200,000+ products from a single source!

sales@angenechem.com

Home > Amines > 205391-02-2

205391-02-2

205391-02-2 | Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-bis(acetyloxy)-5,6-diamino-

CAS No: 205391-02-2 Catalog No: AG002A29 MDL No:MFCD05865101

Product Description

Catalog Number:
AG002A29
Chemical Name:
Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-bis(acetyloxy)-5,6-diamino-
CAS Number:
205391-02-2
Molecular Formula:
C24H18N2O7
Molecular Weight:
446.4089
MDL Number:
MFCD05865101
IUPAC Name:
(6'-acetyloxy-5,6-diamino-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl) acetate
InChI:
InChI=1S/C24H18N2O7/c1-11(27)30-13-3-5-16-21(7-13)32-22-8-14(31-12(2)28)4-6-17(22)24(16)18-10-20(26)19(25)9-15(18)23(29)33-24/h3-10H,25-26H2,1-2H3
InChI Key:
PTSUYDXEEKDBQU-UHFFFAOYSA-N
SMILES:
CC(=O)Oc1ccc2c(c1)Oc1c(C32OC(=O)c2c3cc(N)c(c2)N)ccc(c1)OC(=O)C

Properties

Complexity:
779  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
446.111g/mol
Formal Charge:
0
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
446.415g/mol
Monoisotopic Mass:
446.111g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
140A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.3  

Literature

Title Journal
Effects of moderate electrical stimulation on reactive species production by primary rat skeletal muscle cells: cross talk between superoxide and nitric oxide production. Journal of cellular physiology 20120601
[Influence of environmental factors on the generation of nitric oxide in the roots of etiolated pea seedlings]. Prikladnaia biokhimiia i mikrobiologiia 20120101
Endogenous presynaptic nitric oxide supports an anterograde signaling in the central nervous system. Journal of neurochemistry 20110801
Flux of nitric oxide between the necrotrophic pathogen Botrytis cinerea and the host plant. Molecular plant pathology 20110801
Improved measurements of intracellular nitric oxide in intact microvessels using 4,5-diaminofluorescein diacetate. American journal of physiology. Heart and circulatory physiology 20110701
Monitoring of intracellular nitric oxide in leishmaniasis: its applicability in patients with visceral leishmaniasis. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20110101
Interaction of purinergic and nitrergic mechanisms in the caudal nucleus tractus solitarii of rats. Autonomic neuroscience : basic & clinical 20091203
Nitric oxide, induced by wounding, mediates redox regulation in pelargonium leaves. Plant biology (Stuttgart, Germany) 20090901
Visualization and contractile activity of cochlear pericytes in the capillaries of the spiral ligament. Hearing research 20090801
Immunoreactivity for neuronal NOS and fluorescent indication of NO formation in the NTS of juvenile rats submitted to chronic intermittent hypoxia. Autonomic neuroscience : basic & clinical 20090615
Intracellular nitric oxide assessment in whole blood leukocytes by flow cytometry: optimization and applicability to monitor patients with chronic graft nephropathy. Journal of immunological methods 20090415
Use of diaminofluoresceins to detect and measure nitric oxide in low level generating human immune cells. Journal of immunological methods 20090315
Increased NO bioavailability in aging male rats by genistein and exercise training: using 4, 5-diaminofluorescein diacetate. Reproductive biology and endocrinology : RB&E 20090101
The mechanism of helium-induced preconditioning: a direct role for nitric oxide in rabbits. Anesthesia and analgesia 20080901
A mammalian functional nitrate reductase that regulates nitrite and nitric oxide homeostasis. Nature chemical biology 20080701
Floral transition and nitric oxide emission during flower development in Arabidopsis thaliana is affected in nitrate reductase-deficient plants. Plant & cell physiology 20080701
Nitric oxide detection by DAF (diaminofluorescein) fluorescence in human myometrial tissue. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20080601
Developmental changes in endothelium-dependent relaxation of the chicken ductus arteriosus. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080301
Opposing effects of coupled and uncoupled NOS activity on the Na+-K+ pump in cardiac myocytes. American journal of physiology. Cell physiology 20080201
Imaging of nitric oxide in a living vertebrate using a diamino-fluorescein probe. Free radical biology & medicine 20070815
Nitric oxide decreases ammonium release in tadpoles of the clawed frog, Xenopus laevis, Daudin. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20070501
Effect of high-salt diet on vascular relaxation and oxidative stress in mesenteric resistance arteries. Journal of vascular research 20070101
Abscisic acid (ABA) inhibits light-induced stomatal opening through calcium- and nitric oxide-mediated signaling pathways. Nitric oxide : biology and chemistry 20070101
Activation of nitric oxide signaling by the rheumatoid arthritis shared epitope. Arthritis and rheumatism 20061101
Direct nitric oxide measurement in human spermatozoa: flow cytometric analysis using the fluorescent probe, diaminofluorescein. International journal of andrology 20061001
Nitric oxide is formed in Medicago truncatula-Sinorhizobium meliloti functional nodules. Molecular plant-microbe interactions : MPMI 20060901
Mechanisms underlying nebivolol-induced endothelial nitric oxide synthase activation in human umbilical vein endothelial cells. Clinical and experimental pharmacology & physiology 20060801
Schistosoma mansoni: use of a fluorescent indicator to detect nitric oxide and related species in living parasites. Experimental parasitology 20060601
Inhibitory effects of saponins from Anemarrhena asphodeloides Bunge on the growth of vascular smooth muscle cells. Biomedical and environmental sciences : BES 20060601
The free-radical scavenger, edaravone, augments NO release from vascular cells and platelets after laser-induced, acute endothelial injury in vivo. Platelets 20060501
Nitric oxide synthase localization in the rat neutrophils: immunocytochemical, molecular, and biochemical studies. Journal of leukocyte biology 20060301
Solving an enigma: arterial pole development in the zebrafish heart. Developmental biology 20060215
Neural tube closure depends on nitric oxide synthase activity. Journal of neurochemistry 20060101
Rapid and reactive nitric oxide production by astrocytes in mouse neocortical slices. Glia 20051115
Performance of diamino fluorophores for the localization of sources and targets of nitric oxide. Free radical biology & medicine 20050201
Effect of bradykinin on nitric oxide production, urea synthesis and viability of rat hepatocyte cultures. BMC physiology 20050101
Rodent and human mast cells produce functionally significant intracellular reactive oxygen species but not nitric oxide. The Journal of biological chemistry 20041119
Impact of cirrhosis on the development of experimental hepatic metastases by B16F1 melanoma cells in C57BL/6 mice. Hepatology (Baltimore, Md.) 20041101
Hepatocyte growth factor stimulates nitric oxide production through endothelial nitric oxide synthase activation by the phosphoinositide 3-kinase/Akt pathway and possibly by mitogen-activated protein kinase kinase in vascular endothelial cells. Hypertension research : official journal of the Japanese Society of Hypertension 20041101
Direct intracellular nitric oxide detection in isolated adult cardiomyocytes: flow cytometric analysis using the fluorescent probe, diaminofluorescein. Journal of molecular and cellular cardiology 20041001
Cellular and subcellular localization of endogenous nitric oxide in young and senescent pea plants. Plant physiology 20040901
Nitric oxide is involved in growth regulation and re-orientation of pollen tubes. Development (Cambridge, England) 20040601
Nicotinic receptor mediated stimulation of NO-generation in neurons of rat thoracic dorsal root ganglia. Neuroscience letters 20040506
Angiotensin II stimulates calcium and nitric oxide release from Macula densa cells through AT1 receptors. Hypertension (Dallas, Tex. : 1979) 20040301
Adiponectin stimulates production of nitric oxide in vascular endothelial cells. The Journal of biological chemistry 20031107
Visualization of nitric oxide production and intracellular calcium in juxtamedullary afferent arteriolar endothelial cells. Acta physiologica Scandinavica 20031101
Leukocyte behavior in angiogenic vessels is affected by tumor-derived nitric oxide. The Japanese journal of physiology 20031001
Formation of hydrogen peroxide and nitric oxide in rat skeletal muscle cells during contractions. Free radical biology & medicine 20030901
Mislocalization of eNOS and upregulation of cerebral vascular Ca2+ channel activity in angiotensin-hypertension. Hypertension (Dallas, Tex. : 1979) 20030501
Reactive oxygen species-mediated regulation of eNOS and iNOS expression in multicellular prostate tumor spheroids. International journal of cancer 20030410
Attenuation of neuropathic pain by the nociceptin/orphanin FQ antagonist JTC-801 is mediated by inhibition of nitric oxide production. The European journal of neuroscience 20030401
Activation of the cGMP/nitric oxide signal transduction system by nicotine in the retina. Visual neuroscience 20030101
Nonendothelial source of nitric oxide in arterioles but not in venules: alternative source revealed in vivo by diaminofluorescein microfluorography. Circulation research 20021213
In situ localization of nitric oxide synthase and direct evidence of NO production in rat retinal ganglion cells. Brain research 20020419
Oxidative stress in glial cultures: detection by DAF-2 fluorescence used as a tool to measure peroxynitrite rather than nitric oxide. Glia 20020415
Hydrogen peroxide induces a rapid production of nitric oxide in mung bean (Phaseolus aureus). Nitric oxide : biology and chemistry 20020301
Nitric oxide and abscisic acid cross talk in guard cells. Plant physiology 20020301
Nitric oxide production mediated by nitrate reductase in the green alga Chlamydomonas reinhardtii: an alternative NO production pathway in photosynthetic organisms. Plant & cell physiology 20020301
Mitochondrial nitric oxide localization in H9c2 cells revealed by confocal microscopy. Biochemical and biophysical research communications 20020125
Simultaneous detection of both nitric oxide and reactive oxygen species in guinea pig vestibular sensory cells. ORL; journal for oto-rhino-laryngology and its related specialties 20020101
Neuronal nitric oxide synthase immunohistochemistry and 4,5-diaminofluorescein diacetate: tools for nitric oxide research. Journal of neuroscience methods 20011115
Signaling pathway for nitric oxide generation with simulated ischemia in flow-adapted endothelial cells. American journal of physiology. Heart and circulatory physiology 20011101
Serotonin-induced nitric oxide production in the ventral nerve cord of the earthworm, Eisenia fetida. Neuroscience research 20011001
Characterization of basal nitric oxide production in living cells. Biochimica et biophysica acta 20010926
Visualization of nitric oxide production in the earthworm ventral nerve cord. Neuroscience research 20010601
Increased nitric oxide production in nasal epithelial cells from allergic patients--RT-PCR analysis and direct imaging by a fluorescence indicator: DAF-2 DA. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20010601
Detection of nitric oxide in the guinea pig inner ear, using a combination of aldehyde fixative and 4,5-diaminofluorescein diacetate. Acta oto-laryngologica 20010601
Nitric oxide production by human peripheral blood mononuclear cells. Annals of the Academy of Medicine, Singapore 20010501
Direct evidence of nitric oxide production in the guinea pig organ of Corti. Acta oto-laryngologica 20010401
Nitric oxide in guinea pig vestibular sensory cells following gentamicin exposure in vitro. Acta oto-laryngologica 20010401
Photoactivation and calcium sensitivity of the fluorescent NO indicator 4,5-diaminofluorescein (DAF-2): implications for cellular NO imaging. FEBS letters 20010302
Nitric oxide distribution and production in the guinea pig cochlea. Hearing research 20010301
Nitrosative stress by cyclosporin A in the endothelium: studies with the NO-sensitive probe diaminofluorescein-2/diacetate using flow cytometry. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010101

Related Products

© 2019 Angene International Limited. All rights Reserved.