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Home > Other Building Blocks > 1984-15-2
1984-15-2 | Phosphonic acid, P,P'-methylenebis-
CAS No: 1984-15-2 Catalog No: AG002BI5 MDL No:MFCD00002139
Product Description
Catalog Number:
AG002BI5
Chemical Name:
Phosphonic acid, P,P'-methylenebis-
CAS Number:
1984-15-2
Molecular Formula:
CH6O6P2
Molecular Weight:
176.0023
MDL Number:
MFCD00002139
IUPAC Name:
phosphonomethylphosphonic acid
InChI:
InChI=1S/CH6O6P2/c2-8(3,4)1-9(5,6)7/h1H2,(H2,2,3,4)(H2,5,6,7)
InChI Key:
MBKDYNNUVRNNRF-UHFFFAOYSA-N
SMILES:
OP(=O)(CP(=O)(O)O)O
EC Number:
217-851-0
UNII:
73OS0QIN3O
Properties
Complexity:
152
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
175.964g/mol
Formal Charge:
0
Heavy Atom Count:
9
Hydrogen Bond Acceptor Count:
6
Hydrogen Bond Donor Count:
4
Isotope Atom Count:
0
Molecular Weight:
176.001g/mol
Monoisotopic Mass:
175.964g/mol
Rotatable Bond Count:
2
Topological Polar Surface Area:
115A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-3.3
Literature
| Title | Journal |
|---|---|
| Technetium-99 conjugated with methylene diphosphonate inhibits receptor activator of nuclear factor-κB ligand-induced osteoclastogenesis. | Clinical and experimental pharmacology & physiology 20121001 |
| Methylenebisphosphonate and triphosphate derivatives of the mevalonate pathway are substrates of yeast UTP:glucose-1-phosphate uridylyltransferase. | Biochimie 20120901 |
| Use of 1H and 31P HRMAS to evaluate the relationship between quantitative alterations in metabolite concentrations and tissue features in human brain tumour biopsies. | Analytical and bioanalytical chemistry 20120701 |
| Methylene diphosphonate-conjugated adriamycin liposomes: preparation, characteristics, and targeted therapy for osteosarcomas in vitro and in vivo. | Biomedical microdevices 20120601 |
| A classification method for neurogenic heterotopic ossification of the hip. | Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology 20120601 |
| Methylenebisphosphonates with dienone pharmacophore: synthesis, structure, antitumor and fluorescent properties. | Archiv der Pharmazie 20120501 |
| The IGR-CaP1 xenograft model recapitulates mixed osteolytic/blastic bone lesions observed in metastatic prostate cancer. | Neoplasia (New York, N.Y.) 20120501 |
| Prospective evaluation of (99m)Tc MDP scintigraphy, (18)F NaF PET/CT, and (18)F FDG PET/CT for detection of skeletal metastases. | Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20120401 |
| Is there a need for dedicated bone imaging in addition to 18F-FDG PET/CT imaging in pediatric sarcoma patients? | Journal of pediatric hematology/oncology 20120301 |
| Periarticular bone changes in osteoarthritis. | HSS journal : the musculoskeletal journal of Hospital for Special Surgery 20120201 |
| Single photon emission computed tomography/computed tomography of the skull in malignant otitis externa. | American journal of otolaryngology 20120101 |
| Modern Detection of Prostate Cancer's Bone Metastasis: Is the Bone Scan Era Over? | Advances in urology 20120101 |
| A simple and efficient method for the long-term preservation of plant cell suspension cultures. | Plant methods 20120101 |
| Chronic mandibular osteomyelitis with suspected underlying synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome: a case report. | Journal of inflammation research 20120101 |
| Histopathologic and Radiologic Assessment of Chemotherapeutic Response in Ewing's Sarcoma: A Review. | Sarcoma 20120101 |
| An unusual case of gallium scan mimicking a bone scan. | Journal of clinical imaging science 20120101 |
| [Immunomodulatory effects of vitamin D3 and bisphosphonates in nutritional osteoporosis in rats]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20120101 |
| Selective polarographic determination of stannous ion in technetium radiopharmaceutical cold kits. | Journal of nuclear medicine technology 20111201 |
| A comprehensive review of techniques for biofunctionalization of titanium. | Journal of periodontal & implant science 20111201 |
| Metabolically stabilized derivatives of phosphatidylinositol 4-phosphate: synthesis and applications. | Chemistry & biology 20111028 |
| Bisphosphonamidate clodronate prodrug exhibits potent anticancer activity in non-small-cell lung cancer cells. | Journal of medicinal chemistry 20111013 |
| Synthesis and evaluation of 99mTc-labelled monoclonal antibody 1D09C3 for molecular imaging of major histocompatibility complex class II protein expression. | Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20111001 |
| Bone scan can be spared in asymptomatic prostate cancer patients with PSA of <=20 ng/ml and Gleason score of <=6 at the initial stage of diagnosis. | Japanese journal of clinical oncology 20111001 |
| Disodium diaqua-bis-(methyl-enedi-phos-pho-nato-κO,O')cobaltate(II) dihydrate. | Acta crystallographica. Section E, Structure reports online 20111001 |
| Dicaesium diaqua-bis-(methyl-ene-diphospho-nato-κO,O')cobaltate(II). | Acta crystallographica. Section E, Structure reports online 20111001 |
| Effect of alpha-tocopherol on bone formation during distraction osteogenesis: a rabbit model. | Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology 20110901 |
| Technetium-99 conjugated with methylene diphosphonate (99Tc-MDP) inhibits experimental choroidal neovascularization in vivo and VEGF-induced cell migration and tube formation in vitro. | Investigative ophthalmology & visual science 20110729 |
| Ordered, mesoporous metal phosphonate materials with microporous crystalline walls for selective separation techniques. | Small (Weinheim an der Bergstrasse, Germany) 20110704 |
| Methylene diphosphonate uptake in a case of vertebral hemangioma: demonstration with hybrid SPECT/CT. | Clinical nuclear medicine 20110701 |
| A portable test system for determination of bacterial endotoxins in 18F-FDG, 99mTc, and lyophilized reagents for labeling with 99mTc. | Journal of nuclear medicine technology 20110601 |
| The biological characterization of (99m)Tc-BnAO-NI as a SPECT probe for imaging hypoxia in a sarcoma-bearing mouse model. | Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20110401 |
| Calix[4]arene methylenebisphosphonic acids as inhibitors of fibrin polymerization. | The FEBS journal 20110401 |
| Studies on 177Lu-labeled methylene diphosphonate as potential bone-seeking radiopharmaceutical for bone pain palliation. | Nuclear medicine and biology 20110401 |
| Poly[bis-[μ(2)-(dimethyl-aza-nium-yl)methyl-enediphospho-nato]magnesium]. | Acta crystallographica. Section E, Structure reports online 20110301 |
| Effects of technetium-99 methylenediphosphonate on cytokine-induced activation of retro-ocular fibroblasts from patients with Graves' ophthalmopathy. | Nuclear medicine communications 20110201 |
| SPECT/CT imaging of the lumbar spine in chronic low back pain: a case report. | Chiropractic & manual therapies 20110101 |
| Asymmetrically increased uptake in upper extremities on (99m)Tc-MDP bone scintigraphy caused by intra-arterial injection: different uptake patterns in three cases. | Revista espanola de medicina nuclear 20110101 |
| Molecular SPECT Imaging: An Overview. | International journal of molecular imaging 20110101 |
| Cancer-induced bone pain sequentially activates the ERK/MAPK pathway in different cell types in the rat spinal cord. | Molecular pain 20110101 |
| Vaccine-induced antibodies linked to bovine neonatal pancytopenia (BNP) recognize cattle major histocompatibility complex class I (MHC I). | Veterinary research 20110101 |
| Synthesis of methylenebis(phosphonate) analogues of 2-, 4-, and 6-pyridones of nicotinamide adenine dinucleotide. | Nucleosides, nucleotides & nucleic acids 20110101 |
| Motion-tracking technique in unrestrained small-animal single-photon emission computed tomography. | Reviews in the neurosciences 20110101 |
| Bone Scan 'Hot Spot' at the Superior Lateral Orbital Margin Fronto-zygomatic Suture Uptake Characterized with Tc-99m MDP SPECT/CT. | World journal of nuclear medicine 20110101 |
| Advances in drug design of radiometal-based imaging agents for bone disorders. | International journal of molecular imaging 20110101 |
| TETA analogue containing one methylenephosphonate pendant arm: Lanthanide complexes and biological evaluation of its 153Sm and 166Ho complexes. | European journal of medicinal chemistry 20101201 |
| Clinical impact of radiolabeled anti-CD4 antibodies in the diagnosis of rheumatoid arthritis. | The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of... 20101201 |
| Rhabdomyolysis after laparoscopic radical nephrectomy -A case report-. | Korean journal of anesthesiology 20101201 |
| Periodic mesoporous titanium phosphonate spheres for high dispersion of CuO nanoparticles. | Dalton transactions (Cambridge, England : 2003) 20101028 |
| Uranium pyrophosphate/methylenediphosphonate polyoxometalate cage clusters. | Journal of the American Chemical Society 20100929 |
| Homometallic UO2(2+) diphosphonates assembled under ambient and hydrothermal conditions. | Dalton transactions (Cambridge, England : 2003) 20100921 |
| Epidemiological, clinical, and genetic characteristics of Paget's disease of bone in a rural area of Calabria, Southern Italy. | Journal of endocrinological investigation 20100901 |
| Pyridinium diaqua-bis-(methyl-enediphospho-nato-κO,O')chromate(III) tetra-hydrate. | Acta crystallographica. Section E, Structure reports online 20100801 |
| Enantioselective inhibition of squalene synthase by aziridine analogues of presqualene diphosphate. | The Journal of organic chemistry 20100716 |
| Determination of phosphate compounds in meat products by 31-phosphorus nuclear magnetic resonance spectroscopy with methylenediphosphonic acid after alkaline extraction. | Analytica chimica acta 20100712 |
| Modulation of melanoma cell phospholipid metabolism in response to heat shock protein 90 inhibition. | Oncotarget 20100701 |
| An NMR and DFT investigation on the conformational properties of lanthanide(III) 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetate analogues containing methylenephosphonate pendant arms. | Inorganic chemistry 20100503 |
| Modifications to the dNTP triphosphate moiety: from mechanistic probes for DNA polymerases to antiviral and anti-cancer drug design. | Biochimica et biophysica acta 20100501 |
| Development of bisphosphonates controlled delivery systems for bone implantation: influence of the formulation and process used on in vitro release. | Journal of materials science. Materials in medicine 20100501 |
| Comparisons of Pu(IV) and Ce(IV) diphosphonates. | Inorganic chemistry 20100405 |
| Discordant findings in patients with non-small-cell lung cancer: absolutely normal bone scans versus disseminated bone metastases on positron-emission tomography/computed tomography. | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20100401 |
| When to perform bone scan in patients with newly diagnosed prostate cancer: external validation of the currently available guidelines and proposal of a novel risk stratification tool. | European urology 20100401 |
| Molecular imaging of rheumatoid arthritis by radiolabelled monoclonal antibodies: new imaging strategies to guide molecular therapies. | European journal of nuclear medicine and molecular imaging 20100201 |
| Evaluation of osteoblastic activity around dental implants using bone scintigraphy. | Clinical oral implants research 20100201 |
| Intravenous bisphosphonate therapy does not acutely alter nuclear bone scan results. | Clinical breast cancer 20100201 |
| 48XXYY Syndrome in an Adult with Type 2 Diabetes Mellitus, Unilateral Renal Aplasia, and Pigmentary Retinitis. | Case reports in medicine 20100101 |
| Cancer Response Criteria and Bone Metastases: RECIST 1.1, MDA and PERCIST. | Journal of Cancer 20100101 |
| Hormone refractory carcinoma prostate with peritoneal metastases and malignant ascites without skeletal involvement: A case report and review of literature. | Indian journal of urology : IJU : journal of the Urological Society of India 20100101 |
| Microglia in close vicinity of glioma cells: correlation between phenotype and metabolic alterations. | Frontiers in neuroenergetics 20100101 |
| Efficacy of SPECT over planar bone scan in the diagnosis of solitary vertebral lesions in patients with low back pain. | Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India 20100101 |
| Diffuse hepatic and splenic Tc-99m MDP tracer uptake in case of multiple myeloma. | Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India 20100101 |
| Congenital fibrosarcoma of the chest wall: report of a case. | Journal of cutaneous and aesthetic surgery 20100101 |
| Tc 99m bone scan and fluorodeoxyglucose positron emission tomography in evaluation of disseminated langerhans cell histiocytosis. | Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India 20100101 |
| Combined optical and single photon emission imaging: preliminary results. | Physics in medicine and biology 20091207 |
| Synthetic dinucleotide mRNA cap analogs with tetraphosphate 5',5' bridge containing methylenebis(phosphonate) modification. | Organic & biomolecular chemistry 20091121 |
| Quantitative studies of bone using (99m)Tc-methylene diphosphonate skeletal plasma clearance. | Seminars in nuclear medicine 20091101 |
| Imaging metastatic bone disease from carcinoma of the prostate. | British journal of cancer 20091020 |
| The rabbit biodistribution of a therapeutic dose of zoledronic acid labeled with Tc-99m. | Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20090901 |
| [Technetium 99Tc methylenediphosphonate inhibits osteoclast formation from PBMCs in patients with rheumatoid arthritis]. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20090701 |
| Does magnetic resonance imaging give value-added than bone scintigraphy in the detection of vertebral metastasis? | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20090601 |
| Regulation of intracellular pH during anoxia in rice coleoptiles in acidic and near neutral conditions. | Journal of experimental botany 20090501 |
| Autocrine ATP release coupled to extracellular pyrophosphate accumulation in vascular smooth muscle cells. | American journal of physiology. Cell physiology 20090401 |
| Vitamin D deficiency masquerading as metastatic cancer: a case series. | The American journal of the medical sciences 20090401 |
| Time-dependent effects of imatinib in human leukaemia cells: a kinetic NMR-profiling study. | British journal of cancer 20090324 |
| Sensory-motor polyradiculoneuropathy as the first manifestation of sternum bone plasmacytoma only revealed by bone scintigraphy. | Neuromuscular disorders : NMD 20090101 |
| A comprehensive overview of radioguided surgery using gamma detection probe technology. | World journal of surgical oncology 20090101 |
| Bone turnover markers are correlated with total skeletal uptake of 99mTc-methylene diphosphonate (99mTc-MDP). | BMC medical physics 20090101 |
| Septic shock in pregnancy due to pyogenic sacroiliitis: a case report. | Journal of medical case reports 20090101 |
| Charcot neuroarthropathy triggered by osteomyelitis and/or surgery. | Diabetic medicine : a journal of the British Diabetic Association 20081201 |
| Evaluation of isolated rib lesions with radionuclide-guided biopsy. | The Annals of thoracic surgery 20081001 |
| Does radioiodine treatment change the methylene diphosphonate uptake in a toxic thyroid nodule on bone scintigraphy? | Clinical nuclear medicine 20081001 |
| High-throughput phenotypic characterization of Pseudomonas aeruginosa membrane transport genes. | PLoS genetics 20081001 |
| Phosphonate- and carboxylate-based chelating agents that solubilize (hydr)oxide-bound MnIII. | Environmental science & technology 20080615 |
| Further examples of the failure of surrogates to properly model the structural and hydrothermal chemistry of transuranium elements: insights provided by uranium and neptunium diphosphonates. | Inorganic chemistry 20080602 |
| Characterization of Aquifex aeolicus 4-diphosphocytidyl-2C-methyl-d-erythritol kinase - ligand recognition in a template for antimicrobial drug discovery. | The FEBS journal 20080601 |
| Does cisplatin chemotherapy decrease the MDP uptake of normal bone? An experimental study. | Annals of nuclear medicine 20080601 |
| Hepatitis C virus helicase/NTPase: an efficient expression system and new inhibitors. | Biochemistry. Biokhimiia 20080601 |
| Synthesis of bisphosphonate derivatives of ATP by T4 DNA ligase, ubiquitin activating enzyme (E1) and other ligases. | Biochemical pharmacology 20080515 |
| Synthesis, potentiometric, kinetic, and NMR Studies of 1,4,7,10-tetraazacyclododecane-1,7-bis(acetic acid)-4,10-bis(methylenephosphonic acid) (DO2A2P) and its complexes with Ca(II), Cu(II), Zn(II) and lanthanide(III) ions. | Inorganic chemistry 20080505 |
| Sensitive detection of phosphopeptides by matrix-assisted laser desorption/ionization mass spectrometry: use of alkylphosphonic acids as matrix additives. | Rapid communications in mass spectrometry : RCM 20080401 |
| Molybdophosphonate clusters as building blocks in the oxomolybdate-organodiphosphonate/cobalt(II)-organoimine system: structural influences of secondary metal coordination preferences and diphosphonate tether lengths. | Inorganic chemistry 20080204 |
| Diagnostic value of magnetic resonance imaging and scintigraphy in patients with metastatic breast cancer of the axial skeleton: a comparative study. | Medical oncology (Northwood, London, England) 20080101 |
| Effects of Yunke (technetium-99 conjugated with methylene diphosphonate; (99)Tc-MDP) and/or colloidal chromic phosphate phosphonium-32, alone and in combination, in rats with adjuvant arthritis. | Clinical and experimental pharmacology & physiology 20080101 |
| [Inhibition of alkaline phosphatase by thioureido derivatives of methylenebisphosphonic acid]. | Bioorganicheskaia khimiia 20080101 |
| Hypertrophic osteoarthropathy as the cause of a super scan of the bone in a patient with prostate cancer: a case report. | Journal of medical case reports 20080101 |
| Pneumococcal sacroiliitis in a 4-year-old boy. | Scandinavian journal of rheumatology 20080101 |
| Childhood osteomyelitis-incidence and differentiation from other acute onset musculoskeletal features in a population-based study. | BMC pediatrics 20080101 |
| Erdheim-Chester disease: symmetric uptake in the (99m)Tc-MDP bone scan. | Hellenic journal of nuclear medicine 20080101 |
| Photo-induced lipid peroxidation of erythrocyte membranes by a bis-methanophosphonate fullerene. | Toxicology in vitro : an international journal published in association with BIBRA 20071201 |
| A Case Report of Reiter's Syndrome with Progressive Myelopathy. | Journal of clinical neurology (Seoul, Korea) 20071201 |
| Technetium Tc 99m methylene diphosphonate bone scintigraphy of rhabdomyolysis after near-drowning in cold seawater. | The American journal of emergency medicine 20070901 |
| Correlation of bone SPECT scintigraphy with histopathology of the ethmoid bulla: preliminary investigation. | The Annals of otology, rhinology, and laryngology 20070901 |
| PET-CT in pediatric Langerhans cell histiocytosis. | Pediatric radiology 20070701 |
| Effect of age and gender on the number and distribution of sites in Paget's disease of bone. | The British journal of radiology 20070701 |
| Exposure of veterinary personnel to ionising radiation during bone scanning of horses by nuclear scintigraphy with 99mtechnetium methylene diphosphonate. | The Veterinary record 20070616 |
| Alpha-substituted phosphonate analogues of lysophosphatidic acid (LPA) selectively inhibit production and action of LPA. | ChemMedChem 20070501 |
| Characterization of focal bone lesions in the axial skeleton: performance of planar bone scintigraphy compared with SPECT and SPECT fused with CT. | AJR. American journal of roentgenology 20070501 |
| Rapid characterization of alkylpolyphosphonates by CZE with indirect photometric and mass spectrometric detection. | Electrophoresis 20070201 |
| Metabolic fingerprints of altered brain growth, osmoregulation and neurotransmission in a Rett syndrome model. | PloS one 20070101 |
| Binding of substrate at the effector site of pyrophosphatase increases the rate of its hydrolysis at the active site. | Biochemistry. Biokhimiia 20070101 |
| ATP as effector of inorganic pyrophosphatase of Escherichia coli. The role of residue Lys112 in binding effectors. | Biochemistry. Biokhimiia 20070101 |
| Abnormalities in bone mineral density distribution and bone scintigraphy in patients with childhood onset hypopituitarism. | Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry 20070101 |
| Ewing's sarcoma of the third metatarsal: a case report and review of the literature. | Tumori 20070101 |
| Decrease in oxidative phosphorylation yield in presence of butyrate in perfused liver isolated from fed rats. | BMC physiology 20070101 |
| [Calix[4]arene methylenebisphosphonic acids: the features of alkaline phosphatases inhibition]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20070101 |
| Development of a novel 99mTc-chelate-conjugated bisphosphonate with high affinity for bone as a bone scintigraphic agent. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20061201 |
| Influence of phosphonation and phosphation on surface acid-base and morphological properties of CaO as investigated by in situ FTIR spectroscopy and electron microscopy. | Journal of colloid and interface science 20061101 |
| Acid resistance of erbium-doped yttrium aluminum garnet laser-treated and phosphoric acid-etched enamels. | The Angle orthodontist 20061101 |
| Synthesis of bisphosphonate derivatives of ATP by T4 RNA ligase. | FEBS letters 20061016 |
| Metastatic pulmonary calcification in a dialysis patient: case report and a review. | Hemodialysis international. International Symposium on Home Hemodialysis 20061001 |
| Growth modification of the mandible with ultrasound in baboons: a preliminary report. | American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 20061001 |
| Cytotoxic and genotoxic effects induced by stannous chloride associated to nuclear medicine kits. | Nuclear medicine and biology 20061001 |
| Novel chikungunya virus variant in travelers returning from Indian Ocean islands. | Emerging infectious diseases 20061001 |
| Nuclear medicine methods for evaluation of skeletal infection among other diagnostic modalities. | The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of... 20060901 |
| Synthesis of trans-1,2-cyclohexyldinitrilo tetramethylene phosphonic acid and its radiolabelling with 99mTc for the detection of skeletal metastases. | Nuclear medicine communications 20060801 |
| Usefulness of 18F-FDG PET-directed skeletal biopsy for metastatic neoplasm. | Academic radiology 20060801 |
| Solitary bone metastasis beneath the shoulder shield: coincidence or cause? | Current oncology (Toronto, Ont.) 20060801 |
| Synthesis and characterization of octa- and hexanuclear polyoxomolybdate wheels: role of the inorganic template and of the counterion. | Inorganic chemistry 20060724 |
| Monoglycosyl, diglycosyl, and dinucleoside methylenediphosphonates: direct synthesis and antiviral activity. | Carbohydrate research 20060703 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Synthesis of methylenebis(phosphonate) analogs of dinucleotide pyrophosphates. | Current protocols in nucleic acid chemistry 20060401 |
| The role of SPECT/CT with 99mTc-MDP image fusion to diagnose temporomandibular dysfunction. | Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20060201 |
| Characterization of industrial alkylpolyphosphonates by infusion electrospray ionization-ion trap mass spectrometry with identification of the impurities by tandem capillary zone electrophoresis. | Journal of mass spectrometry : JMS 20060101 |
| Use of scintigraphy for diagnosis of equine paranasal sinus disorders. | Veterinary surgery : VS 20060101 |
| The internal thoracic artery skeletonization study: a paired, within-patient comparison [NCT00265499]. | Trials 20060101 |
| Three-level bilateral pediculolysis following osteoporotic lumbar compression fracture. | The spine journal : official journal of the North American Spine Society 20060101 |
| Synthesis and antiviral evaluation of alkoxyalkyl esters of phosphonopropoxymethyl-guanine and phosphonopropoxymethyl-diaminopurine. | Antiviral chemistry & chemotherapy 20060101 |
| [Effect of calixarene-phosphonic acid on Na+, K+-ATPase activity in plasma membranes of the smooth-muscle cells]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20060101 |
| [Methylenebisphosphonic acid alters the pattern of pericellular glycosaminoglycans and binding properties of CD44 in human endothelial cells]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20060101 |
| Is there a role of whole body bone scan in early stages of non small cell lung cancer patients. | Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20060101 |
| Voltammetry as a virtual potentiometric sensor in modelling of a metal-ligand system and refinement of stability constants. Part 4. An electrochemical study of NiII complexes with methylene diphosphonic acid. | Journal of inorganic biochemistry 20051201 |
| Biochemical and imaging alterations of renal bone disease in newly detected predialysis and on maintenance dialysis patients. | Hemodialysis international. International Symposium on Home Hemodialysis 20051001 |
| Cyclic ADP-ribose analogues containing the methylenebisphosphonate linkage: effect of pyrophosphate modifications on Ca2+ release activity. | Journal of medicinal chemistry 20050616 |
| Technetium-99m diphosphonate imaging of psammocarcinoma of probable ovarian origin: case report and literature review. | Clinical nuclear medicine 20050601 |
| Effects of radiosynovectomy with p-32 colloid therapy in hemophilia and rheumatoid arthritis. | Cancer biotherapy & radiopharmaceuticals 20050601 |
| Structure-activity relationships of dinucleotides: Potent and selective agonists of P2Y receptors. | Purinergic signalling 20050601 |
| Solid-state molecular organization and solution behavior of methane-1,1-diphosphonic acid derivatives of heterocyclic amines: the role of the topochemical ring modification and the intramolecular hydrogen bonds in monosubstituted piperid-1-ylmethane-1,1-diphosphonic acids. | Chemistry (Weinheim an der Bergstrasse, Germany) 20050408 |
| Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with organic phosphates and phosphonates. | Bioorganic & medicinal chemistry letters 20050315 |
| Metal-free PPi activates hydrolysis of MgPPi by an Escherichia coli inorganic pyrophosphatase. | Biochemistry. Biokhimiia 20050101 |
| [A cationic cluster of amino acid residues of inorganic pyrophosphatase from Escherichia coli as a possible site of effector binding]. | Bioorganicheskaia khimiia 20050101 |
| 31P MRS analysis of the phospholipid composition of normal human peripheral blood mononuclear cells (PBMC). | Cellular & molecular biology letters 20050101 |
| Calix[4]arene methylenebisphosphonic acids as calf intestine alkaline phosphatase inhibitors. | Organic & biomolecular chemistry 20041107 |
| Solid-state coordination chemistry of the oxomolybdate-organodiphosphonate/nickel-organoimine system: structural influences of the secondary metal coordination cation and diphosphonate tether lengths. | Inorganic chemistry 20041101 |
| Synthesis of acyloxymethyl ester prodrugs of the transferable protein farnesyl transferase substrate farnesyl methylenediphosphonate. | Bioorganic & medicinal chemistry letters 20041004 |
| 99mTc depreotide scan compared with 99mTc-MDP bone scintigraphy for the detection of bone metastases and prediction of response to hormonal treatment in patients with breast cancer. | Nuclear medicine communications 20040801 |
| Elucidating the role of conserved glutamates in H+-pyrophosphatase of Rhodospirillum rubrum. | The Journal of biological chemistry 20040625 |
| Radionuclide imaging of infection. | Journal of nuclear medicine technology 20040601 |
| Cervical involvement in juvenile-onset ankylosing spondylitis with bone scintigraphy. | Rheumatology international 20040501 |
| What is the role of bone scintigraphy in the diagnosis of infected joint prostheses? | Nuclear medicine communications 20040501 |
| Bone scintigraphy in the investigation of occult lameness in the dog. | The Journal of small animal practice 20040501 |
| Bone lesion detection with carrier-added 99mTc-EDTMP in comparison with 99mTc-DPD. | Nuclear medicine communications 20040401 |
| Radioisotopic evaluation of bone repair after experimental surgical trauma. | Journal of applied oral science : revista FOB 20040301 |
| Efficient synthesis of protected cyclopropyl beta-aspartylphosphates. | Organic & biomolecular chemistry 20040221 |
| Some processes of energy saving and expenditure occurring during ethanol perfusion in the isolated liver of fed rats; a Nuclear Magnetic Resonance study. | BMC physiology 20040101 |
| Isoprenoid biosynthesis via the MEP pathway. Synthesis of (3,4)-3,4-dihydroxy-5-oxohexylphosphonic acid, an isosteric analogue of 1-deoxy-D-xylulose 5-phosphate, the substrate of the 1-deoxy-D-xylulose 5-phosphate reducto-isomerase. | Organic & biomolecular chemistry 20031221 |
| Follow-up of collagen crosslink excretion in patients with oral squamous cell carcinoma and analysis of tissue samples. | British journal of cancer 20031103 |
| Solid state coordination chemistry: one-, two-, and three-dimensional materials constructed from molybdophosphonate subunits linked through binuclear copper tetra-2-pyridylpyrazine groups. | Inorganic chemistry 20031020 |
| Gelatin sheet incorporating basic fibroblast growth factor enhances sternal healing after harvesting bilateral internal thoracic arteries. | The Journal of thoracic and cardiovascular surgery 20031001 |
| [A comparison of planar scintigraphy and MRI in the screening of skeletal metastases]. | Tanisal ve girisimsel radyoloji : Tibbi Goruntuleme ve Girisimsel Radyoloji Dernegi yayin organi 20030901 |
| Signal enhancement through heteronuclear polarisation transfer in in-vivo 31P MR spectroscopy of the human brain. | Magma (New York, N.Y.) 20030701 |
| Replacing the pyrophosphate group of HMB-PP by a diphosphonate function abrogates Its potential to activate human gammadelta T cells but does not lead to competitive antagonism. | Bioorganic & medicinal chemistry letters 20030407 |
| Complexation of beryllium(II) ion by phosphinate ligands in aqueous solution. Synthesis and XRPD structure determination of Be[(PhPO2)2CH2](H2O)2. | Inorganic chemistry 20030407 |
| Collagen crosslink excretion and staging of oral cancer. | British journal of cancer 20030407 |
| Biological reactions to a poly(L-lactide)-hydroxyapatite composite: a study in canine mandible. | Journal of biomaterials applications 20030401 |
| Infecton: a 99mTc-ciprofloxacin radiopharmaceutical for the detection of bone infection. | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20030201 |
| Escherichia coli response to exogenous pyrophosphate and analogs. | Journal of molecular microbiology and biotechnology 20030101 |
| Effectory site in Escherichia coli inorganic pyrophosphatase is revealed upon mutation at the intertrimeric interface. | IUBMB life 20030101 |
| Effect of technetium-99 conjugated with methylene diphosphonate on IgM-RF, IgG-RF and IgA-RF. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20030101 |
| Shoulder girdle neoplasms mimicking frozen shoulder syndrome. | Journal of shoulder and elbow surgery 20030101 |
| Synthesis of stable analogues of thiamine di- and triphosphate as tools for probing a new phosphorylation pathway. | Chemistry (Weinheim an der Bergstrasse, Germany) 20021018 |
| Osteoblast culture on polished titanium disks modified with phosphonic acids. | Journal of biomedical materials research 20021001 |
| Aspartyl phosphonates and phosphoramidates: the first synthetic inhibitors of bacterial aspartate-semialdehyde dehydrogenase. | Chembiochem : a European journal of chemical biology 20020902 |
| Acute renal failure with severe loin pain and patchy renal ischemia after anaerobic exercise in patients with or without renal hypouricemia. | Nephron 20020801 |
| Erdheim-Chester disease with prominent pericardial involvement: clinical, radiologic, and histologic findings. | The American journal of the medical sciences 20020801 |
| Determination of the casein content in bovine milk by 31P-NMR. | The Journal of dairy research 20020801 |
| Cytotoxicity and cellular differentiation activity of methylenebis(phosphonate) analogs of tiazofurin and mycophenolic acid adenine dinucleotide in human cancer cell lines. | Cancer letters 20020708 |
| Diagnostic value of 99mTc-methylene diphosphonate and 99mTc-pentavalent DMSA compared with 99mTc-sestamibi for palpable breast lesions. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20020701 |
| Raynaud phenomenon and Behçet disease: diagnosis with technetium Tc 99m methylene diphosphonate bone scan and treatment with continuous sympathetic block. | Archives of dermatology 20020501 |
| Soft tissue uptake on 99mTc methylene diphosphonate bone scan imaging: pictorial review. | Australasian radiology 20020301 |
| Early revascularization of membranous inlay bone graft in canine mandible model. | The Journal of craniofacial surgery 20020301 |
| Novel mycophenolic adenine bis(phosphonate) analogues as potential differentiation agents against human leukemia. | Journal of medicinal chemistry 20020131 |
| Plasmacytoma of the temporal bone: management with a combination of surgery and radiotherapy. | Acta oto-laryngologica 20011201 |
| Factors influencing blood flow in the equine digit and their effect on uptake of 99m technetium methylene diphosphonate into bone. | Equine veterinary journal 20011101 |
| [Carbon-carbon bond formation based on alkenylphosphonates]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20011101 |
| The tetrahymena ribozyme cleaves a 5'-methylene phosphonate monoester approximately 10(2)-fold faster than a normal phosphate diester: implications for enzyme catalysis of phosphoryl transfer reactions. | Biochemistry 20010918 |
| Prevention of heterotopic ossification after spinal cord injury with indomethacin. | Spinal cord 20010701 |
| [A case of rhabdomyolysis associated with influenza A viral infection given an useful early diagnosis by Tc-99m bone agent scintigraphy]. | Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 20010701 |
| Special feature: radiological case of the month. Congenital syphilis presenting as osteomyelitis with normal radioisotope bone scan. | Archives of pediatrics & adolescent medicine 20010501 |
| Adsorption of radiopharmaceuticals to syringes leads to lower administered activity than intended. | Nuclear medicine communications 20010501 |
| Natural and azido fatty acids inhibit phosphate transport and activate fatty acid anion uniport mediated by the mitochondrial phosphate carrier. | The Journal of biological chemistry 20010216 |
| Comparison of radiography and scintigraphy in the diagnosis of dental disorders in the horse. | Equine veterinary journal 20010101 |
| Quantitative studies of bone with the use of 18F-fluoride and 99mTc-methylene diphosphonate. | Seminars in nuclear medicine 20010101 |
| Cytosolic acidification as a signal mediating hyperosmotic stress responses in Dictyostelium discoideum. | BMC cell biology 20010101 |
| Some phosphonic acid analogs as inhibitors of pyrophosphate-dependent phosphofructokinase, a novel target in Toxoplasma gondii. | Biochemical pharmacology 19950106 |
| PPi analogs as inhibitors of human T-lymphotropic virus type III reverse transcriptase. | Antimicrobial agents and chemotherapy 19860501 |
| Antiviral effects of phosphonoformate (PFA, foscarnet sodium). | Pharmacology & therapeutics 19820101 |
| Pyrophosphate analogues as inhibitors of herpes simplex virus type 1 DNA polymerase. | Biochimica et biophysica acta 19800328 |
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