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CAS No: 2450-71-7 Catalog No: AG002OCW MDL No:MFCD00008198
| Title | Journal |
|---|---|
| Kinetic resolution of propargylamines via a highly enantioselective non-enzymatic N-acylation process. | Chemical communications (Cambridge, England) 20121104 |
| Bacitracin-conjugated superparamagnetic iron oxide nanoparticles: synthesis, characterization and antibacterial activity. | Chemphyschem : a European journal of chemical physics and physical chemistry 20121008 |
| A versatile method for functionalization and grafting of 2-hydroxyethyl cellulose (HEC) via Click chemistry. | Carbohydrate polymers 20121001 |
| Stereoselective intermolecular C-H amination reactions. | Chemical communications (Cambridge, England) 20120814 |
| Site-specific protein propargylation using tissue transglutaminase. | Organic & biomolecular chemistry 20120721 |
| Highly enantioselective synthesis of chiral allenes by sequential creation of stereogenic center and chirality transfer in a single pot operation. | Organic letters 20120615 |
| Site-specific modification of amino acids and peptides by aldehyde-alkyne-amine coupling under ambient aqueous conditions. | Organic letters 20120615 |
| Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted alkyl and cycloalkyl propargyl amine. | European journal of medicinal chemistry 20120601 |
| 6-Bromo-2-(diprop-2-ynyl-amino)-1H-benzo[de]isoquinoline-1,3(2H)-dione. | Acta crystallographica. Section E, Structure reports online 20120601 |
| Cyclocondensation of amino-propargyl silanes. | Organic letters 20120504 |
| Gold(I)-catalyzed unprecedented rearrangement reaction between 2-aminobenzaldehydes with propargyl amines: an expedient route to 3-aminoquinolines. | Chemistry (Weinheim an der Bergstrasse, Germany) 20120427 |
| Silica based click amino stationary phase for ion chromatography and hydrophilic interaction liquid chromatography. | The Analyst 20120407 |
| Efficient iron(III)-catalyzed three-component coupling reaction of alkynes, CH2Cl2 and amines to propargylamines. | Chemical communications (Cambridge, England) 20120214 |
| Highly stereoselective synthesis of cis-β-enaminones mediated by diethyl azodicarboxylate. | Chemical communications (Cambridge, England) 20120207 |
| Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy. | Theranostics 20120101 |
| Synthesis and properties of molecular probes for the rescue site on mutant cystic fibrosis transmembrane conductance regulator. | Journal of medicinal chemistry 20111222 |
| Site-specific labeling of DNA and RNA using an efficiently replicated and transcribed class of unnatural base pairs. | Journal of the American Chemical Society 20111214 |
| The marriage of organocatalysis with metal catalysis: access to multisubstituted chiral 2,5-dihydropyrroles by cascade iminium/enamine-metal cooperative catalysis. | Chemistry (Weinheim an der Bergstrasse, Germany) 20111209 |
| Synthesis of steroid-ferrocene conjugates of steroidal 17-carboxamides via a palladium-catalyzed aminocarbonylation--copper-catalyzed azide-alkyne cycloaddition reaction sequence. | Steroids 20111101 |
| Explaining ADAGIO: a critical review of the biological basis for the clinical effects of rasagiline. | Movement disorders : official journal of the Movement Disorder Society 20111101 |
| Propargylaminyl 3α-hy-droxy-11-oxo-18β-olean-12-en-29-oate. | Acta crystallographica. Section E, Structure reports online 20111101 |
| Chemical synthesis of cell-permeable apoptotic peptides from in vivo produced proteins. | Bioconjugate chemistry 20110921 |
| Synthesis, biological assessment and molecular modeling of new multipotent MAO and cholinesterase inhibitors as potential drugs for the treatment of Alzheimer's disease. | European journal of medicinal chemistry 20110901 |
| Propargylamine synthesis by copper-catalyzed oxidative coupling of alkynes and tertiary amine N-oxides. | The Journal of organic chemistry 20110819 |
| Gold(I) catalysts with bifunctional P, N ligands. | Inorganic chemistry 20110815 |
| Electrochemical impedance spectroscopy sensor for ascorbic acid based on copper(I) catalyzed click chemistry. | Biosensors & bioelectronics 20110715 |
| Epidermal growth factor-PEG functionalized PAMAM-pentaethylenehexamine dendron for targeted gene delivery produced by click chemistry. | Biomacromolecules 20110613 |
| Medical management of Parkinson's disease: focus on neuroprotection. | Current neuropharmacology 20110601 |
| Versatility of alkyne-modified poly(glycidyl methacrylate) layers for click reactions. | Langmuir : the ACS journal of surfaces and colloids 20110517 |
| Fluoride-cleavable, fluorescently labelled reversible terminators: synthesis and use in primer extension. | Chemistry (Weinheim an der Bergstrasse, Germany) 20110301 |
| MAO-inhibitors in Parkinson's Disease. | Experimental neurobiology 20110301 |
| Amphiphilic amylose-g-poly(meth)acrylate copolymers through 'click' onto grafting method. | Biomacromolecules 20110214 |
| Star polymers composed entirely of amino acid building blocks: a route towards stereospecific, biodegradable and hierarchically functionalized stars. | Chemical communications (Cambridge, England) 20110128 |
| Enhanced chiral recognition by cyclodextrin dimers. | International journal of molecular sciences 20110101 |
| Controversies in neurology: why monoamine oxidase B inhibitors could be a good choice for the initial treatment of Parkinson's disease. | BMC neurology 20110101 |
| Methods for Activity Analysis of the Proteins that Regulate Histone Methylation. | Current chemical genomics 20110101 |
| Synthesis of specifically modified oligonucleotides for application in structural and functional analysis of RNA. | Journal of nucleic acids 20110101 |
| The promise of neuroprotective agents in Parkinson's disease. | Frontiers in neurology 20110101 |
| Nanomicelle with long-term circulation and enhanced stability of camptothecin based on mPEGylated alpha,beta-poly (L-aspartic acid)-camptothecin conjugate. | Colloids and surfaces. B, Biointerfaces 20101101 |
| A simple method for the preparation of propargylamines using molecular sieve modified with copper(II). | Organic & biomolecular chemistry 20101021 |
| Fine-tuning the morphology of self-assembled nanostructures of propargyl ammonium-based amphiphiles. | The journal of physical chemistry. B 20101007 |
| Merging nucleophilic and hydrogen bonding catalysis: an anion binding approach to the kinetic resolution of propargylic amines. | Journal of the American Chemical Society 20101006 |
| Highly diastereoselective synthesis of α-difluoromethyl amines from N-tert-butylsulfinyl ketimines and difluoromethyl phenyl sulfone. | Chemistry (Weinheim an der Bergstrasse, Germany) 20101004 |
| Mechanistic insights into the one-pot synthesis of propargylamines from terminal alkynes and amines in chlorinated solvents catalyzed by gold compounds and nanoparticles. | Chemistry (Weinheim an der Bergstrasse, Germany) 20100809 |
| Shell-cross-linked micelles from PNIPAM-b-(PLL)2 Y-shaped miktoarm star copolymer as drug carriers. | Biomacromolecules 20100712 |
| Unprecedented Cu(I)-catalyzed microwave-assisted three-component coupling of a ketone, an alkyne, and a primary amine. | Organic letters 20100604 |
| Why do we need multifunctional neuroprotective and neurorestorative drugs for Parkinson's and Alzheimer's diseases as disease modifying agents. | Experimental neurobiology 20100601 |
| New xanthate-based radical cyclization onto alkynes. | Chemical communications (Cambridge, England) 20100414 |
| Comparative analysis of small molecules and histone substrate analogues as LSD1 lysine demethylase inhibitors. | Journal of the American Chemical Society 20100310 |
| Chiral N-phosphonyl imine chemistry: an efficient asymmetric synthesis of chiral N-phosphonyl propargylamines. | Organic & biomolecular chemistry 20100307 |
| Copper-catalyzed enantioselective three-component synthesis of optically active propargylamines from aldehydes, amines, and aliphatic alkynes. | Chemistry (Weinheim an der Bergstrasse, Germany) 20100222 |
| A versatile synthetic platform based on strained propargyl amines. | Angewandte Chemie (International ed. in English) 20100222 |
| TVP1022 protects neonatal rat ventricular myocytes against doxorubicin-induced functional derangements. | The Journal of pharmacology and experimental therapeutics 20100201 |
| Silver(I)-mediated highly enantioselective synthesis of axially chiral allenes under thermal and microwave-assisted conditions. | Chemical communications (Cambridge, England) 20100114 |
| Propargyl amine synthesis catalysed by gold and copper thin films by using microwave-assisted continuous-flow organic synthesis (MACOS). | Chemistry (Weinheim an der Bergstrasse, Germany) 20100104 |
| Propargylamine containing compounds as modulators of proteolytic cleavage of amyloid-beta protein precursor: involvement of MAPK and PKC activation. | Journal of Alzheimer's disease : JAD 20100101 |
| Native chemical ligation in the synthesis of internally modified oligonucleotide-peptide conjugates. | Biopolymers 20100101 |
| Highly selective fluorescent probe for Au3+ based on cyclization of propargylamide. | Chemical communications (Cambridge, England) 20091214 |
| Zn(II)-Catalyzed synthesis of piperidines from propargyl amines and cyclopropanes. | Organic letters 20090820 |
| Functional mechanism of neuroprotection by inhibitors of type B monoamine oxidase in Parkinson's disease. | Expert review of neurotherapeutics 20090801 |
| Iron(III)-catalyzed and air-mediated tandem reaction of aldehydes, alkynes and amines: an efficient approach to substituted quinolines. | Chemistry (Weinheim an der Bergstrasse, Germany) 20090622 |
| Tricyclic thienopyridine-pyrimidones/thienopyrimidine-pyrimidones as orally efficacious mGluR1 antagonists for neuropathic pain. | Bioorganic & medicinal chemistry letters 20090615 |
| Three-component synthesis of N-Boc-4-iodopyrroles and sequential one-pot alkynylation. | Organic letters 20090604 |
| The 'Corey's reagent,' 3,5-di-tert-butyl-1,2-benzoquinone, as a modifying agent in the synthesis of fluorescent and double-headed nucleosides. | Nucleosides, nucleotides & nucleic acids 20090501 |
| Chemoselective C-H bond activation: ligand and solvent free iron-catalyzed oxidative C-C cross-coupling of tertiary amines with terminal alkynes. Reaction scope and mechanism. | Organic letters 20090416 |
| Functionalization of macroporous organic polymer monolith based on succinimide ester reactivity for chiral capillary chromatography: a cyclodextrin click approach. | Macromolecular rapid communications 20090116 |
| Synthesis of diacetylene-containing peptide building blocks and amphiphiles, their self-assembly and topochemical polymerization in organic solvents. | Chemistry (Weinheim an der Bergstrasse, Germany) 20090101 |
| Chemicals possessing a neurotrophin-like activity on dopaminergic neurons in primary culture. | PloS one 20090101 |
| Total synthesis of pentabromo- and pentachloropseudilin, and synthetic analogues--allosteric inhibitors of myosin ATPase. | Angewandte Chemie (International ed. in English) 20090101 |
| Role of rasagiline in treating Parkinson's disease: Effect on disease progression. | Therapeutics and clinical risk management 20090101 |
| A novel feature of intramolecular vibrational redistribution in propargyl alcohol and propargyl amine. | The Journal of chemical physics 20080921 |
| TVP1022 and propargylamine protect neonatal rat ventricular myocytes against doxorubicin-induced and serum starvation-induced cardiotoxicity. | Journal of cardiovascular pharmacology 20080901 |
| Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries. | Natural product reports 20080801 |
| Clorgyline and other propargylamine derivatives as inhibitors of succinate-dependent H(2)O(2) release at NADH:UBIQUINONE oxidoreductase (Complex I) in brain mitochondria. | Journal of bioenergetics and biomembranes 20080801 |
| A new polymorph of N-(prop-2-yn-yl)tricyclo-[3.3.1.1]decane-1-carbox-amide. | Acta crystallographica. Section E, Structure reports online 20080801 |
| New hydroxypyridinone iron-chelators as potential anti-neurodegenerative drugs. | Frontiers in bioscience : a journal and virtual library 20080501 |
| Genetic findings in Parkinson's disease and translation into treatment: a leading role for mitochondria? | Genes, brain, and behavior 20080301 |
| The phosphate site of trehalose phosphorylase from Schizophyllum commune probed by site-directed mutagenesis and chemical rescue studies. | The FEBS journal 20080301 |
| Gold-catalyzed highly enantioselective synthesis of axially chiral allenes. | Organic letters 20080207 |
| Rasagiline in treatment of Parkinson's disease. | Neuropsychiatric disease and treatment 20080201 |
| Enantioselective copper-catalyzed propargylic amination. | Angewandte Chemie (International ed. in English) 20080101 |
| A highly efficient and selective Au(I)-catalyzed tandem synthesis of diversely substituted pyrrolo[1,2-a]quinolines in aqueous media. | Angewandte Chemie (International ed. in English) 20080101 |
| Physiological and pathological aspects of Abeta in iron homeostasis via 5'UTR in the APP mRNA and the therapeutic use of iron-chelators. | BMC neuroscience 20080101 |
| Chronic experimental diabetes accelerates urinary elimination of deprenyl and its metabolites. | The open medicinal chemistry journal 20080101 |
| Induction of neurotrophic factors GDNF and BDNF associated with the mechanism of neurorescue action of rasagiline and ladostigil: new insights and implications for therapy. | Annals of the New York Academy of Sciences 20071201 |
| Diastereoselective alkynylation of N-p-tolylsulfinylimines with aluminum acetylides. | The Journal of organic chemistry 20071012 |
| One-pot synthesis of new A-ring fused steroidal pyridines. | Steroids 20071001 |
| Comprehensive review of rasagiline, a second-generation monoamine oxidase inhibitor, for the treatment of Parkinson's disease. | Clinical therapeutics 20070901 |
| Rapid, efficient synthesis of heterobifunctional biodegradable dendrimers. | Journal of the American Chemical Society 20070606 |
| Mitochondrial nutrition as a strategy for neuroprotection in Parkinson's disease—research focus in the department of alternative medicine and experimental therapeutics at Hokuriku University. | Evidence-based complementary and alternative medicine : eCAM 20070601 |
| Rasagiline - a novel MAO B inhibitor in Parkinson's disease therapy. | Therapeutics and clinical risk management 20070601 |
| Grafting of poly[2-(tert-butylamino)ethyl methacrylate] onto polypropylene by reactive blending and antibacterial activity of the copolymer. | Biomacromolecules 20070401 |
| A clickable inhibitor reveals context-dependent autoactivation of p90 RSK. | Nature chemical biology 20070301 |
| A RSK kinase inhibitor reporting its selectivity in vivo. | Nature chemical biology 20070301 |
| Efficient ruthenium and copper cocatalzyed five-component coupling to form dipropargyl amines under mild conditions in water. | Organic & biomolecular chemistry 20070207 |
| Therapeutic targets and potential of the novel brain- permeable multifunctional iron chelator-monoamine oxidase inhibitor drug, M-30, for the treatment of Alzheimer's disease. | Journal of neurochemistry 20070101 |
| Neuroprotection by propargylamines in Parkinson's disease: intracellular mechanism underlying the anti-apoptotic function and search for clinical markers. | Journal of neural transmission. Supplementum 20070101 |
| EPR studies of amine radical cations. Part 2. Thermal and photo-induced rearrangements of propargylamine and allylamine radical cations in low-temperature freon matrices. | The journal of physical chemistry. A 20061228 |
| A new consecutive three-component oxazole synthesis by an amidation-coupling-cycloisomerization (ACCI) sequence. | Chemical communications (Cambridge, England) 20061214 |
| Implications of co-morbidity for etiology and treatment of neurodegenerative diseases with multifunctional neuroprotective-neurorescue drugs; ladostigil. | Neurotoxicity research 20061201 |
| Aminopropargyl derivative of terpyridine-bis(methyl-enamine) tetraacetic acid chelate of europium (Eu (TMT)-AP3): a new reagent for fluorescent labelling of proteins and peptides. | Organic & biomolecular chemistry 20061121 |
| Direct addition of alkynes to imines and related C=N electrophiles: A convenient access to propargylamines. | Chemical communications (Cambridge, England) 20061104 |
| Solid-phase synthesis of C-terminally modified peptides. | Journal of peptide science : an official publication of the European Peptide Society 20061101 |
| Synthesis of 3-miktoarm stars and 1st generation mikto dendritic copolymers by 'living' radical polymerization and 'click' chemistry. | Journal of the American Chemical Society 20060906 |
| Asymmetric synthesis of alpha,alpha-dibranched propargylamines by acetylide additions to N-tert-butanesulfinyl ketimines. | The Journal of organic chemistry 20060901 |
| [Molecular mechanisms of the neuroprotective effect of (-)-deprenyl]. | Orvosi hetilap 20060709 |
| Microwave assisted 'click' chemistry for the synthesis of multiple labeled-carbohydrate oligonucleotides on solid support. | The Journal of organic chemistry 20060609 |
| Highly enantioselective access to primary propargylamines: 4-piperidinone as a convenient protecting group. | Organic letters 20060525 |
| Practical highly enantioselective synthesis of propargylamines through a copper-catalyzed one-pot three-component condensation reaction. | Chemistry (Weinheim an der Bergstrasse, Germany) 20060524 |
| Rationale for considering that propargylamines might be neuroprotective in Parkinson's disease. | Neurology 20060523 |
| Rasagiline: A second-generation monoamine oxidase type-B inhibitor for the treatment of Parkinson's disease. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20060515 |
| Zinc- and indium-promoted conjugate addition-cyclization reactions of ethenetricarboxylates with propargylamines and alcohol: novel methylenepyrrolidine and methylenetetrahydrofuran syntheses. | The Journal of organic chemistry 20060428 |
| Gold(III) Salen complex-catalyzed synthesis of propargylamines via a three-component coupling reaction. | Organic letters 20060413 |
| A mechanism-based inactivator for histone demethylase LSD1. | Journal of the American Chemical Society 20060412 |
| Antioxidant properties of propargylamine derivatives: assessment of their ability to scavenge peroxynitrite. | The Journal of pharmacy and pharmacology 20060401 |
| Synthesis of oligonucleotides with 3'-terminal 5-(3-acylamidopropargyl)-3'-amino-2',3'-dideoxyuridine residues and their reactivity in single-nucleotide steps of chemical replication. | The Journal of organic chemistry 20060203 |
| N-Propargylamine protects SH-SY5Y cells from apoptosis induced by an endogenous neurotoxin, N-methyl(R)salsolinol, through stabilization of mitochondrial membrane and induction of anti-apoptotic Bcl-2. | Journal of neural transmission (Vienna, Austria : 1996) 20060101 |
| M30, a novel multifunctional neuroprotective drug with potent iron chelating and brain selective monoamine oxidase-ab inhibitory activity for Parkinson's disease. | Journal of neural transmission. Supplementum 20060101 |
| Involvement of multiple survival signal transduction pathways in the neuroprotective, neurorescue and APP processing activity of rasagiline and its propargyl moiety. | Journal of neural transmission. Supplementum 20060101 |
| Modification of Monoaminergic Activity by MAO Inhibitors Influences Methamphetamine Actions. | Drug target insights 20060101 |
| para-Hydrogenation of unsaturated moieties on poly(lysine) derived substrates for the development of novel hyperpolarized MRI contrast agents. | Organic & biomolecular chemistry 20051107 |
| Regulation of Bcl-2 family proteins, neurotrophic factors, and APP processing in the neurorescue activity of propargylamine. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051101 |
| Clinical pharmacology of rasagiline: a novel, second-generation propargylamine for the treatment of Parkinson disease. | Journal of clinical pharmacology 20050801 |
| Novel neuroprotective mechanism of action of rasagiline is associated with its propargyl moiety: interaction of Bcl-2 family members with PKC pathway. | Annals of the New York Academy of Sciences 20050801 |
| Electrostatic stabilization in a pre-organized polar active site: the catalytic role of Lys-80 in Candida tenuis xylose reductase (AKR2B5) probed by site-directed mutagenesis and functional complementation studies. | The Biochemical journal 20050715 |
| Generation of N-heterocyclic carbenes by metal-mediated coupling of propargylamine and isocyanides. | Journal of the American Chemical Society 20050622 |
| A Re(V)-catalyzed C-N bond-forming route to human lipoxygenase inhibitors. | Organic letters 20050609 |
| Neuropharmacological, neuroprotective and amyloid precursor processing properties of selective MAO-B inhibitor antiparkinsonian drug, rasagiline. | Drugs of today (Barcelona, Spain : 1998) 20050601 |
| Mechanism of neuroprotective action of the anti-Parkinson drug rasagiline and its derivatives. | Brain research. Brain research reviews 20050401 |
| Determining the origin of the stabilization of DNA by 5-aminopropynylation of pyrimidines. | Biochemistry 20050329 |
| Synthesis of heterocyclic allenes via palladium-catalyzed hydride-transfer reaction of propargylic amines. | The Journal of organic chemistry 20050318 |
| An efficient synthesis of propargylamines via C-H activation catalyzed by copper(I) in ionic liquids. | Chemical communications (Cambridge, England) 20050314 |
| Bifunctional drug derivatives of MAO-B inhibitor rasagiline and iron chelator VK-28 as a more effective approach to treatment of brain ageing and ageing neurodegenerative diseases. | Mechanisms of ageing and development 20050201 |
| Rasagiline: neurodegeneration, neuroprotection, and mitochondrial permeability transition. | Journal of neuroscience research 20050101 |
| Neuroprotection by rasagiline: a new therapeutic approach to Parkinson's disease? | CNS drug reviews 20050101 |
| CGP 3466B has no effect on disease course of (G93A) mSOD1 transgenic mice. | Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20041201 |
| Preclinical evidence for neuroprotection with monoamine oxidase-B inhibitors in Parkinson's disease. | Neurology 20041012 |
| Novel bifunctional drugs targeting monoamine oxidase inhibition and iron chelation as an approach to neuroprotection in Parkinson's disease and other neurodegenerative diseases. | Journal of neural transmission (Vienna, Austria : 1996) 20041001 |
| CuBr-catalyzed efficient alkynylation of sp3 C-H bonds adjacent to a nitrogen atom. | Journal of the American Chemical Society 20040929 |
| The mechanism of nitrogenase. Computed details of the site and geometry of binding of alkyne and alkene substrates and intermediates. | Journal of the American Chemical Society 20040929 |
| Neuroprotection via pro-survival protein kinase C isoforms associated with Bcl-2 family members. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040901 |
| Differential inhibition of six copper amine oxidases by a family of 4-(aryloxy)-2-butynamines: evidence for a new mode of inactivation. | Biochemistry 20040831 |
| Localization of a catalytic intermediate bound to the FeMo-cofactor of nitrogenase. | The Journal of biological chemistry 20040813 |
| Selective inhibition of bovine plasma amine oxidase by homopropargylamine, a new inactivator motif. | Journal of the American Chemical Society 20040630 |
| Helical polymer carrying helical grafts from peptide-based acetylene macromonomers: synthesis. | Macromolecular bioscience 20040625 |
| Synthesis, characterisation and molecular structure of Re(III) 2-oxacyclocarbenes stabilised by a benzoyldiazenido ligand. | Dalton transactions (Cambridge, England : 2003) 20040307 |
| Neuroprotection by monoamine oxidase B inhibitors: a therapeutic strategy for Parkinson's disease? | BioEssays : news and reviews in molecular, cellular and developmental biology 20040101 |
| Simultaneous analytical method for the determination of TCH346 and its four metabolites in human plasma by liquid chromatography/tandem mass spectrometry. | Rapid communications in mass spectrometry : RCM 20040101 |
| Advances in neuroprotection research for neurodegenerative diseases. | Advances in experimental medicine and biology 20040101 |
| Cytotoxicity, cytoprotection and neurotoxicity of novel deprenyl-related propargylamines, stable nitroxide free radicals, in vitro and in vivo. | In vivo (Athens, Greece) 20040101 |
| The importance of propargylamine moiety in the anti-Parkinson drug rasagiline and its derivatives in MAPK-dependent amyloid precursor protein processing. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20031201 |
| Monoamine oxidase inhibitors l-deprenyl and clorgyline protect nonmalignant human cells from ionising radiation and chemotherapy toxicity. | British journal of cancer 20031117 |
| L-Deprenyl as an inhibitor of menadione-induced permeability transition in liver mitochondria. | Biochemical pharmacology 20031101 |
| TCH346 prevents motor symptoms and loss of striatal FDOPA uptake in bilaterally MPTP-treated primates. | Neurobiology of disease 20031101 |
| Rasagiline: an anti-Parkinson drug with neuroprotective activity. | Expert review of neurotherapeutics 20031101 |
| Inhibition of bovine plasma amine oxidase by 1,4-diamino-2-butenes and -2-butynes. | Bioorganic & medicinal chemistry 20031015 |
| The essentiality of Bcl-2, PKC and proteasome-ubiquitin complex activations in the neuroprotective-antiapoptotic action of the anti-Parkinson drug, rasagiline. | Biochemical pharmacology 20031015 |
| Enantioselective cyclization of alkene radical cations. | Organic letters 20031002 |
| Synthesis of a high-affinity fluorescent PPARgamma ligand for high-throughput fluorescence polarization assays. | Bioorganic & medicinal chemistry 20031001 |
| Three-component enantioselective synthesis of propargylamines through Zr-catalyzed additions of alkyl zinc reagents to alkynylimines. | Angewandte Chemie (International ed. in English) 20030915 |
| Sequential amination/annulation/aromatization reaction of carbonyl compounds and propargylamine: a new one-pot approach to functionalized pyridines. | The Journal of organic chemistry 20030905 |
| Enantioselective synthesis of propargylamines through Zr-catalyzed addition of mixed alkynylzinc reagents to arylimines. | Organic letters 20030904 |
| Synthesis of enantiomerically enriched propargylamines by copper-catalyzed addition of alkynes to enamines. | Chemistry (Weinheim an der Bergstrasse, Germany) 20030616 |
| A novel cholinesterase and brain-selective monoamine oxidase inhibitor for the treatment of dementia comorbid with depression and Parkinson's disease. | Progress in neuro-psychopharmacology & biological psychiatry 20030601 |
| Highly potent propargylamine and allylamine inhibitors of bovine plasma amine oxidase. | Biochemical and biophysical research communications 20030516 |
| Anti-apoptotic action of anti-Alzheimer drug, TV3326 [(N-propargyl)-(3R)-aminoindan-5-yl]-ethyl methyl carbamate, a novel cholinesterase-monoamine oxidase inhibitor. | Neuroscience letters 20030508 |
| Neuroprotection by deprenyl and other propargylamines: glyceraldehyde-3-phosphate dehydrogenase rather than monoamine oxidase B. | Journal of neural transmission (Vienna, Austria : 1996) 20030501 |
| Iterative oxazole assembly via alpha-chloroglycinates: total synthesis of (-)-muscoride A. | Angewandte Chemie (International ed. in English) 20030328 |
| Novel iminium ion equivalents prepared through C-H oxidation for the stereocontrolled synthesis of functionalized propargylic amine derivatives. | Journal of the American Chemical Society 20030226 |
| Protein 4.1N is required for translocation of inositol 1,4,5-trisphosphate receptor type 1 to the basolateral membrane domain in polarized Madin-Darby canine kidney cells. | The Journal of biological chemistry 20030207 |
| Antioxidant properties of newly synthesized N-propargylamine derivatives of nitroxyl: a comparison with deprenyl. | Polish journal of pharmacology 20030101 |
| Synthesis and energy transfer efficiency of FRET terminators derived from different linkers. | Nucleosides, nucleotides & nucleic acids 20030101 |
| Anti-apoptotic function of propargylamine inhibitors of type-B monoamine oxidase. | Inflammopharmacology 20030101 |
| Novel dual inhibitors of AChE and MAO derived from hydroxy aminoindan and phenethylamine as potential treatment for Alzheimer's disease. | Journal of medicinal chemistry 20021121 |
| Stable DNA triple helix formation using oligonucleotides containing 2'-aminoethoxy,5-propargylamino-U. | Biochemistry 20020611 |
| Enantioselective direct-addition of terminal alkynes to imines catalyzed by copper(I)pybox complex in water and in toluene. | Journal of the American Chemical Society 20020522 |
| Propargylamines induce antiapoptotic new protein synthesis in serum- and nerve growth factor (NGF)-withdrawn, NGF-differentiated PC-12 cells. | The Journal of pharmacology and experimental therapeutics 20020501 |
| The anti-Parkinson drug, rasagiline, prevents apoptotic DNA damage induced by peroxynitrite in human dopaminergic neuroblastoma SH-SY5Y cells. | Journal of neural transmission (Vienna, Austria : 1996) 20020401 |
| Pharmacological interventions in aging and age-associated disorders: potentials of propargylamines for human use. | Annals of the New York Academy of Sciences 20020401 |
| Transition-metal-catalyzed reactions of propargylamine with carbon dioxide and carbon disulfide. | The Journal of organic chemistry 20020111 |
| The influence of metabolism on the MAO-B inhibitory potency of selegiline. | Current medicinal chemistry 20020101 |
| Aliphatic propargylamines as symptomatic and neuroprotective treatments for neurodegenerative diseases. | Neurotoxicology and teratology 20020101 |
| Neuroprotection by propargylamines in Parkinson's disease: suppression of apoptosis and induction of prosurvival genes. | Neurotoxicology and teratology 20020101 |
| Cyclization of electron-deficient cyclopentadienone with 2-alkenyl and 2-alkynylamines via sequential pericyclic reaction pathway. | The Journal of organic chemistry 20011228 |
| Molecular basis of neuroprotective activities of rasagiline and the anti-Alzheimer drug TV3326 [(N-propargyl-(3R)aminoindan-5-YL)-ethyl methyl carbamate]. | Cellular and molecular neurobiology 20011201 |
| Novel intramolecular rearrangement of tertiary propargylamine N-oxides. | The Journal of organic chemistry 20011019 |
| Synthesis of N-(3-arylpropyl)amino acid derivatives by Sonogashira types of reaction in aqueous media. | Organic letters 20010906 |
| Antiapoptotic properties of rasagiline, N-propargylamine-1(R)-aminoindan, and its optical (S)-isomer, TV1022. | Annals of the New York Academy of Sciences 20010601 |
| Maintaining mitochondrial membrane impermeability. an opportunity for new therapy in glaucoma? | Survey of ophthalmology 20010501 |
| Do antioxidant strategies work against aging and age-associated disorders? Propargylamines: a possible antioxidant strategy. | Annals of the New York Academy of Sciences 20010401 |
| Phosphoramidites and oligonucleotides containing 7-deazapurines and pyrimidines carrying aminopropargyl side chains. | Nucleosides, nucleotides & nucleic acids 20010101 |
| Novel propargylamine-linked nucleosides for high throughput SNP genotyping by MALDI-TOF MS. | Nucleosides, nucleotides & nucleic acids 20010101 |
| Mechanism-based inactivation of porcine kidney diamine oxidase by 1,4-diamino-2-butene. | Biochimica et biophysica acta 19951115 |
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