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Home > Other Building Blocks > 2292-79-7
2292-79-7 | 3,5,1,7-[1,2,3,4]Butanetetraylnaphthalene, decahydro-
CAS No: 2292-79-7 Catalog No: AG002LIU MDL No:MFCD00171301
Product Description
Catalog Number:
AG002LIU
Chemical Name:
3,5,1,7-[1,2,3,4]Butanetetraylnaphthalene, decahydro-
CAS Number:
2292-79-7
Molecular Formula:
C14H20
Molecular Weight:
188.3086
MDL Number:
MFCD00171301
IUPAC Name:
pentacyclo[7.3.1.14,12.02,7.06,11]tetradecane
InChI:
InChI=1S/C14H20/c1-7-2-12-10-4-8-5-11(9(1)10)13(3-7)14(12)6-8/h7-14H,1-6H2
InChI Key:
ZICQBHNGXDOVJF-UHFFFAOYSA-N
SMILES:
C1C2CC3C4C1C1C(C2)C3CC(C1)C4
UNII:
KYM5H16I3I
Properties
Complexity:
205
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
188.157g/mol
Formal Charge:
0
Heavy Atom Count:
14
Hydrogen Bond Acceptor Count:
0
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
188.314g/mol
Monoisotopic Mass:
188.157g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
0A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
4.4
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| Nonequilibrium Fermi golden rule for electronic transitions through conical intersections. | The Journal of chemical physics 20111221 |
| Kinetic and mechanistic insight into the thermodynamic degradation of saxagliptin. | The Journal of organic chemistry 20111216 |
| Huge dielectric response and molecular motions in paddle-wheel [Cu(II)2(adamantylcarboxylate)4(DMF)2]⋅(DMF)2. | Chemistry (Weinheim an der Bergstrasse, Germany) 20111216 |
| Adamantane-platinum conjugate hosted in β-cyclodextrin: enhancing transport and cytotoxicity by noncovalent modification. | Bioorganic & medicinal chemistry letters 20111215 |
| Investigating the antimalarial action of 1,2,4-trioxolanes with fluorescent chemical probes. | Journal of medicinal chemistry 20111208 |
| Combined anticancer effects of sphingosine kinase inhibitors and sorafenib. | Investigational new drugs 20111201 |
| Long-term treatment with the dipeptidyl peptidase-4 inhibitor saxagliptin in patients with type 2 diabetes mellitus and renal impairment: a randomised controlled 52-week efficacy and safety study. | International journal of clinical practice 20111201 |
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| Oxidative Prins-pinacol tandem process mediated by a hypervalent iodine reagent: scope, limitations, and applications. | The Journal of organic chemistry 20111118 |
| Simultaneous interactions of anions and cations with cyclohexane and adamantane: aliphatic cyclic hydrocarbons as charge insulators. | The journal of physical chemistry. A 20111117 |
| Design, synthesis, and SAR studies of novel polycyclic acids as potent and selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1). | Bioorganic & medicinal chemistry letters 20111115 |
| Multiplexing interactions to control antibiotic release from cyclodextrin hydrogels. | Macromolecular bioscience 20111110 |
| Synthesis, antimicrobial and antiproliferative activity of novel silver(I) tris(pyrazolyl)methanesulfonate and 1,3,5-triaza-7-phosphadamantane complexes. | Inorganic chemistry 20111107 |
| Selective inhibition of striatal fast-spiking interneurons causes dyskinesias. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20111102 |
| Adaphostin promotes caffeine-evoked autocrine Fas-mediated death pathway activation in Bcr/Abl-positive leukaemia cells. | The Biochemical journal 20111101 |
| Inhibition of epoxy-eicosanoid degradation improves the tocolytic effects of indomethacin in the uterus from pregnant women. | Prostaglandins & other lipid mediators 20111101 |
| Naja nigricollis CMS-9 enhances the mitochondria-mediated death pathway in adaphostin-treated human leukaemia U937 cells. | Clinical and experimental pharmacology & physiology 20111101 |
| Target-mediated metabolism and target-mediated drug disposition of the DPPIV inhibitor AMG 222. | Xenobiotica; the fate of foreign compounds in biological systems 20111101 |
| Efficacy and safety of saxagliptin added to metformin in Asian people with type 2 diabetes mellitus: a randomized controlled trial. | Diabetes research and clinical practice 20111101 |
| Platensimycin and platencin: promising antibiotics for future application in human medicine. | The Journal of antibiotics 20111101 |
| In vivo transfection using cyclodextrin-containing polycations. | Cold Spring Harbor protocols 20111101 |
| The design and rationale of the saxagliptin assessment of vascular outcomes recorded in patients with diabetes mellitus-thrombolysis in myocardial infarction (SAVOR-TIMI) 53 study. | American heart journal 20111101 |
| Emerging role of DPP-4 inhibitor Vildagliptin in the management of type-2 diabetes. | The Journal of the Association of Physicians of India 20111101 |
| Mono- and dinuclear iron complexes of bis(1-methylimidazol-2-yl)ketone (bik): structure, magnetic properties, and catalytic oxidation studies. | Inorganic chemistry 20111003 |
| Safety and efficacy of vildagliptin versus placebo in patients with type 2 diabetes and moderate or severe renal impairment: a prospective 24-week randomized placebo-controlled trial. | Diabetes, obesity & metabolism 20111001 |
| N-Arylalkyl-2-azaadamantanes as cage-expanded polycarbocyclic sigma (σ) receptor ligands. | Bioorganic & medicinal chemistry letters 20110915 |
| Identification of SQ609 as a lead compound from a library of dipiperidines. | Bioorganic & medicinal chemistry letters 20110915 |
| Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection. | Nature 20110915 |
| Synthesis and SAR requirements of adamantane-colchicine conjugates with both microtubule depolymerizing and tubulin clustering activities. | Bioorganic & medicinal chemistry 20110915 |
| [Dipeptidyl-peptidase-4 inhibitors (gliptins): a new class of oral antidiabetic drugs]. | Orvosi hetilap 20110911 |
| Size-controlled nanoassemblies based on cyclodextrin-modified dextrans. | Macromolecular bioscience 20110909 |
| Adamantyl ethanone pyridyl derivatives: potent and selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1. | ChemMedChem 20110905 |
| Mechanisms of action of the dipeptidyl peptidase-4 inhibitor vildagliptin in humans. | Diabetes, obesity & metabolism 20110901 |
| Effects of saxagliptin on β-cell stimulation and insulin secretion in patients with type 2 diabetes. | Diabetes, obesity & metabolism 20110901 |
| The metabolic syndrome influences the response to incretin-based therapies. | Acta diabetologica 20110901 |
| Experimental studies and modeling of drug release from a tunable affinity-based drug delivery platform. | Annals of biomedical engineering 20110901 |
| Efficacy of saxagliptin as an add-on to oral monotherapy in the phase 3 clinical development program: predictive factors of the treatment response in type 2 diabetes. | Annales d'endocrinologie 20110901 |
| Vildagliptin improves endothelium-dependent vasodilatation in type 2 diabetes. | Diabetes care 20110901 |
| Platensimycin and its relatives: a recent story in the struggle to develop new naturally derived antibiotics. | Natural product reports 20110901 |
| [Influenza : clinical symptoms, diagnostics and therapy]. | Der Internist 20110901 |
| HYDRAmers: design, synthesis and characterization of different generation novel Hydra-like dendrons based on multifunctionalized adamantane. | Chemical communications (Cambridge, England) 20110821 |
| Cyclodextrin and adamantane host-guest interactions of modified hyperbranched poly(ethylene imine) as mimetics for biological membranes. | Angewandte Chemie (International ed. in English) 20110816 |
| Investigations on the 4-quinolone-3-carboxylic acid motif. 4. Identification of new potent and selective ligands for the cannabinoid type 2 receptor with diverse substitution patterns and antihyperalgesic effects in mice. | Journal of medicinal chemistry 20110811 |
| Ordered phases of encapsulated diamondoids into carbon nanotubes. | Nanotechnology 20110805 |
| Ongoing clinical trials evaluating the cardiovascular safety and efficacy of therapeutic approaches to diabetes mellitus. | The American journal of cardiology 20110802 |
| Beta cell function following 1 year vildagliptin or placebo treatment and after 12 week washout in drug-naive patients with type 2 diabetes and mild hyperglycaemia: a randomised controlled trial. | Diabetologia 20110801 |
| Dipeptidyl peptidase-4 inhibition increases portal concentrations of intact glucagon-like peptide-1 (GLP-1) to a greater extent than peripheral concentrations in anaesthetised pigs. | Diabetologia 20110801 |
| Could LogP be a principal determinant of biological activity in 18-crown-6 ethers? Synthesis of biologically active adamantane-substituted diaza-crowns. | European journal of medicinal chemistry 20110801 |
| Vildagliptin in the treatment of type 2 diabetes mellitus. | Expert opinion on pharmacotherapy 20110801 |
| Saxagliptin: a clinical review in the treatment of type 2 diabetes mellitus. | Clinical therapeutics 20110801 |
| New synthesis of 6[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid and evaluation of the influence of adamantyl group on the DNA binding of a naphthoic retinoid. | Bioorganic chemistry 20110801 |
| Place in therapy for liraglutide and saxagliptin for type 2 diabetes and FDA liraglutide warning. | Southern medical journal 20110801 |
| The Suzuki reaction in aqueous media promoted by P, N ligands. | Molecules (Basel, Switzerland) 20110725 |
| Saxagliptin, a potent, selective inhibitor of DPP-4, does not alter the pharmacokinetics of three oral antidiabetic drugs (metformin, glyburide or pioglitazone) in healthy subjects. | Diabetes, obesity & metabolism 20110701 |
| Ligand-dependent regulation of the activity of the orphan nuclear receptor, small heterodimer partner (SHP), in the repression of bile acid biosynthetic CYP7A1 and CYP8B1 genes. | Molecular endocrinology (Baltimore, Md.) 20110701 |
| Comparison of the dipeptidyl peptidase-4 inhibitor vildagliptin and the sulphonylurea gliclazide in combination with metformin, in Muslim patients with type 2 diabetes mellitus fasting during Ramadan: results of the VECTOR study. | Current medical research and opinion 20110701 |
| Thorough QT study of the effects of vildagliptin, a dipeptidyl peptidase IV inhibitor, on cardiac repolarization and conduction in healthy volunteers. | Current medical research and opinion 20110701 |
| Effect of rifampicin on the pharmacokinetics and pharmacodynamics of saxagliptin, a dipeptidyl peptidase-4 inhibitor, in healthy subjects. | British journal of clinical pharmacology 20110701 |
| Synthesis and evaluation of fluorescent heterocyclic aminoadamantanes as multifunctional neuroprotective agents. | Bioorganic & medicinal chemistry 20110701 |
| Efficacy and safety of saxagliptin combination therapy in US patients with type 2 diabetes. | Postgraduate medicine 20110701 |
| What happens to hydrophobic interactions during transfer from the solution to the gas phase? The case of electrospray-based soft ionization methods. | Journal of the American Society for Mass Spectrometry 20110701 |
| How do aminoadamantanes block the influenza M2 channel, and how does resistance develop? | Journal of the American Chemical Society 20110629 |
| Probing multivalent host-guest interactions between modified polymer layers by direct force measurement. | The journal of physical chemistry. B 20110623 |
| Heteroatom-substituted analogues of orphan nuclear receptor small heterodimer partner ligand and apoptosis inducer (E)-4-[3-(1-Adamantyl)-4-hydroxyphenyl]-3-chlorocinnamic acid. | Journal of medicinal chemistry 20110609 |
| An adamantane-based building block for DNA networks. | Chemistry, an Asian journal 20110606 |
| Saxagliptin improves glycaemic control and is well tolerated in patients with type 2 diabetes mellitus and renal impairment. | Diabetes, obesity & metabolism 20110601 |
| Initial combination therapy with saxagliptin and metformin provides sustained glycaemic control and is well tolerated for up to 76 weeks. | Diabetes, obesity & metabolism 20110601 |
| The many faces of the adamantyl group in drug design. | European journal of medicinal chemistry 20110601 |
| Adamantanes as spherical nanosondes in adducts with a chiral dirhodium complex-discriminating enantiomers and probing spatial proximities. | Magnetic resonance in chemistry : MRC 20110601 |
| Effectiveness of adding vildagliptin to the treatment of diabetic patients nonresponsive to the combination of metformin and a sulphonylurea. | Arquivos brasileiros de endocrinologia e metabologia 20110601 |
| Place in therapy for liraglutide and saxagliptin for type 2 diabetes. | Southern medical journal 20110601 |
| Recent diabetes issues affecting the primary care clinician. | Southern medical journal 20110601 |
| A supramolecular approach to the preparation of charge-tunable dendritic polycations for efficient gene delivery. | Chemical communications (Cambridge, England) 20110521 |
| A versatile Fréchet-dendron compound unifies host-guest and templated heterogeneous self-assembly. | Advanced materials (Deerfield Beach, Fla.) 20110517 |
| Identification of individual tetra- and pentacyclic naphthenic acids in oil sands process water by comprehensive two-dimensional gas chromatography/mass spectrometry. | Rapid communications in mass spectrometry : RCM 20110515 |
| Highly substituted oxabicyclic derivatives from furan: synthesis of (±)-platensimycin. | Organic letters 20110506 |
| Enzymatic preparation of 5-hydroxy-L-proline, N-Cbz-5-hydroxy-L-proline, and N-Boc-5-hydroxy-L-proline from (α-N-protected)-L-ornithine using a transaminase or an amine oxidase. | Enzyme and microbial technology 20110506 |
| Highly efficient, organocatalytic aerobic alcohol oxidation. | Journal of the American Chemical Society 20110504 |
| An analysis of the impact of FDA's guidelines for addressing cardiovascular risk of drugs for type 2 diabetes on clinical development. | Contemporary clinical trials 20110501 |
| Vildagliptin blocks vascular injury in thoracic aorta of diabetic rats by suppressing advanced glycation end product-receptor axis. | Pharmacological research 20110501 |
| DPP-4 inhibitors: impact on glycemic control and cardiovascular risk factors. | Diabetes care 20110501 |
| [Vildagliptin]. | Nihon rinsho. Japanese journal of clinical medicine 20110501 |
| Highly regioselective amination of unactivated alkanes by hypervalent sulfonylimino-λ³-bromane. | Science (New York, N.Y.) 20110422 |
| Inhibitory effect of N-adamantyl-3,4-dihydroxybenzamide on melanogenesis in melan-a cells and brown guinea pigs. | Archives of dermatological research 20110401 |
| Attenuation of arthritis in rodents by a novel orally-available inhibitor of sphingosine kinase. | Inflammopharmacology 20110401 |
| Neuropeptide FF receptor antagonist, RF9, attenuates the fever induced by central injection of LPS in mice. | Peptides 20110401 |
| Inhibition of DPP-4 with vildagliptin improved insulin secretion in response to oral as well as 'isoglycemic' intravenous glucose without numerically changing the incretin effect in patients with type 2 diabetes. | The Journal of clinical endocrinology and metabolism 20110401 |
| Soluble epoxide hydrolase in the generation and maintenance of high blood pressure in spontaneously hypertensive rats. | American journal of physiology. Endocrinology and metabolism 20110401 |
| Adamantanyl-histone deacetylase inhibitor H6CAHA exhibits favorable pharmacokinetics and augments prostate cancer radiation sensitivity. | International journal of radiation oncology, biology, physics 20110401 |
| Targeting NFĸB mediated breast cancer chemoresistance through selective inhibition of sphingosine kinase-2. | Cancer biology & therapy 20110401 |
| Activity of OZ78 analogues against Fasciola hepatica and Echinostoma caproni. | Acta tropica 20110401 |
| Efficacy and safety of saxagliptin in older patients with type 2 diabetes mellitus. | Current medical research and opinion 20110401 |
| Influence of renal or hepatic impairment on the pharmacokinetics of saxagliptin. | Clinical pharmacokinetics 20110401 |
| FDA's first active medical product surveillance eyes antidiabetic-MI link. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110401 |
| Multivalent interactions: a hop, skip and jump. | Nature chemistry 20110401 |
| Gradient-driven motion of multivalent ligand molecules along a surface functionalized with multiple receptors. | Nature chemistry 20110401 |
| Dihydrogen contacts in alkanes are subtle but not faint. | Nature chemistry 20110401 |
| Understanding the incretin effect. | The Journal of clinical endocrinology and metabolism 20110401 |
| Safety and efficacy of saxagliptin added to thiazolidinedione over 76 weeks in patients with type 2 diabetes mellitus. | Diabetes & vascular disease research 20110401 |
| Safety and efficacy of saxagliptin in combination with submaximal sulphonylurea versus up-titrated sulphonylurea over 76 weeks. | Diabetes & vascular disease research 20110401 |
| Emerging role of dipeptidyl peptidase-IV (DPP-4) inhibitor vildagliptin in the management of type 2 diabetes. | The Journal of the Association of Physicians of India 20110401 |
| Specific binding of adamantane drugs and direction of their polar amines in the pore of the influenza M2 transmembrane domain in lipid bilayers and dodecylphosphocholine micelles determined by NMR spectroscopy. | Journal of the American Chemical Society 20110330 |
| Platensimycin and platencin congeners from Streptomyces platensis. | Journal of natural products 20110325 |
| Dipeptidyl peptidase IV dependent water-soluble prodrugs of highly lipophilic bicyclic nucleoside analogues. | Journal of medicinal chemistry 20110324 |
| Structure-activity relationships of cycloalkylamide derivatives as inhibitors of the soluble epoxide hydrolase. | Journal of medicinal chemistry 20110324 |
| Saxagliptin/metformin (kombiglyze XR) for type 2 diabetes. | The Medical letter on drugs and therapeutics 20110321 |
| New ultrahigh affinity host-guest complexes of cucurbit[7]uril with bicyclo[2.2.2]octane and adamantane guests: thermodynamic analysis and evaluation of M2 affinity calculations. | Journal of the American Chemical Society 20110316 |
| Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malaria. | Proceedings of the National Academy of Sciences of the United States of America 20110315 |
| Dialkylamino-2,4-dihydroxybenzoic acids as easily synthesized analogues of platensimycin and platencin with comparable antibacterial properties. | Chemistry (Weinheim an der Bergstrasse, Germany) 20110314 |
| Semi-metallic single-component crystal of soluble La@C82 derivative with high electron mobility. | Journal of the American Chemical Society 20110302 |
| Synthesis, structures and in vitro cytotoxicity of some cationic cis-platinum(II) complexes containing chelating thiocarbamates. | Journal of inorganic biochemistry 20110301 |
| Current approaches to exploit actinomycetes as a source of novel natural products. | Journal of industrial microbiology & biotechnology 20110301 |
| Inhibition of soluble epoxide hydrolase attenuates endothelial dysfunction in animal models of diabetes, obesity and hypertension. | European journal of pharmacology 20110301 |
| Clinical evidence and mechanistic basis for vildagliptin's action when added to metformin. | Diabetes, obesity & metabolism 20110301 |
| Synthesis and antiviral evaluation of bisnoradamantane sulfites and related compounds. | Medicinal chemistry (Shariqah (United Arab Emirates)) 20110301 |
| Antitumor activity of sphingosine kinase 2 inhibitor ABC294640 and sorafenib in hepatocellular carcinoma xenografts. | Cancer biology & therapy 20110301 |
| Time course of histone deacetylase 1 and acetylated H3 and H4 histones in the brain of rats treated with ladasten. | Bulletin of experimental biology and medicine 20110301 |
| Synthesis of 1,8-di(1-adamantyl)naphthalenes as single enantiomers stable at ambient temperatures. | Chemical communications (Cambridge, England) 20110207 |
| Water-soluble Cp ruthenium complex containing 1,3,5-triaza-7-phosphaadamantane and 8-thiotheophylline derivatives: synthesis, characterization, and antiproliferative activity. | Inorganic chemistry 20110207 |
| Resistance characteristics of influenza to amino-adamantyls. | Biochimica et biophysica acta 20110201 |
| Inhibition of recombinant N-type and native high voltage-gated neuronal Ca2+ channels by AdGABA: mechanism of action studies. | Toxicology and applied pharmacology 20110201 |
| 1-(1-acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia. | Bioorganic & medicinal chemistry letters 20110201 |
| Oseltamivir-resistant pandemic (H1N1) 2009 virus, Mexico. | Emerging infectious diseases 20110201 |
| [Adamantane resistance among seasonal influenza A viruses between January to October in Guangzhou, 2009]. | Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20110201 |
| Conformationally restricted GABA analogs: from rigid carbocycles to cage hydrocarbons. | Future medicinal chemistry 20110201 |
| Incretin therapies in the management of elderly patients with type 2 diabetes mellitus. | Hospital practice (1995) 20110201 |
| Saxagliptin. No more effective than other gliptins, but a high potential for drug interactions. | Prescrire international 20110201 |
| The DPP-4 inhibitor vildagliptin increases pancreatic beta cell mass in neonatal rats. | European journal of pharmacology 20110115 |
| The dipeptidyl peptidase IV (CD26, EC 3.4.14.5) inhibitor vildagliptin is a potent antihyperalgesic in rats by promoting endomorphin-2 generation in the spinal cord. | European journal of pharmacology 20110110 |
| Antiviral drugs for influenza. | The Medical letter on drugs and therapeutics 20110110 |
| Tuning the conversion of cyclohexane into cyclohexanol/one by molecular dioxygen, protons and reducing agents at a single non-porphyrinic iron centre and chemical versatility of the tris(2-pyridylmethyl)amine TPAFe(II)Cl2 complex in mild oxidation chemistry. | Dalton transactions (Cambridge, England : 2003) 20110107 |
| Supramolecular thermoresponsive hyperbranched polymers constructed from poly(N-isopropylacrylamide) containing one adamantyl and two β-cyclodextrin terminal moieties. | Macromolecular rapid communications 20110103 |
| Maximal adamantyl-substituted retinoid-related molecule-induced apoptosis requires NF-κB noncanonical and canonical pathway activation. | Cell death and differentiation 20110101 |
| Structure-based and property-compliant library design of 11β-HSD1 adamantyl amide inhibitors. | Methods in molecular biology (Clifton, N.J.) 20110101 |
| Discovery of a novel IKK-β inhibitor by ligand-based virtual screening techniques. | Bioorganic & medicinal chemistry letters 20110101 |
| Synthesis and 11β hydroxysteroid dehydrogenase 1 inhibition of thiazolidine derivatives with an adamantyl group. | Bioorganic & medicinal chemistry letters 20110101 |
| Clinical experience with vildagliptin in the management of type 2 diabetes in a patient population ≥75 years: a pooled analysis from a database of clinical trials. | Diabetes, obesity & metabolism 20110101 |
| Molecular and structural determinants of adamantyl susceptibility to HLA-DRs allelic variants: an in silico approach to understand the mechanism of MLEs. | Journal of computer-aided molecular design 20110101 |
| On the mechanisms of bananin activity against severe acute respiratory syndrome coronavirus. | The FEBS journal 20110101 |
| Emerging influenza antiviral resistance threats. | The Journal of infectious diseases 20110101 |
| Dual resistance to adamantanes and oseltamivir among seasonal influenza A(H1N1) viruses: 2008-2010. | The Journal of infectious diseases 20110101 |
| Focus on incretin-based therapies: targeting the core defects of type 2 diabetes. | Postgraduate medicine 20110101 |
| Anti-amnesic and neuroprotective actions of the sigma-1 receptor agonist (-)-MR22 in rats with selective cholinergic lesion and amyloid infusion. | Journal of Alzheimer's disease : JAD 20110101 |
| Vildagliptin-induced acute pancreatitis. | Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20110101 |
| Comments on the article 'Effects of vildagliptin twice daily vs. sitagliptin once daily on 24-hour acute glucose fluctuations' by Marfella et al.: (Journal of Diabetes and Its Complications 24 [2010] 79-83). | Journal of diabetes and its complications 20110101 |
| Experimental osteoarthritis in rats is attenuated by ABC294640, a selective inhibitor of sphingosine kinase-2. | Pharmacology 20110101 |
| Assessing the general safety and tolerability of vildagliptin: value of pooled analyses from a large safety database versus evaluation of individual studies. | Vascular health and risk management 20110101 |
| [Ladasten in the management of non-motor symptoms of Parkinson's disease]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101 |
| [Plasmapheresis as treatment for severe hypertriglyceridemia]. | Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20110101 |
| [A comparative study of hemantane and amantadine effects on dopamine transporter expression in brain of normal and MPTP-treated C57BL/6 mice]. | Eksperimental'naia i klinicheskaia farmakologiia 20110101 |
| [New adamantane derivatives and ways of overcoming the resistance of influenza A viruses to rimantadine and amantadine]. | Voprosy virusologii 20110101 |
| Fibrous architectures and organogels of tris(phenylethynylphenyl)adamantane molecules with amino acid moieties: their solvato-controlled helicity induction. | Chirality 20110101 |
| Effect of enhanced glycemic control with saxagliptin on endothelial nitric oxide release and CD40 levels in obese rats. | Journal of atherosclerosis and thrombosis 20110101 |
| Incretin-based therapy and pancreatitis-what is the risk? | Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20110101 |
| Reply to the 'Comments on the article 'Effects of vildagliptin twice daily vs. sitagliptin once daily on 24-hour acute glucose fluctuations'', by Avogaro (Journal of Diabetes and Its Complications 25 [2011] 352-353). | Journal of diabetes and its complications 20110101 |
| [Influence of hemantane and doxycycline on MPTP-evoked behavior violations in C57BL/6 mice]. | Eksperimental'naia i klinicheskaia farmakologiia 20110101 |
| Bioequivalence of saxagliptin/metformin extended-release (XR) fixed-dose combination tablets and single-component saxagliptin and metformin XR tablets in healthy adult subjects. | Clinical drug investigation 20110101 |
| Comparative efficacy of vildagliptin and sitagliptin in Japanese patients with type 2 diabetes mellitus: a matching-adjusted indirect comparison of randomized trials. | Clinical drug investigation 20110101 |
| [Comparative study of amantadine and hemantane effects on development of levodopa-induced dyskinesia in rat model of parkinsonian syndrome]. | Eksperimental'naia i klinicheskaia farmakologiia 20110101 |
| Glycosphingolipids and insulin resistance. | Advances in experimental medicine and biology 20110101 |
| The dipeptidyl peptidase-4 (DPP-4) inhibitor vildagliptin improves glycemic control in type 2 diabetic patients undergoing hemodialysis. | Endocrine journal 20110101 |
| Early and late effects of the DPP-4 inhibitor vildagliptin in a rat model of post-myocardial infarction heart failure. | Cardiovascular diabetology 20110101 |
| 9-Azanoradamantane N-oxyl (Nor-AZADO): a highly active organocatalyst for alcohol oxidation. | Chemical & pharmaceutical bulletin 20110101 |
| [Investigation of antiviral activity of adamantan boron derivaties on pandemic influenza virus models]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20110101 |
| [Analysis of the binding capacity of the benzodiazepine site of gabaa receptor in mice C57BL/6 and BALB/C pretreated with anxiolytics]. | Eksperimental'naia i klinicheskaia farmakologiia 20110101 |
| [Effect of antiasthenic drug ladasten on the level of cytokines and behavior in experimental model of anxious depression in C57BL/6 male mice]. | Eksperimental'naia i klinicheskaia farmakologiia 20110101 |
| [Self-evaluation of single test doses and objective indices of ladasten vs. placebo efficacy in neurasthenic patients]. | Eksperimental'naia i klinicheskaia farmakologiia 20110101 |
| [Pharmacokinetics of hemantane in rats]. | Eksperimental'naia i klinicheskaia farmakologiia 20110101 |
| [Present and future in the use of anti-tubercular drugs]. | Pneumologia (Bucharest, Romania) 20110101 |
| [Characterization of patients with type 2 diabetes treated with vildagliptin]. | Acta medica portuguesa 20110101 |
| Concise formal total synthesis of platensimycin mediated by a stereoselective autoxidation and hydroxyl group directed conjugative reduction. | Organic letters 20101217 |
| Pressure perturbation calorimetry and the thermodynamics of noncovalent interactions in water: comparison of protein-protein, protein-ligand, and cyclodextrin-adamantane complexes. | The journal of physical chemistry. B 20101216 |
| Synthesis and structure-activity relationship of tetrahydropyrazolopyrimidine derivatives--a novel structural class of potent calcium-sensing receptor antagonists. | Bioorganic & medicinal chemistry 20101215 |
| A bismuth(III)-catalyzed Friedel-Crafts cyclization and stereocontrolled organocatalytic approach to (-)-platensimycin. | Organic letters 20101203 |
| Drugs in development for tuberculosis. | Drugs 20101203 |
| Comparative embryotoxicity of different antimalarial peroxides: in vitro study using the rat whole embryo culture model (WEC). | Reproductive toxicology (Elmsford, N.Y.) 20101201 |
| Influence of an additional amino group on the potency of aminoadamantanes against influenza virus A. II - Synthesis of spiropiperazines and in vitro activity against influenza A H3N2 virus. | Bioorganic chemistry 20101201 |
| Tuning hydrophobicity of highly cationic tetradecameric Gramicidin S analogues using adamantane amino acids. | Bioorganic & medicinal chemistry 20101201 |
| Electrophysiological analysis of the inhibitory effects of FMRFamide-like peptides on the pacemaker activity of gonadotropin-releasing hormone neurons. | Journal of neurophysiology 20101201 |
| β-cyclodextrin as the vehicle for forming ratiometric mercury ion sensor usable in aqueous media, biological fluids, and live cells. | Langmuir : the ACS journal of surfaces and colloids 20101116 |
| Discovery and optimization of adamantyl carbamate inhibitors of 11β-HSD1. | Bioorganic & medicinal chemistry letters 20101115 |
| Vildagliptin: a review of its use in type 2 diabetes mellitus. | Drugs 20101112 |
| Pyridoindole derivative as electron transporting host material for efficient deep-blue phosphorescent organic light-emitting diodes. | Advanced materials (Deerfield Beach, Fla.) 20101109 |
| Safety and tolerability of vildagliptin vs. thiazolidinedione as add-on to metformin in type 2 diabetic patients with and without mild renal impairment: a retrospective analysis of the GALIANT study. | Diabetes research and clinical practice 20101101 |
| DPP-4 inhibitors: what may be the clinical differentiators? | Diabetes research and clinical practice 20101101 |
| Multidrug therapy in a patient with Rabson-Mendenhall syndrome. | Diabetologia 20101101 |
| Influenza antiviral prescribing practices during the 2007-08 and 2008-09 influenza seasons in the setting of increased resistance to oseltamivir among circulating influenza viruses. | Antiviral research 20101101 |
| Design and synthesis of bioactive adamantanaminoalcohols and adamantanamines. | European journal of medicinal chemistry 20101101 |
| Saxagliptin is non-inferior to glipizide in patients with type 2 diabetes mellitus inadequately controlled on metformin alone: a 52-week randomised controlled trial. | International journal of clinical practice 20101101 |
| Observation of NMR noise from solid samples. | Journal of magnetic resonance (San Diego, Calif. : 1997) 20101101 |
| Antiestrogenic effects of the novel sphingosine kinase-2 inhibitor ABC294640. | Endocrinology 20101101 |
| Influenza 2010-2011: lessons from the 2009 pandemic. | Cleveland Clinic journal of medicine 20101101 |
| Adamantyl-substituted retinoid-related molecules induce apoptosis in human acute myelogenous leukemia cells. | Molecular cancer therapeutics 20101101 |
| [Preclinical and clinical findings of the dipeptidyl peptidase-4 inhibitor vildagliptin]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20101101 |
| Proteomic analysis and identification of ladasten target proteins in rat brain. | Bulletin of experimental biology and medicine 20101101 |
| [Effects of subchronic hemantane administration on dopamine and serotonin receptors in intact and MPP+-treated rat brain ex vivo]. | Eksperimental'naia i klinicheskaia farmakologiia 20101101 |
| Efficacy, safety and pharmacokinetics of 1,2,4-trioxolane OZ78 against an experimental infection with Fasciola hepatica in sheep. | Veterinary parasitology 20101029 |
| An adamantyl amino acid containing gramicidin S analogue with broad spectrum antibacterial activity and reduced hemolytic activity. | Chemistry (Weinheim an der Bergstrasse, Germany) 20101025 |
| Development and validation of a liquid chromatography/mass spectrometry method for pharmacokinetic studies of OZ78, a fasciocidal drug candidate. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101015 |
| Facile fabrication of narrowly-distributed polymeric micelles via host-guest inclusion complexation of hyperbranched polymers and cyclodextrin and its two-dimensional self-assembly. | Physical chemistry chemical physics : PCCP 20101014 |
| 1-Aryl-3-(1-acylpiperidin-4-yl)urea inhibitors of human and murine soluble epoxide hydrolase: structure-activity relationships, pharmacokinetics, and reduction of inflammatory pain. | Journal of medicinal chemistry 20101014 |
| Catalytic enantioselective alkylative dearomatization-annulation: total synthesis and absolute configuration assignment of hyperibone K. | Journal of the American Chemical Society 20101006 |
| An oxidative Prins-pinacol tandem process and its application to the synthesis of (-)-platensimycin. | Chemistry (Weinheim an der Bergstrasse, Germany) 20101004 |
| Effect of a high-fat meal on the pharmacokinetics of saxagliptin in healthy subjects. | Journal of clinical pharmacology 20101001 |
| Opposite control of body temperature by NPFF1 and NPFF2 receptors in mice. | Neuropeptides 20101001 |
| LW6, a novel HIF-1 inhibitor, promotes proteasomal degradation of HIF-1alpha via upregulation of VHL in a colon cancer cell line. | Biochemical pharmacology 20101001 |
| Suppression of colitis-driven colon cancer in mice by a novel small molecule inhibitor of sphingosine kinase. | Carcinogenesis 20101001 |
| Pharmacokinetics of lipoyl vildagliptin, a novel dipeptidyl peptidase IV inhibitor after oral administration in rats. | Xenobiotica; the fate of foreign compounds in biological systems 20101001 |
| Antivirals for influenza: strategies for use in pediatrics. | Paediatric drugs 20101001 |
| Saxagliptin and metformin XR combination therapy provides glycemic control over 24 hours in patients with T2DM inadequately controlled with metformin. | Current medical research and opinion 20101001 |
| Efficacy and safety of saxagliptin in combination with metformin compared with sitagliptin in combination with metformin in adult patients with type 2 diabetes mellitus. | Diabetes/metabolism research and reviews 20101001 |
| Synthesis of dibenzo[b,f][1,4]oxazepin-11(10H)-ones via intramolecular cyclocarbonylation reactions using PdI(2)/Cytop 292 as the catalytic system. | The Journal of organic chemistry 20100917 |
| Saxagliptin: a dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes mellitus. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100915 |
| Design and construction of an organic crystal with a novel interpenetrated n-Borromean linked topology. | Chemical communications (Cambridge, England) 20100914 |
| Effect of artemether, artesunate, OZ78, praziquantel, and tribendimidine alone or in combination chemotherapy on the tegument of Clonorchis sinensis. | Parasitology international 20100901 |
| Efficacy and tolerability of vildagliptin as an add-on to glimepiride in Japanese patients with Type 2 diabetes mellitus. | Diabetes research and clinical practice 20100901 |
| Combination therapy with nateglinide and vildagliptin improves postprandial metabolic derangements in Zucker fatty rats. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20100901 |
| Vildagliptin add-on to metformin produces similar efficacy and reduced hypoglycaemic risk compared with glimepiride, with no weight gain: results from a 2-year study. | Diabetes, obesity & metabolism 20100901 |
| Dipeptidylpeptidase-4 inhibitors (gliptins): focus on drug-drug interactions. | Clinical pharmacokinetics 20100901 |
| Distinguishing among incretin-based therapies. Glucose-lowering effects of incretin-based therapies. | The Journal of family practice 20100901 |
| Distinguishing among incretin-based therapies. Safety, tolerability, and nonglycemic effects of incretin-based therapies. | The Journal of family practice 20100901 |
| Distinguishing among incretin-based therapies. Patient education and self-management. | The Journal of family practice 20100901 |
| Distinguishing among incretin-based therapies. Introduction. | The Journal of family practice 20100901 |
| Distinguishing among incretin-based therapies. Pathophysiology of type 2 diabetes mellitus: potential role of incretin-based therapies. | The Journal of family practice 20100901 |
| Pharmacokinetics and pharmacodynamics of vildagliptin in Japanese patients with type 2 diabetes. | International journal of clinical pharmacology and therapeutics 20100901 |
| [Saxagliptin (Onglyza): new inhibitor of the dipeptidylpeptidase-4 for the oral treatment of type 2 diabetes]. | Revue medicale de Liege 20100901 |
| Proof of RNA interference in humans after systemic delivery of siRNAs. | Angewandte Chemie (International ed. in English) 20100823 |
| Heteroadamantyl cannabinoids. | Journal of medicinal chemistry 20100812 |
| Duplex of capped-cyclodextrins, synthesis and cross-linking behaviour with a biopolymer. | Organic & biomolecular chemistry 20100807 |
| Neurotrophic peptides incorporating adamantane improve learning and memory, promote neurogenesis and synaptic plasticity in mice. | FEBS letters 20100804 |
| A supramolecular bifunctional artificial enzyme with superoxide dismutase and glutathione peroxidase activities. | Bioorganic chemistry 20100801 |
| Effects of one year treatment of vildagliptin added to pioglitazone or glimepiride in poorly controlled type 2 diabetic patients. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20100801 |
| Managing type 2 diabetes in the primary care setting: beyond glucocentricity. | The American journal of the medical sciences 20100801 |
| Pharmacokinetics of dipeptidylpeptidase-4 inhibitors. | Diabetes, obesity & metabolism 20100801 |
| Efficacy and safety of vildagliptin and voglibose in Japanese patients with type 2 diabetes: a 12-week, randomized, double-blind, active-controlled study. | Diabetes, obesity & metabolism 20100801 |
| Saxagliptin efficacy. | Diabetes, obesity & metabolism 20100801 |
| Incretin-based therapies in the management of type 2 diabetes: rationale and reality in a managed care setting. | The American journal of managed care 20100801 |
| Nanosieving of anions and cavity-size-dependent association of cyclodextrins on a 1-adamantanethiol self-assembled monolayer. | ACS nano 20100727 |
| Syntheses, crystal structures and magnetic properties of a novel family of penta-manganese complexes derived from an assembly system containing polydentate hydroxy-rich Schiff-base ligands. | Dalton transactions (Cambridge, England : 2003) 20100721 |
| Adsorption of Cu2+ on spherical Fe-MCM-41 and its application for oxidation of adamantane. | Journal of hazardous materials 20100715 |
| Interaction of aminoadamantane derivatives with the influenza A virus M2 channel-docking using a pore blocking model. | Bioorganic & medicinal chemistry letters 20100715 |
| Spectroscopic study of the authentic emitter of AMPPD chemiluminescence in alkaline aqueous solution. | Physical chemistry chemical physics : PCCP 20100707 |
| Discovery of adamantyl ethanone derivatives as potent 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) inhibitors. | ChemMedChem 20100705 |
| Syntheses and crystal structures of a series of coordination polymers constructed from C2-symmetric ligand 1,3-adamantanedicarboxylic acid. | Chemistry, an Asian journal 20100705 |
| In vitro interactions between new antitubercular drug candidates SQ109 and TMC207. | Antimicrobial agents and chemotherapy 20100701 |
| Saxagliptin: a new drug for the treatment of type 2 diabetes. | Mini reviews in medicinal chemistry 20100701 |
| Modulation by salt intake of the vascular response mediated through adenosine A(2A) receptor: role of CYP epoxygenase and soluble epoxide hydrolase. | American journal of physiology. Regulatory, integrative and comparative physiology 20100701 |
| Role of vildagliptin in managing type 2 diabetes mellitus in the elderly. | Current medical research and opinion 20100701 |
| Glucagon-like peptide 1 prevents reactive oxygen species-induced endothelial cell senescence through the activation of protein kinase A. | Arteriosclerosis, thrombosis, and vascular biology 20100701 |
| Calcium-permeable AMPA receptors are involved in the induction and expression of l-DOPA-induced dyskinesia in Parkinson's disease. | Journal of neurochemistry 20100701 |
| Current development and future prospects in chemotherapy of tuberculosis. | Respirology (Carlton, Vic.) 20100701 |
| Hormonal and metabolic effects of morning or evening dosing of the dipeptidyl peptidase IV inhibitor vildagliptin in patients with type 2 diabetes. | British journal of clinical pharmacology 20100701 |
| Incretin physiology and its role in type 2 diabetes mellitus. | The Journal of the American Osteopathic Association 20100701 |
| Newer agents for blood glucose control in type 2 diabetes: systematic review and economic evaluation. | Health technology assessment (Winchester, England) 20100701 |
| Saxagliptin: a new dipeptidyl peptidase 4 inhibitor for type 2 diabetes. | The Annals of pharmacotherapy 20100601 |
| Bioconversion of 1-adamantanol to 1,3-adamantanediol using Streptomyces sp. SA8 oxidation system. | Journal of bioscience and bioengineering 20100601 |
| Assembly of a metal-organic framework by sextuple intercatenation of discrete adamantane-like cages. | Nature chemistry 20100601 |
| Assessing the cardio-cerebrovascular safety of vildagliptin: meta-analysis of adjudicated events from a large Phase III type 2 diabetes population. | Diabetes, obesity & metabolism 20100601 |
| An assessment of adverse effects of vildagliptin versus comparators on the liver, the pancreas, the immune system, the skin and in patients with impaired renal function from a large pooled database of Phase II and III clinical trials. | Diabetes, obesity & metabolism 20100601 |
| Structure-activity relationship of an ozonide carboxylic acid (OZ78) against Fasciola hepatica. | Journal of medicinal chemistry 20100527 |
| A 'clickable' hybrid nanocluster of cubic symmetry. | Chemistry (Weinheim an der Bergstrasse, Germany) 20100517 |
| Synthesis and evaluation of SQ109 analogues as potential anti-tuberculosis candidates. | European journal of medicinal chemistry 20100501 |
| Inhibition of glycosphingolipid synthesis induces a profound reduction of plasma cholesterol and inhibits atherosclerosis development in APOE*3 Leiden and low-density lipoprotein receptor-/- mice. | Arteriosclerosis, thrombosis, and vascular biology 20100501 |
| A novel sphingosine kinase inhibitor induces autophagy in tumor cells. | The Journal of pharmacology and experimental therapeutics 20100501 |
| Soluble epoxide hydrolase deficiency attenuates neointima formation in the femoral cuff model of hyperlipidemic mice. | Arteriosclerosis, thrombosis, and vascular biology 20100501 |
| Double (V27A/S31N) mutant 2009 pandemic influenza A (H1N1) virus isolated from adamantane non-treated inmunocompetent child. | Diagnostic microbiology and infectious disease 20100501 |
| The development and SAR of pyrrolidine carboxamide 11beta-HSD1 inhibitors. | Bioorganic & medicinal chemistry letters 20100501 |
| Graphic rule for drug metabolism systems. | Current drug metabolism 20100501 |
| A systematic assessment of cardiovascular outcomes in the saxagliptin drug development program for type 2 diabetes. | Postgraduate medicine 20100501 |
| Choosing among the incretin agents and why it matters. | The Journal of family practice 20100501 |
| [New hypoglycemic agents in type 2 diabetes]. | La Revue du praticien 20100420 |
| Searching for intermediates in Prins cyclisations: the 2-oxa-5-adamantyl carbocation. | Organic & biomolecular chemistry 20100407 |
| Computational structure-activity study directs synthesis of novel antitumor enkephalin analogs. | Amino acids 20100401 |
| Emergence of H5N1 avian influenza viruses with reduced sensitivity to neuraminidase inhibitors and novel reassortants in Lao People's Democratic Republic. | The Journal of general virology 20100401 |
| Changes in prandial glucagon levels after a 2-year treatment with vildagliptin or glimepiride in patients with type 2 diabetes inadequately controlled with metformin monotherapy. | Diabetes care 20100401 |
| Efficacy of a novel sphingosine kinase inhibitor in experimental Crohn's disease. | Inflammopharmacology 20100401 |
| Characterization of the potent gonadotropin-releasing activity of RF9, a selective antagonist of RF-amide-related peptides and neuropeptide FF receptors: physiological and pharmacological implications. | Endocrinology 20100401 |
| 7-Phenylplatensimycin and 11-methyl-7-phenylplatensimycin: more potent analogs of platensimycin. | Bioorganic & medicinal chemistry letters 20100401 |
| Discovery and syntheses of 'superbug challengers'-platensimycin and platencin. | Chemistry, an Asian journal 20100401 |
| Isolation, structure and biological activities of platencin A(2)-A(4) from Streptomyces platensis. | Bioorganic & medicinal chemistry 20100401 |
| Electronic and geometric effects of phosphatriazaadamantane ligands on the catalytic activity of an [FeFe] hydrogenase inspired complex. | Dalton transactions (Cambridge, England : 2003) 20100328 |
| A neurotensin agonist and antagonist decrease and increase activity, respectively, but do not preclude discrete cue conditioning. | Journal of psychopharmacology (Oxford, England) 20100301 |
| ASP4000, a slow-binding dipeptidyl peptidase 4 inhibitor, has antihyperglycemic activity of long duration in Zucker fatty rats. | Acta diabetologica 20100301 |
| Sensitization of ovarian carcinoma cells to the atypical retinoid ST1926 by the histone deacetylase inhibitor, RC307: enhanced DNA damage response. | International journal of cancer 20100301 |
| Safety of oseltamivir compared with the adamantanes in children less than 12 months of age. | The Pediatric infectious disease journal 20100301 |
| Improvement of secondary metabolite production in Streptomyces by manipulating pathway regulation. | Applied microbiology and biotechnology 20100301 |
| Sugar-decorated sugar vesicles: lectin-carbohydrate recognition at the surface of cyclodextrin vesicles. | Chemistry (Weinheim an der Bergstrasse, Germany) 20100301 |
| Synthesis and antiproliferative evaluation of certain indolo[3,2-c]quinoline derivatives. | Bioorganic & medicinal chemistry 20100301 |
| [DPP-4 inhibitors in clinical use. Therapy without the risk of hypoglycaemia]. | Pharmazie in unserer Zeit 20100301 |
| Qualitative GC-MS assessment of TCP and TAMORF elimination in rats. | Arhiv za higijenu rada i toksikologiju 20100301 |
| The physiologic role of incretin hormones: clinical applications. | The Journal of the American Osteopathic Association 20100301 |
| [Neurochemical study of effects of the new anxiolytic drugs afobazol and ladasten on the synthesis and metabolism of monoamines and their metabolites in the brain structures of Wistar rat on the model of monoamine synthesis blockade induced by aromatic amino acid decarboxylase inhibitor NSD-1015]. | Eksperimental'naia i klinicheskaia farmakologiia 20100301 |
| A comparison of efficacy and safety of vildagliptin and gliclazide in combination with metformin in patients with Type 2 diabetes inadequately controlled with metformin alone: a 52-week, randomized study. | Diabetic medicine : a journal of the British Diabetic Association 20100301 |
| Adamantyl-functionalized polymer monolith for capillary electrochromatography. | Journal of chromatography. A 20100226 |
| Liraglutide, but not vildagliptin, restores normoglycaemia and insulin content in the animal model of type 2 diabetes, Psammomys obesus. | Regulatory peptides 20100225 |
| Single-electron self-exchange between cage hydrocarbons and their radical cations in the gas phase. | Chemphyschem : a European journal of chemical physics and physical chemistry 20100222 |
| Study of branched cationic beta-cyclodextrin polymer/indomethacin complex and its release profile from alginate hydrogel. | International journal of pharmaceutics 20100215 |
| Quinolinotriazole-beta-cyclodextrin and its adamantanecarboxylic acid complex as efficient water-soluble fluorescent Cd(2+) sensors. | Bioorganic & medicinal chemistry 20100215 |
| Conjugates of desferrioxamine B (DFOB) with derivatives of adamantane or with orally available chelators as potential agents for treating iron overload. | Journal of medicinal chemistry 20100211 |
| Ca2+-permeable AMPA receptors mediate induction of test pulse depression of naive synapses in rat visual cortical slices at early postnatal stage. | Neuroscience 20100203 |
| Pharmacological characterization of the mouse NPFF2 receptor. | Peptides 20100201 |
| Medicinal Chemistry of Incretin Mimetics and DPP-4 Inhibitors. | ChemMedChem 20100201 |
| Efficacy of a new peracetic acid-based disinfectant agent ('Adaspor ready to use'). | The Journal of hospital infection 20100201 |
| Enhancing tumor vaccines: catalyzing MHC class II peptide exchange. | Expert review of vaccines 20100201 |
| [Role of the brain dopaminergic and serotoninergic systems in psychopharmacological effects of ladasten and sydnocarb]. | Eksperimental'naia i klinicheskaia farmakologiia 20100201 |
| Saxagliptin in type 2 diabetes. | Drugs of today (Barcelona, Spain : 1998) 20100201 |
| Application of the dipeptidyl peptidase IV (DPPIV/CD26) based prodrug approach to different amine-containing drugs. | Journal of medicinal chemistry 20100128 |
| Novel KCNQ2/Q3 agonists as potential therapeutics for epilepsy and neuropathic pain. | Journal of medicinal chemistry 20100128 |
| Potential of mean force of association of large hydrophobic particles: toward the nanoscale limit. | The journal of physical chemistry. B 20100121 |
| Synthesis and anti-viral activity of azolo-adamantanes against influenza A virus. | Bioorganic & medicinal chemistry 20100115 |
| Structure-reactivity relationships: reactions of a 5-substituted aziadamantane in a resorcin[4]arene-based cavitand. | Organic letters 20100115 |
| Effects of vildagliptin twice daily vs. sitagliptin once daily on 24-hour acute glucose fluctuations. | Journal of diabetes and its complications 20100101 |
| Sensorimotor gating in neurotensin-1 receptor null mice. | Neuropharmacology 20100101 |
| Anticancer therapeutics that target selenoenzymes: synthesis, characterization, in vitro cytotoxicity, and thioredoxin reductase inhibition of a series of gold(I) complexes containing hydrophilic phosphine ligands. | ChemMedChem 20100101 |
| Photochemical formation and chemistry of long-lived adamantylidene-quinone methides and 2-adamantyl cations. | The Journal of organic chemistry 20100101 |
| Reaching HbA1c goals with saxagliptin in combination with other oral antidiabetic drugs. | Postgraduate medicine 20100101 |
| Antiviral prescriptions to U.S. ambulatory care visits with a diagnosis of influenza before and after high level of adamantane resistance 2005-06 season. | PloS one 20100101 |
| Recent advances on platensimycin: a potential antimicrobial agent. | Current medicinal chemistry 20100101 |
| Host-guest complexation studied by fluorescence correlation spectroscopy: adamantane-cyclodextrin inclusion. | International journal of molecular sciences 20100101 |
| Self-assembly of diamondoid molecules and derivatives (MD simulations and DFT calculations). | International journal of molecular sciences 20100101 |
| Designing inhibitors of M2 proton channel against H1N1 swine influenza virus. | PloS one 20100101 |
| [New blood glucose-lowering drugs in type 2 diabetes: a review of the literature]. | Nederlands tijdschrift voor geneeskunde 20100101 |
| Current advances in anti-influenza therapy. | Current medicinal chemistry 20100101 |
| [A study of the interaction of boraadamantane with liposomes]. | Biofizika 20100101 |
| Saxagliptin: a new dipeptidyl peptidase-4 inhibitor for type 2 diabetes. | Cardiology in review 20100101 |
| A meta-analysis of placebo-controlled clinical trials assessing the efficacy and safety of incretin-based medications in patients with type 2 diabetes. | Pharmacology 20100101 |
| Adaphostin toxicity in a sensitive non-small cell lung cancer model is mediated through Nrf2 signaling and heme oxygenase 1. | Journal of experimental & clinical cancer research : CR 20100101 |
| Weight neutrality with the DPP-4 inhibitor, vildagliptin: mechanistic basis and clinical experience. | Vascular health and risk management 20100101 |
| A comprehensive surveillance of adamantane resistance among human influenza A virus isolated from mainland China between 1956 and 2009. | Antiviral therapy 20100101 |
| Use of the adamantane structure in medicinal chemistry. | Current medicinal chemistry 20100101 |
| A randomized, placebo-controlled, double-blind, prospective trial to evaluate the effect of vildagliptin in new-onset diabetes mellitus after kidney transplantation. | Trials 20100101 |
| Comprehensive assessment of 2009 pandemic influenza A (H1N1) virus drug susceptibility in vitro. | Antiviral therapy 20100101 |
| In vitro susceptibility and virological outcome to darunavir and lopinavir are independent of HIV type-1 subtype in treatment-naive patients. | Antiviral therapy 20100101 |
| [Treatment of asthenic disorders in patients with psychoautonomic syndrome: results of a multicenter study on efficacy and safety of ladasten]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101 |
| [Prospects for using ladasten preparations in patients with irritable bowel syndrome]. | Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20100101 |
| Excellent correlation between cathepsin B inhibition and cytotoxicity for a series of palladacycles. | Dalton transactions (Cambridge, England : 2003) 20091228 |
| Formation and size tuning of colloidal microcapsules via host-guest molecular recognition at the liquid-liquid interface. | Langmuir : the ACS journal of surfaces and colloids 20091215 |
| Exploration of endocrine-disrupting chemicals on estrogen receptor alpha by the agonist/antagonist differential-docking screening (AADS) method: 4-(1-adamantyl)phenol as a potent endocrine disruptor candidate. | Toxicology letters 20091201 |
| Efficacy and safety comparison between the DPP-4 inhibitor vildagliptin and the sulfonylurea gliclazide after two years of monotherapy in drug-naïve patients with type 2 diabetes. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20091201 |
| Insulinotropic actions of nateglinide in type 2 diabetic patients and effects on dipeptidyl peptidase-IV activity and glucose-dependent insulinotropic polypeptide degradation. | European journal of endocrinology 20091201 |
| Synthesis and structural characterization of copper(I) complexes bearing N-methyl-1,3,5-triaza-7-phosphaadamantane (mPTA): cytotoxic activity evaluation of a series of water soluble Cu(I) derivatives containing PTA, PTAH and mPTA ligands. | Journal of inorganic biochemistry 20091201 |
| Saxagliptin added to a thiazolidinedione improves glycemic control in patients with type 2 diabetes and inadequate control on thiazolidinedione alone. | The Journal of clinical endocrinology and metabolism 20091201 |
| Mass spectrometry and UV-VIS spectrophotometry of ruthenium(II) [RuClCp(mPTA)2](OSO2CF3)2 complex in solution. | Rapid communications in mass spectrometry : RCM 20091201 |
| Isolation, structure and biological activities of platensimycin B4 from Streptomyces platensis. | The Journal of antibiotics 20091201 |
| Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice. | The Journal of clinical investigation 20091201 |
| Exploration of the DPP-4 inhibitors with a focus on saxagliptin. | Expert opinion on pharmacotherapy 20091201 |
| Role of the incretin pathway in the pathogenesis of type 2 diabetes mellitus. | Cleveland Clinic journal of medicine 20091201 |
| Total synthesis of platensimycin and related natural products. | Journal of the American Chemical Society 20091125 |
| Construction and charge-transfer complexation of adamantane-based macrocycles and a cage with aromatic ring moieties. | The Journal of organic chemistry 20091120 |
| Modulation of arsenic trioxide-induced apoptosis by genistein and functionally related agents in U937 human leukaemia cells. Regulation by ROS and mitogen-activated protein kinases. | Chemico-biological interactions 20091110 |
| Saxagliptin (Onglyza) for type 2 diabetes. | The Medical letter on drugs and therapeutics 20091102 |
| Cognitive effects of psychotomimetic drugs in rats discriminating number cues. | Psychopharmacology 20091101 |
| Modulation of glycosphingolipid metabolism significantly improves hepatic insulin sensitivity and reverses hepatic steatosis in mice. | Hepatology (Baltimore, Md.) 20091101 |
| Synthesis and biological evaluation of chromium bioorganometallics based on the antibiotic platensimycin lead structure. | ChemMedChem 20091101 |
| Vildagliptin in clinical practice: a review of literature. | Expert opinion on pharmacotherapy 20091101 |
| Genomic events underlying the changes in adamantane resistance among influenza A(H3N2) viruses during 2006-2008. | Influenza and other respiratory viruses 20091101 |
| DPP-4 inhibitors in clinical practice. | Postgraduate medicine 20091101 |
| Insights from investigating the interactions of adamantane-based drugs with the M2 proton channel from the H1N1 swine virus. | Biochemical and biophysical research communications 20091016 |
| Comparison of vildagliptin and thiazolidinedione as add-on therapy in patients inadequately controlled with metformin: results of the GALIANT trial--a primary care, type 2 diabetes study. | Diabetes, obesity & metabolism 20091001 |
| Effect of saxagliptin monotherapy in treatment-naïve patients with type 2 diabetes. | Current medical research and opinion 20091001 |
| Vildagliptin therapy and hypoglycaemia in Muslim type 2 diabetes patients during Ramadan. | International journal of clinical practice 20091001 |
| Development and validation of a liquid chromatography-tandem mass spectrometry method for the determination of ST1926, a novel oral antitumor agent, adamantyl retinoid derivative, in plasma of patients in a Phase I study. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091001 |
| Call for comparative effectiveness research: lowering A1c with sitagliptin, saxagliptin, or cinnamon. | Journal of managed care pharmacy : JMCP 20091001 |
| Prolactin-releasing peptide effects in the rat brain are mediated through the Neuropeptide FF receptor. | The European journal of neuroscience 20091001 |
| Effect of dipeptidyl peptidase-IV (DPP-IV) inhibitor (Vildagliptin) on peripheral nerves in streptozotocin-induced diabetic rats. | Archives of medical research 20091001 |
| A novel class of highly potent multidrug resistance reversal agents: disubstituted adamantyl derivatives. | Bioorganic & medicinal chemistry letters 20090915 |
| Kinetic study of neuropeptide Y (NPY) proteolysis in blood and identification of NPY3-35: a new peptide generated by plasma kallikrein. | The Journal of biological chemistry 20090911 |
| Common binding site for externally and internally applied AMPA receptor channel blockers. | Journal of molecular neuroscience : MN 20090901 |
| The efficacy and safety of saxagliptin when added to metformin therapy in patients with inadequately controlled type 2 diabetes with metformin alone. | Diabetes care 20090901 |
| The extracellular calcium-sensing receptor is expressed in the cumulus-oocyte complex in mammals and modulates oocyte meiotic maturation. | Reproduction (Cambridge, England) 20090901 |
| Angiotensin-converting enzyme and dipeptidyl peptidase IV inhibitors: an increased risk of angioedema. | Hypertension (Dallas, Tex. : 1979) 20090901 |
| Dipeptidyl peptidase-IV inhibitor use associated with increased risk of ACE inhibitor-associated angioedema. | Hypertension (Dallas, Tex. : 1979) 20090901 |
| Dynamics of antiviral-resistant influenza viruses in the Netherlands, 2005-2008. | Antiviral research 20090901 |
| Saxagliptin added to a submaximal dose of sulphonylurea improves glycaemic control compared with uptitration of sulphonylurea in patients with type 2 diabetes: a randomised controlled trial. | International journal of clinical practice 20090901 |
| Electron microscopical study to assess the in vitro effects of the synthetic trioxolane OZ78 against the liver fluke, Fasciola hepatica. | Parasitology 20090901 |
| FDA approves saxagliptin for type 2 diabetes. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090901 |
| Defining the importance of daily glycemic control and implications for type 2 diabetes management. | Postgraduate medicine 20090901 |
| Efficient guest inclusion by β-cyclodextrin attached to the ends of DNA oligomers upon hybridization to various DNA conjugates. | Bioconjugate chemistry 20090819 |
| Large footprint pyrene chromophores anchored to planar and colloidal metal oxide thin films. | Langmuir : the ACS journal of surfaces and colloids 20090818 |
| Systematic studies using 2-(1-adamantylethynyl)pyrimidine-5-carbaldehyde as a starting material in Soai's asymmetric autocatalysis. | Chemistry (Weinheim an der Bergstrasse, Germany) 20090817 |
| Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis. | Bioorganic & medicinal chemistry letters 20090815 |
| Isoplatensimycin: Synthesis and biological evaluation. | Bioorganic & medicinal chemistry letters 20090815 |
| Access to flavones via a microwave-assisted, one-pot Sonogashira-carbonylation-annulation reaction. | Organic letters 20090806 |
| The effect of a full agonist/antagonist of the D1 receptor on locomotor activity, sensorimotor gating and cognitive function in dizocilpine-treated rats. | The international journal of neuropsychopharmacology 20090801 |
| Comparison of vildagliptin and metformin monotherapy in elderly patients with type 2 diabetes: a 24-week, double-blind, randomized trial. | Diabetes, obesity & metabolism 20090801 |
| Adaptability and selectivity of human peroxisome proliferator-activated receptor (PPAR) pan agonists revealed from crystal structures. | Acta crystallographica. Section D, Biological crystallography 20090801 |
| Mechanism of action of inhibitors of dipeptidyl-peptidase-4 (DPP-4). | Best practice & research. Clinical endocrinology & metabolism 20090801 |
| Clinical results of treating type 2 diabetic patients with sitagliptin, vildagliptin or saxagliptin--diabetes control and potential adverse events. | Best practice & research. Clinical endocrinology & metabolism 20090801 |
| Susceptibility of antiviral drugs against 2009 influenza A (H1N1) virus. | Biochemical and biophysical research communications 20090731 |
| Unexpected fluorescent behavior of a 4-amino-1,8-naphthalimide derived beta-cyclodextrin: conformation analysis and sensing properties. | Chemical communications (Cambridge, England) 20090721 |
| A novel benzimidazole analogue inhibits the hypoxia-inducible factor (HIF)-1 pathway. | Biochemical and biophysical research communications 20090717 |
| The dynamic side of the Hofmeister effect: a single-molecule nanopore study of specific complex formation. | Chemphyschem : a European journal of chemical physics and physical chemistry 20090713 |
| Investigation into adamantane-based M2 inhibitors with FB-QSAR. | Medicinal chemistry (Shariqah (United Arab Emirates)) 20090701 |
| Stereoelectronic effect for the selectivity in C-H insertion of alkylidene carbenes and its application to the synthesis of platensimycin. | Journal of the American Chemical Society 20090624 |
| Targeting angiogenesis via a c-Myc/hypoxia-inducible factor-1alpha-dependent pathway in multiple myeloma. | Cancer research 20090615 |
| The origin and global emergence of adamantane resistant A/H3N2 influenza viruses. | Virology 20090605 |
| Attenuation of cisplatin nephrotoxicity by inhibition of soluble epoxide hydrolase. | Cell biology and toxicology 20090601 |
| Highly twisted adamantyl arotinoids: synthesis, antiproliferative effects and RXR transactivation profiles. | European journal of medicinal chemistry 20090601 |
| Pharmacokinetics of the dipeptidyl peptidase 4 inhibitor saxagliptin in rats, dogs, and monkeys and clinical projections. | Drug metabolism and disposition: the biological fate of chemicals 20090601 |
| Bradykinin inhibits the transient outward K+ current in mouse Schwann cells via the cAMP/PKA pathway. | American journal of physiology. Cell physiology 20090601 |
| Neurotensin inhibition of GABAergic transmission via mGluR-induced endocannabinoid signalling in rat periaqueductal grey. | The Journal of physiology 20090601 |
| Long-term 2-year safety and efficacy of vildagliptin compared with rosiglitazone in drug-naïve patients with type 2 diabetes mellitus. | Diabetes, obesity & metabolism 20090601 |
| Soluble epoxide inhibition is protective against cerebral ischemia via vascular and neural protection. | The American journal of pathology 20090601 |
| SHP and Sin3A expression are essential for adamantyl-substituted retinoid-related molecule-mediated nuclear factor-kappaB activation, c-Fos/c-Jun expression, and cellular apoptosis. | Molecular cancer therapeutics 20090601 |
| Extrapolating from sequence--the 2009 H1N1 'swine' influenza virus. | Nature biotechnology 20090601 |
| Comparison of vildagliptin and pioglitazone in patients with type 2 diabetes inadequately controlled with metformin. | Diabetes, obesity & metabolism 20090601 |
| Saxagliptin given in combination with metformin as initial therapy improves glycaemic control in patients with type 2 diabetes compared with either monotherapy: a randomized controlled trial. | Diabetes, obesity & metabolism 20090601 |
| [Pharmacological sheet. Vildagliptin, oral administration (GALVUS)]. | Journal de pharmacie de Belgique 20090601 |
| Altering the electronic properties of diamondoids through encapsulating small particles. | Journal of physics. Condensed matter : an Institute of Physics journal 20090527 |
| Rapid spread of drug-resistant influenza A viruses in the Basque Country, northern Spain, 2000-1 to 2008-9. | Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20090521 |
| Synaptic scaling requires the GluR2 subunit of the AMPA receptor. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090520 |
| Synthesis and evaluation of carbamate prodrugs of SQ109 as antituberculosis agents. | Bioorganic & medicinal chemistry letters 20090515 |
| Mechanism of drug inhibition and drug resistance of influenza A M2 channel. | Proceedings of the National Academy of Sciences of the United States of America 20090505 |
| Oxidative stress by targeted agents promotes cytotoxicity in hematologic malignancies. | Antioxidants & redox signaling 20090501 |
| Efficacy and tolerability of vildagliptin in patients with type 2 diabetes inadequately controlled with metformin monotherapy. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20090501 |
| An isotropic chemical shift-chemical shift anisotropic correlation experiment using discrete magic angle turning. | Journal of magnetic resonance (San Diego, Calif. : 1997) 20090501 |
| Vildagliptin plus metformin combination therapy provides superior glycaemic control to individual monotherapy in treatment-naive patients with type 2 diabetes mellitus. | Diabetes, obesity & metabolism 20090501 |
| Influenza virus resistance to antiviral agents: a plea for rational use. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090501 |
| Beta-cyclodextrin-modified CdSe/ZnS quantum dots for sensing and chiroselective analysis. | Nano letters 20090501 |
| Study of the pharmacokinetic interaction of vildagliptin and metformin in patients with type 2 diabetes. | Current medical research and opinion 20090501 |
| Islet enhancer vildagliptin: a powerful partner with metformin for the treatment of patients with type 2 diabetes. | Diabetes, obesity & metabolism 20090501 |
| The scientific evidence: vildagliptin and the benefits of islet enhancement. | Diabetes, obesity & metabolism 20090501 |
| Translating science into clinical practice: focus on vildagliptin in combination with metformin. | Diabetes, obesity & metabolism 20090501 |
| [The value of incretin based therapies]. | Deutsche medizinische Wochenschrift (1946) 20090501 |
| Saxagliptin: a new dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes. | Advances in therapy 20090501 |
| Changes in CREB (SER133) content and DNA-binding activity of transcriptional factors in rat brain cells against the background of ladasten exposure. | Bulletin of experimental biology and medicine 20090501 |
| A soluble sulfogalactosyl ceramide mimic promotes Delta F508 CFTR escape from endoplasmic reticulum associated degradation. | Chemistry & biology 20090424 |
| Highly enantioselective organocatalytic oxidative kinetic resolution of secondary alcohols using chirally modified AZADOs. | Organic letters 20090416 |
| Synthesis and pharmacological evaluation of (2-oxaadamant-1-yl)amines. | Bioorganic & medicinal chemistry 20090415 |
| Exploring a pocket for polycycloaliphatic groups in the CXCR3 receptor with the aid of a modular synthetic strategy. | Bioorganic & medicinal chemistry letters 20090415 |
| Vibrational analysis as a powerful tool in structure elucidation of polyarsenicals: a DFT-based investigation of arsenicin A. | Physical chemistry chemical physics : PCCP 20090414 |
| [Incretin related agents for treatment of diabetes mellitus]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20090410 |
| Ionic recognition by 7-nitro-1,3,5-triaza adamantane: first thermodynamic study. | The journal of physical chemistry. B 20090409 |
| Wrenchnolol derivative optimized for gene activation in cells. | Journal of the American Chemical Society 20090408 |
| Vildagliptin enhances islet responsiveness to both hyper- and hypoglycemia in patients with type 2 diabetes. | The Journal of clinical endocrinology and metabolism 20090401 |
| Mechanism of action of species-selective P2X(7) receptor antagonists. | British journal of pharmacology 20090401 |
| Perspectives on influenza virus infection. | Pediatrics and neonatology 20090401 |
| Synthetic studies on siphonariid polypropionates: synthesis and isomerization of the caloundrin B trioxaadamantane ring system. | Organic letters 20090319 |
| Synthesis and biological evaluation of platensimycin analogs. | Bioorganic & medicinal chemistry letters 20090315 |
| Adamantane derivatives of thiazolyl-N-substituted amide, as possible non-steroidal anti-inflammatory agents. | European journal of medicinal chemistry 20090301 |
| Evolution of drug resistance in multiple distinct lineages of H5N1 avian influenza. | Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20090301 |
| Ethanol withdrawal provokes opening of the mitochondrial membrane permeability transition pore in an estrogen-preventable manner. | The Journal of pharmacology and experimental therapeutics 20090301 |
| Absorption, metabolism, and excretion of [14C]vildagliptin, a novel dipeptidyl peptidase 4 inhibitor, in humans. | Drug metabolism and disposition: the biological fate of chemicals 20090301 |
| Disposition of vildagliptin, a novel dipeptidyl peptidase 4 inhibitor, in rats and dogs. | Drug metabolism and disposition: the biological fate of chemicals 20090301 |
| Dipeptidyl-peptidase-IV inhibition augments postprandial lipid mobilization and oxidation in type 2 diabetic patients. | The Journal of clinical endocrinology and metabolism 20090301 |
| Human influenza A viruses isolated in South America: genetic relations, adamantane resistance and vaccine strain match. | Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20090301 |
| Studies on depigmenting activities of dihydroxyl benzamide derivatives containing adamantane moiety. | Bioorganic & medicinal chemistry letters 20090301 |
| DPP4 inhibitors: from sitagliptin monotherapy to the new alogliptin-pioglitazone combination therapy. | Advances in therapy 20090301 |
| Saxagliptin: a new DPP-4 inhibitor for the treatment of type 2 diabetes mellitus. | Advances in therapy 20090301 |
| Soluble epoxide hydrolase: a new target for cardioprotection. | Current opinion in investigational drugs (London, England : 2000) 20090301 |
| [Vildagliptin (Galvus) and fixed combination vildagliptine-metformin (Eucreas) in the treatment of type 2 diabetes]. | Revue medicale de Liege 20090301 |
| Antiviral resistance in influenza viruses circulating in Central and South America based on the detection of established genetic markers. | Influenza and other respiratory viruses 20090301 |
| Pseudo-capsule assemblies characterized by 19F NMR techniques. | Journal of the American Chemical Society 20090225 |
| Design and synthesis of 1,2-annulated adamantane piperidines with anti-influenza virus activity. | Bioorganic & medicinal chemistry 20090215 |
| Total synthesis of (-)-platensimycin, a novel antibacterial agent. | The Journal of organic chemistry 20090206 |
| Efficient cross-polarization using a composite 0 degrees pulse for NMR studies on static solids. | Journal of magnetic resonance (San Diego, Calif. : 1997) 20090201 |
| Reduction of glycosphingolipid biosynthesis stimulates biliary lipid secretion in mice. | Hepatology (Baltimore, Md.) 20090201 |
| Vildagliptin dose-dependently improves glycemic control in Japanese patients with type 2 diabetes mellitus. | Diabetes research and clinical practice 20090201 |
| Fifty-two-week efficacy and safety of vildagliptin vs. glimepiride in patients with type 2 diabetes mellitus inadequately controlled on metformin monotherapy. | Diabetes, obesity & metabolism 20090201 |
| Drug evaluation: vildagliptin-metformin single-tablet combination. | Advances in therapy 20090201 |
| In vivo profiling of DPP4 inhibitors reveals alterations in collagen metabolism and accumulation of an amyloid peptide in rat plasma. | Biochemical pharmacology 20090115 |
| Synthesis and anti-HIV studies of 2- and 3-adamantyl-substituted thiazolidin-4-ones. | European journal of medicinal chemistry 20090101 |
| Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto-Kakizaki rats. | Clinical science (London, England : 1979) 20090101 |
| Adamantane/beta-cyclodextrin affinity biosensors based on single-walled carbon nanotubes. | Biosensors & bioelectronics 20090101 |
| Pharmacokinetics and pharmacodynamics of vildagliptin in healthy Chinese volunteers. | Journal of clinical pharmacology 20090101 |
| Inhibition of dipeptidyl peptidase-4 by vildagliptin during glucagon-like Peptide 1 infusion increases liver glucose uptake in the conscious dog. | Diabetes 20090101 |
| Dipeptidyl peptidase-4 inhibition by vildagliptin and the effect on insulin secretion and action in response to meal ingestion in type 2 diabetes. | Diabetes care 20090101 |
| Treatment with the dipeptidyl peptidase-4 inhibitor vildagliptin improves fasting islet-cell function in subjects with type 2 diabetes. | The Journal of clinical endocrinology and metabolism 20090101 |
| Polycyclic compounds: ideal drug scaffolds for the design of multiple mechanism drugs? | Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20090101 |
| Emerging drug candidates of dipeptidyl peptidase IV (DPP IV) inhibitor class for the treatment of Type 2 Diabetes. | Current drug targets 20090101 |
| Incretin mimetics and DPP-4 inhibitors: new approach to treatment of type 2 diabetes mellitus. | Mymensingh medical journal : MMJ 20090101 |
| Ca(2+) permeable AMPA receptor induced long-term potentiation requires PI3/MAP kinases but not Ca/CaM-dependent kinase II. | PloS one 20090101 |
| Efforts towards the identification of simpler platensimycin analogues--the total synthesis of oxazinidinyl platensimycin. | Chemistry (Weinheim an der Bergstrasse, Germany) 20090101 |
| Reducing glycosphingolipid content in adipose tissue of obese mice restores insulin sensitivity, adipogenesis and reduces inflammation. | PloS one 20090101 |
| [Effects of antiparkinsonian drug hemantane on the level and metabolism of biogenic monoamines in brain structures of C57BL/6 mice]. | Eksperimental'naia i klinicheskaia farmakologiia 20090101 |
| Mimicking natural globular structures with rigid scaffolds based on adamantane. | Advances in experimental medicine and biology 20090101 |
| A supramolecular approach for preparation of size-controlled nanoparticles. | Angewandte Chemie (International ed. in English) 20090101 |
| [Effects of novel antiviral agents on HIV-1 replication]. | Voprosy virusologii 20090101 |
| [Ladasten, the new drug with psychostimulant and anxiolytic actions in treatment of neurasthenia (results of the comparative clinical study with placebo)]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101 |
| Rhodium-catalyzed asymmetric enyne cycloisomerization of terminal alkynes and formal total synthesis of (-)-platensimycin. | Angewandte Chemie (International ed. in English) 20090101 |
| Platensimycin activity against mycobacterial beta-ketoacyl-ACP synthases. | PloS one 20090101 |
| [Effect of ladasten on the psychophysiological parameters of healthy volunteers]. | Eksperimental'naia i klinicheskaia farmakologiia 20090101 |
| New therapeutic horizons: mapping the future of glycemic control with incretin-based therapy. | The Diabetes educator 20090101 |
| A concise ring-expansion route to the compact core of platensimycin. | Angewandte Chemie (International ed. in English) 20090101 |
| Prasugrel hydrochloride, dronedarone, and saxagliptin hydrochloride. | Journal of the American Pharmacists Association : JAPhA 20090101 |
| K ATP channels in pig and human intracranial arteries. | European journal of pharmacology 20081228 |
| DPP4 inhibitors for diabetes--what next? | Biochemical pharmacology 20081215 |
| Distribution and dynamics of adamantanes in a lipid bilayer. | Biophysical journal 20081215 |
| Incretin-based therapies in type 2 diabetes: a review of clinical results. | Diabetes research and clinical practice 20081215 |
| New water-soluble azido- and derived tetrazolato-platinum(II) complexes with PTA. Easy metal-mediated synthesis and isolation of 5-substituted tetrazoles. | Dalton transactions (Cambridge, England : 2003) 20081214 |
| Construction of the adamantane core of plukenetione-type polycyclic polyprenylated acylphloroglucinols. | The Journal of organic chemistry 20081205 |
| Electronic and steric effects in binding of deep cavitands. | Organic letters 20081204 |
| Efficacy and safety of vildagliptin monotherapy during 2-year treatment of drug-naïve patients with type 2 diabetes: comparison with metformin. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20081201 |
| Characterization of N-(adamantan-1-ylmethyl)-5-[(3R-amino-pyrrolidin-1-yl)methyl]-2-chloro-benzamide, a P2X7 antagonist in animal models of pain and inflammation. | The Journal of pharmacology and experimental therapeutics 20081201 |
| Combination of the dipeptidyl peptidase IV inhibitor LAF237 [(S)-1-[(3-hydroxy-1-adamantyl)ammo]acetyl-2-cyanopyrrolidine] with the angiotensin II type 1 receptor antagonist valsartan [N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl]-L-valine] enhances pancreatic islet morphology and function in a mouse model of type 2 diabetes. | The Journal of pharmacology and experimental therapeutics 20081201 |
| Inhibition of soluble epoxide hydrolase does not protect against endotoxin-mediated hepatic inflammation. | The Journal of pharmacology and experimental therapeutics 20081201 |
| Comparisons of the influenza virus A M2 channel binding affinities, anti-influenza virus potencies and NMDA antagonistic activities of 2-alkyl-2-aminoadamantanes and analogues. | Bioorganic & medicinal chemistry letters 20081201 |
| Saxagliptin, a dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. | IDrugs : the investigational drugs journal 20081201 |
| Incretin-based therapies: a new potential treatment approach to overcome clinical inertia in type 2 diabetes. | Acta bio-medica : Atenei Parmensis 20081201 |
| Combination therapy with DPP-4 inhibitors and pioglitazone in type 2 diabetes: theoretical consideration and therapeutic potential. | Vascular health and risk management 20081201 |
| Vildagliptin: a new oral treatment for type 2 diabetes mellitus. | Vascular health and risk management 20081201 |
| Cytochrome P450-mediated metabolism of N-(2-methoxyphenyl)-hydroxylamine, a human metabolite of the environmental pollutants and carcinogens o-anisidine and o-nitroanisole. | Interdisciplinary toxicology 20081201 |
| Cu(I) complexes bearing the new sterically demanding and coordination flexible tris(3-phenyl-1-pyrazolyl)methanesulfonate ligand and the water-soluble phosphine 1,3,5-triaza-7-phosphaadamantane or related ligands. | Inorganic chemistry 20081103 |
| Effects of vildagliptin on glucose control in patients with type 2 diabetes inadequately controlled with a sulphonylurea. | Diabetes, obesity & metabolism 20081101 |
| The effect of dipeptidyl peptidase-4 inhibition on gastric volume, satiation and enteroendocrine secretion in type 2 diabetes: a double-blind, placebo-controlled crossover study. | Clinical endocrinology 20081101 |
| Evidence that vildagliptin attenuates deterioration of glycaemic control during 2-year treatment of patients with type 2 diabetes and mild hyperglycaemia. | Diabetes, obesity & metabolism 20081101 |
| Adverse effects of dipeptidyl peptidases 8 and 9 inhibition in rodents revisited. | Diabetes, obesity & metabolism 20081101 |
| Adamantane resistance in influenza A(H1) viruses increased in 2007 in South East Asia but decreased in Australia and some other countries. | Antiviral research 20081101 |
| Soluble epoxide hydrolase inhibition and gene deletion are protective against myocardial ischemia-reperfusion injury in vivo. | American journal of physiology. Heart and circulatory physiology 20081101 |
| Dipeptidyl peptidase-4 as a new target of action for type 2 diabetes mellitus: a systematic review. | Cardiology clinics 20081101 |
| [Future therapeutic options and their indications: transplantation and the possibilities of regenerative therapy for diabetes type 1]. | MMW Fortschritte der Medizin 20081030 |
| Isolation, structure and fatty acid synthesis inhibitory activities of platensimycin B1-B3 from Streptomyces platensis. | Chemical communications (Cambridge, England) 20081028 |
| X-ray crystal structure of human heme oxygenase-1 in complex with 1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone: a common binding mode for imidazole-based heme oxygenase-1 inhibitors. | Journal of medicinal chemistry 20081009 |
| Monoprotection of diols as a key step for the selective synthesis of unequally disubstituted diamondoids (nanodiamonds). | The Journal of organic chemistry 20081003 |
| Effect of vildagliptin on glucagon concentration during meals in patients with type 1 diabetes. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20081001 |
| Design, synthesis, and biological evaluation of platensimycin analogues with varying degrees of molecular complexity. | Journal of the American Chemical Society 20081001 |
| Does Gd@C82 have an anomalous endohedral structure? Synthesis and single crystal X-ray structure of the carbene adduct. | Journal of the American Chemical Society 20081001 |
| Control of an outbreak due to an adamantane-resistant strain of influenza A (H3N2) in a chronic care facility. | Infection 20081001 |
| [Sitagliptin. DPP-4 inhibitors as a useful extension of oral diabetes therapy?]. | Deutsche medizinische Wochenschrift (1946) 20081001 |
| Structural analysis of binding of a diamantoid substrate to cytochrome P450 2B4: possible role of Arg 133 in modulation of function and activity of this enzyme. | Neuro endocrinology letters 20081001 |
| Vildagliptin and vildagliptin/metformin: new drug. Same limited efficacy as sitagliptin in type 2 diabetes. | Prescrire international 20081001 |
| Adamantyl-substituted retinoid-derived molecules that interact with the orphan nuclear receptor small heterodimer partner: effects of replacing the 1-adamantyl or hydroxyl group on inhibition of cancer cell growth, induction of cancer cell apoptosis, and inhibition of SRC homology 2 domain-containing protein tyrosine phosphatase-2 activity. | Journal of medicinal chemistry 20080925 |
| Stereocontrolled formal synthesis of (+/-)-platensimycin. | Organic letters 20080918 |
| Novel 2,4-methanoadamantane-benzazepine by domino photochemistry of N-(1-adamantyl)phthalimide. | Organic letters 20080918 |
| Design, synthesis, and bioactivity of putative tubulin ligands with adamantane core. | Bioorganic & medicinal chemistry letters 20080915 |
| Inhibition of IkappaB kinase-beta and anticancer activities of novel chalcone adamantyl arotinoids. | Journal of medicinal chemistry 20080911 |
| Crystal structures of rat vitamin D receptor bound to adamantyl vitamin D analogs: structural basis for vitamin D receptor antagonism and partial agonism. | Journal of medicinal chemistry 20080911 |
| Study of secondary relaxation in disordered plastic crystals of isocyanocyclohexane, cyanocyclohexane, and 1-cyanoadamantane. | The Journal of chemical physics 20080907 |
| Recognition of guests by water-stabilized cavitand hosts. | Organic letters 20080904 |
| A simple, efficient, and enantiocontrolled synthesis of a near-structural mimic of platensimycin. | Organic letters 20080904 |
| Robust improvements in fasting and prandial measures of beta-cell function with vildagliptin in drug-naïve patients: analysis of pooled vildagliptin monotherapy database. | Diabetes, obesity & metabolism 20080901 |
| The glucosylceramide synthase inhibitor N-(5-adamantane-1-yl-methoxy-pentyl)-deoxynojirimycin induces sterol regulatory element-binding protein-regulated gene expression and cholesterol synthesis in HepG2 cells. | The Journal of pharmacology and experimental therapeutics 20080901 |
| Cloning and expression of the L-1-amino-2-propanol dehydrogenase gene from Rhodococcus erythropolis, and its application to double chiral compound production. | Applied microbiology and biotechnology 20080901 |
| Atypical retinoids ST1926 and CD437 are S-phase-specific agents causing DNA double-strand breaks: significance for the cytotoxic and antiproliferative activity. | Molecular cancer therapeutics 20080901 |
| Rat cytochromes P450 oxidize 3-aminobenzanthrone, a human metabolite of the carcinogenic environmental pollutant 3-nitrobenzanthrone. | Interdisciplinary toxicology 20080901 |
| Investigations on the 4-quinolone-3-carboxylic acid motif. 2. Synthesis and structure-activity relationship of potent and selective cannabinoid-2 receptor agonists endowed with analgesic activity in vivo. | Journal of medicinal chemistry 20080828 |
| Synthesis of somatostatin analogues containing C-terminal adamantane and their antiproliferative properties. | Journal of medicinal chemistry 20080828 |
| Construction and micellization of a noncovalent double hydrophilic block copolymer. | Chemical communications (Cambridge, England) 20080828 |
| DNA structural distortions induced by ruthenium-arene anticancer compounds. | Journal of the American Chemical Society 20080820 |
| Toward the discovery of potent inhibitors of botulinum neurotoxin A: development of a robust LC MS based assay operational from low to subnanomolar enzyme concentrations. | Chemical communications (Cambridge, England) 20080814 |
| Gamma-cyclodextrin forms a highly compressible complex with 1-adamantanecarboxylic acid. | The journal of physical chemistry. B 20080807 |
| Efficacy and tolerability of vildagliptin in drug-naïve patients with type 2 diabetes and mild hyperglycaemia*. | Diabetes, obesity & metabolism 20080801 |
| Adamantane resistance in circulating human influenza A viruses from Alberta, Canada (1970-2007). | Antiviral research 20080801 |
| Incretin mimetics and dipeptidyl peptidase-4 inhibitors: innovative treatment therapies for type 2 diabetes. | Arquivos brasileiros de endocrinologia e metabologia 20080801 |
| Emerging role of dipeptidyl peptidase-4 inhibitors in the management of type 2 diabetes. | Vascular health and risk management 20080801 |
| Theoretical studies on the structure and symmetry of the transmembrane region of glutamatergic GluR5 receptor. | Journal of medicinal chemistry 20080710 |
| Synthesis, characterization, and in vitro cytotoxicity of some gold(I) and trans platinum(II) thionate complexes containing water-soluble PTA and DAPTA ligands. X-ray crystal structures of [Au(SC4H3N2)(PTA)], trans-[Pt(SC4H3N2)2(PTA)2], trans-[Pt(SC5H4N)2(PTA)2], and trans-[Pt(SC5H4N)2(DAPTA)2]. | Inorganic chemistry 20080707 |
| Neuropeptide FF receptors antagonist, RF9, attenuates opioid-evoked hypothermia in mice. | Peptides 20080701 |
| Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials. | Current opinion in clinical nutrition and metabolic care 20080701 |
| From the bench to the bedside: dipeptidyl peptidase IV inhibitors, a new class of oral antihyperglycemic agents. | Current opinion in drug discovery & development 20080701 |
| Three new drugs for type 2 diabetes. | Drug and therapeutics bulletin 20080701 |
| DPP4 inhibitors: a new approach in diabetes treatment. | Advances in therapy 20080701 |
| Evaluation of pharmacokinetic and pharmacodynamic interaction between the dipeptidyl peptidase IV inhibitor vildagliptin, glyburide and pioglitazone in patients with Type 2 diabetes. | International journal of clinical pharmacology and therapeutics 20080701 |
| Peripheral and central routes of administration of quaternary ammonium compound IEM-1460 are equally potent in reducing the severity of nicotine-induced seizures in mice. | Bulletin of experimental biology and medicine 20080701 |
| Local correlation domains for coupled cluster theory: optical rotation and magnetic-field perturbations. | Physical chemistry chemical physics : PCCP 20080621 |
| Bioconjugation of alkaline phosphatase to mechanically processed, aqueous suspendible electrospun polymer nanofibers for use in chemiluminescent detection assays. | Macromolecular bioscience 20080611 |
| Selective fluorination of adamantanes by an electrochemical method. | The Journal of organic chemistry 20080606 |
| Detection of adamantane-resistant influenza on a microarray. | Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20080601 |
| Insights into homonuclear decoupling from efficient numerical simulation: techniques and examples. | Journal of magnetic resonance (San Diego, Calif. : 1997) 20080601 |
| Sustained efficacy and reduced hypoglycemia during one year of treatment with vildagliptin added to insulin in patients with type 2 diabetes mellitus. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20080601 |
| Effects of the selective neurotensin antagonist SR 142948A on 3,4-methylenedioxymethamphetamine-induced behaviours in mice. | Neuropharmacology 20080601 |
| Effects of the selective EET antagonist, 14,15-EEZE, on cardioprotection produced by exogenous or endogenous EETs in the canine heart. | American journal of physiology. Heart and circulatory physiology 20080601 |
| Synthesis of platensimycin analogues and their antibiotic potency. | Archiv der Pharmazie 20080601 |
| Effect of food on the pharmacokinetics of a vildagliptin/metformin (50/1000 mg) fixed-dose combination tablet in healthy volunteers. | Current medical research and opinion 20080601 |
| Incretin mimetics and dipeptidyl peptidase 4 inhibitors in clinical trials for the treatment of type 2 diabetes. | Expert opinion on investigational drugs 20080601 |
| Combination treatment in the management of type 2 diabetes: focus on vildagliptin and metformin as a single tablet. | Vascular health and risk management 20080601 |
| 2-amino-1,3-thiazol-4(5H)-ones as potent and selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: enzyme-ligand co-crystal structure and demonstration of pharmacodynamic effects in C57Bl/6 mice. | Journal of medicinal chemistry 20080522 |
| A bridging hexazene (RNNNNNNR) ligand from reductive coupling of azides. | Journal of the American Chemical Society 20080514 |
| A simple method for preparation of molecularly imprinted nanofiber materials with signal transduction ability. | Chemical communications (Cambridge, England) 20080507 |
| Design, synthesis, conformational and membrane ion transport studies of proline-adamantane hybrid cyclic depsipeptides. | Biopolymers 20080501 |
| Neonatal tactile stimulation enhances spatial working memory, prefrontal long-term potentiation, and D1 receptor activation in adult rats. | Neurobiology of learning and memory 20080501 |
| Fasciola hepatica: Surface tegumental responses to in vitro and in vivo treatment with the experimental fasciolicide OZ78. | Experimental parasitology 20080501 |
| Selectively increased trace conditioning under the neurotensin agonist PD 149163 in an aversive procedure in which SR 142948A was without intrinsic effect. | Journal of psychopharmacology (Oxford, England) 20080501 |
| K(ATP) channel expression and pharmacological in vivo and in vitro studies of the K(ATP) channel blocker PNU-37883A in rat middle meningeal arteries. | British journal of pharmacology 20080501 |
| Glucose-lowering activity of the dipeptidyl peptidase-4 inhibitor saxagliptin in drug-naive patients with type 2 diabetes. | Diabetes, obesity & metabolism 20080501 |
| Emergence of adamantane-resistant influenza A(H3N2) viruses in Hong Kong between 1997 and 2006. | Journal of medical virology 20080501 |
| Structure and semisynthesis of platensimide A, produced by Streptomyces platensis. | Organic letters 20080501 |
| Involvement of ionotropic glutamate receptors in the appearance of arecoline tremor in mice. | Neuroscience and behavioral physiology 20080501 |
| Soluble epoxide hydrolase inhibitor, AUDA, prevents early salt-sensitive hypertension. | Frontiers in bioscience : a journal and virtual library 20080501 |
| Dipeptidyl peptidase IV (DPP IV) and related molecules in type 2 diabetes. | Frontiers in bioscience : a journal and virtual library 20080501 |
| Bioequivalence of vildagliptin/metformin fixed-dose combination tablets and a free combination of vildagliptin and metformin in healthy subjects. | International journal of clinical pharmacology and therapeutics 20080501 |
| In vivo neurochemical effects of the NR2B selective NMDA receptor antagonist CR 3394 in 6-hydroxydopamine lesioned rats. | European journal of pharmacology 20080428 |
| Dipeptidyl peptidase-4 (DPP-4) inhibitors for type 2 diabetes mellitus. | The Cochrane database of systematic reviews 20080416 |
| Inhibition of neuropeptide FF (NPFF)-induced hypothermia and anti-morphine analgesia by RF9, a new selective NPFF receptors antagonist. | Regulatory peptides 20080410 |
| Comparison of vildagliptin and acarbose monotherapy in patients with Type 2 diabetes: a 24-week, double-blind, randomized trial. | Diabetic medicine : a journal of the British Diabetic Association 20080401 |
| Novel combination treatment of type 2 diabetes DPP-4 inhibition + metformin. | Vascular health and risk management 20080401 |
| Design, synthesis, and trypanocidal activity of new aminoadamantane derivatives. | Journal of medicinal chemistry 20080313 |
| The novel cannabinoid CB1 receptor neutral antagonist AM4113 suppresses food intake and food-reinforced behavior but does not induce signs of nausea in rats. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080301 |
| The effect of age, gender, and body mass index on the pharmacokinetics and pharmacodynamics of vildagliptin in healthy volunteers. | British journal of clinical pharmacology 20080301 |
| Characterization of the two major CYP450 metabolites of ozonide (1,2,4-trioxolane) OZ277. | Bioorganic & medicinal chemistry letters 20080301 |
| Islet cell function is as interesting as insulin resistance for T2DM treatment options. | International journal of clinical practice. Supplement 20080301 |
| The islet enhancer vildagliptin: mechanisms of improved glucose metabolism. | International journal of clinical practice. Supplement 20080301 |
| Vildagliptin: clinical trials programme in monotherapy and combination therapy for type 2 diabetes. | International journal of clinical practice. Supplement 20080301 |
| SQ109. | Tuberculosis (Edinburgh, Scotland) 20080301 |
| Effect of antiparkinsonian drug himantane on the content of dopamine transporter DAT protein in rat striatum and cultured pheochromocytoma PC-12 cells. | Bulletin of experimental biology and medicine 20080301 |
| Inhibition of multidrug resistance by adamantylgb3, a globotriaosylceramide analog. | The Journal of biological chemistry 20080222 |
| Orally active esters of dihydroartemisinin: Synthesis and antimalarial activity against multidrug-resistant Plasmodium yoelii in mice. | Bioorganic & medicinal chemistry letters 20080215 |
| The discovery of adamantyl-derived, inhaled, long acting beta(2)-adrenoreceptor agonists. | Bioorganic & medicinal chemistry letters 20080215 |
| Measurements of islet function and glucose metabolism with the dipeptidyl peptidase 4 inhibitor vildagliptin in patients with type 2 diabetes. | The Journal of clinical endocrinology and metabolism 20080201 |
| Synthesis, in vitro and in vivo characterization of (64)Cu(I) complexes derived from hydrophilic tris(hydroxymethyl)phosphane and 1,3,5-triaza-7-phosphaadamantane ligands. | Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20080201 |
| SAR-oriented discovery of peroxisome proliferator-activated receptor pan agonist with a 4-adamantylphenyl group as a hydrophobic tail. | Bioorganic & medicinal chemistry letters 20080201 |
| Rigid multivalent scaffolds based on adamantane. | The Journal of organic chemistry 20080201 |
| Involvement of DPP-IV catalytic residues in enzyme-saxagliptin complex formation. | Protein science : a publication of the Protein Society 20080201 |
| Cocrystallization of adamantane-1,3-dicarboxylic acid and 4,4'-bipyridine. | Acta crystallographica. Section C, Crystal structure communications 20080201 |
| Is adamantane a suitable substituent to pre-organize the acid orientation in E-selectin antagonists? | Bioorganic & medicinal chemistry 20080115 |
| Diastereomerically enriched analogues of the water-soluble phosphine PTA. Synthesis of phenyl(1,3,5-triaza-7-phosphatricyclo[3.3.1.1(3,7)]dec-6-yl)methanol (PZA) and the sulfide PZA(S) and X-ray crystal structures of the oxide PZA(O) and [Cp*IrCl(2)(PZA)]. | Inorganic chemistry 20080107 |
| Water-soluble and stable dinitrogen phosphine complexes trans-[ReCl(N2)(PTA-H)n(PTA)4-n]n+ (n = 0-4), the first with 1,3,5-triaza-7-phosphaadamantane. | Dalton transactions (Cambridge, England : 2003) 20080107 |
| The dipeptidyl peptidase-4 inhibitor vildagliptin improves beta-cell function and insulin sensitivity in subjects with impaired fasting glucose. | Diabetes care 20080101 |
| Characterization of the influence of vildagliptin on model-assessed -cell function in patients with type 2 diabetes and mild hyperglycemia. | The Journal of clinical endocrinology and metabolism 20080101 |
| Effects of the dipeptidyl peptidase-IV inhibitor vildagliptin on incretin hormones, islet function, and postprandial glycemia in subjects with impaired glucose tolerance. | Diabetes care 20080101 |
| Vildagliptin, a novel dipeptidyl peptidase IV inhibitor, has no pharmacokinetic interactions with the antihypertensive agents amlodipine, valsartan, and ramipril in healthy subjects. | Journal of clinical pharmacology 20080101 |
| Efficacy and tolerability of vildagliptin vs. pioglitazone when added to metformin: a 24-week, randomized, double-blind study. | Diabetes, obesity & metabolism 20080101 |
| Update: vildagliptin for the treatment of Type 2 diabetes. | Expert opinion on investigational drugs 20080101 |
| A chiral pool based synthesis of platensimycin. | Angewandte Chemie (International ed. in English) 20080101 |
| Adamantane-resistant influenza infection during the 2004-05 season. | Emerging infectious diseases 20080101 |
| Synthesis of platensimycin. | Angewandte Chemie (International ed. in English) 20080101 |
| Platensimycin: a promising antimicrobial targeting fatty acid synthesis. | Current medicinal chemistry 20080101 |
| [Effects of hemantane on the main subtypes of dopamine receptors in the rat striatum ex vivo]. | Eksperimental'naia i klinicheskaia farmakologiia 20080101 |
| A carbonyl ylide cycloaddition approach to platensimycin. | Angewandte Chemie (International ed. in English) 20080101 |
| [The possibilities of using himantane in the treatment of Parkinson's disease]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101 |
| High-pressure entry into platencin. | Angewandte Chemie (International ed. in English) 20080101 |
| New anti-tuberculosis drugs with novel mechanisms of action. | Current medicinal chemistry 20080101 |
| Substituted 1,3,5-triazaadamantanes: biocompatible and degradable building blocks. | Angewandte Chemie (International ed. in English) 20080101 |
| Beta-cyclodextrin-appended giant amphiphile: aggregation to vesicle polymersomes and immobilisation of enzymes. | Chemistry (Weinheim an der Bergstrasse, Germany) 20080101 |
| [Blockade of the alpha3alpha4 N-cholinoreceptors and GluR1 AMPA receptors eliminates clonic-tonic nicotinic and kainate seizures]. | Eksperimental'naia i klinicheskaia farmakologiia 20080101 |
| [Characteristics of ladasten effect in neurasthenia patients with various EEG parameters]. | Eksperimental'naia i klinicheskaia farmakologiia 20080101 |
| Chemical bonding in the inclusion complex of He in adamantane, He@adam: antithesis and complement. | Chemistry (Weinheim an der Bergstrasse, Germany) 20080101 |
| Vildagliptin: a review of its use in the management of type 2 diabetes mellitus. | Drugs 20080101 |
| Surveillance of adamantane resistance among influenza A H3 viruses isolated in Argentina between 2001 and 2007. | Revista Argentina de microbiologia 20080101 |
| Medicinal chemistry approaches to the inhibition of dipeptidyl peptidase IV. | Current topics in medicinal chemistry 20080101 |
| [Antiviral activity of polycarboxylic substances modified by cage hydrocarbon and sulfoacid pharmacophors against cytomegalovirus infection in vitro]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20080101 |
| Sulphonylureas induced vasorelaxation of mouse arteries. | European journal of pharmacology 20071222 |
| Biosynthetic studies of platensimycin. | Journal of the American Chemical Society 20071219 |
| Total synthesis and antibacterial properties of carbaplatensimycin. | Journal of the American Chemical Society 20071205 |
| [Two breakthroughs in the treatment of type 2 diabetes. Both the receptor agonist and enzyme inhibitors now available in the clinic]. | Lakartidningen 20071205 |
| Soluble epoxide hydrolase: a novel therapeutic target in stroke. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20071201 |
| Incretin receptors for glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide are essential for the sustained metabolic actions of vildagliptin in mice. | Diabetes 20071201 |
| Epoxyeicosatrienoic acids regulate Trp channel dependent Ca2+ signaling and hyperpolarization in endothelial cells. | Arteriosclerosis, thrombosis, and vascular biology 20071201 |
| Management of type 2 diabetes in treatment-naive elderly patients: benefits and risks of vildagliptin monotherapy. | Diabetes care 20071201 |
| Activity of artemether and OZ78 against triclabendazole-resistant Fasciola hepatica. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20071201 |
| Evaluation of the potential for steady-state pharmacokinetic interaction between vildagliptin and simvastatin in healthy subjects. | Current medical research and opinion 20071201 |
| Mapping of cytochrome P450 2B4 substrate binding sites by photolabile probe 3-azidiamantane: identification of putative substrate access regions. | Archives of biochemistry and biophysics 20071201 |
| Pandemic flu vaccine: are we doing enough? | Clinical pharmacology and therapeutics 20071201 |
| Pressure perturbation calorimetry, heat capacity and the role of water in protein stability and interactions. | Biochemical Society transactions 20071201 |
| DPP-4 inhibitors. | Best practice & research. Clinical endocrinology & metabolism 20071201 |
| Clinical management strategies for type 2 diabetes. | JAAPA : official journal of the American Academy of Physician Assistants 20071201 |
| New treatments for type 2 diabetes--the DPP4 inhibitors. | Primary care diabetes 20071201 |
| Discovery of potent and selective adamantane-based small-molecule P2X(7) receptor antagonists/interleukin-1beta inhibitors. | Journal of medicinal chemistry 20071129 |
| 2-phenylimidazopyridines, a new series of Golgi compounds with potent antiviral activity. | Journal of medicinal chemistry 20071129 |
| Evaluation of some adamantane-based synthetic trioxanes against Plasmodium knowlesi in rhesus monkeys. | Life sciences 20071110 |
| An effective enantioselective route to the platensimycin core. | Organic letters 20071108 |
| Iron-mediated degradation kinetics of substituted dispiro-1,2,4-trioxolane antimalarials. | Journal of pharmaceutical sciences 20071101 |
| The dipeptidyl peptidase 4 inhibitor vildagliptin does not accentuate glibenclamide-induced hypoglycemia but reduces glucose-induced glucagon-like peptide 1 and gastric inhibitory polypeptide secretion. | The Journal of clinical endocrinology and metabolism 20071101 |
| Advances in the treatment of tuberculosis. | Clinical pharmacology and therapeutics 20071101 |
| Improved meal-related insulin processing contributes to the enhancement of B-cell function by the DPP-4 inhibitor vildagliptin in patients with type 2 diabetes. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20071101 |
| 1,3-disubstituted ureas functionalized with ether groups are potent inhibitors of the soluble epoxide hydrolase with improved pharmacokinetic properties. | Journal of medicinal chemistry 20071018 |
| DPP-4 inhibition improves glucose tolerance and increases insulin and GLP-1 responses to gastric glucose in association with normalized islet topography in mice with beta-cell-specific overexpression of human islet amyloid polypeptide. | Regulatory peptides 20071004 |
| Precision and sensitivity optimization of quantitative measurements in solid state NMR. | Journal of magnetic resonance (San Diego, Calif. : 1997) 20071001 |
| The effects of ladasten on dopaminergic neurotransmission and hippocampal synaptic plasticity in rats. | Neuropharmacology 20071001 |
| Analysis of vasodilator responses to peroxynitrite in the hindlimb vascular bed of the cat. | Journal of cardiovascular pharmacology 20071001 |
| Clonorchicidal properties of the synthetic trioxolane OZ78. | The Journal of parasitology 20071001 |
| GLP-1-based therapy of type 2 diabetes: GLP-1 mimetics and DPP-IV inhibitors. | Current diabetes reports 20071001 |
| Scanning electron microscopy of nanoscale chemical patterns. | ACS nano 20071001 |
| alpha-selective sialylations at -78 degrees C in nitrile solvents with a 1-adamantanyl thiosialoside. | The Journal of organic chemistry 20070928 |
| Enantioselective synthesis of (-)-platensimycin oxatetracyclic core by using an intramolecular Diels-Alder reaction. | Organic letters 20070927 |
| 1-Adamantanethiolate monolayer displacement kinetics follow a universal form. | Journal of the American Chemical Society 20070905 |
| Comparison between vildagliptin and metformin to sustain reductions in HbA(1c) over 1 year in drug-naïve patients with Type 2 diabetes. | Diabetic medicine : a journal of the British Diabetic Association 20070901 |
| Dose proportionality and the effect of food on vildagliptin, a novel dipeptidyl peptidase IV inhibitor, in healthy volunteers. | Journal of clinical pharmacology 20070901 |
| Antitumor activity of the combination of synthetic retinoid ST1926 and cisplatin in ovarian carcinoma models. | Annals of oncology : official journal of the European Society for Medical Oncology 20070901 |
| The DPP-4 inhibitor vildagliptin: robust glycaemic control in type 2 diabetes and beyond. | Diabetes, obesity & metabolism 20070901 |
| Characterization and alkane oxidation activity of a diastereopure seven-coordinate iron(III) alkylperoxo complex. | Dalton transactions (Cambridge, England : 2003) 20070821 |
| New tuberculosis therapeutics: a growing pipeline. | The Journal of infectious diseases 20070815 |
| Orally bioavailable potent soluble epoxide hydrolase inhibitors. | Journal of medicinal chemistry 20070809 |
| Enantioselective route to platensimycin: an intramolecular Robinson annulation approach. | Journal of the American Chemical Society 20070808 |
| The emergence of adamantane resistance in influenza A(H1) viruses in Australia and regionally in 2006. | Antiviral research 20070801 |
| The genesis and spread of reassortment human influenza A/H3N2 viruses conferring adamantane resistance. | Molecular biology and evolution 20070801 |
| Cholecystokinin CCK2 receptors mediate the peptide's inhibitory actions on the contractile activity of human distal colon via the nitric oxide pathway. | British journal of pharmacology 20070801 |
| Design and synthesis of bioactive adamantane spiro heterocycles. | Bioorganic & medicinal chemistry letters 20070801 |
| Dipeptidyl peptidase 4 inhibition and vildagliptin therapy for type 2 diabetes. | International journal of clinical practice. Supplement 20070801 |
| Dipeptidyl peptidase IV inhibitors and the incretin system in type 2 diabetes mellitus. | Pharmacotherapy 20070801 |
| Evaluation of pharmacokinetic interactions between vildagliptin and digoxin in healthy volunteers. | Journal of clinical pharmacology 20070801 |
| Efficacy and safety of incretin therapy in type 2 diabetes: systematic review and meta-analysis. | JAMA 20070711 |
| Direct stereocontrolled synthesis of 3-amino-3-deoxy-beta-mannopyranosides: importance of the nitrogen protecting group on stereoselectivity. | The Journal of organic chemistry 20070706 |
| Increasing or stabilizing renal epoxyeicosatrienoic acid production attenuates abnormal renal function and hypertension in obese rats. | American journal of physiology. Renal physiology 20070701 |
| Effective switch-on fluorescence sensing of zinc(II) ion by 8-aminoquinolino-beta-cyclodextrin/adamantaneacetic acid system in water. | Bioorganic & medicinal chemistry 20070701 |
| The influence of hepatic impairment on the pharmacokinetics of the dipeptidyl peptidase IV (DPP-4) inhibitor vildagliptin. | European journal of clinical pharmacology 20070701 |
| [New concepts in the treatment of type 2 diabetes]. | Der Internist 20070701 |
| Mining and engineering natural-product biosynthetic pathways. | Nature chemical biology 20070701 |
| Proteomic analysis identifies oxidative stress induction by adaphostin. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070615 |
| Combination of dipeptidylpeptidase IV inhibitor and low dose thiazolidinedione: preclinical efficacy and safety in db/db mice. | Life sciences 20070613 |
| An expedient enantioselective strategy for the oxatetracyclic core of platensimycin. | Organic letters 20070607 |
| Dipeptidyl peptidase-4 inhibitors: clinical data and clinical implications. | Diabetes care 20070601 |
| Inhibition of KATP channels in the rat tail artery by neurally released noradrenaline acting on postjunctional alpha2-adrenoceptors. | The Journal of physiology 20070601 |
| Addition of vildagliptin to insulin improves glycaemic control in type 2 diabetes. | Diabetologia 20070601 |
| Tailored slice selection in solid-state MRI by DANTE under magic-echo line narrowing. | Journal of magnetic resonance (San Diego, Calif. : 1997) 20070601 |
| Which patients are candidates for dipeptidyl peptidase IV inhibitors? | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070601 |
| Vildagliptin: a novel oral therapy for type 2 diabetes mellitus. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070601 |
| An adamantyl-substituted retinoid-derived molecule that inhibits cancer cell growth and angiogenesis by inducing apoptosis and binds to small heterodimer partner nuclear receptor: effects of modifying its carboxylate group on apoptosis, proliferation, and protein-tyrosine phosphatase activity. | Journal of medicinal chemistry 20070531 |
| Gas-phase diastereoselectivity of secondary 5-substituted (X)-adamant-2-yl (X = F, Si(CH(3))(3)) cations. | The Journal of organic chemistry 20070525 |
| New treatments for diabetes. | The New England journal of medicine 20070524 |
| Formal synthesis of (+/-)-platensimycin. | Chemical communications (Cambridge, England) 20070521 |
| Discovery and biological evaluation of adamantyl amide 11beta-HSD1 inhibitors. | Bioorganic & medicinal chemistry letters 20070515 |
| Dipeptidyl peptidase 8/9-like activity in human leukocytes. | Journal of leukocyte biology 20070501 |
| Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity. | Diabetes 20070501 |
| Vitamin D3 derivatives with adamantane or lactone ring side chains are cell type-selective vitamin D receptor modulators. | Molecular pharmacology 20070501 |
| Sinaicinone, a complex adamantanyl derivative from Hypericum sinaicum. | Phytochemistry 20070501 |
| Pharmacodynamics of vildagliptin in patients with type 2 diabetes during OGTT. | Journal of clinical pharmacology 20070501 |
| The role of vildagliptin in the management of type 2 diabetes mellitus. | The Annals of pharmacotherapy 20070501 |
| Pathologically-activated therapeutics for neuroprotection: mechanism of NMDA receptor block by memantine and S-nitrosylation. | Current drug targets 20070501 |
| Effect of the novel oral dipeptidyl peptidase IV inhibitor vildagliptin on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects. | Current medical research and opinion 20070501 |
| Heterogeneity of thylakoid membranes studied by EPR spin probe. | Biochemistry. Biokhimiia 20070501 |
| Formal synthesis of (+/-)-platensimycin. | Organic letters 20070426 |
| Identification of a highly potent vitamin D receptor antagonist: (25S)-26-adamantyl-25-hydroxy-2-methylene-22,23-didehydro-19,27-dinor-20-epi-vitamin D3 (ADMI3). | Archives of biochemistry and biophysics 20070415 |
| Novel amidino-substituted benzimidazoles: synthesis of compounds and inhibition of dipeptidyl peptidase III. | Bioorganic chemistry 20070401 |
| Efficacy and tolerability of vildagliptin monotherapy in drug-naïve patients with type 2 diabetes. | Diabetes research and clinical practice 20070401 |
| Drug therapy of experimental tuberculosis (TB): improved outcome by combining SQ109, a new diamine antibiotic, with existing TB drugs. | Antimicrobial agents and chemotherapy 20070401 |
| The dipeptidyl peptidase IV inhibitor vildagliptin suppresses endogenous glucose production and enhances islet function after single-dose administration in type 2 diabetic patients. | The Journal of clinical endocrinology and metabolism 20070401 |
| Effects of vildagliptin on glucose control over 24 weeks in patients with type 2 diabetes inadequately controlled with metformin. | Diabetes care 20070401 |
| [Incretin enhancers, incretin mimetics: from therapeutic concept to clinical application]. | Orvosi hetilap 20070401 |
| Antiviral therapy and prophylaxis for influenza in children. | Pediatrics 20070401 |
| Inhibition of DPP-4: a new therapeutic approach for the treatment of type 2 diabetes. | Current medical research and opinion 20070401 |
| [Glucagon-like peptide-1 (GLP-1), new target for the treatment of type 2 diabetes]. | Revue medicale de Liege 20070401 |
| Inhibition of mitochondrial respiration as a source of adaphostin-induced reactive oxygen species and cytotoxicity. | The Journal of biological chemistry 20070323 |
| Amperometric biosensor for xanthine with supramolecular architecture. | Chemical communications (Cambridge, England) 20070307 |
| Adaphostin cytoxicity in glioblastoma cells is ROS-dependent and is accompanied by upregulation of heme oxygenase-1. | Cancer chemotherapy and pharmacology 20070301 |
| The novel atypical retinoid ST1926 is active in ATRA resistant neuroblastoma cells acting by a different mechanism. | Biochemical pharmacology 20070301 |
| 3-[2-((2S)-2-cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-3-methyl-butyramide analogues as selective DPP-IV inhibitors for the treatment of type-II diabetes. | Bioorganic & medicinal chemistry letters 20070301 |
| Different target range and cytotoxic specificity of adaphostin and 17-allylamino-17-demethoxygeldanamycin in imatinib-resistant and sensitive cell lines. | Leukemia 20070301 |
| Vildagliptin in combination with pioglitazone improves glycaemic control in patients with type 2 diabetes failing thiazolidinedione monotherapy: a randomized, placebo-controlled study. | Diabetes, obesity & metabolism 20070301 |
| Efficacy and tolerability of initial combination therapy with vildagliptin and pioglitazone compared with component monotherapy in patients with type 2 diabetes. | Diabetes, obesity & metabolism 20070301 |
| Vildagliptin in drug-naïve patients with type 2 diabetes: a 24-week, double-blind, randomized, placebo-controlled, multiple-dose study. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20070301 |
| CCK2 receptors mediate inhibitory effects of cholecystokinin on the motor activity of guinea-pig distal colon. | European journal of pharmacology 20070227 |
| Up-regulation of c-Jun inhibits proliferation and induces apoptosis via caspase-triggered c-Abl cleavage in human multiple myeloma. | Cancer research 20070215 |
| New adamantane-based spiro 1,2,4-trioxanes orally effective against rodent and simian malaria. | Journal of medicinal chemistry 20070208 |
| Increased adamantane resistance in influenza A(H3) viruses in Australia and neighbouring countries in 2005. | Antiviral research 20070201 |
| Functional selectivity of dopamine D1 receptor agonists in regulating the fate of internalized receptors. | Neuropharmacology 20070201 |
| Discovery of adamantane ethers as inhibitors of 11beta-HSD-1: Synthesis and biological evaluation. | Bioorganic & medicinal chemistry letters 20070201 |
| Synthesis, antimicrobial, and anti-inflammatory activities of novel 2-(1-adamantyl)-5-substituted-1,3,4-oxadiazoles and 2-(1-adamantylamino)-5-substituted-1,3,4-thiadiazoles. | European journal of medicinal chemistry 20070201 |
| Comparison of vildagliptin and rosiglitazone monotherapy in patients with type 2 diabetes: a 24-week, double-blind, randomized trial. | Diabetes care 20070201 |
| Gliptins. | Lancet (London, England) 20070127 |
| The reversible binding of anti-human serum albumin to poly beta-cyclodextrin-coated porous silica supports. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070115 |
| Adamantane sulfone and sulfonamide 11-beta-HSD1 Inhibitors. | Bioorganic & medicinal chemistry letters 20070115 |
| Synthesis, anti-tuberculosis activity, and 3D-QSAR study of 4-(adamantan-1-yl)-2-substituted quinolines. | Bioorganic & medicinal chemistry 20070115 |
| Isofagomine- and 2,5-anhydro-2,5-imino-D-glucitol-based glucocerebrosidase pharmacological chaperones for Gaucher disease intervention. | Journal of medicinal chemistry 20070111 |
| Discovery and metabolic stabilization of potent and selective 2-amino-N-(adamant-2-yl) acetamide 11beta-hydroxysteroid dehydrogenase type 1 inhibitors. | Journal of medicinal chemistry 20070111 |
| Supramolecular control of unwinding and rewinding of a double helix of oligoresorcinol using cyclodextrin/adamantane system. | Journal of the American Chemical Society 20070110 |
| Selective blockade of Ca2+ permeable AMPA receptors in CA1 area of rat hippocampus. | Neuroscience 20070105 |
| Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase. | Bioorganic & medicinal chemistry 20070101 |
| Liraglutide, a long-acting glucagon-like peptide-1 analog, reduces body weight and food intake in obese candy-fed rats, whereas a dipeptidyl peptidase-IV inhibitor, vildagliptin, does not. | Diabetes 20070101 |
| Vildagliptin does not affect C-peptide clearance in patients with type 2 diabetes. | Journal of clinical pharmacology 20070101 |
| Adamantyl-substituted retinoid-related molecules bind small heterodimer partner and modulate the Sin3A repressor. | Cancer research 20070101 |
| Physicochemical and biological characterization of targeted, nucleic acid-containing nanoparticles. | Bioconjugate chemistry 20070101 |
| Cyclodextrin complexes of polymers bearing adamantyl groups: host-guest interactions and the effect of spacers on water solubility. | Angewandte Chemie (International ed. in English) 20070101 |
| Chemiluminescent determination of leukocyte alkaline phosphatase: an advantageous alternative to the cytochemical assay. | Journal of clinical laboratory analysis 20070101 |
| Asymmetric total syntheses of platensimycin. | Angewandte Chemie (International ed. in English) 20070101 |
| Adamantaplatensimycin: a bioactive analogue of platensimycin. | Angewandte Chemie (International ed. in English) 20070101 |
| Pharmacokinetics and pharmacodynamics of vildagliptin in patients with type 2 diabetes mellitus. | Clinical pharmacokinetics 20070101 |
| A hydrophilic cyclodextrin duplex forming supramolecular assemblies by physical cross-linking of a biopolymer. | Chemistry (Weinheim an der Bergstrasse, Germany) 20070101 |
| The absolute oral bioavailability and population-based pharmacokinetic modelling of a novel dipeptidylpeptidase-IV inhibitor, vildagliptin, in healthy volunteers. | Clinical pharmacokinetics 20070101 |
| Protecting-group-free formal synthesis of platensimycin. | Angewandte Chemie (International ed. in English) 20070101 |
| [The acute and subchronic effects of hemantane on [3H]-dopamine reuptake in rat striatal synaptosomes ex vivo]. | Eksperimental'naia i klinicheskaia farmakologiia 20070101 |
| [Antimicrobial effect of 4-(adamantyl-1)-1-(1-aminobutyl)benzol]. | Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) 20070101 |
| Synthesis of 1-{4-[4-(adamant-1-yl)phenoxymethyl]-2-(4-bromophenyl)- 1,3-dioxolan-2-ylmethyl}imidazole with expected antifungal and antibacterial activity. | Acta poloniae pharmaceutica 20070101 |
| [Carboxy mimetic derivatives of nucleic acid polymeric backbones inhibiting human cytomegalovirus. 1. In vitro microbicidal effect]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20070101 |
| Small organic compounds enhance antigen loading of class II major histocompatibility complex proteins by targeting the polymorphic P1 pocket. | The Journal of biological chemistry 20061215 |
| Molecular mechanism of adaphostin-mediated G1 arrest in prostate cancer (PC-3) cells: signaling events mediated by hepatocyte growth factor receptor, c-Met, and p38 MAPK pathways. | The Journal of biological chemistry 20061208 |
| In vitro biological efficiency of tenocyclidine-TCP and its adamantane derivative TAMORF. | Toxicology in vitro : an international journal published in association with BIBRA 20061201 |
| 7-But-2-ynyl-9-(6-methoxy-pyridin-3-yl)-6-piperazin-1-yl-7,9-dihydro-purin-8-one is a novel competitive and selective inhibitor of dipeptidyl peptidase IV with an antihyperglycemic activity. | The Journal of pharmacology and experimental therapeutics 20061201 |
| Adamantane 11-beta-HSD-1 inhibitors: Application of an isocyanide multicomponent reaction. | Bioorganic & medicinal chemistry letters 20061201 |
| The synthetic peroxide OZ78 is effective against Echinostoma caproni and Fasciola hepatica. | The Journal of antimicrobial chemotherapy 20061201 |
| Dipeptidyl peptidase IV (DPP IV) inhibitors: A newly emerging drug class for the treatment of type 2 diabetes. | Diabetes & vascular disease research 20061201 |
| The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes. | Lancet (London, England) 20061111 |
| A nonfeminizing estrogen analog protects against ethanol withdrawal toxicity in immortalized hippocampal cells. | The Journal of pharmacology and experimental therapeutics 20061101 |
| Molecular aspects of antitumor effects of a new platinum(IV) drug. | Molecular pharmacology 20061101 |
| DPP-4 inhibitors and their potential role in the management of type 2 diabetes. | International journal of clinical practice 20061101 |
| How do different GLP-1 mimetics differ in their actions? | Current diabetes reports 20061101 |
| Exenatide: a novel approach for treatment of type 2 diabetes. | Southern medical journal 20061101 |
| Total synthesis of platensimycin. | Angewandte Chemie (International ed. in English) 20061027 |
| Dirhodium tetracarboxylates derived from adamantylglycine as chiral catalysts for enantioselective C-h aminations. | Organic letters 20061026 |
| Metabolic mimics: thiol responsive drug release. | Journal of colloid and interface science 20061015 |
| Synthesis and structural activity relationship of 11beta-HSD1 inhibitors with novel adamantane replacements. | Bioorganic & medicinal chemistry letters 20061015 |
| Synthesis and biological evaluation of heterocycle containing adamantane 11beta-HSD1 inhibitors. | Bioorganic & medicinal chemistry letters 20061015 |
| Shift shown in influenza A adamantane resistance. | JAMA 20061004 |
| Shift shown in influenza A adamantane resistance. | JAMA 20061004 |
| Adaphostin and bortezomib induce oxidative injury and apoptosis in imatinib mesylate-resistant hematopoietic cells expressing mutant forms of Bcr/Abl. | Leukemia research 20061001 |
| Synthesis, conformational characteristics and anti-influenza virus A activity of some 2-adamantylsubstituted azacycles. | Bioorganic chemistry 20061001 |
| Resistance to anti-influenza drugs: adamantanes and neuraminidase inhibitors. | Expert review of anti-infective therapy 20061001 |
| C-glycoside clustering on calix[4]arene, adamantane, and benzene scaffolds through 1,2,3-triazole linkers. | The Journal of organic chemistry 20060929 |
| Oxaza adamantyl cannabinoids. A new class of cannabinoid receptor probes. | The Journal of organic chemistry 20060929 |
| Supramolecular assembly of cyclodextrin-based nanoparticles on solid surfaces for gene delivery. | Langmuir : the ACS journal of surfaces and colloids 20060926 |
| Effect of dopamine D1 receptor antagonist SCH23390 and D1 agonist A77636 on active allothetic place avoidance, a spatial cognition task. | Behavioural brain research 20060925 |
| Supramolecular complexes of spin-labelled cyclodextrins. | Organic & biomolecular chemistry 20060921 |
| Forensic fingerprinting of diamondoids for correlation and differentiation of spilled oil and petroleum products. | Environmental science & technology 20060915 |
| Isolation, structure, and absolute stereochemistry of platensimycin, a broad spectrum antibiotic discovered using an antisense differential sensitivity strategy. | Journal of the American Chemical Society 20060913 |
| Substituted adamantyl-urea inhibitors of the soluble epoxide hydrolase dilate mesenteric resistance vessels. | The Journal of pharmacology and experimental therapeutics 20060901 |
| Antitumor activity of the retinoid-related molecules (E)-3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid (ST1926) and 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) in F9 teratocarcinoma: Role of retinoic acid receptor gamma and retinoid-independent pathways. | Molecular pharmacology 20060901 |
| Vildagliptin therapy reduces postprandial intestinal triglyceride-rich lipoprotein particles in patients with type 2 diabetes. | Diabetologia 20060901 |
| Adaphostin has significant and selective activity against chronic and acute myeloid leukemia cells. | Cancer science 20060901 |
| [Development of environmentally benign oxidations using hypervalent iodine (III) reagents]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20060901 |
| Platensimycin, a new antibiotic and 'superbug challenger' from nature. | ChemMedChem 20060901 |
| Oral agents for type 2 diabetes reduce HbA1c, are weight neutral. | Geriatrics 20060901 |
| Material surfaces and MRSA. | Medical device technology 20060901 |
| Dirhodium tetracarboxylate derived from adamantylglycine as a chiral catalyst for carbenoid reactions. | Organic letters 20060803 |
| Synergistic interactions of SQ109, a new ethylene diamine, with front-line antitubercular drugs in vitro. | The Journal of antimicrobial chemotherapy 20060801 |
| American Diabetes Association--66th scientific sessions. 9-13 June 2006, Washington, DC, USA. | IDrugs : the investigational drugs journal 20060801 |
| Improving potency, selectivity, and water solubility of adenosine A1 receptor antagonists: xanthines modified at position 3 and related pyrimido[1,2,3-cd]purinediones. | ChemMedChem 20060801 |
| Vildagliptin: a novel DPP-4 inhibitor with pancreatic islet enhancement activity for treatment of patients with type 2 diabetes. | Drugs of today (Barcelona, Spain : 1998) 20060801 |
| Directed assembly and separation of self-assembled monolayers via electrochemical processing. | The journal of physical chemistry. B 20060727 |
| Reaction of thioketones with propiolic acids. | Organic & biomolecular chemistry 20060721 |
| New lamellar structure formed by an adamantyl derivative of cholic acid. | The journal of physical chemistry. B 20060720 |
| Computational studies of ethynyl- and diethynyl-expanded tetrahedranes, prismanes, cubanes, and adamantanes. | The Journal of organic chemistry 20060707 |
| 2-azaadamantane N-oxyl (AZADO) and 1-Me-AZADO: highly efficient organocatalysts for oxidation of alcohols. | Journal of the American Chemical Society 20060705 |
| Regioselective hydroxylation of adamantane by Streptomyces griseoplanus cells. | Applied microbiology and biotechnology 20060701 |
| The first intermediates in the bromination of bicyclo[3.3.1]nonylidenebicyclo[3.3.1]nonane, combination of experiments and theoretical results. | Journal of molecular modeling 20060701 |
| Irt>t schedule controlled behavior in 'learned-helpless' rats: effects from a cannabinoid agonist. | Neuropharmacology 20060701 |
| The pharmacology of aminoadamantane nitrates. | Current Alzheimer research 20060701 |
| [Cytosine demethylation in the tyrosine hydroxylase gene promoter in the hypothalamus cells of the rat brain under the action of an aminoadamantane derivative Ladasten]. | Genetika 20060701 |
| Fast catalytic hydroxylation of hydrocarbons with ruthenium porphyrins. | Inorganic chemistry 20060612 |
| Single molecular anatomy of solvophobic effects in host-guest interactions based on surface tension using atomic force microscopy. | Physical review letters 20060609 |
| Raman spectroscopy of diamondoids. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060601 |
| Tumor-cell-targeted methionine-enkephalin analogues containing unnatural amino acids: design, synthesis, and in vitro antitumor activity. | Journal of medicinal chemistry 20060601 |
| [Adamantane resistance among influenza A (H3N2) viruses isolated from the mainland of China]. | Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 20060601 |
| Twelve-week monotherapy with the DPP-4 inhibitor vildagliptin improves glycemic control in subjects with type 2 diabetes. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20060601 |
| Effects of a neurotensin analogue (PD149163) and antagonist (SR142948A) on the scopolamine-induced deficits in a novel object discrimination task. | Behavioural pharmacology 20060601 |
| Regulation of Nur77 nuclear export by c-Jun N-terminal kinase and Akt. | Oncogene 20060518 |
| Antibiotic faces uncertain future. | Nature 20060518 |
| Microbiology: antibiotic stops 'ping-pong' match. | Nature 20060518 |
| Platensimycin is a selective FabF inhibitor with potent antibiotic properties. | Nature 20060518 |
| An EPR study of the C-O bond activation of 1,2-epoxybutane by ground-state Al atoms. | The journal of physical chemistry. A 20060504 |
| Preclinical pharmacology of the novel antitumor agent adaphostin, a tyrphostin analog that inhibits bcr/abl. | Cancer chemotherapy and pharmacology 20060501 |
| Induction of GDF-15/NAG-1/MIC-1 in human lung carcinoma cells by retinoid-related molecules and assessment of its role in apoptosis. | Cancer biology & therapy 20060501 |
| Small organic molecules that modulate gene transcription. | Drug discovery today 20060501 |
| Molecule of the month. Vildagilptin. | Drug news & perspectives 20060501 |
| Functionalized nanodiamonds part 3: thiolation of tertiary/bridgehead alcohols. | Organic letters 20060427 |
| A novel adamantane derivative attenuates retinal ischemia-reperfusion damage in the rat retina through sigma1 receptors. | European journal of pharmacology 20060424 |
| A unidirectional energy transfer cascade process in a ruthenium junction self-assembled by alpha- and beta-cyclodextrins. | Journal of the American Chemical Society 20060412 |
| Immunosensors for pollutants working in organic media. Study of performances of different tracers with luminescent detection. | Analytical and bioanalytical chemistry 20060401 |
| Diabetes: assessing the pipeline. | Atherosclerosis. Supplements 20060401 |
| The antitumor effect of a novel differentiation inducer, 2, 2-Bis (4-(4-amino-3-hydroxyphenoxy) phenyl) adamantane (DPA), in combinatory therapy on human colon cancer. | International journal of oncology 20060401 |
| Vildagliptin: an inhibitor of dipeptidyl peptidase-4 with antidiabetic properties. | Expert opinion on investigational drugs 20060401 |
| Electron paramagnetic resonance study of the mononuclear Al species formed in the reaction of Al atoms and cyclopropylamine at 77 k in an adamantane matrix. | The journal of physical chemistry. A 20060323 |
| Influenza-associated deaths among children. | The New England journal of medicine 20060323 |
| Bradykinin B2 receptors mediate pulmonary sympathetic afferents induced reflexes in rabbits. | Life sciences 20060320 |
| Adaphostin-induced oxidative stress overcomes BCR/ABL mutation-dependent and -independent imatinib resistance. | Blood 20060315 |
| Functional in vitro characterization of CR 3394: a novel voltage dependent N-methyl-D-aspartate (NMDA) receptor antagonist. | Neuropharmacology 20060301 |
| Interspecies pharmacokinetics and in vitro metabolism of SQ109. | British journal of pharmacology 20060301 |
| Controlled synthesis and inclusion ability of a hyaluronic acid derivative bearing beta-cyclodextrin molecules. | Biomacromolecules 20060301 |
| [Dipeptidylpeptidase IV inhibitors and dual action PPAR-agonists]. | Medizinische Monatsschrift fur Pharmazeuten 20060301 |
| Drug resistance among influenza A viruses isolated in Italy from 2000 to 2005: are the emergence of Adamantane-resistant viruses cause of concern? | Journal of preventive medicine and hygiene 20060301 |
| The anorectic effect of the selective dopamine D1-receptor agonist A-77636 determined by meal pattern analysis in free-feeding rats. | European journal of pharmacology 20060227 |
| Adamantane resistance among influenza A viruses isolated early during the 2005-2006 influenza season in the United States. | JAMA 20060222 |
| Adamantane resistance in influenza A. | JAMA 20060222 |
| A novel soluble mimic of the glycolipid, globotriaosyl ceramide inhibits HIV infection. | AIDS (London, England) 20060214 |
| Biocatalytic ammonolysis of (5S)-4,5-dihydro-1H-pyrrole-1,5-dicarboxylic acid, 1-(1,1-dimethylethyl)-5-ethyl ester: preparation of an intermediate to the dipeptidyl peptidase IV inhibitor Saxagliptin. | Bioorganic & medicinal chemistry letters 20060201 |
| High levels of adamantane resistance among influenza A (H3N2) viruses and interim guidelines for use of antiviral agents--United States, 2005-06 influenza season. | MMWR. Morbidity and mortality weekly report 20060120 |
| Peptidic delta opioid receptor agonists produce antidepressant-like effects in the forced swim test and regulate BDNF mRNA expression in rats. | Brain research 20060119 |
| RF9, a potent and selective neuropeptide FF receptor antagonist, prevents opioid-induced tolerance associated with hyperalgesia. | Proceedings of the National Academy of Sciences of the United States of America 20060110 |
| Adaphostin and other anticancer drugs quench the fluorescence of mitochondrial potential probes. | Cell death and differentiation 20060101 |
| The tyrphostin adaphostin interacts synergistically with proteasome inhibitors to induce apoptosis in human leukemia cells through a reactive oxygen species (ROS)-dependent mechanism. | Blood 20060101 |
| Evaluation of antidotal effects of adamantyl derivative Tamorf in soman poisoning. | Journal of applied toxicology : JAT 20060101 |
| Dipeptidyl-peptidase IV converts intact B-type natriuretic peptide into its des-SerPro form. | Clinical chemistry 20060101 |
| The binding interaction of synthetic ozonide antimalarials with natural and modified beta-cyclodextrins. | Journal of pharmaceutical sciences 20060101 |
| Mechanism of Gly-Pro-pNA cleavage catalyzed by dipeptidyl peptidase-IV and its inhibition by saxagliptin (BMS-477118). | Archives of biochemistry and biophysics 20060101 |
| [Thermoprotector properties of a combination of sydnocarb with ladasten]. | Eksperimental'naia i klinicheskaia farmakologiia 20060101 |
| TNF-alpha production-enhancing activity of 2-(1-adamantylamino)-6-methylpyridine (AdAMP) in cultures of human normal and neoplastic cells. | Anticancer research 20060101 |
| Therapeutic options in development for management of diabetes: pharmacologic agents and new technologies. | Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20060101 |
| [RF9, a powerful and selective antagonist of the neuropeptide FF receptors, prevents the development of the tolerance to opioids]. | Medecine sciences : M/S 20060101 |
| [Comparative study of the effect of Ladasten, Sydnocarb and their combination on physical work ability of laboratory animals]. | Eksperimental'naia i klinicheskaia farmakologiia 20060101 |
| Pharmacological Profile of U-37883A, a Channel Blocker of Smooth Muscle-Type ATP-Sensitive K Channels. | Cardiovascular drug reviews 20060101 |
| [Pilot clinical trial of ladasten]. | Eksperimental'naia i klinicheskaia farmakologiia 20060101 |
| [An old pathway to new antibiotics--platensimycin]. | Pharmazie in unserer Zeit 20060101 |
| Soluble adamantyl glycosphingolipid analogs as probes of glycosphingolipid function. | Methods in molecular biology (Clifton, N.J.) 20060101 |
| Novel method to identify illegal diesel fuel, I: use of adamantane or [1, 2-D2] n-tetradecane as chemical marker. | Environmental sciences : an international journal of environmental physiology and toxicology 20060101 |
| Vildagliptin. | Drugs 20060101 |
| Synthesis and antibacterial activity of 5-adamantan-1-yl-methyl analogues of trimethoprim. | Acta poloniae pharmaceutica 20060101 |
| [Therapeutic efficacy of 4-(adamantyl-1)-1-(1-aminobutyl) benzene in experimental fungal pathology]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20060101 |
| New bradykinin analogues modified in the C-terminal part with sterically restricted 1-aminocyclohexane-1-carboxylic acid. | Journal of medicinal chemistry 20051215 |
| Evidence for different types of water participation in the solvolysis of 1-adamantyl, tert-butyl, and methyl chlorides from density functional theory computations. | The Journal of organic chemistry 20051209 |
| Skeleton-selective fluorescent chemosensor based on cyclodextrin bearing a 4-amino-7-nitrobenz-2-oxa-1,3-diazole moiety. | Organic & biomolecular chemistry 20051207 |
| BP-1107 [{2-[4-(2,4-dioxo-thiazolidin-5-ylmethyl)-phenoxy]-ethyl}-methyl-amide]: a novel synthetic thiazolidinedione that inhibits epidermal hyperplasia in psoriatic skin-severe-combined immunodeficient mouse transplants after topical application. | The Journal of pharmacology and experimental therapeutics 20051201 |
| An epoxide hydrolase inhibitor, 12-(3-adamantan-1-yl-ureido)dodecanoic acid (AUDA), reduces ischemic cerebral infarct size in stroke-prone spontaneously hypertensive rats. | Journal of cardiovascular pharmacology 20051201 |
| Small molecules thwart crash and burn. | Nature chemical biology 20051201 |
| Small molecules that delay S phase suppress a zebrafish bmyb mutant. | Nature chemical biology 20051201 |
| Functionalized nanodiamonds part I. An experimental assessment of diamantane and computational predictions for higher diamondoids. | Chemistry (Weinheim an der Bergstrasse, Germany) 20051118 |
| Multiple actions of U-37883A, an ATP-sensitive K+ channel blocker, on membrane currents in pig urethra. | European journal of pharmacology 20051107 |
| Acute and chronic effects of the incretin enhancer vildagliptin in insulin-resistant rats. | The Journal of pharmacology and experimental therapeutics 20051101 |
| Pharmacoproteomic effects of isoniazid, ethambutol, and N-geranyl-N'-(2-adamantyl)ethane-1,2-diamine (SQ109) on Mycobacterium tuberculosis H37Rv. | The Journal of pharmacology and experimental therapeutics 20051101 |
| Improved glycaemic control with dipeptidyl peptidase-4 inhibition in patients with type 2 diabetes: vildagliptin (LAF237) dose response. | Diabetes, obesity & metabolism 20051101 |
| Effective inhibition of experimental metastasis and prolongation of survival in mice by a potent factor Xa-specific synthetic serine protease inhibitor with weak anticoagulant activity. | Thrombosis and haemostasis 20051101 |
| The role of Mcl-1 downregulation in the proapoptotic activity of the multikinase inhibitor BAY 43-9006. | Oncogene 20051020 |
| Beta-cell expression of a dominant-negative HNF-1alpha compromises the ability of inhibition of dipeptidyl peptidase-4 to elicit a long-term augmentation of insulin secretion in mice. | European journal of pharmacology 20051003 |
| Rendering of quantum topological atoms and bonds. | Journal of molecular graphics & modelling 20051001 |
| Adamantyl triazoles as selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1. | Bioorganic & medicinal chemistry letters 20051001 |
| An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-sensitive hypertension. | Hypertension (Dallas, Tex. : 1979) 20051001 |
| Resistance to anti-influenza agents. | Lancet (London, England) 20051001 |
| Incidence of adamantane resistance among influenza A (H3N2) viruses isolated worldwide from 1994 to 2005: a cause for concern. | Lancet (London, England) 20051001 |
| Incretins: what does the future hold? | Diabetes technology & therapeutics 20051001 |
| Neuraminidase inhibitors for influenza. | The New England journal of medicine 20050929 |
| Boc-protected amines via a mild and efficient one-pot Curtius rearrangement. | Organic letters 20050915 |
| Incretin mimetics: promising new therapeutic options in the treatment of type 2 diabetes. | Journal of managed care pharmacy : JMCP 20050901 |
| Transcriptional profiling identifies altered intracellular labile iron homeostasis as a contributing factor to the toxicity of adaphostin: decreased vascular endothelial growth factor secretion is independent of hypoxia-inducible factor-1 regulation. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050901 |
| The novel cannabinoid agonist AM 411 produces a biphasic effect on accuracy in a visual target detection task in rats. | Behavioural pharmacology 20050901 |
| [Small molecules that control gene expression]. | Seikagaku. The Journal of Japanese Biochemical Society 20050901 |
| Vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed beta-cell function in patients with type 2 diabetes. | The Journal of clinical endocrinology and metabolism 20050801 |
| Artificial transcriptional activation domains. | Chembiochem : a European journal of chemical biology 20050801 |
| Design of antagonists for NMDA and AMPA receptors. | Neuropharmacology 20050801 |
| Peak shape modeling by Haarhoff-Van der Linde function for the determination of correct migration times: a new insight into affinity capillary electrophoresis. | Electrophoresis 20050801 |
| Improved meal-related beta-cell function and insulin sensitivity by the dipeptidyl peptidase-IV inhibitor vildagliptin in metformin-treated patients with type 2 diabetes over 1 year. | Diabetes care 20050801 |
| American Diabetes Association - 65th Scientific Sessions. DDP-IV inhibitors. | IDrugs : the investigational drugs journal 20050801 |
| Synthesis and structure-activity relationships of a new series of retinoid-related biphenyl-4-ylacrylic acids endowed with antiproliferative and proapoptotic activity. | Journal of medicinal chemistry 20050728 |
| Spiro and dispiro-1,2,4-trioxolanes as antimalarial peroxides: charting a workable structure-activity relationship using simple prototypes. | Journal of medicinal chemistry 20050728 |
| Discovery and preclinical profile of Saxagliptin (BMS-477118): a highly potent, long-acting, orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. | Journal of medicinal chemistry 20050728 |
| Adamantyl cannabinoids: a novel class of cannabinergic ligands. | Journal of medicinal chemistry 20050714 |
| Tuning tetranuclear manganese-oxo core electronic properties: adamantane-shaped complexes synthesized by ligand exchange. | Inorganic chemistry 20050711 |
| Two mechanisms of action of the adamantane derivative IEM-1460 at human AMPA-type glutamate receptors. | British journal of pharmacology 20050701 |
| Inhibition of dipeptidyl-peptidase IV catalyzed peptide truncation by Vildagliptin ((2S)-{[(3-hydroxyadamantan-1-yl)amino]acetyl}-pyrrolidine-2-carbonitrile). | Biochemical pharmacology 20050701 |
| Development of resistance to the atypical retinoid, ST1926, in the lung carcinoma cell line H460 is associated with reduced formation of DNA strand breaks and a defective DNA damage response. | Neoplasia (New York, N.Y.) 20050701 |
| Dispiro-1,2,4-trioxane analogues of a prototype dispiro-1,2,4-trioxolane: mechanistic comparators for artemisinin in the context of reaction pathways with iron(II). | The Journal of organic chemistry 20050624 |
| Potent estrogen receptor ligands based on bisphenols with a globular hydrophobic core. | Journal of medicinal chemistry 20050616 |
| In vitro and in vivo evaluation of ruthenium(II)-arene PTA complexes. | Journal of medicinal chemistry 20050616 |
| Adamantoylated monosaccharides: new compounds for modification of the properties of cyclodextrin-containing materials. | Carbohydrate research 20050613 |
| 1H NMR studies on the hydrogen-bonding network in mono-altro-beta-cyclodextrin and its complex with adamantane-1-carboxylic acid. | Carbohydrate research 20050613 |
| Apoptosis induction by a novel retinoid-related molecule requires nuclear factor-kappaB activation. | Cancer research 20050601 |
| Neurobiology of executive functions: catecholamine influences on prefrontal cortical functions. | Biological psychiatry 20050601 |
| Optimization of amide-based inhibitors of soluble epoxide hydrolase with improved water solubility. | Journal of medicinal chemistry 20050519 |
| Complexation of adamantyl compounds by beta-cyclodextrin and monoaminoderivatives. | The journal of physical chemistry. B 20050519 |
| Interaction of acetylcholine with Kir6.1 channels heterologously expressed in human embryonic kidney cells. | European journal of pharmacology 20050516 |
| Effects of rotational symmetry order on the solid state dynamics of phenylene and diamantane rotators. | Journal of the American Chemical Society 20050511 |
| 2:2 Fe(III):ligand and 'adamantane core' 4:2 Fe(III):ligand (hydr)oxo complexes of an acyclic ditopic ligand. | Dalton transactions (Cambridge, England : 2003) 20050505 |
| Endogenous neurotensin in the ventral tegmental area contributes to amphetamine behavioral sensitization. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050501 |
| Raman study of structural relaxation and boson peak in amorphous films of adamantane. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050501 |
| Treatments and devices for future diabetes management. | Nursing times 20050501 |
| Behavioral effects of the novel cannabinoid full agonist AM 411. | Pharmacology, biochemistry, and behavior 20050501 |
| Short-term effects of endocrine-disrupting chemicals on the expression of estrogen-responsive genes in male medaka (Oryzias latipes). | Aquatic toxicology (Amsterdam, Netherlands) 20050430 |
| The novel GABA adamantane derivative (AdGABA): design, synthesis, and activity relationship with gabapentin. | Bioorganic & medicinal chemistry 20050415 |
| Luminescent ruthenium(II)- and rhenium(I)-diimine wires bind nitric oxide synthase. | Journal of the American Chemical Society 20050413 |
| Soluble epoxide hydrolase is a main effector of angiotensin II-induced hypertension. | Hypertension (Dallas, Tex. : 1979) 20050401 |
| Synthesis and water solubility of adamantyl-OEG-fullerene hybrids. | The Journal of organic chemistry 20050401 |
| Triflic acid-catalyzed adamantylation of aromatics in [BMIM][OTf] ionic liquid; synthetic scope and mechanistic insight. | Organic & biomolecular chemistry 20050321 |
| Modulation of survival signaling pathways and persistence of the genotoxic stress as a basis for the synergistic interaction between the atypical retinoid ST1926 and the epidermal growth factor receptor inhibitor ZD1839. | Cancer research 20050315 |
| Adaphostin-induced apoptosis in CLL B cells is associated with induction of oxidative stress and exhibits synergy with fludarabine. | Blood 20050301 |
| The adamantane-derived bananins are potent inhibitors of the helicase activities and replication of SARS coronavirus. | Chemistry & biology 20050301 |
| Psychotropic effects of sidnocarb and ladasten in inbred mice with different reaction to emotional stress. | Bulletin of experimental biology and medicine 20050301 |
| Solutes probe hydration in specific association of cyclodextrin and adamantane. | Journal of the American Chemical Society 20050223 |
| Synthesis, X-ray crystal structure study, and cytostatic and antiviral evaluation of the novel cycloalkyl-N-aryl-hydroxamic acids. | Journal of medicinal chemistry 20050210 |
| Substrate modulation of the properties and reactivity of the oxy-ferrous and hydroperoxo-ferric intermediates of cytochrome P450cam as shown by cryoreduction-EPR/ENDOR spectroscopy. | Journal of the American Chemical Society 20050209 |
| Vibrational spectra and chemical quantum calculations for 2-adamantylamino-5-nitropyridine crystals--a novel material for laser Raman converters. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050201 |
| Novel spiroanellated 1,2,4-trioxanes with high in vitro antimalarial activities. | Bioorganic & medicinal chemistry letters 20050201 |
| Structural requirements for inhibitors of cytochromes P450 2B: assessment of the enzyme interaction with diamondoids. | Journal of enzyme inhibition and medicinal chemistry 20050201 |
| Effects of 1, 6-Bis[4-(4-amino-3-hydroxyphenoxy)phenyl]diamantane (DPD), a reactive oxygen species and apoptosis inducing agent, on human leukemia cells in vitro and in vivo. | Toxicology and applied pharmacology 20050101 |
| Antitumor effect of valorphin in vitro and in vivo: combined action with cytostatic drugs. | Cancer biology & therapy 20050101 |
| [Antiviral action of membranotropic compounds modified by adamantane and norbornene pharmacophores exerted on different HIV-1 strains]. | Molekuliarnaia genetika, mikrobiologiia i virusologiia 20050101 |
| The effect of ladasten on gene expression in the rat brain. | Doklady. Biochemistry and biophysics 20050101 |
| [Studying the mechanisms of ladasten action]. | Eksperimental'naia i klinicheskaia farmakologiia 20050101 |
| [Effect of ladasten on reproduction function in male rats]. | Eksperimental'naia i klinicheskaia farmakologiia 20050101 |
| The GLP-1 system as a therapeutic target. | Annals of medicine 20050101 |
| Small molecule transcription factor mimic. | Journal of the American Chemical Society 20041215 |
| Effects of U-37883A on intracellular Ca2+ -activated large-conductance K+ channels in pig proximal urethral myocytes. | European journal of pharmacology 20041203 |
| Neurotensin receptor antagonist SR 142948A alters Fos expression and extrapyramidal side effect profile of typical and atypical antipsychotic drugs. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20041201 |
| Cross polarization, radio frequency field homogeneity, and circuit balancing in high field solid state NMR probes. | Journal of magnetic resonance (San Diego, Calif. : 1997) 20041201 |
| Twelve- and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 in metformin-treated patients with type 2 diabetes. | Diabetes care 20041201 |
| Novel adamantylated pyrimidines and their preliminary biological evaluations. | Farmaco (Societa chimica italiana : 1989) 20041201 |
| Evaluation of comparative cytochrome P450 2B4 model by photoaffinity labeling. | General physiology and biophysics 20041201 |
| Synthesis of rigid multivalent scaffolds based on adamantane. | Organic letters 20041125 |
| Polymer bilayer formation due to specific interactions between beta-cyclodextrin and adamantane: a surface force study. | Langmuir : the ACS journal of surfaces and colloids 20041123 |
| Conformational states of cytochrome P450cam revealed by trapping of synthetic molecular wires. | Journal of molecular biology 20041119 |
| Azaadamantane benzamide 5-HT4 agonists: gastrointestinal prokinetic SC-54750. | Bioorganic & medicinal chemistry letters 20041115 |
| Synthesis of 61-bis(1-adamantylcarbamoyl)-1,2-methano[60]fullerene and its antagonistic effect on haloperidol-induced catalepsy in mice. | Bioorganic & medicinal chemistry letters 20041115 |
| Oxazatricyclic noradamantanes: stereocontrolled synthesis of functionalized scopolines, related cage molecules, and drug leads. | Organic letters 20041111 |
| Non-empirical calculations of NMR indirect carbon-carbon coupling constants. Part 10--carbocages. | Magnetic resonance in chemistry : MRC 20041101 |
| (-)-Adamantyl-delta8-tetrahydrocannabinol (AM-411), a selective cannabinoid CB1 receptor agonist: effects on open-field behaviors and antagonism by SR-141716 in rats. | Behavioural pharmacology 20041101 |
| Activation of A3 adenosine receptors attenuates lung injury after in vivo reperfusion. | Anesthesiology 20041101 |
| Sigma receptor ligands: applications in inflammation and oncology. | Current opinion in investigational drugs (London, England : 2000) 20041101 |
| Cellular and pharmacological bases of the antitumor activity of a novel adamantyl retinoid, ST1926. | Journal of chemotherapy (Florence, Italy) 20041101 |
| Negative feedback regulation of nigrostriatal dopamine release: mediation by striatal D1 receptors. | The Journal of pharmacology and experimental therapeutics 20041001 |
| LAF-237 (Novartis). | Current opinion in investigational drugs (London, England : 2000) 20041001 |
| Adamantylsulfanyl- and N-adamantylcarboxamido-derivatives of heterocycles and phenols: synthesis, crystal structure, tumor necrosis factor-alpha production-enhancing properties, and theoretical considerations. | Chemistry & biodiversity 20041001 |
| The hydrophilic phosphatriazaadamantane ligand in the development of H2 production electrocatalysts: iron hydrogenase model complexes. | Journal of the American Chemical Society 20040929 |
| Topological analysis of electron densities: is the presence of an atomic interaction line in an equilibrium geometry a sufficient condition for the existence of a chemical bond? | Chemistry (Weinheim an der Bergstrasse, Germany) 20040920 |
| [A novel microbeads-based chemiluminescence immunoassay for detecting human thyrotropin]. | Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20040901 |
| 6-[2-(adamantylidene)-hydroxybenzoxazole]-O-sulfamate, a steroid sulfatase inhibitor for the treatment of androgen- and estrogen-dependent diseases. | The Journal of steroid biochemistry and molecular biology 20040901 |
| Immobilization of a (dextran-adamantane-COOH) polymer onto beta-cyclodextrin-modified silica. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040825 |
| 2-(1-adamantyl)-4-(thio)chromenone-6-carboxylic acids: potent reversible inhibitors of human steroid sulfatase. | Journal of medicinal chemistry 20040812 |
| Membrane permeability related physicochemical properties of a novel gamma-secretase inhibitor. | International journal of pharmaceutics 20040806 |
| In vitro and in vivo growth inhibition and G1 arrest in human cancer cell lines by diaminophenyladamantane derivatives. | Anti-cancer drugs 20040801 |
| Targeted delivery of RNA-cleaving DNA enzyme (DNAzyme) to tumor tissue by transferrin-modified, cyclodextrin-based particles. | Cancer biology & therapy 20040701 |
| Blockade of neurotensin receptors affects differently hypo-locomotion and catalepsy induced by haloperidol in mice. | Neuropharmacology 20040701 |
| Inhibition of glycolipid biosynthesis by N-(5-adamantane-1-yl-methoxy-pentyl)-deoxynojirimycin protects against the inflammatory response in hapten-induced colitis. | International immunopharmacology 20040701 |
| Antagonist analogue of 6-[3'-(1-adamantyl)-4'-hydroxyphenyl]-2-naphthalenecarboxylic acid (AHPN) family of apoptosis inducers that effectively blocks AHPN-induced apoptosis but not cell-cycle arrest. | Journal of medicinal chemistry 20040701 |
| Vibrational frequencies and structural determination of adamantane. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040701 |
| Photochemical patterning of a self-assembled monolayer of 7-diazomethylcarbonyl-2,4,9-trithiaadmantane on gold films via Wolff rearrangement. | Langmuir : the ACS journal of surfaces and colloids 20040608 |
| Photochemical preparation of 1,3,5,7-tetracyanoadamantane and its conversion to 1,3,5,7-tetrakis(aminomethyl)adamantane. | Organic letters 20040527 |
| Inhibition of dipeptidyl peptidase-4 reduces glycemia, sustains insulin levels, and reduces glucagon levels in type 2 diabetes. | The Journal of clinical endocrinology and metabolism 20040501 |
| Computational study of the conformational preferences of the (R)-8-amino-pentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecane-8-carboxylic acid monopeptide. | Journal of peptide science : an official publication of the European Peptide Society 20040501 |
| Combination of paclitaxel and nitric oxide as a novel treatment for the reduction of restenosis. | Journal of medicinal chemistry 20040422 |
| A wrench-shaped synthetic molecule that modulates a transcription factor-coactivator interaction. | Journal of the American Chemical Society 20040324 |
| Gramicidin-based channel systems for the detection of protein-ligand interaction. | Bioorganic & medicinal chemistry 20040315 |
| Apoptosis signaling by the novel compound 3-Cl-AHPC involves increased EGFR proteolysis and accompanying decreased phosphatidylinositol 3-kinase and AKT kinase activities. | Oncogene 20040311 |
| Induction of apoptosis and stress response in ovarian carcinoma cell lines treated with ST1926, an atypical retinoid. | Cell death and differentiation 20040301 |
| Molecular analysis of the subtype-selective inhibition of cloned KATP channels by PNU-37883A. | British journal of pharmacology 20040301 |
| High-resolution NMR imaging of objects with dipolar-broadened spectra. | Journal of magnetic resonance (San Diego, Calif. : 1997) 20040301 |
| Bowdichine, a new diaza-adamantane alkaloid from Bowdichia virgilioides. | Journal of Asian natural products research 20040301 |
| Pruritus-associated response mediated by cutaneous histamine H3 receptors. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040301 |
| Induction of growth inhibition and G1 arrest in human cancer cell lines by relatively low-toxic diamantane derivatives. | Anti-cancer drugs 20040301 |
| Synthesis of well-defined tower-shaped 1,3,5-trisubstituted adamantanes incorporating a macrocyclic trilactam ring system. | The Journal of organic chemistry 20040220 |
| Induction of apoptosis in human leukemia cells by the tyrosine kinase inhibitor adaphostin proceeds through a RAF-1/MEK/ERK- and AKT-dependent process. | Oncogene 20040219 |
| Comparison of the anticonvulsive activities of organic mono- and dications with their abilities to inhibit NMDA and AMPA glutamate receptors. | Neuroscience and behavioral physiology 20040201 |
| ST1926, a novel and orally active retinoid-related molecule inducing apoptosis in myeloid leukemia cells: modulation of intracellular calcium homeostasis. | Blood 20040101 |
| [Estimation of the protective effect of the novel potential antiparkinsonian agent himantane against MPTP neurotoxicity]. | Eksperimental'naia i klinicheskaia farmakologiia 20040101 |
| Medium effect on the enzymatically triggered electron-exchange luminescence of the biologically important dioxetane. | Doklady. Biochemistry and biophysics 20040101 |
| Neurotensin depolarizes globus pallidus neurons in rats via neurotensin type-1 receptor. | Neuroscience 20040101 |
| [Effect of ladasten on the proteinase C activity in the rat brain cells]. | Eksperimental'naia i klinicheskaia farmakologiia 20040101 |
| [Comparative study of neurophysiological effects of adamantane derivatives in the experimental parkinsonism model]. | Eksperimental'naia i klinicheskaia farmakologiia 20040101 |
| [The effect of ladasten on the activity of cAMP-dependent protein kinases and the phosphorylation of proteins in brain cells of rats]. | Eksperimental'naia i klinicheskaia farmakologiia 20040101 |
| [Ladasten induces the expression of genes regulating dopamine biosynthesis in various structures of rat brain]. | Eksperimental'naia i klinicheskaia farmakologiia 20040101 |
| [The effect of ladasten on the activation-induced expression of Fas receptor on T-lymphocytes and their sensitivity to Fas-induced apoptosis]. | Eksperimental'naia i klinicheskaia farmakologiia 20040101 |
| [The effect of long-term administration of isatin and himantan to mice on sensitivity of brain monoamine oxidase B to inhibition by deprenyl in vivo and in vitro]. | Biomeditsinskaia khimiia 20040101 |
| [The effect of hemantane on the generative function and gonad morphology in rats]. | Eksperimental'naia i klinicheskaia farmakologiia 20040101 |
| Synthesis and antibacterial activity of adamantyl substituted pyrimidines. | Acta poloniae pharmaceutica 20040101 |
| Electrochemical gene detection by using adamantyl naphthalene diimide coupled with ferrocenyl-beta-cyclodextrin. | Nucleic acids symposium series (2004) 20040101 |
| Involvement of reactive oxygen species in adaphostin-induced cytotoxicity in human leukemia cells. | Blood 20031215 |
| Hit-to-Lead studies: the discovery of potent adamantane amide P2X7 receptor antagonists. | Bioorganic & medicinal chemistry letters 20031117 |
| Study of in vitro and in vivo effects of 1,6-Bis[4-(4-amino-3-hydroxyphenoxy)phenyl]diamantane (DPD), a novel cytostatic and differentiation inducing agent, on human colon cancer cells. | British journal of cancer 20031117 |
| Induction of apoptosis in retinoid-refractory acute myelogenous leukemia by a novel AHPN analog. | Blood 20031115 |
| An application of the XiX decoupling for solid state 13C NMR with mobile samples. | Journal of magnetic resonance (San Diego, Calif. : 1997) 20031101 |
| Entrapment of peptidoglycans and adamantyltripeptides into liposomes: an HPLC assay for determination of encapsulation efficiency. | Journal of liposome research 20031101 |
| A system of protein target sequences for anti-RNA-viral chemotherapy by a vitamin B6-derived zinc-chelating trioxa-adamantane-triol. | Bioorganic & medicinal chemistry 20031015 |
| Determination of drug synergism between the tyrosine kinase inhibitors NSC 680410 (adaphostin) and/or STI571 (imatinib mesylate, Gleevec) with cytotoxic drugs against human leukemia cell lines. | Cancer chemotherapy and pharmacology 20031001 |
| Modified field amplification sample injection for micellar electrokinetic chromatography of neutral compounds with amino-substituted cyclodextrin as carrier and 1-adamantanecarboxylate as displacer. | Journal of chromatography. A 20030926 |
| Synthesis and antioxidant activity evaluation of novel antiparkinsonian agents, aminoadamantane derivatives of nitroxyl free radical. | Bioorganic & medicinal chemistry 20030805 |
| Theoretical analysis of a carbon-carbon dimer placement tool for diamond mechanosynthesis. | Journal of nanoscience and nanotechnology 20030801 |
| Synthesis of 1-boraadamantaneamine derivatives with selective astrocyte vs C6 glioma antiproliferative activity. A novel class of anti-hepatitis C agents with potential to bind CD81. | Journal of medicinal chemistry 20030703 |
| Noncompetitive antagonist binding sites in the torpedo nicotinic acetylcholine receptor ion channel. Structure-activity relationship studies using adamantane derivatives. | Biochemistry 20030624 |
| 1-[[(3-hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: a potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties. | Journal of medicinal chemistry 20030619 |
| Nanoscale tripodal 1,3,5,7-tetrasubstituted adamantanes for AFM applications. | The Journal of organic chemistry 20030613 |
| Chemical shift referencing in MAS solid state NMR. | Journal of magnetic resonance (San Diego, Calif. : 1997) 20030601 |
| 1-Azaadamantanes: pharmacological applications and synthetic approaches. | Current medicinal chemistry. Cardiovascular and hematological agents 20030601 |
| Spiro[pyrrolidine-2,2'-adamantanes]: synthesis, anti-influenza virus activity and conformational properties. | Bioorganic & medicinal chemistry letters 20030519 |
| [3H]R214127: a novel high-affinity radioligand for the mGlu1 receptor reveals a common binding site shared by multiple allosteric antagonists. | Molecular pharmacology 20030501 |
| A gene-expression inhibitor that targets an alpha-helix-mediated protein interaction. | Journal of the American Chemical Society 20030430 |
| A spin labelling study of immunomodulating peptidoglycan monomer and adamantyltripeptides entrapped into liposomes. | Biochimica et biophysica acta 20030401 |
| Twisted amide reduction under Wolff-Kishner conditions: synthesis of a benzo-1-aza-adamantane derivative. | Journal of the American Chemical Society 20030319 |
| A novel atypical retinoid endowed with proapoptotic and antitumor activity. | Journal of medicinal chemistry 20030313 |
| Reactivities of organic phase biosensors: 6. Square-wave and differential pulse studies of genetically engineered cytochrome P450(cam) (CYP101) bioelectrodes in selected solvents. | Biosensors & bioelectronics 20030301 |
| Studies of the structure of glutamate receptor ion channels and the mechanisms of their blockade by organic cations. | Neuroscience and behavioral physiology 20030301 |
| 3'Sulfogalactolipid binding specifically inhibits Hsp70 ATPase activity in vitro. | Biochemistry 20030218 |
| [Treatment of influenza in children]. | Zhonghua er ke za zhi = Chinese journal of pediatrics 20030201 |
| Effects of cholecystokinin tetrapeptide (CCK(4)) and of anxiolytic drugs on GABA outflow from the cerebral cortex of freely moving rats. | Neurochemistry international 20030101 |
| Microwave-assisted synthesis of O'-adamantylated uracil-derived nucleosides. | Nucleosides, nucleotides & nucleic acids 20030101 |
| [Evaluation of the prolonged immunotropic effect of the potential antiparkinson agent himantane]. | Eksperimental'naia i klinicheskaia farmakologiia 20030101 |
| [Comparative study of the distribution of 3[H]-himantane in the brain structures and the thymus of rats]. | Eksperimental'naia i klinicheskaia farmakologiia 20030101 |
| [HIV-inhibiting activity of polyanion matrices and related substances containing adamantane and norbornene pharmacophores]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101 |
| An adamantanone derivative that is an original modulator of redox processes in the cytochrome P-450 system can serve as an effective remedy against obliterating angiopathy of lower extremities. | Doklady. Biochemistry and biophysics 20030101 |
| [Structure and antiviral activity of adamantane-containing polymer preparation]. | Voprosy virusologii 20030101 |
| Transferrin-containing, cyclodextrin polymer-based particles for tumor-targeted gene delivery. | Bioconjugate chemistry 20030101 |
| [Effect of a new antiparkinsonian drug himantane on monoamine oxidase activity]. | Eksperimental'naia i klinicheskaia farmakologiia 20030101 |
| [Effect of himantane on the rat embryo development]. | Eksperimental'naia i klinicheskaia farmakologiia 20030101 |
| Role of protein and substrate dynamics in catalysis by Pseudomonas putida cytochrome P450cam. | Biochemistry 20021210 |
| SSR125329A, a high affinity sigma receptor ligand with potent anti-inflammatory properties. | European journal of pharmacology 20021205 |
| Crystal structures of dipeptides containing the Dmt-Tic pharmacophore. | Journal of medicinal chemistry 20021205 |
| In vitro and in vivo evaluations of the tyrosine kinase inhibitor NSC 680410 against human leukemia and glioblastoma cell lines. | Cancer chemotherapy and pharmacology 20021201 |
| Potassium-induced increase in renal kallikrein secretion is attenuated in dissected renal connecting tubules of young spontaneously hypertensive rats. | International immunopharmacology 20021201 |
| Synthesis and binding affinities of 5-(3-pyridinyl)- and 5-(3-quinolinyl)-4-azahomoadamantanes to alpha7 nicotinic acetylcholine receptors. | Farmaco (Societa chimica italiana : 1989) 20021201 |
| Solid-state and solution studies of a tetrameric capsule and its guests. | Angewandte Chemie (International ed. in English) 20021018 |
| Nanoscale 1,3,5,7-tetrasubstituted adamantanes and p-substituted tetraphenyl-methanes for AFM applications. | Organic letters 20021017 |
| A novel soluble analog of the HIV-1 fusion cofactor, globotriaosylceramide (Gb(3)), eliminates the cholesterol requirement for high affinity gp120/Gb(3) interaction. | Journal of lipid research 20021001 |
| Neuroprotective effects of a novel non-receptor-binding estrogen analogue: in vitro and in vivo analysis. | Stroke 20021001 |
| FTIR spectra and normal-mode analysis of a tetranuclear manganese adamantane-like complex in two electrochemically prepared oxidation states: relevance to the oxygen-evolving complex of photosystem II. | Journal of the American Chemical Society 20020918 |
| 2-Substituted 4-(thio)chromenone 6-O-sulfamates: potent inhibitors of human steroid sulfatase. | Journal of medicinal chemistry 20020912 |
| Fluorescent probes for cytochrome p450 structural characterization and inhibitor screening. | Journal of the American Chemical Society 20020904 |
| Stimulation of TNF-alpha production by 2-(1-adamantylamino)-6-methylpyridine (AdAMP) - a novel immunomodulator with potential application in tumour immunotherapy. | Cancer chemotherapy and pharmacology 20020901 |
| [Comparison of the anticonvulsant activity of organic mono- and di-cations and their potential to inhibit NMDA and AMPA glutamate receptors]. | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20020901 |
| Synthesis and antimicrobial activity of new adamantane derivatives III. | Farmaco (Societa chimica italiana : 1989) 20020801 |
| New selective inhibitors of cytochromes P450 2B and their application to antimutagenesis of tamoxifen. | Archives of biochemistry and biophysics 20020701 |
| Structural properties of a series of photochromic fluorinated indolylfulgides. | Acta crystallographica. Section C, Crystal structure communications 20020701 |
| Neurotensin phase-shifts the firing rate rhythm of neurons in the rat suprachiasmatic nuclei in vitro. | The European journal of neuroscience 20020701 |
| Novel selective PDE4 inhibitors. 3. In vivo antiinflammatory activity of a new series of N-substituted cis-tetra- and cis-hexahydrophthalazinones. | Journal of medicinal chemistry 20020606 |
| Novel selective phosphodiesterase (PDE4) inhibitors. 4. Resolution, absolute configuration, and PDE4 inhibitory activity of cis-tetra- and cis-hexahydrophthalazinones. | Journal of medicinal chemistry 20020606 |
| Dimethyladamantylmaleimide-induced in vitro and in vivo growth inhibition of human colon cancer Colo205 cells. | Anti-cancer drugs 20020601 |
| Anti-viral drugs in continuous ambulatory peritoneal dialysis (CAPD). | Minerva urologica e nefrologica = The Italian journal of urology and nephrology 20020601 |
| The neurotensin receptor antagonist SR 142948A blocks the efflux of dopamine evoked in nucleus accumbens by neurotensin ejection into the ventral tegmental area. | Naunyn-Schmiedeberg's archives of pharmacology 20020601 |
| Evaluation of GluR2 subunit involvement in AMPA receptor function of neonatal rat hypoglossal motoneurons. | The European journal of neuroscience 20020601 |
| A preliminary approach to nonenolizable beta,beta-tricarbonyls: assembly of a hyperevolutin prototype. | The Journal of organic chemistry 20020503 |
| Effects of neurotensin receptor antagonism on latent inhibition in Sprague-Dawley rats. | Psychopharmacology 20020501 |
| The estrogen receptor is not essential for all estrogen neuroprotection: new evidence from a new analog. | Neurobiology of disease 20020401 |
| Adamantyl tenocyclidines--adjuvant therapy in poisoning with organophosphorus compounds and carbamates. | Archives of toxicology 20020401 |
| Synthesis and antiviral activity evaluation of some new 6-substituted 3-(1-adamantyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles. | Farmaco (Societa chimica italiana : 1989) 20020301 |
| Role of kallikrein-kininogen system in insulin-stimulated glucose transport after muscle contractions. | Journal of applied physiology (Bethesda, Md. : 1985) 20020201 |
| Unique property of some synthetic retinoids: activation of the aryl hydrocarbon receptor pathway. | Molecular pharmacology 20020201 |
| The actions of a D-1 agonist in MPTP treated primates show dependence on both D-1 and D-2 receptor function and tolerance on repeated administration. | Journal of neural transmission (Vienna, Austria : 1996) 20020201 |
| Effects of the incorporation of IBTM beta-turn mimetics into the dipeptoid CCK(1) receptor agonist PD 170292. | Bioorganic & medicinal chemistry letters 20020121 |
| Effects of the Bcr/abl kinase inhibitors STI571 and adaphostin (NSC 680410) on chronic myelogenous leukemia cells in vitro. | Blood 20020115 |
| The influence of substitution at aromatic part of 1,2,3,4-tetrahydroisoquinoline on in vitro and in vivo 5-HT(1A)/5-HT(2A) receptor activities of its 1-adamantoyloaminoalkyl derivatives. | Bioorganic & medicinal chemistry 20020101 |
| Comparison of interactions of D1-like agonists, SKF 81297, SKF 82958 and A-77636, with cocaine: locomotor activity and drug discrimination studies in rodents. | Psychopharmacology 20020101 |
| Development of a nonviral gene delivery vehicle for systemic application. | Bioconjugate chemistry 20020101 |
| [Comparison of anti-amnesia properties of NMDA-receptor 'fast' blockers and polyamines]. | Eksperimental'naia i klinicheskaia farmakologiia 20020101 |
| The effects of diphenhydramine and SR142948A on periaqueductal gray neurons and on the interactions between the medial preoptic nucleus and the periaqueductal gray. | Neuroscience 20020101 |
| Effects of some trivalent metal ions on the fluoride-induced chemiluminescence from a phenylphosphate-substituted dioxetane Lumigen PPD. | Luminescence : the journal of biological and chemical luminescence 20020101 |
| Synthesis and antimicrobial activity evaluation of some new adamantane derivatives. | Arzneimittel-Forschung 20020101 |
| [Effect of ladasten on proliferative activity and apoptosis in peripheral blood T-lymphocytes ]. | Eksperimental'naia i klinicheskaia farmakologiia 20020101 |
| Synthesis and biological properties of S-adamantylated heterocyclic compounds. | Acta poloniae pharmaceutica 20020101 |
| Synthesis of adamantyl naphthalene diimide and its interaction with double stranded DNA. | Nucleic acids research. Supplement (2001) 20020101 |
| Rapid determination of soluble epoxide hydrolase inhibitors in rat hepatic microsomes by high-performance liquid chromatography with electrospray tandem mass spectrometry. | Analytical biochemistry 20011215 |
| Effects of cholecystokinin tetrapeptide (CCK(4)) and anxiolytic drugs on the electrically evoked [(3)H]5-hydroxytryptamine outflow from rat cortical slices. | Brain research 20011213 |
| Differential responses to ATPgammaS in the mesenteric and hindlimb vascular bed of the cat. | Life sciences 20011012 |
| Metal-directed formation of three-dimensional M(3)L(2) trigonal-bipyramidal cages. | Organic letters 20011004 |
| Analysis of responses to hAmylin, hCGRP, and hADM in isolated resistance arteries from the mesenteric vascular bed of the rat. | Peptides 20010901 |
| Switching of a macromolecular helicity for visual distinction of molecular recognition events. | Journal of the American Chemical Society 20010822 |
| [Structure of glutamate receptor ion channels and mechanisms of their blockade by organic cations]. | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20010801 |
| The effect of neighboring 1- and 2-adamantyl group substitution on the conformations and stereodynamics of N-methylpiperidine. Dynamic NMR spectroscopy and molecular mechanics calculations. | The Journal of organic chemistry 20010727 |
| Sn-zeolite beta as a heterogeneous chemoselective catalyst for Baeyer-Villiger oxidations. | Nature 20010726 |
| Interactions of synthetic estrogens with human estrogen receptors. | The Journal of endocrinology 20010701 |
| Synthesis and modulation of cytokine production by two new adamantane substituted acyclic desmuramyldipeptide analogs. | Die Pharmazie 20010701 |
| K(ATP) channels predominantly regulate conduit vessel tone in normoxic cat pulmonary arteries in vivo. | European journal of pharmacology 20010622 |
| Neurotensin excitation of serotonergic neurons in the rat nucleus raphe magnus: ionic and molecular mechanisms. | Neuropharmacology 20010601 |
| Endogenous neurotensin down-regulates dopamine efflux in the nucleus accumbens as revealed by SR-142948A, a selective neurotensin receptor antagonist. | Journal of neurochemistry 20010601 |
| Inhibition of human multidrug resistance P-glycoprotein 1 by analogues of a potent delta-opioid antagonist. | Brain research 20010525 |
| Adamantylaminopyrimidines and -pyridines are potent inducers of tumor necrosis factor-alpha. | Bioorganic & medicinal chemistry letters 20010507 |
| Nonpeptide cholecystokinin-2 receptor agonists. | Journal of medicinal chemistry 20010412 |
| Rewarding and locomotor-activating effects of direct dopamine receptor agonists are augmented by chronic food restriction in rats. | Psychopharmacology 20010401 |
| A high pressure FT-IR spectroscopic study of phase transitions in 1-chloro- and 1-bromoadamantane. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20010401 |
| Comparative effects of scopolamine and quinpirole on the striatal fos expression induced by stimulation of D(1) dopamine receptors in the rat. | Brain research 20010302 |
| Biorelevant dissolution testing to predict the plasma profile of lipophilic drugs after oral administration. | Pharmaceutical research 20010301 |
| Capture of a single molecule in a nanocavity. | Science (New York, N.Y.) 20010126 |
| Enhanced neurotensin neurotransmission is involved in the clinically relevant behavioral effects of antipsychotic drugs: evidence from animal models of sensorimotor gating. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20010115 |
| New analogues of bradykinin containing a conformationally restricted dipeptide fragment in their molecules. | The journal of peptide research : official journal of the American Peptide Society 20010101 |
| An optimized method for the chemiluminescent detection of alkaline phosphatase levels during osteodifferentiation by bone morphogenetic protein 2. | Journal of cellular biochemistry 20010101 |
| Organic halide electroreduction on silver. | Annali di chimica 20010101 |
| Pharmacological analysis of the subunit composition of the AMPA receptor in hippocampal neurons. | Neuroscience and behavioral physiology 20010101 |
| Therapeutical effect of modified adamantane copolymer compounds: study of molecular mechanisms. | Acta biochimica Polonica 20010101 |
| [Effect of the potential antiparkinsonian agent adamantane derivative on ion channels of NMDA glutamate receptors]. | Eksperimental'naia i klinicheskaia farmakologiia 20010101 |
| [Immunotropic activity of a potential antiparkinson agent himantane]. | Eksperimental'naia i klinicheskaia farmakologiia 20010101 |
| Effect of adamantanone derivative possessing anti-HIV properties on the redox processes in the cytochrome P-450 system. | Doklady. Biochemistry and biophysics 20010101 |
| [Effect of the new potential anti-Parkinson agent, hymantane, on levels of monoamines and their metabolites in rat striatum (a microdialysis study)]. | Eksperimental'naia i klinicheskaia farmakologiia 20010101 |
| Synthesis, structure and tumour necrosis factor-alpha production-enhancing properties of novel adamantylamino heterocyclic derivatives. | Anti-cancer drug design 20010101 |
| Neurotensin modulates the electrical activity of frog pituitary melanotropes via activation of a G-protein-coupled receptor pharmacologically related to both the NTS1 and nts2 receptors of mammals. | Neuroendocrinology 20001201 |
| Synthesis, antitumor activity, and anti-HIV-1 testing of certain heterocyclic systems containing an adamantane nucleus. | Archiv der Pharmazie 20001001 |
| [A comparative study of the central H-cholinergic-blocking and NMDA-blocking actions of MK-801, memantin, amantadine, pyrilen and IEM-1754 in experiments on intact rats]. | Eksperimental'naia i klinicheskaia farmakologiia 20000101 |
| The role of cholecystokinin (CCK), CCK-A or CCK-B receptor antagonists in the spontaneous preference for drugs of abuse (alcohol or cocaine) in naive rats. | Methods and findings in experimental and clinical pharmacology 19981001 |
| How to overcome resistance of influenza A viruses against adamantane derivatives. | Antiviral research 19980201 |
| Second generation 'peptoid' CCK-B receptor antagonists: identification and development of N-(adamantyloxycarbonyl)-alpha-methyl-(R)-tryptophan derivative (CI-1015) with an improved pharmacokinetic profile. | Journal of medicinal chemistry 19980101 |
| Anticonvulsant phenytoinergic pharmacophores and anti-HIV activity--preliminary evidence for the dual requirement of the 4-aminophthalimide platform and the N-(1-adamantyl) substitution for antiviral properties. | Life sciences 19980101 |
| Kinins are implicated of the hypotensive effect of acidic fibroblast growth factor. | European journal of medical research 19970728 |
| Biochemical and pharmacological activities of SR 142948A, a new potent neurotensin receptor antagonist. | The Journal of pharmacology and experimental therapeutics 19970201 |
| Synthesis and antiviral activity evaluation of some new aminoadamantane derivatives. 2. | Journal of medicinal chemistry 19960816 |
| Selective in vivo antagonism of pinacidil-induced hypotension by the guanidine U37883A in anesthetized rats. | Pharmacology 19941201 |
| Synthesis and antiviral activity evaluation of some aminoadamantane derivatives. | Journal of medicinal chemistry 19940902 |
| New C-protective group for peptide synthesis. Application of 2-(1-adamantyl)-propanol-2 esters. | International journal of peptide and protein research 19930901 |
| Synthesis, antifungal, antibacterial and antiviral effects of some adamantaneketoxime ethers. | Farmaco (Societa chimica italiana : 1989) 19930801 |
| Microbial oxidation of adamantanone by Pseudomonas putida carrying the camphor catabolic plasmid. | Biochemical and biophysical research communications 19920814 |
| Isolation of a heptapeptide Val-Val-Tyr-Pro-Trp-Thr-Gln (valorphin) with some opiate activity. | International journal of peptide and protein research 19920601 |
| Synthesis and antiviral activity of metabolites of rimantadine. | Journal of medicinal chemistry 19900701 |
| Rimantadine and seizures. | Annals of internal medicine 19890215 |
| Combined interferon-alpha 2, rimantadine hydrochloride, and ribavirin inhibition of influenza virus replication in vitro. | Antimicrobial agents and chemotherapy 19840101 |
| Comparative toxicity of amantadine hydrochloride and rimantadine hydrochloride in healthy adults. | Antimicrobial agents and chemotherapy 19810201 |
| Influence of membrane (M) protein on influenza A virus virion transcriptase activity in vitro and its susceptibility to rimantadine. | Journal of virology 19800201 |
| Adamantylthiourea derivatives as antiviral agents. | Journal of medicinal chemistry 19790801 |
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