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230-17-1 | BENZO[C]CINNOLINE
CAS No: 230-17-1 Catalog No: AG002LTY MDL No:MFCD00004990
Product Description
Catalog Number:
AG002LTY
Chemical Name:
BENZO[C]CINNOLINE
CAS Number:
230-17-1
Molecular Formula:
C12H8N2
Molecular Weight:
180.2053
MDL Number:
MFCD00004990
IUPAC Name:
benzo[c]cinnoline
InChI:
InChI=1S/C12H8N2/c1-3-7-11-9(5-1)10-6-2-4-8-12(10)14-13-11/h1-8H
InChI Key:
SWJXWSAKHXBQSY-UHFFFAOYSA-N
SMILES:
c1ccc2c(c1)c1ccccc1nn2
EC Number:
205-936-5
UNII:
P346MC4QRL
NSC Number:
86935
Properties
Complexity:
183
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
180.069g/mol
Formal Charge:
0
Heavy Atom Count:
14
Hydrogen Bond Acceptor Count:
2
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
180.21g/mol
Monoisotopic Mass:
180.069g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
25.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.4
Literature
| Title | Journal |
|---|---|
| Comparison of a homologous series of benzonaphthyridine anti-cancer agents in mice: divergence between tumour and plasma pharmacokinetics. | Cancer chemotherapy and pharmacology 20120701 |
| A rapid LC-MS/MS method for the quantitation of a series of benzonaphthyridine derivatives: application to in vivo pharmacokinetic and lipophilicity studies in drug development. | Journal of pharmaceutical and biomedical analysis 20120407 |
| In vivo and in vitro assessment of the action of SN 28049, a benzonaphthyridine derivative targeting topoisomerase II, on the murine Colon 38 carcinoma. | Investigational new drugs 20111201 |
| ATP and its N⁶-substituted analogues: parameterization, molecular dynamics simulation and conformational analysis. | Journal of molecular modeling 20110501 |
| Synthesis and anti-intestinal nematode activity of variously substituted benzonaphthyridine derivatives. | Molecules (Basel, Switzerland) 20110214 |
| Antiproliferative effect of aaptamine on human chronic myeloid leukemia K562 cells. | International journal of molecular sciences 20110101 |
| Absorption, distribution, excretion, and pharmacokinetics of 14C-pyronaridine tetraphosphate in male and female Sprague-Dawley rats. | Journal of biomedicine & biotechnology 20100101 |
| The reactivity patterns of low-coordinate iron-hydride complexes. | Journal of the American Chemical Society 20080521 |
| Effect of folate derivatives on the activity of antifolate drugs used against malaria and cancer. | Parasitology research 20080501 |
| Chain-length effects on molecular conformation in and chirality of self-assembled monolayers of alkoxylated benzo[c]cinnoline derivatives on highly oriented pyrolytic graphite. | The journal of physical chemistry. B 20060810 |
| Aaptamine, a spongean alkaloid, activates p21 promoter in a p53-independent manner. | Biochemical and biophysical research communications 20060331 |
| Neutral Cu4N12 and Ag4N12 metallacycles with a para-cyclophane framework assembled from copper(I) and silver(I) pyrazolates and pyridazine. | Chemical communications (Cambridge, England) 20050328 |
| Investigations of a novel process to the framework of benzo[c]cinnoline. | The Journal of organic chemistry 20041029 |
| Mechanisms of anion secretion in Calu-3 human airway epithelial cells by 7,8-benzoquinoline. | British journal of pharmacology 20030901 |
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