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23491-52-3

23491-52-3 | 2,5'-Bi-1H-benzimidazole, 2'-(4-ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-

CAS No: 23491-52-3 Catalog No: AG002NEM MDL No:MFCD00012678

Product Description

Catalog Number:
AG002NEM
Chemical Name:
2,5'-Bi-1H-benzimidazole, 2'-(4-ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-
CAS Number:
23491-52-3
Molecular Formula:
C27H28N6O
Molecular Weight:
452.5508
MDL Number:
MFCD00012678
IUPAC Name:
2-(4-ethoxyphenyl)-6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazole
InChI:
InChI=1S/C27H28N6O/c1-3-34-21-8-4-18(5-9-21)26-28-22-10-6-19(16-24(22)30-26)27-29-23-11-7-20(17-25(23)31-27)33-14-12-32(2)13-15-33/h4-11,16-17H,3,12-15H2,1-2H3,(H,28,30)(H,29,31)
InChI Key:
PRDFBSVERLRRMY-UHFFFAOYSA-N
SMILES:
CCOc1ccc(cc1)c1[nH]c2c(n1)cc(cc2)c1nc2c([nH]1)ccc(c2)N1CCN(CC1)C
EC Number:
245-691-1
UNII:
99KZS6CNZX

Properties

Complexity:
664  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
452.232g/mol
Formal Charge:
0
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
452.562g/mol
Monoisotopic Mass:
452.232g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
73.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
4.6  

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GSK3 beta N-terminus binding to p53 promotes its acetylation. Molecular cancer 20090101
Identification of pro-angiogenic markers in blood vessels from stroked-affected brain tissue using laser-capture microdissection. BMC genomics 20090101
PRIMA-1MET induces nucleolar translocation of Epstein-Barr virus-encoded EBNA-5 protein. Molecular cancer 20090101
Electro-acupuncture promotes survival, differentiation of the bone marrow mesenchymal stem cells as well as functional recovery in the spinal cord-transected rats. BMC neuroscience 20090101
Normal ventral telencephalic expression of Pax6 is required for normal development of thalamocortical axons in embryonic mice. Neural development 20090101
All-trans retinoic acid promotes neural lineage entry by pluripotent embryonic stem cells via multiple pathways. BMC cell biology 20090101
Multiple functions of precursor BDNF to CNS neurons: negative regulation of neurite growth, spine formation and cell survival. Molecular brain 20090101
Gender-based reciprocal expression of transforming growth factor-beta1 and the inducible nitric oxide synthase in a rat model of cyclophosphamide-induced cystitis. Journal of inflammation (London, England) 20090101
Targeted overexpression of a golli-myelin basic protein isoform to oligodendrocytes results in aberrant oligodendrocyte maturation and myelination. ASN neuro 20090101
Tumor necrosis factor alpha-dependent aggrecan cleavage and release of glycosaminoglycans in the meniscus is mediated by nitrous oxide-independent aggrecanase activity in vitro. Arthritis research & therapy 20090101
The role of calcium in apoptosis induced by 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide. Journal of biochemical and molecular toxicology 20090101
AT-101, a small molecule inhibitor of anti-apoptotic Bcl-2 family members, activates the SAPK/JNK pathway and enhances radiation-induced apoptosis. Radiation oncology (London, England) 20090101
Doublecortin-expressing cells persist in the associative cerebral cortex and amygdala in aged nonhuman primates. Frontiers in neuroanatomy 20090101
Stimulation of glioma cell motility by expression, proteolysis, and release of the L1 neural cell recognition molecule. Cancer cell international 20090101
Cerebellar Purkinje cells incorporate immunoglobulins and immunotoxins in vitro: implications for human neurological disease and immunotherapeutics. Journal of neuroinflammation 20090101
A comprehensive analysis of sequence variants and putative disease-causing mutations in photoreceptor-specific nuclear receptor NR2E3. Molecular vision 20090101
Camptothecin and khat (Catha edulis Forsk.) induced distinct cell death phenotypes involving modulation of c-FLIPL, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines. Molecular cancer 20090101
Preferential induction of MLL(Mixed Lineage Leukemia) rearrangements in human lymphocyte cultures treated with etoposide. Genetics and molecular biology 20090101
Biomimetic Yeast Cell Typing-Application of QCMs. Sensors (Basel, Switzerland) 20090101
Rapid detection of Abeta deposits in APP transgenic mice by Hoechst 33342. Neuroscience letters 20081231
N-(4-[2-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-isoquinolinyl)ethyl]-phenyl)-9,10-dihydro-5-methoxy-9-oxo-4-acridine carboxamide (GF120918) as a chemical ATP-binding cassette transporter family G member 2 (Abcg2) knockout model to study nitrofurantoin transfer into milk. Drug metabolism and disposition: the biological fate of chemicals 20081201
Constant pressure fluid infusion into rat neocortex from implantable microfluidic devices. Journal of neural engineering 20081201
Longitudinal in vivo susceptibility contrast MRI measurements of LS174T colorectal liver metastasis in nude mice. Journal of magnetic resonance imaging : JMRI 20081201
Identification of the molecular signatures integral to regenerating photoreceptors in the retina of the zebra fish. Journal of ocular biology, diseases, and informatics 20081201
[Phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway is critical for survival and proliferation of pancreatic cancer stem-like side population cells]. Zhonghua yi xue za zhi 20081118
Cdk5 regulates accurate maturation of newborn granule cells in the adult hippocampus. PLoS biology 20081101
Extracellular clusterin promotes neuronal network complexity in vitro. Neuroreport 20081008
Flow cytometric characterization of the DAOY medulloblastoma cell line for the cancer stem-like phenotype. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20081001
Prenatal ethanol exposure reduces the expression of the transcriptional factor Pax6 in the developing rat brain. Annals of the New York Academy of Sciences 20081001
Multidrug transport by the ABC transporter Sav1866 from Staphylococcus aureus. Biochemistry 20080902
Use of a novel collagen matrix with oriented pore structure for muscle cell differentiation in cell culture and in grafts. Journal of cellular and molecular medicine 20080901
[Effects of hypoxia-ischemia on different neural cells in subventricular zone of human fetus]. Zhonghua er ke za zhi = Chinese journal of pediatrics 20080901
Modification of actions of heat shock on development and apoptosis of cultured preimplantation bovine embryos by oxygen concentration and dithiothreitol. Molecular reproduction and development 20080801
Dequalinium-induced cell death of yeast expressing alpha-synuclein-GFP fusion protein. Neurochemical research 20080701
MAPK kinase kinase-1 is essential for cytokine-induced c-Jun NH2-terminal kinase and nuclear factor-kappaB activation in human pancreatic islet cells. Diabetes 20080701
20-Hydroxyeicosatetraenoic acid inhibits the apoptotic responses in pulmonary artery smooth muscle cells. European journal of pharmacology 20080624
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry 20080612
Monitoring Plasmodium falciparum growth and development by UV flow cytometry using an optimized Hoechst-thiazole orange staining strategy. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20080601
Antiangiogenic and anticolorectal cancer effects of metronomic irinotecan chemotherapy alone and in combination with semaxinib. British journal of cancer 20080520
Cell fusions in mammals. Histochemistry and cell biology 20080501
Sodium salicylate switches glucose depletion-induced necrosis to autophagy and inhibits high mobility group box protein 1 release in A549 lung adenocarcinoma cells. Oncology reports 20080501
Muscle precursor cells in the developing limbs of two isopods (Crustacea, Peracarida): an immunohistochemical study using a novel monoclonal antibody against myosin heavy chain. Development genes and evolution 20080501
Growth inhibition of human colon cancer cell line HCT116 by bis[2-(acylamino)phenyl] disulfide and its action mechanism. Biological & pharmaceutical bulletin 20080501
Antioxidants prevent ethanol-associated apoptosis in fetal rhombencephalic neurons. Brain research 20080414
Induction of chondrogenesis and superficial zone protein accumulation in synovial side population cells by BMP-7 and TGF-beta1. Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20080401
Proteomic analysis of apoptosis induced by xanthoangelol, a major constituent of Angelica keiskei, in neuroblastoma. Biological & pharmaceutical bulletin 20080401
Cationic gradient reversal and cytoskeleton-independent volume regulatory pathways define an early stage of apoptosis. The Journal of biological chemistry 20080314
Fluorescence imaging of cellular glutathione using a latent rhodamine. Organic letters 20080306
TGFalpha and EGFR in ovine preimplantation embryos and effects on development. Animal reproduction science 20080303
Cell-based and biochemical structure-activity analyses of analogs of the microtubule stabilizer dictyostatin. Molecular pharmacology 20080301
Sodium pancratistatin 3,4-o-cyclic phosphate, a water-soluble synthetic derivative of pancratistatin, is highly effective in a human colon tumor model. Journal of natural products 20080301
Characterization of chlorpyrifos-induced apoptosis in placental cells. Toxicology 20080227
Aldo-keto reductase 1C2 is essential for 1-nitropyrene's but not for benzo[a]pyrene's induction of p53 phosphorylation and apoptosis. Toxicology 20080227
On the energy-dependence of Hoechst 33342 transport by the ABC transporter LmrA. Biochemical pharmacology 20080215
Propofol exerts greater neuroprotection with disodium edetate than without it. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20080201
Multiple antiapoptotic targets of the PI3K/Akt survival pathway are activated by epoxyeicosatrienoic acids to protect cardiomyocytes from hypoxia/anoxia. American journal of physiology. Heart and circulatory physiology 20080201
Transforming growth factor-beta-activated protein kinase 1-binding protein (TAB)-1alpha, but not TAB1beta, mediates cytokine-induced p38 mitogen-activated protein kinase phosphorylation and cell death in insulin-producing cells. Endocrinology 20080101
Presence of side-population cells in an immortalized nontumorigenic human liver epithelial cell line. In vitro cellular & developmental biology. Animal 20080101
P53 represses human papillomavirus type 16 DNA replication via the viral E2 protein. Virology journal 20080101
Olfactory ensheathing cells conditioned medium prevented apoptosis induced by 6-OHDA in PC12 cells through modulation of intrinsic apoptotic pathways. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20080101
Prevention of Oxidative Stress-Induced Retinal Pigment Epithelial Cell Death by the PPARgamma Agonists, 15-Deoxy-Delta 12, 14-Prostaglandin J(2). PPAR research 20080101
Decellularizing corneal stroma using N2 gas. Molecular vision 20080101
Brain architecture in the terrestrial hermit crab Coenobita clypeatus (Anomura, Coenobitidae), a crustacean with a good aerial sense of smell. BMC neuroscience 20080101
Flow cytometric analysis of Drosophila cells. Methods in molecular biology (Clifton, N.J.) 20080101
Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity. Molecular brain 20080101
2,2,6,6-tetramethylpiperidin-1-oxyl probes for evaluating oxidative stress on the cell membrane and mitochondria. Methods in molecular biology (Clifton, N.J.) 20080101
Synthesis of glutathione C60 derivative and its protective effect on hydrogen peroxide-induced apoptosis in rat pheochromocytoma cells. Neuroscience letters 20071218
New functional assay of P-glycoprotein activity using Hoechst 33342. Bioorganic & medicinal chemistry 20071201
Murine fertilized ovum, blastomere and morula cells lacking SP phenotype. Science in China. Series C, Life sciences 20071201
Side population cells expressing ABCG2 in human adult dental pulp tissue. International endodontic journal 20071201
Erythroblasts highly express the ABC transporter Bcrp1/ABCG2 but do not show the side population (SP) phenotype. Immunology letters 20071130
Biocompatibility of contact lens solutions using confocal laser scanning microscopy and the in vitro bovine cornea. Eye & contact lens 20071101
Assessment of cell viability in a three-dimensional enzymatically cross-linked collagen scaffold. Journal of materials science. Materials in medicine 20071001
Isobavachalcone, a chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma. Biological & pharmaceutical bulletin 20071001
Characterization of benign and malignant prostate epithelial Hoechst 33342 side populations. The Prostate 20070915
The effects of nickel and chromium on human keratinocytes: differences in viability, cell associated metal and IL-1alpha release. Toxicology in vitro : an international journal published in association with BIBRA 20070801
Mechanism of tert-butylhydroperoxide induced cytotoxicity in U-937 macrophages by alteration of mitochondrial function and generation of ROS. Toxicology in vitro : an international journal published in association with BIBRA 20070801
Limits of propidium iodide as a cell viability indicator for environmental bacteria. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20070801
Apoptotic mode of cell death in substantia nigra following intranigral infusion of the parkinsonian neurotoxin, MPP+ in Sprague-Dawley rats: cellular, molecular and ultrastructural evidences. Neurochemical research 20070701
Cyclophosphamide-induced apoptosis in COV434 human granulosa cells involves oxidative stress and glutathione depletion. Toxicological sciences : an official journal of the Society of Toxicology 20070701
Assessment of epithelial integrity and cell viability in epithelial flaps prepared with the epi-LASIK procedure. Journal of cataract and refractive surgery 20070701
Probing ligand binding to duplex DNA using KMnO4 reactions and electrospray ionization tandem mass spectrometry. Analytical chemistry 20070615
Results from the 'Technical workshop on genotoxicity biosensing' on the micro-scale fluorometric assay of deoxyribonucleic acid unwinding. Analytica chimica acta 20070612
Cholesterol potentiates ABCG2 activity in a heterologous expression system: improved in vitro model to study function of human ABCG2. The Journal of pharmacology and experimental therapeutics 20070601
Effect of lidamycin on telomerase activity in human hepatoma BEL-7402 cells. Biomedical and environmental sciences : BES 20070601
Protein SUMOylation is massively increased in hibernation torpor and is critical for the cytoprotection provided by ischemic preconditioning and hypothermia in SHSY5Y cells. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070501
Cytotoxic activity of gemcitabine and correlation with expression profile of drug-related genes in human lymphoid cells. Pharmacological research 20070401
A new proteasome inhibitor, TP-110, induces apoptosis in human prostate cancer PC-3 cells. Bioscience, biotechnology, and biochemistry 20070401
Involvement of caspase-3, lipid peroxidation and TNF-alpha in causing apoptosis of macrophages by coordinately expressed Salmonella phenotype under stress conditions. Molecular immunology 20070301
Studies on cell-cycle synchronization in the asexual erythrocytic stages of Plasmodium falciparum. Parasitology 20070301
The use of flow cytometry to study the germination of Bacillus cereus endospores. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20070301
Zebrafish kidney marrow contains ABCG2-dependent side population cells exhibiting hematopoietic stem cell properties. Differentiation; research in biological diversity 20070301
Pax6 controls cerebral cortical cell number by regulating exit from the cell cycle and specifies cortical cell identity by a cell autonomous mechanism. Developmental biology 20070201
Using Hoechst 33342 to target radioactivity to the cell nucleus. Radiation research 20070201
[Culture, identification and label of embryonic rat neural stem cells]. Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery 20070201
Chemoprotective effect of insulin-like growth factor I against acetaminophen-induced cell death in Chang liver cells via ERK1/2 activation. Toxicology 20070125
Differential regulation of calcium channel coding genes by prolonged depolarization. Neurochemistry international 20070101
Localized functional chemical stimulation of TE 671 cells cultured on nanoporous membrane by calcein and acetylcholine. Biophysical journal 20070101
Isolation of side population cells from ginbuna carp (Carassius auratus langsdorfii) kidney hematopoietic tissues. Developmental and comparative immunology 20070101
Morphological changes in the hippocampus following nicotine and kainic acid administration. Physiological research 20070101
Caveolin-1 sensitizes rat pituitary adenoma GH3 cells to bromocriptine induced apoptosis. Cancer cell international 20070101
Transplacental murine cytomegalovirus infection in the brain of SCID mice. Virology journal 20070101
Live-cell assay for detection of apoptosis by dual-laser flow cytometry using Hoechst 33342 and 7-amino-actinomycin D. Nature protocols 20070101
LEDGF/p75 has increased expression in blasts from chemotherapy-resistant human acute myelogenic leukemia patients and protects leukemia cells from apoptosis in vitro. Molecular cancer 20070101
A new look at the ventral nerve centre of Sagitta: implications for the phylogenetic position of Chaetognatha (arrow worms) and the evolution of the bilaterian nervous system. Frontiers in zoology 20070101
15d-PGJ2 induces apoptosis of mouse oligodendrocyte precursor cells. Journal of neuroinflammation 20070101
Synthesis and evaluation of intercalating somatostatin receptor binding peptide conjugates for endoradiotherapy. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20070101
Site-specific acetylation of ISWI by GCN5. BMC molecular biology 20070101
The use of propidium iodide to assess excitotoxic neuronal death in primary mixed cortical cultures. Methods in molecular biology (Clifton, N.J.) 20070101
Multiple distinct subtypes of GABAergic neurons in mouse visual cortex identified by triple immunostaining. Frontiers in neuroanatomy 20070101
The role of superoxide anions in the development of distant tumour recurrence. British journal of cancer 20061204
NF-kappaB signaling pathway is involved in growth inhibition, G2/M arrest and apoptosis induced by Trichostatin A in human tongue carcinoma cells. Pharmacological research 20061201
Sensory and sympathetic innervation of cervical facet joint in rats. Chinese journal of traumatology = Zhonghua chuang shang za zhi 20061201
Two membrane proteins from Bifidobacterium breve UCC2003 constitute an ABC-type multidrug transporter. Microbiology (Reading, England) 20061201
Laser scanning cytometry in the characterization of the proapoptotic effects of transiently transfected genes in cerebellar granule neurons. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20061101
Multiple drugbinding sites on the R482G isoform of the ABCG2 transporter. British journal of pharmacology 20061101
Effect of hypoxia on the transcription pattern of subunit isoforms and the kinetics of cytochrome c oxidase in cortical astrocytes and cerebellar neurons. Journal of neurochemistry 20061101
Hypophosphorylation of the architectural chromatin protein DEK in death-receptor-induced apoptosis revealed by the isotope coded protein label proteomic platform. Proteomics 20061101
Impact of 17beta-estradiol on cytokine-mediated apoptotic effects in primary hippocampal and neocortical cell cultures. Brain research 20061020
The effect of hyaluronan concentrations in hST-supplemented TCM 199 on in vitro nuclear maturation of bitch cumulus-oocyte complexes. Theriogenology 20061001
In vitro canine oocyte nuclear maturation in homologous oviductal cell co-culture with hormone-supplemented media. Theriogenology 20061001
The fast halo assay: an improved method to quantify genomic DNA strand breakage at the single-cell level. Mutation research 20060905
Rotenone induces cell death in primary dopaminergic culture by increasing ROS production and inhibiting mitochondrial respiration. Neurochemistry international 20060901
Exit from arsenite-induced mitotic arrest is p53 dependent. Environmental health perspectives 20060901
Protective effects of epoxyeicosatrienoic acids on human endothelial cells from the pulmonary and coronary vasculature. American journal of physiology. Heart and circulatory physiology 20060801
Mechanisms underlying production of double-strand breaks in plasmid DNA after decay of 125I-Hoechst. Radiation research 20060801
Spectral analysis of the DNA targeting bisalkylaminoanthraquinone DRAQ5 in intact living cells. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060801
Antiproliferative and antioxidant properties of an enzymatic hydrolysate from brown alga, Ecklonia cava. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060701
Cell sorting but not serum starvation is effective for SV40 human corneal epithelial cell cycle synchronization. Experimental eye research 20060701
The presence of ABCG2-dependent side population cells in human periodontal ligaments. Biochemical and biophysical research communications 20060616
Cell death effects of resin-based dental material compounds and mercurials in human gingival fibroblasts. Archives of toxicology 20060601
Voltage-dependent potassium channels are involved in glutamate-induced apoptosis of rat hippocampal neurons. Neuroscience letters 20060501
Proteasomal proteolysis in anoxia-reoxygenation, preconditioning and postconditioning of isolated cardiomyocytes. Pathophysiology : the official journal of the International Society for Pathophysiology 20060501
Space asymmetry directs preferential sperm entry in the absence of polarity in the mouse oocyte. PLoS biology 20060501
Zn(II)-phthalocyanines as phototherapeutic agents for cutaneous diseases. Photosensitization of fibroblasts and keratinocytes. Journal of photochemistry and photobiology. B, Biology 20060403
Neuroprotection via inhibition of nitric oxide synthase by bis(7)-tacrine. Neuroreport 20060403
Usefulness of a triple fluorochrome combination Merocyanine 540/Yo-Pro 1/Hoechst 33342 in assessing membrane stability of viable frozen-thawed spermatozoa from Estonian Holstein AI bulls. Theriogenology 20060401
Functional gene cloning and characterization of MdeA, a multidrug efflux pump from Staphylococcus aureus. Biological & pharmaceutical bulletin 20060401
Formation of biofilm at different nutrient levels by various genotypes of Listeria monocytogenes. Journal of food protection 20060401
Out of the blue: a comparison of Hoechst side population (SP) analysis of murine bone marrow using 325, 363 and 407 nm excitation sources. Journal of immunological methods 20060320
Protection of corticospinal tract neurons after dorsal spinal cord transection and engraftment of olfactory ensheathing cells. Glia 20060301
Nucleic acid binding agents exert local toxic effects on neurites via a non-nuclear mechanism. Journal of neurochemistry 20060301
Role of heme oxygenase in the protection afforded skeletal muscle during ischemic tolerance. Microcirculation (New York, N.Y. : 1994) 20060301
Automated four-color analysis of leukocytes by scanning fluorescence microscopy using quantum dots. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060301
Analysis of living S. cerevisiae cell states--a three color approach. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060301
Effect of gonadotrophin stimulation on mouse oocyte quality and subsequent embryonic development in vitro. Reproductive biomedicine online 20060301
Inhibition of apoptosis by p26: implications for small heat shock protein function during Artemia development. Cell stress & chaperones 20060301
Embryotoxicity of the nitric oxide donor sodium nitroprusside in preimplantation bovine embryos in vitro. Animal reproduction science 20060201
Microscopy under pressure--an optical chamber system for fluorescence microscopic analysis of living cells under high hydrostatic pressure. Microscopy research and technique 20060201
Arsenic trioxide induces apoptosis of human monocytes during macrophagic differentiation through nuclear factor-kappaB-related survival pathway down-regulation. The Journal of pharmacology and experimental therapeutics 20060101
Leishmania donovani: differential activities of classical topoisomerase inhibitors and antileishmanials against parasite and host cells at the level of DNA topoisomerase I and in cytotoxicity assays. Experimental parasitology 20060101
A novel subpopulation lacking Oct4 expression in the testicular side population. International journal of molecular medicine 20060101
Melanoma, a tumor based on a mutant stem cell? The Journal of investigative dermatology 20060101
Neuroprotective effects of green and black teas and their catechin gallate esters against beta-amyloid-induced toxicity. The European journal of neuroscience 20060101
Demonstration of hematopoietic stem cells in ginbuna carp (Carassius auratus langsdorfii) kidney. Developmental and comparative immunology 20060101
Impairment of chondrocyte biosynthetic activity by exposure to 3-tesla high-field magnetic resonance imaging is temporary. Arthritis research & therapy 20060101
Proteasome inhibitors eliminate protective effect of postconditioning in cultured neonatal cardiomyocytes. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20060101
Is disturbed clearance of apoptotic keratinocytes responsible for UVB-induced inflammatory skin lesions in systemic lupus erythematosus? Arthritis research & therapy 20060101
Effects of bovine spermatozoa preparation on embryonic development in vitro. Reproductive biology and endocrinology : RB&E 20060101
Cytotoxicity of different selective serotonin reuptake inhibitors (SSRIs) against cancer cells. Journal of experimental therapeutics & oncology 20060101
Proton motive force-dependent Hoechst 33342 transport by the ABC transporter LmrA of Lactococcus lactis. Biochemistry 20051227
Accumulation of DNA, nuclear and mitochondrial debris, and ROS at sites of age-related cortical cataract in mice. Investigative ophthalmology & visual science 20051201
Effect of NMDA on staurosporine-induced activation of caspase-3 and LDH release in mouse neocortical and hippocampal cells. Brain research. Developmental brain research 20051107
The Q-loop disengages from the first intracellular loop during the catalytic cycle of the multidrug ABC transporter BmrA. The Journal of biological chemistry 20051104
Reactive oxygen species-mediated beta-cleavage of the prion protein in the cellular response to oxidative stress. The Journal of biological chemistry 20051028
Influence of initial charge state on fragmentation patterns for noncovalent drug/DNA duplex complexes. Journal of mass spectrometry : JMS 20051001
Neuroprotective effects of minocycline against in vitro and in vivo retinal ganglion cell damage. Brain research 20050816
Fully grown mouse oocyte contains transcription inhibiting activity which acts through histone deacetylation. Molecular reproduction and development 20050801
IB1/JIP-1 controls JNK activation and increased during prostatic LNCaP cells neuroendocrine differentiation. Cellular signalling 20050801
Comparison of different methods of CAIX quantification in relation to hypoxia in three human head and neck tumor lines. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20050801
Quantitative cell-based high-content screening for vasopressin receptor agonists using transfluor technology. Journal of biomolecular screening 20050801
Resistance mechanism development to the topoisomerase-I inhibitor Hoechst 33342 by Leishmania donovani. Parasitology 20050801
Hypoxic cell turnover in different solid tumor lines. International journal of radiation oncology, biology, physics 20050715
Thymidine analogues to assess microperfusion in human tumors. International journal of radiation oncology, biology, physics 20050715
Change in mitochondrial membrane potential is the key mechanism in early warm hepatic ischemia-reperfusion injury. Microvascular research 20050701
Effect of staining and sorting on boar sperm membrane integrity, mitochondrial activity and in vitro blastocyst development. Theriogenology 20050701
Increased functional expression of P-glycoprotein in Caco-2 TC7 cells exposed long-term to cadmium. Toxicology in vitro : an international journal published in association with BIBRA 20050601
Cytotoxic effects of 110 reference compounds on HepG2 cells and for 60 compounds on HeLa, ECC-1 and CHO cells. II mechanistic assays on NAD(P)H, ATP and DNA contents. Toxicology in vitro : an international journal published in association with BIBRA 20050601
Dependence of FDG uptake on tumor microenvironment. International journal of radiation oncology, biology, physics 20050601
Flavonoid structure-activity studies identify 6-prenylchrysin and tectochrysin as potent and specific inhibitors of breast cancer resistance protein ABCG2. Cancer research 20050601
Immunosuppressive immunophilin ligands attenuate damage in cultured rat astrocytes depleted of glutathione and exposed to simulated ischemia in vitro. Comparison with N-acetylcysteine. Neurotoxicology 20050601
Prediction of genotoxicity of chemical compounds by statistical learning methods. Chemical research in toxicology 20050601
Minocycline inhibits oxidative stress and decreases in vitro and in vivo ischemic neuronal damage. Brain research 20050517
The effect of quercetin on pro-apoptotic activity of cisplatin in HeLa cells. Biochemical pharmacology 20050501
Differences in the incidence of apoptosis between in vivo and in vitro produced blastocysts of farm animal species: a comparative study. Theriogenology 20050501
Construction of an electrochemical DNA chip for simultaneous genotyping of single nucleotide polymorphisms. The Analyst 20050501
[Evaluation of the survival of bone marrow mononucleate cells transplanted in a rat model of striatal lesion with quinolinic acid]. Revista de neurologia 20050501
Protective effects of Delta(9)-tetrahydrocannabinol against N-methyl-d-aspartate-induced AF5 cell death. Brain research. Molecular brain research 20050404
The DNA minor groove binding agents Hoechst 33258 and 33342 enhance recombinant adeno-associated virus (rAAV) transgene expression. The journal of gene medicine 20050401
7-Ketocholesterol favors lipid accumulation and colocalizes with Nile Red positive cytoplasmic structures formed during 7-ketocholesterol-induced apoptosis: analysis by flow cytometry, FRET biphoton spectral imaging microscopy, and subcellular fractionation. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20050401
Protection by exogenous pyruvate through a mechanism related to monocarboxylate transporters against cell death induced by hydrogen peroxide in cultured rat cortical neurons. Journal of neurochemistry 20050401
Assessment of regional tumor hypoxia using 18F-fluoromisonidazole and 64Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone) positron emission tomography: Comparative study featuring microPET imaging, Po2 probe measurement, autoradiography, and fluorescent microscopy in the R3327-AT and FaDu rat tumor models. International journal of radiation oncology, biology, physics 20050401
NF-kappaB pathway protects cochlear hair cells from aminoglycoside-induced ototoxicity. Journal of neuroscience research 20050301
Interaction between gemcitabine and topotecan in human non-small-cell lung cancer cells: effects on cell survival, cell cycle and pharmacogenetic profile. British journal of cancer 20050227
Function-dependent conformational changes of the ABCG2 multidrug transporter modify its interaction with a monoclonal antibody on the cell surface. The Journal of biological chemistry 20050211
In vivo characterization of developing chronic pancreatitis in rats. Laboratory investigation; a journal of technical methods and pathology 20050201
Development of an ischemic tolerance model in a PC12 cell line. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20050201
Single amino acid (482) variants of the ABCG2 multidrug transporter: major differences in transport capacity and substrate recognition. Biochimica et biophysica acta 20050201
[Comparison between two methods for staining DNA of apoptotic spermatozoa]. Zhonghua nan ke xue = National journal of andrology 20050201
Pro-apoptotic effects of the flavonoid luteolin in rat H4IIE cells. Toxicology 20050131
Pro- and anti-apoptotic roles of c-Jun N-terminal kinase (JNK) in ethanol and acetaldehyde exposed rat hepatocytes. European journal of pharmacology 20050131
Flow cytometric evaluation of sperm parameters in relation to fertility potential. Theriogenology 20050115
Cross-talk between phosphatidic acid and ceramide during ethanol-induced apoptosis in astrocytes. BMC pharmacology 20050101
Electrostatic trapping of double-stranded DNA by using cadmium hydroxide nanostrands. Nano letters 20050101
Effect of three vitrification methods on development of two-cell mouse embryos. Cryo letters 20050101
Flow cytometric monitoring of fluorescent drug retention and efflux. Methods in molecular medicine 20050101
Characterization and localization of side population cells in mouse skin. Stem cells (Dayton, Ohio) 20050101
Single UV excitation of Hoechst 33342 and propidium iodide for viability assessment of rhesus monkey spermatozoa using flow cytometry. Archives of andrology 20050101
Potential protective effects of NSAIDs/ASA in oxidatively stressed human lens epithelial cells and intact mouse lenses in culture. Ophthalmic research 20050101
Bone marrow stromal cells increase astrocyte survival via upregulation of phosphoinositide 3-kinase/threonine protein kinase and mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathways and stimulate astrocyte trophic factor gene expression after anaerobic insult. Neuroscience 20050101
ROS-mediated genotoxicity of asbestos-cement in mammalian lung cells in vitro. Particle and fibre toxicology 20050101
Use of three-dimensional collagen gels to study mechanotransduction in T47D breast epithelial cells. Biological procedures online 20050101
An improved definition of mouse mammary epithelial side population cells. Cytotherapy 20050101
Heterogeneity in the radiosensitizing effects of the DNA ligand hoechst-33342 in human tumor cell lines. Journal of cancer research and therapeutics 20050101
Mitochondrial targeting sequence of the influenza A virus PB1-F2 protein and its function in mitochondria. FEBS letters 20041217
DNA ligand Hoechst-33342 enhances UV induced cytotoxicity in human glioma cell lines. Journal of photochemistry and photobiology. B, Biology 20041202
[Biocompatibilty of silicon nitride ceramic in vitro. A comparative fluorescence-microscopic and scanning electron-microscopic study]. Laryngo- rhino- otologie 20041201
Histone H2AX phosphorylation induced by selective photolysis of BrdU-labeled DNA with UV light: relation to cell cycle phase. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20041101
Khat (Catha edulis)-induced apoptosis is inhibited by antagonists of caspase-1 and -8 in human leukaemia cells. British journal of cancer 20041101
Differential staining of DNA and RNA. Current protocols in cytometry 20041101
Energetics of wild-type and mutant multidrug resistance secondary transporter LmrP of Lactococcus lactis. Biochimica et biophysica acta 20041004
Biological responses in known bystander cells relative to known microbeam-irradiated cells. Radiation research 20041001
Celastraceae sesquiterpenes as a new class of modulators that bind specifically to human P-glycoprotein and reverse cellular multidrug resistance. Cancer research 20041001
Comparative investigation of the biocompatibility of various silicon nitride ceramic qualities in vitro. Journal of materials science. Materials in medicine 20041001
Proton motive force mediates a reorientation of the cytosolic domains of the multidrug transporter LmrP. Cellular and molecular life sciences : CMLS 20041001
Inhibition of Leishmania donovani promastigote DNA topoisomerase I and human monocyte DNA topoisomerases I and II by antimonial drugs and classical antitopoisomerase agents. The Journal of parasitology 20041001
A new human breast carcinoma cell line resistant to DNA-damaging drugs. Alternatives to laboratory animals : ATLA 20041001
Inhibition of amyloid-beta-induced neurotoxicity and apoptosis by moderate ethanol preconditioning. Neuroreport 20040915
Ciglitizone and 15d PGJ2 induce apoptosis in Jurkat and Raji cells. International immunopharmacology 20040901
2-deoxy-D-glucose enhances the cytotoxicity of topoisomerase inhibitors in human tumor cell lines. Cancer biology & therapy 20040901
The remyelinating potential and in vitro differentiation of MOG-expressing oligodendrocyte precursors isolated from the adult rat CNS. The European journal of neuroscience 20040901
Effect of beta-mercaptoethanol or epidermal growth factor supplementation on in vitro maturation of canine oocytes collected from dogs with different stages of the estrus cycle. Journal of veterinary science 20040901
Development of neural stem/progenitor cells from human brain by transplantation into the brains of adult rats. Neuroscience and behavioral physiology 20040901
Effect of inhibiting nitric oxide production on mouse preimplantation embryo development and metabolism. Biology of reproduction 20040801
Hypoxia and Photofrin uptake in the intraperitoneal carcinomatosis and sarcomatosis of photodynamic therapy patients. Clinical cancer research : an official journal of the American Association for Cancer Research 20040715
Retinal microvascular patency in the diabetic rat. International ophthalmology 20040701
Erk1/2 and Akt kinases are involved in the protective effect of aniracetam in astrocytes subjected to simulated ischemia in vitro. European journal of pharmacology 20040628
Cannabinoid CB1 receptor protein expression in the rat choroid plexus: a possible involvement of cannabinoids in the regulation of cerebrospinal fluid. Neuroscience letters 20040624
ABC transporter activities of murine hematopoietic stem cells vary according to their developmental and activation status. Blood 20040615
Characterization of YvcC (BmrA), a multidrug ABC transporter constitutively expressed in Bacillus subtilis. Biochemistry 20040615
The apoptotic and necrotic effects of tomatine adjuvant. Vaccine 20040602
Auranofin induces apoptosis and when combined with retinoic acid enhances differentiation of acute promyelocytic leukaemia cells in vitro. British journal of pharmacology 20040601
DFNA5: hearing impairment exon instead of hearing impairment gene? Journal of medical genetics 20040601
In vitro assessment of the efficacy of thermal therapy in human benign prostatic hyperplasia. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 20040601
Human limbal epithelium contains side population cells expressing the ATP-binding cassette transporter ABCG2. FEBS letters 20040507
Differentiation-dependent photodynamic therapy regulated by porphobilinogen deaminase in B16 melanoma. British journal of cancer 20040504
Genotoxic and antiapoptotic effect of nicotine on human gingival fibroblasts. Toxicological sciences : an official journal of the Society of Toxicology 20040501
Hematopoietic and nonhematopoietic potentials of Hoechst(low)/side population cells isolated from adult rat kidney. Kidney international 20040501
Evidence of tubular hypoxia in the early phase in the remnant kidney model. Journal of the American Society of Nephrology : JASN 20040501
Stage-specific effect of N-(4-hydroxyphenyl)retinamide on cell growth in squamous cell carcinogenesis. Molecular carcinogenesis 20040501
Differential regulation of the mitochondrial and death receptor pathways in neural stem cells. The European journal of neuroscience 20040501
Among circulating hematopoietic cells, B-CLL uniquely expresses functional EPAC1, but EPAC1-mediated Rap1 activation does not account for PDE4 inhibitor-induced apoptosis. Blood 20040401
Mechanisms of coxsackievirus B5 mediated beta-cell death depend on the multiplicity of infection. Journal of medical virology 20040401
Amplification of nuclear aldolase A in mouse cell mutants resistant to Hoechst 33342. Biochemical and biophysical research communications 20040319
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies. Biochemical and biophysical research communications 20040319
Irradiation attenuates neurogenesis and exacerbates ischemia-induced deficits. Annals of neurology 20040301
Hoechst 33342 is a useful cell tracer for a long-term investigation of articular cartilage repair. Archives of histology and cytology 20040301
Inhibitory effect of IGF-I on induced apoptosis in mouse preimplantation embryos cultured in vitro. Theriogenology 20040201
Frequency of M-cadherin-stained satellite cells declines in human muscles during aging. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20040201
Analysis of the fluorescence of monodansylcadaverine-positive cytoplasmic structures during 7-ketocholesterol-induced cell death. Analytical and quantitative cytology and histology 20040201
Optimization of an Acridine Orange-bisbenzimide procedure for the detection of apoptosis-associated fluorescence colour changes in etoposide-treated cell cultures. Journal of molecular histology 20040201
Modulation of ATP levels alters the mode of hydrogen peroxide-induced cell death in primary cortical cultures: effects of putative neuroprotective agents. Brain research 20040130
Overexpression of superoxide dismutase 1 protects against beta-amyloid peptide toxicity: effect of estrogen and copper chelators. Neurochemistry international 20040101
Bioassay using epidermal keratinocytes to determine phosphorylation status of the epidermal growth factor receptor in distant neoplasms. International journal of oncology 20040101
The chemokine receptor CXCR4 and not the N-methyl-D-aspartate receptor mediates gp120 neurotoxicity in cerebellar granule cells. Journal of neuroscience research 20040101
Expression of a novel gene, gluP, is essential for normal Bacillus subtilis cell division and contributes to glucose export. BMC microbiology 20040101
Collagen production in cardiac fibroblasts during inhibition of angiotensin-converting enzyme and aminopeptidases. Journal of hypertension 20040101
ATF3 upregulation in glia during Wallerian degeneration: differential expression in peripheral nerves and CNS white matter. BMC neuroscience 20040101
Cumulus expansion, nuclear maturation and connexin 43, cyclooxygenase-2 and FSH receptor mRNA expression in equine cumulus-oocyte complexes cultured in vitro in the presence of FSH and precursors for hyaluronic acid synthesis. Reproductive biology and endocrinology : RB&E 20040101
Enrichment and characterization of mouse putative epidermal stem cells. Cell biology international 20040101
Selected cyclic dipeptides inhibit cancer cell growth and induce apoptosis in HT-29 colon cancer cells. Anticancer research 20040101
High-resolution image cytometry of rat sperm nuclear shape, size and chromatin status. Experimental validation with the reproductive toxicant vinclozolin. Reproductive toxicology (Elmsford, N.Y.) 20040101
Mitochondrial membrane potential change induced by Hoechst 33342 in myelogenous leukemia cell line HL-60. Annals of clinical and laboratory science 20040101
Methanethiosulfonate derivatives of rhodamine and verapamil activate human P-glycoprotein at different sites. The Journal of biological chemistry 20031212
Minor groove binding DNA ligands with expanded A/T sequence length recognition, selective binding to bent DNA regions and enhanced fluorescent properties. Biochemistry 20031118
Glial cells maintain synaptic structure and function and promote development of the neuromuscular junction in vivo. Neuron 20031030
Akt signaling regulates side population cell phenotype via Bcrp1 translocation. The Journal of biological chemistry 20031003
Phenotype and hematopoietic potential of side population cells throughout embryonic development. Blood 20031001
Inhibition of signal transduction in EGF-dependent epithelial cell lines. International journal of molecular medicine 20031001
Fission yeast Sap1 protein is essential for chromosome stability. Eukaryotic cell 20031001
Elimination of serotonergic cells induces a marked increase in generation of dopaminergic neurons from mesencephalic precursors. The European journal of neuroscience 20031001
Gamma-irradiation enhances apoptosis induced by cannabidiol, a non-psychotropic cannabinoid, in cultured HL-60 myeloblastic leukemia cells. Leukemia & lymphoma 20031001
Induced cell death of preimplantation mouse embryos cultured in vitro evaluated by comet assay. Theriogenology 20030901
Hoechst 33342 alters luciferase gene expression in transfected BC3H-1 myocytes. Archives of pathology & laboratory medicine 20030901
Caspase-3 dependent proteolytic activation of protein kinase C delta mediates and regulates 1-methyl-4-phenylpyridinium (MPP+)-induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration. The European journal of neuroscience 20030901
Influence of phenyl ring disubstitution on bisbenzimidazole and terbenzimidazole cytotoxicity: synthesis and biological evaluation as radioprotectors. Journal of medicinal chemistry 20030828
1alpha,25-dihydroxyvitamin D(3) (calcitriol) and its analogue, 19-nor-1alpha,25(OH)(2)D(2), potentiate the effects of ionising radiation on human prostate cancer cells. British journal of cancer 20030818
Retrograde transport of sodium selenite and intracellular injection of micro-ruby: a combined method to describe the morphology of zinc-rich neurones. Journal of neuroscience methods 20030815
Effects of overexpression of dimethylarginine dimethylaminohydrolase on tumor angiogenesis assessed by susceptibility magnetic resonance imaging. Cancer research 20030815
Carboxylesterase-mediated sensitization of human tumor cells to CPT-11 cannot override ABCG2-mediated drug resistance. Molecular pharmacology 20030801
Novel method for the isolation and characterisation of the putative prostatic stem cell. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20030801
The varicella-zoster virus induces apoptosis in vitro in subpopulations of primary human peripheral blood mononuclear cells. Microbes and infection 20030801
Reversal of Bcl-2-mediated resistance of the EW36 human B-cell lymphoma cell line to arsenite- and pesticide-induced apoptosis by PK11195, a ligand of the mitochondrial benzodiazepine receptor. Toxicological sciences : an official journal of the Society of Toxicology 20030701
Hepatic oval cells have the side population phenotype defined by expression of ATP-binding cassette transporter ABCG2/BCRP1. The American journal of pathology 20030701
MAPK is involved in metaphase I arrest in oyster and mussel oocytes. Biology of the cell 20030701
Sterol transport by the human breast cancer resistance protein (ABCG2) expressed in Lactococcus lactis. The Journal of biological chemistry 20030606
Cigarette smoke extract induces oxidative stress and apoptosis in human lung fibroblasts. American journal of physiology. Lung cellular and molecular physiology 20030601
Sanguinarine-induced apoptosis is associated with an early and severe cellular glutathione depletion. Cancer chemotherapy and pharmacology 20030601
Sensitization by interleukin-6 of rat hepatocytes to tumor necrosis factor alpha-induced apoptosis. Journal of hepatology 20030601
Direct identification and enrichment of retinal stem cells/progenitors by Hoechst dye efflux assay. Investigative ophthalmology & visual science 20030601
Hsp70 prevents nitric oxide-induced apoptosis in articular chondrocytes. Arthritis and rheumatism 20030601
Effect of nitric oxide on the proliferation of cultured porcine trabecular meshwork cells. Korean journal of ophthalmology : KJO 20030601
Dual fluorescence analysis of DNA apoptosis in sperm. American journal of obstetrics and gynecology 20030501
Effects of the proapoptotic drug prodigiosin on cell cycle-related proteins in Jurkat T cells. Histology and histopathology 20030401
Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites. Pharmaceutical research 20030401
Use of the confocal laser scanning microscope in studies on the developmental biology of marine crustaceans. Microscopy research and technique 20030301
Quantitative fluorescence imaging approach for the study of polyploidization in hepatocytes. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20030301
Migration of cochlear lateral wall cells. Hearing research 20030301
Colchicine induces apoptosis in organotypic hippocampal slice cultures. Brain research 20030227
Transition state P-glycoprotein binds drugs and modulators with unchanged affinity, suggesting a concerted transport mechanism. Biochemistry 20030211
Functional and molecular characterisation of mammary side population cells. Breast cancer research : BCR 20030101
Limitations of ischemic tolerance in oxidative skeletal muscle: perfusion vs tissue protection. The Journal of surgical research 20030101
Oxidative stress causes ERK phosphorylation and cell death in cultured retinal pigment epithelium: prevention of cell death by AG126 and 15-deoxy-delta 12, 14-PGJ2. BMC ophthalmology 20030101
Flow cytometric analysis of cell cycle control by tumor suppressor genes. Methods in molecular biology (Clifton, N.J.) 20030101
Mode of cell death induced in Chinese hamster cells by sequence-selective DNA minor groove binding nitrogen mustards: comparison with untargeted mustards and with Hoechst 33342. Oncology research 20030101
Microglial cell death induced by a low concentration of polyamines. Neuroscience 20030101
IGF-1/IGFBP-1 increases blastocyst formation and total blastocyst cell number in mouse embryo culture and facilitates the establishment of a stem-cell line. BMC cell biology 20030101
HaCaT cell proliferation influenced by melatonin. Skin pharmacology and applied skin physiology 20030101
Creating genetically modified pigs by using nuclear transfer. Reproductive biology and endocrinology : RB&E 20030101
In vitro and in vivo assessment of functional capacity of flow cytometrically sorted ram spermatozoa after freezing and thawing. Reproduction, fertility, and development 20030101
Characterization of drug transport, ATP hydrolysis, and nucleotide trapping by the human ABCG2 multidrug transporter. Modulation of substrate specificity by a point mutation. The Journal of biological chemistry 20021213
Apoptosis: biochemical aspects and clinical implications. Clinica chimica acta; international journal of clinical chemistry 20021201
The development of combretastatin A4 phosphate as a vascular targeting agent. International journal of radiation oncology, biology, physics 20021201
Enhancement of vascular targeting by inhibitors of nitric oxide synthase. International journal of radiation oncology, biology, physics 20021201
Neuronal uptake of pesticides disrupts chemosensory cells of nematodes. Parasitology 20021201
3,4-Methylenedioxymethamphetamine ('Ecstasy') induces apoptosis of cultured rat liver cells. Biochimica et biophysica acta 20021009
Low density lipoprotein can cause death of islet beta-cells by its cellular uptake and oxidative modification. Endocrinology 20020901
Purinergic and muscarinic modulation of the cell cycle and calcium signaling in the chick retinal ventricular zone. The Journal of neuroscience : the official journal of the Society for Neuroscience 20020901
Roles of endogenous glutathione levels on 6-hydroxydopamine-induced apoptotic neuronal cell death in human neuroblastoma SK-N-SH cells. Neuropharmacology 20020901
Heat shock inhibits hydrogen peroxide-induced apoptosis in cultured astrocytes. Brain research 20020816
Evidence that ultrafine titanium dioxide induces micronuclei and apoptosis in Syrian hamster embryo fibroblasts. Environmental health perspectives 20020801
Liver and marrow of adult mdr-1a/1b(-/-) mice show normal generation, function, and multi-tissue trafficking of primitive hematopoietic cells. Experimental hematology 20020801
Helicobacter pylori prevents proliferative stage of angiogenesis in vitro: role of cytokines. Digestive diseases and sciences 20020801
Effect of Hoechst 33342 staining on developmental competence of prepubertal goat oocytes. Zygote (Cambridge, England) 20020801
Acidic residues in the lactococcal multidrug efflux pump LmrP play critical roles in transport of lipophilic cationic compounds. The Journal of biological chemistry 20020719
PTK787/ZK 222584, a specific vascular endothelial growth factor-receptor tyrosine kinase inhibitor, affects the anatomy of the tumor vascular bed and the functional vascular properties as detected by dynamic enhanced magnetic resonance imaging. Cancer research 20020715
Nuclear shrinkage and other markers of neuronal cell death after oxygen-glucose deprivation in rat hippocampal slice cultures. Neuroscience letters 20020712
Ceramide accumulation is independent of camptothecin-induced apoptosis in prostate cancer LNCaP cells. Biochemical and biophysical research communications 20020607
Activity of the GR in G2 and mitosis. Molecular endocrinology (Baltimore, Md.) 20020601
Oxidative stress mediates cell surface expression of SS-A/Ro antigen on keratinocytes. Free radical biology & medicine 20020515
A novel flow cytometric technique for drug cytotoxicity gives results comparable to colony-forming assays. Cytometry 20020501
Parthenogenesis of rabbit oocytes activated by different stimuli. Animal reproduction science 20020415
Comparative genomic hybridization analysis of sperm DNA apoptosis after exposure to heat shock. Journal of assisted reproduction and genetics 20020401
Behavior of human neural progenitor cells transplanted to rat brain. Brain research. Developmental brain research 20020331
Effects of immunophilin ligands on hydrogen peroxide-induced apoptosis in C6 glioma cells. Synapse (New York, N.Y.) 20020301
Structural and functional asymmetry of the nucleotide-binding domains of P-glycoprotein investigated by attenuated total reflection Fourier transform infrared spectroscopy. The Journal of biological chemistry 20020215
Local hypoxia is produced at sites of intratumour injection. British journal of cancer 20020201
Microplate screening of the differential effects of test agents on Hoechst 33342, rhodamine 123, and rhodamine 6G accumulation in breast cancer cells that overexpress P-glycoprotein. Journal of biomolecular screening 20020201
The analysis of chromatin organisation allows selection of mouse antral oocytes competent for development to blastocyst. Zygote (Cambridge, England) 20020201
Lack of correlation between AT frequency and genome size in higher plants and the effect of nonrandomness of base sequences on dye binding. Cytometry 20020101
The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells. Clinical cancer research : an official journal of the American Association for Cancer Research 20020101
The farnesyl transferase inhibitor RPR-130401 does not alter radiation susceptibility in human tumor cells with a K-Ras mutation in spite of large changes in ploidy and lamin B distribution. BMC pharmacology 20020101
Activity of the vascular targeting agent combretastatin A-4 disodium phosphate in a xenograft model of AIDS-associated Kaposi's sarcoma. Acta oncologica (Stockholm, Sweden) 20020101
[A cross drug resistance of mammalian cells with a high efficiency of 'DNA clearing']. Tsitologiia 20020101
Mitogen-activated protein kinase inhibitor, PD98059, inhibits rat retinal pigment epithelial cell replication by cell cycle arrest. Japanese journal of ophthalmology 20020101
Neuronal apoptosis inhibitory protein expression after traumatic brain injury in the mouse. Journal of neurotrauma 20011201
Effect of ischemia-reperfusion injury on the microcirculation of the steatotic liver of the Zucker rat. Transplantation 20011127
Tris-benzimidazole derivatives: design, synthesis and DNA sequence recognition. Bioorganic & medicinal chemistry 20011101
Assessment of apoptosis and necrosis by DNA fragmentation and morphological criteria. Current protocols in cell biology 20011101
Evidence for simultaneous binding of dissimilar substrates by the Escherichia coli multidrug transporter MdfA. Biochemistry 20011023
Distribution of P2X receptors on astrocytes in juvenile rat hippocampus. Glia 20011001
Effects of acute and chronic doses of methoxy acetic acid on hamster sperm fertilising ability. Asian journal of andrology 20010901
A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid leukemia. Blood 20010815
A novel photosensitizer, 2-butylamino-2-demethoxy-hypocrellin B (2-BA-2-DMHB) - its photodynamic effects on HeLa cells: efficacy and apoptosis. Biochimica et biophysica acta 20010725
Photophysical properties of fluorescent DNA-dyes bound to single- and double-stranded DNA in aqueous buffered solution. Photochemistry and photobiology 20010601
Perforin and granzyme B induce apoptosis in FasL-resistant colon carcinoma cells. Cancer immunology, immunotherapy : CII 20010601
Double-stranded DNA binding characteristics and subcellular distribution of a minor groove binding diphenyl ether bisbenzimidazole. Biochemistry 20010529
Transfection of annexin 1 in monocytic cells produces a high degree of spontaneous and stimulated apoptosis associated with caspase-3 activation. British journal of pharmacology 20010501
Nuclear shrinkage in live mouse hippocampal slices. Acta neuropathologica 20010501
Determining cell cycle stages by flow cytometry. Current protocols in cell biology 20010501
Role of leukocyte accumulation and oxygen radicals in ischemia-reperfusion-induced injury in skeletal muscle. American journal of physiology. Heart and circulatory physiology 20010401
Transcriptional regulation of topoisomerase II alpha at confluence and pharmacological modulation of expression by bis-benzimidazole drugs. Molecular pharmacology 20010401
Alteration of argyrophilic nucleolar organizer region associated (Ag-NOR) proteins in apoptosis-induced human salivary gland cells and human oral squamous carcinoma cells. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20010401
Direct and sensitized photoprocesses of bis-benzimidazole dyes and the effects of surfactants and DNA. Photochemistry and photobiology 20010401
Hoechst 33342-induced apoptosis is associated with decreased immunoreactive topoisomerase I and topoisomerase I-DNA complex formation. Annals of clinical and laboratory science 20010401
Fixation and permanent mounting of fluorescent probes after vital labelling of cultured cells. Acta histochemica 20010401
Inhibition of P-glycoprotein transport function by grapefruit juice psoralen. Pharmaceutical research 20010401
Prodigiosin-induced apoptosis in human colon cancer cells. Life sciences 20010316
Apoptosis induced by peste des petits ruminants virus in goat peripheral blood mononuclear cells. Virus research 20010301
Fluorescent dyes for cell viability: an application on prefixed conditions. Histochemistry and cell biology 20010301
Isolating a pure population of epidermal stem cells for use in tissue engineering. Experimental dermatology 20010201
Cryopreservation of equine embryos by open pulled straw, cryoloop, or conventional slow cooling methods. Theriogenology 20010115
Successful in vitro production of embryos in the red deer (Cervus elaphus) and the sika deer (Cervus nippon). Theriogenology 20010115
Flow cytometry of erythropoiesis in culture: bivariate profiles of fetal and adult hemoglobin. Methods in cell biology 20010101
Cytometry of antitumor drug-intracellular target interactions. Methods in cell biology 20010101
Resistance of tumor cells to chemo- and radiotherapy modulated by the three-dimensional architecture of solid tumors and spheroids. Methods in cell biology 20010101
Hoechst 33342-induced apoptosis is associated with intracellular accumulation of E2F-1 protein in BC3H-1 myocytes and HL-60 cells. Archives of pathology & laboratory medicine 20010101
Hypothermia prevents hearing loss and progressive hair cell loss after transient cochlear ischemia in gerbils. Neuroscience 20010101
Effects of genotypically different strains of Helicobacter pylori on human microvascular endothelial cells in vitro. Digestive diseases and sciences 20010101
Caspase-3 activity and carbonyl cyanide m-chlorophenylhydrazone-induced apoptosis in HL-60. Alternatives to laboratory animals : ATLA 20010101
Impact of proliferative activity and tumorigenic conversion on mitochondrial function of fibroblasts in 2D and 3D culture. Cell biology international 20010101
Peroxisome proliferator-activated receptor agonists prevent 25-OH-cholesterol induced c-jun activation and cell death. BMC pharmacology 20010101
Lens epithelial cell protection by aminothiol WR-1065 and anetholedithiolethione from ionizing radiation. International journal of cancer 20010101
Induction of apoptosis by remoxipride metabolites in HL60 and CD34+/CD19- human bone marrow progenitor cells: potential relevance to remoxipride-induced aplastic anemia. Chemico-biological interactions 19990801

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