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27826-74-0 | Uridine, 2'-deoxy-5-propyl-
CAS No: 27826-74-0 Catalog No: AG002UUE MDL No:
Product Description
Catalog Number:
AG002UUE
Chemical Name:
Uridine, 2'-deoxy-5-propyl-
CAS Number:
27826-74-0
Molecular Formula:
C12H18N2O5
Molecular Weight:
270.2817
IUPAC Name:
1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-propylpyrimidine-2,4-dione
InChI:
InChI=1S/C12H18N2O5/c1-2-3-7-5-14(12(18)13-11(7)17)10-4-8(16)9(6-15)19-10/h5,8-10,15-16H,2-4,6H2,1H3,(H,13,17,18)/t8-,9+,10+/m0/s1
InChI Key:
MBERTAKFBYOAHR-IVZWLZJFSA-N
SMILES:
CCCc1cn([C@H]2C[C@@H]([C@H](O2)CO)O)c(=O)[nH]c1=O
Properties
Complexity:
409
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
3
Defined Bond Stereocenter Count:
0
Exact Mass:
270.122g/mol
Formal Charge:
0
Heavy Atom Count:
19
Hydrogen Bond Acceptor Count:
5
Hydrogen Bond Donor Count:
3
Isotope Atom Count:
0
Molecular Weight:
270.285g/mol
Monoisotopic Mass:
270.122g/mol
Rotatable Bond Count:
4
Topological Polar Surface Area:
99.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.2
Literature
| Title | Journal |
|---|---|
| 2'-Deoxy-5-propynyluridine: a nucleoside with two conformations in the asymmetric unit. | Acta crystallographica. Section C, Crystal structure communications 20091201 |
| Anti-(herpes simplex virus) activity of 4'-thio-2'-deoxyuridines: a biochemical investigation for viral and cellular target enzymes. | The Biochemical journal 20001015 |
| Synthesis and antitumor and antiviral properties of 5-alkyl-2'-deoxyuridines, 3',5'-cyclic monophosphates, and neutral cyclic triesters. | Journal of medicinal chemistry 19860401 |
| In vitro susceptibility of varicella-zoster virus to E-5-(2-bromovinyl)-2'-deoxyuridine and related compounds. | Antimicrobial agents and chemotherapy 19820101 |
| Anti-herpes simplex virus and anti-human cell growth activity of E-5-propenyl-2'-deoxyuridine and the concept of selective protection in antivirus chemotherapy. | Antimicrobial agents and chemotherapy 19801201 |
| The 5'-monophosphates of 5-propyl- and 5-ethyl-2'-deoxyuridine do not inhibit the replication of deoxythymidine kinase deficient (TK-) mutants of herpes simplex virus. | Biochemical pharmacology 19801015 |
| Relative potencies of different anti-herpes agents in the topical treatment of cutaneous herpes simplex virus infection of athymic nude mice. | Antimicrobial agents and chemotherapy 19791101 |
| (E)-5-(2-Bromovinyl)-2'-deoxyuridine: a potent and selective anti-herpes agent. | Proceedings of the National Academy of Sciences of the United States of America 19790601 |
| 5-Propyl-2'-deoxyuridine: a specific anti-herpes agent. | Antimicrobial agents and chemotherapy 19780301 |
| Antiviral action and cellular toxicity of four thymidine analogues: 5-ethyl-,5-vinyl-, 5-propyl-, and 5-allyl-2'- deoxyuridine. | Antimicrobial agents and chemotherapy 19760701 |
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