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254-60-4 | 1,8-Diazanaphthalene
CAS No: 254-60-4 Catalog No: AG0032NM MDL No:MFCD00059751
Product Description
Catalog Number:
AG0032NM
Chemical Name:
1,8-Diazanaphthalene
CAS Number:
254-60-4
Molecular Formula:
C8H6N2
Molecular Weight:
130.1466
MDL Number:
MFCD00059751
IUPAC Name:
1,8-naphthyridine
InChI:
InChI=1S/C8H6N2/c1-3-7-4-2-6-10-8(7)9-5-1/h1-6H
InChI Key:
FLBAYUMRQUHISI-UHFFFAOYSA-N
SMILES:
c1cnc2c(c1)cccn2
UNII:
043R04VL4M
Properties
Complexity:
102
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
130.053g/mol
Formal Charge:
0
Heavy Atom Count:
10
Hydrogen Bond Acceptor Count:
2
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
130.15g/mol
Monoisotopic Mass:
130.053g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
25.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.5
Literature
| Title | Journal |
|---|---|
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| Methyl 1-ethyl-7-methyl-4-oxo-1,4-di-hydro-1,8-naphthyridine-3-carboxyl-ate monohydrate. | Acta crystallographica. Section E, Structure reports online 20120301 |
| Enhancement of affinity in molecular recognition via hydrogen bonds by POSS-core dendrimer and its application for selective complex formation between guanosine triphosphate and 1,8-naphthyridine derivatives. | Organic & biomolecular chemistry 20120107 |
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| μ-Bis(5,7-dimethyl-1,8-naphthyridin-2-yl)diazene]bis-[difluoridoboron(III). | Acta crystallographica. Section E, Structure reports online 20090701 |
| 1-Ethyl-N'-[(E)-4-hydroxy-benzyl-idene]-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carbohydrazide. | Acta crystallographica. Section E, Structure reports online 20090401 |
| 7-(2,2-Dimethylpropanamido)-2-methyl-1,8-naphthyridin-1-ium chloride monohydrate. | Acta crystallographica. Section E, Structure reports online 20090201 |
| A 1,8-naphthyridine-based fluorescent chemodosimeter for the rapid detection of Zn2+ and Cu2+. | Organic letters 20081120 |
| Synthesis of binuclear platinum complexes containing the ligands 8-naphthyridine, 2-aminopyridine, and 7-azaindolate. An experimental study of the steric hindrance of the bulky pentafluorophenyl ligands in the synthesis of binuclear complexes. | Inorganic chemistry 20081006 |
| 2,2'-Dimethyl-7,7'-(methyl-enediimino)di-1,8-naphthyridin-1-ium bis-(perchlorate). | Acta crystallographica. Section E, Structure reports online 20080901 |
| Allosteric inhibitors of Akt1 and Akt2: a naphthyridinone with efficacy in an A2780 tumor xenograft model. | Bioorganic & medicinal chemistry letters 20080601 |
| Quantitative structure-activity relationship study on affinity profile of a series of 1,8-naphthyridine antagonists toward bovine adenosine receptors. | Journal of enzyme inhibition and medicinal chemistry 20080601 |
| Naphthyridine-based helical foldamers and macrocycles: synthesis, cation binding, and supramolecular assemblies. | The Journal of organic chemistry 20080404 |
| cis,trans-Dicarbonyl-dichlorido[2-(2-pyrid-yl)-1,8-naphthyridine-κN,N]ruthenium(II). | Acta crystallographica. Section E, Structure reports online 20080301 |
| One-pot solvent free synthesis and DNA binding studies of thieno[2,3-b]-1,8-naphthyridines. | Preparative biochemistry & biotechnology 20080101 |
| Effect of an alkyl amino group on the binding of 1,8-naphthyridines to AP site-containing DNA duplexes. | Nucleic acids symposium series (2004) 20080101 |
| Dichloridobis(7-amino-2,4-dimethyl-1,8-naphthyridine-κN,N')cobalt(II) methanol disolvate. | Acta crystallographica. Section E, Structure reports online 20080101 |
| Bis(7-amino-2,4-dimethyl-1,8-naphthyridine)dinitratocadmium(II). | Acta crystallographica. Section E, Structure reports online 20080101 |
| 7-Acetyl-amino-2,4-dimethyl-1,8-naphthyridine. | Acta crystallographica. Section E, Structure reports online 20080101 |
| 7-[4-(5,7-Dimethyl-1,8-naphthyridin-2-yl-oxy)phen-oxy]-2,4-dimethyl-1,8-naphthyridine methanol disolvate. | Acta crystallographica. Section E, Structure reports online 20080101 |
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| Photochromism of photoenolizable ketones in quinoline and 1,8-naphthyridine series studied by time-resolved absorption spectroscopy. | The journal of physical chemistry. A 20070315 |
| Oxacalixarenes and oxacyclophanes containing 1,8-naphthyridines: a new class of molecular tweezers with concave-surface functionality. | Chemical communications (Cambridge, England) 20070314 |
| Synthesis and spectral investigations of manganese(II), cobalt(II), nickel(II), copper(II) and zinc(II) complexes of new polydentate ligands containing a 1,8-naphthyridine moiety. | Molecules (Basel, Switzerland) 20061221 |
| Effects of anti-inflammatory [1, 2, 4]triazolo[4, 3-a] [1, 8]naphthyridine derivatives on human stimulated PMN and endothelial cells: an in vitro study. | Journal of inflammation (London, England) 20060101 |
| 1,8-Naphthyridin-4-one derivatives as new ligands of A2A adenosine receptors. | Bioorganic & medicinal chemistry letters 20051015 |
| Structure-phototoxicity relationship in Balb/c mice treated with fluoroquinolone derivatives, followed by ultraviolet-A irradiation. | Toxicology letters 20050704 |
| Tetrakis(mu(2)-1,8-naphthyridine)-1:2kappa(4)N:N';3:4kappa(4)N:N'-bis(mu(2)-salicylato)-1:4kappa(2)O:O';2:3kappa(2)O:O'-tetrakis(salicylic acid)-1kappaO,2kappaO,3kappaO,4kappaO-tetrasilver(I)(4 Ag-Ag). | Acta crystallographica. Section C, Crystal structure communications 20050601 |
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| Synthesis of 3- or 4-phenyl-1,8-naphthyridine derivatives and evaluation of antimycobacterial and antimicrobial activity. | Farmaco (Societa chimica italiana : 1989) 20030901 |
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