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25389-94-0 | D-Streptamine, O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-, sulfate (1:1)
CAS No: 25389-94-0 Catalog No: AG00352L MDL No:MFCD00070253
Product Description
Catalog Number:
AG00352L
Chemical Name:
D-Streptamine, O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-, sulfate (1:1)
CAS Number:
25389-94-0
Molecular Formula:
C18H38N4O15S
Molecular Weight:
582.5771
MDL Number:
MFCD00070253
IUPAC Name:
(2R,3S,4S,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol;sulfuric acid
InChI:
InChI=1S/C18H36N4O11.H2O4S/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17;1-5(2,3)4/h4-18,23-29H,1-3,19-22H2;(H2,1,2,3,4)/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-;/m1./s1
InChI Key:
OOYGSFOGFJDDHP-KMCOLRRFSA-N
SMILES:
OS(=O)(=O)O.OC[C@H]1O[C@H](O[C@H]2[C@H](N)C[C@@H]([C@H]([C@@H]2O)O[C@H]2O[C@H](CN)[C@H]([C@@H]([C@H]2O)O)O)N)[C@@H]([C@H]([C@@H]1O)N)O
UNII:
J80EX28SMQ
Properties
Complexity:
720
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2
Defined Atom Stereocenter Count:
15
Defined Bond Stereocenter Count:
0
Exact Mass:
582.205g/mol
Formal Charge:
0
Heavy Atom Count:
38
Hydrogen Bond Acceptor Count:
19
Hydrogen Bond Donor Count:
13
Isotope Atom Count:
0
Molecular Weight:
582.575g/mol
Monoisotopic Mass:
582.205g/mol
Rotatable Bond Count:
6
Topological Polar Surface Area:
366A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
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| Chloramphenicol and kanamycin resistance among porcine Escherichia coli in Ontario. | The Journal of antimicrobial chemotherapy 20060701 |
| Aminoglycoside ototoxicity in three murine strains and effects on NKCC1 of stria vascularis. | Chinese medical journal 20060620 |
| Rac/Rho pathway regulates actin depolymerization induced by aminoglycoside antibiotics. | Journal of neuroscience research 20060601 |
| Development of immunoassays for the detection of kanamycin in veterinary fields. | Journal of veterinary science 20060601 |
| Chromone derivatives from the filamentous fungus Lachnum sp. BCC 2424. | Journal of natural products 20060601 |
| Determination of tobramycin in human serum by capillary electrophoresis with contactless conductivity detection. | Electrophoresis 20060501 |
| [A case of severe intestinal tuberculosis, treated with ciprofloxacin, kanamycin and prednisolone]. | Kekkaku : [Tuberculosis] 20060401 |
| rmlB and rmlC genes are essential for growth of mycobacteria. | Biochemical and biophysical research communications 20060331 |
| Development and validation of a novel LC non-derivatization method for the determination of amikacin in pharmaceuticals based on evaporative light scattering detection. | Journal of pharmaceutical and biomedical analysis 20060318 |
| Determination of tobramycin and impurities using high-performance anion exchange chromatography with integrated pulsed amperometric detection. | Journal of pharmaceutical and biomedical analysis 20060303 |
| THE ECONOMICS OF ADVERSE DRUG REACTIONS--case studies. | The Annals of pharmacotherapy 20060301 |
| Analysis of kanamycin A in human plasma and in oral dosage form by derivatization with 1-naphthyl isothiocyanate and high-performance liquid chromatography. | Journal of separation science 20060301 |
| Low light and low ammonium are key factors for guayule leaf tissue shoot organogenesis and transformation. | Plant cell reports 20060201 |
| 2,3-Dihydroxybenzoic acid attenuates kanamycin-induced volume reduction in mouse utricular type I hair cells. | Hearing research 20060201 |
| [Study on factors influencing Agrobacterium-mediated transformation of Jatropha curcas]. | Fen zi xi bao sheng wu xue bao = Journal of molecular cell biology 20060201 |
| 2-substituted furans from the roots of Polyalthia evecta. | Journal of natural products 20060101 |
| [Case of pulmonary mycobacterium avium complex disease, showing hypersensitivity pneumonitis-like diffuse shadow]. | Kekkaku : [Tuberculosis] 20060101 |
| [Kanamycin induced ototoxicity in three kinds of mouse strains and its effects on the expression of na-K-2Cl co-transporter-1 in stria vascularis]. | Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery 20060101 |
| [The rates of resistance to second-line drugs in multidrug resistant Mycobacterium tuberculosis strains]. | Mikrobiyoloji bulteni 20060101 |
| Detection of methicillin/oxacillin resistance and typing in aminoglycoside-susceptible methicillin-resistant and kanamycin-tobramycin-resistant methicillin-susceptible Staphylococcus aureus. | Microbial drug resistance (Larchmont, N.Y.) 20060101 |
| [Resistance of Mycobacterium tuberculosis strains to antimycobacterial preparations]. | Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) 20060101 |
| [The role of aminoglycoside--modifying enzymes in resistance of Gram-negative rods]. | Medycyna doswiadczalna i mikrobiologia 20060101 |
| Efficacy and safety of kanamycin, ethionamide, PAS and cycloserine in multidrug-resistant pulmonary tuberculosis patients. | The Indian journal of chest diseases & allied sciences 20060101 |
| Transgenic grasspea (Lathyrus sativus L.): factors influencing agrobacterium-mediated transformation and regeneration. | Plant cell reports 20051101 |
| Resistance among Escherichia coli to sulphonamides and other antimicrobials now little used in man. | The Journal of antimicrobial chemotherapy 20051101 |
| Enhanced catalytic efficiency of aminoglycoside phosphotransferase (3')-IIa achieved through protein fragmentation and reassembly. | Journal of molecular biology 20051014 |
| Glycodiversification for the optimization of the kanamycin class aminoglycosides. | Journal of medicinal chemistry 20051006 |
| Effect of melanin produced by a recombinant Escherichia coli on antibacterial activity of antibiotics. | Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 20051001 |
| Kanamycin reveals the role played by glutamate receptors in shaping plant resource allocation. | The Plant journal : for cell and molecular biology 20050801 |
| Molecular analysis of cross-resistance to capreomycin, kanamycin, amikacin, and viomycin in Mycobacterium tuberculosis. | Antimicrobial agents and chemotherapy 20050801 |
| Tuning the regioselectivity of the Staudinger reaction for the facile synthesis of kanamycin and neomycin class antibiotics with N-1 modification. | Organic letters 20050707 |
| Intracellular kinase inhibitors selected from combinatorial libraries of designed ankyrin repeat proteins. | The Journal of biological chemistry 20050701 |
| 3-Nitropropionic acid (3-NPA), a potent antimycobacterial agent from endophytic fungi: is 3-NPA in some plants produced by endophytes? | Journal of natural products 20050701 |
| Resprouting and survival of guinea pig cochlear neurons in response to the administration of the neurotrophins brain-derived neurotrophic factor and neurotrophin-3. | The Journal of comparative neurology 20050627 |
| A phosphoethanolamine transferase specific for the outer 3-deoxy-D-manno-octulosonic acid residue of Escherichia coli lipopolysaccharide. Identification of the eptB gene and Ca2+ hypersensitivity of an eptB deletion mutant. | The Journal of biological chemistry 20050603 |
| Kanamycin ototoxicity in glutamate transporter knockout mice. | Neuroscience letters 20050603 |
| Kanamycin A-derived cationic lipids as vectors for gene transfection. | Chembiochem : a European journal of chemical biology 20050601 |
| Melanin potentiates kanamycin-induced inhibition of collagen biosynthesis in human skin fibroblasts. | Die Pharmazie 20050601 |
| Restriction of DNA encoding selectable markers decreases the transformation efficiency of Helicobacter pylori. | FEMS immunology and medical microbiology 20050501 |
| [Two cases of Mycobacterium szulgai pulmonary disease in the elderly]. | Kekkaku : [Tuberculosis] 20050501 |
| NF-kappaB pathway protects cochlear hair cells from aminoglycoside-induced ototoxicity. | Journal of neuroscience research 20050301 |
| Effect of charge transfer bands on the photo-induced DNA cleavage activity of [1-(2-thiazolylazo)-2-naphtholato]copper(II) complexes. | Journal of inorganic biochemistry 20050301 |
| Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals. | Nature medicine 20050301 |
| Changes in transient receptor potential cation channel superfamily V (TRPV) mRNA expression in the mouse inner ear ganglia after kanamycin challenge. | Hearing research 20050301 |
| Resistance of multidrug-resistant strains of Mycobacterium tuberculosis from the Archangel oblast, Russia, to second-line anti-tuberculosis drugs. | European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20050301 |
| Optimization of expression and purification of two biologically active chimeric fusion proteins that consist of human interleukin-13 and Pseudomonas exotoxin in Escherichia coli. | Protein expression and purification 20050201 |
| Transposon mutagenesis identifies genes which control antimicrobial drug tolerance in stationary-phase Escherichia coli. | FEMS microbiology letters 20050201 |
| Rapid and selective micellar electrokinetic chromatography for simultaneous determination of amikacin, kanamycin A, and tobramycin with UV detection and application in drug formulations. | Electrophoresis 20050201 |
| New bioactive clerodane diterpenoids from the bark of Casearia grewiifolia. | Journal of natural products 20050201 |
| Second-line drug susceptibilities of Thai multidrug-resistant Mycobacterium tuberculosis isolates. | The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20050201 |
| Kanamycin incorporation in lipid vesicles prepared by ethanol injection designed for tuberculosis treatment. | The Journal of pharmacy and pharmacology 20050101 |
| [Changes in electrophysical properties of Escherichia coli K-12 cells under the action of kanamycin and tetracycline]. | Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20050101 |
| Comparison of spontaneous antibiotic resistance frequency of Salmonella Typhimurium growth in glucose amended continuous culture at slow and fast dilution rates. | Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20050101 |
| Regulation of mitochondrial uncoupling proteins in mouse inner ear ganglion cells in response to systemic kanamycin challenge. | Neuroscience 20050101 |
| Proteomic analysis of the sarcosine-insoluble outer membrane fraction of Pseudomonas aeruginosa responding to ampicilin, kanamycin, and tetracycline resistance. | Journal of proteome research 20050101 |
| Effects of aminoglycoside administration on cochlear elements in human temporal bones. | Auris, nasus, larynx 20041201 |
| Thermodynamics of aminoglycoside binding to aminoglycoside-3'-phosphotransferase IIIa studied by isothermal titration calorimetry. | Biochemistry 20041123 |
| In vitro bactericidal activity of antimicrobial agents against enterohaemorrhagic Escherichia coli. | The Journal of antimicrobial chemotherapy 20041101 |
| [The relationship between the fragment deletion of mtDNA in old rat and the sensitivity to aminoglycoside antibiotic induced deafness]. | Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology 20041101 |
| Aminoglycoside antibiotics aggregate to form starch-like fibers on negatively charged surfaces and on phage lambda-DNA. | Langmuir : the ACS journal of surfaces and colloids 20041012 |
| The Neisseria meningitidis serogroup A capsular polysaccharide O-3 and O-4 acetyltransferase. | The Journal of biological chemistry 20041008 |
| Chemoenzymatic synthesis and high-throughput screening of an aminoglycoside-polyamine library: identification of high-affinity displacers and DNA-binding ligands. | Journal of the American Chemical Society 20041006 |
| A rapid and highly efficient method for transformation of sugarcane callus. | Molecular biotechnology 20041001 |
| Overexpression and characterization of an aminoglycoside 6'-N-acetyltransferase with broad specificity from an epsilon-poly-L-lysine producer, Streptomyces albulus IFO14147. | Journal of biochemistry 20041001 |
| Natural antioxidant L-carnosine inhibits LPO intensification in structures of the auditory analyzer under conditions of chronic exposure to aminoglycoside antibiotics. | Bulletin of experimental biology and medicine 20041001 |
| A gene cluster for biosynthesis of kanamycin from Streptomyces kanamyceticus: comparison with gentamicin biosynthetic gene cluster. | Archives of biochemistry and biophysics 20040915 |
| Metabolic fate of orally administered phyllodulcin in rats. | Journal of natural products 20040901 |
| Mutant acetolactate synthase gene is an efficient in vitro selectable marker for the genetic transformation of Brassica juncea (oilseed mustard). | Journal of plant physiology 20040901 |
| Identification and functional analysis of dTDP-glucose-4,6-dehydratase gene and its linked gene cluster in an aminoglycoside antibiotics producer of Streptomyces tenebrarius H6. | Current microbiology 20040801 |
| Microbiological/clinical characteristics and validation of topical therapy with kanamycin in aerobic vaginitis: a pilot study. | International journal of antimicrobial agents 20040701 |
| Halomonas anticariensis sp. nov., from Fuente de Piedra, a saline-wetland wildfowl reserve in Malaga, southern Spain. | International journal of systematic and evolutionary microbiology 20040701 |
| Aminoglycoside toxicity: daily versus thrice-weekly dosing for treatment of mycobacterial diseases. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040601 |
| Antibiotic susceptibility of coagulase-negative staphylococci isolated from goats' milk. | International journal of antimicrobial agents 20040601 |
| New bioactive prenylflavonoids and dibenzocycloheptene derivative from roots of Dendrolobium lanceolatum. | Journal of natural products 20040601 |
| An efficient method for sonication assisted Agrobacterium-mediated transformation of coat protein (CP) coding genes into papaya (Carica papaya L.). | Shi yan sheng wu xue bao 20040601 |
| Use of a novel allele of the Escherichia coli aacC4 aminoglycoside resistance gene as a genetic marker in mycobacteria. | FEMS microbiology letters 20040515 |
| Genetic variation at the tomato Cf-4/Cf-9 locus induced by EMS mutagenesis and intralocus recombination. | Genetics 20040501 |
| D-lactic acidosis in short-bowel syndrome managed with antibiotics and probiotics. | Journal of pediatric surgery 20040401 |
| Obtaining transgenic plants using the bio-active beads method. | Journal of plant research 20040401 |
| Fluorinated aminoglycosides and their mechanistic implication for aminoglycoside 3'-phosphotransferases from Gram-negative bacteria. | Biochemistry 20040309 |
| Evaluation of the Escherichia coli threonine deaminase gene as a selectable marker for plant transformation. | Planta 20040301 |
| Lakoochins A and B, new antimycobacterial stilbene derivatives from Artocarpus lakoocha. | Journal of natural products 20040301 |
| Self-administered, standardized regimens for multidrug-resistant tuberculosis in South Korea. | The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20040301 |
| Regioselective glycosylation of neamine core: a facile entry to kanamycin B related analogues. | Organic letters 20040219 |
| Mutation analysis of the different tfd genes for degradation of chloroaromatic compounds in Ralstonia eutropha JMP134. | Archives of microbiology 20040201 |
| Escherichia coli expressing recombinant antigen and listeriolysin O stimulate class I-restricted CD8+ T cells following uptake by human APC. | Journal of immunology (Baltimore, Md. : 1950) 20040201 |
| Epidemiology of Salmonella enterica serotype typhi infections in Korea for recent 9 years: trends of antimicrobial resistance. | Journal of Korean medical science 20040201 |
| Co-administration of kanamycin and ethacrynic acid as a deafening method for acute animal experiments. | Hearing research 20040101 |
| [Etiopathogenetic therapy in adolescent patients with drug-resistant Mycobacterium tuberculosis in respiratory tuberculosis]. | Problemy tuberkuleza i boleznei legkikh 20040101 |
| [Bactericidal therapy in patients with tuberculosis]. | Problemy tuberkuleza i boleznei legkikh 20040101 |
| [Changes in drug resistance of Mycobacteria in the simultaneous use of chemotherapy and intravenous infusions of dissolved ozone]. | Problemy tuberkuleza i boleznei legkikh 20040101 |
| Adjuvant interferon gamma in patients with drug - resistant pulmonary tuberculosis: a pilot study. | BMC infectious diseases 20040101 |
| [Plasmid spectra and phagotypes of Escherichia coli strains isolated from patients with large intestine tumours]. | Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) 20040101 |
| Agrobacterium-mediated transformation of polyploid cereals. The efficiency of selection and transgene expression in wheat. | Cellular & molecular biology letters 20040101 |
| [Interaction of aminoglycosides and the other antibiotic on selected bacterial strains]. | Medycyna doswiadczalna i mikrobiologia 20040101 |
| [M. tuberculosis drug resistance and occurrence in patients with pulmonary tuberculosis]. | Likars'ka sprava 20031201 |
| [Activity of fosfomycin against Escherichia coli O157:H7--morphological changes and production of Shiga toxins]. | The Japanese journal of antibiotics 20031201 |
| Biosynthesis of epsilon-poly-L-lysine in a cell-free system of Streptomyces albulus. | Biochemical and biophysical research communications 20031121 |
| Targeting RNA with small molecules. | Chembiochem : a European journal of chemical biology 20031006 |
| Genetic transformation and regeneration of rubber tree (Hevea brasiliensis Muell. Arg) transgenic plants with a constitutive version of an anti-oxidative stress superoxide dismutase gene. | Plant cell reports 20031001 |
| Desynchronization of electrically evoked auditory-nerve activity by high-frequency pulse trains of long duration. | The Journal of the Acoustical Society of America 20031001 |
| Improved neural representation of vowels in electric stimulation using desynchronizing pulse trains. | The Journal of the Acoustical Society of America 20031001 |
| Antimicrobial drug susceptibility of Staphylococcus aureus strains isolated from bovine and ovine mammary glands. | Journal of dairy science 20031001 |
| A new micellar electrokinetic capillary chromatography method for separation of the components of the aminoglycoside antibiotics. | Electrophoresis 20030901 |
| Changes in cell proliferation in rat and guinea pig cochlea after aminoglycoside-induced damage. | Neuroscience letters 20030828 |
| Ethylene inhibitors and low kanamycin concentrations improve adventitious regeneration from apricot leaves. | Plant cell reports 20030801 |
| Early antibiotic selection and efficient rooting and acclimatization improve the production of transgenic plum plants (Prunus domestica L.). | Plant cell reports 20030801 |
| Transposon-5 mutagenesis transforms Corynebacterium matruchotii to synthesize novel hybrid fatty acids that functionally replace corynomycolic acid. | The Biochemical journal 20030715 |
| Production of Hevea brasiliensis transgenic embryogenic callus lines by Agrobacterium tumefaciens: roles of calcium. | Plant cell reports 20030701 |
| Successful treatment of a LifeSite Hemodialysis Access System pocket infection with large-volume kanamycin solution irrigation. | Advances in renal replacement therapy 20030701 |
| Gene replacement without selection: regulated suppression of amber mutations in Escherichia coli. | Gene 20030605 |
| Molecular analysis of the plasmid-borne aacA/aphD resistance gene region of coagulase-negative staphylococci from chickens. | The Journal of antimicrobial chemotherapy 20030601 |
| Endogenous oxidoreductase expression is induced by aminoglycosides. | Archives of biochemistry and biophysics 20030601 |
| Tanshinone (Salviae miltiorrhizae extract) preparations attenuate aminoglycoside-induced free radical formation in vitro and ototoxicity in vivo. | Antimicrobial agents and chemotherapy 20030601 |
| New antimycobacterial and antimalarial 8,9-secokaurane diterpenes from Croton kongensis. | Journal of natural products 20030601 |
| Anilinopyrimidines as novel antituberculosis agents. | Bioorganic & medicinal chemistry letters 20030519 |
| Resonance Rayleigh scattering spectra for studying the interaction of aminoglycoside antibiotics with pontamine sky blue and their analytical applications. | Analytical and bioanalytical chemistry 20030501 |
| Antimalarial dihydroisocoumarins produced by Geotrichum sp., an endophytic fungus of Crassocephalum crepidioides. | Journal of natural products 20030501 |
| Antimycobacterial pimarane diterpenes from the Fungus Diaporthe sp. | Bioorganic & medicinal chemistry letters 20030407 |
| In vitro oxidative activity of cupric complexes of kanamycin A in comparison to in vivo bactericidal efficacy. | Journal of inorganic biochemistry 20030401 |
| Antimycobacterial activity of phorbol esters from the fruits of Sapium indicum. | Journal of natural products 20030401 |
| Binary transformation systems based on 'shooter' mutants of Agrobacterium tumefaciens: a simple, efficient and universal gene transfer technology that permits marker gene elimination. | Plant cell reports 20030401 |
| Establishment of a highly efficient transformation system for pepper (Capsicum annuum L.). | Plant cell reports 20030401 |
| Transgene expression in broccoli (Brassica oleracea var. italica) clones propagated in vitro via leaf explants. | Plant cell reports 20030401 |
| Inhibition of bacterial IF2 binding to fMet-tRNA((fMet)) by aminoglycosides. | Bioorganic & medicinal chemistry letters 20030324 |
| The crystal structure of aminoglycoside-3'-phosphotransferase-IIa, an enzyme responsible for antibiotic resistance. | Journal of molecular biology 20030321 |
| Construction and complementation of the first auxotrophic mutant in the spirochaete Leptospira meyeri. | Microbiology (Reading, England) 20030301 |
| The decline of high drug resistance rate of pulmonary Mycobacterium tuberculosis isolates from a southern Taiwan medical centre, 1996-2000. | International journal of antimicrobial agents 20030301 |
| Determination of kanamycin by electrophoretically mediated microanalysis with in-capillary derivatization and UV detection. | Electrophoresis 20030301 |
| Sinorhizobium americanus sp. nov., a new Sinorhizobium species nodulating native Acacia spp. in Mexico. | Systematic and applied microbiology 20030301 |
| Determination of kanamycin in serum by solid-phase extraction, pre-capillary derivatization and capillary electrophoresis. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030205 |
| Selection of RRE RNA binding peptides using a kanamycin antitermination assay. | RNA (New York, N.Y.) 20030201 |
| Antibacterial activity and cytotoxicity of extractives from Uvaria hamiltonii stem bark. | Fitoterapia 20030201 |
| Increased Agrobacterium-mediated transformation and rooting efficiencies in canola (Brassica napus L.) from hypocotyl segment explants. | Plant cell reports 20030201 |
| Electroporation and stable maintenance of plasmid DNAs in a biocontrol strain of Pseudomonas syringae. | Biotechnology letters 20030201 |
| Comparison of the changes in global gene expression of Escherichia coli induced by four bactericidal agents. | Journal of molecular microbiology and biotechnology 20030101 |
| [Acute purulent sphenoiditis complicated by paresis of abducens nerve]. | Vestnik otorinolaringologii 20030101 |
| Evaluation of a new agar medium containing cetrimide, kanamycin and nalidixic acid for isolation and enhancement of pigment production of Pseudomonas aeruginosa in clinical samples. | Journal of basic microbiology 20030101 |
| [Construction of vector plasmids for the Plectonema boryanum cyanobacterium and creation, on such basis, of the vector-host system]. | Molekuliarnaia genetika, mikrobiologiia i virusologiia 20030101 |
| A model for the efficacy of combined inhibitors. | Journal of applied microbiology 20030101 |
| Lambda Red-mediated recombinogenic engineering of enterohemorrhagic and enteropathogenic E. coli. | BMC molecular biology 20030101 |
| [A case of pulmonary multiresistant Mycobacterium bovis tuberculosis in Madagascar]. | Archives de l'Institut Pasteur de Madagascar 20030101 |
| [Morphologic studies of the protective role of catechin on kanamycin otoneurotoxicity in SD rats]. | Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 20021228 |
| Dual action of olivocochlear collaterals in the guinea pig cochlear nucleus. | Hearing research 20021201 |
| Cloning, overexpression, and purification of aminoglycoside antibiotic 3-acetyltransferase-IIIb: conformational studies with bound substrates. | Biochemistry 20020903 |
| Fetal central auditory system metabolic response to cochlear implant stimulation. | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20020901 |
| Hirsutellide A, a new antimycobacterial cyclohexadepsipeptide from the entomopathogenic fungus Hirsutella kobayasii. | Journal of natural products 20020901 |
| [Determination of procaine hydrochloride by fluorimetry]. | Guang pu xue yu guang pu fen xi = Guang pu 20020801 |
| Accumulation of the lipid A precursor UDP-2,3-diacylglucosamine in an Escherichia coli mutant lacking the lpxH gene. | The Journal of biological chemistry 20020719 |
| Use of molecular techniques to distinguish between treatment failure and exogenous reinfection with Mycobacterium tuberculosis. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020715 |
| A convenient synthetic pathway for multivalent assembly of aminoglycoside antibiotics starting from amikacin. | Bioorganic & medicinal chemistry letters 20020708 |
| Hearing loss and nephrotoxicity in long-term aminoglycoside treatment in patients with tuberculosis. | The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20020701 |
| Development and validation of capillary electrophoresis method for tobramycin with precapillary derivatization and UV detection. | Electrophoresis 20020601 |
| Intra-cochlear administration of dexamethasone attenuates aminoglycoside ototoxicity in the guinea pig. | Hearing research 20020501 |
| Actinobacillus pleuropneumoniae serotype 1 carrying the defined aroA mutation is fully avirulent in the pig. | Research in veterinary science 20020401 |
| Protective effect of calcium channel blocker verapamil on morphological and functional state of hair cells of the organ of corti in experimental kanamycin-induced ototoxicity. | Bulletin of experimental biology and medicine 20020401 |
| EDTA-dependent pseudothrombocytopenia confirmed by supplementation of kanamycin; a case report. | The Korean journal of internal medicine 20020301 |
| Inhibition of bacterial RNase P by aminoglycoside-arginine conjugates. | FEBS letters 20020130 |
| [Diversity within a population of Shigella sonnei according to markers of medicinal preparations]. | Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20020101 |
| [Intestinal microflora in rats under the conditions of a chronic toxic lesion of the liver]. | Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20020101 |
| [Evaluation of the influence of deep geomagnetic impacting on growth rate and sensitivity to antibiotics in Escherichia coli]. | Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20020101 |
| Aminoglycoside-derived cationic lipids as efficient vectors for gene transfection in vitro and in vivo. | The journal of gene medicine 20020101 |
| A Streptomyces rimosus aphVIII gene coding for a new type phosphotransferase provides stable antibiotic resistance to Chlamydomonas reinhardtii. | Gene 20011017 |
| Aminoglycoside binding to human and bacterial A-Site rRNA decoding region constructs. | Bioorganic & medicinal chemistry 20011001 |
| The antimicrobial approach to caries management. | Journal of dental education 20011001 |
| [Study on intergenera fusion of protoplasts from Rhizobium leguminosorum and Sinorhizobium xinjiangnesis]. | Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20010901 |
| Development of systemic bacteraemia after oral inoculation of vancomycin-resistant enterococci in mice. | Journal of medical microbiology 20010801 |
| Aminoglycoside ototoxicity in adult CBA, C57BL and BALB mice and the Sprague-Dawley rat. | Hearing research 20010801 |
| Phomoxanthones A and B, novel xanthone dimers from the endophytic fungus Phomopsis species. | Journal of natural products 20010801 |
| Development and validation of a simple capillary zone electrophoresis method for the analysis of kanamycin sulfate with UV detection after pre-capillary derivatization. | Journal of chromatography. A 20010727 |
| An integrated method for the enrichment and selective isolation of Actinokineospora spp. in soil and plant litter. | Journal of applied microbiology 20010701 |
| In vitro selection of RNA against kanamycin B. | Molecules and cells 20010630 |
| Molecular mechanism of aminoglycoside antibiotic kinase APH(3')-IIIa: roles of conserved active site residues. | The Journal of biological chemistry 20010629 |
| Cloning, overexpression, and purification of aminoglycoside antibiotic nucleotidyltransferase (2'')-Ia: conformational studies with bound substrates. | Biochemistry 20010619 |
| Kanamycin susceptibility testing of Mycobacterium tuberculosis using Mycobacterium Growth Indicator Tube and a colorimetric method. | Antimicrobial agents and chemotherapy 20010601 |
| Cochlear microphonic potentials: a new recording technique. | The Annals of otology, rhinology, and laryngology 20010601 |
| Efficacy and safety of sparfloxacin in combination with kanamycin and ethionamide in multidrug-resistant pulmonary tuberculosis patients: preliminary results. | The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20010601 |
| Germ-line transformation of Arabidopsis lasiocarpa. | Transgenic research 20010601 |
| EDTA-induced pseudo-neutropenia resolved with kanamycin. | Clinical and laboratory haematology 20010601 |
| The polycationic aminoglycosides modulate the vasoconstrictive effects of endothelin: relevance to cerebral vasospasm. | British journal of pharmacology 20010501 |
| Sterile preparation of antibiotic-selective LB agar plates using a microwave oven. | BioTechniques 20010501 |
| Study of aminoglycoside-nucleic acid interactions by an HPLC method. | Bioorganic & medicinal chemistry letters 20010423 |
| Optimisation and standardisation of a method for detecting and enumerating bacteriophages infecting Bacteroides fragilis. | Journal of virological methods 20010401 |
| Regiospecificity assignment for the reaction of kanamycin nucleotidyltransferase from Staphylococcus aureus. | Biochemistry 20010306 |
| Characterization of the transition-state structure of the reaction of kanamycin nucleotidyltransferase by heavy-atom kinetic isotope effects. | Biochemistry 20010306 |
| Development of liquid chromatographic method for the analysis of kanamycin residues in varicella vaccine using phenylisocyanate as a derivatization reagent. | Journal of chromatography. B, Biomedical sciences and applications 20010305 |
| Potent antiviral potamogetonyde and potamogetonol, new furanoid labdane diterpenes from Potamogeton malaianus. | Journal of natural products 20010301 |
| Antimicrobial susceptibility of Listeria monocytogenes isolated from meningoencephalitis in sheep. | International journal of antimicrobial agents 20010301 |
| Targeted site-specific cleavage of HIV-1 viral Rev responsive element by copper aminoglycosides. | Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20010201 |
| Liposome-mediated DNA uptake and transient expression in Thermotoga. | Extremophiles : life under extreme conditions 20010201 |
| The frequency of silencing in Arabidopsis thaliana varies highly between progeny of siblings and can be influenced by environmental factors. | Transgenic research 20010101 |
| Overexpression of copper/zinc-superoxide dismutase protects from kanamycin-induced hearing loss. | Audiology & neuro-otology 20010101 |
| [Components of monitoring drug resistance of tuberculosis agent in the evaluation of effectiveness of the national tuberculosis control program]. | Problemy tuberkuleza 20010101 |
| Modification of non-protein thiols contents in transgenic tobacco plants producing bacterial enzymes of cysteine biosynthesis pathway. | Acta biochimica Polonica 20010101 |
| Anti-human immunodeficiency virus activity of novel aminoglycoside-arginine conjugates at early stages of infection. | AIDS research and human retroviruses 20000501 |
| Temporal bone studies of the human peripheral vestibular system. Aminoglycoside ototoxicity. | The Annals of otology, rhinology & laryngology. Supplement 20000501 |
| [The role of mtDNA deletion in the sensitivity to aminoglycoside antibiotic induced deafness]. | Zhonghua er bi yan hou ke za zhi 20000401 |
| Aminoglycoside-arginine conjugates that bind TAR RNA: synthesis, characterization, and antiviral activity. | Biochemistry 20000321 |
| Expression of glutamate receptors in the cochlea of the normal and kanamycin-deaf rats. | Advances in oto-rhino-laryngology 20000101 |
| Mechanism of resistance to amikacin and kanamycin in Mycobacterium tuberculosis. | Antimicrobial agents and chemotherapy 19980501 |
| Electrically evoked auditory brainstem response and Fos-immunoreactivity in kanamycin-deafened rats. | Advances in oto-rhino-laryngology 19970101 |
| N-methyl-D-aspartate antagonists limit aminoglycoside antibiotic-induced hearing loss. | Nature medicine 19961201 |
| Activity of KRM-1648 alone or in combination with both ethambutol and kanamycin or clarithromycin against Mycobacterium intracellulare infections in beige mice. | Antimicrobial agents and chemotherapy 19960201 |
| How effective is KRM-1648 in treatment of disseminated Mycobacterium avium complex infections in beige mice? | Antimicrobial agents and chemotherapy 19960201 |
| Ototoxicity of aminoglycoside drugs in tuberculosis treatment. | The South African journal of communication disorders = Die Suid-Afrikaanse tydskrif vir Kommunikasieafwykings 19960101 |
| Onset of ototoxicity in the cat is related to onset of auditory function. | Hearing research 19951201 |
| Cochlear pathology following chronic electrical stimulation of the auditory nerve: II. Deafened kittens. | Hearing research 19941201 |
| The ototoxicity of 3,3'-iminodipropionitrile: functional and morphological evidence of cochlear damage. | Hearing research 19941101 |
| Partial hearing loss in the macaque following the co-administration of kanamycin and ethacrynic acid. | Hearing research 19940101 |
| Profound hearing loss in the cat following the single co-administration of kanamycin and ethacrynic acid. | Hearing research 19931101 |
| Small molecules that selectively block RNA binding of HIV-1 Rev protein inhibit Rev function and viral production. | Cell 19930924 |
| Neuroplasticity of the adult primate auditory cortex following cochlear hearing loss. | The American journal of otology 19930501 |
| [Acute kidney failure due to obstruction of the upper urinary tract during the use of aminocaproic acid]. | Terapevticheskii arkhiv 19930101 |
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