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2243-81-4 | 1-Naphthamide
CAS No: 2243-81-4 Catalog No: AG003EJC MDL No:MFCD00014314
Product Description
Catalog Number:
AG003EJC
Chemical Name:
1-Naphthamide
CAS Number:
2243-81-4
Molecular Formula:
C11H9NO
Molecular Weight:
171.1953
MDL Number:
MFCD00014314
IUPAC Name:
naphthalene-1-carboxamide
InChI:
InChI=1S/C11H9NO/c12-11(13)10-7-3-5-8-4-1-2-6-9(8)10/h1-7H,(H2,12,13)
InChI Key:
RMHJJUOPOWPRBP-UHFFFAOYSA-N
SMILES:
NC(=O)c1cccc2c1cccc2
NSC Number:
38871
Properties
Complexity:
202
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
171.068g/mol
Formal Charge:
0
Heavy Atom Count:
13
Hydrogen Bond Acceptor Count:
1
Hydrogen Bond Donor Count:
1
Isotope Atom Count:
0
Molecular Weight:
171.199g/mol
Monoisotopic Mass:
171.068g/mol
Rotatable Bond Count:
1
Topological Polar Surface Area:
43.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.4
Literature
| Title | Journal |
|---|---|
| Involvement of efflux mechanisms in biocide resistance of Campylobacter jejuni and Campylobacter coli. | Journal of medical microbiology 20120601 |
| Neoadjuvant chemotherapy modifies serum angiotensinase activities in women with breast cancer. | Maturitas 20120501 |
| Chiral discrimination of aliphatic amines and amino alcohols using NMR spectroscopy. | Magnetic resonance in chemistry : MRC 20120401 |
| First synthesis and anticancer activity of novel naphthoquinone amides. | European journal of medicinal chemistry 20120301 |
| Dual-functional gadolinium-based copper(II) probe for selective magnetic resonance imaging and fluorescence sensing. | Inorganic chemistry 20120220 |
| Synthesis and evaluation of non-basic inhibitors of urokinase-type plasminogen activator (uPA). | Bioorganic & medicinal chemistry 20120215 |
| Intracellular alkalinization induces cytosolic Ca2+ increases by inhibiting sarco/endoplasmic reticulum Ca2+-ATPase (SERCA). | PloS one 20120101 |
| Periodontal status in smokers and nonsmokers: a clinical, microbiological, and histopathological study. | International journal of dentistry 20120101 |
| Biochemical characterisation of prolyl aminopeptidase from shoots of triticale seedlings and its activity changes in response to suboptimal growth conditions. | Plant physiology and biochemistry : PPB 20111101 |
| Essential oils from Moroccan plants as potential chemosensitisers restoring antibiotic activity in resistant Gram-negative bacteria. | International journal of antimicrobial agents 20111001 |
| Asymmetric photocycloaddition of naphthamide with a diene using the provisional molecular chirality in a chiral crystal. | Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20110901 |
| Ethyl 2-[1,3-dioxo-6-(piperidin-1-yl)-2,3-dihydro-1H-benz[de]isoquinolin-2-yl]acetate. | Acta crystallographica. Section E, Structure reports online 20110701 |
| Structural basis for the recognition and cleavage of histone H3 by cathepsin L. | Nature communications 20110215 |
| Human dipeptidyl peptidase III: insights into ligand binding from a combined experimental and computational approach. | Journal of molecular recognition : JMR 20110101 |
| Anti-oxidant and Anti-hypercholesterolemic Activities of Wasabia japonica. | Evidence-based complementary and alternative medicine : eCAM 20101201 |
| A confocal study on the visualization of chromaffin cell secretory vesicles with fluorescent targeted probes and acidic dyes. | Journal of structural biology 20101201 |
| Purification and functional characterisation of rhiminopeptidase A, a novel aminopeptidase from the venom of Bitis gabonica rhinoceros. | PLoS neglected tropical diseases 20100801 |
| The calcium-mobilizing messenger nicotinic acid adenine dinucleotide phosphate participates in sperm activation by mediating the acrosome reaction. | The Journal of biological chemistry 20100611 |
| N-Methacryloyl-4-(piperidin-1-yl)-1,8-naphthalimide. | Acta crystallographica. Section E, Structure reports online 20100601 |
| Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2+) signaling and endolysosomal trafficking. | Current biology : CB 20100427 |
| Calcium signaling via two-pore channels: local or global, that is the question. | American journal of physiology. Cell physiology 20100301 |
| Pyrene-naftylamide bifluorophore for spectra-converting media. | Journal of fluorescence 20100101 |
| Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation. | PloS one 20100101 |
| A transcriptomic analysis of gene expression in the venom gland of the snake Bothrops alternatus (urutu). | BMC genomics 20100101 |
| Absolutely conserved tryptophan in M49 family of peptidases contributes to catalysis and binding of competitive inhibitors. | Bioorganic chemistry 20090601 |
| Neutral cysteine protease bleomycin hydrolase is essential for the breakdown of deiminated filaggrin into amino acids. | The Journal of biological chemistry 20090508 |
| Small molecules with potent osteogenic-inducing activity in osteoblast cells. | Bioorganic & medicinal chemistry letters 20090301 |
| A new type of neuron-specific aminopeptidase NAP-2 in rat brain synaptosomes. | Neurochemistry international 20081201 |
| Lysosomal targeting and trafficking of acid sphingomyelinase to lipid raft platforms in coronary endothelial cells. | Arteriosclerosis, thrombosis, and vascular biology 20081101 |
| 4-[(E)-2-Ferrocenylethen-yl]-1,8-naphthalic anhydride. | Acta crystallographica. Section E, Structure reports online 20080401 |
| Evaluation of a series of naphthamides as potent, orally active vascular endothelial growth factor receptor-2 tyrosine kinase inhibitors. | Journal of medicinal chemistry 20080327 |
| Naphthamides as novel and potent vascular endothelial growth factor receptor tyrosine kinase inhibitors: design, synthesis, and evaluation. | Journal of medicinal chemistry 20080327 |
| Utility of malignancy markers in fine-needle aspiration cytology of thyroid nodules: comparison of Hector Battifora mesothelial antigen-1, thyroid peroxidase and dipeptidyl aminopeptidase IV. | British journal of cancer 20080226 |
| N-(4-Amino-phen-yl)-1,8-naphthalimide hemihydrate. | Acta crystallographica. Section E, Structure reports online 20080101 |
| NAADP mobilizes calcium from the endoplasmic reticular Ca(2+) store in T-lymphocytes. | The Journal of biological chemistry 20070629 |
| Isolation, purification and characterization of a DPP-III homologue from goat brain. | Protein expression and purification 20070401 |
| Synthesis and in vitro binding studies of substituted piperidine naphthamides. Part II: Influence of the substitution on the benzyl moiety on the affinity for D2L, D4.2, and 5-HT2A receptors. | Bioorganic & medicinal chemistry letters 20070315 |
| Synthesis and in vitro binding studies of substituted piperidine naphthamides. Part I: Influence of the substitution on the basic nitrogen and the position of the amide on the affinity for D2L, D4.2, and 5-HT2A receptors. | Bioorganic & medicinal chemistry letters 20070315 |
| The lysosome or lysosome-related organelle may serve as a Ca2+ store in the boutons of hippocampal pyramidal cells. | Neuropharmacology 20070101 |
| Atrial angiotensinase activity in hypothyroid, euthyroid, and hyperthyroid rats. | Journal of cardiovascular pharmacology 20060901 |
| Characterization of proteolytic activities of Fusobacterium nucleatum. | Journal of endodontics 20060601 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Bioassay for the determination of the intra- and extracellular activity of aminopeptidases in immobilized tomato cells. | Chemistry & biodiversity 20060401 |
| Efficient remote axial-to-central chirality transfer in enantioselective SmI2-mediated reductive coupling of aldehydes with crotonates of atropisomeric 1-naphthamides. | The Journal of organic chemistry 20060317 |
| Calcium mobilization by nicotinic acid adenine dinucleotide phosphate (NAADP) in rat astrocytes. | Cell calcium 20060201 |
| Influence of thyroid disorders on kidney angiotensinase activity. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20060101 |
| Effect of calcium ions on enteropeptidase catalysis. | Biochemistry. Biokhimiia 20051001 |
| Asymmetric photocycloaddition in solution of a chiral crystallized naphthamide. | Angewandte Chemie (International ed. in English) 20050826 |
| Cation-independent mannose 6-phosphate and 78 kDa receptors for lysosomal enzyme targeting are located in different cell compartments. | Biochimica et biophysica acta 20050815 |
| Subcellular distribution of membrane-bound aminopeptidases in the human and rat brain. | Neuroscience letters 20050701 |
| Representative aminopeptidases and prolyl endopeptidase from murine macrophages: comparative activity levels in resident and elicited cells. | Biochemical pharmacology 20050515 |
| New synthesis of vaulted biaryl ligands via the Snieckus phenol synthesis. | Organic letters 20050203 |
| Aminopeptidase activity in the postmortem brain of human heroin addicts. | Neurochemistry international 20050201 |
| Directed evolution of Pseudomonas aeruginosa lipase for improved amide-hydrolyzing activity. | Protein engineering, design & selection : PEDS 20050201 |
| Intramolecular rearrangement for regioselective complexation by intramolecular CH/pi interaction in a hydrophobic cavity of a ruthenium coordination sphere. | Chemistry (Weinheim an der Bergstrasse, Germany) 20041203 |
| Nucleophilic aromatic substitution on aryl-amido ligands promoted by oxidizing osmium(IV) centers. | Inorganic chemistry 20040920 |
| In vitro and in vivo characterization of a novel naphthylamide ATP-sensitive K+ channel opener, A-151892. | British journal of pharmacology 20040901 |
| Identification of [(naphthalene-1-carbonyl)-amino]-acetic acid derivatives as nonnucleoside inhibitors of HCV NS5B RNA dependent RNA polymerase. | Bioorganic & medicinal chemistry letters 20040816 |
| Dynamic kinetic resolution of atropisomeric amides. | Organic letters 20040610 |
| Highly reactive cysteine residues are part of the substrate binding site of mammalian dipeptidyl peptidases III. | The international journal of biochemistry & cell biology 20040301 |
| 4-Amino cyclohexylglycine analogues as potent dipeptidyl peptidase IV inhibitors. | Bioorganic & medicinal chemistry letters 20040105 |
| Peptidase activity in various species of dairy thermophilic lactobacilli. | Journal of applied microbiology 20040101 |
| Two dialkoxynaphthalene aldehydes as backbone amide linkers for solid-phase synthesis. | Journal of combinatorial chemistry 20040101 |
| Neuron-specific aminopeptidase and puromycin-sensitive aminopeptidase in rat brain development. | Neurochemical research 20030601 |
| An EORTC-ECSG phase I study of LU 79553 administered every 21 or 42 days in patients with solid tumours. | European journal of cancer (Oxford, England : 1990) 20030401 |
| Fluorometric assay using naphthylamide substrates for assessing novel venom peptidase activities. | Toxicon : official journal of the International Society on Toxinology 20021101 |
| Uptake and intracellular fate of gelonin, a ribosome-inactivating protein, in rat liver. | Biochemical and biophysical research communications 20020906 |
| Lysosomal Ca(2+) stores in bovine corneal endothelium. | Investigative ophthalmology & visual science 20020701 |
| Stereodynamics of bond rotation in tertiary aromatic amides. | Chemistry (Weinheim an der Bergstrasse, Germany) 20020315 |
| Identification, purification, and molecular cloning of N-1-naphthylphthalmic acid-binding plasma membrane-associated aminopeptidases from Arabidopsis. | Plant physiology 20020301 |
| Internalization and stepwise degradation of heparan sulfate proteoglycans in rat hepatocytes. | Biochimica et biophysica acta 20011219 |
| Discovery of novel, orally active dual NK1/NK2 antagonists. | Bioorganic & medicinal chemistry letters 20011022 |
| Metabolic stabilization of benzylidene ketal M(2) muscarinic receptor antagonists via halonaphthoic acid substitution. | Bioorganic & medicinal chemistry letters 20010903 |
| [Influence of alcohol on brain aminopeptidases. An in vitro study]. | Revista de neurologia 20010601 |
| Synthesis and structure-activity relationships of naphthamides as dopamine D3 receptor ligands. | Journal of medicinal chemistry 20010524 |
| Effects of methylcyclodextrin on lysosomes. | European journal of biochemistry 20010301 |
| L-Tyrosine beta-naphthylamide is a potent competitive inhibitor of tyramine N-(hydroxycinnamoyl)transferase in vitro. | Phytochemistry 20010301 |
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