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2281-74-5 | 1,3-thiazolidin-4-one
CAS No: 2281-74-5 Catalog No: AG01DZ9G MDL No:MFCD17015366
Product Description
Catalog Number:
AG01DZ9G
Chemical Name:
1,3-thiazolidin-4-one
CAS Number:
2281-74-5
Molecular Formula:
C3H5NOS
Molecular Weight:
103.1429
MDL Number:
MFCD17015366
IUPAC Name:
1,3-thiazolidin-4-one
InChI:
InChI=1S/C3H5NOS/c5-3-1-6-2-4-3/h1-2H2,(H,4,5)
InChI Key:
NOLHRFLIXVQPSZ-UHFFFAOYSA-N
SMILES:
C1SCNC1=O
Properties
Complexity:
73.2
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
103.009g/mol
Formal Charge:
0
Heavy Atom Count:
6
Hydrogen Bond Acceptor Count:
2
Hydrogen Bond Donor Count:
1
Isotope Atom Count:
0
Molecular Weight:
103.139g/mol
Monoisotopic Mass:
103.009g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
54.4A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.1
Literature
| Title | Journal |
|---|---|
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| (Z)-3-p-Tolyl-2-(p-tolyl-imino)-1,3-thia-zolidin-4-one. | Acta crystallographica. Section E, Structure reports online 20120401 |
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| Synthesis and in vitro antimicrobial study of 4-thiazolidinone containing sulfanilamide. | Acta poloniae pharmaceutica 20120101 |
| Efficient regioselective three-component domino synthesis of 3-(1,2,4-Triazol-5-yl)-1,3-thiazolidin-4-ones as potent antifungal and antituberculosis agents. | Archiv der Pharmazie 20111201 |
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| Anti-stroke profile of thiazolidin-4-one derivatives in focal cerebral ischemia model in rat. | Chemical biology & drug design 20110901 |
| Quantitative structure-retention relationship of new N-substituted 2-alkylidene-4-oxothiazolidines. | Journal of separation science 20110901 |
| Microwave-assisted synthesis of dinucleoside analogues containing a thiazolidin-4-one linkage via one-pot tandem Staudinger/aza-Wittig/cyclization. | Organic & biomolecular chemistry 20110821 |
| Thiazolidin-4-one and hydrazone derivatives of capric acid as possible anti-inflammatory, analgesic and hydrogen peroxide-scavenging agents. | Journal of enzyme inhibition and medicinal chemistry 20110801 |
| Design, synthesis and biological evaluation of novel 4-thiazolidinones containing indolin-2-one moiety as potential antitumor agent. | European journal of medicinal chemistry 20110801 |
| (5E)-5-(4-Meth-oxy-benzyl-idene)-2-(piperidin-1-yl)-1,3-thia-zol-4(5H)-one. | Acta crystallographica. Section E, Structure reports online 20110801 |
| 5-Benzyl-idene-3-phenyl-2-phenyl-imino-1,3-thia-zolidin-4-one. | Acta crystallographica. Section E, Structure reports online 20110701 |
| Evaluation of 3-(4'-(4″-fluorophenyl)-6'-phenylpyrimidin-2'-yl)-2-phenylthiazolidin-4-one for in vivo modulation of biomarkers of chemoprevention in the 7,12-dimethylbenz[a]anthracene-induced hamster buccal pouch carcinogenesis. | Journal of enzyme inhibition and medicinal chemistry 20110601 |
| Synthesis of some novel 2,5-disubstituted thiazolidinones from a long chain fatty acid as possible anti-inflammatory, analgesic and hydrogen peroxide scavenging agents. | Journal of enzyme inhibition and medicinal chemistry 20110401 |
| N-[2-(4-Chloro-phen-yl)-5-methyl-4-oxo-1,3-thia-zolidin-3-yl]pyridine-3-carboxamide. | Acta crystallographica. Section E, Structure reports online 20110401 |
| N-[2-(4-Bromo-phen-yl)-5-methyl-4-oxo-1,3-thia-zolidin-3-yl]pyridine-3-carboxamide. | Acta crystallographica. Section E, Structure reports online 20110401 |
| Synthesis, characterization, antioxidant and antitumor evaluation of some new thiazolidine and thiazolidinone derivatives. | Archiv der Pharmazie 20110301 |
| N-[5-Methyl-2-(2-nitro-phen-yl)-4-oxo-1,3-thia-zolidin-3-yl]pyridine-3-carboxamide monohydrate. | Acta crystallographica. Section E, Structure reports online 20110201 |
| 3D-QSAR studies on thiazolidin-4-one S1P₁receptor agonists by CoMFA and CoMSIA. | International journal of molecular sciences 20110101 |
| Synthesis and antimicrobial study of linked heterocyclics containing Pyrazole-pyrimidine-thiazolidin-4-one. | Chemical & pharmaceutical bulletin 20101201 |
| Synthesis and anticonvulsant activity of certain substituted furochromone, benzofuran and flavone derivatives. | Chemical & pharmaceutical bulletin 20100901 |
| Quantitative structure activity relationship (QSAR) analysis of substituted 4-oxothiazolidines and 5-arylidines as lipoxygenase inhibitors. | Mini reviews in medicinal chemistry 20100701 |
| N-[(2S)-2-(4-Bromo-phen-yl)-4-oxo-1,3-thia-zolidin-3-yl]pyridine-3-carboxamide. | Acta crystallographica. Section E, Structure reports online 20100701 |
| 3-Butyl-2-phenyl-1,3-thia-zolidine-1,4-dione. | Acta crystallographica. Section E, Structure reports online 20100601 |
| Anti-parasitic action and elimination of intracellular Toxoplasma gondii in the presence of novel thiosemicarbazone and its 4-thiazolidinone derivatives. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20100201 |
| Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. | Bioorganic & medicinal chemistry 20100101 |
| Synthesis and antimicrobial evaluation of new 3-alkyl/aryl-2-[((alpha,alpha-diphenyl-alpha-hydroxy)acetyl)hydrazono]-5-methyl-4-thiazolidinones. | Archives of pharmacal research 20100101 |
| Synthesis and microbial studies of (4-oxo-thiazolidinyl) sulfonamides bearing quinazolin-4(3H)ones. | Acta poloniae pharmaceutica 20100101 |
| New 4-thiazolidinones of nicotinic acid with 2-Amino-6-methylbenzothiazole and their biological activity. | Scientia pharmaceutica 20100101 |
| Studies of Antimicrobial Activities of some 4-Thiazolidinone Fused Pyrimidines, [1,5]-Benzodiazepines and their Oxygen Substituted Hydroxylamine Derivatives. | Indian journal of pharmaceutical sciences 20100101 |
| Synthesis and antimycobacterial activity of a novel series of isonicotinylhydrazide derivatives. | Archiv der Pharmazie 20091201 |
| 3-Cyclo-hexyl-2-thioxo-1,3-thia-zolidin-4-one. | Acta crystallographica. Section E, Structure reports online 20091201 |
| 4-(Pyrimidin-2-yl)-1-thia-4-aza-spiro-[4.5]decan-3-one. | Acta crystallographica. Section E, Structure reports online 20091201 |
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| N-[2-(6-Methyl-4-oxo-4H-chromen-3-yl)-4-oxothia-zolidin-3-yl]furan-2-carbox-amide N,N-dimethyl-formamide solvate. | Acta crystallographica. Section E, Structure reports online 20090801 |
| Regioselective synthesis of novel 3-alkoxy (phenyl) thiophosphorylamido-2-(per-O-acetylglycosyl-1'-imino)thiazolidine-4-one derivatives from O-alkyl N4-glycosyl(thiosemicarbazido)phosphonothioates. | Carbohydrate research 20090706 |
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| 2-(4-Chloro-phen-yl)-3-p-tolyl-1,3-thia-zolidin-4-one. | Acta crystallographica. Section E, Structure reports online 20090401 |
| 5-Arylidene-2-phenylimino-4-thiazolidinones as PTP1B and LMW-PTP inhibitors. | Bioorganic & medicinal chemistry 20090301 |
| CoMFA and CoMSIA studies on thiazolidin-4-one as anti-HIV-1 agents. | Journal of molecular graphics & modelling 20090201 |
| Design, synthesis and pharmacological screening of novel antihypertensive agents using hybrid approach. | Bioorganic & medicinal chemistry 20090101 |
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| Discovery of substituted sulfonamides and thiazolidin-4-one derivatives as agonists of human constitutive androstane receptor. | Biochemical pharmacology 20081115 |
| Autonomic nervous system and cardiovascular system. | Indian journal of pharmacology 20081001 |
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| Synthesis and evaluation of the antiinflammatory activity of N-[2-(3,5-di-tert-butyl-4-hydroxyphenyl)-4-oxo-thiazolidin-3-yl]-nicotinamide. | Arzneimittel-Forschung 20070101 |
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| Synthesis and QSAR studies on thiazolidinones as anti-HIV agents. | Combinatorial chemistry & high throughput screening 20050801 |
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| Discovery of 2-arylthiazolidine-4-carboxylic acid amides as a new class of cytotoxic agents for prostate cancer. | Journal of medicinal chemistry 20050407 |
| Thiazolidin-4-one formation. Mechanistic and synthetic aspects of the reaction of imines and mercaptoacetic acid under microwave and conventional heating. | Organic & biomolecular chemistry 20041007 |
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