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2491-15-8 | Glycine, N-formyl-
CAS No: 2491-15-8 Catalog No: AG002PUN MDL No:MFCD00037360
Product Description
Catalog Number:
AG002PUN
Chemical Name:
Glycine, N-formyl-
CAS Number:
2491-15-8
Molecular Formula:
C3H5NO3
Molecular Weight:
103.0767
MDL Number:
MFCD00037360
IUPAC Name:
2-formamidoacetic acid
InChI:
InChI=1S/C3H5NO3/c5-2-4-1-3(6)7/h2H,1H2,(H,4,5)(H,6,7)
InChI Key:
UGJBHEZMOKVTIM-UHFFFAOYSA-N
SMILES:
O=CNCC(=O)O
EC Number:
219-649-8
UNII:
11F24CG16M
NSC Number:
15826
Properties
Complexity:
80.2
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
103.027g/mol
Formal Charge:
0
Heavy Atom Count:
7
Hydrogen Bond Acceptor Count:
3
Hydrogen Bond Donor Count:
2
Isotope Atom Count:
0
Molecular Weight:
103.077g/mol
Monoisotopic Mass:
103.027g/mol
Rotatable Bond Count:
2
Topological Polar Surface Area:
66.4A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.9
Literature
| Title | Journal |
|---|---|
| Site-specific chemical protein conjugation using genetically encoded aldehyde tags. | Nature protocols 20120510 |
| Examining the promiscuous phosphatase activity of Pseudomonas aeruginosa arylsulfatase: a comparison to analogous phosphatases. | Proteins 20120401 |
| Morquio A syndrome due to maternal uniparental isodisomy of the telomeric end of chromosome 16. | Molecular genetics and metabolism 20120301 |
| Divergence and convergence in enzyme evolution. | The Journal of biological chemistry 20120102 |
| Hypoxia reduces arylsulfatase B activity and silencing arylsulfatase B replicates and mediates the effects of hypoxia. | PloS one 20120101 |
| High-density transcriptional initiation signals underline genomic islands in bacteria. | PloS one 20120101 |
| Structure-activity relationship for the first-in-class clinical steroid sulfatase inhibitor Irosustat (STX64, BN83495). | ChemMedChem 20111104 |
| Protein glycoengineering enabled by the versatile synthesis of aminooxy glycans and the genetically encoded aldehyde tag. | Journal of the American Chemical Society 20111012 |
| Aromatase and dual aromatase-steroid sulfatase inhibitors from the letrozole and vorozole templates. | ChemMedChem 20110801 |
| The regulation of sulfur metabolism in Mycobacterium tuberculosis. | PLoS pathogens 20110701 |
| SUMF1 mutations affecting stability and activity of formylglycine generating enzyme predict clinical outcome in multiple sulfatase deficiency. | European journal of human genetics : EJHG 20110301 |
| Computational exploration of the mechanism of alcohol oxidation by dioxygen activated with biquinolyl-containing cu complexes. | Inorganic chemistry 20100405 |
| Sulfatase activities towards the regulation of cell metabolism and signaling in mammals. | Cellular and molecular life sciences : CMLS 20100301 |
| Recent N-atom containing compounds from indo-pacific invertebrates. | Marine drugs 20100101 |
| Molecular basis of multiple sulfatase deficiency, mucolipidosis II/III and Niemann-Pick C1 disease - Lysosomal storage disorders caused by defects of non-lysosomal proteins. | Biochimica et biophysica acta 20090401 |
| Characterization of the arylsulfatase I (ARSI) gene preferentially expressed in the human retinal pigment epithelium cell line ARPE-19. | Molecular vision 20090101 |
| Efficient, chemoselective synthesis of immunomicelles using single-domain antibodies with a C-terminal thioester. | BMC biotechnology 20090101 |
| A new member of the alkaline phosphatase superfamily with a formylglycine nucleophile: structural and kinetic characterisation of a phosphonate monoester hydrolase/phosphodiesterase from Rhizobium leguminosarum. | Journal of molecular biology 20081205 |
| Sulfotransferases, sulfatases and formylglycine-generating enzymes: a sulfation fascination. | Current opinion in chemical biology 20081001 |
| New aldehyde tag sequences identified by screening formylglycine generating enzymes in vitro and in vivo. | Journal of the American Chemical Society 20080917 |
| Function and structure of a prokaryotic formylglycine-generating enzyme. | The Journal of biological chemistry 20080718 |
| In vitro characterization of AtsB, a radical SAM formylglycine-generating enzyme that contains three [4Fe-4S] clusters. | Biochemistry 20080715 |
| The non-catalytic N-terminal extension of formylglycine-generating enzyme is required for its biological activity and retention in the endoplasmic reticulum. | The Journal of biological chemistry 20080425 |
| ERp44 mediates a thiol-independent retention of formylglycine-generating enzyme in the endoplasmic reticulum. | The Journal of biological chemistry 20080307 |
| Paralog of the formylglycine-generating enzyme--retention in the endoplasmic reticulum by canonical and noncanonical signals. | The FEBS journal 20080301 |
| Molecular analysis of SUMF1 mutations: stability and residual activity of mutant formylglycine-generating enzyme determine disease severity in multiple sulfatase deficiency. | Human mutation 20080101 |
| Generation of quinoneimine intermediates in the bioactivation of 3-(N-phenylamino)alanine (PAA) by human liver microsomes: a potential link between eosinophilia-myalgia syndrome and toxic oil syndrome. | Chemical research in toxicology 20071001 |
| Human sulfatases: a structural perspective to catalysis. | Cellular and molecular life sciences : CMLS 20070801 |
| Probing the oxygen-binding site of the human formylglycine-generating enzyme using halide ions. | Acta crystallographica. Section D, Biological crystallography 20070501 |
| SUMF1 enhances sulfatase activities in vivo in five sulfatase deficiencies. | The Biochemical journal 20070415 |
| Formamide as the main building block in the origin of nucleic acids. | BMC evolutionary biology 20070101 |
| Ethanol decreases rat hepatic arylsulfatase A activity levels. | Alcoholism, clinical and experimental research 20061101 |
| Electron transfer in amino acid.nucleic acid base complexes: EPR, ENDOR, and DFT study of X-irradiated N-formylglycine.cytosine complex crystals. | The journal of physical chemistry. A 20060720 |
| Alkaline Phosphatases : Structure, substrate specificity and functional relatedness to other members of a large superfamily of enzymes. | Purinergic signalling 20060601 |
| De novo calcium/sulfur SAD phasing of the human formylglycine-generating enzyme using in-house data. | Acta crystallographica. Section D, Biological crystallography 20050801 |
| Sulphatase activities are regulated by the interaction of sulphatase-modifying factor 1 with SUMF2. | EMBO reports 20050701 |
| Molecular basis for multiple sulfatase deficiency and mechanism for formylglycine generation of the human formylglycine-generating enzyme. | Cell 20050520 |
| Diversity in domain architectures of Ser/Thr kinases and their homologues in prokaryotes. | BMC genomics 20050101 |
| Three-dimensional structures of sulfatases. | Methods in enzymology 20050101 |
| Overexpression of inactive arylsulphatase mutants and in vitro activation by light-dependent oxidation with vanadate. | The Biochemical journal 20040901 |
| Crystal structure of a covalent intermediate of endogenous human arylsulfatase A. | Journal of inorganic biochemistry 20030801 |
| Posttranslational modification of serine to formylglycine in bacterial sulfatases. Recognition of the modification motif by the iron-sulfur protein AtsB. | The Journal of biological chemistry 20030124 |
| Identification of formylglycine in sulfatases by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. | Journal of mass spectrometry : JMS 20030101 |
| Estrone 3-sulfate mimics, inhibitors of estrone sulfatase activity: homology model construction and docking studies. | Biochemistry 20021217 |
| Optosensing properties of fac-Re(CO)(3)(dpknph)Cl (dpknph=di-2-pyridyl ketone p-nitrophenyl hydrazone) toward chemotactic N-formylamino acids. | Talanta 20020408 |
| Characterization of posttranslational formylglycine formation by luminal components of the endoplasmic reticulum. | The Journal of biological chemistry 20011214 |
| Conserved core structure and active site residues in alkaline phosphatase superfamily enzymes. | Proteins 20011201 |
| Heparan N-sulfatase: cysteine 70 plays a role in the enzyme catalysis and processing. | FEBS letters 20010921 |
| 1.3 A structure of arylsulfatase from Pseudomonas aeruginosa establishes the catalytic mechanism of sulfate ester cleavage in the sulfatase family. | Structure (London, England : 1993) 20010601 |
| Crystal structure of an enzyme-substrate complex provides insight into the interaction between human arylsulfatase A and its substrates during catalysis. | Journal of molecular biology 20010112 |
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