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23142-01-0 | Cyclopentanecarboxylic acid, 1-phenyl-, 2-[2-(diethylamino)ethoxy]ethyl ester, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
CAS No: 23142-01-0 Catalog No: AG002MBZ MDL No:MFCD00055697
Product Description
Catalog Number:
AG002MBZ
Chemical Name:
Cyclopentanecarboxylic acid, 1-phenyl-, 2-[2-(diethylamino)ethoxy]ethyl ester, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
CAS Number:
23142-01-0
Molecular Formula:
C26H39NO10
Molecular Weight:
525.5886
MDL Number:
MFCD00055697
IUPAC Name:
2-[2-(diethylamino)ethoxy]ethyl 1-phenylcyclopentane-1-carboxylate;2-hydroxypropane-1,2,3-tricarboxylic acid
InChI:
InChI=1S/C20H31NO3.C6H8O7/c1-3-21(4-2)14-15-23-16-17-24-19(22)20(12-8-9-13-20)18-10-6-5-7-11-18;7-3(8)1-6(13,5(11)12)2-4(9)10/h5-7,10-11H,3-4,8-9,12-17H2,1-2H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
InChI Key:
AKJDEXBCRLOVTH-UHFFFAOYSA-N
SMILES:
OC(=O)C(CC(=O)O)(CC(=O)O)O.CCN(CCOCCOC(=O)C1(CCCC1)c1ccccc1)CC
EC Number:
245-449-5
UNII:
4SH0MFJ5HJ
NSC Number:
757833
RTECS Number:
GY3500000
Properties
Complexity:
583
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
525.257g/mol
Formal Charge:
0
Heavy Atom Count:
37
Hydrogen Bond Acceptor Count:
11
Hydrogen Bond Donor Count:
4
Isotope Atom Count:
0
Molecular Weight:
525.595g/mol
Monoisotopic Mass:
525.257g/mol
Rotatable Bond Count:
16
Topological Polar Surface Area:
171A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
| Title | Journal |
|---|---|
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| Characterization of pentoxyverine metabolites in urine using GC/MS after intoxication with Silomat cough drops. | Forensic science international 20120210 |
| Cutaneous analgesia and systemic toxicity of carbetapentane and caramiphen in rats. | Regional anesthesia and pain medicine 20120101 |
| Simultaneous determination of potassium guaiacolsulfonate, guaifenesin, diphenhydramine HCl and carbetapentane citrate in syrups by using HPLC-DAD coupled with partial least squares multivariate calibration. | Talanta 20110215 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
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| [Quantification of pentoxyverine citrate in human plasma by LC-ESI/MS method and its application]. | Yao xue xue bao = Acta pharmaceutica Sinica 20091201 |
| Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. | Nature chemical biology 20091001 |
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| Effects of common antitussive drugs on the hERG potassium channel current. | Journal of cardiovascular pharmacology 20081201 |
| sigma-1 receptor modulation of acid-sensing ion channel a (ASIC1a) and ASIC1a-induced Ca2+ influx in rat cortical neurons. | The Journal of pharmacology and experimental therapeutics 20081101 |
| Activation of the spinal sigma-1 receptor enhances NMDA-induced pain via PKC- and PKA-dependent phosphorylation of the NR1 subunit in mice. | British journal of pharmacology 20080701 |
| Sigma-1 receptor activation prevents intracellular calcium dysregulation in cortical neurons during in vitro ischemia. | The Journal of pharmacology and experimental therapeutics 20061201 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Synthesis and in vitro evaluation of iodinated derivatives of piperazine as a new ligand for sigma receptor imaging by single photon emission computed tomography. | Chemical & pharmaceutical bulletin 20060401 |
| Study on the enhancement of Ru(bpy)3(2+) electrochemiluminescence by nanogold and its application for pentoxyverine detection. | Electrophoresis 20051201 |
| Retinal bipolar cell input mechanisms in giant danio. I. Electroretinographic analysis. | Journal of neurophysiology 20050101 |
| Antagonism of NMDA receptors by sigma receptor ligands attenuates chemical ischemia-induced neuronal death in vitro. | European journal of pharmacology 20021129 |
| Spreading depression: imaging and blockade in the rat neocortical brain slice. | Journal of neurophysiology 20021101 |
| A non-potentiometric sensing method for the determination of pentoxyverine with PQC sensors based on ion-pair complexes. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20011201 |
| Carbetapentane attenuates kainate-induced seizures via sigma-1 receptor modulation. | Life sciences 20010713 |
| Propiverine-induced Parkinsonism: a case report and a pharmacokinetic/pharmacodynamic study in mice. | Pharmaceutical research 20000501 |
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