds and formation of novel HAlOH-ether complexes: an EPR study of the reaction of ground-state Al atoms with methylethyl ether and diethyl ether.	The journal of physical chemistry. A 20120315
Liquid chromatography and tandem mass spectrometry method for the quantitative determination of saxagliptin and its major pharmacologically active 5-monohydroxy metabolite in human plasma: method validation and overcoming specific and non-specific binding at low concentrations.	Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120315
Polycyclic cage structures as lipophilic scaffolds for neuroactive drugs.	ChemMedChem 20120305
Pharmacokinetics and pharmacodynamics of AR9281, an inhibitor of soluble epoxide hydrolase, in single- and multiple-dose studies in healthy human subjects.	Journal of clinical pharmacology 20120301
Efficacy and safety of saxagliptin in drug-naïve Asian patients with type 2 diabetes mellitus: a randomized controlled trial.	Diabetes/metabolism research and reviews 20120301
Involvement of calcium-sensing receptor in oxLDL-induced MMP-2 production in vascular smooth muscle cells via PI3K/Akt pathway.	Molecular and cellular biochemistry 20120301
Characterization of COR627 and COR628, two novel positive allosteric modulators of the GABA(B) receptor.	The Journal of pharmacology and experimental therapeutics 20120301
Saxagliptin for the treatment of type 2 diabetes mellitus: focus on recent studies.	Annals of medicine 20120301
Soluble epoxide hydrolase inhibition improves myocardial perfusion and function in experimental heart failure.	Journal of molecular and cellular cardiology 20120301
Sphingosine kinase inhibition exerts both pro- and anti-atherogenic effects in low-density lipoprotein receptor-deficient (LDL-R(-/-)) mice.	Thrombosis and haemostasis 20120301
Reversed chloroquine molecules as a strategy to overcome resistance in malaria.	Current topics in medicinal chemistry 20120301
Cost effectiveness of saxagliptin and metformin versus sulfonylurea and metformin in the treatment of type 2 diabetes mellitus in Germany: a Cardiff diabetes model analysis.	Clinical drug investigation 20120301
Adamantyl N-benzylbenzamide: new series of depigmentation agents with tyrosinase inhibitory activity.	Bioorganic & medicinal chemistry letters 20120301
Saxagliptin plus metformin combination in patients with type 2 diabetes and renal impairment.	Expert opinion on drug metabolism & toxicology 20120301
Impact of the dipeptidyl peptidase-4 inhibitor vildagliptin on glucose tolerance and β-cell function and mass in insulin receptor substrate-2-knockout mice fed a high-fat diet.	Endocrinology 20120301
Clinical pharmacokinetics and pharmacodynamics of vildagliptin.	Clinical pharmacokinetics 20120301
3-(Adamantan-1-yl)-4-(prop-2-en-1-yl)-1H-1,2,4-triazole-5(4H)-thione.	Acta crystallographica. Section E, Structure reports online 20120301
3-(Adamantan-1-yl)-1-[(4-ethyl-piperazin-1-yl)meth-yl]-4-[(E)-(4-hy-droxy-benzyl-idene)amino]-1H-1,2,4-triazole-5(4H)-thione.	Acta crystallographica. Section E, Structure reports online 20120301
2-(Adamantan-1-yl)-5-(4-nitro-phen-yl)-1,3,4-oxadiazole.	Acta crystallographica. Section E, Structure reports online 20120301
Mechanism-based population modelling of the effects of vildagliptin on GLP-1, glucose and insulin in patients with type 2 diabetes.	British journal of clinical pharmacology 20120301
Mechanism-based population pharmacokinetic modelling in diabetes: vildagliptin as a tight binding inhibitor and substrate of dipeptidyl peptidase IV.	British journal of clinical pharmacology 20120301
2-Acylamino-6-pyridones: breaking of an intramolecular hydrogen bond by self-association and complexation with double and triple hydrogen bonding counterparts. Uncommon steric effect on intermolecular interactions.	The Journal of organic chemistry 20120217
Experimental and computational bridgehead C-H bond dissociation enthalpies.	The Journal of organic chemistry 20120217
Click modification in the N6 region of A3 adenosine receptor-selective carbocyclic nucleosides for dendrimeric tethering that preserves pharmacophore recognition.	Bioconjugate chemistry 20120215
Cyclodextrin polymer nanoassemblies: strategies for stability improvement.	Biomacromolecules 20120213
Supramolecular polymorphism of the 1:1 molecular salt (adamantane-1-carboxylate-3,5,7-tricarboxylic acid)·(hexamethylenetetraminium). A 'failed' crystal engineering attempt.	Chemical communications (Cambridge, England) 20120211
Intra- and intermolecular reaction selectivities of γ-substituted adamantanylidenes.	The Journal of organic chemistry 20120203
Stability and bioactivity studies on dipeptidyl peptidase IV resistant glucogan-like peptide-1 analogues.	Protein and peptide letters 20120201
Smart DNA vectors based on cyclodextrin polymers: compaction and endosomal release.	Pharmaceutical research 20120201
Post-conditioning protecting rat cardiomyocytes from apoptosis via attenuating calcium-sensing receptor-induced endo(sarco)plasmic reticulum stress.	Molecular and cellular biochemistry 20120201
Dipeptidyl peptidase IV inhibitor attenuates kidney injury in streptozotocin-induced diabetic rats.	The Journal of pharmacology and experimental therapeutics 20120201
Stimulation of Ca2+-sensing receptor inhibits the basolateral 50-pS K channels in the thick ascending limb of rat kidney.	Biochimica et biophysica acta 20120201
Role of p21 as a determinant of 1,6-Bis[4-(4-amino-3-hydroxyphenoxy)phenyl] diamantane response in human HCT-116 colon carcinoma cells.	Oncology reports 20120201
In vivo treatment of tumors using host-guest conjugated nanoparticles functionalized with doxorubicin and therapeutic gene pTRAIL.	Biomaterials 20120201
3-(Adamantan-1-yl)-4-phenyl-1-[(4-phenyl-piperazin-1-yl)meth-yl]-1H-1,2,4-triazole-5(4H)-thione.	Acta crystallographica. Section E, Structure reports online 20120201
Cytomimetic large-scale vesicle aggregation and fusion based on host-guest interaction.	Langmuir : the ACS journal of surfaces and colloids 20120131
Peroxisome proliferator-activated receptors (PPARs) have multiple binding points that accommodate ligands in various conformations: phenylpropanoic acid-type PPAR ligands bind to PPAR in different conformations, depending on the subtype.	Journal of medicinal chemistry 20120126
Saxagliptin: a review of its use as combination therapy in the management of type 2 diabetes mellitus in the EU.	Drugs 20120122
Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells.	Oncogene 20120119
Reaction mechanism in crystalline solids: kinetics and conformational dynamics of the Norrish type II biradicals from α-adamantyl-p-methoxyacetophenone.	Journal of the American Chemical Society 20120118
A novel long acting DPP-IV inhibitor PKF-275-055 stimulates β-cell proliferation resulting in improved glucose homeostasis in diabetic rats.	Biochemical pharmacology 20120115
Rotationally resolved infrared spectroscopy of adamantane.	The Journal of chemical physics 20120114
Responsive small molecular hydrogels based on adamantane-peptides for cell culture.	The journal of physical chemistry. B 20120112
Analogues of orphan nuclear receptor small heterodimer partner ligand and apoptosis inducer (E)-4-[3-(1-adamantyl)-4-hydroxyphenyl]-3-chlorocinnamic acid. 2. Impact of 3-chloro group replacement on inhibition of proliferation and induction of apoptosis of leukemia and cancer cell lines.	Journal of medicinal chemistry 20120112
Supramolecular host-guest interaction for labeling and detection of cellular biomarkers.	Angewandte Chemie (International ed. in English) 20120109
Planar chiral (η6-arene)Cr(CO)3 containing carboxylic acid derivatives: synthesis and use in the preparation of organometallic analogues of the antibiotic platensimycin.	Dalton transactions (Cambridge, England : 2003) 20120107
Activation of C-Cl by ground-state aluminum atoms: an EPR and DFT investigation.	Physical chemistry chemical physics : PCCP 20120107
Involvement of neuropeptide FF receptors in neuroadaptive responses to acute and chronic opiate treatments.	British journal of pharmacology 20120101
Sphingosine kinase-2 inhibition improves mitochondrial function and survival after hepatic ischemia-reperfusion.	Journal of hepatology 20120101
Treatment of genetically obese mice with the iminosugar N-(5-adamantane-1-yl-methoxy-pentyl)-deoxynojirimycin reduces body weight by decreasing food intake and increasing fat oxidation.	Metabolism: clinical and experimental 20120101
Cytotoxic properties of Adamantyl isothiocyanate and potential in vivo metabolite adamantyl-N-acetylcystein in gynecological cancer cells.	Chemical biology & drug design 20120101
Beneficial effects of PKF275-055, a novel, selective, orally bioavailable, long-acting dipeptidyl peptidase IV inhibitor in streptozotocin-induced diabetic peripheral neuropathy.	The Journal of pharmacology and experimental therapeutics 20120101
The cost-effectiveness of saxagliptin versus NPH insulin when used in combination with other oral antidiabetes agents in the treatment of type 2 diabetes mellitus in Poland.	Diabetes technology & therapeutics 20120101
Kisspeptin signaling is indispensable for neurokinin B, but not glutamate, stimulation of gonadotropin secretion in mice.	Endocrinology 20120101
Functional evidence for D-serine inhibition of non-N-methyl-D-aspartate ionotropic glutamate receptors in retinal neurons.	The European journal of neuroscience 20120101
Metformin + saxagliptin for type 2 diabetes.	Expert opinion on pharmacotherapy 20120101
Modulation of neuropeptide FF (NPFF) receptors influences the expression of amphetamine-induced conditioned place preference and amphetamine withdrawal anxiety-like behavior in rats.	Peptides 20120101
A pharmacometric approach to quantify the impact of chronic kidney disease and hemodialysis on systemic drug exposure: application to saxagliptin.	Journal of clinical pharmacology 20120101
Synthetic peroxides as potent antimalarials. News and views.	Current topics in medicinal chemistry 20120101
Saxagliptin for the treatment of type 2 diabetes mellitus: assessing cardiovascular data.	Cardiovascular diabetology 20120101
A new benzoylphloroglucinol derivative with an adamantyl skeleton and other constituents from Garcinia multiflora: effects on neutrophil pro-inflammatory responses.	Chemistry & biodiversity 20120101
A protocol for active surveillance of acute myocardial infarction in association with the use of a new antidiabetic pharmaceutical agent.	Pharmacoepidemiology and drug safety 20120101
Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy.	Theranostics 20120101
Rapid evaluation in whole blood culture of regimens for XDR-TB containing PNU-100480 (sutezolid), TMC207, PA-824, SQ109, and pyrazinamide.	PloS one 20120101
The anticipated severity of a '1918-like' influenza pandemic in contemporary populations: the contribution of antibacterial interventions.	PloS one 20120101
Use of Linear Free Energy Relationships (LFERs) to elucidate the mechanisms of reaction of a γ-methyl-β-alkynyl and an ortho-substituted aryl chloroformate ester.	International journal of molecular sciences 20120101
Adamantane-substituted guanylhydrazones: novel inhibitors of butyrylcholinesterase.	Bioorganic chemistry 20120101
Effect of the leaving group and solvent combination on the LFER reaction constants.	International journal of molecular sciences 20120101
Syntheses and in-vitro evaluation of novel adamantane based γ-secretase inhibitors.	Current medicinal chemistry 20120101
Monoclonal antibodies targeting the synthetic peptide corresponding to the polybasic cleavage site on H5N1 influenza hemagglutinin.	Journal of biomedical science 20120101
The synergistic effect of valsartan and LAF237 [(S)-1-[(3-hydroxy-1-adamantyl)ammo]acetyl-2-cyanopyrrolidine] on vascular oxidative stress and inflammation in type 2 diabetic mice.	Experimental diabetes research 20120101
Potency, selectivity and prolonged binding of saxagliptin to DPP4: maintenance of DPP4 inhibition by saxagliptin in vitro and ex vivo when compared to a rapidly-dissociating DPP4 inhibitor.	BMC pharmacology 20120101
Synthesis and antimicrobial studies of some novel bis-[1,3,4]thiadiazole and bis-thiazole pendant to thieno[2,3-b]thiophene moiety.	International journal of molecular sciences 20120101
Cyclodextrin-containing polymers: versatile platforms of drug delivery materials.	Journal of drug delivery 20120101
Challenges for accurate and prompt molecular diagnosis of clades of highly pathogenic avian influenza H5N1 viruses emerging in Vietnam.	Avian pathology : journal of the W.V.P.A 20120101
The fluorescence neuraminidase inhibition assay: a functional method for detection of influenza virus resistance to the neuraminidase inhibitors.	Methods in molecular biology (Clifton, N.J.) 20120101
Soluble epoxide hydrolase activity determines the severity of ischemia-reperfusion injury in kidney.	PloS one 20120101
Electrospray ionization mass spectrometry: a technique to access the information beyond the molecular weight of the analyte.	International journal of analytical chemistry 20120101
Vildagliptin selectively ameliorates GLP-1, GLUT4, SREBP-1c mRNA levels and stimulates β-cell proliferation resulting in improved glucose homeostasis in rats with streptozotocin-induced diabetes.	Journal of diabetes and its complications 20120101
Evidence to support the use of vildagliptin monotherapy in the treatment of type 2 diabetes mellitus.	Vascular health and risk management 20120101
Effects of a vildagliptin/metformin combination on markers of atherosclerosis, thrombosis, and inflammation in diabetic patients with coronary artery disease.	Cardiovascular diabetology 20120101
Cell number and transfection volume dependent peptide nucleic acid antisense activity by cationic delivery methods.	Artificial DNA, PNA & XNA 20120101
Long-lasting alterations in membrane properties, k(+) currents, and glutamatergic synaptic currents of nucleus accumbens medium spiny neurons in a rat model of alcohol dependence.	Frontiers in neuroscience 20120101
[Effect of ladasten on antenatal and postnatal development].	Eksperimental'naia i klinicheskaia farmakologiia 20120101
The atypical retinoid E-3-(3'-Adamantan-1-yl-4'-methoxybiphenyl-4-yl)-2-propenoic acid (ST1898) displays comedolytic activity in the rhino mouse model.	European journal of dermatology : EJD 20120101
Cost-effectiveness and budget impact of saxagliptine as additional therapy to metformin for the treatment of diabetes mellitus type 2 in the Brazilian private health system.	Revista da Associacao Medica Brasileira (1992) 20120101
Magic angle spinning solid-state NMR experiments for structural characterization of proteins.	Methods in molecular biology (Clifton, N.J.) 20120101
[Ladasten versus placebo effect self-evaluated by neurasthenia patients with different EEG alpha rhythm types].	Eksperimental'naia i klinicheskaia farmakologiia 20120101
Inhibition of sphingosine kinase-2 suppresses inflammation and attenuates graft injury after liver transplantation in rats.	PloS one 20120101
Comparison of vildagliptin twice daily vs. sitagliptin once daily using continuous glucose monitoring (CGM): crossover pilot study (J-VICTORIA study).	Cardiovascular diabetology 20120101
[Adamantane derivate enhances cerebral blood flow under conditions of ischemic brain damage].	Eksperimental'naia i klinicheskaia farmakologiia 20120101
Microfabricated inserts for magic angle coil spinning (MACS) wireless NMR spectroscopy.	PloS one 20120101
Cyclodextrin-based [1]rotaxanes on gold nanoparticles.	International journal of molecular sciences 20120101
Platensimycin and platencin biosynthesis in Streptomyces platensis, showcasing discovery and characterization of novel bacterial diterpene synthases.	Methods in enzymology 20120101
[Development of versatile oxidation systems based on the design of oxoammonium salts].	Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20120101
Attenuation of renovascular damage in Zucker diabetic fatty rat by NWT-03, an egg protein hydrolysate with ACE- and DPP4-inhibitory Activity.	PloS one 20120101
Pancreatitis with pancreatic tail swelling associated with incretin-based therapies detected radiologically in two cases of diabetic patients with end-stage renal disease.	Internal medicine (Tokyo, Japan) 20120101
Speedy and clean hypervalent iodine/nitroxyl radical mediated oxidation of alcohols using recyclable adamantane reagent with highly active 2-azaadamantane-N-oxyl organocatalyst.	Chemical & pharmaceutical bulletin 20120101
Amphiphilic star-block copolymers and supramolecular transformation of nanogel-like micelles to nanovesicles.	Chemical communications (Cambridge, England) 20111228
Nonequilibrium Fermi golden rule for electronic transitions through conical intersections.	The Journal of chemical physics 20111221
Kinetic and mechanistic insight into the thermodynamic degradation of saxagliptin.	The Journal of organic chemistry 20111216
Huge dielectric response and molecular motions in paddle-wheel [Cu(II)2(adamantylcarboxylate)4(DMF)2]⋅(DMF)2.	Chemistry (Weinheim an der Bergstrasse, Germany) 20111216
Adamantane-platinum conjugate hosted in β-cyclodextrin: enhancing transport and cytotoxicity by noncovalent modification.	Bioorganic & medicinal chemistry letters 20111215
Investigating the antimalarial action of 1,2,4-trioxolanes with fluorescent chemical probes.	Journal of medicinal chemistry 20111208
Thermoresponsive supramolecular dendronized polymers.	Chemistry, an Asian journal 20111202
Combined anticancer effects of sphingosine kinase inhibitors and sorafenib.	Investigational new drugs 20111201
Long-term treatment with the dipeptidyl peptidase-4 inhibitor saxagliptin in patients with type 2 diabetes mellitus and renal impairment: a randomised controlled 52-week efficacy and safety study.	International journal of clinical practice 20111201
Design, synthesis and in vitro evaluation of bridgehead fluoromethyl analogs of N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-N-(pyridin-2-yl)cyclohexanecarboxamide (WAY-100635) for the 5-HT(1A) receptor.	European journal of medicinal chemistry 20111201
Sterically congested quinone methides in photodehydration reactions of 4-hydroxybiphenyl derivatives and investigation of their antiproliferative activity.	Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20111201
(1-Adamant-yl)(3-amino-phen-yl)methanone.	Acta crystallographica. Section E, Structure reports online 20111201
[Incretin-based therapy for treating patients with type 2 diabetes].	Orvosi hetilap 20111127
Oxidative Prins-pinacol tandem process mediated by a hypervalent iodine reagent: scope, limitations, and applications.	The Journal of organic chemistry 20111118
Photochemical generation and reactivity of carbenes within an organic cavitand and capsule: photochemistry of adamantanediazirines.	Organic letters 20111118
Simultaneous interactions of anions and cations with cyclohexane and adamantane: aliphatic cyclic hydrocarbons as charge insulators.	The journal of physical chemistry. A 20111117
Design, synthesis, and SAR studies of novel polycyclic acids as potent and selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1).	Bioorganic & medicinal chemistry letters 20111115
Multiplexing interactions to control antibiotic release from cyclodextrin hydrogels.	Macromolecular bioscience 20111110
Structural investigation of rimantadine inhibition of the AM2-BM2 chimera channel of influenza viruses.	Structure (London, England : 1993) 20111109
Highly active ethylene polymerization and regioselective 1-hexene oligomerization using zirconium and titanium catalysts with tridentate [ONO] ligands.	Inorganic chemistry 20111107
Synthesis, antimicrobial and antiproliferative activity of novel silver(I) tris(pyrazolyl)methanesulfonate and 1,3,5-triaza-7-phosphadamantane complexes.	Inorganic chemistry 20111107
Synthesis and electronic structure determination of N-alkyl-substituted bis(imino)pyridine iron imides exhibiting spin crossover behavior.	Journal of the American Chemical Society 20111102
Selective inhibition of striatal fast-spiking interneurons causes dyskinesias.	The Journal of neuroscience : the official journal of the Society for Neuroscience 20111102
Adaphostin promotes caffeine-evoked autocrine Fas-mediated death pathway activation in Bcr/Abl-positive leukaemia cells.	The Biochemical journal 20111101
Inhibition of epoxy-eicosanoid degradation improves the tocolytic effects of indomethacin in the uterus from pregnant women.	Prostaglandins & other lipid mediators 20111101
Naja nigricollis CMS-9 enhances the mitochondria-mediated death pathway in adaphostin-treated human leukaemia U937 cells.	Clinical and experimental pharmacology & physiology 20111101
Target-mediated metabolism and target-mediated drug disposition of the DPPIV inhibitor AMG 222.	Xenobiotica; the fate of foreign compounds in biological systems 20111101
Efficacy and safety of saxagliptin added to metformin in Asian people with type 2 diabetes mellitus: a randomized controlled trial.	Diabetes research and clinical practice 20111101
Platensimycin and platencin: promising antibiotics for future application in human medicine.	The Journal of antibiotics 20111101
Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents.	Bioorganic & medicinal chemistry 20111101
In vivo transfection using cyclodextrin-containing polycations.	Cold Spring Harbor protocols 20111101
The design and rationale of the saxagliptin assessment of vascular outcomes recorded in patients with diabetes mellitus-thrombolysis in myocardial infarction (SAVOR-TIMI) 53 study.	American heart journal 20111101
1-(1-Adamantylmeth-yl)-1H-benzimidazole.	Acta crystallographica. Section E, Structure reports online 20111101
N'-(Adamantan-2-yl-idene)thio-phene-2-carbohydrazide.	Acta crystallographica. Section E, Structure reports online 20111101
Prospective of Genomics in Revealing Transmission, Reassortment and Evolution of Wildlife-Borne Avian Influenza A (H5N1) Viruses.	Current genomics 20111101
Emerging role of DPP-4 inhibitor Vildagliptin in the management of type-2 diabetes.	The Journal of the Association of Physicians of India 20111101
NMR study of ligand exchange and electron self-exchange between oxo-centered trinuclear clusters [Fe3(μ3-O)(μ-O2CR)6(4-R'py)3](+/0).	Inorganic chemistry 20111017
Nickel(II) complexes of tripodal 4N ligands as catalysts for alkane oxidation using m-CPBA as oxidant: ligand stereoelectronic effects on catalysis.	Dalton transactions (Cambridge, England : 2003) 20111007
Mono- and dinuclear iron complexes of bis(1-methylimidazol-2-yl)ketone (bik): structure, magnetic properties, and catalytic oxidation studies.	Inorganic chemistry 20111003
Safety and efficacy of vildagliptin versus placebo in patients with type 2 diabetes and moderate or severe renal impairment: a prospective 24-week randomized placebo-controlled trial.	Diabetes, obesity & metabolism 20111001
Impact of down-regulation of starch branching enzyme IIb in rice by artificial microRNA- and hairpin RNA-mediated RNA silencing.	Journal of experimental botany 20111001
Recognition properties of cucurbit[7]uril self-assembled monolayers studied with force spectroscopy.	Langmuir : the ACS journal of surfaces and colloids 20110920
N-Arylalkyl-2-azaadamantanes as cage-expanded polycarbocyclic sigma (σ) receptor ligands.	Bioorganic & medicinal chemistry letters 20110915
Identification of SQ609 as a lead compound from a library of dipiperidines.	Bioorganic & medicinal chemistry letters 20110915
Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection.	Nature 20110915
Synthesis and SAR requirements of adamantane-colchicine conjugates with both microtubule depolymerizing and tubulin clustering activities.	Bioorganic & medicinal chemistry 20110915
[Dipeptidyl-peptidase-4 inhibitors (gliptins): a new class of oral antidiabetic drugs].	Orvosi hetilap 20110911
Size-controlled nanoassemblies based on cyclodextrin-modified dextrans.	Macromolecular bioscience 20110909
1-Deoxy-D-galactonojirimycins with dansyl capped N-substituents as β-galactosidase inhibitors and potential probes for GM1 gangliosidosis affected cell lines.	Carbohydrate research 20110906
Adamantyl ethanone pyridyl derivatives: potent and selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1.	ChemMedChem 20110905
Mechanisms of action of the dipeptidyl peptidase-4 inhibitor vildagliptin in humans.	Diabetes, obesity & metabolism 20110901
Effects of saxagliptin on β-cell stimulation and insulin secretion in patients with type 2 diabetes.	Diabetes, obesity & metabolism 20110901
The metabolic syndrome influences the response to incretin-based therapies.	Acta diabetologica 20110901
Experimental studies and modeling of drug release from a tunable affinity-based drug delivery platform.	Annals of biomedical engineering 20110901
Efficacy of saxagliptin as an add-on to oral monotherapy in the phase 3 clinical development program: predictive factors of the treatment response in type 2 diabetes.	Annales d'endocrinologie 20110901
Vildagliptin improves endothelium-dependent vasodilatation in type 2 diabetes.	Diabetes care 20110901
Platensimycin and its relatives: a recent story in the struggle to develop new naturally derived antibiotics.	Natural product reports 20110901
[Influenza : clinical symptoms, diagnostics and therapy].	Der Internist 20110901
Multidrug resistant 2009 A/H1N1 influenza clinical isolate with a neuraminidase I223R mutation retains its virulence and transmissibility in ferrets.	PLoS pathogens 20110901
rac-2-{[1-(1-Adamant-yl)eth-yl]imino-meth-yl}-5-meth-oxy-phenol.	Acta crystallographica. Section E, Structure reports online 20110901
2-(1-Adamant-yl)-1-(3-amino-phen-yl)ethanol.	Acta crystallographica. Section E, Structure reports online 20110901
Thermodynamic properties of adamantane revisited.	The journal of physical chemistry. B 20110825
Synthesis and characterization of three-coordinate Ni(III)-imide complexes.	Journal of the American Chemical Society 20110824
HYDRAmers: design, synthesis and characterization of different generation novel Hydra-like dendrons based on multifunctionalized adamantane.	Chemical communications (Cambridge, England) 20110821
Cyclodextrin and adamantane host-guest interactions of modified hyperbranched poly(ethylene imine) as mimetics for biological membranes.	Angewandte Chemie (International ed. in English) 20110816
Investigations on the 4-quinolone-3-carboxylic acid motif. 4. Identification of new potent and selective ligands for the cannabinoid type 2 receptor with diverse substitution patterns and antihyperalgesic effects in mice.	Journal of medicinal chemistry 20110811
Ordered phases of encapsulated diamondoids into carbon nanotubes.	Nanotechnology 20110805
Ongoing clinical trials evaluating the cardiovascular safety and efficacy of therapeutic approaches to diabetes mellitus.	The American journal of cardiology 20110802
11β-hydroxysteroid dehydrogenases and the brain: from zero to hero, a decade of progress.	Frontiers in neuroendocrinology 20110801
Beta cell function following 1 year vildagliptin or placebo treatment and after 12 week washout in drug-naive patients with type 2 diabetes and mild hyperglycaemia: a randomised controlled trial.	Diabetologia 20110801
Dipeptidyl peptidase-4 inhibition increases portal concentrations of intact glucagon-like peptide-1 (GLP-1) to a greater extent than peripheral concentrations in anaesthetised pigs.	Diabetologia 20110801
Discovery of adamantyl heterocyclic ketones as potent 11β-hydroxysteroid dehydrogenase type 1 inhibitors.	ChemMedChem 20110801
Could LogP be a principal determinant of biological activity in 18-crown-6 ethers? Synthesis of biologically active adamantane-substituted diaza-crowns.	European journal of medicinal chemistry 20110801
Vildagliptin in the treatment of type 2 diabetes mellitus.	Expert opinion on pharmacotherapy 20110801
Small-molecule hydrophobic tagging-induced degradation of HaloTag fusion proteins.	Nature chemical biology 20110801
Saxagliptin: a clinical review in the treatment of type 2 diabetes mellitus.	Clinical therapeutics 20110801
New synthesis of 6[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid and evaluation of the influence of adamantyl group on the DNA binding of a naphthoic retinoid.	Bioorganic chemistry 20110801
Place in therapy for liraglutide and saxagliptin for type 2 diabetes and FDA liraglutide warning.	Southern medical journal 20110801
N-(2-Hy-droxy-benz-yl)adamantan-1-aminium bromide.	Acta crystallographica. Section E, Structure reports online 20110801
Novel lipophilic acetohydroxamic acid derivatives based on conformationally constrained spiro carbocyclic 2,6-diketopiperazine scaffolds with potent trypanocidal activity.	Journal of medicinal chemistry 20110728
A biomimetic principle for the chemical modification of metal surfaces: synthesis of tripodal catecholates as analogues of siderophores and mussel adhesion proteins.	Chemistry (Weinheim an der Bergstrasse, Germany) 20110725
The Suzuki reaction in aqueous media promoted by P, N ligands.	Molecules (Basel, Switzerland) 20110725
Amperometric detection of antibodies in serum: performance of self-assembled cyclodextrin/cellulose polymer interfaces as antigen carriers.	Organic & biomolecular chemistry 20110707
Saxagliptin, a potent, selective inhibitor of DPP-4, does not alter the pharmacokinetics of three oral antidiabetic drugs (metformin, glyburide or pioglitazone) in healthy subjects.	Diabetes, obesity & metabolism 20110701
Resistance mutations define specific antiviral effects for inhibitors of the hepatitis C virus p7 ion channel.	Hepatology (Baltimore, Md.) 20110701
Ligand-dependent regulation of the activity of the orphan nuclear receptor, small heterodimer partner (SHP), in the repression of bile acid biosynthetic CYP7A1 and CYP8B1 genes.	Molecular endocrinology (Baltimore, Md.) 20110701
Comparison of the dipeptidyl peptidase-4 inhibitor vildagliptin and the sulphonylurea gliclazide in combination with metformin, in Muslim patients with type 2 diabetes mellitus fasting during Ramadan: results of the VECTOR study.	Current medical research and opinion 20110701
Thorough QT study of the effects of vildagliptin, a dipeptidyl peptidase IV inhibitor, on cardiac repolarization and conduction in healthy volunteers.	Current medical research and opinion 20110701
Effect of rifampicin on the pharmacokinetics and pharmacodynamics of saxagliptin, a dipeptidyl peptidase-4 inhibitor, in healthy subjects.	British journal of clinical pharmacology 20110701
Synthesis and evaluation of fluorescent heterocyclic aminoadamantanes as multifunctional neuroprotective agents.	Bioorganic & medicinal chemistry 20110701
Efficacy and safety of saxagliptin combination therapy in US patients with type 2 diabetes.	Postgraduate medicine 20110701
1-(Bromo-meth-yl)adamantane.	Acta crystallographica. Section E, Structure reports online 20110701
What happens to hydrophobic interactions during transfer from the solution to the gas phase? The case of electrospray-based soft ionization methods.	Journal of the American Society for Mass Spectrometry 20110701
How do aminoadamantanes block the influenza M2 channel, and how does resistance develop?	Journal of the American Chemical Society 20110629
Selectivity and mechanism of hydrogen atom transfer by an isolable imidoiron(III) complex.	Journal of the American Chemical Society 20110629
Probing multivalent host-guest interactions between modified polymer layers by direct force measurement.	The journal of physical chemistry. B 20110623
Adamantyl glycosphingolipids provide a new approach to the selective regulation of cellular glycosphingolipid metabolism.	The Journal of biological chemistry 20110617
Heteroatom-substituted analogues of orphan nuclear receptor small heterodimer partner ligand and apoptosis inducer (E)-4-[3-(1-Adamantyl)-4-hydroxyphenyl]-3-chlorocinnamic acid.	Journal of medicinal chemistry 20110609
An adamantane-based building block for DNA networks.	Chemistry, an Asian journal 20110606
Saxagliptin improves glycaemic control and is well tolerated in patients with type 2 diabetes mellitus and renal impairment.	Diabetes, obesity & metabolism 20110601
Initial combination therapy with saxagliptin and metformin provides sustained glycaemic control and is well tolerated for up to 76 weeks.	Diabetes, obesity & metabolism 20110601
The many faces of the adamantyl group in drug design.	European journal of medicinal chemistry 20110601
Adamantanes as spherical nanosondes in adducts with a chiral dirhodium complex-discriminating enantiomers and probing spatial proximities.	Magnetic resonance in chemistry : MRC 20110601
CXCR3 antagonists: quaternary ammonium salts equipped with biphenyl- and polycycloaliphatic-anchors.	Bioorganic & medicinal chemistry 20110601
Adamantane-1-ammonium acetate.	Acta crystallographica. Section E, Structure reports online 20110601
N-(Adamantan-1-yl)-2-chloro-acetamide.	Acta crystallographica. Section E, Structure reports online 20110601
Effectiveness of adding vildagliptin to the treatment of diabetic patients nonresponsive to the combination of metformin and a sulphonylurea.	Arquivos brasileiros de endocrinologia e metabologia 20110601
Place in therapy for liraglutide and saxagliptin for type 2 diabetes.	Southern medical journal 20110601
Recent diabetes issues affecting the primary care clinician.	Southern medical journal 20110601
Design, synthesis, radiolabeling, and in vitro and in vivo evaluation of bridgehead iodinated analogues of N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-N-(pyridin-2-yl)cyclohexanecarboxamide (WAY-100635) as potential SPECT ligands for the 5-HT1A receptor.	Journal of medicinal chemistry 20110526
Protein-binding molecular switches via host-guest stabilized DNA hairpins.	Journal of the American Chemical Society 20110525
Cationic supramolecular nanoparticles for co-delivery of gene and anticancer drug.	Chemical communications (Cambridge, England) 20110521
A supramolecular approach to the preparation of charge-tunable dendritic polycations for efficient gene delivery.	Chemical communications (Cambridge, England) 20110521
A versatile Fréchet-dendron compound unifies host-guest and templated heterogeneous self-assembly.	Advanced materials (Deerfield Beach, Fla.) 20110517
Identification of individual tetra- and pentacyclic naphthenic acids in oil sands process water by comprehensive two-dimensional gas chromatography/mass spectrometry.	Rapid communications in mass spectrometry : RCM 20110515
Synthesis and evaluation of carbaborane derivatives of indomethacin as cyclooxygenase inhibitors.	Bioorganic & medicinal chemistry 20110515
Regioselective bis-functionalization of endohedral dimetallofullerene, La2@C80: extremal La-La distance.	Journal of the American Chemical Society 20110511
Solid-State NMR characterization of autofluorescent fibrils formed by the elastin-derived peptide GVGVAGVG.	Biomacromolecules 20110509
Highly substituted oxabicyclic derivatives from furan: synthesis of (±)-platensimycin.	Organic letters 20110506
Enzymatic preparation of 5-hydroxy-L-proline, N-Cbz-5-hydroxy-L-proline, and N-Boc-5-hydroxy-L-proline from (α-N-protected)-L-ornithine using a transaminase or an amine oxidase.	Enzyme and microbial technology 20110506
Highly efficient, organocatalytic aerobic alcohol oxidation.	Journal of the American Chemical Society 20110504
An analysis of the impact of FDA's guidelines for addressing cardiovascular risk of drugs for type 2 diabetes on clinical development.	Contemporary clinical trials 20110501
Vildagliptin blocks vascular injury in thoracic aorta of diabetic rats by suppressing advanced glycation end product-receptor axis.	Pharmacological research 20110501
DPP-4 inhibitors: impact on glycemic control and cardiovascular risk factors.	Diabetes care 20110501
Interfacial tension of the lipid membrane formed from phosphatidylcholine-decanoic acid and phosphatidylcholine-decylamine systems.	The Journal of membrane biology 20110501
[Vildagliptin].	Nihon rinsho. Japanese journal of clinical medicine 20110501
Highly regioselective amination of unactivated alkanes by hypervalent sulfonylimino-λ³-bromane.	Science (New York, N.Y.) 20110422
Catalytic C-H bond amination from high-spin iron imido complexes.	Journal of the American Chemical Society 20110406
Inhibitory effect of N-adamantyl-3,4-dihydroxybenzamide on melanogenesis in melan-a cells and brown guinea pigs.	Archives of dermatological research 20110401
Attenuation of arthritis in rodents by a novel orally-available inhibitor of sphingosine kinase.	Inflammopharmacology 20110401
Neuropeptide FF receptor antagonist, RF9, attenuates the fever induced by central injection of LPS in mice.	Peptides 20110401
Inhibition of DPP-4 with vildagliptin improved insulin secretion in response to oral as well as 'isoglycemic' intravenous glucose without numerically changing the incretin effect in patients with type 2 diabetes.	The Journal of clinical endocrinology and metabolism 20110401
Soluble epoxide hydrolase in the generation and maintenance of high blood pressure in spontaneously hypertensive rats.	American journal of physiology. Endocrinology and metabolism 20110401
Adamantanyl-histone deacetylase inhibitor H6CAHA exhibits favorable pharmacokinetics and augments prostate cancer radiation sensitivity.	International journal of radiation oncology, biology, physics 20110401
Targeting NFĸB mediated breast cancer chemoresistance through selective inhibition of sphingosine kinase-2.	Cancer biology & therapy 20110401
Activity of OZ78 analogues against Fasciola hepatica and Echinostoma caproni.	Acta tropica 20110401
Efficacy and safety of saxagliptin in older patients with type 2 diabetes mellitus.	Current medical research and opinion 20110401
Influence of renal or hepatic impairment on the pharmacokinetics of saxagliptin.	Clinical pharmacokinetics 20110401
FDA's first active medical product surveillance eyes antidiabetic-MI link.	American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110401
Multivalent interactions: a hop, skip and jump.	Nature chemistry 20110401
Gradient-driven motion of multivalent ligand molecules along a surface functionalized with multiple receptors.	Nature chemistry 20110401
Dihydrogen contacts in alkanes are subtle but not faint.	Nature chemistry 20110401
Understanding the incretin effect.	The Journal of clinical endocrinology and metabolism 20110401
Safety and efficacy of saxagliptin added to thiazolidinedione over 76 weeks in patients with type 2 diabetes mellitus.	Diabetes & vascular disease research 20110401
Safety and efficacy of saxagliptin in combination with submaximal sulphonylurea versus up-titrated sulphonylurea over 76 weeks.	Diabetes & vascular disease research 20110401
6-(1-Adamant-yl)-3-(2-chloro-phen-yl)-1,2,4-triazolo[3,4-b][1,3,4]thia-diazole.	Acta crystallographica. Section E, Structure reports online 20110401
(2SR,3RS)-Methyl 2-(adamantan-1-yl)-3-phenyl-sulfonyl-3-(pyridin-2-ylsulfan-yl)propano-ate dichloro-methane hemisolvate.	Acta crystallographica. Section E, Structure reports online 20110401
Emerging role of dipeptidyl peptidase-IV (DPP-4) inhibitor vildagliptin in the management of type 2 diabetes.	The Journal of the Association of Physicians of India 20110401
Specific binding of adamantane drugs and direction of their polar amines in the pore of the influenza M2 transmembrane domain in lipid bilayers and dodecylphosphocholine micelles determined by NMR spectroscopy.	Journal of the American Chemical Society 20110330
Photogenerated cumulenic structure of adamantyl endcapped linear carbon chains: an experimental and computational investigation based on infrared spectroscopy.	The Journal of chemical physics 20110328
Platensimycin and platencin congeners from Streptomyces platensis.	Journal of natural products 20110325
Dipeptidyl peptidase IV dependent water-soluble prodrugs of highly lipophilic bicyclic nucleoside analogues.	Journal of medicinal chemistry 20110324
Structure-activity relationships of cycloalkylamide derivatives as inhibitors of the soluble epoxide hydrolase.	Journal of medicinal chemistry 20110324
Why benchmark-quality computations are needed to reproduce 1-adamantyl cation NMR chemical shifts accurately.	The journal of physical chemistry. A 20110324
Saxagliptin/metformin (kombiglyze XR) for type 2 diabetes.	The Medical letter on drugs and therapeutics 20110321
New ultrahigh affinity host-guest complexes of cucurbit[7]uril with bicyclo[2.2.2]octane and adamantane guests: thermodynamic analysis and evaluation of M2 affinity calculations.	Journal of the American Chemical Society 20110316
Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria.	Proceedings of the National Academy of Sciences of the United States of America 20110315
Dialkylamino-2,4-dihydroxybenzoic acids as easily synthesized analogues of platensimycin and platencin with comparable antibacterial properties.	Chemistry (Weinheim an der Bergstrasse, Germany) 20110314
Discovery of novel and potent orally active calcium-sensing receptor antagonists that stimulate pulselike parathyroid hormone secretion: synthesis and structure-activity relationships of tetrahydropyrazolopyrimidine derivatives.	Journal of medicinal chemistry 20110310
Semi-metallic single-component crystal of soluble La@C82 derivative with high electron mobility.	Journal of the American Chemical Society 20110302
Synthesis, structures and in vitro cytotoxicity of some cationic cis-platinum(II) complexes containing chelating thiocarbamates.	Journal of inorganic biochemistry 20110301
Current approaches to exploit actinomycetes as a source of novel natural products.	Journal of industrial microbiology & biotechnology 20110301
A small MRI contrast agent library of gadolinium(III)-encapsulated supramolecular nanoparticles for improved relaxivity and sensitivity.	Biomaterials 20110301
Inhibition of soluble epoxide hydrolase attenuates endothelial dysfunction in animal models of diabetes, obesity and hypertension.	European journal of pharmacology 20110301
Clinical evidence and mechanistic basis for vildagliptin's action when added to metformin.	Diabetes, obesity & metabolism 20110301
Synthesis and antiviral evaluation of bisnoradamantane sulfites and related compounds.	Medicinal chemistry (Shariqah (United Arab Emirates)) 20110301
Antitumor activity of sphingosine kinase 2 inhibitor ABC294640 and sorafenib in hepatocellular carcinoma xenografts.	Cancer biology & therapy 20110301
Adamantan-1-aminium p-toluene-sulfonate.	Acta crystallographica. Section E, Structure reports online 20110301
Time course of histone deacetylase 1 and acetylated H3 and H4 histones in the brain of rats treated with ladasten.	Bulletin of experimental biology and medicine 20110301
Synthesis of 1,8-di(1-adamantyl)naphthalenes as single enantiomers stable at ambient temperatures.	Chemical communications (Cambridge, England) 20110207
Water-soluble Cp ruthenium complex containing 1,3,5-triaza-7-phosphaadamantane and 8-thiotheophylline derivatives: synthesis, characterization, and antiproliferative activity.	Inorganic chemistry 20110207
Computational study of drug binding to the membrane-bound tetrameric M2 peptide bundle from influenza A virus.	Biochimica et biophysica acta 20110201
Resistance characteristics of influenza to amino-adamantyls.	Biochimica et biophysica acta 20110201
Inhibition of recombinant N-type and native high voltage-gated neuronal Ca2+ channels by AdGABA: mechanism of action studies.	Toxicology and applied pharmacology 20110201
1-(1-acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia.	Bioorganic & medicinal chemistry letters 20110201
New avian influenza virus (H5N1) in wild birds, Qinghai, China.	Emerging infectious diseases 20110201
Oseltamivir-resistant pandemic (H1N1) 2009 virus, Mexico.	Emerging infectious diseases 20110201
Prevalence of epistasis in the evolution of influenza A surface proteins.	PLoS genetics 20110201
[Adamantane resistance among seasonal influenza A viruses between January to October in Guangzhou, 2009].	Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20110201
Conformationally restricted GABA analogs: from rigid carbocycles to cage hydrocarbons.	Future medicinal chemistry 20110201
Incretin therapies in the management of elderly patients with type 2 diabetes mellitus.	Hospital practice (1995) 20110201
Saxagliptin. No more effective than other gliptins, but a high potential for drug interactions.	Prescrire international 20110201
1,3,5,7-Tetra-bromo-adamantane.	Acta crystallographica. Section E, Structure reports online 20110201
The DPP-4 inhibitor vildagliptin increases pancreatic beta cell mass in neonatal rats.	European journal of pharmacology 20110115
The dipeptidyl peptidase IV (CD26, EC 3.4.14.5) inhibitor vildagliptin is a potent antihyperalgesic in rats by promoting endomorphin-2 generation in the spinal cord.	European journal of pharmacology 20110110
Antiviral drugs for influenza.	The Medical letter on drugs and therapeutics 20110110
Tuning the conversion of cyclohexane into cyclohexanol/one by molecular dioxygen, protons and reducing agents at a single non-porphyrinic iron centre and chemical versatility of the tris(2-pyridylmethyl)amine TPAFe(II)Cl2 complex in mild oxidation chemistry.	Dalton transactions (Cambridge, England : 2003) 20110107
Supramolecular thermoresponsive hyperbranched polymers constructed from poly(N-isopropylacrylamide) containing one adamantyl and two β-cyclodextrin terminal moieties.	Macromolecular rapid communications 20110103
Maximal adamantyl-substituted retinoid-related molecule-induced apoptosis requires NF-κB noncanonical and canonical pathway activation.	Cell death and differentiation 20110101
Potential of Complementary and Alternative Medicine in Preventive Management of Novel H1N1 Flu (Swine Flu) Pandemic: Thwarting Potential Disasters in the Bud.	Evidence-based complementary and alternative medicine : eCAM 20110101
Structure-based and property-compliant library design of 11β-HSD1 adamantyl amide inhibitors.	Methods in molecular biology (Clifton, N.J.) 20110101
Discovery of a novel IKK-β inhibitor by ligand-based virtual screening techniques.	Bioorganic & medicinal chemistry letters 20110101
Synthesis and 11β hydroxysteroid dehydrogenase 1 inhibition of thiazolidine derivatives with an adamantyl group.	Bioorganic & medicinal chemistry letters 20110101
Clinical experience with vildagliptin in the management of type 2 diabetes in a patient population ≥75 years: a pooled analysis from a database of clinical trials.	Diabetes, obesity & metabolism 20110101
Molecular and structural determinants of adamantyl susceptibility to HLA-DRs allelic variants: an in silico approach to understand the mechanism of MLEs.	Journal of computer-aided molecular design 20110101
On the mechanisms of bananin activity against severe acute respiratory syndrome coronavirus.	The FEBS journal 20110101
Emerging influenza antiviral resistance threats.	The Journal of infectious diseases 20110101
Dual resistance to adamantanes and oseltamivir among seasonal influenza A(H1N1) viruses: 2008-2010.	The Journal of infectious diseases 20110101
Focus on incretin-based therapies: targeting the core defects of type 2 diabetes.	Postgraduate medicine 20110101
Anti-amnesic and neuroprotective actions of the sigma-1 receptor agonist (-)-MR22 in rats with selective cholinergic lesion and amyloid infusion.	Journal of Alzheimer's disease : JAD 20110101
Vildagliptin-induced acute pancreatitis.	Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20110101
Comments on the article 'Effects of vildagliptin twice daily vs. sitagliptin once daily on 24-hour acute glucose fluctuations' by Marfella et al.: (Journal of Diabetes and Its Complications 24 [2010] 79-83).	Journal of diabetes and its complications 20110101
Experimental osteoarthritis in rats is attenuated by ABC294640, a selective inhibitor of sphingosine kinase-2.	Pharmacology 20110101
Public health interventions for epidemics: implications for multiple infection waves.	BMC public health 20110101
Assessing the general safety and tolerability of vildagliptin: value of pooled analyses from a large safety database versus evaluation of individual studies.	Vascular health and risk management 20110101
Caffeoylquinic acids are major constituents with potent anti-influenza effects in brazilian green propolis water extract.	Evidence-based complementary and alternative medicine : eCAM 20110101
[Ladasten in the management of non-motor symptoms of Parkinson's disease].	Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101
[Plasmapheresis as treatment for severe hypertriglyceridemia].	Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20110101
[A comparative study of hemantane and amantadine effects on dopamine transporter expression in brain of normal and MPTP-treated C57BL/6 mice].	Eksperimental'naia i klinicheskaia farmakologiia 20110101
A novel disulfide-rich protein motif from avian eggshell membranes.	PloS one 20110101
Reassortment and mutations associated with emergence and spread of oseltamivir-resistant seasonal influenza A/H1N1 viruses in 2005-2009.	PloS one 20110101
In Vitro Gene Delivery Mediated by Asialofetuin-Appended Cationic Liposomes Associated with γ-Cyclodextrin into Hepatocytes.	Journal of drug delivery 20110101
4-[(1-Adamant-yl)carbamo-yl]pyridinium chloride.	Acta crystallographica. Section E, Structure reports online 20110101
Correlation of the rates of solvolysis of neopentyl chloroformate-a recommended protecting agent.	International journal of molecular sciences 20110101
Accelerated retinal ganglion cell death in mice deficient in the Sigma-1 receptor.	Molecular vision 20110101
[New adamantane derivatives and ways of overcoming the resistance of influenza A viruses to rimantadine and amantadine].	Voprosy virusologii 20110101
Fibrous architectures and organogels of tris(phenylethynylphenyl)adamantane molecules with amino acid moieties: their solvato-controlled helicity induction.	Chirality 20110101
Effect of enhanced glycemic control with saxagliptin on endothelial nitric oxide release and CD40 levels in obese rats.	Journal of atherosclerosis and thrombosis 20110101
Antidepressant potential of nitrogen-containing heterocyclic moieties: An updated review.	Journal of pharmacy & bioallied sciences 20110101
Incretin-based therapy and pancreatitis-what is the risk?	Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20110101
Genomic and protein structural maps of adaptive evolution of human influenza A virus to increased virulence in the mouse.	PloS one 20110101
New respiratory viruses and the elderly.	The open respiratory medicine journal 20110101
Reply to the 'Comments on the article 'Effects of vildagliptin twice daily vs. sitagliptin once daily on 24-hour acute glucose fluctuations'', by Avogaro (Journal of Diabetes and Its Complications 25 [2011] 352-353).	Journal of diabetes and its complications 20110101
[Influence of hemantane and doxycycline on MPTP-evoked behavior violations in C57BL/6 mice].	Eksperimental'naia i klinicheskaia farmakologiia 20110101
Bioequivalence of saxagliptin/metformin extended-release (XR) fixed-dose combination tablets and single-component saxagliptin and metformin XR tablets in healthy adult subjects.	Clinical drug investigation 20110101
Comparative efficacy of vildagliptin and sitagliptin in Japanese patients with type 2 diabetes mellitus: a matching-adjusted indirect comparison of randomized trials.	Clinical drug investigation 20110101
Rapid detection and subtyping of human influenza A viruses and reassortants by pyrosequencing.	PloS one 20110101
[Comparative study of amantadine and hemantane effects on development of levodopa-induced dyskinesia in rat model of parkinsonian syndrome].	Eksperimental'naia i klinicheskaia farmakologiia 20110101
Glycosphingolipids and insulin resistance.	Advances in experimental medicine and biology 20110101
Hyperbranched polyethylenimine bearing cyclodextrin moieties showing temperature and pH controlled dye release.	Beilstein journal of organic chemistry 20110101
The dipeptidyl peptidase-4 (DPP-4) inhibitor vildagliptin improves glycemic control in type 2 diabetic patients undergoing hemodialysis.	Endocrine journal 20110101
Assessment of the antiviral properties of recombinant porcine SP-D against various influenza A viruses in vitro.	PloS one 20110101
Solvolyses of benzoyl chlorides in weakly nucleophilic media.	International journal of molecular sciences 20110101
Early and late effects of the DPP-4 inhibitor vildagliptin in a rat model of post-myocardial infarction heart failure.	Cardiovascular diabetology 20110101
Calcium-permeable AMPA receptors in the retina.	Frontiers in molecular neuroscience 20110101
Molecular evolution of the H6 subtype influenza A viruses from poultry in eastern China from 2002 to 2010.	Virology journal 20110101
Effects of alkaline or liquid-ammonia treatment on crystalline cellulose: changes in crystalline structure and effects on enzymatic digestibility.	Biotechnology for biofuels 20110101
9-Azanoradamantane N-oxyl (Nor-AZADO): a highly active organocatalyst for alcohol oxidation.	Chemical & pharmaceutical bulletin 20110101
Molecular epidemiology of influenza A/H3N2 viruses circulating in Uganda.	PloS one 20110101
[Investigation of antiviral activity of adamantan boron derivaties on pandemic influenza virus models].	Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20110101
A supramolecular sensing platform for phosphate anions and an anthrax biomarker in a microfluidic device.	International journal of molecular sciences 20110101
Correlation of the rates of solvolysis of i-butyl fluoroformate and a consideration of leaving-group effects.	International journal of molecular sciences 20110101
[Analysis of the binding capacity of the benzodiazepine site of gabaa receptor in mice C57BL/6 and BALB/C pretreated with anxiolytics].	Eksperimental'naia i klinicheskaia farmakologiia 20110101
Influenza A(H1N1) Oseltamivir Resistant Viruses in the Netherlands During the Winter 2007/2008.	The open virology journal 20110101
[Effect of antiasthenic drug ladasten on the level of cytokines and behavior in experimental model of anxious depression in C57BL/6 male mice].	Eksperimental'naia i klinicheskaia farmakologiia 20110101
[Self-evaluation of single test doses and objective indices of ladasten vs. placebo efficacy in neurasthenic patients].	Eksperimental'naia i klinicheskaia farmakologiia 20110101
[Pharmacokinetics of hemantane in rats].	Eksperimental'naia i klinicheskaia farmakologiia 20110101
[Present and future in the use of anti-tubercular drugs].	Pneumologia (Bucharest, Romania) 20110101
[Characterization of patients with type 2 diabetes treated with vildagliptin].	Acta medica portuguesa 20110101
Schizophrenia: a pathogenetic autoimmune disease caused by viruses and pathogens and dependent on genes.	Journal of pathogens 20110101
Homoleptic diphosphacyclobutadiene complexes [M(η(4)-P2C2R2)2]x- (M = Fe, Co; x = 0, 1).	Chemistry (Weinheim an der Bergstrasse, Germany) 20101227
Concise formal total synthesis of platensimycin mediated by a stereoselective autoxidation and hydroxyl group directed conjugative reduction.	Organic letters 20101217
Pressure perturbation calorimetry and the thermodynamics of noncovalent interactions in water: comparison of protein-protein, protein-ligand, and cyclodextrin-adamantane complexes.	The journal of physical chemistry. B 20101216
Synthesis and structure-activity relationship of tetrahydropyrazolopyrimidine derivatives--a novel structural class of potent calcium-sensing receptor antagonists.	Bioorganic & medicinal chemistry 20101215

A phase 2a randomized, double-blind, placebo-controlled, sequential dose-escalation study to evaluate the efficacy and safety of ASP015K, a novel Janus kinase inhibitor, in patients with moderate-to-severe psoriasis.

The British journal of dermatology 20150901

Effects of bioisosteric fluorine in synthetic cannabinoid designer drugs JWH-018, AM-2201, UR-144, XLR-11, PB-22, 5F-PB-22, APICA, and STS-135.

ACS chemical neuroscience 20150819

Dysregulation of retinoic acid receptor diminishes hepatocyte permissiveness to hepatitis B virus infection through modulation of sodium taurocholate cotransporting polypeptide (NTCP) expression.

The Journal of biological chemistry 20150227

Saxagliptin: a novel antiparkinsonian approach.

Neuropharmacology 20150201

Pharmacological targeting of the pseudokinase Her3.

Nature chemical biology 20141201

Efficacy and safety evaluation of HSD-1 inhibitor ABT-384 in Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association 20141001

Peripheral and central nervous system inhibition of 11β-hydroxysteroid dehydrogenase type 1 in man by the novel inhibitor ABT-384.

Translational psychiatry 20130801

Effect of ketoconazole on the pharmacokinetics of the 11β-hydroxysteroid dehydrogenase type 1 inhibitor ABT-384 and its two active metabolites in healthy volunteers: population analysis of data from a drug-drug interaction study.

Drug metabolism and disposition: the biological fate of chemicals 20130501

Saxagliptin overview: special focus on safety and adverse effects.

Expert opinion on drug safety 20130101

Adenosine A2A receptor modulates vascular response in soluble epoxide hydrolase-null mice through CYP-epoxygenases and PPARγ.

American journal of physiology. Regulatory, integrative and comparative physiology 20130101

Exploiting adamantane as a versatile organic tecton: multicomponent catalytic cascade reactions.

Chemical communications (Cambridge, England) 20121207

A novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor, teneligliptin, improves postprandial hyperglycemia and dyslipidemia after single and repeated administrations.

European journal of pharmacology 20121205

Development of a rapid UPLC-MS/MS method for quantification of saxagliptin in rat plasma and application to pharmacokinetic study.

Biomedical chromatography : BMC 20121201

Shell cross-linking of cyclodextrin-based micelles via supramolecular chemistry for the delivery of drugs.

Macromolecular rapid communications 20121114

One-year safety, tolerability and efficacy of vildagliptin in patients with type 2 diabetes and moderate or severe renal impairment.

Diabetes, obesity & metabolism 20121101

Safety of saxagliptin: rationale for and design of a series of postmarketing observational studies.

Pharmacoepidemiology and drug safety 20121101

Adamantyl carboxamides and acetamides as potent human 11β-hydroxysteroid dehydrogenase type 1 inhibitors.

Bioorganic & medicinal chemistry 20121101

Identification of antischistosomal leads by evaluating bridged 1,2,4,5-tetraoxanes, alphaperoxides, and tricyclic monoperoxides.

Journal of medicinal chemistry 20121025

4-Oxo-1,4-dihydropyridines as selective CB₂ cannabinoid receptor ligands. Part 2: discovery of new agonists endowed with protective effect against experimental colitis.

Journal of medicinal chemistry 20121025

Synthesis and transformation of linear adamantane assemblies inside carbon nanotubes.

ACS nano 20121023

Synthesis, crystal structure and thermal properties of Ca6(C12H14O4)4(CO3)(OH)2(H2O)x--a 3D inorganic hybrid material.

Dalton transactions (Cambridge, England : 2003) 20121021

Stable silaimines with three- and four-coordinate silicon atoms.

Inorganic chemistry 20121015

The synthesis of W-O-W μ-oxo clusters by hydrolysis of tungsten aminoalkoxides and their structural characterisation.

Dalton transactions (Cambridge, England : 2003) 20121007

Eppendorf finalist. Striatal interneurons: causes of or cures for movement disorders?

Science (New York, N.Y.) 20121005

Quantitative model of the relationship between dipeptidyl peptidase-4 (DPP-4) inhibition and response: meta-analysis of alogliptin, saxagliptin, sitagliptin, and vildagliptin efficacy results.

Journal of clinical pharmacology 20121001

Effects of saxagliptin and sitagliptin on glycaemic control and pancreatic β-cell mass in a streptozotocin-induced mouse model of type 2 diabetes.

Diabetes, obesity & metabolism 20121001

Reduction of oxidative stress and inflammation by blunting daily acute glucose fluctuations in patients with type 2 diabetes: role of dipeptidyl peptidase-IV inhibition.

Diabetes care 20121001

Add-on therapies to metformin in type 2 diabetes: what modulates the respective decrements in postprandial and basal glucose?

Diabetes technology & therapeutics 20121001

Continuous glucose profiles with vildagliptin versus sitagliptin in add-on to metformin: results from the randomized Optima study.

Diabetes & metabolism 20121001

DPP4 inhibitor vildagliptin preserves β-cell mass through amelioration of endoplasmic reticulum stress in C/EBPB transgenic mice.

Journal of molecular endocrinology 20121001

Vildagliptin reduces glucagon during hyperglycemia and sustains glucagon counterregulation during hypoglycemia in type 1 diabetes.

The Journal of clinical endocrinology and metabolism 20121001

Pharmacological inhibition of soluble epoxide hydrolase provides cardioprotection in hyperglycemic rats.

American journal of physiology. Heart and circulatory physiology 20121001

Assembly of water-soluble, dynamic, covalent container molecules and their application in the room-temperature stabilization of protoadamantene.

Chemistry (Weinheim an der Bergstrasse, Germany) 20121001

Effects of saxagliptin added to sub-maximal doses of metformin compared with uptitration of metformin in type 2 diabetes: the PROMPT study.

Current medical research and opinion 20121001

Chronic DPP-IV inhibition with PKF-275-055 attenuates inflammation and improves gene expressions responsible for insulin secretion in streptozotocin induced diabetic rats.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120929

Exceptional chemical properties of Sc@C(2v)(9)-C82 probed with adamantylidene carbene.

Journal of the American Chemical Society 20120919

Anti-diabetic and anti-adipogenic effects of a novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor in the diet-induced obese mice.

European journal of pharmacology 20120915

Effects of long-term treatment with the dipeptidyl peptidase-4 inhibitor vildagliptin on islet endocrine cells in non-obese type 2 diabetic Goto-Kakizaki rats.

European journal of pharmacology 20120915

A supramolecular route towards core-shell polymeric microspheres in water via cucurbit[8]uril complexation.

Chemical communications (Cambridge, England) 20120911

Surface modified liposomes by mannosylated conjugates anchored via the adamantyl moiety in the lipid bilayer.

Biochimica et biophysica acta 20120901

Regioselective synthesis of 1,3,5-adamantanetriol from 1,3-adamantanediol using Kitasatospora cells.

Biotechnology letters 20120901

DPP4 inhibition improves functional outcome after renal ischemia-reperfusion injury.

American journal of physiology. Renal physiology 20120901

Dipeptidyl-peptidase-IV by cleaving neuropeptide Y induces lipid accumulation and PPAR-γ expression.

Peptides 20120901

H1N1 2009 pandemic influenza virus: resistance of the I223R neuraminidase mutant explained by kinetic and structural analysis.

PLoS pathogens 20120901

Calix[4]tubes: an approach to functionalization.

Chemistry (Weinheim an der Bergstrasse, Germany) 20120827

Effects of trehalose polycation end-group functionalization on plasmid DNA uptake and transfection.

Biomacromolecules 20120813

Ligand effects on hydrogen atom transfer from hydrocarbons to three-coordinate iron imides.

Inorganic chemistry 20120806

Enhanced cell cycle perturbation and apoptosis mediate the synergistic effects of ST1926 and ATRA in neuroblastoma preclinical models.

Investigational new drugs 20120801

The efficacy and safety of vildagliptin in patients with type 2 diabetes: a meta-analysis of randomized clinical trials.

Journal of clinical pharmacy and therapeutics 20120801

Efficacy and tolerability of vildagliptin as add-on therapy to metformin in Chinese patients with type 2 diabetes mellitus.

Diabetes, obesity & metabolism 20120801

Synthesis and antimicrobial evaluation of novel platensimycin analogues.

Archiv der Pharmazie 20120801

Depolarization potentiates TRAIL-induced apoptosis in human melanoma cells: role for ATP-sensitive K+ channels and endoplasmic reticulum stress.

International journal of oncology 20120801

Cardioprotective effects of metformin and vildagliptin in adult rats with insulin resistance induced by a high-fat diet.

Endocrinology 20120801

Novel polycyclic 'cage'-1,2-diamines as potential anti-tuberculosis agents.

European journal of medicinal chemistry 20120801

Uranium(III)-mediated C-C-coupling of terminal alkynes: formation of dinuclear uranium(IV) vinyl complexes.

Journal of the American Chemical Society 20120801

Ortho-carbaborane derivatives of indomethacin as cyclooxygenase (COX)-2 selective inhibitors.

Bioorganic & medicinal chemistry 20120801

5-(Adamantan-1-yl)-3-[(2-meth-oxy-eth-yl)sulfan-yl]-4-phenyl-4H-1,2,4-triazole.

Acta crystallographica. Section E, Structure reports online 20120801

3-(Adamantan-1-yl)-4-ethyl-1-[(4-phenyl-piperazin-1-yl)meth-yl]-1H-1,2,4-triazole-5(4H)-thione.

Acta crystallographica. Section E, Structure reports online 20120801

5-(Adamantan-1-yl)-3-(benzyl-sulfan-yl)-4-methyl-4H-1,2,4-triazole.

Acta crystallographica. Section E, Structure reports online 20120801

Overcoming bioanalytical challenges in an Onglyza(®) intravenous [(14)C]microdose absolute bioavailability study with accelerator MS.

Bioanalysis 20120801

Jahn-Teller distortion of hydrocarbon cations probed by infrared photodissociation spectroscopy.

Angewandte Chemie (International ed. in English) 20120723

Oxidation state delineation via U L(III)-edge XANES in a series of isostructural uranium coordination complexes.

Inorganic chemistry 20120716

Long-chain cationic derivatives of PTA (1,3,5-triaza-7-phosphaadamantane) as new components of potential non-viral vectors.

International journal of pharmaceutics 20120715

Synthesis of U(IV) imidos from Tp*2U(CH2Ph) (Tp* = hydrotris(3,5-dimethylpyrazolyl)borate) by extrusion of bibenzyl.

Dalton transactions (Cambridge, England : 2003) 20120714

Selective mode of action of guanidine-containing non-peptides at human NPFF receptors.

Journal of medicinal chemistry 20120712

Cost-effectiveness of saxagliptin (Onglyza®) in type 2 diabetes in Sweden.

Primary care diabetes 20120701

Effects of PKF275-055, a dipeptidyl peptidase-4 inhibitor, on the development of atherosclerotic lesions in apolipoprotein E-null mice.

Metabolism: clinical and experimental 20120701

Effect of the calcium sensing receptor on rat bone marrow-derived mesenchymal stem cell proliferation through the ERK1/2 pathway.

Molecular biology reports 20120701

A competitive chemiluminescence enzyme immunoassay for rapid and sensitive determination of enrofloxacin.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120701

Characterization of the in vitro and in vivo metabolism and disposition and cytochrome P450 inhibition/induction profile of saxagliptin in human.

Drug metabolism and disposition: the biological fate of chemicals 20120701

New adamantane derivatives with sigma affinity and antiproliferative activity.

Medicinal chemistry (Shariqah (United Arab Emirates)) 20120701

Pharmacokinetic study of saxagliptin in healthy Chinese subjects.

Clinical drug investigation 20120701

Drug-induced hypoglycaemia in type 2 diabetes.

Expert opinion on drug safety 20120701

5-(Adamantan-1-yl)-3-[(4-benzyl-piperazin-1-yl)meth-yl]-1,3,4-oxadiazole-2(3H)-thione.

Acta crystallographica. Section E, Structure reports online 20120701

N'-(Adamantan-2-yl-idene)benzo-hydrazide.

Acta crystallographica. Section E, Structure reports online 20120701

Sphingosine kinase isoforms as a therapeutic target in endocrine therapy resistant luminal and basal-A breast cancer.

Experimental biology and medicine (Maywood, N.J.) 20120701

[Effects of ionotropic glutamate receptor channel blockers ON sleep-waking organization in rats].

Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20120701

Vildagliptin inhibits oxidative stress and vascular damage in streptozotocin-induced diabetic rats.

International journal of cardiology 20120628

Bulky adamantanethiolate and cyclohexanethiolate ligands favor smaller gold nanoparticles with altered discrete sizes.

ACS nano 20120626

Nanodiamonds in sugar rings: an experimental and theoretical investigation of cyclodextrin-nanodiamond inclusion complexes.

Organic & biomolecular chemistry 20120621

Depigmenting activities of kojic acid derivatives without tyrosinase inhibitory activities.

Bioorganic & medicinal chemistry letters 20120615

7-Azabicyclo[2.2.1]heptane as a scaffold for the development of selective sigma-2 (σ2) receptor ligands.

Bioorganic & medicinal chemistry letters 20120615

Brain-derived neurotrophic factor activation of CaM-kinase kinase via transient receptor potential canonical channels induces the translation and synaptic incorporation of GluA1-containing calcium-permeable AMPA receptors.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20120613

Small organometallic compounds as antibacterial agents.

Dalton transactions (Cambridge, England : 2003) 20120607

Mechanically induced chemiluminescence from polymers incorporating a 1,2-dioxetane unit in the main chain.

Nature chemistry 20120603

Effects of vildagliptin on postprandial markers of bone resorption and calcium homeostasis in recently diagnosed, well-controlled type 2 diabetes patients.

Journal of diabetes 20120601

Saxagliptin and sitagliptin in adult patients with type 2 diabetes: a systematic review and meta-analysis.

Diabetes, obesity & metabolism 20120601

The detection of the urinary metabolites of 3-[(adamantan-1-yl)carbonyl]-1-pentylindole (AB-001), a novel cannabimimetic, by gas chromatography-mass spectrometry.

Drug testing and analysis 20120601

Effectiveness of synthetic trioxolane OZ78 against Schistosoma japonicum in mice and rabbits.

Parasitology research 20120601

Combination therapy with metformin plus vildagliptin in type 2 diabetes mellitus.

Expert opinion on pharmacotherapy 20120601

Attenuation of cisplatin-induced renal injury by inhibition of soluble epoxide hydrolase involves nuclear factor κB signaling.

The Journal of pharmacology and experimental therapeutics 20120601

Vildagliptin added to metformin on β-cell function after a euglycemic hyperinsulinemic and hyperglycemic clamp in type 2 diabetes patients.

Diabetes technology & therapeutics 20120601

Cardiovascular protection of activating KATP channel during ischemia-reperfusion acidosis.

Shock (Augusta, Ga.) 20120601

Cucurbituril adamantanediazirine complexes and consequential carbene chemistry.

The Journal of organic chemistry 20120601

New adamantane derivatives can overcome resistance of influenza A(H1N1)pdm2009 and A(H3N2) viruses to remantadine.

Bulletin of experimental biology and medicine 20120601

Trapping of bulky guests inside dimeric molecular capsules formed by a deep-cavity cavitand.

The Journal of organic chemistry 20120518

Sterically congested adamantylnaphthalene quinone methides.

The Journal of organic chemistry 20120518

Synthesis, σ₁, σ₂-receptors binding affinity and antiproliferative action of new C1-substituted adamantanes.

Bioorganic & medicinal chemistry 20120515

Screening a library of 1600 adamantyl ureas for anti-Mycobacterium tuberculosis activity in vitro and for better physical chemical properties for bioavailability.

Bioorganic & medicinal chemistry 20120515

Infrared spectrum and structure of the adamantane cation: direct evidence for Jahn-Teller distortion.

Angewandte Chemie (International ed. in English) 20120514

A POSS-based supramolecular amphiphile and its hierarchical self-assembly behaviors.

Macromolecular rapid communications 20120514

Structure-dependent pseudoreceptor intracellular traffic of adamantyl globotriaosyl ceramide mimics.

The Journal of biological chemistry 20120511

Head-to-head prenyl tranferases: anti-infective drug targets.

Journal of medicinal chemistry 20120510

Electron paramagnetic resonance spectroscopic evidence for the interaction of HAlOH with water molecules.

The journal of physical chemistry. A 20120503

CD26/DPP-4 inhibition recruits regenerative stem cells via stromal cell-derived factor-1 and beneficially influences ischaemia-reperfusion injury in mouse lung transplantation.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20120501

SQ109 and PNU-100480 interact to kill Mycobacterium tuberculosis in vitro.

The Journal of antimicrobial chemotherapy 20120501

RF9 powerfully stimulates gonadotrophin secretion in the ewe: evidence for a seasonal threshold of sensitivity.

Journal of neuroendocrinology 20120501

An update in incretin-based therapy: a focus on dipeptidyl peptidase--4 inhibitors.

Current diabetes reviews 20120501

Stability-indicating RP-LC method for the determination of vildagliptin and mass spectrometry detection for a main degradation product.

Journal of chromatographic science 20120501

3-(Adamantan-1-yl)-4-ethyl-1H-1,2,4-triazole-5(4H)-thione.

Acta crystallographica. Section E, Structure reports online 20120501

2-{[5-(Adamantan-1-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfan-yl}-N,N-dimethyl-ethanamine.

Acta crystallographica. Section E, Structure reports online 20120501

3-(1-Adamant-yl)-4-amino-1-(2-benzoyl-1-phenyl-eth-yl)-1H-1,2,4-triazol-5(4H)-thione.

Acta crystallographica. Section E, Structure reports online 20120501

1-(Adamantan-1-yl)-3-(4-fluoro-phen-yl)thio-urea.

Acta crystallographica. Section E, Structure reports online 20120501

On-column ligand exchange for structure-based drug design: a case study with human 11β-hydroxysteroid dehydrogenase type 1.

Acta crystallographica. Section F, Structural biology and crystallization communications 20120501

Selective homogeneous and heterogeneous catalytic conversion of methanol/dimethyl ether to triptane.

Accounts of chemical research 20120417

Pyrazine-based Syk kinase inhibitors.

Bioorganic & medicinal chemistry letters 20120415

Relationships between the islets blood flow, nitric oxide, insulin, and cytosolic calcium in rat pancreatic islets: effects of DPP-IV inhibitor vildagliptin.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120411

Iron(II) complexes of new hexadentate 1,1,1-tris-(iminomethyl)ethane podands, and their 7-methyl-1,3,5-triazaadamantane rearrangement products.

Dalton transactions (Cambridge, England : 2003) 20120407

Construction of a graphene oxide based noncovalent multiple nanosupramolecular assembly as a scaffold for drug delivery.

Chemistry (Weinheim an der Bergstrasse, Germany) 20120402

The role of endogenous neurotensin in psychostimulant-induced disruption of prepulse inhibition and locomotion.

Schizophrenia research 20120401

Evaluation of antiproliferative effect of N-(alkyladamantyl)phthalimides in vitro.

Chemical biology & drug design 20120401

Adding saxagliptin to extended-release metformin vs. uptitrating metformin dosage.

Diabetes, obesity & metabolism 20120401

DPP-4 inhibitors in the management of type 2 diabetes: a critical review of head-to-head trials.

Diabetes & metabolism 20120401

Effect of saxagliptin as add-on therapy in patients with poorly controlled type 2 diabetes on insulin alone or insulin combined with metformin.

Current medical research and opinion 20120401

Dipeptidyl peptidase-4 inhibitors: 3 years of experience.

Diabetes technology & therapeutics 20120401

Highly sensitive colorimetric enzyme-linked oligonucleotide assay based on cyclodextrin-modified polymeric surfaces.

Analytical and bioanalytical chemistry 20120401

Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane.

Nature chemical biology 20120401

Synthesis and photodynamic properties of adamantylethoxy Zn(II) phthalocyanine derivatives in different media and in human red blood cells.

European journal of medicinal chemistry 20120401

Reply to: Ahren B et al. Mechanisms of action of the dipeptidyl peptidase-4 inhibitor vildagliptin in humans. Diabetes Obes Metab 2011; 13(9): 775-783 and Ahren B et al. Clinical evidence and mechanistic basis for vildagliptin's action when added to metformin. Diabetes Obes Metab 2011; 13(3): 193-203.

Diabetes, obesity & metabolism 20120401

Inhibition of vascular adenosine triphosphate-sensitive potassium channels by sympathetic tone during sepsis.

Critical care medicine 20120401

Effects of meal timing relative to dosing on the pharmacokinetics and pharmacodynamics of vildagliptin in Japanese patients with Type 2 diabetes.

International journal of clinical pharmacology and therapeutics 20120401

Synthesis and immunostimulating properties of novel adamant-1-yl tripeptides.

Chemistry & biodiversity 20120401

(E)-N-Benzyl-ideneadamantan-1-amine.

Acta crystallographica. Section E, Structure reports online 20120401

Bis(adamantan-1-aminium) carbonate.

Acta crystallographica. Section E, Structure reports online 20120401

3,5-Bis(adamantan-1-yl)-1-meth-oxy-benzene.

Acta crystallographica. Section E, Structure reports online 20120401

[Effects of ionotropic glutamate receptor channel blockers on the development of audiogenic seizures in Krushinski-Molodkina rats].

Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20120401

Enhanced asymmetric induction for the copolymerization of CO2 and cyclohexene oxide with unsymmetric enantiopure salenCo(III) complexes: synthesis of crystalline CO2-based polycarbonate.

Journal of the American Chemical Society 20120328

Generation of diamondoid hydrocarbons as confined compounds in SAPO-34 catalyst in the conversion of methanol.

Chemical communications (Cambridge, England) 20120325

Synthesis of uranium(VI) terminal oxo complexes: molecular geometry driven by the inverse trans-influence.

Journal of the American Chemical Society 20120321

Solution-phase synthesis of branched DNA hybrids based on dimer phosphoramidites and phenolic or nucleosidic cores.

The Journal of organic chemistry 20120316

Solution-phase synthesis of branched DNA hybrids via H-phosphonate dimers.

The Journal of organic chemistry 20120316

On the origin of siphonariid polypropionates: total synthesis of caloundrin B and its isomerization to siphonarin B.

Organic letters 20120316

Infectious diseases: Transporter targeted in tuberculosis.

Nature chemical biology 20120316

Activation of C-O and C-C bonds and formation of novel HAlOH-ether complexes: an EPR study of the reaction of ground-state Al atoms with methylethyl ether and diethyl ether.

The journal of physical chemistry. A 20120315

Liquid chromatography and tandem mass spectrometry method for the quantitative determination of saxagliptin and its major pharmacologically active 5-monohydroxy metabolite in human plasma: method validation and overcoming specific and non-specific binding at low concentrations.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120315

Polycyclic cage structures as lipophilic scaffolds for neuroactive drugs.

ChemMedChem 20120305

Pharmacokinetics and pharmacodynamics of AR9281, an inhibitor of soluble epoxide hydrolase, in single- and multiple-dose studies in healthy human subjects.

Journal of clinical pharmacology 20120301

Efficacy and safety of saxagliptin in drug-naïve Asian patients with type 2 diabetes mellitus: a randomized controlled trial.

Diabetes/metabolism research and reviews 20120301

Involvement of calcium-sensing receptor in oxLDL-induced MMP-2 production in vascular smooth muscle cells via PI3K/Akt pathway.

Molecular and cellular biochemistry 20120301

Characterization of COR627 and COR628, two novel positive allosteric modulators of the GABA(B) receptor.

The Journal of pharmacology and experimental therapeutics 20120301

Saxagliptin for the treatment of type 2 diabetes mellitus: focus on recent studies.

Annals of medicine 20120301

Soluble epoxide hydrolase inhibition improves myocardial perfusion and function in experimental heart failure.

Journal of molecular and cellular cardiology 20120301

Sphingosine kinase inhibition exerts both pro- and anti-atherogenic effects in low-density lipoprotein receptor-deficient (LDL-R(-/-)) mice.

Thrombosis and haemostasis 20120301

Reversed chloroquine molecules as a strategy to overcome resistance in malaria.

Current topics in medicinal chemistry 20120301

Cost effectiveness of saxagliptin and metformin versus sulfonylurea and metformin in the treatment of type 2 diabetes mellitus in Germany: a Cardiff diabetes model analysis.

Clinical drug investigation 20120301

Adamantyl N-benzylbenzamide: new series of depigmentation agents with tyrosinase inhibitory activity.

Bioorganic & medicinal chemistry letters 20120301

Saxagliptin plus metformin combination in patients with type 2 diabetes and renal impairment.

Expert opinion on drug metabolism & toxicology 20120301

Impact of the dipeptidyl peptidase-4 inhibitor vildagliptin on glucose tolerance and β-cell function and mass in insulin receptor substrate-2-knockout mice fed a high-fat diet.

Endocrinology 20120301

Clinical pharmacokinetics and pharmacodynamics of vildagliptin.

Clinical pharmacokinetics 20120301

3-(Adamantan-1-yl)-4-(prop-2-en-1-yl)-1H-1,2,4-triazole-5(4H)-thione.

Acta crystallographica. Section E, Structure reports online 20120301

3-(Adamantan-1-yl)-1-[(4-ethyl-piperazin-1-yl)meth-yl]-4-[(E)-(4-hy-droxy-benzyl-idene)amino]-1H-1,2,4-triazole-5(4H)-thione.

Acta crystallographica. Section E, Structure reports online 20120301

2-(Adamantan-1-yl)-5-(4-nitro-phen-yl)-1,3,4-oxadiazole.

Acta crystallographica. Section E, Structure reports online 20120301

Mechanism-based population modelling of the effects of vildagliptin on GLP-1, glucose and insulin in patients with type 2 diabetes.

British journal of clinical pharmacology 20120301

Mechanism-based population pharmacokinetic modelling in diabetes: vildagliptin as a tight binding inhibitor and substrate of dipeptidyl peptidase IV.

British journal of clinical pharmacology 20120301

2-Acylamino-6-pyridones: breaking of an intramolecular hydrogen bond by self-association and complexation with double and triple hydrogen bonding counterparts. Uncommon steric effect on intermolecular interactions.

The Journal of organic chemistry 20120217

Experimental and computational bridgehead C-H bond dissociation enthalpies.

The Journal of organic chemistry 20120217

Click modification in the N6 region of A3 adenosine receptor-selective carbocyclic nucleosides for dendrimeric tethering that preserves pharmacophore recognition.

Bioconjugate chemistry 20120215

Cyclodextrin polymer nanoassemblies: strategies for stability improvement.

Biomacromolecules 20120213

Supramolecular polymorphism of the 1:1 molecular salt (adamantane-1-carboxylate-3,5,7-tricarboxylic acid)·(hexamethylenetetraminium). A 'failed' crystal engineering attempt.

Chemical communications (Cambridge, England) 20120211

Intra- and intermolecular reaction selectivities of γ-substituted adamantanylidenes.

The Journal of organic chemistry 20120203

Stability and bioactivity studies on dipeptidyl peptidase IV resistant glucogan-like peptide-1 analogues.

Protein and peptide letters 20120201

Smart DNA vectors based on cyclodextrin polymers: compaction and endosomal release.

Pharmaceutical research 20120201

Post-conditioning protecting rat cardiomyocytes from apoptosis via attenuating calcium-sensing receptor-induced endo(sarco)plasmic reticulum stress.

Molecular and cellular biochemistry 20120201

Dipeptidyl peptidase IV inhibitor attenuates kidney injury in streptozotocin-induced diabetic rats.

The Journal of pharmacology and experimental therapeutics 20120201

Stimulation of Ca2+-sensing receptor inhibits the basolateral 50-pS K channels in the thick ascending limb of rat kidney.

Biochimica et biophysica acta 20120201

Role of p21 as a determinant of 1,6-Bis[4-(4-amino-3-hydroxyphenoxy)phenyl] diamantane response in human HCT-116 colon carcinoma cells.

Oncology reports 20120201

In vivo treatment of tumors using host-guest conjugated nanoparticles functionalized with doxorubicin and therapeutic gene pTRAIL.

Biomaterials 20120201

3-(Adamantan-1-yl)-4-phenyl-1-[(4-phenyl-piperazin-1-yl)meth-yl]-1H-1,2,4-triazole-5(4H)-thione.

Acta crystallographica. Section E, Structure reports online 20120201

Cytomimetic large-scale vesicle aggregation and fusion based on host-guest interaction.

Langmuir : the ACS journal of surfaces and colloids 20120131

Peroxisome proliferator-activated receptors (PPARs) have multiple binding points that accommodate ligands in various conformations: phenylpropanoic acid-type PPAR ligands bind to PPAR in different conformations, depending on the subtype.

Journal of medicinal chemistry 20120126

Saxagliptin: a review of its use as combination therapy in the management of type 2 diabetes mellitus in the EU.

Drugs 20120122

Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells.

Oncogene 20120119

Reaction mechanism in crystalline solids: kinetics and conformational dynamics of the Norrish type II biradicals from α-adamantyl-p-methoxyacetophenone.

Journal of the American Chemical Society 20120118

A novel long acting DPP-IV inhibitor PKF-275-055 stimulates β-cell proliferation resulting in improved glucose homeostasis in diabetic rats.

Biochemical pharmacology 20120115

Rotationally resolved infrared spectroscopy of adamantane.

The Journal of chemical physics 20120114

Responsive small molecular hydrogels based on adamantane-peptides for cell culture.

The journal of physical chemistry. B 20120112

Analogues of orphan nuclear receptor small heterodimer partner ligand and apoptosis inducer (E)-4-[3-(1-adamantyl)-4-hydroxyphenyl]-3-chlorocinnamic acid. 2. Impact of 3-chloro group replacement on inhibition of proliferation and induction of apoptosis of leukemia and cancer cell lines.

Journal of medicinal chemistry 20120112

Supramolecular host-guest interaction for labeling and detection of cellular biomarkers.

Angewandte Chemie (International ed. in English) 20120109

Planar chiral (η6-arene)Cr(CO)3 containing carboxylic acid derivatives: synthesis and use in the preparation of organometallic analogues of the antibiotic platensimycin.

Dalton transactions (Cambridge, England : 2003) 20120107

Activation of C-Cl by ground-state aluminum atoms: an EPR and DFT investigation.

Physical chemistry chemical physics : PCCP 20120107

Involvement of neuropeptide FF receptors in neuroadaptive responses to acute and chronic opiate treatments.

British journal of pharmacology 20120101

Sphingosine kinase-2 inhibition improves mitochondrial function and survival after hepatic ischemia-reperfusion.

Journal of hepatology 20120101

Treatment of genetically obese mice with the iminosugar N-(5-adamantane-1-yl-methoxy-pentyl)-deoxynojirimycin reduces body weight by decreasing food intake and increasing fat oxidation.

Metabolism: clinical and experimental 20120101

Cytotoxic properties of Adamantyl isothiocyanate and potential in vivo metabolite adamantyl-N-acetylcystein in gynecological cancer cells.

Chemical biology & drug design 20120101

Beneficial effects of PKF275-055, a novel, selective, orally bioavailable, long-acting dipeptidyl peptidase IV inhibitor in streptozotocin-induced diabetic peripheral neuropathy.

The Journal of pharmacology and experimental therapeutics 20120101

The cost-effectiveness of saxagliptin versus NPH insulin when used in combination with other oral antidiabetes agents in the treatment of type 2 diabetes mellitus in Poland.

Diabetes technology & therapeutics 20120101

Kisspeptin signaling is indispensable for neurokinin B, but not glutamate, stimulation of gonadotropin secretion in mice.

Endocrinology 20120101

Functional evidence for D-serine inhibition of non-N-methyl-D-aspartate ionotropic glutamate receptors in retinal neurons.

The European journal of neuroscience 20120101

Metformin + saxagliptin for type 2 diabetes.

Expert opinion on pharmacotherapy 20120101

Modulation of neuropeptide FF (NPFF) receptors influences the expression of amphetamine-induced conditioned place preference and amphetamine withdrawal anxiety-like behavior in rats.

Peptides 20120101

A pharmacometric approach to quantify the impact of chronic kidney disease and hemodialysis on systemic drug exposure: application to saxagliptin.

Journal of clinical pharmacology 20120101

Synthetic peroxides as potent antimalarials. News and views.

Current topics in medicinal chemistry 20120101

Saxagliptin for the treatment of type 2 diabetes mellitus: assessing cardiovascular data.

Cardiovascular diabetology 20120101

A new benzoylphloroglucinol derivative with an adamantyl skeleton and other constituents from Garcinia multiflora: effects on neutrophil pro-inflammatory responses.

Chemistry & biodiversity 20120101

A protocol for active surveillance of acute myocardial infarction in association with the use of a new antidiabetic pharmaceutical agent.

Pharmacoepidemiology and drug safety 20120101

Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy.

Theranostics 20120101

Rapid evaluation in whole blood culture of regimens for XDR-TB containing PNU-100480 (sutezolid), TMC207, PA-824, SQ109, and pyrazinamide.

PloS one 20120101

The anticipated severity of a '1918-like' influenza pandemic in contemporary populations: the contribution of antibacterial interventions.

PloS one 20120101

Use of Linear Free Energy Relationships (LFERs) to elucidate the mechanisms of reaction of a γ-methyl-β-alkynyl and an ortho-substituted aryl chloroformate ester.

International journal of molecular sciences 20120101

Adamantane-substituted guanylhydrazones: novel inhibitors of butyrylcholinesterase.

Bioorganic chemistry 20120101

Effect of the leaving group and solvent combination on the LFER reaction constants.

International journal of molecular sciences 20120101

Syntheses and in-vitro evaluation of novel adamantane based γ-secretase inhibitors.

Current medicinal chemistry 20120101

Monoclonal antibodies targeting the synthetic peptide corresponding to the polybasic cleavage site on H5N1 influenza hemagglutinin.

Journal of biomedical science 20120101

The synergistic effect of valsartan and LAF237 [(S)-1-[(3-hydroxy-1-adamantyl)ammo]acetyl-2-cyanopyrrolidine] on vascular oxidative stress and inflammation in type 2 diabetic mice.

Experimental diabetes research 20120101

Potency, selectivity and prolonged binding of saxagliptin to DPP4: maintenance of DPP4 inhibition by saxagliptin in vitro and ex vivo when compared to a rapidly-dissociating DPP4 inhibitor.

BMC pharmacology 20120101

Synthesis and antimicrobial studies of some novel bis-[1,3,4]thiadiazole and bis-thiazole pendant to thieno[2,3-b]thiophene moiety.

International journal of molecular sciences 20120101

Cyclodextrin-containing polymers: versatile platforms of drug delivery materials.

Journal of drug delivery 20120101

Challenges for accurate and prompt molecular diagnosis of clades of highly pathogenic avian influenza H5N1 viruses emerging in Vietnam.

Avian pathology : journal of the W.V.P.A 20120101

The fluorescence neuraminidase inhibition assay: a functional method for detection of influenza virus resistance to the neuraminidase inhibitors.

Methods in molecular biology (Clifton, N.J.) 20120101

Soluble epoxide hydrolase activity determines the severity of ischemia-reperfusion injury in kidney.

PloS one 20120101

Electrospray ionization mass spectrometry: a technique to access the information beyond the molecular weight of the analyte.

International journal of analytical chemistry 20120101

Vildagliptin selectively ameliorates GLP-1, GLUT4, SREBP-1c mRNA levels and stimulates β-cell proliferation resulting in improved glucose homeostasis in rats with streptozotocin-induced diabetes.

Journal of diabetes and its complications 20120101

Evidence to support the use of vildagliptin monotherapy in the treatment of type 2 diabetes mellitus.

Vascular health and risk management 20120101

Effects of a vildagliptin/metformin combination on markers of atherosclerosis, thrombosis, and inflammation in diabetic patients with coronary artery disease.

Cardiovascular diabetology 20120101

Cell number and transfection volume dependent peptide nucleic acid antisense activity by cationic delivery methods.

Artificial DNA, PNA & XNA 20120101

Long-lasting alterations in membrane properties, k(+) currents, and glutamatergic synaptic currents of nucleus accumbens medium spiny neurons in a rat model of alcohol dependence.

Frontiers in neuroscience 20120101

[Effect of ladasten on antenatal and postnatal development].

Eksperimental'naia i klinicheskaia farmakologiia 20120101

The atypical retinoid E-3-(3'-Adamantan-1-yl-4'-methoxybiphenyl-4-yl)-2-propenoic acid (ST1898) displays comedolytic activity in the rhino mouse model.

European journal of dermatology : EJD 20120101

Cost-effectiveness and budget impact of saxagliptine as additional therapy to metformin for the treatment of diabetes mellitus type 2 in the Brazilian private health system.

Revista da Associacao Medica Brasileira (1992) 20120101

Magic angle spinning solid-state NMR experiments for structural characterization of proteins.

Methods in molecular biology (Clifton, N.J.) 20120101

[Ladasten versus placebo effect self-evaluated by neurasthenia patients with different EEG alpha rhythm types].

Eksperimental'naia i klinicheskaia farmakologiia 20120101

Inhibition of sphingosine kinase-2 suppresses inflammation and attenuates graft injury after liver transplantation in rats.

PloS one 20120101

Comparison of vildagliptin twice daily vs. sitagliptin once daily using continuous glucose monitoring (CGM): crossover pilot study (J-VICTORIA study).

Cardiovascular diabetology 20120101

[Adamantane derivate enhances cerebral blood flow under conditions of ischemic brain damage].

Eksperimental'naia i klinicheskaia farmakologiia 20120101

Microfabricated inserts for magic angle coil spinning (MACS) wireless NMR spectroscopy.

PloS one 20120101

Cyclodextrin-based [1]rotaxanes on gold nanoparticles.

International journal of molecular sciences 20120101

Platensimycin and platencin biosynthesis in Streptomyces platensis, showcasing discovery and characterization of novel bacterial diterpene synthases.

Methods in enzymology 20120101

[Development of versatile oxidation systems based on the design of oxoammonium salts].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20120101

Attenuation of renovascular damage in Zucker diabetic fatty rat by NWT-03, an egg protein hydrolysate with ACE- and DPP4-inhibitory Activity.

PloS one 20120101

Pancreatitis with pancreatic tail swelling associated with incretin-based therapies detected radiologically in two cases of diabetic patients with end-stage renal disease.

Internal medicine (Tokyo, Japan) 20120101

Speedy and clean hypervalent iodine/nitroxyl radical mediated oxidation of alcohols using recyclable adamantane reagent with highly active 2-azaadamantane-N-oxyl organocatalyst.

Chemical & pharmaceutical bulletin 20120101

Amphiphilic star-block copolymers and supramolecular transformation of nanogel-like micelles to nanovesicles.

Chemical communications (Cambridge, England) 20111228

Nonequilibrium Fermi golden rule for electronic transitions through conical intersections.

The Journal of chemical physics 20111221

Kinetic and mechanistic insight into the thermodynamic degradation of saxagliptin.

The Journal of organic chemistry 20111216

Huge dielectric response and molecular motions in paddle-wheel [Cu(II)2(adamantylcarboxylate)4(DMF)2]⋅(DMF)2.

Chemistry (Weinheim an der Bergstrasse, Germany) 20111216

Adamantane-platinum conjugate hosted in β-cyclodextrin: enhancing transport and cytotoxicity by noncovalent modification.

Bioorganic & medicinal chemistry letters 20111215

Investigating the antimalarial action of 1,2,4-trioxolanes with fluorescent chemical probes.

Journal of medicinal chemistry 20111208

Thermoresponsive supramolecular dendronized polymers.

Chemistry, an Asian journal 20111202

Combined anticancer effects of sphingosine kinase inhibitors and sorafenib.

Investigational new drugs 20111201

Long-term treatment with the dipeptidyl peptidase-4 inhibitor saxagliptin in patients with type 2 diabetes mellitus and renal impairment: a randomised controlled 52-week efficacy and safety study.

International journal of clinical practice 20111201

Design, synthesis and in vitro evaluation of bridgehead fluoromethyl analogs of N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-N-(pyridin-2-yl)cyclohexanecarboxamide (WAY-100635) for the 5-HT(1A) receptor.

European journal of medicinal chemistry 20111201

Sterically congested quinone methides in photodehydration reactions of 4-hydroxybiphenyl derivatives and investigation of their antiproliferative activity.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20111201

(1-Adamant-yl)(3-amino-phen-yl)methanone.

Acta crystallographica. Section E, Structure reports online 20111201

[Incretin-based therapy for treating patients with type 2 diabetes].

Orvosi hetilap 20111127

Oxidative Prins-pinacol tandem process mediated by a hypervalent iodine reagent: scope, limitations, and applications.

The Journal of organic chemistry 20111118

Photochemical generation and reactivity of carbenes within an organic cavitand and capsule: photochemistry of adamantanediazirines.

Organic letters 20111118

Simultaneous interactions of anions and cations with cyclohexane and adamantane: aliphatic cyclic hydrocarbons as charge insulators.

The journal of physical chemistry. A 20111117

Design, synthesis, and SAR studies of novel polycyclic acids as potent and selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1).

Bioorganic & medicinal chemistry letters 20111115

Multiplexing interactions to control antibiotic release from cyclodextrin hydrogels.

Macromolecular bioscience 20111110

Structural investigation of rimantadine inhibition of the AM2-BM2 chimera channel of influenza viruses.

Structure (London, England : 1993) 20111109

Highly active ethylene polymerization and regioselective 1-hexene oligomerization using zirconium and titanium catalysts with tridentate [ONO] ligands.

Inorganic chemistry 20111107

Synthesis, antimicrobial and antiproliferative activity of novel silver(I) tris(pyrazolyl)methanesulfonate and 1,3,5-triaza-7-phosphadamantane complexes.

Inorganic chemistry 20111107

Synthesis and electronic structure determination of N-alkyl-substituted bis(imino)pyridine iron imides exhibiting spin crossover behavior.

Journal of the American Chemical Society 20111102

Selective inhibition of striatal fast-spiking interneurons causes dyskinesias.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20111102

Adaphostin promotes caffeine-evoked autocrine Fas-mediated death pathway activation in Bcr/Abl-positive leukaemia cells.

The Biochemical journal 20111101

Inhibition of epoxy-eicosanoid degradation improves the tocolytic effects of indomethacin in the uterus from pregnant women.

Prostaglandins & other lipid mediators 20111101

Naja nigricollis CMS-9 enhances the mitochondria-mediated death pathway in adaphostin-treated human leukaemia U937 cells.

Clinical and experimental pharmacology & physiology 20111101

Target-mediated metabolism and target-mediated drug disposition of the DPPIV inhibitor AMG 222.

Xenobiotica; the fate of foreign compounds in biological systems 20111101

Efficacy and safety of saxagliptin added to metformin in Asian people with type 2 diabetes mellitus: a randomized controlled trial.

Diabetes research and clinical practice 20111101

Platensimycin and platencin: promising antibiotics for future application in human medicine.

The Journal of antibiotics 20111101

Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents.

Bioorganic & medicinal chemistry 20111101

In vivo transfection using cyclodextrin-containing polycations.

Cold Spring Harbor protocols 20111101

The design and rationale of the saxagliptin assessment of vascular outcomes recorded in patients with diabetes mellitus-thrombolysis in myocardial infarction (SAVOR-TIMI) 53 study.

American heart journal 20111101

1-(1-Adamantylmeth-yl)-1H-benzimidazole.

Acta crystallographica. Section E, Structure reports online 20111101

N'-(Adamantan-2-yl-idene)thio-phene-2-carbohydrazide.

Acta crystallographica. Section E, Structure reports online 20111101

Prospective of Genomics in Revealing Transmission, Reassortment and Evolution of Wildlife-Borne Avian Influenza A (H5N1) Viruses.

Current genomics 20111101

Emerging role of DPP-4 inhibitor Vildagliptin in the management of type-2 diabetes.

The Journal of the Association of Physicians of India 20111101

NMR study of ligand exchange and electron self-exchange between oxo-centered trinuclear clusters [Fe3(μ3-O)(μ-O2CR)6(4-R'py)3](+/0).

Inorganic chemistry 20111017

Nickel(II) complexes of tripodal 4N ligands as catalysts for alkane oxidation using m-CPBA as oxidant: ligand stereoelectronic effects on catalysis.

Dalton transactions (Cambridge, England : 2003) 20111007

Mono- and dinuclear iron complexes of bis(1-methylimidazol-2-yl)ketone (bik): structure, magnetic properties, and catalytic oxidation studies.

Inorganic chemistry 20111003

Safety and efficacy of vildagliptin versus placebo in patients with type 2 diabetes and moderate or severe renal impairment: a prospective 24-week randomized placebo-controlled trial.

Diabetes, obesity & metabolism 20111001

Impact of down-regulation of starch branching enzyme IIb in rice by artificial microRNA- and hairpin RNA-mediated RNA silencing.

Journal of experimental botany 20111001

Recognition properties of cucurbit[7]uril self-assembled monolayers studied with force spectroscopy.

Langmuir : the ACS journal of surfaces and colloids 20110920

N-Arylalkyl-2-azaadamantanes as cage-expanded polycarbocyclic sigma (σ) receptor ligands.

Bioorganic & medicinal chemistry letters 20110915

Identification of SQ609 as a lead compound from a library of dipiperidines.

Bioorganic & medicinal chemistry letters 20110915

Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection.

Nature 20110915

Synthesis and SAR requirements of adamantane-colchicine conjugates with both microtubule depolymerizing and tubulin clustering activities.

Bioorganic & medicinal chemistry 20110915

[Dipeptidyl-peptidase-4 inhibitors (gliptins): a new class of oral antidiabetic drugs].

Orvosi hetilap 20110911

Size-controlled nanoassemblies based on cyclodextrin-modified dextrans.

Macromolecular bioscience 20110909

1-Deoxy-D-galactonojirimycins with dansyl capped N-substituents as β-galactosidase inhibitors and potential probes for GM1 gangliosidosis affected cell lines.

Carbohydrate research 20110906

Adamantyl ethanone pyridyl derivatives: potent and selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1.

ChemMedChem 20110905

Mechanisms of action of the dipeptidyl peptidase-4 inhibitor vildagliptin in humans.

Diabetes, obesity & metabolism 20110901

Effects of saxagliptin on β-cell stimulation and insulin secretion in patients with type 2 diabetes.

Diabetes, obesity & metabolism 20110901

The metabolic syndrome influences the response to incretin-based therapies.

Acta diabetologica 20110901

Experimental studies and modeling of drug release from a tunable affinity-based drug delivery platform.

Annals of biomedical engineering 20110901

Efficacy of saxagliptin as an add-on to oral monotherapy in the phase 3 clinical development program: predictive factors of the treatment response in type 2 diabetes.

Annales d'endocrinologie 20110901

Vildagliptin improves endothelium-dependent vasodilatation in type 2 diabetes.

Diabetes care 20110901

Platensimycin and its relatives: a recent story in the struggle to develop new naturally derived antibiotics.

Natural product reports 20110901

[Influenza : clinical symptoms, diagnostics and therapy].

Der Internist 20110901

Multidrug resistant 2009 A/H1N1 influenza clinical isolate with a neuraminidase I223R mutation retains its virulence and transmissibility in ferrets.

PLoS pathogens 20110901

rac-2-{[1-(1-Adamant-yl)eth-yl]imino-meth-yl}-5-meth-oxy-phenol.

Acta crystallographica. Section E, Structure reports online 20110901

2-(1-Adamant-yl)-1-(3-amino-phen-yl)ethanol.

Acta crystallographica. Section E, Structure reports online 20110901

Thermodynamic properties of adamantane revisited.

The journal of physical chemistry. B 20110825

Synthesis and characterization of three-coordinate Ni(III)-imide complexes.

Journal of the American Chemical Society 20110824

HYDRAmers: design, synthesis and characterization of different generation novel Hydra-like dendrons based on multifunctionalized adamantane.

Chemical communications (Cambridge, England) 20110821

Cyclodextrin and adamantane host-guest interactions of modified hyperbranched poly(ethylene imine) as mimetics for biological membranes.

Angewandte Chemie (International ed. in English) 20110816

Investigations on the 4-quinolone-3-carboxylic acid motif. 4. Identification of new potent and selective ligands for the cannabinoid type 2 receptor with diverse substitution patterns and antihyperalgesic effects in mice.

Journal of medicinal chemistry 20110811

Ordered phases of encapsulated diamondoids into carbon nanotubes.

Nanotechnology 20110805

Ongoing clinical trials evaluating the cardiovascular safety and efficacy of therapeutic approaches to diabetes mellitus.

The American journal of cardiology 20110802

11β-hydroxysteroid dehydrogenases and the brain: from zero to hero, a decade of progress.

Frontiers in neuroendocrinology 20110801

Beta cell function following 1 year vildagliptin or placebo treatment and after 12 week washout in drug-naive patients with type 2 diabetes and mild hyperglycaemia: a randomised controlled trial.

Diabetologia 20110801

Dipeptidyl peptidase-4 inhibition increases portal concentrations of intact glucagon-like peptide-1 (GLP-1) to a greater extent than peripheral concentrations in anaesthetised pigs.

Diabetologia 20110801

Discovery of adamantyl heterocyclic ketones as potent 11β-hydroxysteroid dehydrogenase type 1 inhibitors.

ChemMedChem 20110801

Could LogP be a principal determinant of biological activity in 18-crown-6 ethers? Synthesis of biologically active adamantane-substituted diaza-crowns.

European journal of medicinal chemistry 20110801

Vildagliptin in the treatment of type 2 diabetes mellitus.

Expert opinion on pharmacotherapy 20110801

Small-molecule hydrophobic tagging-induced degradation of HaloTag fusion proteins.

Nature chemical biology 20110801

Saxagliptin: a clinical review in the treatment of type 2 diabetes mellitus.

Clinical therapeutics 20110801

New synthesis of 6[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid and evaluation of the influence of adamantyl group on the DNA binding of a naphthoic retinoid.

Bioorganic chemistry 20110801

Place in therapy for liraglutide and saxagliptin for type 2 diabetes and FDA liraglutide warning.

Southern medical journal 20110801

N-(2-Hy-droxy-benz-yl)adamantan-1-aminium bromide.

Acta crystallographica. Section E, Structure reports online 20110801

Novel lipophilic acetohydroxamic acid derivatives based on conformationally constrained spiro carbocyclic 2,6-diketopiperazine scaffolds with potent trypanocidal activity.

Journal of medicinal chemistry 20110728

A biomimetic principle for the chemical modification of metal surfaces: synthesis of tripodal catecholates as analogues of siderophores and mussel adhesion proteins.

Chemistry (Weinheim an der Bergstrasse, Germany) 20110725

The Suzuki reaction in aqueous media promoted by P, N ligands.

Molecules (Basel, Switzerland) 20110725

Amperometric detection of antibodies in serum: performance of self-assembled cyclodextrin/cellulose polymer interfaces as antigen carriers.

Organic & biomolecular chemistry 20110707

Saxagliptin, a potent, selective inhibitor of DPP-4, does not alter the pharmacokinetics of three oral antidiabetic drugs (metformin, glyburide or pioglitazone) in healthy subjects.

Diabetes, obesity & metabolism 20110701

Resistance mutations define specific antiviral effects for inhibitors of the hepatitis C virus p7 ion channel.

Hepatology (Baltimore, Md.) 20110701

Ligand-dependent regulation of the activity of the orphan nuclear receptor, small heterodimer partner (SHP), in the repression of bile acid biosynthetic CYP7A1 and CYP8B1 genes.

Molecular endocrinology (Baltimore, Md.) 20110701

Comparison of the dipeptidyl peptidase-4 inhibitor vildagliptin and the sulphonylurea gliclazide in combination with metformin, in Muslim patients with type 2 diabetes mellitus fasting during Ramadan: results of the VECTOR study.

Current medical research and opinion 20110701

Thorough QT study of the effects of vildagliptin, a dipeptidyl peptidase IV inhibitor, on cardiac repolarization and conduction in healthy volunteers.

Current medical research and opinion 20110701

Effect of rifampicin on the pharmacokinetics and pharmacodynamics of saxagliptin, a dipeptidyl peptidase-4 inhibitor, in healthy subjects.

British journal of clinical pharmacology 20110701

Synthesis and evaluation of fluorescent heterocyclic aminoadamantanes as multifunctional neuroprotective agents.

Bioorganic & medicinal chemistry 20110701

Efficacy and safety of saxagliptin combination therapy in US patients with type 2 diabetes.

Postgraduate medicine 20110701

1-(Bromo-meth-yl)adamantane.

Acta crystallographica. Section E, Structure reports online 20110701

What happens to hydrophobic interactions during transfer from the solution to the gas phase? The case of electrospray-based soft ionization methods.

Journal of the American Society for Mass Spectrometry 20110701

How do aminoadamantanes block the influenza M2 channel, and how does resistance develop?

Journal of the American Chemical Society 20110629

Selectivity and mechanism of hydrogen atom transfer by an isolable imidoiron(III) complex.

Journal of the American Chemical Society 20110629

Probing multivalent host-guest interactions between modified polymer layers by direct force measurement.

The journal of physical chemistry. B 20110623

Adamantyl glycosphingolipids provide a new approach to the selective regulation of cellular glycosphingolipid metabolism.

The Journal of biological chemistry 20110617

Heteroatom-substituted analogues of orphan nuclear receptor small heterodimer partner ligand and apoptosis inducer (E)-4-[3-(1-Adamantyl)-4-hydroxyphenyl]-3-chlorocinnamic acid.

Journal of medicinal chemistry 20110609

An adamantane-based building block for DNA networks.

Chemistry, an Asian journal 20110606

Saxagliptin improves glycaemic control and is well tolerated in patients with type 2 diabetes mellitus and renal impairment.

Diabetes, obesity & metabolism 20110601

Initial combination therapy with saxagliptin and metformin provides sustained glycaemic control and is well tolerated for up to 76 weeks.

Diabetes, obesity & metabolism 20110601

The many faces of the adamantyl group in drug design.

European journal of medicinal chemistry 20110601

Adamantanes as spherical nanosondes in adducts with a chiral dirhodium complex-discriminating enantiomers and probing spatial proximities.

Magnetic resonance in chemistry : MRC 20110601

CXCR3 antagonists: quaternary ammonium salts equipped with biphenyl- and polycycloaliphatic-anchors.

Bioorganic & medicinal chemistry 20110601

Adamantane-1-ammonium acetate.

Acta crystallographica. Section E, Structure reports online 20110601

N-(Adamantan-1-yl)-2-chloro-acetamide.

Acta crystallographica. Section E, Structure reports online 20110601

Effectiveness of adding vildagliptin to the treatment of diabetic patients nonresponsive to the combination of metformin and a sulphonylurea.

Arquivos brasileiros de endocrinologia e metabologia 20110601

Place in therapy for liraglutide and saxagliptin for type 2 diabetes.

Southern medical journal 20110601

Recent diabetes issues affecting the primary care clinician.

Southern medical journal 20110601

Design, synthesis, radiolabeling, and in vitro and in vivo evaluation of bridgehead iodinated analogues of N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-N-(pyridin-2-yl)cyclohexanecarboxamide (WAY-100635) as potential SPECT ligands for the 5-HT1A receptor.

Journal of medicinal chemistry 20110526

Protein-binding molecular switches via host-guest stabilized DNA hairpins.

Journal of the American Chemical Society 20110525

Cationic supramolecular nanoparticles for co-delivery of gene and anticancer drug.

Chemical communications (Cambridge, England) 20110521

A supramolecular approach to the preparation of charge-tunable dendritic polycations for efficient gene delivery.

Chemical communications (Cambridge, England) 20110521

A versatile Fréchet-dendron compound unifies host-guest and templated heterogeneous self-assembly.

Advanced materials (Deerfield Beach, Fla.) 20110517

Identification of individual tetra- and pentacyclic naphthenic acids in oil sands process water by comprehensive two-dimensional gas chromatography/mass spectrometry.

Rapid communications in mass spectrometry : RCM 20110515

Synthesis and evaluation of carbaborane derivatives of indomethacin as cyclooxygenase inhibitors.

Bioorganic & medicinal chemistry 20110515

Regioselective bis-functionalization of endohedral dimetallofullerene, La2@C80: extremal La-La distance.

Journal of the American Chemical Society 20110511

Solid-State NMR characterization of autofluorescent fibrils formed by the elastin-derived peptide GVGVAGVG.

Biomacromolecules 20110509

Highly substituted oxabicyclic derivatives from furan: synthesis of (±)-platensimycin.

Organic letters 20110506

Enzymatic preparation of 5-hydroxy-L-proline, N-Cbz-5-hydroxy-L-proline, and N-Boc-5-hydroxy-L-proline from (α-N-protected)-L-ornithine using a transaminase or an amine oxidase.

Enzyme and microbial technology 20110506

Highly efficient, organocatalytic aerobic alcohol oxidation.

Journal of the American Chemical Society 20110504

An analysis of the impact of FDA's guidelines for addressing cardiovascular risk of drugs for type 2 diabetes on clinical development.

Contemporary clinical trials 20110501

Vildagliptin blocks vascular injury in thoracic aorta of diabetic rats by suppressing advanced glycation end product-receptor axis.

Pharmacological research 20110501

DPP-4 inhibitors: impact on glycemic control and cardiovascular risk factors.

Diabetes care 20110501

Interfacial tension of the lipid membrane formed from phosphatidylcholine-decanoic acid and phosphatidylcholine-decylamine systems.

The Journal of membrane biology 20110501

[Vildagliptin].

Nihon rinsho. Japanese journal of clinical medicine 20110501

Highly regioselective amination of unactivated alkanes by hypervalent sulfonylimino-λ³-bromane.

Science (New York, N.Y.) 20110422

Catalytic C-H bond amination from high-spin iron imido complexes.

Journal of the American Chemical Society 20110406

Inhibitory effect of N-adamantyl-3,4-dihydroxybenzamide on melanogenesis in melan-a cells and brown guinea pigs.

Archives of dermatological research 20110401

Attenuation of arthritis in rodents by a novel orally-available inhibitor of sphingosine kinase.

Inflammopharmacology 20110401

Neuropeptide FF receptor antagonist, RF9, attenuates the fever induced by central injection of LPS in mice.

Peptides 20110401

Inhibition of DPP-4 with vildagliptin improved insulin secretion in response to oral as well as 'isoglycemic' intravenous glucose without numerically changing the incretin effect in patients with type 2 diabetes.

The Journal of clinical endocrinology and metabolism 20110401

Soluble epoxide hydrolase in the generation and maintenance of high blood pressure in spontaneously hypertensive rats.

American journal of physiology. Endocrinology and metabolism 20110401

Adamantanyl-histone deacetylase inhibitor H6CAHA exhibits favorable pharmacokinetics and augments prostate cancer radiation sensitivity.

International journal of radiation oncology, biology, physics 20110401

Targeting NFĸB mediated breast cancer chemoresistance through selective inhibition of sphingosine kinase-2.

Cancer biology & therapy 20110401

Activity of OZ78 analogues against Fasciola hepatica and Echinostoma caproni.

Acta tropica 20110401

Efficacy and safety of saxagliptin in older patients with type 2 diabetes mellitus.

Current medical research and opinion 20110401

Influence of renal or hepatic impairment on the pharmacokinetics of saxagliptin.

Clinical pharmacokinetics 20110401

FDA's first active medical product surveillance eyes antidiabetic-MI link.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110401

Multivalent interactions: a hop, skip and jump.

Nature chemistry 20110401

Gradient-driven motion of multivalent ligand molecules along a surface functionalized with multiple receptors.

Nature chemistry 20110401

Dihydrogen contacts in alkanes are subtle but not faint.

Nature chemistry 20110401

Understanding the incretin effect.

The Journal of clinical endocrinology and metabolism 20110401

Safety and efficacy of saxagliptin added to thiazolidinedione over 76 weeks in patients with type 2 diabetes mellitus.

Diabetes & vascular disease research 20110401

Safety and efficacy of saxagliptin in combination with submaximal sulphonylurea versus up-titrated sulphonylurea over 76 weeks.

Diabetes & vascular disease research 20110401

6-(1-Adamant-yl)-3-(2-chloro-phen-yl)-1,2,4-triazolo[3,4-b][1,3,4]thia-diazole.

Acta crystallographica. Section E, Structure reports online 20110401

(2SR,3RS)-Methyl 2-(adamantan-1-yl)-3-phenyl-sulfonyl-3-(pyridin-2-ylsulfan-yl)propano-ate dichloro-methane hemisolvate.

Acta crystallographica. Section E, Structure reports online 20110401

Emerging role of dipeptidyl peptidase-IV (DPP-4) inhibitor vildagliptin in the management of type 2 diabetes.

The Journal of the Association of Physicians of India 20110401

Specific binding of adamantane drugs and direction of their polar amines in the pore of the influenza M2 transmembrane domain in lipid bilayers and dodecylphosphocholine micelles determined by NMR spectroscopy.

Journal of the American Chemical Society 20110330

Photogenerated cumulenic structure of adamantyl endcapped linear carbon chains: an experimental and computational investigation based on infrared spectroscopy.

The Journal of chemical physics 20110328

Platensimycin and platencin congeners from Streptomyces platensis.

Journal of natural products 20110325

Dipeptidyl peptidase IV dependent water-soluble prodrugs of highly lipophilic bicyclic nucleoside analogues.

Journal of medicinal chemistry 20110324

Structure-activity relationships of cycloalkylamide derivatives as inhibitors of the soluble epoxide hydrolase.

Journal of medicinal chemistry 20110324

Why benchmark-quality computations are needed to reproduce 1-adamantyl cation NMR chemical shifts accurately.

The journal of physical chemistry. A 20110324

Saxagliptin/metformin (kombiglyze XR) for type 2 diabetes.

The Medical letter on drugs and therapeutics 20110321

New ultrahigh affinity host-guest complexes of cucurbit[7]uril with bicyclo[2.2.2]octane and adamantane guests: thermodynamic analysis and evaluation of M2 affinity calculations.

Journal of the American Chemical Society 20110316

Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria.

Proceedings of the National Academy of Sciences of the United States of America 20110315

Dialkylamino-2,4-dihydroxybenzoic acids as easily synthesized analogues of platensimycin and platencin with comparable antibacterial properties.

Chemistry (Weinheim an der Bergstrasse, Germany) 20110314

Discovery of novel and potent orally active calcium-sensing receptor antagonists that stimulate pulselike parathyroid hormone secretion: synthesis and structure-activity relationships of tetrahydropyrazolopyrimidine derivatives.

Journal of medicinal chemistry 20110310

Semi-metallic single-component crystal of soluble La@C82 derivative with high electron mobility.

Journal of the American Chemical Society 20110302

Synthesis, structures and in vitro cytotoxicity of some cationic cis-platinum(II) complexes containing chelating thiocarbamates.

Journal of inorganic biochemistry 20110301

Current approaches to exploit actinomycetes as a source of novel natural products.

Journal of industrial microbiology & biotechnology 20110301

A small MRI contrast agent library of gadolinium(III)-encapsulated supramolecular nanoparticles for improved relaxivity and sensitivity.

Biomaterials 20110301

Inhibition of soluble epoxide hydrolase attenuates endothelial dysfunction in animal models of diabetes, obesity and hypertension.

European journal of pharmacology 20110301

Clinical evidence and mechanistic basis for vildagliptin's action when added to metformin.

Diabetes, obesity & metabolism 20110301

Synthesis and antiviral evaluation of bisnoradamantane sulfites and related compounds.

Medicinal chemistry (Shariqah (United Arab Emirates)) 20110301

Antitumor activity of sphingosine kinase 2 inhibitor ABC294640 and sorafenib in hepatocellular carcinoma xenografts.

Cancer biology & therapy 20110301

Adamantan-1-aminium p-toluene-sulfonate.

Acta crystallographica. Section E, Structure reports online 20110301

Time course of histone deacetylase 1 and acetylated H3 and H4 histones in the brain of rats treated with ladasten.

Bulletin of experimental biology and medicine 20110301

Synthesis of 1,8-di(1-adamantyl)naphthalenes as single enantiomers stable at ambient temperatures.

Chemical communications (Cambridge, England) 20110207

Water-soluble Cp ruthenium complex containing 1,3,5-triaza-7-phosphaadamantane and 8-thiotheophylline derivatives: synthesis, characterization, and antiproliferative activity.

Inorganic chemistry 20110207

Computational study of drug binding to the membrane-bound tetrameric M2 peptide bundle from influenza A virus.

Biochimica et biophysica acta 20110201

Resistance characteristics of influenza to amino-adamantyls.

Biochimica et biophysica acta 20110201

Inhibition of recombinant N-type and native high voltage-gated neuronal Ca2+ channels by AdGABA: mechanism of action studies.

Toxicology and applied pharmacology 20110201

1-(1-acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia.

Bioorganic & medicinal chemistry letters 20110201

New avian influenza virus (H5N1) in wild birds, Qinghai, China.

Emerging infectious diseases 20110201

Oseltamivir-resistant pandemic (H1N1) 2009 virus, Mexico.

Emerging infectious diseases 20110201

Prevalence of epistasis in the evolution of influenza A surface proteins.

PLoS genetics 20110201

[Adamantane resistance among seasonal influenza A viruses between January to October in Guangzhou, 2009].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20110201

Conformationally restricted GABA analogs: from rigid carbocycles to cage hydrocarbons.

Future medicinal chemistry 20110201

Incretin therapies in the management of elderly patients with type 2 diabetes mellitus.

Hospital practice (1995) 20110201

Saxagliptin. No more effective than other gliptins, but a high potential for drug interactions.

Prescrire international 20110201

1,3,5,7-Tetra-bromo-adamantane.

Acta crystallographica. Section E, Structure reports online 20110201

The DPP-4 inhibitor vildagliptin increases pancreatic beta cell mass in neonatal rats.

European journal of pharmacology 20110115

The dipeptidyl peptidase IV (CD26, EC 3.4.14.5) inhibitor vildagliptin is a potent antihyperalgesic in rats by promoting endomorphin-2 generation in the spinal cord.

European journal of pharmacology 20110110

Antiviral drugs for influenza.

The Medical letter on drugs and therapeutics 20110110

Tuning the conversion of cyclohexane into cyclohexanol/one by molecular dioxygen, protons and reducing agents at a single non-porphyrinic iron centre and chemical versatility of the tris(2-pyridylmethyl)amine TPAFe(II)Cl2 complex in mild oxidation chemistry.

Dalton transactions (Cambridge, England : 2003) 20110107

Supramolecular thermoresponsive hyperbranched polymers constructed from poly(N-isopropylacrylamide) containing one adamantyl and two β-cyclodextrin terminal moieties.

Macromolecular rapid communications 20110103

Maximal adamantyl-substituted retinoid-related molecule-induced apoptosis requires NF-κB noncanonical and canonical pathway activation.

Cell death and differentiation 20110101

Potential of Complementary and Alternative Medicine in Preventive Management of Novel H1N1 Flu (Swine Flu) Pandemic: Thwarting Potential Disasters in the Bud.

Evidence-based complementary and alternative medicine : eCAM 20110101

Structure-based and property-compliant library design of 11β-HSD1 adamantyl amide inhibitors.

Methods in molecular biology (Clifton, N.J.) 20110101

Discovery of a novel IKK-β inhibitor by ligand-based virtual screening techniques.

Bioorganic & medicinal chemistry letters 20110101

Synthesis and 11β hydroxysteroid dehydrogenase 1 inhibition of thiazolidine derivatives with an adamantyl group.

Bioorganic & medicinal chemistry letters 20110101

Clinical experience with vildagliptin in the management of type 2 diabetes in a patient population ≥75 years: a pooled analysis from a database of clinical trials.

Diabetes, obesity & metabolism 20110101

Molecular and structural determinants of adamantyl susceptibility to HLA-DRs allelic variants: an in silico approach to understand the mechanism of MLEs.

Journal of computer-aided molecular design 20110101

On the mechanisms of bananin activity against severe acute respiratory syndrome coronavirus.

The FEBS journal 20110101

Emerging influenza antiviral resistance threats.

The Journal of infectious diseases 20110101

Dual resistance to adamantanes and oseltamivir among seasonal influenza A(H1N1) viruses: 2008-2010.

The Journal of infectious diseases 20110101

Focus on incretin-based therapies: targeting the core defects of type 2 diabetes.

Postgraduate medicine 20110101

Anti-amnesic and neuroprotective actions of the sigma-1 receptor agonist (-)-MR22 in rats with selective cholinergic lesion and amyloid infusion.

Journal of Alzheimer's disease : JAD 20110101

Vildagliptin-induced acute pancreatitis.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20110101

Comments on the article 'Effects of vildagliptin twice daily vs. sitagliptin once daily on 24-hour acute glucose fluctuations' by Marfella et al.: (Journal of Diabetes and Its Complications 24 [2010] 79-83).

Journal of diabetes and its complications 20110101

Experimental osteoarthritis in rats is attenuated by ABC294640, a selective inhibitor of sphingosine kinase-2.

Pharmacology 20110101

Public health interventions for epidemics: implications for multiple infection waves.

BMC public health 20110101

Assessing the general safety and tolerability of vildagliptin: value of pooled analyses from a large safety database versus evaluation of individual studies.

Vascular health and risk management 20110101

Caffeoylquinic acids are major constituents with potent anti-influenza effects in brazilian green propolis water extract.

Evidence-based complementary and alternative medicine : eCAM 20110101

[Ladasten in the management of non-motor symptoms of Parkinson's disease].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101

[Plasmapheresis as treatment for severe hypertriglyceridemia].

Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20110101

[A comparative study of hemantane and amantadine effects on dopamine transporter expression in brain of normal and MPTP-treated C57BL/6 mice].

Eksperimental'naia i klinicheskaia farmakologiia 20110101

A novel disulfide-rich protein motif from avian eggshell membranes.

PloS one 20110101

Reassortment and mutations associated with emergence and spread of oseltamivir-resistant seasonal influenza A/H1N1 viruses in 2005-2009.

PloS one 20110101

In Vitro Gene Delivery Mediated by Asialofetuin-Appended Cationic Liposomes Associated with γ-Cyclodextrin into Hepatocytes.

Journal of drug delivery 20110101

4-[(1-Adamant-yl)carbamo-yl]pyridinium chloride.

Acta crystallographica. Section E, Structure reports online 20110101

Correlation of the rates of solvolysis of neopentyl chloroformate-a recommended protecting agent.

International journal of molecular sciences 20110101

Accelerated retinal ganglion cell death in mice deficient in the Sigma-1 receptor.

Molecular vision 20110101

[New adamantane derivatives and ways of overcoming the resistance of influenza A viruses to rimantadine and amantadine].

Voprosy virusologii 20110101

Fibrous architectures and organogels of tris(phenylethynylphenyl)adamantane molecules with amino acid moieties: their solvato-controlled helicity induction.

Chirality 20110101

Effect of enhanced glycemic control with saxagliptin on endothelial nitric oxide release and CD40 levels in obese rats.

Journal of atherosclerosis and thrombosis 20110101

Antidepressant potential of nitrogen-containing heterocyclic moieties: An updated review.

Journal of pharmacy & bioallied sciences 20110101

Incretin-based therapy and pancreatitis-what is the risk?

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20110101

Genomic and protein structural maps of adaptive evolution of human influenza A virus to increased virulence in the mouse.

PloS one 20110101

New respiratory viruses and the elderly.

The open respiratory medicine journal 20110101

Reply to the 'Comments on the article 'Effects of vildagliptin twice daily vs. sitagliptin once daily on 24-hour acute glucose fluctuations'', by Avogaro (Journal of Diabetes and Its Complications 25 [2011] 352-353).

Journal of diabetes and its complications 20110101

[Influence of hemantane and doxycycline on MPTP-evoked behavior violations in C57BL/6 mice].

Eksperimental'naia i klinicheskaia farmakologiia 20110101

Bioequivalence of saxagliptin/metformin extended-release (XR) fixed-dose combination tablets and single-component saxagliptin and metformin XR tablets in healthy adult subjects.

Clinical drug investigation 20110101

Comparative efficacy of vildagliptin and sitagliptin in Japanese patients with type 2 diabetes mellitus: a matching-adjusted indirect comparison of randomized trials.

Clinical drug investigation 20110101

Rapid detection and subtyping of human influenza A viruses and reassortants by pyrosequencing.

PloS one 20110101

[Comparative study of amantadine and hemantane effects on development of levodopa-induced dyskinesia in rat model of parkinsonian syndrome].

Eksperimental'naia i klinicheskaia farmakologiia 20110101

Glycosphingolipids and insulin resistance.

Advances in experimental medicine and biology 20110101

Hyperbranched polyethylenimine bearing cyclodextrin moieties showing temperature and pH controlled dye release.

Beilstein journal of organic chemistry 20110101

The dipeptidyl peptidase-4 (DPP-4) inhibitor vildagliptin improves glycemic control in type 2 diabetic patients undergoing hemodialysis.

Endocrine journal 20110101

Assessment of the antiviral properties of recombinant porcine SP-D against various influenza A viruses in vitro.

PloS one 20110101

Solvolyses of benzoyl chlorides in weakly nucleophilic media.

International journal of molecular sciences 20110101

Early and late effects of the DPP-4 inhibitor vildagliptin in a rat model of post-myocardial infarction heart failure.

Cardiovascular diabetology 20110101

Calcium-permeable AMPA receptors in the retina.

Frontiers in molecular neuroscience 20110101

Molecular evolution of the H6 subtype influenza A viruses from poultry in eastern China from 2002 to 2010.

Virology journal 20110101

Effects of alkaline or liquid-ammonia treatment on crystalline cellulose: changes in crystalline structure and effects on enzymatic digestibility.

Biotechnology for biofuels 20110101

9-Azanoradamantane N-oxyl (Nor-AZADO): a highly active organocatalyst for alcohol oxidation.

Chemical & pharmaceutical bulletin 20110101

Molecular epidemiology of influenza A/H3N2 viruses circulating in Uganda.

PloS one 20110101

[Investigation of antiviral activity of adamantan boron derivaties on pandemic influenza virus models].

Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20110101

A supramolecular sensing platform for phosphate anions and an anthrax biomarker in a microfluidic device.

International journal of molecular sciences 20110101

Correlation of the rates of solvolysis of i-butyl fluoroformate and a consideration of leaving-group effects.

International journal of molecular sciences 20110101

[Analysis of the binding capacity of the benzodiazepine site of gabaa receptor in mice C57BL/6 and BALB/C pretreated with anxiolytics].

Eksperimental'naia i klinicheskaia farmakologiia 20110101

Influenza A(H1N1) Oseltamivir Resistant Viruses in the Netherlands During the Winter 2007/2008.

The open virology journal 20110101

[Effect of antiasthenic drug ladasten on the level of cytokines and behavior in experimental model of anxious depression in C57BL/6 male mice].

Eksperimental'naia i klinicheskaia farmakologiia 20110101

[Self-evaluation of single test doses and objective indices of ladasten vs. placebo efficacy in neurasthenic patients].

Eksperimental'naia i klinicheskaia farmakologiia 20110101

[Pharmacokinetics of hemantane in rats].

Eksperimental'naia i klinicheskaia farmakologiia 20110101

[Present and future in the use of anti-tubercular drugs].

Pneumologia (Bucharest, Romania) 20110101

[Characterization of patients with type 2 diabetes treated with vildagliptin].

Acta medica portuguesa 20110101

Schizophrenia: a pathogenetic autoimmune disease caused by viruses and pathogens and dependent on genes.

Journal of pathogens 20110101

Homoleptic diphosphacyclobutadiene complexes [M(η(4)-P2C2R2)2]x- (M = Fe, Co; x = 0, 1).

Chemistry (Weinheim an der Bergstrasse, Germany) 20101227

Concise formal total synthesis of platensimycin mediated by a stereoselective autoxidation and hydroxyl group directed conjugative reduction.

Organic letters 20101217

Pressure perturbation calorimetry and the thermodynamics of noncovalent interactions in water: comparison of protein-protein, protein-ligand, and cyclodextrin-adamantane complexes.

The journal of physical chemistry. B 20101216

Synthesis and structure-activity relationship of tetrahydropyrazolopyrimidine derivatives--a novel structural class of potent calcium-sensing receptor antagonists.

Bioorganic & medicinal chemistry 20101215

Nanoparticle vesicles through self assembly of cyclodextrin- and adamantyl-modified silica.

Macromolecular rapid communications 20101215

A bismuth(III)-catalyzed Friedel-Crafts cyclization and stereocontrolled organocatalytic approach to (-)-platensimycin.

Organic letters 20101203

Drugs in development for tuberculosis.

Drugs 20101203

Comparative embryotoxicity of different antimalarial peroxides: in vitro study using the rat whole embryo culture model (WEC).

Reproductive toxicology (Elmsford, N.Y.) 20101201

Influence of an additional amino group on the potency of aminoadamantanes against influenza virus A. II - Synthesis of spiropiperazines and in vitro activity against influenza A H3N2 virus.

Bioorganic chemistry 20101201

Tuning hydrophobicity of highly cationic tetradecameric Gramicidin S analogues using adamantane amino acids.

Bioorganic & medicinal chemistry 20101201

Electrophysiological analysis of the inhibitory effects of FMRFamide-like peptides on the pacemaker activity of gonadotropin-releasing hormone neurons.

Journal of neurophysiology 20101201

Voltage-dependent and -independent block of α-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor channels.

Journal of neurochemistry 20101201

(2,2'-Bipyridine-κN,N')[2-tert-butyl-anilinato(2-)]dichloridooxido-molybdenum(VI) dichloro-methane hemisolvate.

Acta crystallographica. Section E, Structure reports online 20101201

6-(Adamantan-1-yl)-3-(3-fluoro-phen-yl)-1,2,4-triazolo[3,4-b][1,3,4]thia-diazole.

Acta crystallographica. Section E, Structure reports online 20101201

1-Adamantylmethyl 2-amino-benzoate.

Acta crystallographica. Section E, Structure reports online 20101201

(1-Adamant-yl)(2-methyl-phen-yl)methanone.

Acta crystallographica. Section E, Structure reports online 20101201

Computation of deuterium isotope perturbation of 13C NMR chemical shifts of alkanes: a local mode zero-point level approach.

The journal of physical chemistry. A 20101125

Osmotic stress regulates the strength and kinetics of sugar binding to the maltoporin channel.

Journal of physics. Condensed matter : an Institute of Physics journal 20101117

β-cyclodextrin as the vehicle for forming ratiometric mercury ion sensor usable in aqueous media, biological fluids, and live cells.

Langmuir : the ACS journal of surfaces and colloids 20101116

Discovery and optimization of adamantyl carbamate inhibitors of 11β-HSD1.

Bioorganic & medicinal chemistry letters 20101115

Vildagliptin: a review of its use in type 2 diabetes mellitus.

Drugs 20101112

Structural, electronic, and vibrational properties of amino-adamantane and rimantadine isomers.

The journal of physical chemistry. A 20101111

Pyridoindole derivative as electron transporting host material for efficient deep-blue phosphorescent organic light-emitting diodes.

Advanced materials (Deerfield Beach, Fla.) 20101109

Safety and tolerability of vildagliptin vs. thiazolidinedione as add-on to metformin in type 2 diabetic patients with and without mild renal impairment: a retrospective analysis of the GALIANT study.

Diabetes research and clinical practice 20101101

DPP-4 inhibitors: what may be the clinical differentiators?

Diabetes research and clinical practice 20101101

Multidrug therapy in a patient with Rabson-Mendenhall syndrome.

Diabetologia 20101101

Influenza antiviral prescribing practices during the 2007-08 and 2008-09 influenza seasons in the setting of increased resistance to oseltamivir among circulating influenza viruses.

Antiviral research 20101101

Design and synthesis of bioactive adamantanaminoalcohols and adamantanamines.

European journal of medicinal chemistry 20101101

Saxagliptin is non-inferior to glipizide in patients with type 2 diabetes mellitus inadequately controlled on metformin alone: a 52-week randomised controlled trial.

International journal of clinical practice 20101101

Observation of NMR noise from solid samples.

Journal of magnetic resonance (San Diego, Calif. : 1997) 20101101

Antiestrogenic effects of the novel sphingosine kinase-2 inhibitor ABC294640.

Endocrinology 20101101

Influenza 2010-2011: lessons from the 2009 pandemic.

Cleveland Clinic journal of medicine 20101101

Adamantyl-substituted retinoid-related molecules induce apoptosis in human acute myelogenous leukemia cells.

Molecular cancer therapeutics 20101101

[Preclinical and clinical findings of the dipeptidyl peptidase-4 inhibitor vildagliptin].

Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20101101

Proteomic analysis and identification of ladasten target proteins in rat brain.

Bulletin of experimental biology and medicine 20101101

Prone position ventilation, recruitment maneuver and intravenous zanamivir in severe refractory hypoxemia caused by influenza A (H1N1).

Clinics (Sao Paulo, Brazil) 20101101

[Effects of subchronic hemantane administration on dopamine and serotonin receptors in intact and MPP+-treated rat brain ex vivo].

Eksperimental'naia i klinicheskaia farmakologiia 20101101

1,3-Bis(1-adamant-yl)imidazolium tetra-chloridoferrate(III).

Acta crystallographica. Section E, Structure reports online 20101101

Efficacy, safety and pharmacokinetics of 1,2,4-trioxolane OZ78 against an experimental infection with Fasciola hepatica in sheep.

Veterinary parasitology 20101029

An adamantyl amino acid containing gramicidin S analogue with broad spectrum antibacterial activity and reduced hemolytic activity.

Chemistry (Weinheim an der Bergstrasse, Germany) 20101025

Development and validation of a liquid chromatography/mass spectrometry method for pharmacokinetic studies of OZ78, a fasciocidal drug candidate.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101015

Facile fabrication of narrowly-distributed polymeric micelles via host-guest inclusion complexation of hyperbranched polymers and cyclodextrin and its two-dimensional self-assembly.

Physical chemistry chemical physics : PCCP 20101014

1-Aryl-3-(1-acylpiperidin-4-yl)urea inhibitors of human and murine soluble epoxide hydrolase: structure-activity relationships, pharmacokinetics, and reduction of inflammatory pain.

Journal of medicinal chemistry 20101014

Rigid adamantane tripod linkage for well-defined conductance of a single-molecule junction.

Physical chemistry chemical physics : PCCP 20101007

Catalytic enantioselective alkylative dearomatization-annulation: total synthesis and absolute configuration assignment of hyperibone K.

Journal of the American Chemical Society 20101006

An oxidative Prins-pinacol tandem process and its application to the synthesis of (-)-platensimycin.

Chemistry (Weinheim an der Bergstrasse, Germany) 20101004

Effect of a high-fat meal on the pharmacokinetics of saxagliptin in healthy subjects.

Journal of clinical pharmacology 20101001

Opposite control of body temperature by NPFF1 and NPFF2 receptors in mice.

Neuropeptides 20101001

LW6, a novel HIF-1 inhibitor, promotes proteasomal degradation of HIF-1alpha via upregulation of VHL in a colon cancer cell line.

Biochemical pharmacology 20101001

Suppression of colitis-driven colon cancer in mice by a novel small molecule inhibitor of sphingosine kinase.

Carcinogenesis 20101001

Pharmacokinetics of lipoyl vildagliptin, a novel dipeptidyl peptidase IV inhibitor after oral administration in rats.

Xenobiotica; the fate of foreign compounds in biological systems 20101001

Antivirals for influenza: strategies for use in pediatrics.

Paediatric drugs 20101001

Saxagliptin and metformin XR combination therapy provides glycemic control over 24 hours in patients with T2DM inadequately controlled with metformin.

Current medical research and opinion 20101001

Efficacy and safety of saxagliptin in combination with metformin compared with sitagliptin in combination with metformin in adult patients with type 2 diabetes mellitus.

Diabetes/metabolism research and reviews 20101001

Antiretroviral activity of two polyisoprenylated acylphloroglucinols, 7-epi-nemorosone and plukenetione A, isolated from Caribbean propolis.

International journal of clinical pharmacology and therapeutics 20101001

1,3,5-Triaza-adamantan-7-amine.

Acta crystallographica. Section E, Structure reports online 20101001

Neuraminidase inhibitor susceptibility testing in human influenza viruses: a laboratory surveillance perspective.

Viruses 20101001

Synthesis of dibenzo[b,f][1,4]oxazepin-11(10H)-ones via intramolecular cyclocarbonylation reactions using PdI(2)/Cytop 292 as the catalytic system.

The Journal of organic chemistry 20100917

Saxagliptin: a dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes mellitus.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100915

Design and construction of an organic crystal with a novel interpenetrated n-Borromean linked topology.

Chemical communications (Cambridge, England) 20100914

[Fe(III)(F(20)-tpp)Cl] is an effective catalyst for nitrene transfer reactions and amination of saturated hydrocarbons with sulfonyl and aryl azides as nitrogen source under thermal and microwave-assisted conditions.

Chemistry (Weinheim an der Bergstrasse, Germany) 20100910

Effect of artemether, artesunate, OZ78, praziquantel, and tribendimidine alone or in combination chemotherapy on the tegument of Clonorchis sinensis.

Parasitology international 20100901

Efficacy and tolerability of vildagliptin as an add-on to glimepiride in Japanese patients with Type 2 diabetes mellitus.

Diabetes research and clinical practice 20100901

Combination therapy with nateglinide and vildagliptin improves postprandial metabolic derangements in Zucker fatty rats.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20100901

Vildagliptin add-on to metformin produces similar efficacy and reduced hypoglycaemic risk compared with glimepiride, with no weight gain: results from a 2-year study.

Diabetes, obesity & metabolism 20100901

Dipeptidylpeptidase-4 inhibitors (gliptins): focus on drug-drug interactions.

Clinical pharmacokinetics 20100901

Distinguishing among incretin-based therapies. Glucose-lowering effects of incretin-based therapies.

The Journal of family practice 20100901

Distinguishing among incretin-based therapies. Safety, tolerability, and nonglycemic effects of incretin-based therapies.

The Journal of family practice 20100901

Distinguishing among incretin-based therapies. Patient education and self-management.

The Journal of family practice 20100901

Distinguishing among incretin-based therapies. Introduction.

The Journal of family practice 20100901

Distinguishing among incretin-based therapies. Pathophysiology of type 2 diabetes mellitus: potential role of incretin-based therapies.

The Journal of family practice 20100901

Pharmacokinetics and pharmacodynamics of vildagliptin in Japanese patients with type 2 diabetes.

International journal of clinical pharmacology and therapeutics 20100901

[Saxagliptin (Onglyza): new inhibitor of the dipeptidylpeptidase-4 for the oral treatment of type 2 diabetes].

Revue medicale de Liege 20100901

Convergence in the evolution of nanodiamond Raman spectra with particle size: a theoretical investigation.

ACS nano 20100824

Proof of RNA interference in humans after systemic delivery of siRNAs.

Angewandte Chemie (International ed. in English) 20100823

Memantine preferentially blocks extrasynaptic over synaptic NMDA receptor currents in hippocampal autapses.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20100818

Heteroadamantyl cannabinoids.

Journal of medicinal chemistry 20100812

Reactions of aromatic N-heterocycles with a lutetium benzyl complex supported by a ferrocene-diamide ligand.

Dalton transactions (Cambridge, England : 2003) 20100807

Duplex of capped-cyclodextrins, synthesis and cross-linking behaviour with a biopolymer.

Organic & biomolecular chemistry 20100807

Neurotrophic peptides incorporating adamantane improve learning and memory, promote neurogenesis and synaptic plasticity in mice.

FEBS letters 20100804

Formation and rearrangement of Sn(II) phosphanediide cages.

Chemistry (Weinheim an der Bergstrasse, Germany) 20100802

A supramolecular bifunctional artificial enzyme with superoxide dismutase and glutathione peroxidase activities.

Bioorganic chemistry 20100801

Effects of one year treatment of vildagliptin added to pioglitazone or glimepiride in poorly controlled type 2 diabetic patients.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20100801

Managing type 2 diabetes in the primary care setting: beyond glucocentricity.

The American journal of the medical sciences 20100801

Pharmacokinetics of dipeptidylpeptidase-4 inhibitors.

Diabetes, obesity & metabolism 20100801

Efficacy and safety of vildagliptin and voglibose in Japanese patients with type 2 diabetes: a 12-week, randomized, double-blind, active-controlled study.

Diabetes, obesity & metabolism 20100801

Saxagliptin efficacy.

Diabetes, obesity & metabolism 20100801

Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors.

Bioorganic & medicinal chemistry letters 20100801

Incretin-based therapies in the management of type 2 diabetes: rationale and reality in a managed care setting.

The American journal of managed care 20100801

N'-[(2-n-Butyl-4-chloro-1H-imidazol-5-yl)-methyl-idene]adamantane-1-carbo-hydrazide sesquihydrate ethanol hemi-solvate.

Acta crystallographica. Section E, Structure reports online 20100801

2-(1-Adamant-yl)-1,3-diphenyl-propan-2-ol.

Acta crystallographica. Section E, Structure reports online 20100801

Nanosieving of anions and cavity-size-dependent association of cyclodextrins on a 1-adamantanethiol self-assembled monolayer.

ACS nano 20100727

Molecular recognition of vesicles: host-guest interactions combined with specific dimerization of zwitterions.

Chemistry (Weinheim an der Bergstrasse, Germany) 20100726

Syntheses, crystal structures and magnetic properties of a novel family of penta-manganese complexes derived from an assembly system containing polydentate hydroxy-rich Schiff-base ligands.

Dalton transactions (Cambridge, England : 2003) 20100721

Adsorption of Cu2+ on spherical Fe-MCM-41 and its application for oxidation of adamantane.

Journal of hazardous materials 20100715

Interaction of aminoadamantane derivatives with the influenza A virus M2 channel-docking using a pore blocking model.

Bioorganic & medicinal chemistry letters 20100715

Spectroscopic study of the authentic emitter of AMPPD chemiluminescence in alkaline aqueous solution.

Physical chemistry chemical physics : PCCP 20100707

Four-coordinate iridium(I) monohydrides: reversible dinitrogen binding, bond activations, and deprotonations.

Journal of the American Chemical Society 20100707

Discovery of adamantyl ethanone derivatives as potent 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) inhibitors.

ChemMedChem 20100705

Three-coordinate terminal imidoiron(III) complexes: structure, spectroscopy, and mechanism of formation.

Inorganic chemistry 20100705

Syntheses and crystal structures of a series of coordination polymers constructed from C2-symmetric ligand 1,3-adamantanedicarboxylic acid.

Chemistry, an Asian journal 20100705

Spectroscopic and electron-transfer reactivity studies of bulky bis(N-cycloalkyl-3,5-tBu2-salicylaldiminato)copper(II) complexes: generation of uncoordinated and coordinated phenoxyl radicals.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100701

In vitro interactions between new antitubercular drug candidates SQ109 and TMC207.

Antimicrobial agents and chemotherapy 20100701

Saxagliptin: a new drug for the treatment of type 2 diabetes.

Mini reviews in medicinal chemistry 20100701

Modulation by salt intake of the vascular response mediated through adenosine A(2A) receptor: role of CYP epoxygenase and soluble epoxide hydrolase.

American journal of physiology. Regulatory, integrative and comparative physiology 20100701

Role of vildagliptin in managing type 2 diabetes mellitus in the elderly.

Current medical research and opinion 20100701

Glucagon-like peptide 1 prevents reactive oxygen species-induced endothelial cell senescence through the activation of protein kinase A.

Arteriosclerosis, thrombosis, and vascular biology 20100701

Calcium-permeable AMPA receptors are involved in the induction and expression of l-DOPA-induced dyskinesia in Parkinson's disease.

Journal of neurochemistry 20100701

Current development and future prospects in chemotherapy of tuberculosis.

Respirology (Carlton, Vic.) 20100701

Hormonal and metabolic effects of morning or evening dosing of the dipeptidyl peptidase IV inhibitor vildagliptin in patients with type 2 diabetes.

British journal of clinical pharmacology 20100701

Incretin physiology and its role in type 2 diabetes mellitus.

The Journal of the American Osteopathic Association 20100701

Newer agents for blood glucose control in type 2 diabetes: systematic review and economic evaluation.

Health technology assessment (Winchester, England) 20100701

(1-Adamant-yl)diphenyl-methano-l.

Acta crystallographica. Section E, Structure reports online 20100701

1,3,5,7-Tetra-kis(4-iodo-phen-yl)adamantane benzene tetra-solvate.

Acta crystallographica. Section E, Structure reports online 20100701

1-(2-Phenyl-eth-yl)adamantane.

Acta crystallographica. Section E, Structure reports online 20100701

3-(1-Adamant-yl)-1-{[4-(2-meth-oxy-phen-yl)piperazin-1-yl]meth-yl}-4-methyl-1H-1,2,4-triazole-5(4H)-thione.

Acta crystallographica. Section E, Structure reports online 20100701

Iron-catalyzed halogenation of alkanes: modeling of nonheme halogenases by experiment and DFT calculations.

Chemistry (Weinheim an der Bergstrasse, Germany) 20100625

Pharmacokinetic screening of soluble epoxide hydrolase inhibitors in dogs.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100614

Dimeric capsules formed by tetra-CMPO derivatives of (thia)calix[4]arenes.

Chemistry, an Asian journal 20100601

Saxagliptin: a new dipeptidyl peptidase 4 inhibitor for type 2 diabetes.

The Annals of pharmacotherapy 20100601

Bioconversion of 1-adamantanol to 1,3-adamantanediol using Streptomyces sp. SA8 oxidation system.

Journal of bioscience and bioengineering 20100601

Assembly of a metal-organic framework by sextuple intercatenation of discrete adamantane-like cages.

Nature chemistry 20100601

Assessing the cardio-cerebrovascular safety of vildagliptin: meta-analysis of adjudicated events from a large Phase III type 2 diabetes population.

Diabetes, obesity & metabolism 20100601

An assessment of adverse effects of vildagliptin versus comparators on the liver, the pancreas, the immune system, the skin and in patients with impaired renal function from a large pooled database of Phase II and III clinical trials.

Diabetes, obesity & metabolism 20100601

(3aRS,4SR,7RS,7aSR)-2-(Tricyclo-[3.3.1.1]decan-1-yl)-4,5,6,7-tetra-hydro-4,7-epoxy-isoindoline-1,3-dione.

Acta crystallographica. Section E, Structure reports online 20100601

Structure-activity relationship of an ozonide carboxylic acid (OZ78) against Fasciola hepatica.

Journal of medicinal chemistry 20100527

A 'clickable' hybrid nanocluster of cubic symmetry.

Chemistry (Weinheim an der Bergstrasse, Germany) 20100517

Mixed infections of pandemic H1N1 and seasonal H3N2 viruses in 1 outbreak.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20100515

Surface modification of cellulose fiber via supramolecular assembly of biodegradable polyesters by the aid of host-guest inclusion complexation.

Biomacromolecules 20100510

Metal oxide-organic frameworks (MOOFs), a new series of coordination hybrids constructed from molybdenum(VI) oxide and bitopic 1,2,4-triazole linkers.

Dalton transactions (Cambridge, England : 2003) 20100507

Efficient preparation of photoswitchable dithienylethene-linker-conjugates by palladium-catalyzed coupling reactions of terminal alkynes with thienyl chlorides and other aryl halides.

Chemistry, an Asian journal 20100503

Synthesis and evaluation of SQ109 analogues as potential anti-tuberculosis candidates.

European journal of medicinal chemistry 20100501

Inhibition of glycosphingolipid synthesis induces a profound reduction of plasma cholesterol and inhibits atherosclerosis development in APOE*3 Leiden and low-density lipoprotein receptor-/- mice.

Arteriosclerosis, thrombosis, and vascular biology 20100501

A novel sphingosine kinase inhibitor induces autophagy in tumor cells.

The Journal of pharmacology and experimental therapeutics 20100501

Soluble epoxide hydrolase deficiency attenuates neointima formation in the femoral cuff model of hyperlipidemic mice.

Arteriosclerosis, thrombosis, and vascular biology 20100501

Double (V27A/S31N) mutant 2009 pandemic influenza A (H1N1) virus isolated from adamantane non-treated inmunocompetent child.

Diagnostic microbiology and infectious disease 20100501

The development and SAR of pyrrolidine carboxamide 11beta-HSD1 inhibitors.

Bioorganic & medicinal chemistry letters 20100501

Graphic rule for drug metabolism systems.

Current drug metabolism 20100501

A systematic assessment of cardiovascular outcomes in the saxagliptin drug development program for type 2 diabetes.

Postgraduate medicine 20100501

Choosing among the incretin agents and why it matters.

The Journal of family practice 20100501

NMR-based structural modeling of graphite oxide using multidimensional 13C solid-state NMR and ab initio chemical shift calculations.

Journal of the American Chemical Society 20100428

A promising approach to the synthesis of 3D nanoporous graphitic carbon as a unique electrocatalyst support for methanol oxidation.

ChemSusChem 20100426

Imino-bridged bisphosphaalkenes (2,4-diphospha-3-azapentadienes).

Chemistry (Weinheim an der Bergstrasse, Germany) 20100426

[New hypoglycemic agents in type 2 diabetes].

La Revue du praticien 20100420

An extended cavitand with an introverted carboxylic acid.

Chemical communications (Cambridge, England) 20100414

Highly efficient dimerization of ethylene by (imido)vanadium complexes containing (2-anilidomethyl)pyridine ligands: notable ligand effect toward activity and selectivity.

Journal of the American Chemical Society 20100407

Searching for intermediates in Prins cyclisations: the 2-oxa-5-adamantyl carbocation.

Organic & biomolecular chemistry 20100407

Computational structure-activity study directs synthesis of novel antitumor enkephalin analogs.

Amino acids 20100401

Emergence of H5N1 avian influenza viruses with reduced sensitivity to neuraminidase inhibitors and novel reassortants in Lao People's Democratic Republic.

The Journal of general virology 20100401

Changes in prandial glucagon levels after a 2-year treatment with vildagliptin or glimepiride in patients with type 2 diabetes inadequately controlled with metformin monotherapy.

Diabetes care 20100401

Self-refocused slice selection by magic echo DANTE with 270 degrees flipping Gaussian RF modulation.

Journal of magnetic resonance (San Diego, Calif. : 1997) 20100401

Efficacy of a novel sphingosine kinase inhibitor in experimental Crohn's disease.

Inflammopharmacology 20100401

Characterization of the potent gonadotropin-releasing activity of RF9, a selective antagonist of RF-amide-related peptides and neuropeptide FF receptors: physiological and pharmacological implications.

Endocrinology 20100401

7-Phenylplatensimycin and 11-methyl-7-phenylplatensimycin: more potent analogs of platensimycin.

Bioorganic & medicinal chemistry letters 20100401

Discovery and syntheses of 'superbug challengers'-platensimycin and platencin.

Chemistry, an Asian journal 20100401

Oseltamivir in seasonal influenza: cumulative experience in low- and high-risk patients.

The Journal of antimicrobial chemotherapy 20100401

Isolation, structure and biological activities of platencin A(2)-A(4) from Streptomyces platensis.

Bioorganic & medicinal chemistry 20100401

In vitro reconstitution of SARS-coronavirus mRNA cap methylation.

PLoS pathogens 20100401

Electronic and geometric effects of phosphatriazaadamantane ligands on the catalytic activity of an [FeFe] hydrogenase inspired complex.

Dalton transactions (Cambridge, England : 2003) 20100328

Cationic heteroleptic cyclometalated iridium(III) complexes containing phenyl-triazole and triazole-pyridine clicked ligands.

Molecules (Basel, Switzerland) 20100323

Cyclodextrin supramolecular complex as a water-soluble ratiometric sensor for ferric ion sensing.

Langmuir : the ACS journal of surfaces and colloids 20100316

A neurotensin agonist and antagonist decrease and increase activity, respectively, but do not preclude discrete cue conditioning.

Journal of psychopharmacology (Oxford, England) 20100301

ASP4000, a slow-binding dipeptidyl peptidase 4 inhibitor, has antihyperglycemic activity of long duration in Zucker fatty rats.

Acta diabetologica 20100301

Sensitization of ovarian carcinoma cells to the atypical retinoid ST1926 by the histone deacetylase inhibitor, RC307: enhanced DNA damage response.

International journal of cancer 20100301

Structural characterization of human heme oxygenase-1 in complex with azole-based inhibitors.

Journal of inorganic biochemistry 20100301

Safety of oseltamivir compared with the adamantanes in children less than 12 months of age.

The Pediatric infectious disease journal 20100301

Improvement of secondary metabolite production in Streptomyces by manipulating pathway regulation.

Applied microbiology and biotechnology 20100301

Sugar-decorated sugar vesicles: lectin-carbohydrate recognition at the surface of cyclodextrin vesicles.

Chemistry (Weinheim an der Bergstrasse, Germany) 20100301

Synthesis and antiproliferative evaluation of certain indolo[3,2-c]quinoline derivatives.

Bioorganic & medicinal chemistry 20100301

[DPP-4 inhibitors in clinical use. Therapy without the risk of hypoglycaemia].

Pharmazie in unserer Zeit 20100301

Rare influenza A (H3N2) variants with reduced sensitivity to antiviral drugs.

Emerging infectious diseases 20100301

Qualitative GC-MS assessment of TCP and TAMORF elimination in rats.

Arhiv za higijenu rada i toksikologiju 20100301

The physiologic role of incretin hormones: clinical applications.

The Journal of the American Osteopathic Association 20100301

[Neurochemical study of effects of the new anxiolytic drugs afobazol and ladasten on the synthesis and metabolism of monoamines and their metabolites in the brain structures of Wistar rat on the model of monoamine synthesis blockade induced by aromatic amino acid decarboxylase inhibitor NSD-1015].

Eksperimental'naia i klinicheskaia farmakologiia 20100301

A comparison of efficacy and safety of vildagliptin and gliclazide in combination with metformin in patients with Type 2 diabetes inadequately controlled with metformin alone: a 52-week, randomized study.

Diabetic medicine : a journal of the British Diabetic Association 20100301

Flu channel drug resistance: a tale of two sites.

Protein & cell 20100301

Adamantyl-functionalized polymer monolith for capillary electrochromatography.

Journal of chromatography. A 20100226

Liraglutide, but not vildagliptin, restores normoglycaemia and insulin content in the animal model of type 2 diabetes, Psammomys obesus.

Regulatory peptides 20100225

Single-electron self-exchange between cage hydrocarbons and their radical cations in the gas phase.

Chemphyschem : a European journal of chemical physics and physical chemistry 20100222

Study of branched cationic beta-cyclodextrin polymer/indomethacin complex and its release profile from alginate hydrogel.

International journal of pharmaceutics 20100215

Regioselective exohedral functionalization of La@C82 and its 1,2,3,4,5-pentamethylcyclopentadiene and adamantylidene adducts.

Chemistry (Weinheim an der Bergstrasse, Germany) 20100215

Quinolinotriazole-beta-cyclodextrin and its adamantanecarboxylic acid complex as efficient water-soluble fluorescent Cd(2+) sensors.

Bioorganic & medicinal chemistry 20100215

Conjugates of desferrioxamine B (DFOB) with derivatives of adamantane or with orally available chelators as potential agents for treating iron overload.

Journal of medicinal chemistry 20100211

Ca2+-permeable AMPA receptors mediate induction of test pulse depression of naive synapses in rat visual cortical slices at early postnatal stage.

Neuroscience 20100203

Tailoring Polymeric Hydrogels through Cyclodextrin Host-Guest Complexation.

Macromolecular rapid communications 20100202

Pharmacological characterization of the mouse NPFF2 receptor.

Peptides 20100201

Medicinal Chemistry of Incretin Mimetics and DPP-4 Inhibitors.

ChemMedChem 20100201

Efficacy of a new peracetic acid-based disinfectant agent ('Adaspor ready to use').

The Journal of hospital infection 20100201

Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity.

Cancer research 20100201

Enhancing tumor vaccines: catalyzing MHC class II peptide exchange.

Expert review of vaccines 20100201

Efficacy of the new neuraminidase inhibitor CS-8958 against H5N1 influenza viruses.

PLoS pathogens 20100201

[Role of the brain dopaminergic and serotoninergic systems in psychopharmacological effects of ladasten and sydnocarb].

Eksperimental'naia i klinicheskaia farmakologiia 20100201

Saxagliptin in type 2 diabetes.

Drugs of today (Barcelona, Spain : 1998) 20100201

Application of the dipeptidyl peptidase IV (DPPIV/CD26) based prodrug approach to different amine-containing drugs.

Journal of medicinal chemistry 20100128

Novel KCNQ2/Q3 agonists as potential therapeutics for epilepsy and neuropathic pain.

Journal of medicinal chemistry 20100128

Fabrication and luminescence of designer surface patterns with beta-cyclodextrin functionalized quantum dots via multivalent supramolecular coupling.

ACS nano 20100126

Spatially controllable DNA condensation by a water-soluble supramolecular hybrid of single-walled carbon nanotubes and beta-cyclodextrin-tethered ruthenium complexes.

Chemistry (Weinheim an der Bergstrasse, Germany) 20100125

Potential of mean force of association of large hydrophobic particles: toward the nanoscale limit.

The journal of physical chemistry. B 20100121

Host-guest directed assembly of gold nanoparticle arrays.

Langmuir : the ACS journal of surfaces and colloids 20100119

Synthesis and anti-viral activity of azolo-adamantanes against influenza A virus.

Bioorganic & medicinal chemistry 20100115

Structure-reactivity relationships: reactions of a 5-substituted aziadamantane in a resorcin[4]arene-based cavitand.

Organic letters 20100115

2-Dialkynyl derivatives of (N)-methanocarba nucleosides: 'Clickable' A(3) adenosine receptor-selective agonists.

Bioorganic & medicinal chemistry 20100115

The influence of a single thiol group on the electronic and optical properties of the smallest diamondoid adamantane.

The Journal of chemical physics 20100114

Effects of vildagliptin twice daily vs. sitagliptin once daily on 24-hour acute glucose fluctuations.

Journal of diabetes and its complications 20100101

Sensorimotor gating in neurotensin-1 receptor null mice.

Neuropharmacology 20100101

Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs.

Bioorganic & medicinal chemistry 20100101

Anticancer therapeutics that target selenoenzymes: synthesis, characterization, in vitro cytotoxicity, and thioredoxin reductase inhibition of a series of gold(I) complexes containing hydrophilic phosphine ligands.

ChemMedChem 20100101

Photochemical formation and chemistry of long-lived adamantylidene-quinone methides and 2-adamantyl cations.

The Journal of organic chemistry 20100101

Reaching HbA1c goals with saxagliptin in combination with other oral antidiabetic drugs.

Postgraduate medicine 20100101

Antiviral prescriptions to U.S. ambulatory care visits with a diagnosis of influenza before and after high level of adamantane resistance 2005-06 season.

PloS one 20100101

Recent advances on platensimycin: a potential antimicrobial agent.

Current medicinal chemistry 20100101

New class of monoclonal antibodies against severe influenza: prophylactic and therapeutic efficacy in ferrets.

PloS one 20100101

Host-guest complexation studied by fluorescence correlation spectroscopy: adamantane-cyclodextrin inclusion.

International journal of molecular sciences 20100101

Self-assembly of diamondoid molecules and derivatives (MD simulations and DFT calculations).

International journal of molecular sciences 20100101

Selection for resistance to oseltamivir in seasonal and pandemic H1N1 influenza and widespread co-circulation of the lineages.

International journal of health geographics 20100101

Designing inhibitors of M2 proton channel against H1N1 swine influenza virus.

PloS one 20100101

[New blood glucose-lowering drugs in type 2 diabetes: a review of the literature].

Nederlands tijdschrift voor geneeskunde 20100101

Covalent anchoring of chloroperoxidase and glucose oxidase on the mesoporous molecular sieve SBA-15.

International journal of molecular sciences 20100101

Prophylactic and therapeutic efficacy of avian antibodies against influenza virus H5N1 and H1N1 in mice.

PloS one 20100101

Current advances in anti-influenza therapy.

Current medicinal chemistry 20100101

[A study of the interaction of boraadamantane with liposomes].

Biofizika 20100101

Guidelines for identifying homologous recombination events in influenza A virus.

PloS one 20100101

Oseltamivir-resistant pandemic (H1N1)2009 in Yemen - case report.

Virology journal 20100101

5'PPP-RNA induced RIG-I activation inhibits drug-resistant avian H5N1 as well as 1918 and 2009 pandemic influenza virus replication.

Virology journal 20100101

Saxagliptin: a new dipeptidyl peptidase-4 inhibitor for type 2 diabetes.

Cardiology in review 20100101

Use of empirical correlations to determine solvent effects in the solvolysis of S-methyl chlorothioformate.

International journal of molecular sciences 20100101

A meta-analysis of placebo-controlled clinical trials assessing the efficacy and safety of incretin-based medications in patients with type 2 diabetes.

Pharmacology 20100101

Adaphostin toxicity in a sensitive non-small cell lung cancer model is mediated through Nrf2 signaling and heme oxygenase 1.

Journal of experimental & clinical cancer research : CR 20100101

A Validated Stability-indicating Reverse Phase HPLC Assay Method for the Determination of Memantine Hydrochloride Drug Substance with UV-Detection Using Precolumn Derivatization Technique.

Analytical chemistry insights 20100101

Analysis of the nucleophilic solvation effects in isopropyl chlorothioformate solvolysis.

International journal of molecular sciences 20100101

Weight neutrality with the DPP-4 inhibitor, vildagliptin: mechanistic basis and clinical experience.

Vascular health and risk management 20100101

A comprehensive surveillance of adamantane resistance among human influenza A virus isolated from mainland China between 1956 and 2009.

Antiviral therapy 20100101

Genetic characterization of 2008 reassortant influenza A virus (H5N1), Thailand.

Virology journal 20100101

In Vitro Susceptibility of Canine Influenza A (H3N8) Virus to Nitazoxanide and Tizoxanide.

Veterinary medicine international 20100101

Use of the adamantane structure in medicinal chemistry.

Current medicinal chemistry 20100101

A randomized, placebo-controlled, double-blind, prospective trial to evaluate the effect of vildagliptin in new-onset diabetes mellitus after kidney transplantation.

Trials 20100101

A role for calcium-permeable AMPA receptors in synaptic plasticity and learning.

PloS one 20100101

Genomic signature-based identification of influenza A viruses using RT-PCR/electro-spray ionization mass spectrometry (ESI-MS) technology.

PloS one 20100101

Calix[4]arene-click-cyclodextrin and supramolecular structures with watersoluble NIPAAM-copolymers bearing adamantyl units: 'Rings on ring on chain'.

Beilstein journal of organic chemistry 20100101

Prevention and treatment of influenza with hyperimmune bovine colostrum antibody.

PloS one 20100101

Influenza virus non-structural protein 1 (NS1) disrupts interferon signaling.

PloS one 20100101

Exploring cell tropism as a possible contributor to influenza infection severity.

PloS one 20100101

Comprehensive assessment of 2009 pandemic influenza A (H1N1) virus drug susceptibility in vitro.

Antiviral therapy 20100101

In vitro susceptibility and virological outcome to darunavir and lopinavir are independent of HIV type-1 subtype in treatment-naive patients.

Antiviral therapy 20100101

Iota-carrageenan is a potent inhibitor of influenza A virus infection.

PloS one 20100101

Glycolipid-Dependent, Protease Sensitive Internalization of Pseudomonas aeruginosa Into Cultured Human Respiratory Epithelial Cells.

The open microbiology journal 20100101

[Treatment of asthenic disorders in patients with psychoautonomic syndrome: results of a multicenter study on efficacy and safety of ladasten].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101

[Prospects for using ladasten preparations in patients with irritable bowel syndrome].

Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20100101

New treatments in the management of type 2 diabetes: a critical appraisal of saxagliptin.

Diabetes, metabolic syndrome and obesity : targets and therapy 20100101

Adamantane resistance in seasonal human influenza A viruses from Calgary, Alberta (January 2007 to August 2008).

The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale 20100101

Development and validation of a headspace gas chromatographic method for the determination of residual solvents in arterolane (RBx11160) maleate bulk drug.

Journal of pharmacy & bioallied sciences 20100101

Excellent correlation between cathepsin B inhibition and cytotoxicity for a series of palladacycles.

Dalton transactions (Cambridge, England : 2003) 20091228

Formation and size tuning of colloidal microcapsules via host-guest molecular recognition at the liquid-liquid interface.

Langmuir : the ACS journal of surfaces and colloids 20091215

Associative network based on cyclodextrin polymer: a model system for drug delivery.

Biomacromolecules 20091214

Ir(III) and Ru(II) complexes containing triazole-pyridine ligands: luminescence enhancement upon substitution with beta-cyclodextrin.

Chemistry (Weinheim an der Bergstrasse, Germany) 20091207

Precision polyethylene: changes in morphology as a function of alkyl branch size.

Journal of the American Chemical Society 20091202

Exploration of endocrine-disrupting chemicals on estrogen receptor alpha by the agonist/antagonist differential-docking screening (AADS) method: 4-(1-adamantyl)phenol as a potent endocrine disruptor candidate.

Toxicology letters 20091201

Efficacy and safety comparison between the DPP-4 inhibitor vildagliptin and the sulfonylurea gliclazide after two years of monotherapy in drug-naïve patients with type 2 diabetes.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20091201

Insulinotropic actions of nateglinide in type 2 diabetic patients and effects on dipeptidyl peptidase-IV activity and glucose-dependent insulinotropic polypeptide degradation.

European journal of endocrinology 20091201

Synthesis and structural characterization of copper(I) complexes bearing N-methyl-1,3,5-triaza-7-phosphaadamantane (mPTA): cytotoxic activity evaluation of a series of water soluble Cu(I) derivatives containing PTA, PTAH and mPTA ligands.

Journal of inorganic biochemistry 20091201

Saxagliptin added to a thiazolidinedione improves glycemic control in patients with type 2 diabetes and inadequate control on thiazolidinedione alone.

The Journal of clinical endocrinology and metabolism 20091201

Mass spectrometry and UV-VIS spectrophotometry of ruthenium(II) [RuClCp(mPTA)2](OSO2CF3)2 complex in solution.

Rapid communications in mass spectrometry : RCM 20091201

Isolation, structure and biological activities of platensimycin B4 from Streptomyces platensis.

The Journal of antibiotics 20091201

Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice.

The Journal of clinical investigation 20091201

Exploration of the DPP-4 inhibitors with a focus on saxagliptin.

Expert opinion on pharmacotherapy 20091201

Role of the incretin pathway in the pathogenesis of type 2 diabetes mellitus.

Cleveland Clinic journal of medicine 20091201

Oseltamivir-resistant influenza A pandemic (H1N1) 2009 virus, Hong Kong, China.

Emerging infectious diseases 20091201

Outbreak of antiviral drug-resistant influenza a in long-term care facility, Illinois, USA, 2008.

Emerging infectious diseases 20091201

A(H5N1) Virus Evolution in South East Asia.

Viruses 20091201

Total synthesis of platensimycin and related natural products.

Journal of the American Chemical Society 20091125

Construction and charge-transfer complexation of adamantane-based macrocycles and a cage with aromatic ring moieties.

The Journal of organic chemistry 20091120

Modulation of arsenic trioxide-induced apoptosis by genistein and functionally related agents in U937 human leukaemia cells. Regulation by ROS and mitogen-activated protein kinases.

Chemico-biological interactions 20091110

Photoinitiated domino reactions: N-(adamantyl)phthalimides and N-(adamantylalkyl)phthalimides.

The Journal of organic chemistry 20091106

Oxidation of cyclohexane by high-valent iron bispidine complexes: tetradentate versus pentadentate ligands.

Inorganic chemistry 20091102

Saxagliptin (Onglyza) for type 2 diabetes.

The Medical letter on drugs and therapeutics 20091102

Cognitive effects of psychotomimetic drugs in rats discriminating number cues.

Psychopharmacology 20091101

Modulation of glycosphingolipid metabolism significantly improves hepatic insulin sensitivity and reverses hepatic steatosis in mice.

Hepatology (Baltimore, Md.) 20091101

Synthesis and biological evaluation of chromium bioorganometallics based on the antibiotic platensimycin lead structure.

ChemMedChem 20091101

Vildagliptin in clinical practice: a review of literature.

Expert opinion on pharmacotherapy 20091101

Genomic events underlying the changes in adamantane resistance among influenza A(H3N2) viruses during 2006-2008.

Influenza and other respiratory viruses 20091101

DPP-4 inhibitors in clinical practice.

Postgraduate medicine 20091101

cis-Bis[(1-adamantylmeth-yl)amine-κN]-dichloridoplatinum(II) N,N-dimethyl-formamide solvate.

Acta crystallographica. Section E, Structure reports online 20091101

Adamantane-1-ammonium benzoate.

Acta crystallographica. Section E, Structure reports online 20091101

2-(Methoxy-meth-yl)adamantan-2-yl 2-methyl-acrylate.

Acta crystallographica. Section E, Structure reports online 20091101

Macromolecular Recognition of Cyclodextrin: Inversion of Selectivity of β-Cyclodextrin toward Adamantyl Groups Induced by Macromolecular Chains.

Macromolecular rapid communications 20091019

Insights from investigating the interactions of adamantane-based drugs with the M2 proton channel from the H1N1 swine virus.

Biochemical and biophysical research communications 20091016

Supramolecular surface modification and solubilization of single-walled carbon nanotubes with cyclodextrin complexation.

Chemistry, an Asian journal 20091005

Comparison of vildagliptin and thiazolidinedione as add-on therapy in patients inadequately controlled with metformin: results of the GALIANT trial--a primary care, type 2 diabetes study.

Diabetes, obesity & metabolism 20091001

Effect of saxagliptin monotherapy in treatment-naïve patients with type 2 diabetes.

Current medical research and opinion 20091001

Vildagliptin therapy and hypoglycaemia in Muslim type 2 diabetes patients during Ramadan.

International journal of clinical practice 20091001

Development and validation of a liquid chromatography-tandem mass spectrometry method for the determination of ST1926, a novel oral antitumor agent, adamantyl retinoid derivative, in plasma of patients in a Phase I study.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091001

New SPE loading material for affinity-based separation of cyclodextrins from drug:CD complexes in order to overcome Beer's law deviations.

Journal of separation science 20091001

Call for comparative effectiveness research: lowering A1c with sitagliptin, saxagliptin, or cinnamon.

Journal of managed care pharmacy : JMCP 20091001

Prolactin-releasing peptide effects in the rat brain are mediated through the Neuropeptide FF receptor.

The European journal of neuroscience 20091001

Guidelines on management of human infection with the novel virus influenza A (H1N1)--a report from the Hospital das Clínicas of the University of São Paulo.

Clinics (Sao Paulo, Brazil) 20091001

Effect of dipeptidyl peptidase-IV (DPP-IV) inhibitor (Vildagliptin) on peripheral nerves in streptozotocin-induced diabetic rats.

Archives of medical research 20091001

N-p-Tolyladamantane-1-carboxamide.

Acta crystallographica. Section E, Structure reports online 20091001

SeqMonitor: influenza analysis pipeline and visualization.

PLoS currents 20090922

A novel class of highly potent multidrug resistance reversal agents: disubstituted adamantyl derivatives.

Bioorganic & medicinal chemistry letters 20090915

Microcalorimetric investigation on the formation of supramolecular nanoassemblies of associative polymers loaded with gadolinium chelate derivatives.

International journal of pharmaceutics 20090911

Kinetic study of neuropeptide Y (NPY) proteolysis in blood and identification of NPY3-35: a new peptide generated by plasma kallikrein.

The Journal of biological chemistry 20090911

Common binding site for externally and internally applied AMPA receptor channel blockers.

Journal of molecular neuroscience : MN 20090901

The efficacy and safety of saxagliptin when added to metformin therapy in patients with inadequately controlled type 2 diabetes with metformin alone.

Diabetes care 20090901

The extracellular calcium-sensing receptor is expressed in the cumulus-oocyte complex in mammals and modulates oocyte meiotic maturation.

Reproduction (Cambridge, England) 20090901

Angiotensin-converting enzyme and dipeptidyl peptidase IV inhibitors: an increased risk of angioedema.

Hypertension (Dallas, Tex. : 1979) 20090901

Dipeptidyl peptidase-IV inhibitor use associated with increased risk of ACE inhibitor-associated angioedema.

Hypertension (Dallas, Tex. : 1979) 20090901

Dynamics of antiviral-resistant influenza viruses in the Netherlands, 2005-2008.

Antiviral research 20090901

Saxagliptin added to a submaximal dose of sulphonylurea improves glycaemic control compared with uptitration of sulphonylurea in patients with type 2 diabetes: a randomised controlled trial.

International journal of clinical practice 20090901

Electron microscopical study to assess the in vitro effects of the synthetic trioxolane OZ78 against the liver fluke, Fasciola hepatica.

Parasitology 20090901

FDA approves saxagliptin for type 2 diabetes.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090901

Defining the importance of daily glycemic control and implications for type 2 diabetes management.

Postgraduate medicine 20090901

Oxyfunctionalization of non-natural targets by dioxiranes. 6. On the selective hydroxylation of cubane.

Organic letters 20090820

Efficient guest inclusion by β-cyclodextrin attached to the ends of DNA oligomers upon hybridization to various DNA conjugates.

Bioconjugate chemistry 20090819

Large footprint pyrene chromophores anchored to planar and colloidal metal oxide thin films.

Langmuir : the ACS journal of surfaces and colloids 20090818

Systematic studies using 2-(1-adamantylethynyl)pyrimidine-5-carbaldehyde as a starting material in Soai's asymmetric autocatalysis.

Chemistry (Weinheim an der Bergstrasse, Germany) 20090817

Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis.

Bioorganic & medicinal chemistry letters 20090815

Isoplatensimycin: Synthesis and biological evaluation.

Bioorganic & medicinal chemistry letters 20090815

Reversible photoisomerization of an azobenzene-functionalized self-assembled monolayer probed by sum-frequency generation vibrational spectroscopy.

Physical chemistry chemical physics : PCCP 20090807

Access to flavones via a microwave-assisted, one-pot Sonogashira-carbonylation-annulation reaction.

Organic letters 20090806

The effect of a full agonist/antagonist of the D1 receptor on locomotor activity, sensorimotor gating and cognitive function in dizocilpine-treated rats.

The international journal of neuropsychopharmacology 20090801

Comparison of vildagliptin and metformin monotherapy in elderly patients with type 2 diabetes: a 24-week, double-blind, randomized trial.

Diabetes, obesity & metabolism 20090801

Unsymmetrical non-adamantyl N,N'-diaryl urea and amide inhibitors of soluble expoxide hydrolase.

Bioorganic & medicinal chemistry letters 20090801

Adaptability and selectivity of human peroxisome proliferator-activated receptor (PPAR) pan agonists revealed from crystal structures.

Acta crystallographica. Section D, Biological crystallography 20090801

Mechanism of action of inhibitors of dipeptidyl-peptidase-4 (DPP-4).

Best practice & research. Clinical endocrinology & metabolism 20090801

Clinical results of treating type 2 diabetic patients with sitagliptin, vildagliptin or saxagliptin--diabetes control and potential adverse events.

Best practice & research. Clinical endocrinology & metabolism 20090801

2,5-Dioxopyrrolidin-1-yl adamantane-1-carboxyl-ate.

Acta crystallographica. Section E, Structure reports online 20090801

3-(1-Adamantylamino)-3-methyl-1-phenyl-quinoline-2,4(1H,3H)-dione.

Acta crystallographica. Section E, Structure reports online 20090801

Adamantane-1-thio-amide.

Acta crystallographica. Section E, Structure reports online 20090801

Susceptibility of antiviral drugs against 2009 influenza A (H1N1) virus.

Biochemical and biophysical research communications 20090731

Unexpected fluorescent behavior of a 4-amino-1,8-naphthalimide derived beta-cyclodextrin: conformation analysis and sensing properties.

Chemical communications (Cambridge, England) 20090721

A novel benzimidazole analogue inhibits the hypoxia-inducible factor (HIF)-1 pathway.

Biochemical and biophysical research communications 20090717

Chemoselective and biomimetic hydroxylation of hydrocarbons by non-heme micro-oxo-bridged diiron(III) catalysts using m-CPBA as oxidant.

Dalton transactions (Cambridge, England : 2003) 20090714

A theoretical examination of known and hypothetical clathrate hydrate materials.

The Journal of chemical physics 20090714

The dynamic side of the Hofmeister effect: a single-molecule nanopore study of specific complex formation.

Chemphyschem : a European journal of chemical physics and physical chemistry 20090713

Anisotropic magnetic behavior of anionic Ce@C82 carbene adducts.

Journal of the American Chemical Society 20090708

Synthesis and reactivity of functionalized binary and ternary thiometallate complexes [(RT)4S6], [(RSn)3S4]2-, [(RT)2(CuPPh3)6S6], and [(RSn)6(OMe)6Cu2S6]4- (R=C2H4COOH, CMe2CH2COMe; T=Ge, Sn).

Chemistry (Weinheim an der Bergstrasse, Germany) 20090706

Preparation, structure, and metallophilic interactions of dinuclear silver(I) and copper(I) complexes of selenium diimides.

Inorganic chemistry 20090706

Clean and direct synthesis of alpha,alpha'-bithiophenes and bipyrroles by metal-free oxidative coupling using recyclable hypervalent iodine(III) reagents.

Chemical & pharmaceutical bulletin 20090701

Influenza genome analysis using pyrosequencing method: current applications for a moving target.

Expert review of molecular diagnostics 20090701

Investigation into adamantane-based M2 inhibitors with FB-QSAR.

Medicinal chemistry (Shariqah (United Arab Emirates)) 20090701

4,8,9,10-Tetra-kis(4-fluoro-phen-yl)-1,3-diaza-tricyclo-[3.3.1.1]decan-6-one.

Acta crystallographica. Section E, Structure reports online 20090701

4-(1-Adamantylmeth-yl)-N-(2-chloro-9-isopropyl-9H-purin-6-yl)aniline.

Acta crystallographica. Section E, Structure reports online 20090701

Stereoelectronic effect for the selectivity in C-H insertion of alkylidene carbenes and its application to the synthesis of platensimycin.

Journal of the American Chemical Society 20090624

Z-selective olefin metathesis processes catalyzed by a molybdenum hexaisopropylterphenoxide monopyrrolide complex.

Journal of the American Chemical Society 20090617

Effect of ligand steric properties and halide identity on the mechanism for oxidative addition of haloarenes to trialkylphosphine Pd(0) complexes.

Journal of the American Chemical Society 20090617

Targeting angiogenesis via a c-Myc/hypoxia-inducible factor-1alpha-dependent pathway in multiple myeloma.

Cancer research 20090615

Bonding or nonbonding? Description or explanation? 'Confinement bonding' of He@adamantane.

Chemistry (Weinheim an der Bergstrasse, Germany) 20090608

The origin and global emergence of adamantane resistant A/H3N2 influenza viruses.

Virology 20090605

Attenuation of cisplatin nephrotoxicity by inhibition of soluble epoxide hydrolase.

Cell biology and toxicology 20090601

Highly twisted adamantyl arotinoids: synthesis, antiproliferative effects and RXR transactivation profiles.

European journal of medicinal chemistry 20090601

Pharmacokinetics of the dipeptidyl peptidase 4 inhibitor saxagliptin in rats, dogs, and monkeys and clinical projections.

Drug metabolism and disposition: the biological fate of chemicals 20090601

Bradykinin inhibits the transient outward K+ current in mouse Schwann cells via the cAMP/PKA pathway.

American journal of physiology. Cell physiology 20090601

Neurotensin inhibition of GABAergic transmission via mGluR-induced endocannabinoid signalling in rat periaqueductal grey.

The Journal of physiology 20090601

Long-term 2-year safety and efficacy of vildagliptin compared with rosiglitazone in drug-naïve patients with type 2 diabetes mellitus.

Diabetes, obesity & metabolism 20090601

Soluble epoxide inhibition is protective against cerebral ischemia via vascular and neural protection.

The American journal of pathology 20090601

SHP and Sin3A expression are essential for adamantyl-substituted retinoid-related molecule-mediated nuclear factor-kappaB activation, c-Fos/c-Jun expression, and cellular apoptosis.

Molecular cancer therapeutics 20090601

Extrapolating from sequence--the 2009 H1N1 'swine' influenza virus.

Nature biotechnology 20090601

Comparison of vildagliptin and pioglitazone in patients with type 2 diabetes inadequately controlled with metformin.

Diabetes, obesity & metabolism 20090601

Saxagliptin given in combination with metformin as initial therapy improves glycaemic control in patients with type 2 diabetes compared with either monotherapy: a randomized controlled trial.

Diabetes, obesity & metabolism 20090601

Oseltamivir- and amantadine-resistant influenza viruses A (H1N1).

Emerging infectious diseases 20090601

What is the optimal therapy for patients with H5N1 influenza?

PLoS medicine 20090601

[Pharmacological sheet. Vildagliptin, oral administration (GALVUS)].

Journal de pharmacie de Belgique 20090601

3-(1-Adamant-yl)-6-methyl-3-(3-methyl-benz-yl)isochroman-1-one.

Acta crystallographica. Section E, Structure reports online 20090601

(1-Adamant-yl){4-[(2-chloro-9-isopropyl-9H-purin-6-yl)aminometh-yl]phen-yl}methanone trichloro-methane solvate.

Acta crystallographica. Section E, Structure reports online 20090601

[1-(1-Adamantylamino)ethyl-idene]oxonium methane-sulfonate.

Acta crystallographica. Section E, Structure reports online 20090601

6-(1-Adamant-yl)-3-(2-fluoro-phen-yl)-1,2,4-triazolo[3,4-b][1,3,4]thia-diazole.

Acta crystallographica. Section E, Structure reports online 20090601

Altering the electronic properties of diamondoids through encapsulating small particles.

Journal of physics. Condensed matter : an Institute of Physics journal 20090527

Highly selective hydroxylation of alkanes catalyzed by (micro-oxo)bis(micro-carboxylato)-bridged diiron(III) complexes: involvement of mononuclear iron(III) species in catalysis.

Dalton transactions (Cambridge, England : 2003) 20090521

Rapid spread of drug-resistant influenza A viruses in the Basque Country, northern Spain, 2000-1 to 2008-9.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20090521

Synaptic scaling requires the GluR2 subunit of the AMPA receptor.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20090520

Reinvestigation of a Ru(2)-incorporated polyoxometalate dioxygenase precatalyst, '[WZnRu(2)(III)(H(2)O)(OH)(ZnW(9)O(34))(2)](11-)': evidence for marginal, <or=0.2 equivalents of Ru incorporation plus faster catalysis by physical mixtures of [Ru(II)(DMSO)(4)Cl(2)] and the parent polyoxometalate [WZn(3)(H(2)O)(2)(ZnW(9)O(34))(2)](12-).

Inorganic chemistry 20090518

Synthesis and evaluation of carbamate prodrugs of SQ109 as antituberculosis agents.

Bioorganic & medicinal chemistry letters 20090515

Discovery and structure-activity relationships of pentanedioic acid diamides as potent inhibitors of 11beta-hydroxysteroid dehydrogenase type I.

Bioorganic & medicinal chemistry letters 20090515

Modeling kinetics of subcellular disposition of chemicals.

Chemical reviews 20090513

Mechanism of drug inhibition and drug resistance of influenza A M2 channel.

Proceedings of the National Academy of Sciences of the United States of America 20090505

Oxidative stress by targeted agents promotes cytotoxicity in hematologic malignancies.

Antioxidants & redox signaling 20090501

Efficacy and tolerability of vildagliptin in patients with type 2 diabetes inadequately controlled with metformin monotherapy.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20090501

An isotropic chemical shift-chemical shift anisotropic correlation experiment using discrete magic angle turning.

Journal of magnetic resonance (San Diego, Calif. : 1997) 20090501

Vildagliptin plus metformin combination therapy provides superior glycaemic control to individual monotherapy in treatment-naive patients with type 2 diabetes mellitus.

Diabetes, obesity & metabolism 20090501

Influenza virus resistance to antiviral agents: a plea for rational use.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090501

Beta-cyclodextrin-modified CdSe/ZnS quantum dots for sensing and chiroselective analysis.

Nano letters 20090501

Study of the pharmacokinetic interaction of vildagliptin and metformin in patients with type 2 diabetes.

Current medical research and opinion 20090501

Islet enhancer vildagliptin: a powerful partner with metformin for the treatment of patients with type 2 diabetes.

Diabetes, obesity & metabolism 20090501

The scientific evidence: vildagliptin and the benefits of islet enhancement.

Diabetes, obesity & metabolism 20090501

Translating science into clinical practice: focus on vildagliptin in combination with metformin.

Diabetes, obesity & metabolism 20090501

[The value of incretin based therapies].

Deutsche medizinische Wochenschrift (1946) 20090501

Hedging against antiviral resistance during the next influenza pandemic using small stockpiles of an alternative chemotherapy.

PLoS medicine 20090501

Saxagliptin: a new dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes.

Advances in therapy 20090501

Changes in CREB (SER133) content and DNA-binding activity of transcriptional factors in rat brain cells against the background of ladasten exposure.

Bulletin of experimental biology and medicine 20090501

(1-Adamant-yl)(4-amino-phen-yl)methanol.

Acta crystallographica. Section E, Structure reports online 20090501

A soluble sulfogalactosyl ceramide mimic promotes Delta F508 CFTR escape from endoplasmic reticulum associated degradation.

Chemistry & biology 20090424

Self-assembled monolayers of 2-Adamantanethiol on Au{111}: control of structure and displacement.

The journal of physical chemistry. A 20090423

Update: influenza activity--United States, September 28, 2008-April 4, 2009, and composition of the 2009-10 influenza vaccine.

MMWR. Morbidity and mortality weekly report 20090417

Highly enantioselective organocatalytic oxidative kinetic resolution of secondary alcohols using chirally modified AZADOs.

Organic letters 20090416

Synthesis and pharmacological evaluation of (2-oxaadamant-1-yl)amines.

Bioorganic & medicinal chemistry 20090415

Exploring a pocket for polycycloaliphatic groups in the CXCR3 receptor with the aid of a modular synthetic strategy.

Bioorganic & medicinal chemistry letters 20090415

Vibrational analysis as a powerful tool in structure elucidation of polyarsenicals: a DFT-based investigation of arsenicin A.

Physical chemistry chemical physics : PCCP 20090414

[Incretin related agents for treatment of diabetes mellitus].

Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20090410

Ionic recognition by 7-nitro-1,3,5-triaza adamantane: first thermodynamic study.

The journal of physical chemistry. B 20090409

Wrenchnolol derivative optimized for gene activation in cells.

Journal of the American Chemical Society 20090408

In situ spectroscopic, electrochemical, and theoretical studies of the photoinduced host-guest electron transfer that precedes unusual host-mediated alkane photooxidation.

Journal of the American Chemical Society 20090408

Characterization of ionotropic glutamate receptors in insect neuro-muscular junction.

Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20090401

Vildagliptin enhances islet responsiveness to both hyper- and hypoglycemia in patients with type 2 diabetes.

The Journal of clinical endocrinology and metabolism 20090401

Evidence for solution-state nonlinearity of sp-carbon chains based on IR and Raman spectroscopy: violation of mutual exclusion.

Journal of the American Chemical Society 20090401

Mechanism of action of species-selective P2X(7) receptor antagonists.

British journal of pharmacology 20090401

Perspectives on influenza virus infection.

Pediatrics and neonatology 20090401

Reversible phase transfer of (CdSe/ZnS) quantum dots between organic and aqueous solutions.

ACS nano 20090324

Synthetic studies on siphonariid polypropionates: synthesis and isomerization of the caloundrin B trioxaadamantane ring system.

Organic letters 20090319

N-H and N=C bond formation via germanium(III) diradicaloid intermediates and C-S bond cleavage in reactions of the digermyne Ar'GeGeAr' (Ar' = C6H3-2,6-(C6H3-2,6-Pr(i)2)2) with azides.

Inorganic chemistry 20090316

Synthesis and biological evaluation of platensimycin analogs.

Bioorganic & medicinal chemistry letters 20090315

Synthesis and reactions of mono- and dinuclear Ni(I) thiolate complexes.

Inorganic chemistry 20090302

Selective P2X(7) receptor antagonists for chronic inflammation and pain.

Purinergic signalling 20090301

Adamantane derivatives of thiazolyl-N-substituted amide, as possible non-steroidal anti-inflammatory agents.

European journal of medicinal chemistry 20090301

Evolution of drug resistance in multiple distinct lineages of H5N1 avian influenza.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20090301

Ethanol withdrawal provokes opening of the mitochondrial membrane permeability transition pore in an estrogen-preventable manner.

The Journal of pharmacology and experimental therapeutics 20090301

Absorption, metabolism, and excretion of [14C]vildagliptin, a novel dipeptidyl peptidase 4 inhibitor, in humans.

Drug metabolism and disposition: the biological fate of chemicals 20090301

Disposition of vildagliptin, a novel dipeptidyl peptidase 4 inhibitor, in rats and dogs.

Drug metabolism and disposition: the biological fate of chemicals 20090301

Dipeptidyl-peptidase-IV inhibition augments postprandial lipid mobilization and oxidation in type 2 diabetic patients.

The Journal of clinical endocrinology and metabolism 20090301

Human influenza A viruses isolated in South America: genetic relations, adamantane resistance and vaccine strain match.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20090301

Studies on depigmenting activities of dihydroxyl benzamide derivatives containing adamantane moiety.

Bioorganic & medicinal chemistry letters 20090301

DPP4 inhibitors: from sitagliptin monotherapy to the new alogliptin-pioglitazone combination therapy.

Advances in therapy 20090301

Saxagliptin: a new DPP-4 inhibitor for the treatment of type 2 diabetes mellitus.

Advances in therapy 20090301

Soluble epoxide hydrolase: a new target for cardioprotection.

Current opinion in investigational drugs (London, England : 2000) 20090301

Grunwald-Winstein analysis: isopropyl chloroformate solvolysis revisited.

International journal of molecular sciences 20090301

Corrrelation of the specific rates of solvolysis of ethyl fluoroformate using the extended Grunwald-Winstein equation.

International journal of molecular sciences 20090301

[Vildagliptin (Galvus) and fixed combination vildagliptine-metformin (Eucreas) in the treatment of type 2 diabetes].

Revue medicale de Liege 20090301

Antiviral resistance in influenza viruses circulating in Central and South America based on the detection of established genetic markers.

Influenza and other respiratory viruses 20090301

Pseudo-capsule assemblies characterized by 19F NMR techniques.

Journal of the American Chemical Society 20090225

Enantioselective reactions of donor/acceptor carbenoids derived from alpha-aryl-alpha-diazoketones.

Organic letters 20090219

Design and synthesis of 1,2-annulated adamantane piperidines with anti-influenza virus activity.

Bioorganic & medicinal chemistry 20090215

Update: influenza activity - United States, September 28, 2008--January 31, 2009.

MMWR. Morbidity and mortality weekly report 20090213

Total synthesis of (-)-platensimycin, a novel antibacterial agent.

The Journal of organic chemistry 20090206

Efficient cross-polarization using a composite 0 degrees pulse for NMR studies on static solids.

Journal of magnetic resonance (San Diego, Calif. : 1997) 20090201

Reduction of glycosphingolipid biosynthesis stimulates biliary lipid secretion in mice.

Hepatology (Baltimore, Md.) 20090201

Vildagliptin dose-dependently improves glycemic control in Japanese patients with type 2 diabetes mellitus.

Diabetes research and clinical practice 20090201

Fifty-two-week efficacy and safety of vildagliptin vs. glimepiride in patients with type 2 diabetes mellitus inadequately controlled on metformin monotherapy.

Diabetes, obesity & metabolism 20090201

Improving the stability and sensing of electrochemical biosensors by employing trithiol-anchoring groups in a six-carbon self-assembled monolayer.

Analytical chemistry 20090201

Drug evaluation: vildagliptin-metformin single-tablet combination.

Advances in therapy 20090201

2-(1-Adamant-yl)-1-{4-[(2-chloro-9-isopropyl-9H-purin-6-yl)amino-meth-yl]phen-yl}ethanone.

Acta crystallographica. Section E, Structure reports online 20090201

Multivalent scaffolds for affinity maturation of small molecule cell surface binders and their application to prostate tumor targeting.

Journal of medicinal chemistry 20090122

In vivo profiling of DPP4 inhibitors reveals alterations in collagen metabolism and accumulation of an amyloid peptide in rat plasma.

Biochemical pharmacology 20090115

Quasiequilibrium states in thermotropic liquid crystals studied by multiple-quantum NMR.

The Journal of chemical physics 20090114

Synthesis and anti-HIV studies of 2- and 3-adamantyl-substituted thiazolidin-4-ones.

European journal of medicinal chemistry 20090101

Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto-Kakizaki rats.

Clinical science (London, England : 1979) 20090101

Adamantane/beta-cyclodextrin affinity biosensors based on single-walled carbon nanotubes.

Biosensors & bioelectronics 20090101

Pharmacokinetics and pharmacodynamics of vildagliptin in healthy Chinese volunteers.

Journal of clinical pharmacology 20090101

Inhibition of dipeptidyl peptidase-4 by vildagliptin during glucagon-like Peptide 1 infusion increases liver glucose uptake in the conscious dog.

Diabetes 20090101

Dipeptidyl peptidase-4 inhibition by vildagliptin and the effect on insulin secretion and action in response to meal ingestion in type 2 diabetes.

Diabetes care 20090101

Treatment with the dipeptidyl peptidase-4 inhibitor vildagliptin improves fasting islet-cell function in subjects with type 2 diabetes.

The Journal of clinical endocrinology and metabolism 20090101

Polycyclic compounds: ideal drug scaffolds for the design of multiple mechanism drugs?

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20090101

Organic ligand binding by a hydrophobic cavity in a designed tetrameric coiled-coil protein.

Chemistry (Weinheim an der Bergstrasse, Germany) 20090101

Emerging drug candidates of dipeptidyl peptidase IV (DPP IV) inhibitor class for the treatment of Type 2 Diabetes.

Current drug targets 20090101

Incretin mimetics and DPP-4 inhibitors: new approach to treatment of type 2 diabetes mellitus.

Mymensingh medical journal : MMJ 20090101

Ca(2+) permeable AMPA receptor induced long-term potentiation requires PI3/MAP kinases but not Ca/CaM-dependent kinase II.

PloS one 20090101

Efforts towards the identification of simpler platensimycin analogues--the total synthesis of oxazinidinyl platensimycin.

Chemistry (Weinheim an der Bergstrasse, Germany) 20090101

Molecular characterization of highly pathogenic H5N1 avian influenza A viruses isolated from raccoon dogs in China.

PloS one 20090101

Highly pathogenic avian influenza virus subtype H5N1 in Africa: a comprehensive phylogenetic analysis and molecular characterization of isolates.

PloS one 20090101

A dimeric magnesium(I) compound as a facile two-center/two-electron reductant.

Angewandte Chemie (International ed. in English) 20090101

Reducing glycosphingolipid content in adipose tissue of obese mice restores insulin sensitivity, adipogenesis and reduces inflammation.

PloS one 20090101

[Effects of antiparkinsonian drug hemantane on the level and metabolism of biogenic monoamines in brain structures of C57BL/6 mice].

Eksperimental'naia i klinicheskaia farmakologiia 20090101

Mimicking natural globular structures with rigid scaffolds based on adamantane.

Advances in experimental medicine and biology 20090101

A supramolecular approach for preparation of size-controlled nanoparticles.

Angewandte Chemie (International ed. in English) 20090101

[Effects of novel antiviral agents on HIV-1 replication].

Voprosy virusologii 20090101

Evolution of the M gene of the influenza A virus in different host species: large-scale sequence analysis.

Virology journal 20090101

[Ladasten, the new drug with psychostimulant and anxiolytic actions in treatment of neurasthenia (results of the comparative clinical study with placebo)].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101

Identification and characterisation of a novel anti-viral peptide against avian influenza virus H9N2.

Virology journal 20090101

Influence of conjugated linoleic acid on the porcine immune response and morbidity: a randomized controlled trial.

Lipids in health and disease 20090101

Pandemic influenza: implications for occupational medicine.

Journal of occupational medicine and toxicology (London, England) 20090101

Update on the use of memantine in Alzheimer's disease.

Neuropsychiatric disease and treatment 20090101

Rhodium-catalyzed asymmetric enyne cycloisomerization of terminal alkynes and formal total synthesis of (-)-platensimycin.

Angewandte Chemie (International ed. in English) 20090101

Platensimycin activity against mycobacterial beta-ketoacyl-ACP synthases.

PloS one 20090101

[Effect of ladasten on the psychophysiological parameters of healthy volunteers].

Eksperimental'naia i klinicheskaia farmakologiia 20090101

A novel peptide inhibits the influenza virus replication by preventing the viral attachment to the host cells.

International journal of biological sciences 20090101

Quantum mechanical calculation of aqueuous uranium complexes: carbonate, phosphate, organic and biomolecular species.

Chemistry Central journal 20090101

Enhancement of tumour-specific immune responses in vivo by 'MHC loading-enhancer' (MLE).

PloS one 20090101

The feasibility of using high resolution genome sequencing of influenza A viruses to detect mixed infections and quasispecies.

PloS one 20090101

New therapeutic horizons: mapping the future of glycemic control with incretin-based therapy.

The Diabetes educator 20090101

A concise ring-expansion route to the compact core of platensimycin.

Angewandte Chemie (International ed. in English) 20090101

Selection of inhibitor-resistant viral potassium channels identifies a selectivity filter site that affects barium and amantadine block.

PloS one 20090101

Novel pandemic influenza A(H1N1) viruses are potently inhibited by DAS181, a sialidase fusion protein.

PloS one 20090101

Anti-viral properties and mode of action of standardized Echinacea purpurea extract against highly pathogenic avian influenza virus (H5N1, H7N7) and swine-origin H1N1 (S-OIV).

Virology journal 20090101

Prasugrel hydrochloride, dronedarone, and saxagliptin hydrochloride.

Journal of the American Pharmacists Association : JAPhA 20090101

Post-exposure prophylaxis during pandemic outbreaks.

BMC medicine 20090101

P2X(7) Receptors in Neurological and Cardiovascular Disorders.

Cardiovascular psychiatry and neurology 20090101

Influenza in outpatient ILI case-patients in national hospital-based surveillance, Bangladesh, 2007-2008.

PloS one 20090101

Selective Spectrophotometric and Spectrofluorometric Methods for the Determination of Amantadine Hydrochloride in Capsules and Plasma via Derivatization with 1,2-Naphthoquinone-4-sulphonate.

International journal of analytical chemistry 20090101

Free-standing porous supramolecular assemblies of nanoparticles made using a double-templating strategy.

Faraday discussions 20090101

1,3-Di-1-adamantylimidazolium (phthalocyaninato)lithium(I) acetone hemisolvate monohydrate.

Acta crystallographica. Section E, Structure reports online 20090101

1-Bromo-adamantane.

Acta crystallographica. Section E, Structure reports online 20090101

K ATP channels in pig and human intracranial arteries.

European journal of pharmacology 20081228

Molecular puzzle ring: pseudo[1]rotaxane from a flexible cyclodextrin derivative.

Journal of the American Chemical Society 20081217

DPP4 inhibitors for diabetes--what next?

Biochemical pharmacology 20081215

Distribution and dynamics of adamantanes in a lipid bilayer.

Biophysical journal 20081215

Straightforward route to the adamantane clusters [Sn4Q10]4- (Q = S, Se, Te) and use in the assembly of open-framework chalcogenides (Me4N)2M[Sn4Se10] (M = Mn(II), Fe(II), Co(II), Zn(II)) including the first telluride member (Me4N)2Mn[Ge4Te10].

Inorganic chemistry 20081215

Incretin-based therapies in type 2 diabetes: a review of clinical results.

Diabetes research and clinical practice 20081215

New water-soluble azido- and derived tetrazolato-platinum(II) complexes with PTA. Easy metal-mediated synthesis and isolation of 5-substituted tetrazoles.

Dalton transactions (Cambridge, England : 2003) 20081214

Reaction of a sterically encumbered iron(I) aryl/arene with organoazides: formation of an iron(V) bis(imide).

Chemical communications (Cambridge, England) 20081207

Thiamacrocyclic lactones: new Ag(I)-ionophores.

The Journal of organic chemistry 20081205

Construction of the adamantane core of plukenetione-type polycyclic polyprenylated acylphloroglucinols.

The Journal of organic chemistry 20081205

Electronic and steric effects in binding of deep cavitands.

Organic letters 20081204

Efficacy and safety of vildagliptin monotherapy during 2-year treatment of drug-naïve patients with type 2 diabetes: comparison with metformin.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20081201

Characterization of N-(adamantan-1-ylmethyl)-5-[(3R-amino-pyrrolidin-1-yl)methyl]-2-chloro-benzamide, a P2X7 antagonist in animal models of pain and inflammation.

The Journal of pharmacology and experimental therapeutics 20081201

Combination of the dipeptidyl peptidase IV inhibitor LAF237 [(S)-1-[(3-hydroxy-1-adamantyl)ammo]acetyl-2-cyanopyrrolidine] with the angiotensin II type 1 receptor antagonist valsartan [N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl]-L-valine] enhances pancreatic islet morphology and function in a mouse model of type 2 diabetes.

The Journal of pharmacology and experimental therapeutics 20081201

Inhibition of soluble epoxide hydrolase does not protect against endotoxin-mediated hepatic inflammation.

The Journal of pharmacology and experimental therapeutics 20081201

Comparisons of the influenza virus A M2 channel binding affinities, anti-influenza virus potencies and NMDA antagonistic activities of 2-alkyl-2-aminoadamantanes and analogues.

Bioorganic & medicinal chemistry letters 20081201

Saxagliptin, a dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.

IDrugs : the investigational drugs journal 20081201

Development and characterization of new cyclodextrin polymer-based DNA delivery systems.

Bioconjugate chemistry 20081201

Incretin-based therapies: a new potential treatment approach to overcome clinical inertia in type 2 diabetes.

Acta bio-medica : Atenei Parmensis 20081201

Correlation of the rates of solvolysis of two arenesulfonyl chlorides and of trans-beta-styrenesulfonyl chloride - precursors in the development of new pharmaceuticals.

International journal of molecular sciences 20081201

Combination therapy with DPP-4 inhibitors and pioglitazone in type 2 diabetes: theoretical consideration and therapeutic potential.

Vascular health and risk management 20081201

Vildagliptin: a new oral treatment for type 2 diabetes mellitus.

Vascular health and risk management 20081201

Pharmacology and therapeutic potential of sigma(1) receptor ligands.

Current neuropharmacology 20081201

Cu(I) complexes bearing the new sterically demanding and coordination flexible tris(3-phenyl-1-pyrazolyl)methanesulfonate ligand and the water-soluble phosphine 1,3,5-triaza-7-phosphaadamantane or related ligands.

Inorganic chemistry 20081103

Effects of vildagliptin on glucose control in patients with type 2 diabetes inadequately controlled with a sulphonylurea.

Diabetes, obesity & metabolism 20081101

The effect of dipeptidyl peptidase-4 inhibition on gastric volume, satiation and enteroendocrine secretion in type 2 diabetes: a double-blind, placebo-controlled crossover study.

Clinical endocrinology 20081101

Evidence that vildagliptin attenuates deterioration of glycaemic control during 2-year treatment of patients with type 2 diabetes and mild hyperglycaemia.

Diabetes, obesity & metabolism 20081101

Adverse effects of dipeptidyl peptidases 8 and 9 inhibition in rodents revisited.

Diabetes, obesity & metabolism 20081101

Adamantane resistance in influenza A(H1) viruses increased in 2007 in South East Asia but decreased in Australia and some other countries.

Antiviral research 20081101

Soluble epoxide hydrolase inhibition and gene deletion are protective against myocardial ischemia-reperfusion injury in vivo.

American journal of physiology. Heart and circulatory physiology 20081101

Dipeptidyl peptidase-4 as a new target of action for type 2 diabetes mellitus: a systematic review.

Cardiology clinics 20081101

Replacement of sublineages of avian influenza (H5N1) by reassortments, sub-Saharan Africa.

Emerging infectious diseases 20081101

Extended Grunwald-Winstein analysis - LFER used to gauge solvent effects in p-nitrophenyl chloroformate solvolysis.

International journal of molecular sciences 20081101

[Future therapeutic options and their indications: transplantation and the possibilities of regenerative therapy for diabetes type 1].

MMW Fortschritte der Medizin 20081030

Isolation, structure and fatty acid synthesis inhibitory activities of platensimycin B1-B3 from Streptomyces platensis.

Chemical communications (Cambridge, England) 20081028

Phosphaalkenes as long-lived phosphorus cluster surface functional groups: intramolecular P=C addition to a niobium-supported P7 cage.

Inorganic chemistry 20081020

Tetradehydroadamantane-1,3,5,7-di- and tetracations and their helium and hydride inclusion complexes: spherical aromaticity and evidence for a bonding interaction between carbon and helium.

The journal of physical chemistry. A 20081009

X-ray crystal structure of human heme oxygenase-1 in complex with 1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone: a common binding mode for imidazole-based heme oxygenase-1 inhibitors.

Journal of medicinal chemistry 20081009

From stochastic pulse optimization to a stereoselective laser pulse sequence: simulation of a chiroptical molecular switch mounted on adamantane.

The journal of physical chemistry. A 20081009

Effect of vildagliptin on glucagon concentration during meals in patients with type 1 diabetes.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20081001

Practical aspects of Lee-Goldburg based CRAMPS techniques for high-resolution 1H NMR spectroscopy in solids: implementation and applications.

Journal of magnetic resonance (San Diego, Calif. : 1997) 20081001

Design, synthesis, and biological evaluation of platensimycin analogues with varying degrees of molecular complexity.

Journal of the American Chemical Society 20081001

Does Gd@C82 have an anomalous endohedral structure? Synthesis and single crystal X-ray structure of the carbene adduct.

Journal of the American Chemical Society 20081001

Control of an outbreak due to an adamantane-resistant strain of influenza A (H3N2) in a chronic care facility.

Infection 20081001

Antivirals and influenza: frequency of resistance.

The Pediatric infectious disease journal 20081001

[Sitagliptin. DPP-4 inhibitors as a useful extension of oral diabetes therapy?].

Deutsche medizinische Wochenschrift (1946) 20081001

Structural analysis of binding of a diamantoid substrate to cytochrome P450 2B4: possible role of Arg 133 in modulation of function and activity of this enzyme.

Neuro endocrinology letters 20081001

Vildagliptin and vildagliptin/metformin: new drug. Same limited efficacy as sitagliptin in type 2 diabetes.

Prescrire international 20081001

Bis[1-(1-adamantyliminomethyl)-2-naphtholato-κN,O]cobalt(II).

Acta crystallographica. Section E, Structure reports online 20081001

Hydrous zinc halide-catalyzed aminosulfonation of hydrocarbons.

Chemical communications (Cambridge, England) 20080928

Adamantyl-substituted retinoid-derived molecules that interact with the orphan nuclear receptor small heterodimer partner: effects of replacing the 1-adamantyl or hydroxyl group on inhibition of cancer cell growth, induction of cancer cell apoptosis, and inhibition of SRC homology 2 domain-containing protein tyrosine phosphatase-2 activity.

Journal of medicinal chemistry 20080925

Stereocontrolled formal synthesis of (+/-)-platensimycin.

Organic letters 20080918

Novel 2,4-methanoadamantane-benzazepine by domino photochemistry of N-(1-adamantyl)phthalimide.

Organic letters 20080918

Design, synthesis, and bioactivity of putative tubulin ligands with adamantane core.

Bioorganic & medicinal chemistry letters 20080915

Inhibition of IkappaB kinase-beta and anticancer activities of novel chalcone adamantyl arotinoids.

Journal of medicinal chemistry 20080911

Crystal structures of rat vitamin D receptor bound to adamantyl vitamin D analogs: structural basis for vitamin D receptor antagonism and partial agonism.

Journal of medicinal chemistry 20080911

Selective methylative homologation: an alternate route to alkane upgrading.

Journal of the American Chemical Society 20080910

Study of secondary relaxation in disordered plastic crystals of isocyanocyclohexane, cyanocyclohexane, and 1-cyanoadamantane.

The Journal of chemical physics 20080907

Recognition of guests by water-stabilized cavitand hosts.

Organic letters 20080904

A simple, efficient, and enantiocontrolled synthesis of a near-structural mimic of platensimycin.

Organic letters 20080904

Robust improvements in fasting and prandial measures of beta-cell function with vildagliptin in drug-naïve patients: analysis of pooled vildagliptin monotherapy database.

Diabetes, obesity & metabolism 20080901

The glucosylceramide synthase inhibitor N-(5-adamantane-1-yl-methoxy-pentyl)-deoxynojirimycin induces sterol regulatory element-binding protein-regulated gene expression and cholesterol synthesis in HepG2 cells.

The Journal of pharmacology and experimental therapeutics 20080901

Cloning and expression of the L-1-amino-2-propanol dehydrogenase gene from Rhodococcus erythropolis, and its application to double chiral compound production.

Applied microbiology and biotechnology 20080901

Highly pathogenic avian influenza virus (H5N1) isolated from whooper swans, Japan.

Emerging infectious diseases 20080901

Atypical retinoids ST1926 and CD437 are S-phase-specific agents causing DNA double-strand breaks: significance for the cytotoxic and antiproliferative activity.

Molecular cancer therapeutics 20080901

Broad-spectrum drugs against viral agents.

International journal of molecular sciences 20080901

The influence of carbon-carbon multiple bonds on the solvolyses of tertiary alkyl halides: A Grunwald-Winstein analysis.

International journal of molecular sciences 20080901

3-Hydroxy-adamantane-1-acetic acid.

Acta crystallographica. Section E, Structure reports online 20080901

Investigations on the 4-quinolone-3-carboxylic acid motif. 2. Synthesis and structure-activity relationship of potent and selective cannabinoid-2 receptor agonists endowed with analgesic activity in vivo.

Journal of medicinal chemistry 20080828

Synthesis of somatostatin analogues containing C-terminal adamantane and their antiproliferative properties.

Journal of medicinal chemistry 20080828

Construction and micellization of a noncovalent double hydrophilic block copolymer.

Chemical communications (Cambridge, England) 20080828

DNA structural distortions induced by ruthenium-arene anticancer compounds.

Journal of the American Chemical Society 20080820

Novel 4-aminoquinolines active against chloroquine-resistant and sensitive P. falciparum strains that also inhibit botulinum serotype A.

Journal of medicinal chemistry 20080814

Synthesis of Al complexes containing phenoxy-imine ligands and their use as the catalyst precursors for efficient living ring-opening polymerisation of epsilon-caprolactone.

Dalton transactions (Cambridge, England : 2003) 20080814

Toward the discovery of potent inhibitors of botulinum neurotoxin A: development of a robust LC MS based assay operational from low to subnanomolar enzyme concentrations.

Chemical communications (Cambridge, England) 20080814

Near-edge X-ray absorption fine structure spectroscopy of diamondoid thiol monolayers on gold.

Journal of the American Chemical Society 20080813

Gamma-cyclodextrin forms a highly compressible complex with 1-adamantanecarboxylic acid.

The journal of physical chemistry. B 20080807

Efficacy and tolerability of vildagliptin in drug-naïve patients with type 2 diabetes and mild hyperglycaemia*.

Diabetes, obesity & metabolism 20080801

Adamantane resistance in circulating human influenza A viruses from Alberta, Canada (1970-2007).

Antiviral research 20080801

Modifying clinical practices to manage influenza in children effectively.

The Pediatric infectious disease journal 20080801

Oseltamivir prescribing in pharmacy-benefits database, United States, 2004-2005.

Emerging infectious diseases 20080801

Molecular epidemiology of A/H3N2 and A/H1N1 influenza virus during a single epidemic season in the United States.

PLoS pathogens 20080801

Incretin mimetics and dipeptidyl peptidase-4 inhibitors: innovative treatment therapies for type 2 diabetes.

Arquivos brasileiros de endocrinologia e metabologia 20080801

Emerging role of dipeptidyl peptidase-4 inhibitors in the management of type 2 diabetes.

Vascular health and risk management 20080801

N-Phenyl-adamantane-1-sulfinamide.

Acta crystallographica. Section E, Structure reports online 20080801

A new polymorph of N-(prop-2-yn-yl)tricyclo-[3.3.1.1]decane-1-carbox-amide.

Acta crystallographica. Section E, Structure reports online 20080801

Mercury-platinum tunneling junctions incorporating supramolecular host-guest assemblies.

Journal of the American Chemical Society 20080730

Early stages of formation of branched host-guest supramolecular polymers.

The journal of physical chemistry. B 20080724

P2 addition to terminal phosphide M[triple bond]P triple bonds: a rational synthesis of cyclo-P3 complexes.

Journal of the American Chemical Society 20080723

Synthesis of (1-adamantylimido)vanadium(V) complexes containing aryloxo, ketimide ligands: effect of ligand substituents in olefin insertion/metathesis polymerization.

Inorganic chemistry 20080721

Chemical understanding of a non-IPR metallofullerene: stabilization of encaged metals on fused-pentagon bonds in La2@C72.

Journal of the American Chemical Society 20080716

Synthesis and structures of crystalline Li, Al and Sn(II) 1-azaallyls and beta-diketiminates derived from [Li{mu,eta3-N(SiMe3)C(Ad)C(H)SiMe3}]2 (Ad = 1-adamantyl).

Dalton transactions (Cambridge, England : 2003) 20080714

Theoretical studies on the structure and symmetry of the transmembrane region of glutamatergic GluR5 receptor.

Journal of medicinal chemistry 20080710

Synthesis, characterization, and in vitro cytotoxicity of some gold(I) and trans platinum(II) thionate complexes containing water-soluble PTA and DAPTA ligands. X-ray crystal structures of [Au(SC4H3N2)(PTA)], trans-[Pt(SC4H3N2)2(PTA)2], trans-[Pt(SC5H4N)2(PTA)2], and trans-[Pt(SC5H4N)2(DAPTA)2].

Inorganic chemistry 20080707

Solid-state molecular rotators of anilinium and adamantylammonium in [Ni(dmit)2](-) salts with diverse magnetic properties.

Inorganic chemistry 20080707

Cucurbit[n]uril formation proceeds by step-growth cyclo-oligomerization.

Journal of the American Chemical Society 20080702

Neuropeptide FF receptors antagonist, RF9, attenuates opioid-evoked hypothermia in mice.

Peptides 20080701

Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials.

Current opinion in clinical nutrition and metabolic care 20080701

From the bench to the bedside: dipeptidyl peptidase IV inhibitors, a new class of oral antihyperglycemic agents.

Current opinion in drug discovery & development 20080701

Three new drugs for type 2 diabetes.

Drug and therapeutics bulletin 20080701

DPP4 inhibitors: a new approach in diabetes treatment.

Advances in therapy 20080701

Enzymatic properties of the neuraminidase of seasonal H1N1 influenza viruses provide insights for the emergence of natural resistance to oseltamivir.

PLoS pathogens 20080701

Evaluation of pharmacokinetic and pharmacodynamic interaction between the dipeptidyl peptidase IV inhibitor vildagliptin, glyburide and pioglitazone in patients with Type 2 diabetes.

International journal of clinical pharmacology and therapeutics 20080701

Peripheral and central routes of administration of quaternary ammonium compound IEM-1460 are equally potent in reducing the severity of nicotine-induced seizures in mice.

Bulletin of experimental biology and medicine 20080701

2-(1-Adamant-yl)-4-bromo-anisole at 123 K.

Acta crystallographica. Section E, Structure reports online 20080701

2-(Tricyclo[3.3.1.1]dec-2-ylamino)ethanol hemihydrate.

Acta crystallographica. Section E, Structure reports online 20080701

Local correlation domains for coupled cluster theory: optical rotation and magnetic-field perturbations.

Physical chemistry chemical physics : PCCP 20080621

Bioconjugation of alkaline phosphatase to mechanically processed, aqueous suspendible electrospun polymer nanofibers for use in chemiluminescent detection assays.

Macromolecular bioscience 20080611

Selective fluorination of adamantanes by an electrochemical method.

The Journal of organic chemistry 20080606

Detection of adamantane-resistant influenza on a microarray.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20080601

Insights into homonuclear decoupling from efficient numerical simulation: techniques and examples.

Journal of magnetic resonance (San Diego, Calif. : 1997) 20080601

Sustained efficacy and reduced hypoglycemia during one year of treatment with vildagliptin added to insulin in patients with type 2 diabetes mellitus.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20080601

Effects of the selective neurotensin antagonist SR 142948A on 3,4-methylenedioxymethamphetamine-induced behaviours in mice.

Neuropharmacology 20080601

Effects of the selective EET antagonist, 14,15-EEZE, on cardioprotection produced by exogenous or endogenous EETs in the canine heart.

American journal of physiology. Heart and circulatory physiology 20080601

Synthesis of platensimycin analogues and their antibiotic potency.

Archiv der Pharmazie 20080601

Effect of food on the pharmacokinetics of a vildagliptin/metformin (50/1000 mg) fixed-dose combination tablet in healthy volunteers.

Current medical research and opinion 20080601

Incretin mimetics and dipeptidyl peptidase 4 inhibitors in clinical trials for the treatment of type 2 diabetes.

Expert opinion on investigational drugs 20080601

Combination treatment in the management of type 2 diabetes: focus on vildagliptin and metformin as a single tablet.

Vascular health and risk management 20080601

N-(2-Hydroxy-ethyl)-N-(tricyclo-[3.3.1.1]dec-2-yl)benzamide.

Acta crystallographica. Section E, Structure reports online 20080601

2-amino-1,3-thiazol-4(5H)-ones as potent and selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: enzyme-ligand co-crystal structure and demonstration of pharmacodynamic effects in C57Bl/6 mice.

Journal of medicinal chemistry 20080522

A bridging hexazene (RNNNNNNR) ligand from reductive coupling of azides.

Journal of the American Chemical Society 20080514

Control over binding stoichiometry and specificity in the supramolecular immobilization of cytochrome c on a molecular printboard.

Organic & biomolecular chemistry 20080507

A simple method for preparation of molecularly imprinted nanofiber materials with signal transduction ability.

Chemical communications (Cambridge, England) 20080507

Design, synthesis, conformational and membrane ion transport studies of proline-adamantane hybrid cyclic depsipeptides.

Biopolymers 20080501

Neonatal tactile stimulation enhances spatial working memory, prefrontal long-term potentiation, and D1 receptor activation in adult rats.

Neurobiology of learning and memory 20080501

Fasciola hepatica: Surface tegumental responses to in vitro and in vivo treatment with the experimental fasciolicide OZ78.

Experimental parasitology 20080501

Selectively increased trace conditioning under the neurotensin agonist PD 149163 in an aversive procedure in which SR 142948A was without intrinsic effect.

Journal of psychopharmacology (Oxford, England) 20080501

K(ATP) channel expression and pharmacological in vivo and in vitro studies of the K(ATP) channel blocker PNU-37883A in rat middle meningeal arteries.

British journal of pharmacology 20080501

Glucose-lowering activity of the dipeptidyl peptidase-4 inhibitor saxagliptin in drug-naive patients with type 2 diabetes.

Diabetes, obesity & metabolism 20080501

Emergence of adamantane-resistant influenza A(H3N2) viruses in Hong Kong between 1997 and 2006.

Journal of medical virology 20080501

Chemical synthesis of 2beta-amino-5alpha-androstane-3alpha,17beta-diol N-derivatives and their antiproliferative effect on HL-60 human leukemia cells.

Bioorganic & medicinal chemistry 20080501

Structure and semisynthesis of platensimide A, produced by Streptomyces platensis.

Organic letters 20080501

Involvement of ionotropic glutamate receptors in the appearance of arecoline tremor in mice.

Neuroscience and behavioral physiology 20080501

Soluble epoxide hydrolase inhibitor, AUDA, prevents early salt-sensitive hypertension.

Frontiers in bioscience : a journal and virtual library 20080501

Dipeptidyl peptidase IV (DPP IV) and related molecules in type 2 diabetes.

Frontiers in bioscience : a journal and virtual library 20080501

Bioequivalence of vildagliptin/metformin fixed-dose combination tablets and a free combination of vildagliptin and metformin in healthy subjects.

International journal of clinical pharmacology and therapeutics 20080501

3,5,7-Tripropyl-1-aza-adamantane-4,6,10-triol.

Acta crystallographica. Section E, Structure reports online 20080501

In vivo neurochemical effects of the NR2B selective NMDA receptor antagonist CR 3394 in 6-hydroxydopamine lesioned rats.

European journal of pharmacology 20080428

Synthesis, structure, and inclusion capabilities of trehalose-based cyclodextrin analogues (cyclotrehalans).

The Journal of organic chemistry 20080418

para-Bridged symmetrical pillar[5]arenes: their Lewis acid catalyzed synthesis and host-guest property.

Journal of the American Chemical Society 20080416

Dipeptidyl peptidase-4 (DPP-4) inhibitors for type 2 diabetes mellitus.

The Cochrane database of systematic reviews 20080416

Inhibition of neuropeptide FF (NPFF)-induced hypothermia and anti-morphine analgesia by RF9, a new selective NPFF receptors antagonist.

Regulatory peptides 20080410

Spectroscopic and electronic structure studies of symmetrized models for reduced members of the dimethylsulfoxide reductase enzyme family.

Journal of the American Chemical Society 20080409

Comparison of vildagliptin and acarbose monotherapy in patients with Type 2 diabetes: a 24-week, double-blind, randomized trial.

Diabetic medicine : a journal of the British Diabetic Association 20080401

Development of a magic-angle spinning nuclear magnetic resonance probe with a cryogenic detection system for sensitivity enhancement.

The Review of scientific instruments 20080401

Novel combination treatment of type 2 diabetes DPP-4 inhibition + metformin.

Vascular health and risk management 20080401

Supramolecular layer-by-layer assembly of 3D multicomponent nanostructures via multivalent molecular recognition.

International journal of molecular sciences 20080401

Design, synthesis, and trypanocidal activity of new aminoadamantane derivatives.

Journal of medicinal chemistry 20080313

Charge-separation in uranium diazomethane complexes leading to C-H activation and chemical transformation.

Journal of the American Chemical Society 20080305

The novel cannabinoid CB1 receptor neutral antagonist AM4113 suppresses food intake and food-reinforced behavior but does not induce signs of nausea in rats.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080301

The effect of age, gender, and body mass index on the pharmacokinetics and pharmacodynamics of vildagliptin in healthy volunteers.

British journal of clinical pharmacology 20080301

Organic blockers escape from trapping in the AMPA receptor channels by leaking into the cytoplasm.

Neuropharmacology 20080301

Characterization of the two major CYP450 metabolites of ozonide (1,2,4-trioxolane) OZ277.

Bioorganic & medicinal chemistry letters 20080301

Islet cell function is as interesting as insulin resistance for T2DM treatment options.

International journal of clinical practice. Supplement 20080301

The islet enhancer vildagliptin: mechanisms of improved glucose metabolism.

International journal of clinical practice. Supplement 20080301

Vildagliptin: clinical trials programme in monotherapy and combination therapy for type 2 diabetes.

International journal of clinical practice. Supplement 20080301

SQ109.

Tuberculosis (Edinburgh, Scotland) 20080301

Effect of antiparkinsonian drug himantane on the content of dopamine transporter DAT protein in rat striatum and cultured pheochromocytoma PC-12 cells.

Bulletin of experimental biology and medicine 20080301

Inhibition of multidrug resistance by adamantylgb3, a globotriaosylceramide analog.

The Journal of biological chemistry 20080222

P-Amino-cyclopentadienylidene-phosphoranes versus P-cyclopentadienyl-iminophosphoranes--tautomeric protic forms of a new bidentate CpPN ligand system.

Dalton transactions (Cambridge, England : 2003) 20080221

Orally active esters of dihydroartemisinin: Synthesis and antimalarial activity against multidrug-resistant Plasmodium yoelii in mice.

Bioorganic & medicinal chemistry letters 20080215

The discovery of adamantyl-derived, inhaled, long acting beta(2)-adrenoreceptor agonists.

Bioorganic & medicinal chemistry letters 20080215

Isolation and characterization of carbene derivatives of La@C82(Cs).

The journal of physical chemistry. A 20080214

Two-photon Lee-Goldburg nuclear magnetic resonance: Simultaneous homonuclear decoupling and signal acquisition.

The Journal of chemical physics 20080207

Measurements of islet function and glucose metabolism with the dipeptidyl peptidase 4 inhibitor vildagliptin in patients with type 2 diabetes.

The Journal of clinical endocrinology and metabolism 20080201

Synthesis, in vitro and in vivo characterization of (64)Cu(I) complexes derived from hydrophilic tris(hydroxymethyl)phosphane and 1,3,5-triaza-7-phosphaadamantane ligands.

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20080201

SAR-oriented discovery of peroxisome proliferator-activated receptor pan agonist with a 4-adamantylphenyl group as a hydrophobic tail.

Bioorganic & medicinal chemistry letters 20080201

Rigid multivalent scaffolds based on adamantane.

The Journal of organic chemistry 20080201

Involvement of DPP-IV catalytic residues in enzyme-saxagliptin complex formation.

Protein science : a publication of the Protein Society 20080201

Cocrystallization of adamantane-1,3-dicarboxylic acid and 4,4'-bipyridine.

Acta crystallographica. Section C, Crystal structure communications 20080201

Metal atoms collinear with the spiro carbon of 6,6-open adducts, M2@C80(Ad) (M = La and Ce, Ad = adamantylidene).

Journal of the American Chemical Society 20080130

Formation of supramolecular isomers; poly[2]rotaxane and supramolecular assembly.

Chemical communications (Cambridge, England) 20080128

Addition of adamantylidene to La2@C78: isolation and single-crystal X-ray structural determination of the monoadducts.

Journal of the American Chemical Society 20080123

Is adamantane a suitable substituent to pre-organize the acid orientation in E-selectin antagonists?

Bioorganic & medicinal chemistry 20080115

Diastereomerically enriched analogues of the water-soluble phosphine PTA. Synthesis of phenyl(1,3,5-triaza-7-phosphatricyclo[3.3.1.1(3,7)]dec-6-yl)methanol (PZA) and the sulfide PZA(S) and X-ray crystal structures of the oxide PZA(O) and [Cp*IrCl(2)(PZA)].

Inorganic chemistry 20080107

Water-soluble and stable dinitrogen phosphine complexes trans-[ReCl(N2)(PTA-H)n(PTA)4-n]n+ (n = 0-4), the first with 1,3,5-triaza-7-phosphaadamantane.

Dalton transactions (Cambridge, England : 2003) 20080107

The dipeptidyl peptidase-4 inhibitor vildagliptin improves beta-cell function and insulin sensitivity in subjects with impaired fasting glucose.

Diabetes care 20080101

Characterization of the influence of vildagliptin on model-assessed -cell function in patients with type 2 diabetes and mild hyperglycemia.

The Journal of clinical endocrinology and metabolism 20080101

Medical management of influenza infection.

Annual review of medicine 20080101

Effects of the dipeptidyl peptidase-IV inhibitor vildagliptin on incretin hormones, islet function, and postprandial glycemia in subjects with impaired glucose tolerance.

Diabetes care 20080101

Vildagliptin, a novel dipeptidyl peptidase IV inhibitor, has no pharmacokinetic interactions with the antihypertensive agents amlodipine, valsartan, and ramipril in healthy subjects.

Journal of clinical pharmacology 20080101

Efficacy and tolerability of vildagliptin vs. pioglitazone when added to metformin: a 24-week, randomized, double-blind study.

Diabetes, obesity & metabolism 20080101

Diamonds are a chemist's best friend: diamondoid chemistry beyond adamantane.

Angewandte Chemie (International ed. in English) 20080101

Update: vildagliptin for the treatment of Type 2 diabetes.

Expert opinion on investigational drugs 20080101

A chiral pool based synthesis of platensimycin.

Angewandte Chemie (International ed. in English) 20080101

Cross-clade protective immune responses to influenza viruses with H5N1 HA and NA elicited by an influenza virus-like particle.

PloS one 20080101

Adamantane-resistant influenza infection during the 2004-05 season.

Emerging infectious diseases 20080101

The evolution of human influenza A viruses from 1999 to 2006: a complete genome study.

Virology journal 20080101

Synthesis of platensimycin.

Angewandte Chemie (International ed. in English) 20080101

Platensimycin: a promising antimicrobial targeting fatty acid synthesis.

Current medicinal chemistry 20080101

Anticonvulsant sulfonamides/sulfamates/sulfamides with carbonic anhydrase inhibitory activity: drug design and mechanism of action.

Current pharmaceutical design 20080101

[Effects of hemantane on the main subtypes of dopamine receptors in the rat striatum ex vivo].

Eksperimental'naia i klinicheskaia farmakologiia 20080101

High-relaxivity magnetic resonance imaging (MRI) contrast agent based on supramolecular assembly between a gadolinium chelate, a modified dextran, and poly-beta-cyclodextrin.

Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

A carbonyl ylide cycloaddition approach to platensimycin.

Angewandte Chemie (International ed. in English) 20080101

Novel Anticancer Platinum(IV) Complexes with Adamantylamine: Their Efficiency and Innovative Chemotherapy Strategies Modifying Lipid Metabolism.

Metal-based drugs 20080101

Impact of emerging antiviral drug resistance on influenza containment and spread: influence of subclinical infection and strategic use of a stockpile containing one or two drugs.

PloS one 20080101

The metabolism and transplacental transfer of oseltamivir in the ex vivo human model.

Infectious diseases in obstetrics and gynecology 20080101

[The possibilities of using himantane in the treatment of Parkinson's disease].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101

High-pressure entry into platencin.

Angewandte Chemie (International ed. in English) 20080101

New anti-tuberculosis drugs with novel mechanisms of action.

Current medicinal chemistry 20080101

Substituted 1,3,5-triazaadamantanes: biocompatible and degradable building blocks.

Angewandte Chemie (International ed. in English) 20080101

Beta-cyclodextrin-appended giant amphiphile: aggregation to vesicle polymersomes and immobilisation of enzymes.

Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

[Blockade of the alpha3alpha4 N-cholinoreceptors and GluR1 AMPA receptors eliminates clonic-tonic nicotinic and kainate seizures].

Eksperimental'naia i klinicheskaia farmakologiia 20080101

[Characteristics of ladasten effect in neurasthenia patients with various EEG parameters].

Eksperimental'naia i klinicheskaia farmakologiia 20080101

Neuraminidase activity provides a practical read-out for a high throughput influenza antiviral screening assay.

Virology journal 20080101

Molecular characterization of highly pathogenic H5N1 avian influenza viruses isolated in Sweden in 2006.

Virology journal 20080101

Chemical bonding in the inclusion complex of he in adamantane (He@adam): the origin of the barrier to dissociation.

Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

Chemical bonding in the inclusion complex of He in adamantane, He@adam: antithesis and complement.

Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

Vildagliptin: a review of its use in the management of type 2 diabetes mellitus.

Drugs 20080101

Surveillance of adamantane resistance among influenza A H3 viruses isolated in Argentina between 2001 and 2007.

Revista Argentina de microbiologia 20080101

Medicinal chemistry approaches to the inhibition of dipeptidyl peptidase IV.

Current topics in medicinal chemistry 20080101

[Antiviral activity of polycarboxylic substances modified by cage hydrocarbon and sulfoacid pharmacophors against cytomegalovirus infection in vitro].

Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20080101

S-2-(Adamant-1-yl)-4-methyl-phenyl N,N-dimethyl-thio-carbamate.

Acta crystallographica. Section E, Structure reports online 20080101

Sulphonylureas induced vasorelaxation of mouse arteries.

European journal of pharmacology 20071222

Biosynthetic studies of platensimycin.

Journal of the American Chemical Society 20071219

Nuclear spin dynamics using time-dependent projection operators: application to the saturation of dipolar order in slowly rotating samples.

The Journal of chemical physics 20071214

Total synthesis and antibacterial properties of carbaplatensimycin.

Journal of the American Chemical Society 20071205

[Two breakthroughs in the treatment of type 2 diabetes. Both the receptor agonist and enzyme inhibitors now available in the clinic].

Lakartidningen 20071205

Soluble epoxide hydrolase: a novel therapeutic target in stroke.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20071201

Incretin receptors for glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide are essential for the sustained metabolic actions of vildagliptin in mice.

Diabetes 20071201

Epoxyeicosatrienoic acids regulate Trp channel dependent Ca2+ signaling and hyperpolarization in endothelial cells.

Arteriosclerosis, thrombosis, and vascular biology 20071201

Management of type 2 diabetes in treatment-naive elderly patients: benefits and risks of vildagliptin monotherapy.

Diabetes care 20071201

Activity of artemether and OZ78 against triclabendazole-resistant Fasciola hepatica.

Transactions of the Royal Society of Tropical Medicine and Hygiene 20071201

Evaluation of the potential for steady-state pharmacokinetic interaction between vildagliptin and simvastatin in healthy subjects.

Current medical research and opinion 20071201

Mapping of cytochrome P450 2B4 substrate binding sites by photolabile probe 3-azidiamantane: identification of putative substrate access regions.

Archives of biochemistry and biophysics 20071201

Pandemic flu vaccine: are we doing enough?

Clinical pharmacology and therapeutics 20071201

Pressure perturbation calorimetry, heat capacity and the role of water in protein stability and interactions.

Biochemical Society transactions 20071201

DPP-4 inhibitors.

Best practice & research. Clinical endocrinology & metabolism 20071201

Clinical management strategies for type 2 diabetes.

JAAPA : official journal of the American Academy of Physician Assistants 20071201

New treatments for type 2 diabetes--the DPP4 inhibitors.

Primary care diabetes 20071201

Discovery of potent and selective adamantane-based small-molecule P2X(7) receptor antagonists/interleukin-1beta inhibitors.

Journal of medicinal chemistry 20071129

2-phenylimidazopyridines, a new series of Golgi compounds with potent antiviral activity.

Journal of medicinal chemistry 20071129

Stable organic azides based on rigid tetrahedral methane and adamantane structures as high energetic materials.

Organic & biomolecular chemistry 20071121

An artificial molecular chaperone: poly-pseudo-rotaxane with an extensible axle.

Journal of the American Chemical Society 20071121

Supramolecular interactions between beta-cyclodextrin and hydrophobically end-capped poly(ethylene glycol)s: a quartz crystal microbalance study.

Journal of colloid and interface science 20071115

Evaluation of some adamantane-based synthetic trioxanes against Plasmodium knowlesi in rhesus monkeys.

Life sciences 20071110

An effective enantioselective route to the platensimycin core.

Organic letters 20071108

Investigation of the gas phase reactivity of the 1-adamantyl radical using a distonic radical anion approach.

Organic & biomolecular chemistry 20071107

Iron-mediated degradation kinetics of substituted dispiro-1,2,4-trioxolane antimalarials.

Journal of pharmaceutical sciences 20071101

The dipeptidyl peptidase 4 inhibitor vildagliptin does not accentuate glibenclamide-induced hypoglycemia but reduces glucose-induced glucagon-like peptide 1 and gastric inhibitory polypeptide secretion.

The Journal of clinical endocrinology and metabolism 20071101

Advances in the treatment of tuberculosis.

Clinical pharmacology and therapeutics 20071101

Improved meal-related insulin processing contributes to the enhancement of B-cell function by the DPP-4 inhibitor vildagliptin in patients with type 2 diabetes.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20071101

1,3-disubstituted ureas functionalized with ether groups are potent inhibitors of the soluble epoxide hydrolase with improved pharmacokinetic properties.

Journal of medicinal chemistry 20071018

DPP-4 inhibition improves glucose tolerance and increases insulin and GLP-1 responses to gastric glucose in association with normalized islet topography in mice with beta-cell-specific overexpression of human islet amyloid polypeptide.

Regulatory peptides 20071004

Precision and sensitivity optimization of quantitative measurements in solid state NMR.

Journal of magnetic resonance (San Diego, Calif. : 1997) 20071001

The effects of ladasten on dopaminergic neurotransmission and hippocampal synaptic plasticity in rats.

Neuropharmacology 20071001

Creating a model program for influenza surveillance in California: results from the 2005-2006 influenza season.

American journal of preventive medicine 20071001

Viral evolution in the genomic age.

PLoS biology 20071001

Analysis of vasodilator responses to peroxynitrite in the hindlimb vascular bed of the cat.

Journal of cardiovascular pharmacology 20071001

Clonorchicidal properties of the synthetic trioxolane OZ78.

The Journal of parasitology 20071001

GLP-1-based therapy of type 2 diabetes: GLP-1 mimetics and DPP-IV inhibitors.

Current diabetes reports 20071001

Scanning electron microscopy of nanoscale chemical patterns.

ACS nano 20071001

alpha-selective sialylations at -78 degrees C in nitrile solvents with a 1-adamantanyl thiosialoside.

The Journal of organic chemistry 20070928

Enantioselective synthesis of (-)-platensimycin oxatetracyclic core by using an intramolecular Diels-Alder reaction.

Organic letters 20070927

1-Adamantanethiolate monolayer displacement kinetics follow a universal form.

Journal of the American Chemical Society 20070905

Comparison between vildagliptin and metformin to sustain reductions in HbA(1c) over 1 year in drug-naïve patients with Type 2 diabetes.

Diabetic medicine : a journal of the British Diabetic Association 20070901

Dose proportionality and the effect of food on vildagliptin, a novel dipeptidyl peptidase IV inhibitor, in healthy volunteers.

Journal of clinical pharmacology 20070901

Antitumor activity of the combination of synthetic retinoid ST1926 and cisplatin in ovarian carcinoma models.

Annals of oncology : official journal of the European Society for Medical Oncology 20070901

Diffuse scattering from large-angle, thermally induced, orientational disorder in molecular crystals.

Acta crystallographica. Section A, Foundations of crystallography 20070901

The DPP-4 inhibitor vildagliptin: robust glycaemic control in type 2 diabetes and beyond.

Diabetes, obesity & metabolism 20070901

Characterization and alkane oxidation activity of a diastereopure seven-coordinate iron(III) alkylperoxo complex.

Dalton transactions (Cambridge, England : 2003) 20070821

New tuberculosis therapeutics: a growing pipeline.

The Journal of infectious diseases 20070815

Tracking 'invisible' alkylchlorocarbenes by their sigma --> p absorptions: dynamics and solvent interactions.

Journal of the American Chemical Society 20070815

Orally bioavailable potent soluble epoxide hydrolase inhibitors.

Journal of medicinal chemistry 20070809

Enantioselective route to platensimycin: an intramolecular Robinson annulation approach.

Journal of the American Chemical Society 20070808

Guest recognition with micelle-bound cavitands.

Journal of the American Chemical Society 20070808

The emergence of adamantane resistance in influenza A(H1) viruses in Australia and regionally in 2006.

Antiviral research 20070801

The genesis and spread of reassortment human influenza A/H3N2 viruses conferring adamantane resistance.

Molecular biology and evolution 20070801

Cholecystokinin CCK2 receptors mediate the peptide's inhibitory actions on the contractile activity of human distal colon via the nitric oxide pathway.

British journal of pharmacology 20070801

Design and synthesis of bioactive adamantane spiro heterocycles.

Bioorganic & medicinal chemistry letters 20070801

Dipeptidyl peptidase 4 inhibition and vildagliptin therapy for type 2 diabetes.

International journal of clinical practice. Supplement 20070801

Dipeptidyl peptidase IV inhibitors and the incretin system in type 2 diabetes mellitus.

Pharmacotherapy 20070801

Evaluation of pharmacokinetic interactions between vildagliptin and digoxin in healthy volunteers.

Journal of clinical pharmacology 20070801

Oxidation of some cage hydrocarbons by dioxiranes. Nature of the transition structure for the reaction of C-H bonds with dimethyldioxirane: a comparison of B3PW91 density functional theory with experiment.

Organic & biomolecular chemistry 20070721

Surveillance of resistance to adamantanes among influenza A(H3N2) and A(H1N1) viruses isolated worldwide.

The Journal of infectious diseases 20070715

Efficacy and safety of incretin therapy in type 2 diabetes: systematic review and meta-analysis.

JAMA 20070711

Direct stereocontrolled synthesis of 3-amino-3-deoxy-beta-mannopyranosides: importance of the nitrogen protecting group on stereoselectivity.

The Journal of organic chemistry 20070706

Electrosynthetic reduction of 1-iodoadamantane forming 1,1'-biadamantane and adamantane in aprotic solvents: insonation switches the mechanism from dimerisation to exclusive monomer formation.

Ultrasonics sonochemistry 20070701

Synthesis and anti-HIV studies of 2-adamantyl-substituted thiazolidin-4-ones.

European journal of medicinal chemistry 20070701

Increasing or stabilizing renal epoxyeicosatrienoic acid production attenuates abnormal renal function and hypertension in obese rats.

American journal of physiology. Renal physiology 20070701

Effective switch-on fluorescence sensing of zinc(II) ion by 8-aminoquinolino-beta-cyclodextrin/adamantaneacetic acid system in water.

Bioorganic & medicinal chemistry 20070701

The influence of hepatic impairment on the pharmacokinetics of the dipeptidyl peptidase IV (DPP-4) inhibitor vildagliptin.

European journal of clinical pharmacology 20070701

[New concepts in the treatment of type 2 diabetes].

Der Internist 20070701

Mining and engineering natural-product biosynthetic pathways.

Nature chemical biology 20070701

Inclusion complexes of cyclodextrins with biradicals linked by a polyether chain--an EPR study.

Organic & biomolecular chemistry 20070621

Proteomic analysis identifies oxidative stress induction by adaphostin.

Clinical cancer research : an official journal of the American Association for Cancer Research 20070615

Combination of dipeptidylpeptidase IV inhibitor and low dose thiazolidinedione: preclinical efficacy and safety in db/db mice.

Life sciences 20070613

An expedient enantioselective strategy for the oxatetracyclic core of platensimycin.

Organic letters 20070607

Dipeptidyl peptidase-4 inhibitors: clinical data and clinical implications.

Diabetes care 20070601

Inhibition of KATP channels in the rat tail artery by neurally released noradrenaline acting on postjunctional alpha2-adrenoceptors.

The Journal of physiology 20070601

Addition of vildagliptin to insulin improves glycaemic control in type 2 diabetes.

Diabetologia 20070601

Tailored slice selection in solid-state MRI by DANTE under magic-echo line narrowing.

Journal of magnetic resonance (San Diego, Calif. : 1997) 20070601

Which patients are candidates for dipeptidyl peptidase IV inhibitors?

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070601

Vildagliptin: a novel oral therapy for type 2 diabetes mellitus.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070601

An adamantyl-substituted retinoid-derived molecule that inhibits cancer cell growth and angiogenesis by inducing apoptosis and binds to small heterodimer partner nuclear receptor: effects of modifying its carboxylate group on apoptosis, proliferation, and protein-tyrosine phosphatase activity.

Journal of medicinal chemistry 20070531

Gas-phase diastereoselectivity of secondary 5-substituted (X)-adamant-2-yl (X = F, Si(CH(3))(3)) cations.

The Journal of organic chemistry 20070525

New treatments for diabetes.

The New England journal of medicine 20070524

Preparation of novel fluoroalkyl-end-capped 2-acrylamido-2-methylpropanesulfonic acid cooligomeric nanoparticles containing adamantane units possessing a lower critical solution temperature characteristic in organic media.

Langmuir : the ACS journal of surfaces and colloids 20070522

Formal synthesis of (+/-)-platensimycin.

Chemical communications (Cambridge, England) 20070521

Discovery and biological evaluation of adamantyl amide 11beta-HSD1 inhibitors.

Bioorganic & medicinal chemistry letters 20070515

Synthesis and structures of bis(dithiolene)tungsten(IV,VI) thiolate and selenolate complexes: approaches to the active sites of molybdenum and tungsten formate dehydrogenases.

Inorganic chemistry 20070514

Dipeptidyl peptidase 8/9-like activity in human leukocytes.

Journal of leukocyte biology 20070501

Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity.

Diabetes 20070501

Vitamin D3 derivatives with adamantane or lactone ring side chains are cell type-selective vitamin D receptor modulators.

Molecular pharmacology 20070501

Sinaicinone, a complex adamantanyl derivative from Hypericum sinaicum.

Phytochemistry 20070501

Pharmacodynamics of vildagliptin in patients with type 2 diabetes during OGTT.

Journal of clinical pharmacology 20070501

The role of vildagliptin in the management of type 2 diabetes mellitus.

The Annals of pharmacotherapy 20070501

Pathologically-activated therapeutics for neuroprotection: mechanism of NMDA receptor block by memantine and S-nitrosylation.

Current drug targets 20070501

Effect of the novel oral dipeptidyl peptidase IV inhibitor vildagliptin on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects.

Current medical research and opinion 20070501

Heterogeneity of thylakoid membranes studied by EPR spin probe.

Biochemistry. Biokhimiia 20070501

Formal synthesis of (+/-)-platensimycin.

Organic letters 20070426

Identification of a highly potent vitamin D receptor antagonist: (25S)-26-adamantyl-25-hydroxy-2-methylene-22,23-didehydro-19,27-dinor-20-epi-vitamin D3 (ADMI3).

Archives of biochemistry and biophysics 20070415

Novel amidino-substituted benzimidazoles: synthesis of compounds and inhibition of dipeptidyl peptidase III.

Bioorganic chemistry 20070401

Efficacy and tolerability of vildagliptin monotherapy in drug-naïve patients with type 2 diabetes.

Diabetes research and clinical practice 20070401

Drug therapy of experimental tuberculosis (TB): improved outcome by combining SQ109, a new diamine antibiotic, with existing TB drugs.

Antimicrobial agents and chemotherapy 20070401

The dipeptidyl peptidase IV inhibitor vildagliptin suppresses endogenous glucose production and enhances islet function after single-dose administration in type 2 diabetic patients.

The Journal of clinical endocrinology and metabolism 20070401

Effects of vildagliptin on glucose control over 24 weeks in patients with type 2 diabetes inadequately controlled with metformin.

Diabetes care 20070401

[Incretin enhancers, incretin mimetics: from therapeutic concept to clinical application].

Orvosi hetilap 20070401

Antiviral therapy and prophylaxis for influenza in children.

Pediatrics 20070401

Inhibition of DPP-4: a new therapeutic approach for the treatment of type 2 diabetes.

Current medical research and opinion 20070401

Influenza: evolving strategies in treatment and prevention.

Seminars in respiratory and critical care medicine 20070401

[Glucagon-like peptide-1 (GLP-1), new target for the treatment of type 2 diabetes].

Revue medicale de Liege 20070401

Memantine: efficacy and safety in mild-to-severe Alzheimer's disease.

Neuropsychiatric disease and treatment 20070401

Inhibition of mitochondrial respiration as a source of adaphostin-induced reactive oxygen species and cytotoxicity.

The Journal of biological chemistry 20070323

Hierarchical chiral framework based on a rigid adamantane tripod on Au(111).

Journal of the American Chemical Society 20070307

Amperometric biosensor for xanthine with supramolecular architecture.

Chemical communications (Cambridge, England) 20070307

Adaphostin cytoxicity in glioblastoma cells is ROS-dependent and is accompanied by upregulation of heme oxygenase-1.

Cancer chemotherapy and pharmacology 20070301

Susceptibility of highly pathogenic A(H5N1) avian influenza viruses to the neuraminidase inhibitors and adamantanes.

Antiviral research 20070301

The novel atypical retinoid ST1926 is active in ATRA resistant neuroblastoma cells acting by a different mechanism.

Biochemical pharmacology 20070301

3-[2-((2S)-2-cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-3-methyl-butyramide analogues as selective DPP-IV inhibitors for the treatment of type-II diabetes.

Bioorganic & medicinal chemistry letters 20070301

Different target range and cytotoxic specificity of adaphostin and 17-allylamino-17-demethoxygeldanamycin in imatinib-resistant and sensitive cell lines.

Leukemia 20070301

Vildagliptin in combination with pioglitazone improves glycaemic control in patients with type 2 diabetes failing thiazolidinedione monotherapy: a randomized, placebo-controlled study.

Diabetes, obesity & metabolism 20070301

Efficacy and tolerability of initial combination therapy with vildagliptin and pioglitazone compared with component monotherapy in patients with type 2 diabetes.

Diabetes, obesity & metabolism 20070301

Vildagliptin in drug-naïve patients with type 2 diabetes: a 24-week, double-blind, randomized, placebo-controlled, multiple-dose study.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20070301

Study of the complexation of different methacrylates with cyclodextrins employing a combination of electrophoretic, chromatographic, and NMR-spectroscopic methods.

Journal of separation science 20070301

New strain of influenza A virus (H5N1), Thailand.

Emerging infectious diseases 20070301

[Involvement of ionotropic glutamate receptors in the genesis of arecoline-induced tremor].

Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20070301

Influenza infection and COPD.

International journal of chronic obstructive pulmonary disease 20070301

CCK2 receptors mediate inhibitory effects of cholecystokinin on the motor activity of guinea-pig distal colon.

European journal of pharmacology 20070227

Up-regulation of c-Jun inhibits proliferation and induces apoptosis via caspase-triggered c-Abl cleavage in human multiple myeloma.

Cancer research 20070215

New adamantane-based spiro 1,2,4-trioxanes orally effective against rodent and simian malaria.

Journal of medicinal chemistry 20070208

Increased adamantane resistance in influenza A(H3) viruses in Australia and neighbouring countries in 2005.

Antiviral research 20070201

Functional selectivity of dopamine D1 receptor agonists in regulating the fate of internalized receptors.

Neuropharmacology 20070201

Discovery of adamantane ethers as inhibitors of 11beta-HSD-1: Synthesis and biological evaluation.

Bioorganic & medicinal chemistry letters 20070201

Influence of an additional 2-amino substituent of the 1-aminoethyl pharmacophore group on the potency of rimantadine against influenza virus A.

Bioorganic & medicinal chemistry letters 20070201

Synthesis, antimicrobial, and anti-inflammatory activities of novel 2-(1-adamantyl)-5-substituted-1,3,4-oxadiazoles and 2-(1-adamantylamino)-5-substituted-1,3,4-thiadiazoles.

European journal of medicinal chemistry 20070201

Comparison of vildagliptin and rosiglitazone monotherapy in patients with type 2 diabetes: a 24-week, double-blind, randomized trial.

Diabetes care 20070201

Gliptins.

Lancet (London, England) 20070127

The reversible binding of anti-human serum albumin to poly beta-cyclodextrin-coated porous silica supports.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070115

Adamantane sulfone and sulfonamide 11-beta-HSD1 Inhibitors.

Bioorganic & medicinal chemistry letters 20070115

Synthesis, anti-tuberculosis activity, and 3D-QSAR study of 4-(adamantan-1-yl)-2-substituted quinolines.

Bioorganic & medicinal chemistry 20070115

Isofagomine- and 2,5-anhydro-2,5-imino-D-glucitol-based glucocerebrosidase pharmacological chaperones for Gaucher disease intervention.

Journal of medicinal chemistry 20070111

Discovery and metabolic stabilization of potent and selective 2-amino-N-(adamant-2-yl) acetamide 11beta-hydroxysteroid dehydrogenase type 1 inhibitors.

Journal of medicinal chemistry 20070111

Supramolecular control of unwinding and rewinding of a double helix of oligoresorcinol using cyclodextrin/adamantane system.

Journal of the American Chemical Society 20070110

Selective blockade of Ca2+ permeable AMPA receptors in CA1 area of rat hippocampus.

Neuroscience 20070105

Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase.

Bioorganic & medicinal chemistry 20070101

Liraglutide, a long-acting glucagon-like peptide-1 analog, reduces body weight and food intake in obese candy-fed rats, whereas a dipeptidyl peptidase-IV inhibitor, vildagliptin, does not.

Diabetes 20070101

Vildagliptin does not affect C-peptide clearance in patients with type 2 diabetes.

Journal of clinical pharmacology 20070101

Adamantyl-substituted retinoid-related molecules bind small heterodimer partner and modulate the Sin3A repressor.

Cancer research 20070101

Antiviral resistance and the control of pandemic influenza.

PLoS medicine 20070101

Controlling the association of adamantyl-substituted poly{N-[tris(hydroxymethyl)methyl]acrylamide} and a beta-cyclodextrin/epichlorohydrin polymer by a small drug molecule--naproxen.

Chemistry & biodiversity 20070101

Physicochemical and biological characterization of targeted, nucleic acid-containing nanoparticles.

Bioconjugate chemistry 20070101

Cyclodextrin complexes of polymers bearing adamantyl groups: host-guest interactions and the effect of spacers on water solubility.

Angewandte Chemie (International ed. in English) 20070101

Chemiluminescent determination of leukocyte alkaline phosphatase: an advantageous alternative to the cytochemical assay.

Journal of clinical laboratory analysis 20070101

Asymmetric total syntheses of platensimycin.

Angewandte Chemie (International ed. in English) 20070101

Adamantaplatensimycin: a bioactive analogue of platensimycin.

Angewandte Chemie (International ed. in English) 20070101

Molecular probes for P2X7 receptor studies.

Current medicinal chemistry 20070101

Pharmacokinetics and pharmacodynamics of vildagliptin in patients with type 2 diabetes mellitus.

Clinical pharmacokinetics 20070101

Lower-rim substituted calixarenes and their applications.

Bioinorganic chemistry and applications 20070101

A hydrophilic cyclodextrin duplex forming supramolecular assemblies by physical cross-linking of a biopolymer.

Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

The absolute oral bioavailability and population-based pharmacokinetic modelling of a novel dipeptidylpeptidase-IV inhibitor, vildagliptin, in healthy volunteers.

Clinical pharmacokinetics 20070101

Protecting-group-free formal synthesis of platensimycin.

Angewandte Chemie (International ed. in English) 20070101

On the ease of predicting the thermodynamic properties of beta-cyclodextrin inclusion complexes.

Chemistry Central journal 20070101

[The acute and subchronic effects of hemantane on [3H]-dopamine reuptake in rat striatal synaptosomes ex vivo].

Eksperimental'naia i klinicheskaia farmakologiia 20070101

[Antimicrobial effect of 4-(adamantyl-1)-1-(1-aminobutyl)benzol].

Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) 20070101

Synthesis of 1-{4-[4-(adamant-1-yl)phenoxymethyl]-2-(4-bromophenyl)- 1,3-dioxolan-2-ylmethyl}imidazole with expected antifungal and antibacterial activity.

Acta poloniae pharmaceutica 20070101

[Carboxy mimetic derivatives of nucleic acid polymeric backbones inhibiting human cytomegalovirus. 1. In vitro microbicidal effect].

Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20070101

Small organic compounds enhance antigen loading of class II major histocompatibility complex proteins by targeting the polymorphic P1 pocket.

The Journal of biological chemistry 20061215

Molecular mechanism of adaphostin-mediated G1 arrest in prostate cancer (PC-3) cells: signaling events mediated by hepatocyte growth factor receptor, c-Met, and p38 MAPK pathways.

The Journal of biological chemistry 20061208

Chemoselective protection of solid-phase compatible Fmoc-phosphinic building blocks.

The Journal of organic chemistry 20061208

In vitro biological efficiency of tenocyclidine-TCP and its adamantane derivative TAMORF.

Toxicology in vitro : an international journal published in association with BIBRA 20061201

7-But-2-ynyl-9-(6-methoxy-pyridin-3-yl)-6-piperazin-1-yl-7,9-dihydro-purin-8-one is a novel competitive and selective inhibitor of dipeptidyl peptidase IV with an antihyperglycemic activity.

The Journal of pharmacology and experimental therapeutics 20061201

Adamantane 11-beta-HSD-1 inhibitors: Application of an isocyanide multicomponent reaction.

Bioorganic & medicinal chemistry letters 20061201

The synthetic peroxide OZ78 is effective against Echinostoma caproni and Fasciola hepatica.

The Journal of antimicrobial chemotherapy 20061201

Dipeptidyl peptidase IV (DPP IV) inhibitors: A newly emerging drug class for the treatment of type 2 diabetes.

Diabetes & vascular disease research 20061201

The use of derivatized cyclodextrins as solubilizing agents in the preparation of macroporous polymers employed as amphiphilic continuous beds in capillary electrochromatography.

Journal of separation science 20061201

The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes.

Lancet (London, England) 20061111

Self-organization-induced three-dimensional honeycomb pattern in structure-controlled bulky methacrylate polymers: Synthesis, morphology, and mechanism of pore formation.

The journal of physical chemistry. B 20061102

A nonfeminizing estrogen analog protects against ethanol withdrawal toxicity in immortalized hippocampal cells.

The Journal of pharmacology and experimental therapeutics 20061101

Molecular aspects of antitumor effects of a new platinum(IV) drug.

Molecular pharmacology 20061101

DPP-4 inhibitors and their potential role in the management of type 2 diabetes.

International journal of clinical practice 20061101

Disease modifying therapy for AD?

Journal of neurochemistry 20061101

How do different GLP-1 mimetics differ in their actions?

Current diabetes reports 20061101

Exenatide: a novel approach for treatment of type 2 diabetes.

Southern medical journal 20061101

Total synthesis of platensimycin.

Angewandte Chemie (International ed. in English) 20061027

Dirhodium tetracarboxylates derived from adamantylglycine as chiral catalysts for enantioselective C-h aminations.

Organic letters 20061026

Metabolic mimics: thiol responsive drug release.

Journal of colloid and interface science 20061015

Synthesis and structural activity relationship of 11beta-HSD1 inhibitors with novel adamantane replacements.

Bioorganic & medicinal chemistry letters 20061015

Synthesis and biological evaluation of heterocycle containing adamantane 11beta-HSD1 inhibitors.

Bioorganic & medicinal chemistry letters 20061015

Peptidyl-urea based inhibitors of soluble epoxide hydrolases.

Bioorganic & medicinal chemistry letters 20061015

Detection of multiple-quantum coherences with projective nuclear magnetic resonance measurement.

The Journal of chemical physics 20061014

Shift shown in influenza A adamantane resistance.

JAMA 20061004

Shift shown in influenza A adamantane resistance.

JAMA 20061004

Syntheses, characterization, and catalytic ability in alkane oxygenation of chloro(dimethyl sulfoxide)ruthenium(II) complexes with tris(2-pyridylmethyl)amine and its derivatives.

Inorganic chemistry 20061002

Adaphostin and bortezomib induce oxidative injury and apoptosis in imatinib mesylate-resistant hematopoietic cells expressing mutant forms of Bcr/Abl.

Leukemia research 20061001

Synthesis, conformational characteristics and anti-influenza virus A activity of some 2-adamantylsubstituted azacycles.

Bioorganic chemistry 20061001

3-Methylglutaric acid as a 13C solid-state NMR standard.

Solid state nuclear magnetic resonance 20061001

Macromolecular assemblies based on coupled inclusion complex and electrostatic interactions.

Biomacromolecules 20061001

Resistance to anti-influenza drugs: adamantanes and neuraminidase inhibitors.

Expert review of anti-infective therapy 20061001

Attachment of streptavidin to beta-cyclodextrin molecular printboards via orthogonal host-guest and protein-ligand interactions.

Small (Weinheim an der Bergstrasse, Germany) 20061001

C-glycoside clustering on calix[4]arene, adamantane, and benzene scaffolds through 1,2,3-triazole linkers.

The Journal of organic chemistry 20060929

Oxaza adamantyl cannabinoids. A new class of cannabinoid receptor probes.

The Journal of organic chemistry 20060929

Supramolecular assembly of cyclodextrin-based nanoparticles on solid surfaces for gene delivery.

Langmuir : the ACS journal of surfaces and colloids 20060926

Effect of dopamine D1 receptor antagonist SCH23390 and D1 agonist A77636 on active allothetic place avoidance, a spatial cognition task.

Behavioural brain research 20060925

Supramolecular complexes of spin-labelled cyclodextrins.

Organic & biomolecular chemistry 20060921

Forensic fingerprinting of diamondoids for correlation and differentiation of spilled oil and petroleum products.

Environmental science & technology 20060915

Isolation, structure, and absolute stereochemistry of platensimycin, a broad spectrum antibiotic discovered using an antisense differential sensitivity strategy.

Journal of the American Chemical Society 20060913

Substituted adamantyl-urea inhibitors of the soluble epoxide hydrolase dilate mesenteric resistance vessels.

The Journal of pharmacology and experimental therapeutics 20060901

Antitumor activity of the retinoid-related molecules (E)-3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid (ST1926) and 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) in F9 teratocarcinoma: Role of retinoic acid receptor gamma and retinoid-independent pathways.

Molecular pharmacology 20060901

Vildagliptin therapy reduces postprandial intestinal triglyceride-rich lipoprotein particles in patients with type 2 diabetes.

Diabetologia 20060901

Adaphostin has significant and selective activity against chronic and acute myeloid leukemia cells.

Cancer science 20060901

[Development of environmentally benign oxidations using hypervalent iodine (III) reagents].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20060901

Platensimycin, a new antibiotic and 'superbug challenger' from nature.

ChemMedChem 20060901

Oral agents for type 2 diabetes reduce HbA1c, are weight neutral.

Geriatrics 20060901

Material surfaces and MRSA.

Medical device technology 20060901

Modeling competitive guest binding to beta-cyclodextrin molecular printboards.

The journal of physical chemistry. B 20060824

Amide-substituted farnesylcysteine analogs as inhibitors of human isoprenylcysteine carboxyl methyltransferase.

Bioorganic & medicinal chemistry letters 20060815

Multilayer films based on host-guest interactions between biocompatible polymers.

Chemical communications (Cambridge, England) 20060814

Synthesis, structures, and olefin polymerization capability of vanadium(4+) imido compounds with fac-N3 donor ligands.

Inorganic chemistry 20060807

Dirhodium tetracarboxylate derived from adamantylglycine as a chiral catalyst for carbenoid reactions.

Organic letters 20060803

Synergistic interactions of SQ109, a new ethylene diamine, with front-line antitubercular drugs in vitro.

The Journal of antimicrobial chemotherapy 20060801

American Diabetes Association--66th scientific sessions. 9-13 June 2006, Washington, DC, USA.

IDrugs : the investigational drugs journal 20060801

Improving potency, selectivity, and water solubility of adenosine A1 receptor antagonists: xanthines modified at position 3 and related pyrimido[1,2,3-cd]purinediones.

ChemMedChem 20060801

Vildagliptin: a novel DPP-4 inhibitor with pancreatic islet enhancement activity for treatment of patients with type 2 diabetes.

Drugs of today (Barcelona, Spain : 1998) 20060801

Directed assembly and separation of self-assembled monolayers via electrochemical processing.

The journal of physical chemistry. B 20060727

One-pot synthesis of metal primary phosphine complexes from O=PCl2R or PCl2R. Isolation and characterization of primary alkylphosphine complexes of a metalloporphyrin.

Inorganic chemistry 20060724

Reaction of thioketones with propiolic acids.

Organic & biomolecular chemistry 20060721

New lamellar structure formed by an adamantyl derivative of cholic acid.

The journal of physical chemistry. B 20060720

Ab initio and experimental thermodynamic and kinetic study of proton-assisted bond activation in gaseous hydrocarbons: deconvolution of reaction efficiencies in the case of adamantane.

Chemistry (Weinheim an der Bergstrasse, Germany) 20060717

Computational studies of ethynyl- and diethynyl-expanded tetrahedranes, prismanes, cubanes, and adamantanes.

The Journal of organic chemistry 20060707

Reactivity of electrophilic micro-phosphinidene complexes with N-heterocyclic carbenes: formation of the first main group element adducts of 'abnormal' carbene ligands.

Chemical communications (Cambridge, England) 20060705

2-azaadamantane N-oxyl (AZADO) and 1-Me-AZADO: highly efficient organocatalysts for oxidation of alcohols.

Journal of the American Chemical Society 20060705

Regioselective hydroxylation of adamantane by Streptomyces griseoplanus cells.

Applied microbiology and biotechnology 20060701

The first intermediates in the bromination of bicyclo[3.3.1]nonylidenebicyclo[3.3.1]nonane, combination of experiments and theoretical results.

Journal of molecular modeling 20060701

Irt>t schedule controlled behavior in 'learned-helpless' rats: effects from a cannabinoid agonist.

Neuropharmacology 20060701

The pharmacology of aminoadamantane nitrates.

Current Alzheimer research 20060701

[Cytosine demethylation in the tyrosine hydroxylase gene promoter in the hypothalamus cells of the rat brain under the action of an aminoadamantane derivative Ladasten].

Genetika 20060701

Selection between pinching-type and supramolecular polymer-type complexes by alpha-cyclodextrin-beta-cyclodextrin hetero-dimer and hetero-cinnamamide guest dimers.

The Journal of organic chemistry 20060623

Writing with molecules on molecular printboards.

Dalton transactions (Cambridge, England : 2003) 20060621

Fast catalytic hydroxylation of hydrocarbons with ruthenium porphyrins.

Inorganic chemistry 20060612

Single molecular anatomy of solvophobic effects in host-guest interactions based on surface tension using atomic force microscopy.

Physical review letters 20060609

Raman spectroscopy of diamondoids.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060601

Tumor-cell-targeted methionine-enkephalin analogues containing unnatural amino acids: design, synthesis, and in vitro antitumor activity.

Journal of medicinal chemistry 20060601

[Adamantane resistance among influenza A (H3N2) viruses isolated from the mainland of China].

Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 20060601

Twelve-week monotherapy with the DPP-4 inhibitor vildagliptin improves glycemic control in subjects with type 2 diabetes.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20060601

Effects of a neurotensin analogue (PD149163) and antagonist (SR142948A) on the scopolamine-induced deficits in a novel object discrimination task.

Behavioural pharmacology 20060601

Mono- and binuclear complexes of iron(II) and iron(III) with an N4O ligand: synthesis, structures and catalytic properties in alkane oxidation.

Dalton transactions (Cambridge, England : 2003) 20060528

Regulation of Nur77 nuclear export by c-Jun N-terminal kinase and Akt.

Oncogene 20060518

Antibiotic faces uncertain future.

Nature 20060518

Microbiology: antibiotic stops 'ping-pong' match.

Nature 20060518

Platensimycin is a selective FabF inhibitor with potent antibiotic properties.

Nature 20060518

An EPR study of the C-O bond activation of 1,2-epoxybutane by ground-state Al atoms.

The journal of physical chemistry. A 20060504

Design, synthesis, and characterization of conifer-shaped dendritic architectures.

Chemistry (Weinheim an der Bergstrasse, Germany) 20060503

Thermodynamics of formation of host-guest supramolecular polymers.

Journal of the American Chemical Society 20060503

Preclinical pharmacology of the novel antitumor agent adaphostin, a tyrphostin analog that inhibits bcr/abl.

Cancer chemotherapy and pharmacology 20060501

Induction of GDF-15/NAG-1/MIC-1 in human lung carcinoma cells by retinoid-related molecules and assessment of its role in apoptosis.

Cancer biology & therapy 20060501

Small organic molecules that modulate gene transcription.

Drug discovery today 20060501

Molecule of the month. Vildagilptin.

Drug news & perspectives 20060501

A novel adamantane derivative attenuates retinal ischemia-reperfusion damage in the rat retina through sigma1 receptors.

European journal of pharmacology 20060424

A unidirectional energy transfer cascade process in a ruthenium junction self-assembled by alpha- and beta-cyclodextrins.

Journal of the American Chemical Society 20060412

DNA compaction into new DNA vectors based on cyclodextrin polymer: surface enhanced Raman spectroscopy characterization.

Biopolymers 20060405

Synthesis, structure, and bonding of stable dialkylsilaketenimines.

Journal of the American Chemical Society 20060405

Immunosensors for pollutants working in organic media. Study of performances of different tracers with luminescent detection.

Analytical and bioanalytical chemistry 20060401

Diabetes: assessing the pipeline.

Atherosclerosis. Supplements 20060401

The antitumor effect of a novel differentiation inducer, 2, 2-Bis (4-(4-amino-3-hydroxyphenoxy) phenyl) adamantane (DPA), in combinatory therapy on human colon cancer.

International journal of oncology 20060401

Vildagliptin: an inhibitor of dipeptidyl peptidase-4 with antidiabetic properties.

Expert opinion on investigational drugs 20060401

Design, synthesis, and pharmacological characterization of polyamine toxin derivatives: potent ligands for the pore-forming region of AMPA receptors.

ChemMedChem 20060401

Electron paramagnetic resonance study of the mononuclear Al species formed in the reaction of Al atoms and cyclopropylamine at 77 k in an adamantane matrix.

The journal of physical chemistry. A 20060323

Influenza-associated deaths among children.

The New England journal of medicine 20060323

Polymeric self-assembly into micelles and hollow spheres with multiscale cavities driven by inclusion complexation.

Journal of the American Chemical Society 20060322

Bradykinin B2 receptors mediate pulmonary sympathetic afferents induced reflexes in rabbits.

Life sciences 20060320

Adaphostin-induced oxidative stress overcomes BCR/ABL mutation-dependent and -independent imatinib resistance.

Blood 20060315

The butterfly dimer [(tBu3SiO)Cr]2(mu-OSitBu3)2 and its oxidative cleavage to (tBu3SiO)2Cr(=N-N=CPh2)2 and (tBu3SiO)2Cr=N(2,6-Ph2-C6H3).

Inorganic chemistry 20060306

Ruthenium tetraoxide oxidations of alkanes: DFT calculations of barrier heights and kinetic isotope effects.

The Journal of organic chemistry 20060303

Functional in vitro characterization of CR 3394: a novel voltage dependent N-methyl-D-aspartate (NMDA) receptor antagonist.

Neuropharmacology 20060301

Electron spin relaxation of copper(II) complexes in glassy solution between 10 and 120 K.

Journal of magnetic resonance (San Diego, Calif. : 1997) 20060301

Interspecies pharmacokinetics and in vitro metabolism of SQ109.

British journal of pharmacology 20060301

Controlled synthesis and inclusion ability of a hyaluronic acid derivative bearing beta-cyclodextrin molecules.

Biomacromolecules 20060301

[Dipeptidylpeptidase IV inhibitors and dual action PPAR-agonists].

Medizinische Monatsschrift fur Pharmazeuten 20060301

Drug resistance among influenza A viruses isolated in Italy from 2000 to 2005: are the emergence of Adamantane-resistant viruses cause of concern?

Journal of preventive medicine and hygiene 20060301

The anorectic effect of the selective dopamine D1-receptor agonist A-77636 determined by meal pattern analysis in free-feeding rats.

European journal of pharmacology 20060227

Adamantane resistance among influenza A viruses isolated early during the 2005-2006 influenza season in the United States.

JAMA 20060222

Adamantane resistance in influenza A.

JAMA 20060222

Rigid molecular tripod with an adamantane framework and thiol legs. Synthesis and observation of an ordered monolayer on Au111.

The Journal of organic chemistry 20060217

A novel soluble mimic of the glycolipid, globotriaosyl ceramide inhibits HIV infection.

AIDS (London, England) 20060214

Attenuation of vascular smooth muscle cell proliferation by 1-cyclohexyl-3-dodecyl urea is independent of soluble epoxide hydrolase inhibition.

The Journal of pharmacology and experimental therapeutics 20060201

Multiple-sample probe for solid-state NMR studies of pharmaceuticals.

Solid state nuclear magnetic resonance 20060201

Biocatalytic ammonolysis of (5S)-4,5-dihydro-1H-pyrrole-1,5-dicarboxylic acid, 1-(1,1-dimethylethyl)-5-ethyl ester: preparation of an intermediate to the dipeptidyl peptidase IV inhibitor Saxagliptin.

Bioorganic & medicinal chemistry letters 20060201

Sensitivity considerations in polarization transfer and filtering using dipole-dipole couplings: implications for biomineral systems.

Solid state nuclear magnetic resonance 20060201

Monitoring structural transformations in crystals. 8. Monitoring molecules and a reaction center during a solid-state Yang photocyclization.

Acta crystallographica. Section B, Structural science 20060201

Structural evolution of anionic silicon clusters SiN (20 <or= N <or= 45).

The journal of physical chemistry. A 20060126

High levels of adamantane resistance among influenza A (H3N2) viruses and interim guidelines for use of antiviral agents--United States, 2005-06 influenza season.

MMWR. Morbidity and mortality weekly report 20060120

Peptidic delta opioid receptor agonists produce antidepressant-like effects in the forced swim test and regulate BDNF mRNA expression in rats.

Brain research 20060119

RF9, a potent and selective neuropeptide FF receptor antagonist, prevents opioid-induced tolerance associated with hyperalgesia.

Proceedings of the National Academy of Sciences of the United States of America 20060110

Adaphostin and other anticancer drugs quench the fluorescence of mitochondrial potential probes.

Cell death and differentiation 20060101

The tyrphostin adaphostin interacts synergistically with proteasome inhibitors to induce apoptosis in human leukemia cells through a reactive oxygen species (ROS)-dependent mechanism.

Blood 20060101

Evaluation of antidotal effects of adamantyl derivative Tamorf in soman poisoning.

Journal of applied toxicology : JAT 20060101

Dipeptidyl-peptidase IV converts intact B-type natriuretic peptide into its des-SerPro form.

Clinical chemistry 20060101

The binding interaction of synthetic ozonide antimalarials with natural and modified beta-cyclodextrins.

Journal of pharmaceutical sciences 20060101

Mechanism of Gly-Pro-pNA cleavage catalyzed by dipeptidyl peptidase-IV and its inhibition by saxagliptin (BMS-477118).

Archives of biochemistry and biophysics 20060101

Vaccines and antiviral drugs in pandemic preparedness.

Emerging infectious diseases 20060101

[Thermoprotector properties of a combination of sydnocarb with ladasten].

Eksperimental'naia i klinicheskaia farmakologiia 20060101

Evaluation of transfection protocols for unmodified and modified peptide nucleic acid (PNA) oligomers.

Oligonucleotides 20060101

TNF-alpha production-enhancing activity of 2-(1-adamantylamino)-6-methylpyridine (AdAMP) in cultures of human normal and neoplastic cells.

Anticancer research 20060101

Therapeutic options in development for management of diabetes: pharmacologic agents and new technologies.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20060101

[RF9, a powerful and selective antagonist of the neuropeptide FF receptors, prevents the development of the tolerance to opioids].

Medecine sciences : M/S 20060101

[Comparative study of the effect of Ladasten, Sydnocarb and their combination on physical work ability of laboratory animals].

Eksperimental'naia i klinicheskaia farmakologiia 20060101

Pharmacological Profile of U-37883A, a Channel Blocker of Smooth Muscle-Type ATP-Sensitive K Channels.

Cardiovascular drug reviews 20060101

[Pilot clinical trial of ladasten].

Eksperimental'naia i klinicheskaia farmakologiia 20060101

[An old pathway to new antibiotics--platensimycin].

Pharmazie in unserer Zeit 20060101

Soluble adamantyl glycosphingolipid analogs as probes of glycosphingolipid function.

Methods in molecular biology (Clifton, N.J.) 20060101

Novel method to identify illegal diesel fuel, I: use of adamantane or [1, 2-D2] n-tetradecane as chemical marker.

Environmental sciences : an international journal of environmental physiology and toxicology 20060101

Vildagliptin.

Drugs 20060101

Rapid and highly informative diagnostic assay for H5N1 influenza viruses.

PloS one 20060101

Synthesis and antibacterial activity of 5-adamantan-1-yl-methyl analogues of trimethoprim.

Acta poloniae pharmaceutica 20060101

[Therapeutic efficacy of 4-(adamantyl-1)-1-(1-aminobutyl) benzene in experimental fungal pathology].

Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20060101

New bradykinin analogues modified in the C-terminal part with sterically restricted 1-aminocyclohexane-1-carboxylic acid.

Journal of medicinal chemistry 20051215

Evidence for different types of water participation in the solvolysis of 1-adamantyl, tert-butyl, and methyl chlorides from density functional theory computations.

The Journal of organic chemistry 20051209

Skeleton-selective fluorescent chemosensor based on cyclodextrin bearing a 4-amino-7-nitrobenz-2-oxa-1,3-diazole moiety.

Organic & biomolecular chemistry 20051207

BP-1107 [{2-[4-(2,4-dioxo-thiazolidin-5-ylmethyl)-phenoxy]-ethyl}-methyl-amide]: a novel synthetic thiazolidinedione that inhibits epidermal hyperplasia in psoriatic skin-severe-combined immunodeficient mouse transplants after topical application.

The Journal of pharmacology and experimental therapeutics 20051201

An epoxide hydrolase inhibitor, 12-(3-adamantan-1-yl-ureido)dodecanoic acid (AUDA), reduces ischemic cerebral infarct size in stroke-prone spontaneously hypertensive rats.

Journal of cardiovascular pharmacology 20051201

Small molecules thwart crash and burn.

Nature chemical biology 20051201

Small molecules that delay S phase suppress a zebrafish bmyb mutant.

Nature chemical biology 20051201

A study of free radical release from beta-cyclodextrin-anticancer pro-drugs adducts in water.

Journal of controlled release : official journal of the Controlled Release Society 20051128

Surface plasmon resonance study of the interaction of a beta-cyclodextrin polymer and hydrophobically modified poly(N-isopropylacrylamide).

Langmuir : the ACS journal of surfaces and colloids 20051122

The cucurbit[n]uril family: prime components for self-sorting systems.

Journal of the American Chemical Society 20051116

Multiple actions of U-37883A, an ATP-sensitive K+ channel blocker, on membrane currents in pig urethra.

European journal of pharmacology 20051107

Acute and chronic effects of the incretin enhancer vildagliptin in insulin-resistant rats.

The Journal of pharmacology and experimental therapeutics 20051101

Pharmacoproteomic effects of isoniazid, ethambutol, and N-geranyl-N'-(2-adamantyl)ethane-1,2-diamine (SQ109) on Mycobacterium tuberculosis H37Rv.

The Journal of pharmacology and experimental therapeutics 20051101

Improved glycaemic control with dipeptidyl peptidase-4 inhibition in patients with type 2 diabetes: vildagliptin (LAF237) dose response.

Diabetes, obesity & metabolism 20051101

Effective inhibition of experimental metastasis and prolongation of survival in mice by a potent factor Xa-specific synthetic serine protease inhibitor with weak anticoagulant activity.

Thrombosis and haemostasis 20051101

[Effects of blockade of ionotropic glutamate receptors on the development of pentylenetetrazole kindling in mice].

Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20051101

The role of Mcl-1 downregulation in the proapoptotic activity of the multikinase inhibitor BAY 43-9006.

Oncogene 20051020

Design, synthesis, and structure-activity relationship of podocarpic acid amides as liver X receptor agonists for potential treatment of atherosclerosis.

Bioorganic & medicinal chemistry letters 20051015

Temperature-dependent and friction-controlled electrochemically induced shuttling along molecular strings associated with electrodes.

Chemphyschem : a European journal of chemical physics and physical chemistry 20051014

One-pot synthesis of adamantane derivatives by domino Michael reactions from ethyl 2,4-dioxocyclohexanecarboxylate.

The Journal of organic chemistry 20051014

Beta-cell expression of a dominant-negative HNF-1alpha compromises the ability of inhibition of dipeptidyl peptidase-4 to elicit a long-term augmentation of insulin secretion in mice.

European journal of pharmacology 20051003

Rendering of quantum topological atoms and bonds.

Journal of molecular graphics & modelling 20051001

Adamantyl triazoles as selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1.

Bioorganic & medicinal chemistry letters 20051001

Effect of cyclic third components on non-deoxygenated RTP and their potential in developing optical thermometer.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20051001

An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-sensitive hypertension.

Hypertension (Dallas, Tex. : 1979) 20051001

Resistance to anti-influenza agents.

Lancet (London, England) 20051001

Incidence of adamantane resistance among influenza A (H3N2) viruses isolated worldwide from 1994 to 2005: a cause for concern.

Lancet (London, England) 20051001

Incretins: what does the future hold?

Diabetes technology & therapeutics 20051001

Evolution of H5N1 avian influenza viruses in Asia.

Emerging infectious diseases 20051001

Towards nanomedicine with a supramolecular approach: a review.

IEE proceedings. Nanobiotechnology 20051001

Neuraminidase inhibitors for influenza.

The New England journal of medicine 20050929

Boc-protected amines via a mild and efficient one-pot Curtius rearrangement.

Organic letters 20050915

High-pressure study of adamantane: variable shape simulations up to 26 GPa.

The journal of physical chemistry. B 20050915

NCN pincer palladium complexes: their preparation via a ligand introduction route and their catalytic properties.

Journal of the American Chemical Society 20050907

Incretin mimetics: promising new therapeutic options in the treatment of type 2 diabetes.

Journal of managed care pharmacy : JMCP 20050901

Transcriptional profiling identifies altered intracellular labile iron homeostasis as a contributing factor to the toxicity of adaphostin: decreased vascular endothelial growth factor secretion is independent of hypoxia-inducible factor-1 regulation.

Clinical cancer research : an official journal of the American Association for Cancer Research 20050901

The novel cannabinoid agonist AM 411 produces a biphasic effect on accuracy in a visual target detection task in rats.

Behavioural pharmacology 20050901

[Small molecules that control gene expression].

Seikagaku. The Journal of Japanese Biochemical Society 20050901

Microcalorimetric study on micellization of nonionic surfactants with a benzene ring or adamantane in their hydrophobic chains.

The journal of physical chemistry. B 20050825

Vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed beta-cell function in patients with type 2 diabetes.

The Journal of clinical endocrinology and metabolism 20050801

Artificial transcriptional activation domains.

Chembiochem : a European journal of chemical biology 20050801

Design of antagonists for NMDA and AMPA receptors.

Neuropharmacology 20050801

Peak shape modeling by Haarhoff-Van der Linde function for the determination of correct migration times: a new insight into affinity capillary electrophoresis.

Electrophoresis 20050801

Improved meal-related beta-cell function and insulin sensitivity by the dipeptidyl peptidase-IV inhibitor vildagliptin in metformin-treated patients with type 2 diabetes over 1 year.

Diabetes care 20050801

American Diabetes Association - 65th Scientific Sessions. DDP-IV inhibitors.

IDrugs : the investigational drugs journal 20050801

Synthesis and structure-activity relationships of a new series of retinoid-related biphenyl-4-ylacrylic acids endowed with antiproliferative and proapoptotic activity.

Journal of medicinal chemistry 20050728

Spiro and dispiro-1,2,4-trioxolanes as antimalarial peroxides: charting a workable structure-activity relationship using simple prototypes.

Journal of medicinal chemistry 20050728

Discovery and preclinical profile of Saxagliptin (BMS-477118): a highly potent, long-acting, orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.

Journal of medicinal chemistry 20050728

Structural investigations of pyridin-4-yl indolizine modified beta-cyclodextrin derivatives as fluorescent chemosensors for organic guest molecules.

Carbohydrate research 20050725

Adamantyl cannabinoids: a novel class of cannabinergic ligands.

Journal of medicinal chemistry 20050714

Tuning tetranuclear manganese-oxo core electronic properties: adamantane-shaped complexes synthesized by ligand exchange.

Inorganic chemistry 20050711

Two mechanisms of action of the adamantane derivative IEM-1460 at human AMPA-type glutamate receptors.

British journal of pharmacology 20050701

Inhibition of dipeptidyl-peptidase IV catalyzed peptide truncation by Vildagliptin ((2S)-{[(3-hydroxyadamantan-1-yl)amino]acetyl}-pyrrolidine-2-carbonitrile).

Biochemical pharmacology 20050701

Development of resistance to the atypical retinoid, ST1926, in the lung carcinoma cell line H460 is associated with reduced formation of DNA strand breaks and a defective DNA damage response.

Neoplasia (New York, N.Y.) 20050701

Kinetic acidity of aliphatic hydrocarbons. Hydrogen isotope exchange with cesium cyclohexylamide in cyclohexylamine.

Journal of the American Chemical Society 20050629

Dispiro-1,2,4-trioxane analogues of a prototype dispiro-1,2,4-trioxolane: mechanistic comparators for artemisinin in the context of reaction pathways with iron(II).

The Journal of organic chemistry 20050624

Potent estrogen receptor ligands based on bisphenols with a globular hydrophobic core.

Journal of medicinal chemistry 20050616

In vitro and in vivo evaluation of ruthenium(II)-arene PTA complexes.

Journal of medicinal chemistry 20050616

Adamantoylated monosaccharides: new compounds for modification of the properties of cyclodextrin-containing materials.

Carbohydrate research 20050613

1H NMR studies on the hydrogen-bonding network in mono-altro-beta-cyclodextrin and its complex with adamantane-1-carboxylic acid.

Carbohydrate research 20050613

Is it true dioxygenase or classic autoxidation catalysis? Re-investigation of a claimed dioxygenase catalyst based on a Ru(2)-incorporated, polyoxometalate precatalyst.

Inorganic chemistry 20050613

Apoptosis induction by a novel retinoid-related molecule requires nuclear factor-kappaB activation.

Cancer research 20050601

Neurobiology of executive functions: catecholamine influences on prefrontal cortical functions.

Biological psychiatry 20050601

Optimization of amide-based inhibitors of soluble epoxide hydrolase with improved water solubility.

Journal of medicinal chemistry 20050519

Complexation of adamantyl compounds by beta-cyclodextrin and monoaminoderivatives.

The journal of physical chemistry. B 20050519

Interaction of acetylcholine with Kir6.1 channels heterologously expressed in human embryonic kidney cells.

European journal of pharmacology 20050516

2:2 Fe(III):ligand and 'adamantane core' 4:2 Fe(III):ligand (hydr)oxo complexes of an acyclic ditopic ligand.

Dalton transactions (Cambridge, England : 2003) 20050505

Endogenous neurotensin in the ventral tegmental area contributes to amphetamine behavioral sensitization.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050501

Role of nonfeminizing estrogen analogues in neuroprotection of rat retinal ganglion cells against glutamate-induced cytotoxicity.

Free radical biology & medicine 20050501

Raman study of structural relaxation and boson peak in amorphous films of adamantane.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050501

Treatments and devices for future diabetes management.

Nursing times 20050501

Behavioral effects of the novel cannabinoid full agonist AM 411.

Pharmacology, biochemistry, and behavior 20050501

Short-term effects of endocrine-disrupting chemicals on the expression of estrogen-responsive genes in male medaka (Oryzias latipes).

Aquatic toxicology (Amsterdam, Netherlands) 20050430

The novel GABA adamantane derivative (AdGABA): design, synthesis, and activity relationship with gabapentin.

Bioorganic & medicinal chemistry 20050415

Luminescent ruthenium(II)- and rhenium(I)-diimine wires bind nitric oxide synthase.

Journal of the American Chemical Society 20050413

Multivalent host-guest interactions between beta-cyclodextrin self-assembled monolayers and poly(isobutene-alt-maleic acid)s modified with hydrophobic guest moieties.

Chemistry (Weinheim an der Bergstrasse, Germany) 20050408

Soluble epoxide hydrolase is a main effector of angiotensin II-induced hypertension.

Hypertension (Dallas, Tex. : 1979) 20050401

Synthesis and water solubility of adamantyl-OEG-fullerene hybrids.

The Journal of organic chemistry 20050401

The molecular basis of memantine action in Alzheimer's disease and other neurologic disorders: low-affinity, uncompetitive antagonism.

Current Alzheimer research 20050401

Triflic acid-catalyzed adamantylation of aromatics in [BMIM][OTf] ionic liquid; synthetic scope and mechanistic insight.

Organic & biomolecular chemistry 20050321

Evidence of a self-inclusion phenomenon for a new class of mono-substituted alkylammonium-beta-cyclodextrins.

Organic & biomolecular chemistry 20050321

Modulation of survival signaling pathways and persistence of the genotoxic stress as a basis for the synergistic interaction between the atypical retinoid ST1926 and the epidermal growth factor receptor inhibitor ZD1839.

Cancer research 20050315

Adaphostin-induced apoptosis in CLL B cells is associated with induction of oxidative stress and exhibits synergy with fludarabine.

Blood 20050301

The adamantane-derived bananins are potent inhibitors of the helicase activities and replication of SARS coronavirus.

Chemistry & biology 20050301

Psychotropic effects of sidnocarb and ladasten in inbred mice with different reaction to emotional stress.

Bulletin of experimental biology and medicine 20050301

Perfluoroadamantane and its negative ion.

The journal of physical chemistry. A 20050224

Solutes probe hydration in specific association of cyclodextrin and adamantane.

Journal of the American Chemical Society 20050223

Synthesis, X-ray crystal structure study, and cytostatic and antiviral evaluation of the novel cycloalkyl-N-aryl-hydroxamic acids.

Journal of medicinal chemistry 20050210

Pressure-induced ordering in adamantane: a Monte Carlo simulation study.

The journal of physical chemistry. B 20050210

Substrate modulation of the properties and reactivity of the oxy-ferrous and hydroperoxo-ferric intermediates of cytochrome P450cam as shown by cryoreduction-EPR/ENDOR spectroscopy.

Journal of the American Chemical Society 20050209

Analytical time-dependent density functional derivative methods within the RI-J approximation, an approach to excited states of large molecules.

The Journal of chemical physics 20050208

Vibrational spectra and chemical quantum calculations for 2-adamantylamino-5-nitropyridine crystals--a novel material for laser Raman converters.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050201

Novel spiroanellated 1,2,4-trioxanes with high in vitro antimalarial activities.

Bioorganic & medicinal chemistry letters 20050201

Structural requirements for inhibitors of cytochromes P450 2B: assessment of the enzyme interaction with diamondoids.

Journal of enzyme inhibition and medicinal chemistry 20050201

Molecular printboards on silicon oxide: lithographic patterning of cyclodextrin monolayers with multivalent, fluorescent guest molecules.

Small (Weinheim an der Bergstrasse, Germany) 20050201

Effects of 1, 6-Bis[4-(4-amino-3-hydroxyphenoxy)phenyl]diamantane (DPD), a reactive oxygen species and apoptosis inducing agent, on human leukemia cells in vitro and in vivo.

Toxicology and applied pharmacology 20050101

Antitumor effect of valorphin in vitro and in vivo: combined action with cytostatic drugs.

Cancer biology & therapy 20050101

[Antiviral action of membranotropic compounds modified by adamantane and norbornene pharmacophores exerted on different HIV-1 strains].

Molekuliarnaia genetika, mikrobiologiia i virusologiia 20050101

The effect of ladasten on gene expression in the rat brain.

Doklady. Biochemistry and biophysics 20050101

[Studying the mechanisms of ladasten action].

Eksperimental'naia i klinicheskaia farmakologiia 20050101

[Effect of ladasten on reproduction function in male rats].

Eksperimental'naia i klinicheskaia farmakologiia 20050101

The GLP-1 system as a therapeutic target.

Annals of medicine 20050101

Electronic effects steer the mechanism of asymmetric hydrogenations of unfunctionalized aryl-substituted alkenes.

Journal of the American Chemical Society 20041229

Small molecule transcription factor mimic.

Journal of the American Chemical Society 20041215

Effects of U-37883A on intracellular Ca2+ -activated large-conductance K+ channels in pig proximal urethral myocytes.

European journal of pharmacology 20041203

Neurotensin receptor antagonist SR 142948A alters Fos expression and extrapyramidal side effect profile of typical and atypical antipsychotic drugs.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20041201

Cross polarization, radio frequency field homogeneity, and circuit balancing in high field solid state NMR probes.

Journal of magnetic resonance (San Diego, Calif. : 1997) 20041201

Twelve- and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 in metformin-treated patients with type 2 diabetes.

Diabetes care 20041201

Electromechanics of a redox-active rotaxane in a monolayer assembly on an electrode.

Journal of the American Chemical Society 20041201

Novel adamantylated pyrimidines and their preliminary biological evaluations.

Farmaco (Societa chimica italiana : 1989) 20041201

Paradigm shift in NMDA receptor antagonist drug development: molecular mechanism of uncompetitive inhibition by memantine in the treatment of Alzheimer's disease and other neurologic disorders.

Journal of Alzheimer's disease : JAD 20041201

Synthesis of rigid multivalent scaffolds based on adamantane.

Organic letters 20041125

Polymer bilayer formation due to specific interactions between beta-cyclodextrin and adamantane: a surface force study.

Langmuir : the ACS journal of surfaces and colloids 20041123

Conformational states of cytochrome P450cam revealed by trapping of synthetic molecular wires.

Journal of molecular biology 20041119

Digital photoswitching of fluorescence based on the photochromism of diarylethene derivatives at a single-molecule level.

Journal of the American Chemical Society 20041117

Azaadamantane benzamide 5-HT4 agonists: gastrointestinal prokinetic SC-54750.

Bioorganic & medicinal chemistry letters 20041115

Synthesis of 61-bis(1-adamantylcarbamoyl)-1,2-methano[60]fullerene and its antagonistic effect on haloperidol-induced catalepsy in mice.

Bioorganic & medicinal chemistry letters 20041115

Oxazatricyclic noradamantanes: stereocontrolled synthesis of functionalized scopolines, related cage molecules, and drug leads.

Organic letters 20041111

Efficient synthesis of 1-adamantanecarboxaldehyde by the GaCl3-mediated carbonylation of adamantane under mild reaction conditions.

Organic letters 20041111

Non-empirical calculations of NMR indirect carbon-carbon coupling constants. Part 10--carbocages.

Magnetic resonance in chemistry : MRC 20041101

(-)-Adamantyl-delta8-tetrahydrocannabinol (AM-411), a selective cannabinoid CB1 receptor agonist: effects on open-field behaviors and antagonism by SR-141716 in rats.

Behavioural pharmacology 20041101

Activation of A3 adenosine receptors attenuates lung injury after in vivo reperfusion.

Anesthesiology 20041101

Molecular crystal global phase diagrams. I. Method of construction.

Acta crystallographica. Section A, Foundations of crystallography 20041101

Sigma receptor ligands: applications in inflammation and oncology.

Current opinion in investigational drugs (London, England : 2000) 20041101

Cellular and pharmacological bases of the antitumor activity of a novel adamantyl retinoid, ST1926.

Journal of chemotherapy (Florence, Italy) 20041101

Synthesis and biological evaluation of novel N6-[4-(substituted)sulfonamidophenylcarbamoyl]adenosine-5'-uronamides as A3 adenosine receptor agonists.

Journal of medicinal chemistry 20041021

Solvent-equilibrated ion pairs from carbene fragmentation reactions.

Journal of the American Chemical Society 20041006

Negative feedback regulation of nigrostriatal dopamine release: mediation by striatal D1 receptors.

The Journal of pharmacology and experimental therapeutics 20041001

LAF-237 (Novartis).

Current opinion in investigational drugs (London, England : 2000) 20041001

Adamantylsulfanyl- and N-adamantylcarboxamido-derivatives of heterocycles and phenols: synthesis, crystal structure, tumor necrosis factor-alpha production-enhancing properties, and theoretical considerations.

Chemistry & biodiversity 20041001

The hydrophilic phosphatriazaadamantane ligand in the development of H2 production electrocatalysts: iron hydrogenase model complexes.

Journal of the American Chemical Society 20040929

Topological analysis of electron densities: is the presence of an atomic interaction line in an equilibrium geometry a sufficient condition for the existence of a chemical bond?

Chemistry (Weinheim an der Bergstrasse, Germany) 20040920

A homoleptic molybdenum(IV) enolate complex: synthesis, molecular and electronic structure, and NCN group transfer to form a terminal cyanoimide of molybdenum(VI).

Journal of the American Chemical Society 20040915

[A novel microbeads-based chemiluminescence immunoassay for detecting human thyrotropin].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20040901

6-[2-(adamantylidene)-hydroxybenzoxazole]-O-sulfamate, a steroid sulfatase inhibitor for the treatment of androgen- and estrogen-dependent diseases.

The Journal of steroid biochemistry and molecular biology 20040901

Immobilization of a (dextran-adamantane-COOH) polymer onto beta-cyclodextrin-modified silica.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040825

2-(1-adamantyl)-4-(thio)chromenone-6-carboxylic acids: potent reversible inhibitors of human steroid sulfatase.

Journal of medicinal chemistry 20040812

Membrane permeability related physicochemical properties of a novel gamma-secretase inhibitor.

International journal of pharmaceutics 20040806

Alkane oxidation via photochemical excitation of a self-assembled molecular cage.

Journal of the American Chemical Society 20040804

Gas hydrate single-crystal structure analyses.

Journal of the American Chemical Society 20040804

In vitro and in vivo growth inhibition and G1 arrest in human cancer cell lines by diaminophenyladamantane derivatives.

Anti-cancer drugs 20040801

Targeted delivery of RNA-cleaving DNA enzyme (DNAzyme) to tumor tissue by transferrin-modified, cyclodextrin-based particles.

Cancer biology & therapy 20040701

Blockade of neurotensin receptors affects differently hypo-locomotion and catalepsy induced by haloperidol in mice.

Neuropharmacology 20040701

Inhibition of glycolipid biosynthesis by N-(5-adamantane-1-yl-methoxy-pentyl)-deoxynojirimycin protects against the inflammatory response in hapten-induced colitis.

International immunopharmacology 20040701

Antagonist analogue of 6-[3'-(1-adamantyl)-4'-hydroxyphenyl]-2-naphthalenecarboxylic acid (AHPN) family of apoptosis inducers that effectively blocks AHPN-induced apoptosis but not cell-cycle arrest.

Journal of medicinal chemistry 20040701

Development of potent bifunctional endomorphin-2 analogues with mixed mu-/delta-opioid agonist and delta-opioid antagonist properties.

Journal of medicinal chemistry 20040701

Vibrational frequencies and structural determination of adamantane.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040701

Organic nitriles from acid chlorides: an isovalent N for (O)CL exchange reaction mediated by a tungsten nitride complex.

Journal of the American Chemical Society 20040630

Molecular printboards: monolayers of beta-cyclodextrins on silicon oxide surfaces.

Langmuir : the ACS journal of surfaces and colloids 20040622

Photochemical patterning of a self-assembled monolayer of 7-diazomethylcarbonyl-2,4,9-trithiaadmantane on gold films via Wolff rearrangement.

Langmuir : the ACS journal of surfaces and colloids 20040608

Photochemical preparation of 1,3,5,7-tetracyanoadamantane and its conversion to 1,3,5,7-tetrakis(aminomethyl)adamantane.

Organic letters 20040527

Carbonic anhydrase inhibitors: aromatic and heterocyclic sulfonamides incorporating adamantyl moieties with strong anticonvulsant activity.

Bioorganic & medicinal chemistry 20040515

Inhibition of dipeptidyl peptidase-4 reduces glycemia, sustains insulin levels, and reduces glucagon levels in type 2 diabetes.

The Journal of clinical endocrinology and metabolism 20040501

Computational study of the conformational preferences of the (R)-8-amino-pentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecane-8-carboxylic acid monopeptide.

Journal of peptide science : an official publication of the European Peptide Society 20040501

Combination of paclitaxel and nitric oxide as a novel treatment for the reduction of restenosis.

Journal of medicinal chemistry 20040422

[Me2NN]Co(eta6-toluene): O=O, N=N, and O=N bond cleavage provides beta-diketiminato cobalt mu-oxo and imido complexes.

Journal of the American Chemical Society 20040421

Crystal structure of the supramolecular linear polymer formed by the self-assembly of mono-6-deoxy-6-adamantylamide-beta-cyclodextrin.

Acta crystallographica. Section B, Structural science 20040401

A wrench-shaped synthetic molecule that modulates a transcription factor-coactivator interaction.

Journal of the American Chemical Society 20040324

Experimental and theoretical investigations of structural trends for selenium(IV) imides and oxides: X-ray structure of Se3(NAd)2.

Inorganic chemistry 20040322

Gramicidin-based channel systems for the detection of protein-ligand interaction.

Bioorganic & medicinal chemistry 20040315

Apoptosis signaling by the novel compound 3-Cl-AHPC involves increased EGFR proteolysis and accompanying decreased phosphatidylinositol 3-kinase and AKT kinase activities.

Oncogene 20040311

Accurate determinations of the extent to which the SE2' reactions of allyl-, allenyl- and propargylsilanes are stereospecifically anti.

Organic & biomolecular chemistry 20040307

Induction of apoptosis and stress response in ovarian carcinoma cell lines treated with ST1926, an atypical retinoid.

Cell death and differentiation 20040301

Molecular analysis of the subtype-selective inhibition of cloned KATP channels by PNU-37883A.

British journal of pharmacology 20040301

High-resolution NMR imaging of objects with dipolar-broadened spectra.

Journal of magnetic resonance (San Diego, Calif. : 1997) 20040301

Bowdichine, a new diaza-adamantane alkaloid from Bowdichia virgilioides.

Journal of Asian natural products research 20040301

Pruritus-associated response mediated by cutaneous histamine H3 receptors.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040301

Induction of growth inhibition and G1 arrest in human cancer cell lines by relatively low-toxic diamantane derivatives.

Anti-cancer drugs 20040301

Synthesis of well-defined tower-shaped 1,3,5-trisubstituted adamantanes incorporating a macrocyclic trilactam ring system.

The Journal of organic chemistry 20040220

Induction of apoptosis in human leukemia cells by the tyrosine kinase inhibitor adaphostin proceeds through a RAF-1/MEK/ERK- and AKT-dependent process.

Oncogene 20040219

Comparison of the anticonvulsive activities of organic mono- and dications with their abilities to inhibit NMDA and AMPA glutamate receptors.

Neuroscience and behavioral physiology 20040201

ST1926, a novel and orally active retinoid-related molecule inducing apoptosis in myeloid leukemia cells: modulation of intracellular calcium homeostasis.

Blood 20040101

Preparation of visible light active S-doped TiO2 photocatalysts and their photocatalytic activities.

Water science and technology : a journal of the International Association on Water Pollution Research 20040101

[Estimation of the protective effect of the novel potential antiparkinsonian agent himantane against MPTP neurotoxicity].

Eksperimental'naia i klinicheskaia farmakologiia 20040101

Medium effect on the enzymatically triggered electron-exchange luminescence of the biologically important dioxetane.

Doklady. Biochemistry and biophysics 20040101

Neurotensin depolarizes globus pallidus neurons in rats via neurotensin type-1 receptor.

Neuroscience 20040101

[Effect of ladasten on the proteinase C activity in the rat brain cells].

Eksperimental'naia i klinicheskaia farmakologiia 20040101

[Comparative study of neurophysiological effects of adamantane derivatives in the experimental parkinsonism model].

Eksperimental'naia i klinicheskaia farmakologiia 20040101

[The effect of ladasten on the activity of cAMP-dependent protein kinases and the phosphorylation of proteins in brain cells of rats].

Eksperimental'naia i klinicheskaia farmakologiia 20040101

A new class of arylpiperazine derivatives: the library synthesis on SynPhase lanterns and biological evaluation on serotonin 5-HT(1A) and 5-HT(2A) receptors.

Journal of combinatorial chemistry 20040101

[Clinico-neurophysiologic and experimental study of the peculiarities of adamantan-sulphate treatment in Parkinson's disease].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20040101

[Ladasten induces the expression of genes regulating dopamine biosynthesis in various structures of rat brain].

Eksperimental'naia i klinicheskaia farmakologiia 20040101

Synthetic biocompatible cyclodextrin-based constructs for local gene delivery to improve cutaneous wound healing.

Bioconjugate chemistry 20040101

[The effect of ladasten on the activation-induced expression of Fas receptor on T-lymphocytes and their sensitivity to Fas-induced apoptosis].

Eksperimental'naia i klinicheskaia farmakologiia 20040101

Agonists and antagonists acting at P2X7 receptor.

Current topics in medicinal chemistry 20040101

[The effect of long-term administration of isatin and himantan to mice on sensitivity of brain monoamine oxidase B to inhibition by deprenyl in vivo and in vitro].

Biomeditsinskaia khimiia 20040101

[The effect of hemantane on the generative function and gonad morphology in rats].

Eksperimental'naia i klinicheskaia farmakologiia 20040101

Failures and successes of NMDA receptor antagonists: molecular basis for the use of open-channel blockers like memantine in the treatment of acute and chronic neurologic insults.

NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics 20040101

Synthesis and antibacterial activity of adamantyl substituted pyrimidines.

Acta poloniae pharmaceutica 20040101

Molecular structure of crude beeswax studied by solid-state 13C NMR.

Journal of insect science (Online) 20040101

Electrochemical gene detection by using adamantyl naphthalene diimide coupled with ferrocenyl-beta-cyclodextrin.

Nucleic acids symposium series (2004) 20040101

Involvement of reactive oxygen species in adaphostin-induced cytotoxicity in human leukemia cells.

Blood 20031215

First direct evidence for stereospecific olefin epoxidation and alkane hydroxylation by an oxoiron(IV) porphyrin complex.

Journal of the American Chemical Society 20031203

Hit-to-Lead studies: the discovery of potent adamantane amide P2X7 receptor antagonists.

Bioorganic & medicinal chemistry letters 20031117

Study of in vitro and in vivo effects of 1,6-Bis[4-(4-amino-3-hydroxyphenoxy)phenyl]diamantane (DPD), a novel cytostatic and differentiation inducing agent, on human colon cancer cells.

British journal of cancer 20031117

Induction of apoptosis in retinoid-refractory acute myelogenous leukemia by a novel AHPN analog.

Blood 20031115

Computer-aided design of a factor Xa inhibitor by using MCSS functionality maps and a CAVEAT linker search.

Journal of molecular graphics & modelling 20031101

An application of the XiX decoupling for solid state 13C NMR with mobile samples.

Journal of magnetic resonance (San Diego, Calif. : 1997) 20031101

Entrapment of peptidoglycans and adamantyltripeptides into liposomes: an HPLC assay for determination of encapsulation efficiency.

Journal of liposome research 20031101

Conformational studies by dynamic NMR. 95. Rotation around the adamantyl-alkyl bond. Remote substituent effect on conformational equilibrium.

The Journal of organic chemistry 20031031

Highly emissive supramolecular oligo(p-phenylene vinylene) dendrimers.

Journal of the American Chemical Society 20031022

A system of protein target sequences for anti-RNA-viral chemotherapy by a vitamin B6-derived zinc-chelating trioxa-adamantane-triol.

Bioorganic & medicinal chemistry 20031015

Nanosecond photoreduction of cytochrome p450cam by channel-specific Ru-diimine electron tunneling wires.

Journal of the American Chemical Society 20031015

Determination of drug synergism between the tyrosine kinase inhibitors NSC 680410 (adaphostin) and/or STI571 (imatinib mesylate, Gleevec) with cytotoxic drugs against human leukemia cell lines.

Cancer chemotherapy and pharmacology 20031001

Radioprotective and antitumor activity evaluation of newly synthesized adamantyl tenocyclidines.

Cancer biotherapy & radiopharmaceuticals 20031001

Modified field amplification sample injection for micellar electrokinetic chromatography of neutral compounds with amino-substituted cyclodextrin as carrier and 1-adamantanecarboxylate as displacer.

Journal of chromatography. A 20030926

On the viability of small endohedral hydrocarbon cage complexes: X@C4H4, X@C8H8, X@C8H14, X@C10H16, X@C12H12, AND X@C16H16.

Journal of the American Chemical Society 20030917

Molybdenum-phosphorus triple bond stabilization by ancillary alkoxide ligation: synthesis and structure of a terminal phosphide tris-1-methylcyclohexanoxide complex.

Journal of the American Chemical Society 20030806

Synthesis and antioxidant activity evaluation of novel antiparkinsonian agents, aminoadamantane derivatives of nitroxyl free radical.

Bioorganic & medicinal chemistry 20030805

Gas chromatography study of silica modified with polyfluoroalkyl groups.

Journal of chromatography. A 20030801

Theoretical analysis of a carbon-carbon dimer placement tool for diamond mechanosynthesis.

Journal of nanoscience and nanotechnology 20030801

Influence of cyclodextrin molecules on the synthesis and the thermoresponsive solution behavior of N-isopropylacrylamide copolymers with adamantyl groups in the side-chains.

Angewandte Chemie (International ed. in English) 20030714

Synthesis of 1-boraadamantaneamine derivatives with selective astrocyte vs C6 glioma antiproliferative activity. A novel class of anti-hepatitis C agents with potential to bind CD81.

Journal of medicinal chemistry 20030703

Noncompetitive antagonist binding sites in the torpedo nicotinic acetylcholine receptor ion channel. Structure-activity relationship studies using adamantane derivatives.

Biochemistry 20030624

1-[[(3-hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: a potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties.

Journal of medicinal chemistry 20030619

Nanoscale tripodal 1,3,5,7-tetrasubstituted adamantanes for AFM applications.

The Journal of organic chemistry 20030613

Chemical shift referencing in MAS solid state NMR.

Journal of magnetic resonance (San Diego, Calif. : 1997) 20030601

1-Azaadamantanes: pharmacological applications and synthetic approaches.

Current medicinal chemistry. Cardiovascular and hematological agents 20030601

Spiro[pyrrolidine-2,2'-adamantanes]: synthesis, anti-influenza virus activity and conformational properties.

Bioorganic & medicinal chemistry letters 20030519

Influence of carbocation stability in the gas phase on solvolytic reactivity: beyond bridgehead derivatives.

The Journal of organic chemistry 20030516

A theoretical study of reactivity and regioselectivity in the hydroxylation of adamantane by ferrate(VI).

The Journal of organic chemistry 20030516

Adamantane-like cluster complexes of mixed-valent copper-copper and nickel-copper thiolates.

Inorganic chemistry 20030505

[3H]R214127: a novel high-affinity radioligand for the mGlu1 receptor reveals a common binding site shared by multiple allosteric antagonists.

Molecular pharmacology 20030501

A gene-expression inhibitor that targets an alpha-helix-mediated protein interaction.

Journal of the American Chemical Society 20030430

Modular amino alcohol ligands containing bulky alkyl groups as chiral controllers for Et2Zn addition to aldehydes: illustration of a design principle.

The Journal of organic chemistry 20030418

A spin labelling study of immunomodulating peptidoglycan monomer and adamantyltripeptides entrapped into liposomes.

Biochimica et biophysica acta 20030401

Possible role for memantine in protecting retinal ganglion cells from glaucomatous damage.

Survey of ophthalmology 20030401

Fluorescent quenching of the 2-naphthoxide anion by aliphatic and aromatic halides. Mechanism and consequences of electron transfer reactions.

The Journal of organic chemistry 20030321

Establishment of steric substituent constants in the adamantane system by ab initio calculations.

Organic letters 20030320

Twisted amide reduction under Wolff-Kishner conditions: synthesis of a benzo-1-aza-adamantane derivative.

Journal of the American Chemical Society 20030319

A novel atypical retinoid endowed with proapoptotic and antitumor activity.

Journal of medicinal chemistry 20030313

Reactivities of organic phase biosensors: 6. Square-wave and differential pulse studies of genetically engineered cytochrome P450(cam) (CYP101) bioelectrodes in selected solvents.

Biosensors & bioelectronics 20030301

Studies of the structure of glutamate receptor ion channels and the mechanisms of their blockade by organic cations.

Neuroscience and behavioral physiology 20030301

[Role of NMDA and AMPA glutamate receptors in the mechanism of korazol-induced convulsions in mice].

Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20030301

3'Sulfogalactolipid binding specifically inhibits Hsp70 ATPase activity in vitro.

Biochemistry 20030218

[Treatment of influenza in children].

Zhonghua er ke za zhi = Chinese journal of pediatrics 20030201

Effects of cholecystokinin tetrapeptide (CCK(4)) and of anxiolytic drugs on GABA outflow from the cerebral cortex of freely moving rats.

Neurochemistry international 20030101

Microwave-assisted synthesis of O'-adamantylated uracil-derived nucleosides.

Nucleosides, nucleotides & nucleic acids 20030101

[Evaluation of the prolonged immunotropic effect of the potential antiparkinson agent himantane].

Eksperimental'naia i klinicheskaia farmakologiia 20030101

[Comparative study of the distribution of 3[H]-himantane in the brain structures and the thymus of rats].

Eksperimental'naia i klinicheskaia farmakologiia 20030101

[HIV-inhibiting activity of polyanion matrices and related substances containing adamantane and norbornene pharmacophores].

Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101

An adamantanone derivative that is an original modulator of redox processes in the cytochrome P-450 system can serve as an effective remedy against obliterating angiopathy of lower extremities.

Doklady. Biochemistry and biophysics 20030101

[Structure and antiviral activity of adamantane-containing polymer preparation].

Voprosy virusologii 20030101

Transferrin-containing, cyclodextrin polymer-based particles for tumor-targeted gene delivery.

Bioconjugate chemistry 20030101

[Effect of a new antiparkinsonian drug himantane on monoamine oxidase activity].

Eksperimental'naia i klinicheskaia farmakologiia 20030101

[Effect of himantane on the rat embryo development].

Eksperimental'naia i klinicheskaia farmakologiia 20030101

New flexible synthesis of pyrazoles with different, functionalized substituents at C3 and C5.

The Journal of organic chemistry 20021227

Interaction of the verotoxin 1B subunit with soluble aminodeoxy analogues of globotriaosyl ceramides.

The Biochemical journal 20021215

Role of protein and substrate dynamics in catalysis by Pseudomonas putida cytochrome P450cam.

Biochemistry 20021210

SSR125329A, a high affinity sigma receptor ligand with potent anti-inflammatory properties.

European journal of pharmacology 20021205

Crystal structures of dipeptides containing the Dmt-Tic pharmacophore.

Journal of medicinal chemistry 20021205

In vitro and in vivo evaluations of the tyrosine kinase inhibitor NSC 680410 against human leukemia and glioblastoma cell lines.

Cancer chemotherapy and pharmacology 20021201

Potassium-induced increase in renal kallikrein secretion is attenuated in dissected renal connecting tubules of young spontaneously hypertensive rats.

International immunopharmacology 20021201

[Supramolecular chemistry of multinuclear zinc(II) complexes in aqueous solution].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20021201

Synthesis and binding affinities of 5-(3-pyridinyl)- and 5-(3-quinolinyl)-4-azahomoadamantanes to alpha7 nicotinic acetylcholine receptors.

Farmaco (Societa chimica italiana : 1989) 20021201

Geometry for self-assembling of spherical hydrocarbon cages with methane thiolates on au(111).

Journal of the American Chemical Society 20021113

Solid-state and solution studies of a tetrameric capsule and its guests.

Angewandte Chemie (International ed. in English) 20021018

Nanoscale 1,3,5,7-tetrasubstituted adamantanes and p-substituted tetraphenyl-methanes for AFM applications.

Organic letters 20021017

A novel soluble analog of the HIV-1 fusion cofactor, globotriaosylceramide (Gb(3)), eliminates the cholesterol requirement for high affinity gp120/Gb(3) interaction.

Journal of lipid research 20021001

Neuroprotective effects of a novel non-receptor-binding estrogen analogue: in vitro and in vivo analysis.

Stroke 20021001

FTIR spectra and normal-mode analysis of a tetranuclear manganese adamantane-like complex in two electrochemically prepared oxidation states: relevance to the oxygen-evolving complex of photosystem II.

Journal of the American Chemical Society 20020918

2-Substituted 4-(thio)chromenone 6-O-sulfamates: potent inhibitors of human steroid sulfatase.

Journal of medicinal chemistry 20020912

H-coupled electron transfer in alkane C-h activations with halogen electrophiles.

Journal of the American Chemical Society 20020911

A monomeric selenium(IV) diimide and a dimeric seleninylamine.

Chemical communications (Cambridge, England) 20020907

Fluorescent probes for cytochrome p450 structural characterization and inhibitor screening.

Journal of the American Chemical Society 20020904

Metal-switching and self-inclusion of functional cavitands.

Journal of the American Chemical Society 20020904

Stimulation of TNF-alpha production by 2-(1-adamantylamino)-6-methylpyridine (AdAMP) - a novel immunomodulator with potential application in tumour immunotherapy.

Cancer chemotherapy and pharmacology 20020901

[Comparison of the anticonvulsant activity of organic mono- and di-cations and their potential to inhibit NMDA and AMPA glutamate receptors].

Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20020901

Synthesis and antimicrobial activity of new adamantane derivatives III.

Farmaco (Societa chimica italiana : 1989) 20020801

New selective inhibitors of cytochromes P450 2B and their application to antimutagenesis of tamoxifen.

Archives of biochemistry and biophysics 20020701

Structural properties of a series of photochromic fluorinated indolylfulgides.

Acta crystallographica. Section C, Crystal structure communications 20020701

Mechanism of asymmetric hydrogenation by rhodium complexes with unsymmetrical P-chirogenic bisphosphine ligands.

Chirality 20020701

Neurotensin phase-shifts the firing rate rhythm of neurons in the rat suprachiasmatic nuclei in vitro.

The European journal of neuroscience 20020701

Unique dual fluorescence of sterically congested hexaalkyl benzenehexacarboxylates: mechanism and application to viscosity probing.

Journal of the American Chemical Society 20020619

Comprehensive study of the methyl effect on the solvolysis rates of bridgehead derivatives.

Journal of the American Chemical Society 20020612

Novel selective PDE4 inhibitors. 3. In vivo antiinflammatory activity of a new series of N-substituted cis-tetra- and cis-hexahydrophthalazinones.

Journal of medicinal chemistry 20020606

Novel selective phosphodiesterase (PDE4) inhibitors. 4. Resolution, absolute configuration, and PDE4 inhibitory activity of cis-tetra- and cis-hexahydrophthalazinones.

Journal of medicinal chemistry 20020606

Dimethyladamantylmaleimide-induced in vitro and in vivo growth inhibition of human colon cancer Colo205 cells.

Anti-cancer drugs 20020601

Anti-viral drugs in continuous ambulatory peritoneal dialysis (CAPD).

Minerva urologica e nefrologica = The Italian journal of urology and nephrology 20020601

The neurotensin receptor antagonist SR 142948A blocks the efflux of dopamine evoked in nucleus accumbens by neurotensin ejection into the ventral tegmental area.

Naunyn-Schmiedeberg's archives of pharmacology 20020601

Evaluation of GluR2 subunit involvement in AMPA receptor function of neonatal rat hypoglossal motoneurons.

The European journal of neuroscience 20020601

A preliminary approach to nonenolizable beta,beta-tricarbonyls: assembly of a hyperevolutin prototype.

The Journal of organic chemistry 20020503

New dendrimer-peptide host-guest complexes: towards dendrimers as peptide carriers.

Chembiochem : a European journal of chemical biology 20020503

Effects of neurotensin receptor antagonism on latent inhibition in Sprague-Dawley rats.

Psychopharmacology 20020501

Triorganostannylation of halo- and dihaloadamantanes and 5-chloro-2-adamantanone in liquid ammonia by the S(RN)1 mechanism. Relative reactivity of nucleophiles and bridgehead halides.

The Journal of organic chemistry 20020419

Acetylide-bridged organometallic oligomers via the photochemical metathesis of methyl-iron(II) complexes.

Journal of the American Chemical Society 20020410

Pairwise exchanges of oxo and imido groups in rhenium(VII) compounds.

Inorganic chemistry 20020408

The estrogen receptor is not essential for all estrogen neuroprotection: new evidence from a new analog.

Neurobiology of disease 20020401

Adamantyl tenocyclidines--adjuvant therapy in poisoning with organophosphorus compounds and carbamates.

Archives of toxicology 20020401

Transformation of mutagenic aromatic amines into non-mutagenic species by alkyl substituents. Part II: alkylation far away from the amino function.

Mutation research 20020325

Stains, labels and detection strategies for nucleic acids assays.

Annals of clinical biochemistry 20020301

Synthesis and antiviral activity evaluation of some new 6-substituted 3-(1-adamantyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles.

Farmaco (Societa chimica italiana : 1989) 20020301

DFT analysis of the activation and breaking of the Mo-N bond in a (mu-nitrido)dimolybdenum complex: is molybdenum tris(thiolate) an elusive intermediate?

Inorganic chemistry 20020225

Intrinsic (gas phase) thermodynamic stability of 2-adamantyl cation. Its bearing on the solvolysis rates of 2-adamantyl derivatives.

The Journal of organic chemistry 20020222

A cuboctahedral supramolecular capsule by 4:4 self-assembly of Tris(Zn(II)-cyclen) and trianionic trithiocyanurate in aqueous solution at neutral pH (cyclen=1,4,7,10-tetraazacyclododecane).

Chemistry (Weinheim an der Bergstrasse, Germany) 20020215

Regiochemistry of the photostimulated reaction of the phthalimide anion with 1-iodoadamantane and tert-butylmercury chloride by the S(RN)1 mechanism.

The Journal of organic chemistry 20020208

Role of kallikrein-kininogen system in insulin-stimulated glucose transport after muscle contractions.

Journal of applied physiology (Bethesda, Md. : 1985) 20020201

Unique property of some synthetic retinoids: activation of the aryl hydrocarbon receptor pathway.

Molecular pharmacology 20020201

The actions of a D-1 agonist in MPTP treated primates show dependence on both D-1 and D-2 receptor function and tolerance on repeated administration.

Journal of neural transmission (Vienna, Austria : 1996) 20020201

Synthesis and optimization of a new family of type 3 17 beta-hydroxysteroid dehydrogenase inhibitors by parallel liquid-phase chemistry.

Journal of medicinal chemistry 20020131

Palladium-catalyzed arylation of malonates and cyanoesters using sterically hindered trialkyl- and ferrocenyldialkylphosphine ligands.

The Journal of organic chemistry 20020125

Effects of the incorporation of IBTM beta-turn mimetics into the dipeptoid CCK(1) receptor agonist PD 170292.

Bioorganic & medicinal chemistry letters 20020121

Effects of the Bcr/abl kinase inhibitors STI571 and adaphostin (NSC 680410) on chronic myelogenous leukemia cells in vitro.

Blood 20020115

The influence of substitution at aromatic part of 1,2,3,4-tetrahydroisoquinoline on in vitro and in vivo 5-HT(1A)/5-HT(2A) receptor activities of its 1-adamantoyloaminoalkyl derivatives.

Bioorganic & medicinal chemistry 20020101

Electrophoretic behavior of adamantane derivatives possessing antiviral activity and their determination by capillary zone electrophoresis with indirect detection.

Electrophoresis 20020101

Comparison of interactions of D1-like agonists, SKF 81297, SKF 82958 and A-77636, with cocaine: locomotor activity and drug discrimination studies in rodents.

Psychopharmacology 20020101

The estimation of melting points and fusion enthalpies using experimental solubilities, estimated total phase change entropies, and mobile order and disorder theory.

Journal of chemical information and computer sciences 20020101

Structural characteristics of ionotropic glutamate receptors as identified by channel blockade.

Neuroscience and behavioral physiology 20020101

Development of a nonviral gene delivery vehicle for systemic application.

Bioconjugate chemistry 20020101

[Comparison of anti-amnesia properties of NMDA-receptor 'fast' blockers and polyamines].

Eksperimental'naia i klinicheskaia farmakologiia 20020101

The effects of diphenhydramine and SR142948A on periaqueductal gray neurons and on the interactions between the medial preoptic nucleus and the periaqueductal gray.

Neuroscience 20020101

Effects of some trivalent metal ions on the fluoride-induced chemiluminescence from a phenylphosphate-substituted dioxetane Lumigen PPD.

Luminescence : the journal of biological and chemical luminescence 20020101

(R)-3-Amidinophenylalanine-derived inhibitors of factor Xa with a novel active-site binding mode.

Biological chemistry 20020101

Synthesis and antimicrobial activity evaluation of some new adamantane derivatives.

Arzneimittel-Forschung 20020101

[Effect of ladasten on proliferative activity and apoptosis in peripheral blood T-lymphocytes ].

Eksperimental'naia i klinicheskaia farmakologiia 20020101

Synthesis and biological properties of S-adamantylated heterocyclic compounds.

Acta poloniae pharmaceutica 20020101

Synthesis of adamantyl naphthalene diimide and its interaction with double stranded DNA.

Nucleic acids research. Supplement (2001) 20020101

Rapid determination of soluble epoxide hydrolase inhibitors in rat hepatic microsomes by high-performance liquid chromatography with electrospray tandem mass spectrometry.

Analytical biochemistry 20011215

Effects of cholecystokinin tetrapeptide (CCK(4)) and anxiolytic drugs on the electrically evoked [(3)H]5-hydroxytryptamine outflow from rat cortical slices.

Brain research 20011213

Is the tert-butyl chloride solvolysis the most misunderstood reaction in organic chemistry? Evidence against nucleophilic solvent participation in the tert-butyl chloride transition state and for increased hydrogen bond donation to the 1-adamantyl chloride solvolysis transition state.

Journal of the American Chemical Society 20011107

Hydrocarbon activation. Synthesis of beta-cycloalkyl (di)nitriles through photosensitized conjugate radical addition.

The Journal of organic chemistry 20011102

Long-range magnetic interactions in trans-1,4-cyclohexylene- and 1,3-adamantylene-bis(p-nitrenylbenzene) by pi-sigma-pi hyperconjugation.

Organic letters 20011018

Differential responses to ATPgammaS in the mesenteric and hindlimb vascular bed of the cat.

Life sciences 20011012

Metal-directed formation of three-dimensional M(3)L(2) trigonal-bipyramidal cages.

Organic letters 20011004

The aglycone of sulfogalactolipids can alter the sulfate ester substitution position required for hsc70 recognition.

Carbohydrate research 20010928

Iron polynitroporphyrins bearing up to eight beta-nitro groups as interesting new catalysts for H2O2-dependent hydrocarbon oxidation: unusual regioselectivity in hydroxylation of alkoxybenzenes.

Chemical communications (Cambridge, England) 20010921

Alkyl exchange reactions of organocobalt porphyrins. A bimolecular homolytic substitution reaction.

Journal of the American Chemical Society 20010919

Novel synthesis of alkenes via triethylborane-induced free-radical reactions of alkyl iodides and beta-nitrostyrenes.

The Journal of organic chemistry 20010907

Analysis of responses to hAmylin, hCGRP, and hADM in isolated resistance arteries from the mesenteric vascular bed of the rat.

Peptides 20010901

Monodithiolene molybdenum(V, VI) complexes: a structural analogue of the oxidized active site of the sulfite oxidase enzyme family.

Journal of the American Chemical Society 20010829

Substitution and oxidation reactions of bis(dithiolene)tungsten complexes of potential relevance to enzyme sites.

Inorganic chemistry 20010827

Switching of a macromolecular helicity for visual distinction of molecular recognition events.

Journal of the American Chemical Society 20010822

Novel 3-(2-adamantyl)pyrrolidines with potent activity against influenza A virus-identification of aminoadamantane derivatives bearing two pharmacophoric amine groups.

Bioorganic & medicinal chemistry letters 20010820

Water-soluble adamantane-terminated dendrimers possessing a rhenium core.

The Journal of organic chemistry 20010810

On the origin of selective nitrous oxide N-N bond cleavage by three-coordinate molybdenum(III) complexes.

Journal of the American Chemical Society 20010801

[Structure of glutamate receptor ion channels and mechanisms of their blockade by organic cations].

Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20010801

The effect of neighboring 1- and 2-adamantyl group substitution on the conformations and stereodynamics of N-methylpiperidine. Dynamic NMR spectroscopy and molecular mechanics calculations.

The Journal of organic chemistry 20010727

Sn-zeolite beta as a heterogeneous chemoselective catalyst for Baeyer-Villiger oxidations.

Nature 20010726

Origin of diastereofacial selectivity in tertiary 2-adamantyl cations.

Journal of the American Chemical Society 20010704

Interactions of synthetic estrogens with human estrogen receptors.

The Journal of endocrinology 20010701

Synthesis and modulation of cytokine production by two new adamantane substituted acyclic desmuramyldipeptide analogs.

Die Pharmazie 20010701

K(ATP) channels predominantly regulate conduit vessel tone in normoxic cat pulmonary arteries in vivo.

European journal of pharmacology 20010622

Neurotensin excitation of serotonergic neurons in the rat nucleus raphe magnus: ionic and molecular mechanisms.

Neuropharmacology 20010601

Endogenous neurotensin down-regulates dopamine efflux in the nucleus accumbens as revealed by SR-142948A, a selective neurotensin receptor antagonist.

Journal of neurochemistry 20010601

Inhibition of human multidrug resistance P-glycoprotein 1 by analogues of a potent delta-opioid antagonist.

Brain research 20010525

Cavitand-porphyrins.

Journal of the American Chemical Society 20010523

Adamantylaminopyrimidines and -pyridines are potent inducers of tumor necrosis factor-alpha.

Bioorganic & medicinal chemistry letters 20010507

Studies of the synthesis of SSZ-25 zeolite in a 'mixed-template' system.

Chemistry (Weinheim an der Bergstrasse, Germany) 20010504

Nonpeptide cholecystokinin-2 receptor agonists.

Journal of medicinal chemistry 20010412

Rewarding and locomotor-activating effects of direct dopamine receptor agonists are augmented by chronic food restriction in rats.

Psychopharmacology 20010401

A high pressure FT-IR spectroscopic study of phase transitions in 1-chloro- and 1-bromoadamantane.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20010401

Influence of alkyl substitution on the gas-phase stability of 1-adamantyl cation and on the solvent effects in the solvolysis of 1-bromoadamantane.

The Journal of organic chemistry 20010323

Synthesis and properties of new thiourea-functionalized poly(propylene imine) dendrimers and their role as hosts for urea functionalized guests.

The Journal of organic chemistry 20010323

Effect of cyclodextrin on the intramolecular catalysis of amide hydrolysis.

The Journal of organic chemistry 20010309

Bis(dithiolene)molybdenum analogues relevant to the DMSO reductase enzyme family: synthesis, structures, and oxygen atom transfer reactions and kinetics.

Journal of the American Chemical Society 20010307

Comparative effects of scopolamine and quinpirole on the striatal fos expression induced by stimulation of D(1) dopamine receptors in the rat.

Brain research 20010302

Biorelevant dissolution testing to predict the plasma profile of lipophilic drugs after oral administration.

Pharmaceutical research 20010301

Hydroxylation of camphor by reduced oxy-cytochrome P450cam: mechanistic implications of EPR and ENDOR studies of catalytic intermediates in native and mutant enzymes.

Journal of the American Chemical Society 20010221

Capture of a single molecule in a nanocavity.

Science (New York, N.Y.) 20010126

Enhanced neurotensin neurotransmission is involved in the clinically relevant behavioral effects of antipsychotic drugs: evidence from animal models of sensorimotor gating.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20010115

Copper(I)-catalyzed [2 + 2] photocycloadditions with tethered linkers: synthesis of syn-photodimers of dicyclopentadienes.

The Journal of organic chemistry 20010112

New analogues of bradykinin containing a conformationally restricted dipeptide fragment in their molecules.

The journal of peptide research : official journal of the American Peptide Society 20010101

An optimized method for the chemiluminescent detection of alkaline phosphatase levels during osteodifferentiation by bone morphogenetic protein 2.

Journal of cellular biochemistry 20010101

Organic halide electroreduction on silver.

Annali di chimica 20010101

Pharmacological analysis of the subunit composition of the AMPA receptor in hippocampal neurons.

Neuroscience and behavioral physiology 20010101

Therapeutical effect of modified adamantane copolymer compounds: study of molecular mechanisms.

Acta biochimica Polonica 20010101

[Effect of the potential antiparkinsonian agent adamantane derivative on ion channels of NMDA glutamate receptors].

Eksperimental'naia i klinicheskaia farmakologiia 20010101

[Immunotropic activity of a potential antiparkinson agent himantane].

Eksperimental'naia i klinicheskaia farmakologiia 20010101

Effect of adamantanone derivative possessing anti-HIV properties on the redox processes in the cytochrome P-450 system.

Doklady. Biochemistry and biophysics 20010101

[Effect of the new potential anti-Parkinson agent, hymantane, on levels of monoamines and their metabolites in rat striatum (a microdialysis study)].

Eksperimental'naia i klinicheskaia farmakologiia 20010101

Synthesis, structure and tumour necrosis factor-alpha production-enhancing properties of novel adamantylamino heterocyclic derivatives.

Anti-cancer drug design 20010101

Neurotensin modulates the electrical activity of frog pituitary melanotropes via activation of a G-protein-coupled receptor pharmacologically related to both the NTS1 and nts2 receptors of mammals.

Neuroendocrinology 20001201

Synthesis, antitumor activity, and anti-HIV-1 testing of certain heterocyclic systems containing an adamantane nucleus.

Archiv der Pharmazie 20001001

[A comparative study of the central H-cholinergic-blocking and NMDA-blocking actions of MK-801, memantin, amantadine, pyrilen and IEM-1754 in experiments on intact rats].

Eksperimental'naia i klinicheskaia farmakologiia 20000101

The role of cholecystokinin (CCK), CCK-A or CCK-B receptor antagonists in the spontaneous preference for drugs of abuse (alcohol or cocaine) in naive rats.

Methods and findings in experimental and clinical pharmacology 19981001

How to overcome resistance of influenza A viruses against adamantane derivatives.

Antiviral research 19980201

Second generation 'peptoid' CCK-B receptor antagonists: identification and development of N-(adamantyloxycarbonyl)-alpha-methyl-(R)-tryptophan derivative (CI-1015) with an improved pharmacokinetic profile.

Journal of medicinal chemistry 19980101

Anticonvulsant phenytoinergic pharmacophores and anti-HIV activity--preliminary evidence for the dual requirement of the 4-aminophthalimide platform and the N-(1-adamantyl) substitution for antiviral properties.

Life sciences 19980101

Kinins are implicated of the hypotensive effect of acidic fibroblast growth factor.

European journal of medical research 19970728

Biochemical and pharmacological activities of SR 142948A, a new potent neurotensin receptor antagonist.

The Journal of pharmacology and experimental therapeutics 19970201

Synthesis and antiviral activity evaluation of some new aminoadamantane derivatives. 2.

Journal of medicinal chemistry 19960816

Selective in vivo antagonism of pinacidil-induced hypotension by the guanidine U37883A in anesthetized rats.

Pharmacology 19941201

Synthesis and antiviral activity evaluation of some aminoadamantane derivatives.

Journal of medicinal chemistry 19940902

New C-protective group for peptide synthesis. Application of 2-(1-adamantyl)-propanol-2 esters.

International journal of peptide and protein research 19930901

Synthesis, antifungal, antibacterial and antiviral effects of some adamantaneketoxime ethers.

Farmaco (Societa chimica italiana : 1989) 19930801

Microbial oxidation of adamantanone by Pseudomonas putida carrying the camphor catabolic plasmid.

Biochemical and biophysical research communications 19920814

Isolation of a heptapeptide Val-Val-Tyr-Pro-Trp-Thr-Gln (valorphin) with some opiate activity.

International journal of peptide and protein research 19920601

Synthesis and antiviral activity of metabolites of rimantadine.

Journal of medicinal chemistry 19900701

Rimantadine and seizures.

Annals of internal medicine 19890215

Combined interferon-alpha 2, rimantadine hydrochloride, and ribavirin inhibition of influenza virus replication in vitro.

Antimicrobial agents and chemotherapy 19840101

Comparative toxicity of amantadine hydrochloride and rimantadine hydrochloride in healthy adults.

Antimicrobial agents and chemotherapy 19810201

Influence of membrane (M) protein on influenza A virus virion transcriptase activity in vitro and its susceptibility to rimantadine.

Journal of virology 19800201

Adamantylthiourea derivatives as antiviral agents.

Journal of medicinal chemistry 19790801

281-23-2 | Adamantane

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