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Home > Sulfanilamide > 25182-53-0
25182-53-0 | 1,3,4-THIADIAZOLE-2-SULFONAMIDE
CAS No: 25182-53-0 Catalog No: AG002QSH MDL No:MFCD18805221
Product Description
Catalog Number:
AG002QSH
Chemical Name:
1,3,4-THIADIAZOLE-2-SULFONAMIDE
CAS Number:
25182-53-0
Molecular Formula:
C2H3N3O2S2
Molecular Weight:
165.1941
MDL Number:
MFCD18805221
IUPAC Name:
1,3,4-thiadiazole-2-sulfonamide
InChI:
InChI=1S/C2H3N3O2S2/c3-9(6,7)2-5-4-1-8-2/h1H,(H2,3,6,7)
InChI Key:
AXNSXSNCIZLUMJ-UHFFFAOYSA-N
SMILES:
NS(=O)(=O)c1scnn1
Properties
Complexity:
183
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
164.967g/mol
Formal Charge:
0
Heavy Atom Count:
9
Hydrogen Bond Acceptor Count:
6
Hydrogen Bond Donor Count:
1
Isotope Atom Count:
0
Molecular Weight:
165.185g/mol
Monoisotopic Mass:
164.967g/mol
Rotatable Bond Count:
1
Topological Polar Surface Area:
123A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.7
Literature
| Title | Journal |
|---|---|
| An alternative purification method for human serum paraoxonase 1 and its interactions with sulfonamides. | Chemical biology & drug design 20101201 |
| Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. | Bioorganic & medicinal chemistry letters 20100801 |
| Carbonic anhydrase inhibitors. Aromatic/heterocyclic sulfonamides incorporating phenacetyl, pyridylacetyl and thienylacetyl tails act as potent inhibitors of human mitochondrial isoforms VA and VB. | Bioorganic & medicinal chemistry 20090715 |
| Carbonic anhydrase inhibitors. Phenacetyl-, pyridylacetyl- and thienylacetyl-substituted aromatic sulfonamides act as potent and selective isoform VII inhibitors. | Bioorganic & medicinal chemistry letters 20090615 |
| Carbonic anhydrase inhibitors: copper(II) complexes of polyamino-polycarboxylamido aromatic/heterocyclic sulfonamides are very potent inhibitors of the tumor-associated isoforms IX and XII. | Bioorganic & medicinal chemistry letters 20080115 |
| Carbonic anhydrase inhibitors. Inhibition of mitochondrial isozyme V with aromatic and heterocyclic sulfonamides. | Journal of medicinal chemistry 20040226 |
| Cyclodextrin complexes of sulfonamide carbonic anhydrase inhibitors as long-lasting topically acting antiglaucoma agents. | Journal of pharmaceutical sciences 20021001 |
| Bile acid derivatives of 5-amino-1,3,4-thiadiazole-2-sulfonamide as new carbonic anhydrase inhibitors: synthesis and investigation of inhibition effects. | Bioorganic & medicinal chemistry 20020801 |
| Carbonic anhydrase inhibitors. Preparation of potent sulfonamides inhibitors incorporating bile acid tails. | Bioorganic & medicinal chemistry letters 20020617 |
| Carbonic anhydrase inhibitors: anticonvulsant sulfonamides incorporating valproyl and other lipophilic moieties. | Journal of medicinal chemistry 20020117 |
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