CAS 27790-75-6 | Pyridine, dihydro- | CAS Number 27790-75-6

Title	Journal
Quantitative high-throughput profiling of environmental chemicals and drugs that modulate farnesoid X receptor.	Scientific reports 20140101
Nitric oxide inhibits androgen receptor-mediated collagen production in human gingival fibroblasts.	Journal of periodontal research 20121201
Synthesis and SAR of b-annulated 1,4-dihydropyridines define cardiomyogenic compounds as novel inhibitors of TGFβ signaling.	Journal of medicinal chemistry 20121126
A facile four component protocol for the synthesis of dihydropyridine derivatives.	Organic & biomolecular chemistry 20121014
Design, solvent free synthesis, and antimicrobial evaluation of 1,4 dihydropyridines.	Bioorganic & medicinal chemistry letters 20120915
Elucidating the pre- and post-nuclear intracellular processing of 1,4-dihydropyridine based gene delivery carriers.	Journal of controlled release : official journal of the Controlled Release Society 20120820
Small molecule-mediated TGF-β type II receptor degradation promotes cardiomyogenesis in embryonic stem cells.	Cell stem cell 20120803
Remarkably fast and selective aromatization of Hantzsch esters with MoOCl4 and MoCl5: a chemical model for possible biologically relevant properties of molybdenum-containing enzymes.	Bioorganic & medicinal chemistry letters 20120601
Discovery and evaluation of selective N-type calcium channel blockers: 6-unsubstituted-1,4-dihydropyridine-5-carboxylic acid derivatives.	Bioorganic & medicinal chemistry letters 20120601
Facile photoreduction of graphene oxide by an NAD(P)H model: Hantzsch 1,4-dihydropyridine.	Langmuir : the ACS journal of surfaces and colloids 20120529
Reactivators of acetylcholinesterase inhibited by organophosphorus nerve agents.	Accounts of chemical research 20120515
Synthesis of 5-alkylated barbituric acids and 3-alkylated indoles via microwave-assisted three-component reactions in solvent-free conditions using Hantzsch 1,4-dihydropyridines as reducing agents.	Molecular diversity 20120501
Dihydropyridine calcium channel blockers and the progression of parkinsonism.	Annals of neurology 20120301
How do dihydropyridine and nondihydropyridine CCBs differ?	JAAPA : official journal of the American Academy of Physician Assistants 20120301
Application of electron conformational-genetic algorithm approach to 1,4-dihydropyridines as calcium channel antagonists: pharmacophore identification and bioactivity prediction.	Journal of molecular modeling 20120101
Cloudy peritoneal fluid attributable to non-dihydropyridine calcium channel blocker.	Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20120101
1,4-Dihydropyridine scaffold in medicinal chemistry, the story so far and perspectives (part 2): action in other targets and antitargets.	Current medicinal chemistry 20120101
Calcium channel antagonist exposures reported to the Poisons Information Center Erfurt.	European journal of internal medicine 20111201
Distinct properties of amlodipine and nicardipine block of the voltage-dependent Ca2+ channels Cav1.2 and Cav2.1 and the mutant channels Cav1.2/dihydropyridine insensitive and Cav2.1/dihydropyridine sensitive.	European journal of pharmacology 20111116
[4 + 2] Cyclocondensation reactions of tungsten-dihydropyridine complexes and the generation of tri- and tetrasubstituted piperidines.	Journal of the American Chemical Society 20111116
Hantzsch reaction: synthesis and characterization of some new 1,4-dihydropyridine derivatives as potent antimicrobial and antioxidant agents.	European journal of medicinal chemistry 20111101
Reciprocal dihydropyridine and ryanodine receptor interactions in skeletal muscle activation.	Journal of muscle research and cell motility 20111101
Intramolecular C-H···O hydrogen bonding in 1,4-dihydropyridine derivatives.	Molecules (Basel, Switzerland) 20110919
Synthesis and biological evaluation of some novel N-aryl-1,4-dihydropyridines as potential antitubercular agents.	Bioorganic & medicinal chemistry letters 20110915
Tetrodotoxin-, dihydropyridine-, and riluzole-resistant persistent inward current: novel sodium channels in rodent spinal neurons.	Journal of neurophysiology 20110901
Effect of 4-aryl-2-methyl-5-nitro-1,4-dihydropyridine-3-carboxylates on the guinea pig papillary muscle and isolated human vena saphena magna that is used for coronary artery bypass grafting.	European journal of medicinal chemistry 20110901
Influence of dihydropyridine calcium antagonist nitrendipine on benzo(a)pyrene-induced oxidative stress.	Archives of pharmacal research 20110701
Cystic fibrosis: a new target for 4-Imidazo[2,1-b]thiazole-1,4-dihydropyridines.	Journal of medicinal chemistry 20110609
Selective dihydropyiridine compounds facilitate the clearance of β-amyloid across the blood-brain barrier.	European journal of pharmacology 20110601
Asymmetric synthesis and biological evaluations of (+)- and (-)-6-dimethoxymethyl-1,4-dihydropyridine-3-carboxylic acid derivatives blocking N-type calcium channels.	Bioorganic & medicinal chemistry letters 20110601
Molecular docking studies and in vitro screening of new dihydropyridine derivatives as human MRP1 inhibitors.	Bioorganic & medicinal chemistry 20110515
Mechanism underlying the block of human Cav3.2 T-type Ca2+ channels by benidipine, a dihydropyridine Ca2+ channel blocker.	Life sciences 20110509
Synthesis, antibacterial and antimycobacterial activities of some new 4-aryl/heteroaryl-2,6-dimethyl-3,5-bis-N-(aryl)-carbamoyl-1,4-dihydropyridines.	European journal of medicinal chemistry 20110501
Use of dihydropyridine calcium channel blockers in the management of hypertension in Eastern Asians: a scientific statement from the Asian Pacific Heart Association.	Hypertension research : official journal of the Japanese Society of Hypertension 20110401
Enantioselective organocatalytic aza-ene-type domino reaction leading to 1,4-dihydropyridines.	The Journal of organic chemistry 20110318
Ultrasound-enhanced one-pot synthesis of 3-(Het)arylmethyl-4-hydroxycoumarins in water.	Ultrasonics sonochemistry 20110301
Calcium inhibits dihydropyridine-stimulated increases in opening and unitary conductance of a plant Ca²+ channel.	The Journal of membrane biology 20110301
Growth modulation of human cells in vitro by mild oxidative stress and 1,4-dihydropyridine derivative antioxidants.	Collegium antropologicum 20110301
Synthesis and anticoagulant activity of a new series of 1,4-dihydropyridine derivatives.	European journal of medicinal chemistry 20110201
Comparative study of taurine and tauropyrone: GABA receptor binding, mitochondrial processes and behaviour.	The Journal of pharmacy and pharmacology 20110201
Two 1,4-dihydropyridine derivatives with potential calcium-channel antagonist activity.	Acta crystallographica. Section C, Crystal structure communications 20110201
Identification of dihydropyridines that reduce cellular tau levels.	Chemical communications (Cambridge, England) 20110107
Anti-breast cancer activity of some novel 1,2-dihydropyridine, thiophene and thiazole derivatives.	European journal of medicinal chemistry 20110101
Effect of a dihydropyridine-type calcium channel blocker on vascular remodeling after experimental balloon angioplasty.	Cardiovascular & hematological agents in medicinal chemistry 20110101
Mapping of dihydropyridine binding residues in a less sensitive invertebrate L-type calcium channel (LCa v 1).	Channels (Austin, Tex.) 20110101
New evidence of a dihydropyridine-activated cationic channel in the MDCK cell line.	Nephron. Physiology 20110101
Design and synthesis of some novel hydrazide, 1,2-dihydropyridine, chromene derivatives carrying biologically active sulfone moieties with potential anticancer activity.	Arzneimittel-Forschung 20110101
1,4-Dihydropyridine scaffold in medicinal chemistry, the story so far and perspectives (part 1): action in ion channels and GPCRs.	Current medicinal chemistry 20110101
[Derivatives of 1,4-dihydropyridines as 'priviledged structures' and their pharmacological potential].	Kardiologia polska 20110101
Synthesis, structural and conformational properties, and gas phase reactivity of 1,4-dihydropyridine ester and ketone derivatives.	Organic & biomolecular chemistry 20101207
Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1.	Nature 20101202
Catalytic asymmetric synthesis of both enantiomers of 4‑substituted 1,4-dihydropyridines with the use of bifunctional thiourea-ammonium salts bearing different counterions.	Molecules (Basel, Switzerland) 20101115
Synthesis of new tripodal Hantzsch 1,4-dihydropyridines under solvent-free condition and their conversion to the corresponding tripodal pyridines.	Molecular diversity 20101101
Brain-specific delivery of naproxen using different carrier systems.	Archiv der Pharmazie 20101101
Exceptional thermal stability in a supramolecular organic framework: porosity and gas storage.	Journal of the American Chemical Society 20101020
Insertion of pyridine into the calcium allyl bond: regioselective 1,4-dihydropyridine formation and C-H bond activation.	Angewandte Chemie (International ed. in English) 20101011
PAC1hop receptor activation facilitates catecholamine secretion selectively through 2-APB-sensitive Ca(2+) channels in PC12 cells.	Cellular signalling 20101001
Synthesis of a library of 5,6-unsubstituted 1,4-dihydropyridines based on a one-pot 4CR/elimination process and their application to the generation of structurally diverse fused nitrogen heterocycles.	Journal of combinatorial chemistry 20100913
Synthesis and biological evaluation of novel hybrid chalcone derivatives as vasorelaxant agents.	European journal of medicinal chemistry 20100901
Flutamide inhibits nifedipine- and interleukin-1 beta-induced collagen overproduction in gingival fibroblasts.	Journal of periodontal research 20100801
Novel structure-activity relationships and selectivity profiling of cage dimeric 1,4-dihydropyridines as multidrug resistance (MDR) modulators.	Bioorganic & medicinal chemistry 20100715
Facile and efficient aromatization of 1,4-dihydropyridines with M(NO3)2.XH2O, TNCB, TBAP and HMTAI and preparation of deuterium labeled dehydronifedipine from nifedipine-d3.	Bioorganic & medicinal chemistry letters 20100615
Dihydropyridine-insensitive calcium currents contribute to function of small cerebral arteries.	Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20100601
Design and synthesis of 1,4-dihydropyridine derivatives as BACE-1 inhibitors.	European journal of medicinal chemistry 20100601
Delayed diagnosis of primary hyperaldosteronism.	BMJ (Clinical research ed.) 20100525
Antagonism of 4-substituted 1,4-dihydropyridine-3,5-dicarboxylates toward voltage-dependent L-type Ca2+ channels Ca V 1.3 and Ca V 1.2.	Bioorganic & medicinal chemistry 20100501
L-type calcium channel blockers and Parkinson disease in Denmark.	Annals of neurology 20100501
A region of N-type Ca(2+) channel critical for blockade by the dihydropyridine amlodipine.	European journal of pharmacology 20100425
Design, multicomponent synthesis, and bioactivities of novel neonicotinoid analogues with 1,4-dihydropyridine scaffold.	Journal of agricultural and food chemistry 20100310
Interaction of (benzylidene-hydrazono)-1,4-dihydropyridines with beta-amyloid, acetylcholine, and butyrylcholine esterases.	Bioorganic & medicinal chemistry 20100301
Synthesis and biological evaluation of N-aryl-1,4-dihydropyridines as novel antidyslipidemic and antioxidant agents.	European journal of medicinal chemistry 20100201
Synthesis and biological activity of the calcium modulator (R) and (S)-3-methyl 5-pentyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.	Bioorganic & medicinal chemistry letters 20100201
Clevidipine for severe hypertension in acute heart failure: a VELOCITY trial analysis.	Congestive heart failure (Greenwich, Conn.) 20100101
Betablockers in combination with other antihypertensives.	Indian heart journal 20100101
L-proline-catalyzed synthesis of highly functionalized multisubstituted 1,4-dihydropyridines.	Organic & biomolecular chemistry 20091207
Synthesis, coordination chemistry and bonding of strong N-donor ligands incorporating the 1H-pyridin-(2E)-ylidene (PYE) motif.	Chemistry (Weinheim an der Bergstrasse, Germany) 20091026
Prediction of photosensitivity of 1,4-dihydropyridine antihypertensives by quantitative structure-property relationship.	Talanta 20091015
Aryl bridged 1-hydroxypyridin-2-one: effect of the bridge on the Eu(III) sensitization process.	Inorganic chemistry 20091005
Effects of 5-acetyl(carbamoyl)-6-methylsulfanyl-1,4-dihydropyridine-5-carbonitriles on rat liver mitochondrial function.	Toxicology in vitro : an international journal published in association with BIBRA 20091001
[H2O2 oxidation of 1,4-dihydropyridines over Mg2+ ion exchanged clinoptilolite and solventless solid state acid decomposition of ester to 3,5-pyridinedicarboxylic acid].	Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20091001
Suppression of formalin-induced nociception by cilnidipine, a voltage-dependent calcium channel blocker.	Biological & pharmaceutical bulletin 20091001
Exploring catalyst and solvent effects in the multicomponent synthesis of pyridine-3,5-dicarbonitriles.	The Journal of organic chemistry 20090918
Oxidative aromatization of 1,4-dihydropyridines and pyrazolines using HbA-H(2)O(2): An efficient biomimetic catalyst system providing metabolites of drug candidates.	Bioorganic & medicinal chemistry letters 20090801
Structural model for dihydropyridine binding to L-type calcium channels.	The Journal of biological chemistry 20090710
Dihydropyridine- and voltage-sensitive Ca2+ entry in human parathyroid cells.	Experimental physiology 20090701
Five different profiles of dihydropyridines in blocking T-type Ca(2+) channel subtypes (Ca(v)3.1 (alpha(1G)), Ca(v)3.2 (alpha(1H)), and Ca(v)3.3 (alpha(1I))) expressed in Xenopus oocytes.	European journal of pharmacology 20090624
Assessment and use of two silicon carbide multi-well plates for library synthesis and proteolytic digests using microwave heating.	Organic & biomolecular chemistry 20090607
Evidence for regulation of mitochondrial function by the L-type Ca2+ channel in ventricular myocytes.	Journal of molecular and cellular cardiology 20090601
Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease.	Journal of medicinal chemistry 20090514
Dihydropyridine C-glycoconjugates by organocatalytic Hantzsch cyclocondensation. Stereoselective synthesis of alpha-threofuranose C-nucleoside enantiomers.	Organic & biomolecular chemistry 20090507
Expression of voltage-activated calcium channels in the early zebrafish embryo.	Zygote (Cambridge, England) 20090501
Genetic polymorphisms of L-type calcium channel alpha1C and alpha1D subunit genes are associated with sensitivity to the antihypertensive effects of L-type dihydropyridine calcium-channel blockers.	Circulation journal : official journal of the Japanese Circulation Society 20090401
Isolation and pharmacological characterization of fatty acids from saw palmetto extract.	Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20090401
Synthesis and docking studies of new 1,4-dihydropyridines containing 4-(5)-Chloro-2-ethyl-5-(4)-imidazolyl substituent as novel calcium channel agonist.	Archives of pharmacal research 20090401
[Perspectives of inhibition of multidrug resistance during cancer chemotherapy, in vitro and in vivo experiments].	Orvosi hetilap 20090329
1-Malonyl-1,4-dihydropyridine as a novel carrier for specific delivery of drugs to the brain.	Bioorganic & medicinal chemistry 20090215
Expression and 1,4-dihydropyridine-binding properties of brain L-type calcium channel isoforms.	Molecular pharmacology 20090201
Rationale, study design and implementation of the COLM study: the combination of OLMesartan and calcium channel blocker or diuretic in high-risk elderly hypertensive patients.	Hypertension research : official journal of the Japanese Society of Hypertension 20090201
Differential sensitivities of CaV1.2 IIS5-S6 mutants to 1,4-dihydropyridine analogs.	European journal of pharmacology 20090114
Dihydropyridine inhibition of the glycine receptor: subunit selectivity and a molecular determinant of inhibition.	Neuropharmacology 20090101
How to extend the use of grid-based interaction energy maps from chemistry to biotopics.	ChemMedChem 20090101
The regio- and stereoselective synthesis of trans-2,3-dihydropyridine N-oxides and piperidines.	Angewandte Chemie (International ed. in English) 20090101
Bis-enaminone based parallel solution-phase synthesis of 1,4-dihydropyridine derivatives.	Journal of combinatorial chemistry 20090101
Modulation of cellular defense processes in human lymphocytes in vitro by a 1,4-dihydropyridine derivative.	Mutation research 20090101
Synthesis, characterization and anticonvulsant activity evaluation of some 1,4-dihydropyridines and 3,5-(substituted)oxycarbonyl-1,4-dihydro-2,6-dimethyl-N-[2-(4-sulfamoylphenylamino)-acetyl]-4-(substituted)pyridines.	Acta poloniae pharmaceutica 20090101
Spermatogenesis following discontinuation of calcium channel blocker amlodipine in rats.	Journal of Ayub Medical College, Abbottabad : JAMC 20090101
Sustainable synthetic methods: domino construction of dihydropyridin-4-ones and beta-amino esters in aqueous ethanol.	Organic letters 20081120
Calcium-channel blockers reduce the antiplatelet effect of clopidogrel.	Journal of the American College of Cardiology 20081104
Structure-activity relationships of 1,4-dihydropyridines that act as enhancers of the vanilloid receptor 1 (TRPV1).	Bioorganic & medicinal chemistry 20081015
A highly efficient biomimetic aromatization of Hantzsch-1,4-dihydropyridines with t-butylhydroperoxide, catalysed by iron(III) phthalocyanine chloride.	Bioorganic & medicinal chemistry 20081015
The structure-activity relationship study on 2-, 5-, and 6-position of the water soluble 1,4-dihydropyridine derivatives blocking N-type calcium channels.	Bioorganic & medicinal chemistry letters 20080901
One-pot synthesis of highly functionalized pyridines via a rhodium carbenoid induced ring expansion of isoxazoles.	Journal of the American Chemical Society 20080709
The solvent-free synthesis of 1,4-dihydropyridines under ultrasound irradiation without catalyst.	Ultrasonics sonochemistry 20080701
Effective management of hypertension with dihydropyridine calcium channel blocker-based combination therapy in patients at high cardiovascular risk.	International journal of clinical practice 20080501
A genetic screen for dihydropyridine (DHP)-resistant worms reveals new residues required for DHP-blockage of mammalian calcium channels.	PLoS genetics 20080501
Evaluation of anticancer effects of newly synthesized dihydropyridine derivatives in comparison to verapamil and doxorubicin on T47D parental and resistant cell lines in vitro.	Cell biology and toxicology 20080401
[Interaction of 1,4-dihydropyridines with ion channels].	Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20080401
Imidazo[2,1-b]thiazole system: a scaffold endowing dihydropyridines with selective cardiodepressant activity.	Journal of medicinal chemistry 20080327
Synthesis of unsymmetrical substituted 1,4-dihydropyridines through thermal and microwave assisted [4+2] cycloadditions of 1-azadienes and allenic esters.	The Journal of organic chemistry 20080321
Synthesis of 6-amino-1,4-dihydropyridines that prevent calcium overload and neuronal death.	European journal of medicinal chemistry 20080301
A number of marketed dihydropyridine calcium channel blockers have mineralocorticoid receptor antagonist activity.	Hypertension (Dallas, Tex. : 1979) 20080301
Structure-activity relationships of receptor binding of 1,4-dihydropyridine derivatives.	Biological & pharmaceutical bulletin 20080301
Sulfonic acid functionalized silica: an efficient heterogeneous catalyst for a three-component synthesis of 1,4-dihydropyridines under solvent-free conditions.	Chemical & pharmaceutical bulletin 20080301
Ultrasound-assisted photochemical oxidation of unsymmetrically substituted 1,4-dihydropyridines.	Ultrasonics sonochemistry 20080201
Inclusion of patients who overdose with dihydropyridine calcium channel blockers would potentially increase clinical utility of hyperglycemia.	Critical care medicine 20080201
Relationship between lipophilicities of 1,4-dihydropyridine derivatives and pharmacokinetic interaction strengths with grapefruit juice.	Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080101
Analysis of dihydropyridine calcium channel blockers using negative ion photoionization mass spectrometry.	Journal of chromatographic science 20080101
Microwave-assisted combinatorial synthesis of hexa-substituted 1,4-dihydropyridines scaffolds using one-pot two-step multicomponent reaction followed by a S-alkylation.	Journal of combinatorial chemistry 20080101
L-type Ca2+ channel function is linked to dystrophin expression in mammalian muscle.	PloS one 20080101
Hantzsch synthesis of 2,6-dimethyl-3,5-dimethoxycarbonyl-4-(o-methoxyphenyl)-1,4-dihydropyridine; a novel cyclisation leading to an unusual formation of 1-amino-2-methoxy-carbonyl-3,5-bis(o-methoxyphenyl)-4-oxa-cyclohexan-1-ene.	Molecules (Basel, Switzerland) 20071126
[Hypertension as a source of cognitive regression, or dementia].	Nederlands tijdschrift voor geneeskunde 20071103
9-phenyl-10-methylacridinium: a highly efficient and reusable organocatalyst for mild aromatization of 1,4-dihydropyridines by molecular oxygen.	The Journal of organic chemistry 20071026
Synthesis, QSAR and calcium channel antagonist activity of new 1,4-dihydropyridine derivatives containing 1-methyl-4,5-dichloroimidazolyl substituents.	Archiv der Pharmazie 20071001
Domino reaction of 3-(2-formylphenoxy)propenoates and amines: a novel synthesis of 1,4-dihydropyridines from salicaldehydes, ethyl propiolate, and amines.	The Journal of organic chemistry 20070928
Are differences in calcium antagonists relevant across all stages of nephropathy or only proteinuric nephropathy?	Current opinion in nephrology and hypertension 20070901
Autocrine activation of ion currents in the two-cell mouse embryo.	Experimental cell research 20070801
Structure-activity relationship of 1,4-dihydropyridines as potentiators of the cystic fibrosis transmembrane conductance regulator chloride channel.	Molecular pharmacology 20070701
Calcicludine binding to the outer pore of L-type calcium channels is allosterically coupled to dihydropyridine binding.	Biochemistry 20070626
Oxidation of C4-hydroxyphenyl 1,4-dihydropyridines in dimethylsulfoxide and its reactivity towards alkylperoxyl radicals in aqueous medium.	Bioorganic & medicinal chemistry 20070615
Oxidative aromatization of Hantzsch 1,4-dihydropyridines in the presence of mixed-addenda vanadomolybdophosphate heteropolyacid, H6PMo9V3O40.	Bioorganic & medicinal chemistry letters 20070615
Analyses by GC-MS and GC-MS-MS of the Hantzsch synthesis products using hydroxy- and methoxy-aromatic aldehydes.	Journal of pharmaceutical and biomedical analysis 20070509
The effect of ionizing radiation of 1,4-dihydropyridine derivatives in the solid state.	Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070501
One-step synthesis of heterocyclic privileged medicinal scaffolds by a multicomponent reaction of malononitrile with aldehydes and thiols.	The Journal of organic chemistry 20070427
G1 cell cycle arrest by amlodipine, a dihydropyridine Ca2+ channel blocker, in human epidermoid carcinoma A431 cells.	Biochemical pharmacology 20070401
N-methyl-(R)-3-(tert-butyl)-sulfinyl-1,4-dihydropyridine: a novel NADH model compound.	Molecules (Basel, Switzerland) 20070312
A convenient and efficient protocol for oxidative aromatization of Hantzsch 1,4-dihydropyridines using benzyltriphenylphosphonium peroxymonosulfate under almost neutral reaction conditions.	Bioorganic & medicinal chemistry letters 20070215
Maturation of rat cerebellar Purkinje cells reveals an atypical Ca2+ channel current that is inhibited by omega-agatoxin IVA and the dihydropyridine (-)-(S)-Bay K8644.	The Journal of physiology 20070201
Distinct effects of atypical 1,4-dihydropyridines on 1-methyl-4-phenylpyridinium-induced toxicity.	Cell biochemistry and function 20070101
Photophysics and photochemical studies of 1,4-dihydropyridine derivatives.	Photochemistry and photobiology 20070101
Recent advances in alpha1-adrenoreceptor antagonists as pharmacological tools and therapeutic agents.	Current topics in medicinal chemistry 20070101
Calcium channels blockers and progression of kidney disease.	Renal failure 20070101
[Hypotensive efficacy and tolerability of combination of dihydropyridine and non-dihydropyridine calcium antagonists in the treatment of patients with arterial hypertension].	Kardiologiia 20070101
Novel multipotent tacrine-dihydropyridine hybrids with improved acetylcholinesterase inhibitory and neuroprotective activities as potential drugs for the treatment of Alzheimer's disease.	Journal of medicinal chemistry 20061228
Regulation of the homologous two-component systems KvgAS and KvhAS in Klebsiella pneumoniae CG43.	Journal of biochemistry 20061101
The actions of azelnidipine, a dihydropyridine-derivative Ca antagonist, on voltage-dependent Ba2+ currents in guinea-pig vascular smooth muscle.	British journal of pharmacology 20061101
Physicochemical characteristics of novel P-glycoprotein inhibitors of the cage dimeric 1,4-dihydropyridine type.	Medicinal chemistry (Shariqah (United Arab Emirates)) 20061101
Synthesis of a naphthyridone p38 MAP kinase inhibitor.	The Journal of organic chemistry 20061027
Rhes expression in pancreatic beta-cells is regulated by efaroxan in a calcium-dependent process.	Biochemical and biophysical research communications 20061020
Randomized study of angiotensin II type 1 receptor blocker vs dihydropiridine calcium antagonist for the treatment of paroxysmal atrial fibrillation in patients with hypertension.	Circulation journal : official journal of the Japanese Circulation Society 20061001
Switch between charge transfer and local excited states in 4-aminophenyl-substituted Hantzsch 1,4-dihydropyridine induced by pH change and transition metal ions.	Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20061001
Nitro radical anion formation from nitrofuryl substituted 1,4-dihydropyridine derivatives in mixed and non-aqueous media.	Bioelectrochemistry (Amsterdam, Netherlands) 20060901
Cancer cell permeability-glycoprotein as a target of MDR reverters: possible role of novel dihydropyridine derivatives.	Current drug targets 20060801
QSAR study of 1,4-dihydropyridine calcium channel antagonists based on gene expression programming.	Bioorganic & medicinal chemistry 20060715
Fused 1,4-dihydropyridines as potential calcium modulatory compounds.	Mini reviews in medicinal chemistry 20060701
Design, synthesis, and calcium channel antagonist activity of new 1,4-dihydropyridines containing 4-(5)-chloro-2-ethyl-5-(4)-imidazolyl substituent.	Archiv der Pharmazie 20060601
The cGMP/protein kinase G pathway contributes to dihydropyridine-sensitive calcium response and cytokine production in TH2 lymphocytes.	The Journal of biological chemistry 20060505
Biological evaluation of bishydroxymethyl-substituted cage dimeric 1,4-dihydropyridines as a novel class of p-glycoprotein modulating agents in cancer cells.	Journal of medicinal chemistry 20060504
Rapid and efficient oxidation of Hantzsch 1,4-dihydropyridines with sodium periodate catalyzed by manganese (III) Schiff base complexes.	Bioorganic & medicinal chemistry 20060415
Mild and efficient oxidation of Hantzsch 1,4-dihydropyridines with sodium periodate catalyzed by a new polystyrene-bound Mn(TPP)Cl.	Bioorganic & medicinal chemistry letters 20060401
Cocrystals of diastereoisomers of 1,4-dihydropyridine derivatives.	Acta crystallographica. Section C, Crystal structure communications 20060401
Solid phase synthesis of a redox delivery system with the aim of targeting peptides into the brain.	Organic & biomolecular chemistry 20060307
Structure-activity relationship study of 1,4-dihydropyridine derivatives blocking N-type calcium channels.	Bioorganic & medicinal chemistry letters 20060215
HPLC method for analysis of a new 1,4-dihydropyridine: application to pharmacokinetic study in rabbit.	Journal of pharmaceutical and biomedical analysis 20060213
Does the MOSES trial establish superiority of AT1-receptor blockers over dihydropyridine/calcium antagonists in secondary stroke prevention?	Stroke 20060201
Instability of calcium channel antagonists during sample preparation for LC-MS-MS analysis of serum samples.	Forensic science international 20060106
The L-type calcium channel blockers, hantzsch 1,4-dihydropyridines, are not peroxyl radical-trapping, chain-breaking antioxidants.	Chemical research in toxicology 20060101
Study of the interaction of 1,4-dihydropyridine derivatives with glucocorticoid hormone receptors from the rat liver.	Pharmacological reports : PR 20060101
Photostabilization of 1,4-dihydropyridine antihypertensives by incorporation into beta-cyclodextrin and liposomes.	Journal of nanoscience and nanotechnology 20060101
Antihypertensive 1,4-dihydropyridines as correctors of the cystic fibrosis transmembrane conductance regulator channel gating defect caused by cystic fibrosis mutations.	Molecular pharmacology 20051201
Substantial reaction between histamine and malondialdehyde: a new observation of carbonyl stress.	Neuro endocrinology letters 20051201
A 1,4-dihydropyridine derivative reduces DNA damage and stimulates DNA repair in human cells in vitro.	Mutation research 20051110
Parallel, solution phase synthesis of dihydropyridine miticides via a versatile multicomponent reaction.	Combinatorial chemistry & high throughput screening 20051101
Cerebrocrast promotes the cotransport of H+ and Cl- in rat liver mitochondria.	Mitochondrion 20051001
PHARMAC responds to Stewart Mann on dihydropyridine calcium channel antagonists.	The New Zealand medical journal 20050812
Biomimetic oxidation of Hantzsch 1,4-dihydropyridines with tetra-n-butylammonium periodate catalyzed by tetraphenylporphyrinatomanganese(III) chloride [Mn(TPP)Cl].	Bioorganic & medicinal chemistry letters 20050701
1,4-Dihydropyridine derivatives as calcium channel modulators: the role of 3-methoxy-flavone moiety.	Bioorganic & medicinal chemistry 20050516
An approach for measuring in vivo cerebral redox states using the oxidative conversion of dihydropyridine to pyridinium ion and the metabolic trapping principle.	Free radical biology & medicine 20050501
Effect of compression on interaction between 1,4-dihydropyridine compounds and lactose monohydrate.	Chemical & pharmaceutical bulletin 20050501
The relationship between magnitude of proteinuria reduction and risk of end-stage renal disease: results of the African American study of kidney disease and hypertension.	Archives of internal medicine 20050425
BENEDICT in the treatment of hypertension.	Current hypertension reports 20050401
Emergence of a R-type Ca2+ channel (CaV 2.3) contributes to cerebral artery constriction after subarachnoid hemorrhage.	Circulation research 20050304
Intraglomerular inhibition: signaling mechanisms of an olfactory microcircuit.	Nature neuroscience 20050301
Hantzsch 1,4-dihydropyridines containing a diazen-1-ium-1,2-diolate nitric oxide donor moiety to study calcium channel antagonist structure-activity relationships and nitric oxide release.	Bioorganic & medicinal chemistry 20050301
Substituted thiazolamide coupled to a redox delivery system: a new gamma-secretase inhibitor with enhanced pharmacokinetic profile.	Organic & biomolecular chemistry 20050221
Applying pattern recognition methods and structure property correlations to determine drug carrier potential of nicotinic acid and analogize to dihydropyridine.	European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20050101
Case studies in hypertension. Dihydropyridine/nondihydropyridine calcium channel blocker combination therapy.	Journal of clinical hypertension (Greenwich, Conn.) 20050101
[Toxicological analysis of selected 1,4-dihydropyridine calcium channel blockers in the diagnosis of intoxications].	Archiwum medycyny sadowej i kryminologii 20050101
QSAR and classification study of 1,4-dihydropyridine calcium channel antagonists based on least squares support vector machines.	Molecular pharmaceutics 20050101
Improvement of the chromatographic separation of several 1,4-dihydropyridines calcium channel antagonist drugs by experimental design.	Journal of chromatographic science 20050101
Opposite effects of a single IIIS5 mutation on phenylalkylamine and dihydropyridine interaction with L-type Ca2+ channels.	The Journal of biological chemistry 20041231
Isosteric N-arylpiperazine replacements in a series of dihydropyridine NPY1 receptor antagonists.	Bioorganic & medicinal chemistry letters 20041220
Selective glucocorticoid receptor nonsteroidal ligands completely antagonize the dexamethasone mediated induction of enzymes involved in gluconeogenesis and glutamine metabolism.	The Journal of steroid biochemistry and molecular biology 20041201
Drug treatment of essential hypertension: the case for initial combination therapy.	International journal of clinical practice 20041001
Dioleoyl phosphatidylethanolamine and PEG-lipid conjugates modify DNA delivery mediated by 1,4-dihydropyridine amphiphiles.	Journal of controlled release : official journal of the Controlled Release Society 20040914
Application of ab initio theory to QSAR study of 1,4-dihydropyridine-based calcium channel blockers using GA-MLR and PC-GA-ANN procedures.	Journal of computational chemistry 20040901
Dihydropyridine calcium channel blockers: basic pharmacological similarities but fundamental therapeutic differences.	Journal of hypertension 20040901
Synthesis and biological evaluation of 1,4-dihydropyridine calcium channel modulators having a diazen-1-ium-1,2-diolate nitric oxide donor moiety for the potential treatment of congestive heart failure.	Bioorganic & medicinal chemistry 20040715
1,4-dihydropyridines: reactivity of nitrosoaryl and nitroaryl derivatives with alkylperoxyl radicals and ABTS radical cation.	Free radical research 20040701
Proliferation of cultured human gingival fibroblasts caused by isradipine, a dihydropyridine-derivative calcium antagonist.	European journal of medical research 20040630
Screening for dihydropyridine calcium channel blockers in plasma by automated solid-phase extraction and liquid chromatography/tandem mass spectrometry.	Journal of mass spectrometry : JMS 20040601
Marrubenol interacts with the phenylalkylamine binding site of the L-type calcium channel.	European journal of pharmacology 20040525
Structural effects on the reactivity 1,4-dihydropyridines with alkylperoxyl radicals and ABTS radical cation.	Bioorganic & medicinal chemistry 20040501
Acute and sustained effects of dihydropyridine-type calcium channel antagonists on oxidative stress in systemic sclerosis.	The American journal of medicine 20040501
Metabolic formation of DHP-derived DNA adducts from a representative otonecine type pyrrolizidine alkaloid clivorine and the extract of Ligularia hodgsonnii hook.	Chemical research in toxicology 20040501
Molecular mechanisms of vasoselectivity of the 1,4-dihydropyridine lercanidipine.	British journal of pharmacology 20040501
HPLC enantiomer separation of a chiral 1,4-dihydropyridine monocarboxylic acid.	Journal of pharmaceutical and biomedical analysis 20040416
Polyphenolic antioxidants mimic the effects of 1,4-dihydropyridines on neurotensin receptor function in PC3 cells.	The Journal of pharmacology and experimental therapeutics 20040401
Cloning of the Cav 1.3 (alpha1D) L-type Ca2+ channel from mouse and its expression in the liver.	International journal of molecular medicine 20040401
Dihydropiridines mechanism of action in striatal isolated nerve endings: comparison with omega-agatoxin IVA.	Neurochemical research 20040401
Effects of immediate versus delayed antihypertensive therapy on outcome in the Systolic Hypertension in Europe Trial.	Journal of hypertension 20040401
Synthetic strategy toward skeletal diversity via solid-supported, otherwise unstable reactive intermediates.	Angewandte Chemie (International ed. in English) 20040319
Disruption of intestinal motility by a calcium channel-stimulating autoantibody in type 1 diabetes.	Gastroenterology 20040301
Dihydropyridine neuropeptide Y Y1 receptor antagonists 2. bioisosteric urea replacements.	Bioorganic & medicinal chemistry 20040115
Inhibition of type A GABA receptors by L-type calcium channel blockers.	Neuroscience 20040101
Effect of new and known 1,4-dihydropyridine derivatives on blood glucose levels in normal and streptozotocin-induced diabetic rats.	Cell biochemistry and function 20040101
[Radiation modulating properties of derivates of 1,4-dihydropyridine and 1,2,3,4,5,6,7,8,9,10-decahydroacridine-1,8 dione].	Radiatsionnaia biologiia, radioecologiia 20040101
Quantitative structure-activity relationship studies on some series of calcium channel blockers.	Molecular diversity 20040101
Evaluation of a simple carrier molecule to enhance drug penetration of dermal layers by utilizing multivariate methods, structure property correlations, and continuous system modeling.	Physiological chemistry and physics and medical NMR 20040101
Modified cardiovascular L-type channels in mice lacking the voltage-dependent Ca2+ channel beta3 subunit.	The Journal of biological chemistry 20031031
Glucose-lowering in a db/db mouse model by dihydropyridine diacid glycogen phosphorylase inhibitors.	Bioorganic & medicinal chemistry letters 20031020
Synthesis and anticonvulsant activity of novel 1-substituted-1,2-dihydro-pyridazine-3,6-diones.	Biological & pharmaceutical bulletin 20031001
Clinical and economic consequences of reference pricing for dihydropyridine calcium channel blockers.	Clinical pharmacology and therapeutics 20031001
Synthesis, in vitro and in vivo evaluation of a delivery system for targeting anticancer drugs to the brain.	Archiv der Pharmazie 20031001
Modulation of manganese currents by 1, 4-dihydropyridines, isoproterenol and forskolin in rabbit ventricular cells.	Pflugers Archiv : European journal of physiology 20030901
Hypothyroidism does not affect the dihydropyridine sensitivity of precontracted murine uterus.	Canadian journal of physiology and pharmacology 20030901
L-type calcium channel activation up-regulates the mRNAs for two different sodium channel alpha subunits (Nav1.2 and Nav1.3) in rat pituitary GH3 cells.	Brain research. Molecular brain research 20030819
DHP-insensitive L-type-like Ca channel of ascidian acquires sensitivity to DHP with single amino acid change in domain III P-region.	FEBS letters 20030814
Key roles of Phe1112 and Ser1115 in the pore-forming IIIS5-S6 linker of L-type Ca2+ channel alpha1C subunit (CaV 1.2) in binding of dihydropyridines and action of Ca2+ channel agonists.	Molecular pharmacology 20030801
Cav1.4alpha1 subunits can form slowly inactivating dihydropyridine-sensitive L-type Ca2+ channels lacking Ca2+-dependent inactivation.	The Journal of neuroscience : the official journal of the Society for Neuroscience 20030709
[125I]A-312110, a novel high-affinity 1,4-dihydropyridine ATP-sensitive K+ channel opener: characterization and pharmacology of binding.	Molecular pharmacology 20030701
Enantiomeric separation by HPLC of 1,4-dihydropyridines with vancomycin as chiral selector.	Chirality 20030601
1,4-Dihydropyridines as calcium channel ligands and privileged structures.	Cellular and molecular neurobiology 20030601
The L-type Ca2+-channel subunits alpha1C and beta2 are not downregulated in atrial myocardium of patients with chronic atrial fibrillation.	Journal of molecular and cellular cardiology 20030501
New carrier for specific delivery of drugs to the brain.	Bioorganic & medicinal chemistry 20030417
Ca v 1.3 is preferentially coupled to glucose-stimulated insulin secretion in the pancreatic beta-cell line INS-1.	The Journal of pharmacology and experimental therapeutics 20030401
Inhibition of cAMP signalling cascade-mediated Ca2+ influx by a prothoracicostatic peptide (Mas-MIP I) via dihydropyridine-sensitive Ca2+ channels in the prothoracic glands of the silkworm, Bombyx mori.	Insect biochemistry and molecular biology 20030201
Location of ryanodine and dihydropyridine receptors in frog myocardium.	Biophysical journal 20030201
Functional interaction of auxiliary subunits and synaptic proteins with Ca(v)1.3 may impart hair cell Ca2+ current properties.	Journal of neurophysiology 20030201
Reactivity of 1,4-dihydropyridines toward alkyl, alkylperoxyl radicals, and ABTS radical cation.	Chemical research in toxicology 20030201
Modulation of L-type Ca2+ channels in neonatal rat heart by a novel Ca2+ channel agonist.	Canadian journal of physiology and pharmacology 20030201
Pharmacological characterization of a 1,4-dihydropyridine analogue, 9-(3,4-dichlorophenyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydro-1,8(2H,5H)-acridinedione (A-184209) as a novelK(ATP) channel inhibitor.	British journal of pharmacology 20030101
Comparison between neural networks (NN) and principal component analysis (PCA): structure activity relationships of 1,4-dihydropyridine calcium channel antagonists (nifedipine analogues).	Journal of chemical information and computer sciences 20030101
Atheroprotective effects of long-acting dihydropyridine-type calcium channel blockers: evidence from clinical trials and basic scientific research.	Cerebrovascular diseases (Basel, Switzerland) 20030101
Does QTc interval predict the response to beta-blockers and calcium channel blockers in hypertensives?	Heart disease (Hagerstown, Md.) 20030101
The ascidian dihydropyridine-resistant calcium channel as the prototype of chordate L-type calcium channel.	Neuro-Signals 20030101
Photo- and radiostability of some 1,4-dihydropyridine derivatives in the solid state.	Acta poloniae pharmaceutica 20030101
Incidence of pedal edema formation with dihydropyridine calcium channel blockers: issues and practical significance.	Journal of clinical hypertension (Greenwich, Conn.) 20030101
Risk of myocardial infarction with combination antihypertensive regimens including a dihydropyridine calcium channel blocker in hypertensive diabetics.	Journal of managed care pharmacy : JMCP 20030101
Decoration of dihydropyrimidine and dihydropyridine scaffolds with sugars via Biginelli and Hantzsch multicomponent reactions: an efficient entry to a collection of artificial nucleosides.	Molecular diversity 20030101
MRS study of the interaction of dihydropyridines with lipid molecules in phosphatidylcholine vesicles.	Physiological chemistry and physics and medical NMR 20030101
[Innovative molecular transformation using optically active alpha-amino acids].	Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20021101
Passive transfer of Lambert-Eaton syndrome to mice induces dihydropyridine sensitivity of neuromuscular transmission.	The Journal of physiology 20020901
Heart rate in hypertensive patients treated with ACE inhibitors and long-acting dihydropyridine calcium antagonists.	Journal of cardiovascular pharmacology 20020801
Effects of UV and visible light on cyanobacteria at the cellular level.	Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20020801
Face-selective addition to a cation-pi complex of a pyridinium salt: synthesis of chiral 1,4-dihydropyridines.	Journal of the American Chemical Society 20020717
Extracellular and intracellular factors influencing gene transfection mediated by 1,4-dihydropyridine amphiphiles.	European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20020601
Angiotensin converting enzyme inhibition and dihydropyridine calcium channel blockade in the treatment of left ventricular hypertrophy in arterial hypertension.	Minerva cardioangiologica 20020601
A novel water-soluble Hantzsch 1,4-dihydropyridine compound that functions in biological processes through NADH regeneration.	The Journal of organic chemistry 20020517
Productive trapping of NAD-type radicals. Non-biomimetic reduction of pyridinium salts.	Chemical communications (Cambridge, England) 20020421
Enhanced vascular effects of the Ca(2+) channel agonist Bay K 8644 in pregnant rabbits.	American journal of physiology. Regulatory, integrative and comparative physiology 20020401
A spectroscopic investigation of hydrogen bond patterns in crystalline and amorphous phases in dihydropyridine calcium channel blockers.	Pharmaceutical research 20020401
The effect of temperature on hydrogen bonding in crystalline and amorphous phases in dihydropyrine calcium channel blockers.	Pharmaceutical research 20020401
Impact of an ACE inhibitor and calcium antagonist on microalbuminuria and lipid subfractions in type 2 diabetes: a randomised, multi-centre pilot study.	Journal of human hypertension 20020301
The effect of ionizing radiation on some derivatives of 1,4-dihydropyridine in the solid state.	International journal of pharmaceutics 20020221
Calcium involvement in the luminescence control of three ophiuroid species (Echinodermata).	Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020201
Effect of acyl chain length and branching on the enantioselectivity of Candida rugosa lipase in the kinetic resolution of 4-(2-difluoromethoxyphenyl)-substituted 1,4-dihydropyridine 3,5-diesters.	The Journal of organic chemistry 20020125
[Clastogenicity of ethyl methanesulfonate and dimethyl terephthalate in the micronucleus test and ways for its modification].	TSitologiia i genetika 20020101
Comparison of losartan with ACE inhibitors and dihydropyridine calcium channel antagonists: a pilot study of prescription-event monitoring in Japan.	Drug safety 20020101
Treatment of hypertensive retinopathy.	Survey of ophthalmology 20020101
Neuroprotective effect of treatment with calcium antagonists on hypertensive retina.	Clinical and experimental hypertension (New York, N.Y. : 1993) 20020101
Gas chromatography/mass spectrometric study of non-commercial C-4-substituted 1,4-dihydropyridines and their oxidized derivatives.	Rapid communications in mass spectrometry : RCM 20020101
A prokaryotic voltage-gated sodium channel.	Science (New York, N.Y.) 20011214
A component of excitation-contraction coupling triggered in the absence of the T671-L690 and L720-Q765 regions of the II-III loop of the dihydropyridine receptor alpha(1s) pore subunit.	Biophysical journal 20011201
Dihydropyridine calcium-channel blockers for antihypertensive treatment in older patients--evidence from the Systolic Hypertension in Europe Trial.	South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20011201
Independent modulation of L-type Ca2+ channel in guinea pig ventricular cells by nitrendipine and isoproterenol.	Japanese heart journal 20011101
Torquoselectivity induced by lone-pair conjugation in the electrocyclic reactions of 1-azapolyenes.	The Journal of organic chemistry 20011005
Dihydropyridine calcium channel blockers and peripheral side effects.	Journal of human hypertension 20011001
Role of dihydropyridine-sensitive calcium channels in the regulation of norepinephrine release in hypertension.	Journal of cardiovascular pharmacology 20011001
Mechanism of action of angiotensin II in human isolated subcutaneous resistance arteries.	British journal of pharmacology 20010901
Laragh's lessons in pathophysiology and clinical pearls for treating hypertension.	American journal of hypertension 20010901
Pilot study to evaluate a water displacement technique to compare effects of diuretics and ACE inhibitors to alleviate lower extremity edema due to dihydropyridine calcium antagonists.	American journal of hypertension 20010901
3-Methyl 5-isopropyl 2-methoxyiminomethyl-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.	Acta crystallographica. Section C, Crystal structure communications 20010901
Neuronal Ca(V)1.3alpha(1) L-type channels activate at relatively hyperpolarized membrane potentials and are incompletely inhibited by dihydropyridines.	The Journal of neuroscience : the official journal of the Society for Neuroscience 20010815
Treatment advances for cocaine-induced ischemic stroke: focus on dihydropyridine-class calcium channel antagonists.	The American journal of psychiatry 20010801
Stereoselective trans- and cis-dihydroxylations of 2H-pyranyl and dihydropyridinyl heterocycles synthesized from formal [3 + 3]-cycloaddition reactions of alpha,beta-unsaturated iminium ions with 1,3-dicarbonyl equivalents.	Organic letters 20010712
Protein kinase C-mediated calcium entry dependent upon dihydropyridine sensitive channels: a T cell receptor-coupled signaling pathway involved in IL-4 synthesis.	FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010701
Functional expression and characterization of a voltage-gated CaV1.3 (alpha1D) calcium channel subunit from an insulin-secreting cell line.	Molecular endocrinology (Baltimore, Md.) 20010701
Searching for balanced hybrid NO-donor 1,4-dihydropyridines with basic properties.	Pharmaceutical research 20010701
Influence of treatment with Ca(2+) antagonists on cerebral vasculature of spontaneously hypertensive rats.	Mechanisms of ageing and development 20010601
Fundamental Ca2+ signaling mechanisms in mouse dendritic cells: CRAC is the major Ca2+ entry pathway.	Journal of immunology (Baltimore, Md. : 1950) 20010515
Nifedipine-activated Ca(2+) permeability in newborn rat cortical collecting duct cells in primary culture.	American journal of physiology. Cell physiology 20010501
Ca(2+) entry into primary cultured pig coronary smooth muscle cells after previous store depletion by repetitive P2Y purinoceptor stimulation.	Cell calcium 20010501
Inhibition of ATP-induced surfactant exocytosis by dihydropyridine (DHP) derivatives: a non-stereospecific, photoactivated effect and independent of L-type Ca2+ channels.	Biochemical pharmacology 20010501
Comparative effects of selective T- and L-type calcium channel blockers in the remnant kidney model.	Hypertension (Dallas, Tex. : 1979) 20010501
Mechanism of dihydropyridine interaction with critical binding residues of L-type Ca2+ channel alpha 1 subunits.	The Journal of biological chemistry 20010420
Contribution of the plasmalemma to Ca2+ homeostasis in hair cells.	The Journal of neuroscience : the official journal of the Society for Neuroscience 20010415
Photoreaction of 2-halo-N-pyridinylbenzamide: intramolecular cyclization mechanism of phenyl radical assisted with n-complexation of chlorine radical.	The Journal of organic chemistry 20010406
Gadolinium prevents stretch-mediated contractile dysfunction in isolated papillary muscles.	American journal of physiology. Heart and circulatory physiology 20010301
Activation of purified cardiac ryanodine receptors by dihydropyridine agonists.	American journal of physiology. Heart and circulatory physiology 20010301
Comparative study on the vasorelaxant effects of three harmala alkaloids in vitro.	Japanese journal of pharmacology 20010301
Chronic nicotine alters NO signaling of Ca(2+) channels in cerebral arterioles.	Circulation research 20010216
Biophysical properties, pharmacology, and modulation of human, neuronal L-type (alpha(1D), Ca(V)1.3) voltage-dependent calcium currents.	Journal of neurophysiology 20010201
Pharmacologic management of atrial fibrillation: current therapeutic strategies.	American heart journal 20010201
Abnormality of calcium channel inhibitor released from fetal membranes in preterm labor.	American journal of obstetrics and gynecology 20010201
Studies on agents with mixed NO-dependent and calcium channel antagonistic vasodilating activities.	Pharmaceutical research 20010201
Calcium channel isoforms underlying synaptic transmission at embryonic Xenopus neuromuscular junctions.	The Journal of neuroscience : the official journal of the Society for Neuroscience 20010115
Calcium/calmodulin-dependent protein kinase type IV (CaMKIV) inhibits apoptosis induced by potassium deprivation in cerebellar granule neurons.	FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010101
Pranidipine, a 1,4-dihydropyridine calcium channel blocker that enhances nitric oxide-induced vascular relaxation.	Cardiovascular drug reviews 20010101
Expression of L-type calcium channels associated with postnatal development of skeletal muscle function in mouse.	Journal of muscle research and cell motility 20010101
High performance liquid chromatography of mebudipine: application to pharmacokinetic study.	Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20010101
[Effects of cardiovascular therapy on risk of the development of ischemia and myocardial infarction in the postoperative period in cancer patients with ischemic heart diseases].	Anesteziologiia i reanimatologiia 20010101
The learned symmetry concept in revealing quantitative structure-activity relationships with artificial neural networks.	SAR and QSAR in environmental research 20010101
Effects of isradipine, a dihydropyridine-class calcium channel antagonist, on D-methamphetamine-induced cognitive and physiological changes in humans.	Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20000501
Arterial responses in vitro and plasma digoxin immunoreactivity after losartan and enalapril treatments in experimental hypertension.	Pharmacology & toxicology 20000101
Inhibition of human cytochrome P450 enzymes by 1,4-dihydropyridine calcium antagonists: prediction of in vivo drug-drug interactions.	European journal of clinical pharmacology 20000101
Regional expression and functional characterization of the L-type Ca2+-channel in myocardium from patients with end-stage heart failure and in non-failing human hearts.	Journal of molecular and cellular cardiology 19990101
Interaction of 1,4-dihydropyridine and pyridine derivatives with adenosine receptors: selectivity for A3 receptors.	Journal of medicinal chemistry 19960719
Nifedipine. Dose-related increase in mortality in patients with coronary heart disease.	Circulation 19950901
Interaction of pinaverium (a quaternary ammonium compound) with 1,4-dihydropyridine binding sites in rat ileum smooth muscle.	British journal of pharmacology 19920201
Parathyroid hormone-stimulated cadmium accumulation in Madin-Darby canine kidney cells.	Toxicology and applied pharmacology 19910615
Endogenous opiate system and dihydropyridine-induced central regulation of sympathetic tone in rats.	European journal of pharmacology 19881206
Calcium currents in embryonic and neonatal mammalian skeletal muscle.	The Journal of general physiology 19880601
Central interactions between dihydropyridines and cholinergic systems in the control of blood pressure in rat.	Brain research 19871201
Renal effects of 1,4-dihydropyridines in animal models of hypertension and renal failure.	Journal of cardiovascular pharmacology 19870101

Elucidating the pre- and post-nuclear intracellular processing of 1,4-dihydropyridine based gene delivery carriers.

Journal of controlled release : official journal of the Controlled Release Society 20120820

Small molecule-mediated TGF-β type II receptor degradation promotes cardiomyogenesis in embryonic stem cells.

Cell stem cell 20120803

Remarkably fast and selective aromatization of Hantzsch esters with MoOCl4 and MoCl5: a chemical model for possible biologically relevant properties of molybdenum-containing enzymes.

Bioorganic & medicinal chemistry letters 20120601

Discovery and evaluation of selective N-type calcium channel blockers: 6-unsubstituted-1,4-dihydropyridine-5-carboxylic acid derivatives.

Bioorganic & medicinal chemistry letters 20120601

Facile photoreduction of graphene oxide by an NAD(P)H model: Hantzsch 1,4-dihydropyridine.

Langmuir : the ACS journal of surfaces and colloids 20120529

Reactivators of acetylcholinesterase inhibited by organophosphorus nerve agents.

Accounts of chemical research 20120515

Synthesis of 5-alkylated barbituric acids and 3-alkylated indoles via microwave-assisted three-component reactions in solvent-free conditions using Hantzsch 1,4-dihydropyridines as reducing agents.

Molecular diversity 20120501

Dihydropyridine calcium channel blockers and the progression of parkinsonism.

Annals of neurology 20120301

How do dihydropyridine and nondihydropyridine CCBs differ?

JAAPA : official journal of the American Academy of Physician Assistants 20120301

Application of electron conformational-genetic algorithm approach to 1,4-dihydropyridines as calcium channel antagonists: pharmacophore identification and bioactivity prediction.

Journal of molecular modeling 20120101

Cloudy peritoneal fluid attributable to non-dihydropyridine calcium channel blocker.

Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20120101

1,4-Dihydropyridine scaffold in medicinal chemistry, the story so far and perspectives (part 2): action in other targets and antitargets.

Current medicinal chemistry 20120101

Calcium channel antagonist exposures reported to the Poisons Information Center Erfurt.

European journal of internal medicine 20111201

Distinct properties of amlodipine and nicardipine block of the voltage-dependent Ca2+ channels Cav1.2 and Cav2.1 and the mutant channels Cav1.2/dihydropyridine insensitive and Cav2.1/dihydropyridine sensitive.

European journal of pharmacology 20111116

[4 + 2] Cyclocondensation reactions of tungsten-dihydropyridine complexes and the generation of tri- and tetrasubstituted piperidines.

Journal of the American Chemical Society 20111116

Hantzsch reaction: synthesis and characterization of some new 1,4-dihydropyridine derivatives as potent antimicrobial and antioxidant agents.

European journal of medicinal chemistry 20111101

Reciprocal dihydropyridine and ryanodine receptor interactions in skeletal muscle activation.

Journal of muscle research and cell motility 20111101

Intramolecular C-H···O hydrogen bonding in 1,4-dihydropyridine derivatives.

Molecules (Basel, Switzerland) 20110919

Synthesis and biological evaluation of some novel N-aryl-1,4-dihydropyridines as potential antitubercular agents.

Bioorganic & medicinal chemistry letters 20110915

Tetrodotoxin-, dihydropyridine-, and riluzole-resistant persistent inward current: novel sodium channels in rodent spinal neurons.

Journal of neurophysiology 20110901

Effect of 4-aryl-2-methyl-5-nitro-1,4-dihydropyridine-3-carboxylates on the guinea pig papillary muscle and isolated human vena saphena magna that is used for coronary artery bypass grafting.

European journal of medicinal chemistry 20110901

Influence of dihydropyridine calcium antagonist nitrendipine on benzo(a)pyrene-induced oxidative stress.

Archives of pharmacal research 20110701

Cystic fibrosis: a new target for 4-Imidazo[2,1-b]thiazole-1,4-dihydropyridines.

Journal of medicinal chemistry 20110609

Selective dihydropyiridine compounds facilitate the clearance of β-amyloid across the blood-brain barrier.

European journal of pharmacology 20110601

Asymmetric synthesis and biological evaluations of (+)- and (-)-6-dimethoxymethyl-1,4-dihydropyridine-3-carboxylic acid derivatives blocking N-type calcium channels.

Bioorganic & medicinal chemistry letters 20110601

Molecular docking studies and in vitro screening of new dihydropyridine derivatives as human MRP1 inhibitors.

Bioorganic & medicinal chemistry 20110515

Mechanism underlying the block of human Cav3.2 T-type Ca2+ channels by benidipine, a dihydropyridine Ca2+ channel blocker.

Life sciences 20110509

Synthesis, antibacterial and antimycobacterial activities of some new 4-aryl/heteroaryl-2,6-dimethyl-3,5-bis-N-(aryl)-carbamoyl-1,4-dihydropyridines.

European journal of medicinal chemistry 20110501

Use of dihydropyridine calcium channel blockers in the management of hypertension in Eastern Asians: a scientific statement from the Asian Pacific Heart Association.

Hypertension research : official journal of the Japanese Society of Hypertension 20110401

Enantioselective organocatalytic aza-ene-type domino reaction leading to 1,4-dihydropyridines.

The Journal of organic chemistry 20110318

Ultrasound-enhanced one-pot synthesis of 3-(Het)arylmethyl-4-hydroxycoumarins in water.

Ultrasonics sonochemistry 20110301

Calcium inhibits dihydropyridine-stimulated increases in opening and unitary conductance of a plant Ca²+ channel.

The Journal of membrane biology 20110301

Growth modulation of human cells in vitro by mild oxidative stress and 1,4-dihydropyridine derivative antioxidants.

Collegium antropologicum 20110301

Synthesis and anticoagulant activity of a new series of 1,4-dihydropyridine derivatives.

European journal of medicinal chemistry 20110201

Comparative study of taurine and tauropyrone: GABA receptor binding, mitochondrial processes and behaviour.

The Journal of pharmacy and pharmacology 20110201

Two 1,4-dihydropyridine derivatives with potential calcium-channel antagonist activity.

Acta crystallographica. Section C, Crystal structure communications 20110201

Identification of dihydropyridines that reduce cellular tau levels.

Chemical communications (Cambridge, England) 20110107

Anti-breast cancer activity of some novel 1,2-dihydropyridine, thiophene and thiazole derivatives.

European journal of medicinal chemistry 20110101

Effect of a dihydropyridine-type calcium channel blocker on vascular remodeling after experimental balloon angioplasty.

Cardiovascular & hematological agents in medicinal chemistry 20110101

Mapping of dihydropyridine binding residues in a less sensitive invertebrate L-type calcium channel (LCa v 1).

Channels (Austin, Tex.) 20110101

New evidence of a dihydropyridine-activated cationic channel in the MDCK cell line.

Nephron. Physiology 20110101

Design and synthesis of some novel hydrazide, 1,2-dihydropyridine, chromene derivatives carrying biologically active sulfone moieties with potential anticancer activity.

Arzneimittel-Forschung 20110101

1,4-Dihydropyridine scaffold in medicinal chemistry, the story so far and perspectives (part 1): action in ion channels and GPCRs.

Current medicinal chemistry 20110101

[Derivatives of 1,4-dihydropyridines as 'priviledged structures' and their pharmacological potential].

Kardiologia polska 20110101

Synthesis, structural and conformational properties, and gas phase reactivity of 1,4-dihydropyridine ester and ketone derivatives.

Organic & biomolecular chemistry 20101207

Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1.

Nature 20101202

Catalytic asymmetric synthesis of both enantiomers of 4‑substituted 1,4-dihydropyridines with the use of bifunctional thiourea-ammonium salts bearing different counterions.

Molecules (Basel, Switzerland) 20101115

Synthesis of new tripodal Hantzsch 1,4-dihydropyridines under solvent-free condition and their conversion to the corresponding tripodal pyridines.

Molecular diversity 20101101

Brain-specific delivery of naproxen using different carrier systems.

Archiv der Pharmazie 20101101

Exceptional thermal stability in a supramolecular organic framework: porosity and gas storage.

Journal of the American Chemical Society 20101020

Insertion of pyridine into the calcium allyl bond: regioselective 1,4-dihydropyridine formation and C-H bond activation.

Angewandte Chemie (International ed. in English) 20101011

PAC1hop receptor activation facilitates catecholamine secretion selectively through 2-APB-sensitive Ca(2+) channels in PC12 cells.

Cellular signalling 20101001

Synthesis of a library of 5,6-unsubstituted 1,4-dihydropyridines based on a one-pot 4CR/elimination process and their application to the generation of structurally diverse fused nitrogen heterocycles.

Journal of combinatorial chemistry 20100913

Synthesis and biological evaluation of novel hybrid chalcone derivatives as vasorelaxant agents.

European journal of medicinal chemistry 20100901

Flutamide inhibits nifedipine- and interleukin-1 beta-induced collagen overproduction in gingival fibroblasts.

Journal of periodontal research 20100801

Novel structure-activity relationships and selectivity profiling of cage dimeric 1,4-dihydropyridines as multidrug resistance (MDR) modulators.

Bioorganic & medicinal chemistry 20100715

Facile and efficient aromatization of 1,4-dihydropyridines with M(NO3)2.XH2O, TNCB, TBAP and HMTAI and preparation of deuterium labeled dehydronifedipine from nifedipine-d3.

Bioorganic & medicinal chemistry letters 20100615

Dihydropyridine-insensitive calcium currents contribute to function of small cerebral arteries.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20100601

Design and synthesis of 1,4-dihydropyridine derivatives as BACE-1 inhibitors.

European journal of medicinal chemistry 20100601

Delayed diagnosis of primary hyperaldosteronism.

BMJ (Clinical research ed.) 20100525

Antagonism of 4-substituted 1,4-dihydropyridine-3,5-dicarboxylates toward voltage-dependent L-type Ca2+ channels Ca V 1.3 and Ca V 1.2.

Bioorganic & medicinal chemistry 20100501

L-type calcium channel blockers and Parkinson disease in Denmark.

Annals of neurology 20100501

A region of N-type Ca(2+) channel critical for blockade by the dihydropyridine amlodipine.

European journal of pharmacology 20100425

Design, multicomponent synthesis, and bioactivities of novel neonicotinoid analogues with 1,4-dihydropyridine scaffold.

Journal of agricultural and food chemistry 20100310

Interaction of (benzylidene-hydrazono)-1,4-dihydropyridines with beta-amyloid, acetylcholine, and butyrylcholine esterases.

Bioorganic & medicinal chemistry 20100301

Synthesis and biological evaluation of N-aryl-1,4-dihydropyridines as novel antidyslipidemic and antioxidant agents.

European journal of medicinal chemistry 20100201

Synthesis and biological activity of the calcium modulator (R) and (S)-3-methyl 5-pentyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.

Bioorganic & medicinal chemistry letters 20100201

Clevidipine for severe hypertension in acute heart failure: a VELOCITY trial analysis.

Congestive heart failure (Greenwich, Conn.) 20100101

Betablockers in combination with other antihypertensives.

Indian heart journal 20100101

L-proline-catalyzed synthesis of highly functionalized multisubstituted 1,4-dihydropyridines.

Organic & biomolecular chemistry 20091207

Synthesis, coordination chemistry and bonding of strong N-donor ligands incorporating the 1H-pyridin-(2E)-ylidene (PYE) motif.

Chemistry (Weinheim an der Bergstrasse, Germany) 20091026

Prediction of photosensitivity of 1,4-dihydropyridine antihypertensives by quantitative structure-property relationship.

Talanta 20091015

Aryl bridged 1-hydroxypyridin-2-one: effect of the bridge on the Eu(III) sensitization process.

Inorganic chemistry 20091005

Effects of 5-acetyl(carbamoyl)-6-methylsulfanyl-1,4-dihydropyridine-5-carbonitriles on rat liver mitochondrial function.

Toxicology in vitro : an international journal published in association with BIBRA 20091001

[H2O2 oxidation of 1,4-dihydropyridines over Mg2+ ion exchanged clinoptilolite and solventless solid state acid decomposition of ester to 3,5-pyridinedicarboxylic acid].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20091001

Suppression of formalin-induced nociception by cilnidipine, a voltage-dependent calcium channel blocker.

Biological & pharmaceutical bulletin 20091001

Exploring catalyst and solvent effects in the multicomponent synthesis of pyridine-3,5-dicarbonitriles.

The Journal of organic chemistry 20090918

Oxidative aromatization of 1,4-dihydropyridines and pyrazolines using HbA-H(2)O(2): An efficient biomimetic catalyst system providing metabolites of drug candidates.

Bioorganic & medicinal chemistry letters 20090801

Structural model for dihydropyridine binding to L-type calcium channels.

The Journal of biological chemistry 20090710

Dihydropyridine- and voltage-sensitive Ca2+ entry in human parathyroid cells.

Experimental physiology 20090701

Five different profiles of dihydropyridines in blocking T-type Ca(2+) channel subtypes (Ca(v)3.1 (alpha(1G)), Ca(v)3.2 (alpha(1H)), and Ca(v)3.3 (alpha(1I))) expressed in Xenopus oocytes.

European journal of pharmacology 20090624

Assessment and use of two silicon carbide multi-well plates for library synthesis and proteolytic digests using microwave heating.

Organic & biomolecular chemistry 20090607

Evidence for regulation of mitochondrial function by the L-type Ca2+ channel in ventricular myocytes.

Journal of molecular and cellular cardiology 20090601

Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease.

Journal of medicinal chemistry 20090514

Dihydropyridine C-glycoconjugates by organocatalytic Hantzsch cyclocondensation. Stereoselective synthesis of alpha-threofuranose C-nucleoside enantiomers.

Organic & biomolecular chemistry 20090507

Expression of voltage-activated calcium channels in the early zebrafish embryo.

Zygote (Cambridge, England) 20090501

Genetic polymorphisms of L-type calcium channel alpha1C and alpha1D subunit genes are associated with sensitivity to the antihypertensive effects of L-type dihydropyridine calcium-channel blockers.

Circulation journal : official journal of the Japanese Circulation Society 20090401

Isolation and pharmacological characterization of fatty acids from saw palmetto extract.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20090401

Synthesis and docking studies of new 1,4-dihydropyridines containing 4-(5)-Chloro-2-ethyl-5-(4)-imidazolyl substituent as novel calcium channel agonist.

Archives of pharmacal research 20090401

[Perspectives of inhibition of multidrug resistance during cancer chemotherapy, in vitro and in vivo experiments].

Orvosi hetilap 20090329

1-Malonyl-1,4-dihydropyridine as a novel carrier for specific delivery of drugs to the brain.

Bioorganic & medicinal chemistry 20090215

Expression and 1,4-dihydropyridine-binding properties of brain L-type calcium channel isoforms.

Molecular pharmacology 20090201

Rationale, study design and implementation of the COLM study: the combination of OLMesartan and calcium channel blocker or diuretic in high-risk elderly hypertensive patients.

Hypertension research : official journal of the Japanese Society of Hypertension 20090201

Differential sensitivities of CaV1.2 IIS5-S6 mutants to 1,4-dihydropyridine analogs.

European journal of pharmacology 20090114

Dihydropyridine inhibition of the glycine receptor: subunit selectivity and a molecular determinant of inhibition.

Neuropharmacology 20090101

How to extend the use of grid-based interaction energy maps from chemistry to biotopics.

ChemMedChem 20090101

The regio- and stereoselective synthesis of trans-2,3-dihydropyridine N-oxides and piperidines.

Angewandte Chemie (International ed. in English) 20090101

Bis-enaminone based parallel solution-phase synthesis of 1,4-dihydropyridine derivatives.

Journal of combinatorial chemistry 20090101

Modulation of cellular defense processes in human lymphocytes in vitro by a 1,4-dihydropyridine derivative.

Mutation research 20090101

Synthesis, characterization and anticonvulsant activity evaluation of some 1,4-dihydropyridines and 3,5-(substituted)oxycarbonyl-1,4-dihydro-2,6-dimethyl-N-[2-(4-sulfamoylphenylamino)-acetyl]-4-(substituted)pyridines.

Acta poloniae pharmaceutica 20090101

Spermatogenesis following discontinuation of calcium channel blocker amlodipine in rats.

Journal of Ayub Medical College, Abbottabad : JAMC 20090101

Sustainable synthetic methods: domino construction of dihydropyridin-4-ones and beta-amino esters in aqueous ethanol.

Organic letters 20081120

Calcium-channel blockers reduce the antiplatelet effect of clopidogrel.

Journal of the American College of Cardiology 20081104

Structure-activity relationships of 1,4-dihydropyridines that act as enhancers of the vanilloid receptor 1 (TRPV1).

Bioorganic & medicinal chemistry 20081015

A highly efficient biomimetic aromatization of Hantzsch-1,4-dihydropyridines with t-butylhydroperoxide, catalysed by iron(III) phthalocyanine chloride.

Bioorganic & medicinal chemistry 20081015

The structure-activity relationship study on 2-, 5-, and 6-position of the water soluble 1,4-dihydropyridine derivatives blocking N-type calcium channels.

Bioorganic & medicinal chemistry letters 20080901

One-pot synthesis of highly functionalized pyridines via a rhodium carbenoid induced ring expansion of isoxazoles.

Journal of the American Chemical Society 20080709

The solvent-free synthesis of 1,4-dihydropyridines under ultrasound irradiation without catalyst.

Ultrasonics sonochemistry 20080701

Effective management of hypertension with dihydropyridine calcium channel blocker-based combination therapy in patients at high cardiovascular risk.

International journal of clinical practice 20080501

A genetic screen for dihydropyridine (DHP)-resistant worms reveals new residues required for DHP-blockage of mammalian calcium channels.

PLoS genetics 20080501

Evaluation of anticancer effects of newly synthesized dihydropyridine derivatives in comparison to verapamil and doxorubicin on T47D parental and resistant cell lines in vitro.

Cell biology and toxicology 20080401

[Interaction of 1,4-dihydropyridines with ion channels].

Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20080401

Imidazo[2,1-b]thiazole system: a scaffold endowing dihydropyridines with selective cardiodepressant activity.

Journal of medicinal chemistry 20080327

Synthesis of unsymmetrical substituted 1,4-dihydropyridines through thermal and microwave assisted [4+2] cycloadditions of 1-azadienes and allenic esters.

The Journal of organic chemistry 20080321

Synthesis of 6-amino-1,4-dihydropyridines that prevent calcium overload and neuronal death.

European journal of medicinal chemistry 20080301

A number of marketed dihydropyridine calcium channel blockers have mineralocorticoid receptor antagonist activity.

Hypertension (Dallas, Tex. : 1979) 20080301

Structure-activity relationships of receptor binding of 1,4-dihydropyridine derivatives.

Biological & pharmaceutical bulletin 20080301

Sulfonic acid functionalized silica: an efficient heterogeneous catalyst for a three-component synthesis of 1,4-dihydropyridines under solvent-free conditions.

Chemical & pharmaceutical bulletin 20080301

Ultrasound-assisted photochemical oxidation of unsymmetrically substituted 1,4-dihydropyridines.

Ultrasonics sonochemistry 20080201

Inclusion of patients who overdose with dihydropyridine calcium channel blockers would potentially increase clinical utility of hyperglycemia.

Critical care medicine 20080201

Relationship between lipophilicities of 1,4-dihydropyridine derivatives and pharmacokinetic interaction strengths with grapefruit juice.

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080101

Analysis of dihydropyridine calcium channel blockers using negative ion photoionization mass spectrometry.

Journal of chromatographic science 20080101

Microwave-assisted combinatorial synthesis of hexa-substituted 1,4-dihydropyridines scaffolds using one-pot two-step multicomponent reaction followed by a S-alkylation.

Journal of combinatorial chemistry 20080101

L-type Ca2+ channel function is linked to dystrophin expression in mammalian muscle.

PloS one 20080101

Hantzsch synthesis of 2,6-dimethyl-3,5-dimethoxycarbonyl-4-(o-methoxyphenyl)-1,4-dihydropyridine; a novel cyclisation leading to an unusual formation of 1-amino-2-methoxy-carbonyl-3,5-bis(o-methoxyphenyl)-4-oxa-cyclohexan-1-ene.

Molecules (Basel, Switzerland) 20071126

[Hypertension as a source of cognitive regression, or dementia].

Nederlands tijdschrift voor geneeskunde 20071103

9-phenyl-10-methylacridinium: a highly efficient and reusable organocatalyst for mild aromatization of 1,4-dihydropyridines by molecular oxygen.

The Journal of organic chemistry 20071026

Synthesis, QSAR and calcium channel antagonist activity of new 1,4-dihydropyridine derivatives containing 1-methyl-4,5-dichloroimidazolyl substituents.

Archiv der Pharmazie 20071001

Domino reaction of 3-(2-formylphenoxy)propenoates and amines: a novel synthesis of 1,4-dihydropyridines from salicaldehydes, ethyl propiolate, and amines.

The Journal of organic chemistry 20070928

Are differences in calcium antagonists relevant across all stages of nephropathy or only proteinuric nephropathy?

Current opinion in nephrology and hypertension 20070901

Autocrine activation of ion currents in the two-cell mouse embryo.

Experimental cell research 20070801

Structure-activity relationship of 1,4-dihydropyridines as potentiators of the cystic fibrosis transmembrane conductance regulator chloride channel.

Molecular pharmacology 20070701

Calcicludine binding to the outer pore of L-type calcium channels is allosterically coupled to dihydropyridine binding.

Biochemistry 20070626

Oxidation of C4-hydroxyphenyl 1,4-dihydropyridines in dimethylsulfoxide and its reactivity towards alkylperoxyl radicals in aqueous medium.

Bioorganic & medicinal chemistry 20070615

Oxidative aromatization of Hantzsch 1,4-dihydropyridines in the presence of mixed-addenda vanadomolybdophosphate heteropolyacid, H6PMo9V3O40.

Bioorganic & medicinal chemistry letters 20070615

Analyses by GC-MS and GC-MS-MS of the Hantzsch synthesis products using hydroxy- and methoxy-aromatic aldehydes.

Journal of pharmaceutical and biomedical analysis 20070509

The effect of ionizing radiation of 1,4-dihydropyridine derivatives in the solid state.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070501

One-step synthesis of heterocyclic privileged medicinal scaffolds by a multicomponent reaction of malononitrile with aldehydes and thiols.

The Journal of organic chemistry 20070427

G1 cell cycle arrest by amlodipine, a dihydropyridine Ca2+ channel blocker, in human epidermoid carcinoma A431 cells.

Biochemical pharmacology 20070401

N-methyl-(R)-3-(tert-butyl)-sulfinyl-1,4-dihydropyridine: a novel NADH model compound.

Molecules (Basel, Switzerland) 20070312

A convenient and efficient protocol for oxidative aromatization of Hantzsch 1,4-dihydropyridines using benzyltriphenylphosphonium peroxymonosulfate under almost neutral reaction conditions.

Bioorganic & medicinal chemistry letters 20070215

Maturation of rat cerebellar Purkinje cells reveals an atypical Ca2+ channel current that is inhibited by omega-agatoxin IVA and the dihydropyridine (-)-(S)-Bay K8644.

The Journal of physiology 20070201

Distinct effects of atypical 1,4-dihydropyridines on 1-methyl-4-phenylpyridinium-induced toxicity.

Cell biochemistry and function 20070101

Photophysics and photochemical studies of 1,4-dihydropyridine derivatives.

Photochemistry and photobiology 20070101

Recent advances in alpha1-adrenoreceptor antagonists as pharmacological tools and therapeutic agents.

Current topics in medicinal chemistry 20070101

Calcium channels blockers and progression of kidney disease.

Renal failure 20070101

[Hypotensive efficacy and tolerability of combination of dihydropyridine and non-dihydropyridine calcium antagonists in the treatment of patients with arterial hypertension].

Kardiologiia 20070101

Novel multipotent tacrine-dihydropyridine hybrids with improved acetylcholinesterase inhibitory and neuroprotective activities as potential drugs for the treatment of Alzheimer's disease.

Journal of medicinal chemistry 20061228

Regulation of the homologous two-component systems KvgAS and KvhAS in Klebsiella pneumoniae CG43.

Journal of biochemistry 20061101

The actions of azelnidipine, a dihydropyridine-derivative Ca antagonist, on voltage-dependent Ba2+ currents in guinea-pig vascular smooth muscle.

British journal of pharmacology 20061101

Physicochemical characteristics of novel P-glycoprotein inhibitors of the cage dimeric 1,4-dihydropyridine type.

Medicinal chemistry (Shariqah (United Arab Emirates)) 20061101

Synthesis of a naphthyridone p38 MAP kinase inhibitor.

The Journal of organic chemistry 20061027

Rhes expression in pancreatic beta-cells is regulated by efaroxan in a calcium-dependent process.

Biochemical and biophysical research communications 20061020

Randomized study of angiotensin II type 1 receptor blocker vs dihydropiridine calcium antagonist for the treatment of paroxysmal atrial fibrillation in patients with hypertension.

Circulation journal : official journal of the Japanese Circulation Society 20061001

Switch between charge transfer and local excited states in 4-aminophenyl-substituted Hantzsch 1,4-dihydropyridine induced by pH change and transition metal ions.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20061001

Nitro radical anion formation from nitrofuryl substituted 1,4-dihydropyridine derivatives in mixed and non-aqueous media.

Bioelectrochemistry (Amsterdam, Netherlands) 20060901

Cancer cell permeability-glycoprotein as a target of MDR reverters: possible role of novel dihydropyridine derivatives.

Current drug targets 20060801

QSAR study of 1,4-dihydropyridine calcium channel antagonists based on gene expression programming.

Bioorganic & medicinal chemistry 20060715

Fused 1,4-dihydropyridines as potential calcium modulatory compounds.

Mini reviews in medicinal chemistry 20060701

Design, synthesis, and calcium channel antagonist activity of new 1,4-dihydropyridines containing 4-(5)-chloro-2-ethyl-5-(4)-imidazolyl substituent.

Archiv der Pharmazie 20060601

The cGMP/protein kinase G pathway contributes to dihydropyridine-sensitive calcium response and cytokine production in TH2 lymphocytes.

The Journal of biological chemistry 20060505

Biological evaluation of bishydroxymethyl-substituted cage dimeric 1,4-dihydropyridines as a novel class of p-glycoprotein modulating agents in cancer cells.

Journal of medicinal chemistry 20060504

Rapid and efficient oxidation of Hantzsch 1,4-dihydropyridines with sodium periodate catalyzed by manganese (III) Schiff base complexes.

Bioorganic & medicinal chemistry 20060415

Mild and efficient oxidation of Hantzsch 1,4-dihydropyridines with sodium periodate catalyzed by a new polystyrene-bound Mn(TPP)Cl.

Bioorganic & medicinal chemistry letters 20060401

Cocrystals of diastereoisomers of 1,4-dihydropyridine derivatives.

Acta crystallographica. Section C, Crystal structure communications 20060401

Solid phase synthesis of a redox delivery system with the aim of targeting peptides into the brain.

Organic & biomolecular chemistry 20060307

Structure-activity relationship study of 1,4-dihydropyridine derivatives blocking N-type calcium channels.

Bioorganic & medicinal chemistry letters 20060215

HPLC method for analysis of a new 1,4-dihydropyridine: application to pharmacokinetic study in rabbit.

Journal of pharmaceutical and biomedical analysis 20060213

Does the MOSES trial establish superiority of AT1-receptor blockers over dihydropyridine/calcium antagonists in secondary stroke prevention?

Stroke 20060201

Instability of calcium channel antagonists during sample preparation for LC-MS-MS analysis of serum samples.

Forensic science international 20060106

The L-type calcium channel blockers, hantzsch 1,4-dihydropyridines, are not peroxyl radical-trapping, chain-breaking antioxidants.

Chemical research in toxicology 20060101

Study of the interaction of 1,4-dihydropyridine derivatives with glucocorticoid hormone receptors from the rat liver.

Pharmacological reports : PR 20060101

Photostabilization of 1,4-dihydropyridine antihypertensives by incorporation into beta-cyclodextrin and liposomes.

Journal of nanoscience and nanotechnology 20060101

Antihypertensive 1,4-dihydropyridines as correctors of the cystic fibrosis transmembrane conductance regulator channel gating defect caused by cystic fibrosis mutations.

Molecular pharmacology 20051201

Substantial reaction between histamine and malondialdehyde: a new observation of carbonyl stress.

Neuro endocrinology letters 20051201

A 1,4-dihydropyridine derivative reduces DNA damage and stimulates DNA repair in human cells in vitro.

Mutation research 20051110

Parallel, solution phase synthesis of dihydropyridine miticides via a versatile multicomponent reaction.

Combinatorial chemistry & high throughput screening 20051101

Cerebrocrast promotes the cotransport of H+ and Cl- in rat liver mitochondria.

Mitochondrion 20051001

PHARMAC responds to Stewart Mann on dihydropyridine calcium channel antagonists.

The New Zealand medical journal 20050812

Biomimetic oxidation of Hantzsch 1,4-dihydropyridines with tetra-n-butylammonium periodate catalyzed by tetraphenylporphyrinatomanganese(III) chloride [Mn(TPP)Cl].

Bioorganic & medicinal chemistry letters 20050701

1,4-Dihydropyridine derivatives as calcium channel modulators: the role of 3-methoxy-flavone moiety.

Bioorganic & medicinal chemistry 20050516

An approach for measuring in vivo cerebral redox states using the oxidative conversion of dihydropyridine to pyridinium ion and the metabolic trapping principle.

Free radical biology & medicine 20050501

Effect of compression on interaction between 1,4-dihydropyridine compounds and lactose monohydrate.

Chemical & pharmaceutical bulletin 20050501

The relationship between magnitude of proteinuria reduction and risk of end-stage renal disease: results of the African American study of kidney disease and hypertension.

Archives of internal medicine 20050425

BENEDICT in the treatment of hypertension.

Current hypertension reports 20050401

Emergence of a R-type Ca2+ channel (CaV 2.3) contributes to cerebral artery constriction after subarachnoid hemorrhage.

Circulation research 20050304

Intraglomerular inhibition: signaling mechanisms of an olfactory microcircuit.

Nature neuroscience 20050301

Hantzsch 1,4-dihydropyridines containing a diazen-1-ium-1,2-diolate nitric oxide donor moiety to study calcium channel antagonist structure-activity relationships and nitric oxide release.

Bioorganic & medicinal chemistry 20050301

Substituted thiazolamide coupled to a redox delivery system: a new gamma-secretase inhibitor with enhanced pharmacokinetic profile.

Organic & biomolecular chemistry 20050221

Applying pattern recognition methods and structure property correlations to determine drug carrier potential of nicotinic acid and analogize to dihydropyridine.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20050101

Case studies in hypertension. Dihydropyridine/nondihydropyridine calcium channel blocker combination therapy.

Journal of clinical hypertension (Greenwich, Conn.) 20050101

[Toxicological analysis of selected 1,4-dihydropyridine calcium channel blockers in the diagnosis of intoxications].

Archiwum medycyny sadowej i kryminologii 20050101

QSAR and classification study of 1,4-dihydropyridine calcium channel antagonists based on least squares support vector machines.

Molecular pharmaceutics 20050101

Improvement of the chromatographic separation of several 1,4-dihydropyridines calcium channel antagonist drugs by experimental design.

Journal of chromatographic science 20050101

Opposite effects of a single IIIS5 mutation on phenylalkylamine and dihydropyridine interaction with L-type Ca2+ channels.

The Journal of biological chemistry 20041231

Isosteric N-arylpiperazine replacements in a series of dihydropyridine NPY1 receptor antagonists.

Bioorganic & medicinal chemistry letters 20041220

Selective glucocorticoid receptor nonsteroidal ligands completely antagonize the dexamethasone mediated induction of enzymes involved in gluconeogenesis and glutamine metabolism.

The Journal of steroid biochemistry and molecular biology 20041201

Drug treatment of essential hypertension: the case for initial combination therapy.

International journal of clinical practice 20041001

Dioleoyl phosphatidylethanolamine and PEG-lipid conjugates modify DNA delivery mediated by 1,4-dihydropyridine amphiphiles.

Journal of controlled release : official journal of the Controlled Release Society 20040914

Application of ab initio theory to QSAR study of 1,4-dihydropyridine-based calcium channel blockers using GA-MLR and PC-GA-ANN procedures.

Journal of computational chemistry 20040901

Dihydropyridine calcium channel blockers: basic pharmacological similarities but fundamental therapeutic differences.

Journal of hypertension 20040901

Synthesis and biological evaluation of 1,4-dihydropyridine calcium channel modulators having a diazen-1-ium-1,2-diolate nitric oxide donor moiety for the potential treatment of congestive heart failure.

Bioorganic & medicinal chemistry 20040715

1,4-dihydropyridines: reactivity of nitrosoaryl and nitroaryl derivatives with alkylperoxyl radicals and ABTS radical cation.

Free radical research 20040701

Proliferation of cultured human gingival fibroblasts caused by isradipine, a dihydropyridine-derivative calcium antagonist.

European journal of medical research 20040630

Screening for dihydropyridine calcium channel blockers in plasma by automated solid-phase extraction and liquid chromatography/tandem mass spectrometry.

Journal of mass spectrometry : JMS 20040601

Marrubenol interacts with the phenylalkylamine binding site of the L-type calcium channel.

European journal of pharmacology 20040525

Structural effects on the reactivity 1,4-dihydropyridines with alkylperoxyl radicals and ABTS radical cation.

Bioorganic & medicinal chemistry 20040501

Acute and sustained effects of dihydropyridine-type calcium channel antagonists on oxidative stress in systemic sclerosis.

The American journal of medicine 20040501

Metabolic formation of DHP-derived DNA adducts from a representative otonecine type pyrrolizidine alkaloid clivorine and the extract of Ligularia hodgsonnii hook.

Chemical research in toxicology 20040501

Molecular mechanisms of vasoselectivity of the 1,4-dihydropyridine lercanidipine.

British journal of pharmacology 20040501

HPLC enantiomer separation of a chiral 1,4-dihydropyridine monocarboxylic acid.

Journal of pharmaceutical and biomedical analysis 20040416

Polyphenolic antioxidants mimic the effects of 1,4-dihydropyridines on neurotensin receptor function in PC3 cells.

The Journal of pharmacology and experimental therapeutics 20040401

Cloning of the Cav 1.3 (alpha1D) L-type Ca2+ channel from mouse and its expression in the liver.

International journal of molecular medicine 20040401

Dihydropiridines mechanism of action in striatal isolated nerve endings: comparison with omega-agatoxin IVA.

Neurochemical research 20040401

Effects of immediate versus delayed antihypertensive therapy on outcome in the Systolic Hypertension in Europe Trial.

Journal of hypertension 20040401

Synthetic strategy toward skeletal diversity via solid-supported, otherwise unstable reactive intermediates.

Angewandte Chemie (International ed. in English) 20040319

Disruption of intestinal motility by a calcium channel-stimulating autoantibody in type 1 diabetes.

Gastroenterology 20040301

Dihydropyridine neuropeptide Y Y1 receptor antagonists 2. bioisosteric urea replacements.

Bioorganic & medicinal chemistry 20040115

Inhibition of type A GABA receptors by L-type calcium channel blockers.

Neuroscience 20040101

Effect of new and known 1,4-dihydropyridine derivatives on blood glucose levels in normal and streptozotocin-induced diabetic rats.

Cell biochemistry and function 20040101

[Radiation modulating properties of derivates of 1,4-dihydropyridine and 1,2,3,4,5,6,7,8,9,10-decahydroacridine-1,8 dione].

Radiatsionnaia biologiia, radioecologiia 20040101

Quantitative structure-activity relationship studies on some series of calcium channel blockers.

Molecular diversity 20040101

Evaluation of a simple carrier molecule to enhance drug penetration of dermal layers by utilizing multivariate methods, structure property correlations, and continuous system modeling.

Physiological chemistry and physics and medical NMR 20040101

Modified cardiovascular L-type channels in mice lacking the voltage-dependent Ca2+ channel beta3 subunit.

The Journal of biological chemistry 20031031

Glucose-lowering in a db/db mouse model by dihydropyridine diacid glycogen phosphorylase inhibitors.

Bioorganic & medicinal chemistry letters 20031020

Synthesis and anticonvulsant activity of novel 1-substituted-1,2-dihydro-pyridazine-3,6-diones.

Biological & pharmaceutical bulletin 20031001

Clinical and economic consequences of reference pricing for dihydropyridine calcium channel blockers.

Clinical pharmacology and therapeutics 20031001

Synthesis, in vitro and in vivo evaluation of a delivery system for targeting anticancer drugs to the brain.

Archiv der Pharmazie 20031001

Modulation of manganese currents by 1, 4-dihydropyridines, isoproterenol and forskolin in rabbit ventricular cells.

Pflugers Archiv : European journal of physiology 20030901

Hypothyroidism does not affect the dihydropyridine sensitivity of precontracted murine uterus.

Canadian journal of physiology and pharmacology 20030901

L-type calcium channel activation up-regulates the mRNAs for two different sodium channel alpha subunits (Nav1.2 and Nav1.3) in rat pituitary GH3 cells.

Brain research. Molecular brain research 20030819

DHP-insensitive L-type-like Ca channel of ascidian acquires sensitivity to DHP with single amino acid change in domain III P-region.

FEBS letters 20030814

Key roles of Phe1112 and Ser1115 in the pore-forming IIIS5-S6 linker of L-type Ca2+ channel alpha1C subunit (CaV 1.2) in binding of dihydropyridines and action of Ca2+ channel agonists.

Molecular pharmacology 20030801

Cav1.4alpha1 subunits can form slowly inactivating dihydropyridine-sensitive L-type Ca2+ channels lacking Ca2+-dependent inactivation.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20030709

[125I]A-312110, a novel high-affinity 1,4-dihydropyridine ATP-sensitive K+ channel opener: characterization and pharmacology of binding.

Molecular pharmacology 20030701

Enantiomeric separation by HPLC of 1,4-dihydropyridines with vancomycin as chiral selector.

Chirality 20030601

1,4-Dihydropyridines as calcium channel ligands and privileged structures.

Cellular and molecular neurobiology 20030601

The L-type Ca2+-channel subunits alpha1C and beta2 are not downregulated in atrial myocardium of patients with chronic atrial fibrillation.

Journal of molecular and cellular cardiology 20030501

New carrier for specific delivery of drugs to the brain.

Bioorganic & medicinal chemistry 20030417

Ca v 1.3 is preferentially coupled to glucose-stimulated insulin secretion in the pancreatic beta-cell line INS-1.

The Journal of pharmacology and experimental therapeutics 20030401

Inhibition of cAMP signalling cascade-mediated Ca2+ influx by a prothoracicostatic peptide (Mas-MIP I) via dihydropyridine-sensitive Ca2+ channels in the prothoracic glands of the silkworm, Bombyx mori.

Insect biochemistry and molecular biology 20030201

Location of ryanodine and dihydropyridine receptors in frog myocardium.

Biophysical journal 20030201

Functional interaction of auxiliary subunits and synaptic proteins with Ca(v)1.3 may impart hair cell Ca2+ current properties.

Journal of neurophysiology 20030201

Reactivity of 1,4-dihydropyridines toward alkyl, alkylperoxyl radicals, and ABTS radical cation.

Chemical research in toxicology 20030201

Modulation of L-type Ca2+ channels in neonatal rat heart by a novel Ca2+ channel agonist.

Canadian journal of physiology and pharmacology 20030201

Pharmacological characterization of a 1,4-dihydropyridine analogue, 9-(3,4-dichlorophenyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydro-1,8(2H,5H)-acridinedione (A-184209) as a novelK(ATP) channel inhibitor.

British journal of pharmacology 20030101

Comparison between neural networks (NN) and principal component analysis (PCA): structure activity relationships of 1,4-dihydropyridine calcium channel antagonists (nifedipine analogues).

Journal of chemical information and computer sciences 20030101

Atheroprotective effects of long-acting dihydropyridine-type calcium channel blockers: evidence from clinical trials and basic scientific research.

Cerebrovascular diseases (Basel, Switzerland) 20030101

Does QTc interval predict the response to beta-blockers and calcium channel blockers in hypertensives?

Heart disease (Hagerstown, Md.) 20030101

The ascidian dihydropyridine-resistant calcium channel as the prototype of chordate L-type calcium channel.

Neuro-Signals 20030101

Photo- and radiostability of some 1,4-dihydropyridine derivatives in the solid state.

Acta poloniae pharmaceutica 20030101

Incidence of pedal edema formation with dihydropyridine calcium channel blockers: issues and practical significance.

Journal of clinical hypertension (Greenwich, Conn.) 20030101

Risk of myocardial infarction with combination antihypertensive regimens including a dihydropyridine calcium channel blocker in hypertensive diabetics.

Journal of managed care pharmacy : JMCP 20030101

Decoration of dihydropyrimidine and dihydropyridine scaffolds with sugars via Biginelli and Hantzsch multicomponent reactions: an efficient entry to a collection of artificial nucleosides.

Molecular diversity 20030101

MRS study of the interaction of dihydropyridines with lipid molecules in phosphatidylcholine vesicles.

Physiological chemistry and physics and medical NMR 20030101

[Innovative molecular transformation using optically active alpha-amino acids].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20021101

Passive transfer of Lambert-Eaton syndrome to mice induces dihydropyridine sensitivity of neuromuscular transmission.

The Journal of physiology 20020901

Heart rate in hypertensive patients treated with ACE inhibitors and long-acting dihydropyridine calcium antagonists.

Journal of cardiovascular pharmacology 20020801

Effects of UV and visible light on cyanobacteria at the cellular level.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20020801

Face-selective addition to a cation-pi complex of a pyridinium salt: synthesis of chiral 1,4-dihydropyridines.

Journal of the American Chemical Society 20020717

Extracellular and intracellular factors influencing gene transfection mediated by 1,4-dihydropyridine amphiphiles.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20020601

Angiotensin converting enzyme inhibition and dihydropyridine calcium channel blockade in the treatment of left ventricular hypertrophy in arterial hypertension.

Minerva cardioangiologica 20020601

A novel water-soluble Hantzsch 1,4-dihydropyridine compound that functions in biological processes through NADH regeneration.

The Journal of organic chemistry 20020517

Productive trapping of NAD-type radicals. Non-biomimetic reduction of pyridinium salts.

Chemical communications (Cambridge, England) 20020421

Enhanced vascular effects of the Ca(2+) channel agonist Bay K 8644 in pregnant rabbits.

American journal of physiology. Regulatory, integrative and comparative physiology 20020401

A spectroscopic investigation of hydrogen bond patterns in crystalline and amorphous phases in dihydropyridine calcium channel blockers.

Pharmaceutical research 20020401

The effect of temperature on hydrogen bonding in crystalline and amorphous phases in dihydropyrine calcium channel blockers.

Pharmaceutical research 20020401

Impact of an ACE inhibitor and calcium antagonist on microalbuminuria and lipid subfractions in type 2 diabetes: a randomised, multi-centre pilot study.

Journal of human hypertension 20020301

The effect of ionizing radiation on some derivatives of 1,4-dihydropyridine in the solid state.

International journal of pharmaceutics 20020221

Calcium involvement in the luminescence control of three ophiuroid species (Echinodermata).

Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020201

Effect of acyl chain length and branching on the enantioselectivity of Candida rugosa lipase in the kinetic resolution of 4-(2-difluoromethoxyphenyl)-substituted 1,4-dihydropyridine 3,5-diesters.

The Journal of organic chemistry 20020125

[Clastogenicity of ethyl methanesulfonate and dimethyl terephthalate in the micronucleus test and ways for its modification].

TSitologiia i genetika 20020101

Comparison of losartan with ACE inhibitors and dihydropyridine calcium channel antagonists: a pilot study of prescription-event monitoring in Japan.

Drug safety 20020101

Treatment of hypertensive retinopathy.

Survey of ophthalmology 20020101

Neuroprotective effect of treatment with calcium antagonists on hypertensive retina.

Clinical and experimental hypertension (New York, N.Y. : 1993) 20020101

Gas chromatography/mass spectrometric study of non-commercial C-4-substituted 1,4-dihydropyridines and their oxidized derivatives.

Rapid communications in mass spectrometry : RCM 20020101

A prokaryotic voltage-gated sodium channel.

Science (New York, N.Y.) 20011214

A component of excitation-contraction coupling triggered in the absence of the T671-L690 and L720-Q765 regions of the II-III loop of the dihydropyridine receptor alpha(1s) pore subunit.

Biophysical journal 20011201

Dihydropyridine calcium-channel blockers for antihypertensive treatment in older patients--evidence from the Systolic Hypertension in Europe Trial.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20011201

Independent modulation of L-type Ca2+ channel in guinea pig ventricular cells by nitrendipine and isoproterenol.

Japanese heart journal 20011101

Torquoselectivity induced by lone-pair conjugation in the electrocyclic reactions of 1-azapolyenes.

The Journal of organic chemistry 20011005

Dihydropyridine calcium channel blockers and peripheral side effects.

Journal of human hypertension 20011001

Role of dihydropyridine-sensitive calcium channels in the regulation of norepinephrine release in hypertension.

Journal of cardiovascular pharmacology 20011001

Mechanism of action of angiotensin II in human isolated subcutaneous resistance arteries.

British journal of pharmacology 20010901

Laragh's lessons in pathophysiology and clinical pearls for treating hypertension.

American journal of hypertension 20010901

Pilot study to evaluate a water displacement technique to compare effects of diuretics and ACE inhibitors to alleviate lower extremity edema due to dihydropyridine calcium antagonists.

American journal of hypertension 20010901

3-Methyl 5-isopropyl 2-methoxyiminomethyl-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.

Acta crystallographica. Section C, Crystal structure communications 20010901

Neuronal Ca(V)1.3alpha(1) L-type channels activate at relatively hyperpolarized membrane potentials and are incompletely inhibited by dihydropyridines.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20010815

Treatment advances for cocaine-induced ischemic stroke: focus on dihydropyridine-class calcium channel antagonists.

The American journal of psychiatry 20010801

Stereoselective trans- and cis-dihydroxylations of 2H-pyranyl and dihydropyridinyl heterocycles synthesized from formal [3 + 3]-cycloaddition reactions of alpha,beta-unsaturated iminium ions with 1,3-dicarbonyl equivalents.

Organic letters 20010712

Protein kinase C-mediated calcium entry dependent upon dihydropyridine sensitive channels: a T cell receptor-coupled signaling pathway involved in IL-4 synthesis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010701

Functional expression and characterization of a voltage-gated CaV1.3 (alpha1D) calcium channel subunit from an insulin-secreting cell line.

Molecular endocrinology (Baltimore, Md.) 20010701

Searching for balanced hybrid NO-donor 1,4-dihydropyridines with basic properties.

Pharmaceutical research 20010701

Influence of treatment with Ca(2+) antagonists on cerebral vasculature of spontaneously hypertensive rats.

Mechanisms of ageing and development 20010601

Fundamental Ca2+ signaling mechanisms in mouse dendritic cells: CRAC is the major Ca2+ entry pathway.

Journal of immunology (Baltimore, Md. : 1950) 20010515

Nifedipine-activated Ca(2+) permeability in newborn rat cortical collecting duct cells in primary culture.

American journal of physiology. Cell physiology 20010501

Ca(2+) entry into primary cultured pig coronary smooth muscle cells after previous store depletion by repetitive P2Y purinoceptor stimulation.

Cell calcium 20010501

Inhibition of ATP-induced surfactant exocytosis by dihydropyridine (DHP) derivatives: a non-stereospecific, photoactivated effect and independent of L-type Ca2+ channels.

Biochemical pharmacology 20010501

Comparative effects of selective T- and L-type calcium channel blockers in the remnant kidney model.

Hypertension (Dallas, Tex. : 1979) 20010501

Mechanism of dihydropyridine interaction with critical binding residues of L-type Ca2+ channel alpha 1 subunits.

The Journal of biological chemistry 20010420

Contribution of the plasmalemma to Ca2+ homeostasis in hair cells.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20010415

Photoreaction of 2-halo-N-pyridinylbenzamide: intramolecular cyclization mechanism of phenyl radical assisted with n-complexation of chlorine radical.

The Journal of organic chemistry 20010406

Gadolinium prevents stretch-mediated contractile dysfunction in isolated papillary muscles.

American journal of physiology. Heart and circulatory physiology 20010301

Activation of purified cardiac ryanodine receptors by dihydropyridine agonists.

American journal of physiology. Heart and circulatory physiology 20010301

Comparative study on the vasorelaxant effects of three harmala alkaloids in vitro.

Japanese journal of pharmacology 20010301

Chronic nicotine alters NO signaling of Ca(2+) channels in cerebral arterioles.

Circulation research 20010216

Biophysical properties, pharmacology, and modulation of human, neuronal L-type (alpha(1D), Ca(V)1.3) voltage-dependent calcium currents.

Journal of neurophysiology 20010201

Pharmacologic management of atrial fibrillation: current therapeutic strategies.

American heart journal 20010201

Abnormality of calcium channel inhibitor released from fetal membranes in preterm labor.

American journal of obstetrics and gynecology 20010201

Studies on agents with mixed NO-dependent and calcium channel antagonistic vasodilating activities.

Pharmaceutical research 20010201

Calcium channel isoforms underlying synaptic transmission at embryonic Xenopus neuromuscular junctions.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20010115

Calcium/calmodulin-dependent protein kinase type IV (CaMKIV) inhibits apoptosis induced by potassium deprivation in cerebellar granule neurons.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010101

Pranidipine, a 1,4-dihydropyridine calcium channel blocker that enhances nitric oxide-induced vascular relaxation.

Cardiovascular drug reviews 20010101

Expression of L-type calcium channels associated with postnatal development of skeletal muscle function in mouse.

Journal of muscle research and cell motility 20010101

High performance liquid chromatography of mebudipine: application to pharmacokinetic study.

Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20010101

[Effects of cardiovascular therapy on risk of the development of ischemia and myocardial infarction in the postoperative period in cancer patients with ischemic heart diseases].

Anesteziologiia i reanimatologiia 20010101

The learned symmetry concept in revealing quantitative structure-activity relationships with artificial neural networks.

SAR and QSAR in environmental research 20010101

Effects of isradipine, a dihydropyridine-class calcium channel antagonist, on D-methamphetamine-induced cognitive and physiological changes in humans.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20000501

Arterial responses in vitro and plasma digoxin immunoreactivity after losartan and enalapril treatments in experimental hypertension.

Pharmacology & toxicology 20000101

Inhibition of human cytochrome P450 enzymes by 1,4-dihydropyridine calcium antagonists: prediction of in vivo drug-drug interactions.

European journal of clinical pharmacology 20000101

Regional expression and functional characterization of the L-type Ca2+-channel in myocardium from patients with end-stage heart failure and in non-failing human hearts.

Journal of molecular and cellular cardiology 19990101

Interaction of 1,4-dihydropyridine and pyridine derivatives with adenosine receptors: selectivity for A3 receptors.

Journal of medicinal chemistry 19960719

Nifedipine. Dose-related increase in mortality in patients with coronary heart disease.

Circulation 19950901

Interaction of pinaverium (a quaternary ammonium compound) with 1,4-dihydropyridine binding sites in rat ileum smooth muscle.

British journal of pharmacology 19920201

Parathyroid hormone-stimulated cadmium accumulation in Madin-Darby canine kidney cells.

Toxicology and applied pharmacology 19910615

Endogenous opiate system and dihydropyridine-induced central regulation of sympathetic tone in rats.

European journal of pharmacology 19881206

Calcium currents in embryonic and neonatal mammalian skeletal muscle.

The Journal of general physiology 19880601

Central interactions between dihydropyridines and cholinergic systems in the control of blood pressure in rat.

Brain research 19871201

Renal effects of 1,4-dihydropyridines in animal models of hypertension and renal failure.

Journal of cardiovascular pharmacology 19870101

27790-75-6 | Pyridine, dihydro-

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