200,000+ products from a single source!
sales@angenechem.com
2516-93-0 | Acetic acid, 2-butoxy-
CAS No: 2516-93-0 Catalog No: AG002QP4 MDL No:MFCD00067044
Product Description
Catalog Number:
AG002QP4
Chemical Name:
Acetic acid, 2-butoxy-
CAS Number:
2516-93-0
Molecular Formula:
C6H12O3
Molecular Weight:
132.1577
MDL Number:
MFCD00067044
IUPAC Name:
2-butoxyacetic acid
InChI:
InChI=1S/C6H12O3/c1-2-3-4-9-5-6(7)8/h2-5H2,1H3,(H,7,8)
InChI Key:
AJQOASGWDCBKCJ-UHFFFAOYSA-N
SMILES:
CCCCOCC(=O)O
NSC Number:
10980
Properties
Complexity:
80.4
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
132.079g/mol
Formal Charge:
0
Heavy Atom Count:
9
Hydrogen Bond Acceptor Count:
3
Hydrogen Bond Donor Count:
1
Isotope Atom Count:
0
Molecular Weight:
132.159g/mol
Monoisotopic Mass:
132.079g/mol
Rotatable Bond Count:
5
Topological Polar Surface Area:
46.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.9
Literature
| Title | Journal |
|---|---|
| Urinary biomarkers of exposure to glycol ethers and chlorinated solvents during pregnancy: determinants of exposure and comparison with indirect methods of exposure assessment. | Occupational and environmental medicine 20120101 |
| Biological monitoring of low-level 2-butoxyethanol exposure in decal transfer workers in bicycle manufacturing factories. | Occupational and environmental medicine 20111001 |
| Fomepizole fails to prevent progression of acidosis in 2-butoxyethanol and ethanol coingestion. | Clinical toxicology (Philadelphia, Pa.) 20100701 |
| Decrease of intracellular pH as possible mechanism of embryotoxicity of glycol ether alkoxyacetic acid metabolites. | Toxicology and applied pharmacology 20100601 |
| Determination of butoxyacetic acid (biomarker of ethylene glycol monobutyl ether exposure) in human urine candidate reference material. | Analytical and bioanalytical chemistry 20100501 |
| The role of hypoxia in 2-butoxyethanol-induced hemangiosarcoma. | Toxicological sciences : an official journal of the Society of Toxicology 20100101 |
| Relative developmental toxicity of glycol ether alkoxy acid metabolites in the embryonic stem cell test as compared with the in vivo potency of their parent compounds. | Toxicological sciences : an official journal of the Society of Toxicology 20090701 |
| Metabolism of butoxyethanol in excised human skin in vitro. | Toxicology letters 20080401 |
| Potential for metabolism locally in the skin of dermally absorbed compounds. | Human & experimental toxicology 20080401 |
| Metabolism and disposition of n-butyl glycidyl ether in F344 rats and B6C3F1 mice. | Drug metabolism and disposition: the biological fate of chemicals 20071201 |
| Priming dose of phenylhydrazine protects against hemolytic and lethal effects of 2-butoxyethanol. | Toxicology and applied pharmacology 20071115 |
| Development of a gas chromatographic test for the quantitation of the biomarker 2-butoxyacetic acid in urine samples. | Journal of chromatographic science 20070801 |
| Percutaneous absorption and metabolism of 2-butoxyethanol in human volunteers: a microdialysis study. | Toxicology letters 20070425 |
| Pyrazole and methylpyrazole for the treatment of 2-butoxyethanol poisoning. | Acta poloniae pharmaceutica 20070101 |
| Mechanisms of 2-butoxyethanol-induced hemangiosarcomas. | Toxicological sciences : an official journal of the Society of Toxicology 20060801 |
| Gas chromatography analysis of urinary alkoxyacetic acids as biomarkers of exposure to aliphatic alkyl ethers. | Journal of analytical toxicology 20060501 |
| Physiologically based pharmacokinetic modelling of human exposure to 2-butoxyethanol. | Toxicology letters 20060410 |
| Comparison and evaluation of analysis procedures for the quantification of (2-methoxyethoxy)acetic acid in urine. | Analytical and bioanalytical chemistry 20050901 |
| INRS activities on risk assessment of glycol ethers. | Toxicology letters 20050328 |
| Butoxyacetic acid-induced hemolysis of rat red blood cells: effect of external osmolarity and cations. | Toxicology letters 20050328 |
| Effects of diethylene glycol butyl ether and butoxyethoxyacetic acid on rat and human erythrocytes. | Toxicology letters 20050328 |
| Mode of action of butoxyethanol-induced mouse liver hemangiosarcomas and hepatocellular carcinomas. | Toxicology letters 20050328 |
| Determination of age and gender differences in biochemical processes affecting the disposition of 2-butoxyethanol and its metabolites in mice and rats to improve PBPK modeling. | Toxicology letters 20050328 |
| A Test Procedure for the Determination of (2-Methoxyethoxy)acetic Acid in Urine from Jet Fuel-Exposed Mice. | Toxicology mechanisms and methods 20050101 |
| Percutaneous penetration and metabolism of 2-butoxyethanol. | Archives of toxicology 20041101 |
| Free and total urinary 2-butoxyacetic acid following dermal and inhalation exposure to 2-butoxyethanol in human volunteers. | International archives of occupational and environmental health 20041101 |
| Determination of urinary metabolites of alkyl cellosolves by solid phase extraction and GC/FID. | Journal of occupational health 20040701 |
| In vivo metabolism and kinetics of ethylene glycol monobutyl ether and its metabolites, 2-butoxyacetaldehyde and 2-butoxyacetic acid, as measured in blood, liver and forestomach of mice. | Xenobiotica; the fate of foreign compounds in biological systems 20040701 |
| Percutaneous absorption of neat and aqueous solutions of 2-butoxyethanol in volunteers. | International archives of occupational and environmental health 20040201 |
| Synthesis, characterization, and use of 2-[(2H(9))butoxy]acetic acid and 2-(3-methylbutoxy)acetic acid as an internal standard and an instrument performance surrogate, respectively, for the gas chromatographic-mass spectrometric determination of 2-butoxyacetic acid, a human metabolite of 2-butoxyethanol. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030725 |
| Mode of action and pharmacokinetic studies of 2-butoxyethanol in the mouse with an emphasis on forestomach dosimetry. | Toxicological sciences : an official journal of the Society of Toxicology 20030201 |
| A human exposure study to investigate biological monitoring methods for 2-butoxyethanol. | Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20030101 |
| The development of forestomach tumours in the mouse following exposure to 2-butoxyethanol by inhalation: studies on the mode of action and relevance to humans. | Toxicology 20021202 |
| In vitro sub-hemolytic effects of butoxyacetic acid on human and rat erythrocytes. | Toxicological sciences : an official journal of the Society of Toxicology 20020901 |
| Mechanisms of 2-butoxyethanol carcinogenicity: studies on Syrian Hamster Embryo (SHE) cell transformation. | Toxicological sciences : an official journal of the Society of Toxicology 20020701 |
| Effects of 2-butoxyethanol on hepatic oxidative damage. | Toxicology letters 20020105 |
| Suppression of the contact hypersensitivity response following topical exposure to 2-butoxyethanol in female BALB/c mice. | International journal of toxicology 20020101 |
| Studies on the toxicity of some glycol ethers and alkoxyacetic acids in primary testicular cell cultures. | Toxicology and applied pharmacology 19850701 |
Related Products
Featured Products
© 2019 Angene International Limited. All rights Reserved.