200,000+ products from a single source!
sales@angenechem.com
27591-69-1 | 9H-Fluoren-9-one, 2,7-bis[2-(diethylamino)ethoxy]-, hydrochloride (1:2)
CAS No: 27591-69-1 Catalog No: AG002U6B MDL No:MFCD00134071
Product Description
Catalog Number:
AG002U6B
Chemical Name:
9H-Fluoren-9-one, 2,7-bis[2-(diethylamino)ethoxy]-, hydrochloride (1:2)
CAS Number:
27591-69-1
Molecular Formula:
C25H36Cl2N2O3
Molecular Weight:
483.4709
MDL Number:
MFCD00134071
IUPAC Name:
2,7-bis[2-(diethylamino)ethoxy]fluoren-9-one;dihydrochloride
InChI:
InChI=1S/C25H34N2O3.2ClH/c1-5-26(6-2)13-15-29-19-9-11-21-22-12-10-20(30-16-14-27(7-3)8-4)18-24(22)25(28)23(21)17-19;;/h9-12,17-18H,5-8,13-16H2,1-4H3;2*1H
InChI Key:
BSVYJQAWONIOOU-UHFFFAOYSA-N
SMILES:
CCN(CCOc1ccc2c(c1)C(=O)c1c2ccc(c1)OCCN(CC)CC)CC.Cl.Cl
UNII:
BJ507J4LKY
Properties
Complexity:
477
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
3
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
482.21g/mol
Formal Charge:
0
Heavy Atom Count:
32
Hydrogen Bond Acceptor Count:
5
Hydrogen Bond Donor Count:
2
Isotope Atom Count:
0
Molecular Weight:
483.474g/mol
Monoisotopic Mass:
482.21g/mol
Rotatable Bond Count:
12
Topological Polar Surface Area:
42A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
| Title | Journal |
|---|---|
| SAR of α7 nicotinic receptor agonists derived from tilorone: exploration of a novel nicotinic pharmacophore. | Bioorganic & medicinal chemistry letters 20120215 |
| [The antiviral activity of diphenyl derivatives in different model systems]. | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20120101 |
| Dose-dependent IFN-stimulating and immunomodulating properties of 6H-indolo[2,3-B] quinoxaline derivatives. | Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) 20120101 |
| [Perspectives of prevention and treatment of herpes symplex with regular recurrence]. | Terapevticheskii arkhiv 20110101 |
| Synthesis, cytotoxicity, antiviral activity and interferon inducing ability of 6-(2-aminoethyl)-6H-indolo[2,3-b]quinoxalines. | European journal of medicinal chemistry 20100301 |
| Performance of tiloronoxim and tilorone determination in human blood by HPLC-MS/MS: method validation, uncertainty assessment and its application to a pharmacokinetic study. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100201 |
| Small molecule activation of adaptive gene expression: tilorone or its analogs are novel potent activators of hypoxia inducible factor-1 that provide prophylaxis against stroke and spinal cord injury. | Annals of the New York Academy of Sciences 20081201 |
| Simultaneous quantification of tiloronoxim and tilorone in human urine by liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081115 |
| Chemically induced accumulation of GAGs delays PrP(Sc) clearance but prolongs prion disease incubation time. | Cellular and molecular neurobiology 20081101 |
| alpha7 nicotinic acetylcholine receptor agonist properties of tilorone and related tricyclic analogues. | British journal of pharmacology 20080301 |
| DNA binding of tilorone: 1H NMR and calorimetric studies of the intercalation. | Biochemistry 20070710 |
| [Interferonogenic activity of amixin analogs and diphenyl derivatives]. | Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) 20070101 |
| Possible implication of macrophages in the regulation of cytochrome P450 activities in carp (Cyprinus carpio). | Fish & shellfish immunology 20060701 |
| [Individual changes of gene expression in the interferon system in human blood cells due to amixin and cycloferon]. | Voprosy virusologii 20050101 |
| [Interferon status of patients with non-specific ulcerous colitis and its correction with interferon inducers]. | Terapevticheskii arkhiv 20020101 |
| [Intestinal microflora in rats under the conditions of a chronic toxic lesion of the liver]. | Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20020101 |
| Correlations between in vitro effects of preparations of interferon and its inducers on blood cells in patients with multiple sclerosis. | Bulletin of experimental biology and medicine 20010401 |
| Antiviral and interferon-inducing properties of interferon inducers administered with prostaglandins. | Antimicrobial agents and chemotherapy 19800301 |
| Effects of tilorone hydrochloride on experimental flavivirus infections in mice. | Acta virologica 19770301 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.