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Home > Nitro Compounds > 24554-26-5

24554-26-5

24554-26-5 | Formamide, N-[4-(5-nitro-2-furanyl)-2-thiazolyl]-

CAS No: 24554-26-5 Catalog No: AG002OIY MDL No:

Product Description

Catalog Number:
AG002OIY
Chemical Name:
Formamide, N-[4-(5-nitro-2-furanyl)-2-thiazolyl]-
CAS Number:
24554-26-5
Molecular Formula:
C8H5N3O4S
Molecular Weight:
239.2080
IUPAC Name:
N-[4-(5-nitrofuran-2-yl)-1,3-thiazol-2-yl]formamide
InChI:
InChI=1S/C8H5N3O4S/c12-4-9-8-10-5(3-16-8)6-1-2-7(15-6)11(13)14/h1-4H,(H,9,10,12)
InChI Key:
ZQBWQLJJMGJREB-UHFFFAOYSA-N
SMILES:
O=CNc1scc(n1)c1ccc(o1)[N+](=O)[O-]
UNII:
7N99PZG62O
NSC Number:
155010

Properties

Complexity:
285  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
239g/mol
Formal Charge:
0
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
239.205g/mol
Monoisotopic Mass:
239g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
129A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.4  

Literature

Title Journal
Possible roles of excess tryptophan metabolites in cancer. Environmental and molecular mutagenesis 20110301
Antitumor Efficacy of Intravesical BCG, Gemcitabine, Interferon-α and Interleukin-2 as Mono- or Combination-Therapy for Bladder Cancer in an Orthotopic Tumor Model. Clinical Medicine Insights. Oncology 20110101
A rat model of intravesical delivery of small interfering RNA for studying urinary carcinoma. World journal of urology 20100801
Experimental rat bladder urothelial cell carcinoma models. World journal of urology 20090601
Tumor versus vascular photodamage in a rat tumor model. Journal of photochemistry and photobiology. B, Biology 19980821
Effect of indomethacin on N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide-induced urinary tract carcinogenesis. Carcinogenesis 19950701
Liver NADPH-dependent oxidation of the 5-nitrofurans, FANFT and ANFT, by guinea pig and rat. Xenobiotica; the fate of foreign compounds in biological systems 19930201
Mechanism of formation of the thioether conjugate of the bladder carcinogen 2-amino-4-(5-nitro-2-furyl)-thiazole (ANFT). Carcinogenesis 19921101
Comparative bladder tumor promoting activity of sodium saccharin, sodium ascorbate, related acids, and calcium salts in rats. Cancer research 19910401
Metabolism and disposition of bladder carcinogens in rat and guinea pig: possible mechanism of guinea pig resistance to bladder cancer. Cancer research 19910115
Combined therapy of interleukin 2 with cyclophosphamide or bacillus Calmette-Guérin against implanted bladder cancer cells in mice. Urologia internationalis 19910101
Treatment of the transplantable FANFT induced bladder tumors with the purpurin SnET2 and red light emitted by a pulsed frequency doubled Nd:YAG laser. Journal of laser applications 19910101
Mechanism of peroxidative activation of the bladder carcinogen 2-amino-4-(5-nitro-2-furyl)-thiazole (ANFT): comparison with benzidine. Carcinogenesis 19901101
Characterization of an N-methyl-N-nitrosourea-induced autochthonous rat bladder cancer model. Cancer research 19901015
[Comparison of the effects of various immunosuppressive drugs on subrenal capsule assay (SRC assay)]. Hinyokika kiyo. Acta urologica Japonica 19900701
Dose response relationship of methotrexate in combination with cisplatin in murine bladder cancer. Urology 19900301
Protection from carcinogen-induced murine bladder carcinoma by interferons and an oral interferon-inducing pyrimidinone, bropirimine. Cancer research 19900215
Activating missense mutations in Ha-ras-1 genes in a malignant subset of bladder lesions induced by N-butyl-N-(4-hydroxybutyl)nitrosamine or N-[4-(5-nitro-2-furanyl)-2-thiazolyl]formamide. Molecular carcinogenesis 19900101
Effects of sodium salts of phenobarbital and barbital on development of bladder tumors in male F344/NCr rats pretreated with either N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide or N-nitrosobutyl-4-hydroxybutylamine. Toxicology and applied pharmacology 19890401
Chromosomal characteristics and malignancy of urothelial cells from carcinogen-treated rats. Journal of the National Cancer Institute 19890301
The influence of antipyrene on N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide-induced urinary tract carcinogenesis. Carcinogenesis 19880501
Comparison of single agent cisplatin and cisplatin containing combinations in treatment of murine bladder cancer. Urology 19871101
A dose response analysis of purpurin derivatives used as photosensitizers for the photodynamic treatment of transplantable FANFT induced urothelial tumors. The Journal of urology 19870601
N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide-induced bladder cancer in mice: augmentation by sutures through the bladder wall. The Journal of urology 19870401
Effect of L-tryptophan excess and vitamin B6 deficiency on rat urinary bladder cancer promotion. Cancer research 19870301
Production of urinary tract tumors by co-administration of uracil and N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide in F344 rats. Cancer letters 19870301
Enhancement of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide-induced carcinogenesis by urinary tract infection in rats. Cancer research 19870115
Enhanced expression of Harvey-ras oncogene in FANFT-induced transitional cell carcinoma. Urologia internationalis 19870101
Effect of sodium phenobarbital and sodium saccharin in AIN-76A diet on carcinogenesis initiated with N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide and N,N-dibutylnitrosamine in male F344 rats. Cancer research 19861201
The effect of long-term administration of aspirin and sodium saccharin on the rat kidney. Toxicology and applied pharmacology 19861001
Phototherapy of bladder cancer: dose/effect relationships. The Journal of urology 19860801
Inhibition by aspirin of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide initiation and sodium saccharin promotion of urinary bladder carcinogenesis in male F344 rats. Cancer research 19860801
Influence of the application mode of N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide on the localization of its carcinogenic expression in female NMRI-mice. Cancer letters 19860601
Effect of dose on the induction of urothelial proliferation by N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide and its relationship to bladder carcinogenesis in the rat. Carcinogenesis 19860401
Evaluation of the effects of cotinine and nicotine-N'-oxides on the development of tumors in rats initiated with N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide. Journal of the National Cancer Institute 19851201
The effect of nitrofurantoin on bladder tumor cell lines: in vitro growth and implantation in the cauterized mouse bladder. The Journal of urology 19851201
Role of renal metabolism and excretion in 5-nitrofuran-induced uroepithelial cancer in the rat. The Journal of clinical investigation 19850901
In vitro and in vivo activity of two second generation platinum analogs in murine bladder cancer. The Journal of urology 19850801
Low susceptibility of analbuminemic rats to induction of bladder cancer by N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide. Japanese journal of cancer research : Gann 19850701
Formation of thioether conjugates of the bladder carcinogen ANFT catalyzed by prostaglandin H synthase. Carcinogenesis 19850401
Immunohistochemical study of keratin in proliferative bladder epithelium induced by freezing, cyclophosphamide or N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide in the rat. Carcinogenesis 19850301
Multi-stage carcinogenesis in the urinary bladder. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 19850101
Metabolic activation of the carcinogen N-[4-(5-nitro-2-furyl)-2-thiazolyl]acetamide by prostaglandin H synthase. Carcinogenesis 19841001
Antithyroid drugs interact with renal medullary prostaglandin H synthase. The Journal of laboratory and clinical medicine 19840801
Enhancement by phenothiazine and 2,5-di-O-acetyl-D-glucosaccharo-(1,4)(6,3)-dilactone of bladder carcinogenicity of N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide in rats. Cancer letters 19840801
Carcinogenicity of the antischistosomal nitrofuran trans-5-amino-3-[2-(5-nitro-2-furyl)vinyl]-1,2,4-oxadiazole. Journal of the National Cancer Institute 19840701
Indomethacin and poly I:C in the inhibition of carcinogen-induced bladder cancer in an experimental animal model. The Journal of urology 19840601
The Noble rat bladder cancer model. FANFT-induced tumors. Cancer 19840301
Evaluation of chemotherapy in a murine model for bladder cancer. Oncology 19840101
A murine model for bladder cancer. Progress in clinical and biological research 19840101
Inhibition by aspirin of N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide-induced bladder carcinogenesis and enhancement of forestomach carcinogenesis. Carcinogenesis 19840101
Effect of aspirin on N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide-induced epithelial proliferation in the urinary bladder and forestomach of the rat. Cancer letters 19840101
Metastatic characteristics of four FANFT-induced murine bladder tumors. Urology 19831101
The relationship of histamine H2 receptor-bearing suppressor cells with the growth and metastasis of FANFT-induced bladder cancer. Journal of surgical oncology 19830901
The influence of phenacetin or mechanical perforation on the development of renal pelvic and urinary bladder tumors in FANFT-induced urinary tract carcinogenesis. Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology 19830901
The use of a tumor colony assay in predicting chemotherapeutic drug response in murine bladder cancer. Cancer 19830815
Effect of phenobarbital on the carcinogenesis of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide in rats. Cancer letters 19830701
Long term dose response study of N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide-induced urinary bladder carcinogenesis. Cancer letters 19830401
Multistage carcinogenesis in the urinary bladder. Environmental health perspectives 19830301
Cellular changes in rat urinary bladder carcinomas induced by FANFT: a quantitative electron microscopic analysis. The Journal of urology 19830301
Keyhole-limpet haemocyanin (KLH) immunotherapy of murine transitional cell carcinoma. Urological research 19830101
Co-carcinogenicity of sodium saccharin and N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide for the urinary bladder. Carcinogenesis 19830101
Expression of the cellular immune response during tumor development in an animal model of bladder cancer. The Journal of urology 19821201
Rat bladder isograft model for focal carcinoma. The Journal of urology 19820901
In vitro characterization of four N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide (FANFT) induced mouse bladder tumors. The Journal of urology 19820601
Time- and concentration-dependent inhibition of the clonogenic growth of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide-induced murine bladder tumor cell lines by cis-diamminedichloroplatinum(II). Cancer research 19820301
Single and sequential combination intravesical chemotherapy of murine bladder cancer. Urology 19820201
Growth characteristics of N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide (FANFT)-induced mouse bladder tumor lines in a human tumor stem cell assay. Cancer 19820115
Carcinogenicity of 2-amino-4-(5-nitro-2-furyl) thiazole in rats by oral and subcutaneous administration. Carcinogenesis 19820101
Effect of partial cystectomy on the induction of pre-neoplastic lesions in rat bladder initiated with N-butyl-N-(4-hydroxybutyl)nitrosamine followed by bladder carcinogens and promoters. Urological research 19820101
Maintenance by saccharin of membrane alterations of rat bladder cells induced by subcarcinogenic treatment with bladder carcinogens. Cancer research 19811101
Comparison between a purified and standard diet on FANFT-induced murine bladder cancer. Urology 19811101
Aspirin inhibition of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide-induced lesions of the urinary bladder correlated with inhibition of metabolism by bladder prostaglandin endoperoxide synthetase. Cancer research 19810901
Effect of L-tryptophan and sodium saccharin on urinary tract carcinogenesis initiated by N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide. Cancer research 19810801
The morphologic effects of mitomycin C in mammalian urinary bladder. Cancer 19810601
13-cis-retinoic acid: effect on urinary bladder carcinogenesis by N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide in Fischer rats. Cancer letters 19810501
Potentiation of dimethylhydrazine bowel carcinogenesis in rats. Cancer 19810501
The effect of single dose N-methyl-N-nitrosourea on bladder carcinogenesis by N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide in rats. Investigative urology 19810501
Synthetic retinamides: effect on urinary bladder carcinogenesis by FANFT in Fischer rats. Carcinogenesis 19810101
Effect of sodium saccharin and L-tryptophan on rat urine during bladder carcinogenesis. Cancer research 19810101
Effects of urine and continued exposure to carcinogen on progression of early neoplastic urinary bladder lesions. Cancer research 19801201
Development of an in vitro and in vivo epithelial tumor model for the study of invasion. Cancer research 19801201
Neovascularization in rats during urinary bladder carcinogenesis induced by N-[4-(5-Nitro-2-furyl)-2-thiazolyl]formamide. Journal of the National Cancer Institute 19800701
Induction of a transplantable urinary bladder carcinoma in dogs. Investigative urology 19800701
Early induction of mouse urinary bladder ornithine decarboxylase activity by rodent vesical carcinogens. Cancer research 19800601
Morphological effects of mitomycin C administered intravesically to normal mice and mice with N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide-induce bladder neoplasms. Cancer research 19800201
Potentiation of 1-2-dimethylhydrazine-induced bowel carcinogenesis by the urinary bladder carcinogen N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide. Carcinogenesis 19800201
Galactosyl transferase activity in rat bladder transitional cell carcinoma lines and in exfoliated cells in urine during carcinogenesis and reversible hyperplasia. Cancer biochemistry biophysics 19800101
Immunization by irradiated whole cells or cell extracts against an experimental bladder tumor. Investigative urology 19800101
[Epithelial bladder tumor induction in rats with N-(4-(5-nitro-2-furyl)-2-thiazolyl)formamide]. Voprosy onkologii 19800101
[Chemically induced transplantable carcinomas of the urinary bladder in dogs (author's transl)]. Urologia internationalis 19800101
Intracytoplasmic lumina in bladder carcinomas. Human pathology 19790901
Effect of intralesional and systemic BCG-application or a combined cyclophosphamide/BCG treatment on experimental bladder cancer. Urological research 19790622
Intravesical thio-tepa: a study of 3H-thymidine uptake in normal urothelium and FANFT-induced tumors in rats. Investigative urology 19790501
Effect of dose on urinary bladder carcinogenesis induced in F344 rats by N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide. Journal of the National Cancer Institute 19790401
Promoting effect of saccharin and DL-tryptophan in urinary bladder carcinogenesis. Cancer research 19790401
Intercellular junctions in FANFT-induced carcinomas of rat urinary bladder in tissue culture: in situ thin-section, freeze-fracture, and scanning electron microscopy studies. Journal of microscopy 19790401
Retinyl acetate prophylaxis in cancer of the urinary bladder. Investigative urology 19790301
The effect of platinum analogues and combination chemotherapy on murine bladder cancer. Transactions of the American Association of Genito-Urinary Surgeons 19790101
Topography and numerical densities of intramembrane particles in chemical carcinogen-induced urinary bladder carcinomas in Fischer rats. Laboratory investigation; a journal of technical methods and pathology 19781201
Immunogenicity of N-[-4-(5-nitro-2-furyl)-2-thiazolyl]formamide-induced bladder cancer. National Cancer Institute monograph 19781201
Desmosome ultrastructure and biological behavior of chemical carcinogen-induced urinary bladder carcinomas. Cancer research 19781001
Biological behavior of N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide induced carcinoma of the transitional epithelium in the rat. Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology 19780101
The effects of topical instillation of adriamycin in bladder tumors of rats fed with FANFT. Investigative urology 19780101
Induction of transitional cell carcinoma of the urinary bladder in rats by feeding N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide. Histological and ultrastructural findings. Urological research 19780101
The pathogenesis of bladder cancer. The American journal of pathology 19771101
A long-term study of reversible and progressive urinary bladder cancer lesions in rats fed N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide. Cancer research 19770801
Reverse transcriptase inhibitors and chemically induced bladder tumors in mice. Investigative urology 19770301
Bacillus Calmette-Guérin and dinitrochlorobenzene immunotherapy of chemically induced bladder tumors. Investigative urology 19770301
Uridine 5'-diphosphate galactose: glycoprotein galactosyl transferase activity in exfoliated bladder epithelial cells in rats fed N-(4-(5-nitro-2-furyl)-2-thiazolyl) formamide. Cancer biochemistry biophysics 19770101
Experimental bladder tumor induction, propagation, and therapy. Urology 19760701
Light and scanning electron microscopy of exfoliated bladder epithelial cells in rats fed N-(4-(5-nitro-2-furyl)-2-thiazolyl)formamide. Journal of the National Cancer Institute 19760701
Effect of avitaminosis A and hypervitaminosis A on urinary bladder carcinogenicity of N-(4-(5-Nitro-2-furyl)-2-thiazolyl)formamide. Cancer research 19760701
Early lesions in experimental bladder cancer: experimental design and light microscopic findings. Cancer research 19760701
Early lesions in experimental bladder cancer: scanning electron microscopy of cell surface markers. Cancer research 19760701
Enhancing effect of allopurinol on the induction of bladder cancer in rats by n-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide. Cancer research 19760501
Susceptibility of urothelium to neoplastic cellular implantation. Urology 19750601

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